| protein modification by small protein conjugation | GO:0032446 | 187 | 0.126 | |
| protein catabolic process | GO:0030163 | 221 | 0.118 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.112 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.105 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 56 | 0.086 | |
| protein ubiquitination | GO:0016567 | 171 | 0.082 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.078 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.076 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.074 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.071 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.068 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.065 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.059 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.058 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.056 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.055 | |
| trivalent inorganic cation transport | GO:0072512 | 5 | 0.052 | |
| amine metabolic process | GO:0009308 | 45 | 0.048 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.043 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.043 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.041 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.041 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.040 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.039 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.039 | |
| cation transport | GO:0006812 | 399 | 0.038 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.038 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.036 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.036 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.035 | |
| fat cell differentiation | GO:0045444 | 160 | 0.034 | |
| regulation of secretion | GO:0051046 | 274 | 0.034 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.033 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.033 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.033 | |
| positive regulation of protein catabolic process | GO:0045732 | 60 | 0.032 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.032 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.032 | |
| chiasma assembly | GO:0051026 | 6 | 0.032 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.030 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.030 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.029 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.029 | |
| membrane organization | GO:0061024 | 245 | 0.028 | |
| ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway | GO:0043162 | 3 | 0.028 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.028 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.027 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 83 | 0.027 | |
| interspecies interaction between organisms | GO:0044419 | 83 | 0.027 | |
| chromatin modification | GO:0016568 | 187 | 0.027 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.026 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.026 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.026 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.026 | |
| vesicle organization | GO:0016050 | 60 | 0.026 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.025 | |
| substantia nigra development | GO:0021762 | 2 | 0.025 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.025 | |
| positive regulation of protein ubiquitination | GO:0031398 | 27 | 0.025 | |
| protein polyubiquitination | GO:0000209 | 33 | 0.025 | |
| regulation of translation | GO:0006417 | 71 | 0.024 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.024 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.024 | |
| exocytosis | GO:0006887 | 121 | 0.024 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.024 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.023 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.023 | |
| transmembrane transport | GO:0055085 | 412 | 0.023 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.023 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.022 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.022 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.022 | |
| localization within membrane | GO:0051668 | 4 | 0.022 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.022 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.022 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.022 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.021 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.021 | |
| intracellular protein transport | GO:0006886 | 204 | 0.021 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.021 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.021 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.021 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.021 | |
| protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:0042787 | 25 | 0.021 | |
| cilium morphogenesis | GO:0060271 | 102 | 0.020 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.020 | |
| regulation of protein ubiquitination | GO:0031396 | 52 | 0.020 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.019 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.019 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 57 | 0.019 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.019 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.019 | |
| protein refolding | GO:0042026 | 1 | 0.019 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.019 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.019 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.018 | |
| mitochondrion degradation | GO:0000422 | 3 | 0.018 | |
| histone demethylation | GO:0016577 | 13 | 0.018 | |
| negative regulation of multi organism process | GO:0043901 | 68 | 0.018 | |
| histone h2a ubiquitination | GO:0033522 | 3 | 0.018 | |
| regulation of cell growth | GO:0001558 | 91 | 0.018 | |
| positive regulation of protein modification by small protein conjugation or removal | GO:1903322 | 30 | 0.018 | |
| chromatin organization | GO:0006325 | 206 | 0.018 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.018 | |
| cell cycle checkpoint | GO:0000075 | 47 | 0.017 | |
| mapk cascade | GO:0000165 | 281 | 0.017 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.017 | |
| cell division | GO:0051301 | 120 | 0.017 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.017 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.017 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.017 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.017 | |
| histone modification | GO:0016570 | 159 | 0.017 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.017 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.017 | |
| methylation | GO:0032259 | 134 | 0.016 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.016 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.016 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.016 | |
| retrograde transport endosome to golgi | GO:0042147 | 2 | 0.016 | |
| compound eye development | GO:0048749 | 1 | 0.016 | |
| mrna splicing via spliceosome | GO:0000398 | 43 | 0.016 | |
| negative regulation of inclusion body assembly | GO:0090084 | 1 | 0.016 | |
| regulation of protein transport | GO:0051223 | 163 | 0.016 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.016 | |
| activation of nf kappab inducing kinase activity | GO:0007250 | 4 | 0.016 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.016 | |
| dna templated transcription termination | GO:0006353 | 4 | 0.016 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.016 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.016 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.015 | |
| muscle tissue development | GO:0060537 | 308 | 0.015 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.015 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.015 | |
| regulation of cell migration | GO:0030334 | 219 | 0.015 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.015 | |
| nuclear transport | GO:0051169 | 139 | 0.015 | |
| viral process | GO:0016032 | 41 | 0.015 | |
| activation of adenylate cyclase activity | GO:0007190 | 4 | 0.015 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.015 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.015 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.014 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.014 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.014 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 34 | 0.014 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.014 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.014 | |
| renal system development | GO:0072001 | 225 | 0.014 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.014 | |
| endocytosis | GO:0006897 | 168 | 0.014 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.014 | |
| protein acylation | GO:0043543 | 64 | 0.014 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.014 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.014 | |
| regulation of cell motility | GO:2000145 | 236 | 0.014 | |
| macromolecule methylation | GO:0043414 | 120 | 0.014 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.014 | |
| cell adhesion | GO:0007155 | 329 | 0.013 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.013 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.013 | |
| transition metal ion transport | GO:0000041 | 38 | 0.013 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.013 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.013 | |
| cell growth | GO:0016049 | 130 | 0.013 | |
| negative regulation of viral process | GO:0048525 | 23 | 0.013 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.013 | |
| cilium assembly | GO:0042384 | 81 | 0.013 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.013 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.013 | |
| response to radiation | GO:0009314 | 165 | 0.013 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.013 | |
| male gamete generation | GO:0048232 | 285 | 0.013 | |
| spermatogenesis | GO:0007283 | 284 | 0.013 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.013 | |
| regulation of cell projection assembly | GO:0060491 | 38 | 0.013 | |
| organelle localization | GO:0051640 | 179 | 0.013 | |
| skeletal system development | GO:0001501 | 356 | 0.013 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.013 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.013 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.013 | |
| protein localization to membrane | GO:0072657 | 108 | 0.012 | |
| positive regulation of atpase activity | GO:0032781 | 3 | 0.012 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.012 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.012 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.012 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.012 | |
| mrna processing | GO:0006397 | 63 | 0.012 | |
| synaptic transmission | GO:0007268 | 329 | 0.012 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.012 | |
| early endosome to late endosome transport | GO:0045022 | 2 | 0.012 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.012 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.012 | |
| protein localization to organelle | GO:0033365 | 185 | 0.012 | |
| regulation of canonical wnt signaling pathway | GO:0060828 | 82 | 0.012 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.012 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.012 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.012 | |
| t cell activation | GO:0042110 | 289 | 0.012 | |
| translesion synthesis | GO:0019985 | 1 | 0.012 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.012 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.012 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.012 | |
| photoreceptor cell development | GO:0042461 | 40 | 0.012 | |
| positive regulation of cell migration | GO:0030335 | 109 | 0.012 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.012 | |
| cell cycle g1 s phase transition | GO:0044843 | 57 | 0.012 | |
| regulation of cell division | GO:0051302 | 76 | 0.012 | |
| urogenital system development | GO:0001655 | 261 | 0.011 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.011 | |
| regulation of symbiosis encompassing mutualism through parasitism | GO:0043903 | 52 | 0.011 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.011 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.011 | |
| negative regulation of cellular catabolic process | GO:0031330 | 47 | 0.011 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 48 | 0.011 | |
| viral life cycle | GO:0019058 | 36 | 0.011 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.011 | |
| dipeptide transport | GO:0042938 | 2 | 0.011 | |
| dna metabolic process | GO:0006259 | 303 | 0.011 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.011 | |
| response to nutrient levels | GO:0031667 | 109 | 0.011 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.011 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.011 | |
| positive regulation of wnt signaling pathway | GO:0030177 | 45 | 0.011 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.011 | |
| carboxylic acid biosynthetic process | GO:0046394 | 86 | 0.011 | |
| regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:2000058 | 14 | 0.011 | |
| regulation of receptor activity | GO:0010469 | 41 | 0.011 | |
| response to light stimulus | GO:0009416 | 135 | 0.011 | |
| respiratory tube development | GO:0030323 | 167 | 0.011 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.011 | |
| neuron death | GO:0070997 | 154 | 0.011 | |
| asymmetric stem cell division | GO:0098722 | 3 | 0.011 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.011 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.011 | |
| viral budding | GO:0046755 | 1 | 0.011 | |
| translational initiation | GO:0006413 | 24 | 0.011 | |
| cerebral cortex development | GO:0021987 | 86 | 0.010 | |
| protein secretion | GO:0009306 | 111 | 0.010 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.010 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.010 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.010 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.010 | |
| negative regulation of growth | GO:0045926 | 99 | 0.010 | |
| positive regulation of secretion by cell | GO:1903532 | 114 | 0.010 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.010 | |
| regulation of protein secretion | GO:0050708 | 82 | 0.010 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.010 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.010 | |
| protein dealkylation | GO:0008214 | 13 | 0.010 | |
| respiratory system development | GO:0060541 | 190 | 0.010 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 57 | 0.010 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.010 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.010 | |
| forebrain development | GO:0030900 | 302 | 0.010 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.010 | |
