IMP: Integrative Multi-species Prediction

Mus musculus

14 known processes

Ptger1

prostaglandin E receptor 1 (subtype EP1)

(Aliases: 42kDa,Ptgerep1,EP1)

Ensembl: ENSMUSG00000019464
Entrez: 19216
UniProtKB: B2RS62
UniProtKB: P35375

Process Predictions
Disease Predictions

Ptger1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular calcium ion homeostasis	GO:0006874	119	0.653	Mouse
forebrain development	GO:0030900	302	0.563
trachea cartilage morphogenesis	GO:0060535	4	0.479
positive regulation of cell development	GO:0010720	237	0.464
cation homeostasis	GO:0055080	212	0.443	Mouse
morphogenesis of a branching structure	GO:0001763	203	0.405
immune effector process	GO:0002252	321	0.381	Mouse
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.368
positive regulation of nervous system development	GO:0051962	221	0.363
regulation of epithelial cell proliferation	GO:0050678	141	0.360
cellular chemical homeostasis	GO:0055082	215	0.351	Mouse
nephron tubule morphogenesis	GO:0072078	68	0.351
telencephalon development	GO:0021537	186	0.343
leukocyte differentiation	GO:0002521	342	0.335	Mouse
regulation of cell motility	GO:2000145	236	0.334
mesenchyme development	GO:0060485	152	0.334
regulation of membrane potential	GO:0042391	192	0.328
cerebral cortex development	GO:0021987	86	0.315
stem cell differentiation	GO:0048863	268	0.315
regulation of organ morphogenesis	GO:2000027	144	0.302
cellular ion homeostasis	GO:0006873	165	0.292	Mouse
pallium development	GO:0021543	120	0.291
glandular epithelial cell differentiation	GO:0002067	38	0.287
astrocyte fate commitment	GO:0060018	4	0.285
epithelial tube morphogenesis	GO:0060562	303	0.285
metal ion homeostasis	GO:0055065	189	0.281	Mouse
gland development	GO:0048732	330	0.259
axonogenesis	GO:0007409	274	0.258
anion transport	GO:0006820	177	0.255	Mouse
branching morphogenesis of an epithelial tube	GO:0048754	159	0.253
embryonic limb morphogenesis	GO:0030326	126	0.245
transmembrane transport	GO:0055085	412	0.243
paraxial mesodermal cell fate commitment	GO:0048343	2	0.242
cellular homeostasis	GO:0019725	240	0.242	Mouse
ureteric bud development	GO:0001657	94	0.238
neural precursor cell proliferation	GO:0061351	121	0.229
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.228	Mouse
angiogenesis	GO:0001525	201	0.227
t cell differentiation	GO:0030217	174	0.225	Mouse
tube formation	GO:0035148	140	0.220
mesonephric epithelium development	GO:0072163	94	0.218
heart morphogenesis	GO:0003007	178	0.210
cardiac chamber development	GO:0003205	108	0.209
inorganic ion transmembrane transport	GO:0098660	234	0.207
lymphocyte differentiation	GO:0030098	242	0.202	Mouse
neural tube development	GO:0021915	160	0.200
response to molecule of bacterial origin	GO:0002237	143	0.198
appendage development	GO:0048736	166	0.197
leukocyte activation involved in immune response	GO:0002366	126	0.192	Mouse
mesonephric tubule development	GO:0072164	94	0.191
cerebral cortex cell migration	GO:0021795	44	0.187
ossification	GO:0001503	216	0.184	Mouse
blood vessel morphogenesis	GO:0048514	285	0.183
divalent inorganic cation transport	GO:0072511	178	0.179
cellular metal ion homeostasis	GO:0006875	151	0.174	Mouse
stem cell development	GO:0048864	219	0.171
anatomical structure homeostasis	GO:0060249	145	0.167
sensory perception	GO:0007600	245	0.164
adult locomotory behavior	GO:0008344	91	0.163
calcium ion homeostasis	GO:0055074	127	0.159	Mouse
divalent metal ion transport	GO:0070838	172	0.156
regulation of cell migration	GO:0030334	219	0.156
regulation of hormone levels	GO:0010817	211	0.155
morphogenesis of a branching epithelium	GO:0061138	193	0.155
neural tube formation	GO:0001841	108	0.153
morphogenesis of an epithelial sheet	GO:0002011	27	0.153
mesonephric duct formation	GO:0072181	2	0.152
renal system development	GO:0072001	225	0.152
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.151
chemotaxis	GO:0006935	247	0.150
regulation of secretion	GO:0051046	274	0.150	Mouse
ras protein signal transduction	GO:0007265	77	0.148
retina development in camera type eye	GO:0060041	119	0.148
divalent inorganic cation homeostasis	GO:0072507	138	0.148	Mouse
endomembrane system organization	GO:0010256	147	0.148
ion transmembrane transport	GO:0034220	361	0.145
epithelial cell proliferation	GO:0050673	174	0.144
myeloid cell differentiation	GO:0030099	233	0.141
morphogenesis of embryonic epithelium	GO:0016331	159	0.141
mapk cascade	GO:0000165	281	0.140
stem cell proliferation	GO:0072089	117	0.140
regulation of peptide secretion	GO:0002791	77	0.140
urogenital system development	GO:0001655	261	0.139
regulation of antigen receptor mediated signaling pathway	GO:0050854	29	0.138
planar cell polarity pathway involved in pericardium morphogenesis	GO:0061354	2	0.136
cardiac muscle tissue morphogenesis	GO:0055008	44	0.136
regulation of transmembrane transport	GO:0034762	128	0.135
g protein coupled receptor signaling pathway	GO:0007186	243	0.134	Mouse Rat
epidermis development	GO:0008544	187	0.134
positive regulation of cellular amine metabolic process	GO:0033240	5	0.134
regulation of cell cycle	GO:0051726	281	0.134
axon guidance	GO:0007411	141	0.131
positive regulation of apoptotic process	GO:0043065	217	0.131
peptide secretion	GO:0002790	114	0.130
regulation of neural retina development	GO:0061074	3	0.129
cell type specific apoptotic process	GO:0097285	268	0.129
carbohydrate homeostasis	GO:0033500	128	0.128
neurotransmitter transport	GO:0006836	76	0.128
cell substrate adhesion	GO:0031589	130	0.127
nephron epithelium morphogenesis	GO:0072088	68	0.127
adaptive immune response	GO:0002250	155	0.126
amide transport	GO:0042886	138	0.126
endocrine pancreas development	GO:0031018	29	0.125
membrane organization	GO:0061024	245	0.125
kidney epithelium development	GO:0072073	121	0.125
regionalization	GO:0003002	337	0.124
hindbrain development	GO:0030902	128	0.122
regulation of cellular amino acid metabolic process	GO:0006521	5	0.122
astrocyte differentiation	GO:0048708	43	0.121
male sex determination	GO:0030238	14	0.121	Mouse
mesenchymal cell proliferation	GO:0010463	44	0.120
multicellular organismal response to stress	GO:0033555	62	0.118
sequestering of calcium ion	GO:0051208	18	0.117
t cell proliferation	GO:0042098	120	0.117
regulation of secretion by cell	GO:1903530	249	0.116	Mouse
regulation of kidney development	GO:0090183	40	0.114
transdifferentiation	GO:0060290	1	0.113
negative regulation of cell proliferation	GO:0008285	296	0.113	Mouse
aortic valve morphogenesis	GO:0003180	4	0.113
ureteric bud morphogenesis	GO:0060675	62	0.113
cardiac ventricle development	GO:0003231	83	0.112
multicellular organismal homeostasis	GO:0048871	164	0.112	Mouse
locomotory behavior	GO:0007626	195	0.112
negative regulation of immune system process	GO:0002683	209	0.111
nephron tubule development	GO:0072080	84	0.110
negative regulation of secretion	GO:0051048	61	0.109	Mouse
action potential	GO:0001508	78	0.109
ameboidal type cell migration	GO:0001667	128	0.109
cellular ketone metabolic process	GO:0042180	84	0.108
b cell differentiation	GO:0030183	78	0.107
positive regulation of stem cell proliferation	GO:2000648	59	0.106
b cell activation	GO:0042113	161	0.105
peptide hormone secretion	GO:0030072	109	0.105
regulation of organelle organization	GO:0033043	289	0.105	Mouse
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.105
kidney rudiment formation	GO:0072003	3	0.105
regulation of cellular amine metabolic process	GO:0033238	20	0.105
digestive system development	GO:0055123	200	0.104
forebrain generation of neurons	GO:0021872	63	0.103
negative regulation of cell migration	GO:0030336	59	0.103
regulation of hydrolase activity	GO:0051336	246	0.102
nuclear transport	GO:0051169	139	0.101
glycosyl compound metabolic process	GO:1901657	246	0.101	Mouse
regulation of retina development in camera type eye	GO:1902866	3	0.101
cytosolic calcium ion homeostasis	GO:0051480	70	0.100	Mouse
myeloid leukocyte differentiation	GO:0002573	119	0.100
regulation of neuron differentiation	GO:0045664	281	0.099
lung development	GO:0030324	164	0.098
organic hydroxy compound transport	GO:0015850	93	0.098
mesonephros development	GO:0001823	97	0.098
multicellular organismal metabolic process	GO:0044236	28	0.097
developmental growth involved in morphogenesis	GO:0060560	138	0.097
endocrine system development	GO:0035270	98	0.096
digestive tract development	GO:0048565	190	0.095
maintenance of location	GO:0051235	89	0.095
hormone secretion	GO:0046879	128	0.094
nephric duct formation	GO:0072179	4	0.094
cell division	GO:0051301	120	0.093
neuromuscular process	GO:0050905	99	0.093
cytokine production	GO:0001816	319	0.092	Mouse
metencephalon development	GO:0022037	89	0.092
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.092
regulation of homeostatic process	GO:0032844	182	0.092	Mouse
regulation of resting membrane potential	GO:0060075	3	0.092
protein localization to nucleus	GO:0034504	121	0.091
planar cell polarity pathway involved in outflow tract morphogenesis	GO:0061347	2	0.091
tendon formation	GO:0035992	4	0.091
regulation of cellular response to stress	GO:0080135	159	0.090
kidney morphogenesis	GO:0060993	83	0.090
organophosphate biosynthetic process	GO:0090407	122	0.090	Mouse
leukocyte apoptotic process	GO:0071887	71	0.090
plasma membrane organization	GO:0007009	90	0.089
glucose homeostasis	GO:0042593	128	0.089
planar cell polarity pathway involved in ventricular septum morphogenesis	GO:0061348	2	0.089
sclerotome development	GO:0061056	4	0.089
cardiac chamber morphogenesis	GO:0003206	93	0.089
skeletal system development	GO:0001501	356	0.089
positive regulation of cell migration	GO:0030335	109	0.088
calcium ion transport into cytosol	GO:0060402	48	0.088
myotube differentiation	GO:0014902	105	0.087
nitrogen compound transport	GO:0071705	271	0.087
regulation of wnt signaling pathway	GO:0030111	123	0.087
wound healing	GO:0042060	157	0.086
tissue remodeling	GO:0048771	102	0.086
oligodendrocyte differentiation	GO:0048709	53	0.086
organic acid transport	GO:0015849	101	0.086
canonical wnt signaling pathway involved in regulation of cell proliferation	GO:0044340	3	0.085
aromatic compound catabolic process	GO:0019439	286	0.085
developmental maturation	GO:0021700	193	0.085
artery development	GO:0060840	53	0.084
insulin secretion	GO:0030073	89	0.084
positive regulation of wnt signaling pathway	GO:0030177	45	0.084
metanephros development	GO:0001656	79	0.083
regulation of carbohydrate metabolic process	GO:0006109	75	0.083
epithelial tube formation	GO:0072175	130	0.083
embryonic appendage morphogenesis	GO:0035113	126	0.083
cellular amino acid metabolic process	GO:0006520	103	0.082
pancreatic pp cell fate commitment	GO:0003329	2	0.082
forebrain neuron differentiation	GO:0021879	52	0.082
embryonic skeletal system morphogenesis	GO:0048704	91	0.082
germ cell development	GO:0007281	185	0.082
mesenchyme morphogenesis	GO:0072132	32	0.081
protein targeting	GO:0006605	143	0.081
regulation of actin filament based process	GO:0032970	99	0.081	Mouse
cytokine secretion	GO:0050663	72	0.081	Mouse
tissue homeostasis	GO:0001894	115	0.081
mesonephric duct morphogenesis	GO:0072180	4	0.080
stem cell maintenance	GO:0019827	130	0.080
sequestering of metal ion	GO:0051238	19	0.080
cation transmembrane transport	GO:0098655	266	0.080
epithelial cell morphogenesis	GO:0003382	41	0.080
protein localization to organelle	GO:0033365	185	0.079
regulation of monocyte extravasation	GO:2000437	2	0.079
positive regulation of cytokine production	GO:0001819	174	0.079	Mouse
neuron projection guidance	GO:0097485	141	0.079
rho protein signal transduction	GO:0007266	32	0.078
protein catabolic process	GO:0030163	221	0.078
leukocyte migration	GO:0050900	124	0.078
negative regulation of nervous system development	GO:0051961	156	0.078
gliogenesis	GO:0042063	141	0.078
renal tubule development	GO:0061326	87	0.078
metanephric loop of henle development	GO:0072236	4	0.078
regulation of peptide transport	GO:0090087	91	0.078
positive regulation of gliogenesis	GO:0014015	27	0.078
transmission of nerve impulse	GO:0019226	76	0.078
renal tubule morphogenesis	GO:0061333	72	0.077
mesenchymal cell differentiation	GO:0048762	107	0.077
embryonic placenta development	GO:0001892	98	0.076
apoptotic signaling pathway	GO:0097190	306	0.076
paraxial mesodermal cell differentiation	GO:0048342	2	0.076
glial cell differentiation	GO:0010001	131	0.076
amine metabolic process	GO:0009308	45	0.075
skeletal muscle organ development	GO:0060538	163	0.075
respiratory system development	GO:0060541	190	0.075
positive regulation of neuron differentiation	GO:0045666	141	0.075
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.075
telencephalon cell migration	GO:0022029	55	0.075
cop9 signalosome assembly	GO:0010387	2	0.074
hindbrain formation	GO:0021576	1	0.074
positive regulation of glial cell differentiation	GO:0045687	21	0.073
organic hydroxy compound metabolic process	GO:1901615	203	0.073
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.072
smoothened signaling pathway	GO:0007224	105	0.072
negative regulation of protein modification process	GO:0031400	163	0.072
regulation of neural precursor cell proliferation	GO:2000177	70	0.072
wnt signaling pathway involved in forebrain neuroblast division	GO:0021874	2	0.072
cation transport	GO:0006812	399	0.072
negative regulation of phosphorylation	GO:0042326	166	0.072
regulation of gliogenesis	GO:0014013	50	0.072
alpha beta t cell activation	GO:0046631	91	0.072	Mouse
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	GO:2000802	1	0.071
homeostasis of number of cells	GO:0048872	210	0.071
purine ribonucleotide metabolic process	GO:0009150	290	0.071	Mouse
cell fate specification	GO:0001708	72	0.071
regulation of cellular component biogenesis	GO:0044087	181	0.071	Mouse
skeletal muscle cell differentiation	GO:0035914	66	0.070
regulation of embryonic development	GO:0045995	71	0.070
somitogenesis	GO:0001756	69	0.070
exocytosis	GO:0006887	121	0.070
central nervous system neuron differentiation	GO:0021953	162	0.070
embryonic epithelial tube formation	GO:0001838	130	0.070
cell fate commitment	GO:0045165	210	0.069
negative regulation of cell development	GO:0010721	169	0.069
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.069
mesonephric tubule morphogenesis	GO:0072171	63	0.069
forebrain cell migration	GO:0021885	58	0.068
response to decreased oxygen levels	GO:0036293	59	0.068
regulation of myeloid cell differentiation	GO:0045637	96	0.068
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.068	Mouse
organelle localization	GO:0051640	179	0.067
actin cytoskeleton organization	GO:0030036	220	0.067	Mouse
response to organic cyclic compound	GO:0014070	198	0.067
nephron tubule formation	GO:0072079	20	0.067
kidney development	GO:0001822	213	0.067
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.067
muscle tissue morphogenesis	GO:0060415	53	0.067
leukocyte mediated immunity	GO:0002443	174	0.066
negative regulation of synaptic vesicle transport	GO:1902804	3	0.066
regulation of protein localization	GO:0032880	231	0.066	Mouse
extrinsic apoptotic signaling pathway	GO:0097191	126	0.066
cartilage morphogenesis	GO:0060536	11	0.065
glutamate receptor signaling pathway	GO:0007215	35	0.065
calcium ion transport	GO:0006816	159	0.065
neural tube closure	GO:0001843	90	0.065
appendage morphogenesis	GO:0035107	149	0.065
dorsal spinal cord development	GO:0021516	20	0.065
developmental programmed cell death	GO:0010623	41	0.065
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	GO:0061350	2	0.065
positive regulation of epithelial cell proliferation involved in lung morphogenesis	GO:0060501	3	0.065
carbohydrate metabolic process	GO:0005975	230	0.065
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.065
positive regulation of branching involved in ureteric bud morphogenesis	GO:0090190	18	0.064
endodermal cell fate specification	GO:0001714	4	0.064
regulation of ion transport	GO:0043269	215	0.064
sensory organ morphogenesis	GO:0090596	242	0.064
positive regulation of organelle organization	GO:0010638	128	0.064
response to acid chemical	GO:0001101	111	0.064	Mouse
mesonephric tubule formation	GO:0072172	11	0.063
branching involved in ureteric bud morphogenesis	GO:0001658	56	0.063
ventricular cardiac muscle tissue morphogenesis	GO:0055010	32	0.063
small gtpase mediated signal transduction	GO:0007264	97	0.063
camera type eye development	GO:0043010	266	0.063
cellular response to lipid	GO:0071396	145	0.063	Mouse
mesenchymal cell development	GO:0014031	93	0.062
carbohydrate derivative biosynthetic process	GO:1901137	183	0.062	Mouse
wnt signaling pathway calcium modulating pathway	GO:0007223	2	0.062
sensory perception of pain	GO:0019233	47	0.062
renal vesicle induction	GO:0072034	3	0.062
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process	GO:2000763	1	0.062
regulation of apoptotic signaling pathway	GO:2001233	197	0.061
activation of immune response	GO:0002253	138	0.061
limb morphogenesis	GO:0035108	149	0.061
regulation of stem cell proliferation	GO:0072091	78	0.061
negative regulation of homeostatic process	GO:0032845	71	0.061
tube closure	GO:0060606	91	0.061
neuron migration	GO:0001764	122	0.061
stress activated protein kinase signaling cascade	GO:0031098	81	0.060
regulation of system process	GO:0044057	200	0.060	Mouse
negative regulation of epithelial cell proliferation	GO:0050680	64	0.060
hair follicle development	GO:0001942	85	0.060
cell adhesion	GO:0007155	329	0.060
lymphocyte proliferation	GO:0046651	164	0.060
negative regulation of cell motility	GO:2000146	61	0.059
regulation of cellular ketone metabolic process	GO:0010565	66	0.059
vesicle localization	GO:0051648	86	0.059
cardiac right atrium morphogenesis	GO:0003213	3	0.059
regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045898	2	0.058
response to transforming growth factor beta	GO:0071559	88	0.058
developmental cell growth	GO:0048588	84	0.058
positive regulation of protein modification process	GO:0031401	299	0.058
lung induction	GO:0060492	3	0.058
regulation of branching involved in ureteric bud morphogenesis	GO:0090189	22	0.058
establishment of planar polarity involved in nephron morphogenesis	GO:0072046	1	0.058
signal transduction in absence of ligand	GO:0038034	55	0.058
negative regulation of growth	GO:0045926	99	0.057
synapse organization	GO:0050808	125	0.057
planar cell polarity pathway involved in cardiac right atrium morphogenesis	GO:0061349	2	0.056
primary neural tube formation	GO:0014020	95	0.056
regulation of lymphocyte apoptotic process	GO:0070228	41	0.056
negative regulation of secretion by cell	GO:1903531	54	0.056	Mouse
negative regulation of intracellular signal transduction	GO:1902532	167	0.056
cardiac ventricle morphogenesis	GO:0003208	50	0.056
spinal cord development	GO:0021510	81	0.056
skeletal system morphogenesis	GO:0048705	203	0.056
lymphocyte apoptotic process	GO:0070227	54	0.056
cofactor transport	GO:0051181	4	0.055
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.055
bronchus development	GO:0060433	10	0.054
regulation of mesenchymal cell proliferation	GO:0010464	37	0.054
regulation of morphogenesis of a branching structure	GO:0060688	53	0.054
regulation of mitotic cell cycle	GO:0007346	126	0.054
neural crest cell differentiation	GO:0014033	54	0.054
regulation of cytokine production	GO:0001817	266	0.054	Mouse
spermatogenesis	GO:0007283	284	0.054
regulation of transporter activity	GO:0032409	57	0.054
forebrain neuron development	GO:0021884	30	0.054
t cell activation	GO:0042110	289	0.053	Mouse
mitral valve development	GO:0003174	4	0.053
positive regulation of cell cycle	GO:0045787	92	0.053
cytoplasmic transport	GO:0016482	234	0.053
organonitrogen compound biosynthetic process	GO:1901566	192	0.053	Mouse
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.052	Mouse
inorganic cation transmembrane transport	GO:0098662	207	0.052
metanephric tubule development	GO:0072170	18	0.052
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.052	Mouse
male gamete generation	GO:0048232	285	0.052
immune response activating cell surface receptor signaling pathway	GO:0002429	72	0.052
glycoprotein metabolic process	GO:0009100	116	0.052
metanephric epithelium development	GO:0072207	21	0.052
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.051
organelle fission	GO:0048285	170	0.051
morphogenesis of a polarized epithelium	GO:0001738	37	0.051
inner ear morphogenesis	GO:0042472	101	0.051
negative regulation of phosphate metabolic process	GO:0045936	184	0.051
limb development	GO:0060173	166	0.050
immune response regulating cell surface receptor signaling pathway	GO:0002768	80	0.050
respiratory tube development	GO:0030323	167	0.050
positive regulation of gamma aminobutyric acid secretion	GO:0014054	2	0.050
maintenance of cell number	GO:0098727	3	0.050
embryonic eye morphogenesis	GO:0048048	29	0.049
regulation of vesicle mediated transport	GO:0060627	139	0.049
regulation of inflammatory response	GO:0050727	147	0.049	Mouse
apoptotic process involved in morphogenesis	GO:0060561	25	0.049
mitochondrion organization	GO:0007005	134	0.049
endocytosis	GO:0006897	168	0.049
midbrain hindbrain boundary maturation during brain development	GO:0022004	1	0.048
central nervous system vasculogenesis	GO:0022009	3	0.048
positive regulation of cell motility	GO:2000147	116	0.048
release of sequestered calcium ion into cytosol	GO:0051209	42	0.048
epithelial cell development	GO:0002064	159	0.048
regulation of cell activation	GO:0050865	289	0.048
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.047
ear development	GO:0043583	200	0.047
muscle cell proliferation	GO:0033002	52	0.047	Mouse
pancreatic a cell fate commitment	GO:0003326	2	0.047
somatotropin secreting cell differentiation	GO:0060126	4	0.047
peptidyl tyrosine phosphorylation	GO:0018108	143	0.047
regulation of anagen	GO:0051884	1	0.047
compound eye development	GO:0048749	1	0.047
renal inner medulla development	GO:0072053	3	0.047
peptidyl tyrosine modification	GO:0018212	145	0.047
pancreas development	GO:0031016	57	0.046
tertiary branching involved in mammary gland duct morphogenesis	GO:0060748	3	0.046
alpha beta t cell differentiation	GO:0046632	69	0.046	Mouse
oxidation reduction process	GO:0055114	342	0.046
monocyte extravasation	GO:0035696	2	0.046
establishment of protein localization to organelle	GO:0072594	118	0.046
definitive hemopoiesis	GO:0060216	20	0.046
production of molecular mediator of immune response	GO:0002440	103	0.046
connective tissue development	GO:0061448	179	0.046
regulation of striated muscle cell differentiation	GO:0051153	81	0.046
positive regulation of mapk cascade	GO:0043410	170	0.045
organophosphate catabolic process	GO:0046434	232	0.045
regulation of synaptic plasticity	GO:0048167	87	0.045
cellular response to acid chemical	GO:0071229	68	0.045	Mouse
neuronal action potential	GO:0019228	54	0.045
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis	GO:2000764	1	0.045
intracellular protein transport	GO:0006886	204	0.045
response to growth factor	GO:0070848	198	0.045
nucleotide metabolic process	GO:0009117	332	0.045	Mouse
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.045
negative regulation of myeloid cell differentiation	GO:0045638	38	0.044
multicellular organismal signaling	GO:0035637	91	0.044
positive regulation of glycolytic process	GO:0045821	4	0.044
bmp signaling pathway	GO:0030509	93	0.044
organ induction	GO:0001759	21	0.044
peptide transport	GO:0015833	133	0.044
neuroblast differentiation	GO:0014016	2	0.044
cell activation involved in immune response	GO:0002263	126	0.044	Mouse
leukocyte proliferation	GO:0070661	172	0.044
sodium ion transport	GO:0006814	73	0.044
regulation of mesonephros development	GO:0061217	24	0.044
neurohypophysis development	GO:0021985	2	0.044
uterus morphogenesis	GO:0061038	2	0.044
regulation of peptide hormone secretion	GO:0090276	75	0.044
protein modification by small protein conjugation	GO:0032446	187	0.044
epithelial tube branching involved in lung morphogenesis	GO:0060441	28	0.044
positive regulation of kidney development	GO:0090184	28	0.044
limbic system development	GO:0021761	72	0.044
regulation of inward rectifier potassium channel activity	GO:1901979	1	0.044
somite development	GO:0061053	81	0.043
polarity specification of proximal distal axis	GO:0010085	2	0.043
response to pain	GO:0048265	26	0.043
regulation of cell fate commitment	GO:0010453	19	0.043
single organism nuclear import	GO:1902593	95	0.043
regulation of systemic arterial blood pressure by chemoreceptor signaling	GO:0001979	1	0.043
endoderm development	GO:0007492	45	0.043
regulation of ion transmembrane transport	GO:0034765	119	0.043
lung morphogenesis	GO:0060425	50	0.042
cell maturation	GO:0048469	127	0.042
positive regulation of neuron projection development	GO:0010976	79	0.042
regulation of neuron projection development	GO:0010975	169	0.042
mitral valve morphogenesis	GO:0003183	4	0.042
non canonical wnt signaling pathway involved in heart development	GO:0061341	3	0.042
nephron epithelium development	GO:0072009	92	0.042
protein localization to membrane	GO:0072657	108	0.042
regulation of leukocyte differentiation	GO:1902105	159	0.042
lobar bronchus development	GO:0060482	6	0.041
positive regulation of endopeptidase activity	GO:0010950	43	0.041
peptidyl amino acid modification	GO:0018193	336	0.041
mitotic cell cycle	GO:0000278	195	0.041
response to oxidative stress	GO:0006979	123	0.041
positive regulation of stem cell differentiation	GO:2000738	23	0.041
chromatin organization	GO:0006325	206	0.041
positive regulation of mesonephros development	GO:0061213	20	0.041
regulation of epithelial to mesenchymal transition	GO:0010717	22	0.041
metanephric dct cell differentiation	GO:0072240	3	0.041
spleen development	GO:0048536	39	0.041
g protein coupled acetylcholine receptor signaling pathway	GO:0007213	4	0.041
purine ribonucleoside metabolic process	GO:0046128	241	0.041	Mouse
intestinal epithelial cell maturation	GO:0060574	2	0.041
ribose phosphate metabolic process	GO:0019693	291	0.040	Mouse
regulation of ion transmembrane transporter activity	GO:0032412	54	0.040
positive regulation of cellular catabolic process	GO:0031331	148	0.040
canonical wnt signaling pathway	GO:0060070	130	0.040
regulation of hormone secretion	GO:0046883	88	0.040
cellular amine metabolic process	GO:0044106	44	0.040
ensheathment of neurons	GO:0007272	76	0.040
wnt signaling pathway	GO:0016055	188	0.040
outflow tract morphogenesis	GO:0003151	53	0.040
diencephalon development	GO:0021536	63	0.040
nephron development	GO:0072006	109	0.040
establishment of organ orientation	GO:0048561	1	0.040
regulation of oxidative phosphorylation uncoupler activity	GO:2000275	3	0.040
oxygen homeostasis	GO:0032364	2	0.040
regulation of muscle tissue development	GO:1901861	97	0.039
muscle tissue development	GO:0060537	308	0.039
protein modification by small protein conjugation or removal	GO:0070647	207	0.039
positive regulation of mesenchymal cell proliferation	GO:0002053	33	0.039
positive regulation of keratinocyte proliferation	GO:0010838	4	0.039
potassium ion import	GO:0010107	1	0.039
nephron morphogenesis	GO:0072028	69	0.039
negative regulation of ossification	GO:0030279	49	0.039
regulation of neurotransmitter levels	GO:0001505	87	0.039

Ptger1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.066
nervous system disease	DOID:863	0.066
sensory system disease	DOID:0050155	0.042

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