Mus musculus

82 known processes

Diablo

diablo homolog (Drosophila)

(Aliases: Smac,0610041G12Rik,AU040403,1700006L01Rik)

Diablo biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein processingGO:00164851630.206
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.189
defense response to other organismGO:00985421970.186
protein ubiquitinationGO:00165671710.160
regulation of protein maturationGO:1903317960.158
response to organic cyclic compoundGO:00140701980.154
cellular response to dna damage stimulusGO:00069742070.153
macromolecule catabolic processGO:00090572810.129
defense response to bacteriumGO:00427421190.128
negative regulation of protein processingGO:0010955790.120
protein modification by small protein conjugation or removalGO:00706472070.118
cellular response to hormone stimulusGO:00328701500.101
ripoptosome assembly involved in necroptotic processGO:190102660.098
negative regulation of necrotic cell deathGO:0060547110.093
positive regulation of canonical wnt signaling pathwayGO:0090263290.091
protein maturationGO:00516041760.089
protein modification by small protein conjugationGO:00324461870.088
germ cell developmentGO:00072811850.084
spermatogenesisGO:00072832840.084
placenta developmentGO:00018901400.084
negative regulation of neuron deathGO:1901215980.081
regulation of wnt signaling pathwayGO:00301111230.080
regulation of protein processingGO:0070613960.078
negative regulation of protein maturationGO:1903318790.078
inhibition of cysteine type endopeptidase activityGO:009734010.068
maintenance of protein location in nucleusGO:005145720.068
negative regulation of hydrolase activityGO:0051346710.065
response to steroid hormoneGO:0048545560.064
regulation of neuron deathGO:19012141340.064
negative regulation of cellular protein metabolic processGO:00322692470.063
negative regulation of proteolysisGO:0045861740.061
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.060
positive regulation of wnt signaling pathwayGO:0030177450.058
cellular response to lipidGO:00713961450.057
negative regulation of neuron apoptotic processGO:0043524920.055
inflammatory responseGO:00069542440.055
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.055
nitrogen compound transportGO:00717052710.053
cellular response to organic cyclic compoundGO:0071407870.050
regulation of reactive oxygen species metabolic processGO:2000377400.048
negative regulation of phosphorylationGO:00423261660.048
regulation of protein ubiquitinationGO:0031396520.048
protein polyubiquitinationGO:0000209330.047
cellular response to steroid hormone stimulusGO:0071383330.047
regulation of cellular senescenceGO:200077260.045
negative regulation of molecular functionGO:00440922580.044
tolerance induction to self antigenGO:000251340.044
negative regulation of endopeptidase activityGO:0010951440.043
regulation of endopeptidase activityGO:0052548890.043
lens fiber cell apoptotic processGO:199008640.043
reactive oxygen species metabolic processGO:0072593840.043
positive regulation of cell activationGO:00508671580.043
protein localization to nucleusGO:00345041210.042
innate immune responseGO:00450871570.042
mitotic cell cycleGO:00002781950.040
positive regulation of protein modification processGO:00314012990.039
lymphocyte differentiationGO:00300982420.039
response to radiationGO:00093141650.039
male gonad developmentGO:0008584880.039
negative regulation of peptidase activityGO:0010466460.039
response to estrogenGO:0043627240.038
detection of stimulusGO:0051606840.038
regulation of proteolysisGO:00301621640.037
aromatic compound catabolic processGO:00194392860.037
neural plate mediolateral regionalizationGO:002199810.037
regulation of kinase activityGO:00435492490.037
positive regulation of lymphocyte activationGO:00512511400.037
retina development in camera type eyeGO:00600411190.036
negative regulation of cell developmentGO:00107211690.036
regulation of protein modification by small protein conjugation or removalGO:1903320570.036
wnt signaling pathwayGO:00160551880.036
smoothened signaling pathwayGO:00072241050.034
developmental growth involved in morphogenesisGO:00605601380.034
regulation of cysteine type endopeptidase activityGO:2000116650.033
positive regulation of mapk cascadeGO:00434101700.033
regulation of system processGO:00440572000.033
negative regulation of cellular component organizationGO:00511291940.032
positive regulation of cell deathGO:00109422240.032
positive regulation of neuron differentiationGO:00456661410.032
regulation of cell activationGO:00508652890.032
programmed necrotic cell deathGO:0097300280.031
skeletal system morphogenesisGO:00487052030.031
organic cyclic compound catabolic processGO:19013612950.031
male sex differentiationGO:00466611090.031
development of primary male sexual characteristicsGO:0046546880.031
regulation of necroptotic processGO:0060544100.031
urogenital system developmentGO:00016552610.031
spermatid developmentGO:00072861080.030
positive regulation of cell projection organizationGO:0031346950.030
regulation of embryonic developmentGO:0045995710.030
epithelium migrationGO:0090132630.029
male gamete generationGO:00482322850.029
cell adhesionGO:00071553290.029
positive regulation of cell developmentGO:00107202370.028
t cell activationGO:00421102890.028
negative regulation of cysteine type endopeptidase activityGO:2000117220.028
cellular response to estrogen stimulusGO:0071391120.028
positive regulation of apoptotic processGO:00430652170.027
stem cell proliferationGO:00720891170.027
circulatory system processGO:00030131970.027
rhythmic processGO:00485111740.027
regulation of blood pressureGO:0008217930.027
regulation of cellular catabolic processGO:00313292420.026
regulation of lymphocyte activationGO:00512492400.026
regulation of stem cell proliferationGO:0072091780.026
stem cell maintenanceGO:00198271300.026
necrotic cell deathGO:0070265300.026
positive regulation of protein phosphorylationGO:00019342420.026
stem cell differentiationGO:00488632680.026
ribose phosphate metabolic processGO:00196932910.026
negative regulation of necroptotic processGO:006054690.026
renal system developmentGO:00720012250.026
protein localization to organelleGO:00333651850.026
mrna metabolic processGO:0016071840.025
nucleobase containing small molecule metabolic processGO:00550863520.025
ovarian follicle developmentGO:0001541400.025
cellular nitrogen compound catabolic processGO:00442702800.025
mesendoderm developmentGO:004838230.025
protein catabolic processGO:00301632210.025
male meiosis iGO:0007141160.025
cell agingGO:0007569350.024
nucleotide metabolic processGO:00091173320.024
cellular macromolecule catabolic processGO:00442652060.024
nucleoside phosphate metabolic processGO:00067533380.024
positive regulation of protein ubiquitinationGO:0031398270.024
muscle cell differentiationGO:00426922610.024
meiotic nuclear divisionGO:00071261150.024
positive regulation of protein modification by small protein conjugation or removalGO:1903322300.024
blood circulationGO:00080151950.024
protein targetingGO:00066051430.024
positive regulation of cellular amine metabolic processGO:003324050.024
maintenance of protein localization in organelleGO:007259520.023
regulation of bindingGO:00510981110.023
positive regulation of programmed cell deathGO:00430682180.023
regulation of apoptotic signaling pathwayGO:20012331970.023
cell type specific apoptotic processGO:00972852680.023
fused antrum stageGO:004816510.023
meiotic cell cycleGO:00513211220.023
spermatid differentiationGO:00485151150.023
protein import into nucleusGO:0006606950.023
rna processingGO:00063961050.023
neuron apoptotic processGO:00514021420.023
regulation of hormone levelsGO:00108172110.022
mesenchyme developmentGO:00604851520.022
bronchus morphogenesisGO:006043420.022
negative regulation of apoptotic signaling pathwayGO:20012341040.022
zymogen inhibitionGO:009734110.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.022
positive regulation of protein kinase activityGO:00458601440.022
negative regulation of reactive oxygen species metabolic processGO:2000378100.022
regulation of cell migrationGO:00303342190.022
tissue migrationGO:0090130680.022
mesenchymal cell developmentGO:0014031930.021
gonad developmentGO:00084061410.021
regulation of cellular amino acid metabolic processGO:000652150.021
positive regulation of b cell tolerance inductionGO:000266320.021
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.021
maternal determination of anterior posterior axis embryoGO:000835820.021
regulation of cell cycleGO:00517262810.021
response to monosaccharideGO:0034284670.021
skeletal system developmentGO:00015013560.020
mesoderm developmentGO:00074981000.020
regulation of ripoptosome assembly involved in necroptotic processGO:190244230.020
response to peptide hormoneGO:00434341270.020
embryonic organ morphogenesisGO:00485622760.020
regulation of cellular amine metabolic processGO:0033238200.020
regulation of lung blood pressureGO:001491620.020
inhibition of cysteine type endopeptidase activity involved in apoptotic processGO:199000110.020
oocyte axis specificationGO:000730920.020
negative regulation of nervous system developmentGO:00519611560.020
activin receptor signaling pathwayGO:0032924180.020
trachea formationGO:006044030.020
neuron deathGO:00709971540.020
macromolecule methylationGO:00434141200.020
response to sterolGO:003631440.020
regulation of cellular component biogenesisGO:00440871810.019
organ regenerationGO:003110020.019
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.019
regulation of cell morphogenesis involved in differentiationGO:00107691510.019
neural precursor cell proliferationGO:00613511210.019
negative regulation of phosphate metabolic processGO:00459361840.019
regionalizationGO:00030023370.019
mesoderm structural organizationGO:004833810.019
t cell differentiationGO:00302171740.019
regulation of neuron apoptotic processGO:00435231220.019
regulation of hydrolase activityGO:00513362460.018
response to acid chemicalGO:00011011110.018
cellular amine metabolic processGO:0044106440.018
organelle fissionGO:00482851700.018
negative regulation of phosphorus metabolic processGO:00105631840.018
kidney developmentGO:00018222130.018
regulation of t cell activationGO:00508631700.018
dna repairGO:00062811070.018
forebrain developmentGO:00309003020.018
translationGO:0006412930.018
chondrocyte hypertrophyGO:000341540.018
ameboidal type cell migrationGO:00016671280.018
regulation of anatomical structure sizeGO:00900661780.018
response to extracellular stimulusGO:00099911270.018
response to organonitrogen compoundGO:00102432460.018
regulation of epithelial cell proliferationGO:00506781410.018
extrinsic apoptotic signaling pathwayGO:00971911260.018
necroptotic processGO:0070266210.017
purine ribonucleoside metabolic processGO:00461282410.017
lipid localizationGO:00108761260.017
regulation of map kinase activityGO:00434051200.017
positive regulation of cell migrationGO:00303351090.017
female gamete generationGO:0007292740.017
multi multicellular organism processGO:00447061090.017
nucleocytoplasmic transportGO:00069131390.017
nuclear transportGO:00511691390.017
heterocycle catabolic processGO:00467002800.017
cartilage developmentGO:00512161400.017
locomotory behaviorGO:00076261950.016
maternal process involved in female pregnancyGO:0060135320.016
development of primary sexual characteristicsGO:00451371430.016
sensory organ morphogenesisGO:00905962420.016
embryonic appendage morphogenesisGO:00351131260.016
negative regulation of protein complex assemblyGO:0031333250.016
methylationGO:00322591340.016
appendage developmentGO:00487361660.016
single organism nuclear importGO:1902593950.016
cellular amino acid metabolic processGO:00065201030.016
molting cycleGO:0042303900.016
epithelial cell migrationGO:0010631630.016
fat cell differentiationGO:00454441600.016
negative regulation of cellular catabolic processGO:0031330470.016
purine containing compound catabolic processGO:00725232130.015
oxidation reduction processGO:00551143420.015
lung morphogenesisGO:0060425500.015
regulation of ion transportGO:00432692150.015
developmental cell growthGO:0048588840.015
regulation of peptide secretionGO:0002791770.015
bone developmentGO:00603481200.015
regulation of cellular ketone metabolic processGO:0010565660.015
myeloid leukocyte activationGO:0002274830.015
positive regulation of stem cell proliferationGO:2000648590.015
germ line stem cell divisionGO:004207820.015
myeloid leukocyte differentiationGO:00025731190.015
female sex differentiationGO:0046660840.015
dna metabolic processGO:00062593030.015
oogenesis stageGO:002260530.015
embryonic limb morphogenesisGO:00303261260.015
adult locomotory behaviorGO:0008344910.015
ribonucleotide metabolic processGO:00092592910.015
positive regulation of t cell differentiationGO:0045582520.015
limb developmentGO:00601731660.015
inorganic cation transmembrane transportGO:00986622070.015
mrna processingGO:0006397630.015
striated muscle tissue developmentGO:00147062930.015
oocyte constructionGO:000730820.014
canonical wnt signaling pathwayGO:00600701300.014
neuron projection extensionGO:1990138640.014
negative regulation of cellular response to growth factor stimulusGO:0090288460.014
trachea developmentGO:0060438180.014
stem cell developmentGO:00488642190.014
amine metabolic processGO:0009308450.014
positive regulation of transferase activityGO:00513471670.014
negative regulation of vasoconstrictionGO:004590620.014
negative regulation of protein metabolic processGO:00512482820.014
negative regulation of intracellular signal transductionGO:19025321670.014
regulation of secretion by cellGO:19035302490.014
glucose metabolic processGO:0006006920.014
tissue homeostasisGO:00018941150.014
regulation of neuron differentiationGO:00456642810.014
response to uvGO:0009411440.014
regulation of ion transmembrane transportGO:00347651190.014
intracellular mrna localizationGO:000829840.014
purine containing compound metabolic processGO:00725213110.014
positive regulation of nervous system developmentGO:00519622210.014
limb morphogenesisGO:00351081490.014
positive regulation of lymphocyte differentiationGO:0045621610.014
positive regulation of cellular amino acid metabolic processGO:004576430.014
male meiosisGO:0007140370.014
maternal placenta developmentGO:0001893200.014
response to alcoholGO:0097305480.014
ovulation cycleGO:0042698590.014
gland developmentGO:00487323300.013
chromatin modificationGO:00165681870.013
apoptotic signaling pathwayGO:00971903060.013
regulation of protein complex assemblyGO:0043254830.013
regulation of b cell tolerance inductionGO:000266120.013
organic hydroxy compound metabolic processGO:19016152030.013
muscle tissue developmentGO:00605373080.013
positive regulation of endothelial cell proliferationGO:0001938170.013
response to insulinGO:00328681000.013
regulation of intracellular protein transportGO:0033157820.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
regulation of organ morphogenesisGO:20000271440.013
regulation of smad protein import into nucleusGO:006039030.013
response to oxygen levelsGO:0070482620.013
epidermis developmentGO:00085441870.013
regulation of mesenchymal cell proliferationGO:0010464370.013
embryonic skeletal system developmentGO:00487061200.013
transforming growth factor beta receptor signaling pathwayGO:0007179710.013
ureteric bud developmentGO:0001657940.013
regulation of mitotic cell cycleGO:00073461260.013
hindbrain developmentGO:00309021280.013
intracellular protein transportGO:00068862040.013
nucleotide catabolic processGO:00091662170.012
blastocyst developmentGO:0001824800.012
negative regulation of defense responseGO:0031348770.012
oogenesisGO:0048477560.012
regulation of protein targetingGO:1903533610.012
pole plasm assemblyGO:000731520.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
regulation of tolerance induction to self antigenGO:000264910.012
embryonic skeletal system morphogenesisGO:0048704910.012
hair follicle developmentGO:0001942850.012
response to light stimulusGO:00094161350.012
regulation of leukocyte differentiationGO:19021051590.012
myeloid dendritic cell activationGO:0001773250.012
regulation of mapk cascadeGO:00434082480.012
acetylcholine transportGO:001587020.012
camera type eye developmentGO:00430102660.012
negative regulation of prostatic bud formationGO:006068640.012
cation transportGO:00068123990.012
response to growth factorGO:00708481980.012
female gonad developmentGO:0008585710.012
regulation of angiogenesisGO:0045765810.012
hormone metabolic processGO:0042445860.012
immune effector processGO:00022523210.012
organelle localizationGO:00516401790.012
organ growthGO:00352651170.012
cation transmembrane transportGO:00986552660.012
connective tissue developmentGO:00614481790.012
posttranscriptional regulation of gene expressionGO:00106081550.012
regulation of membrane potentialGO:00423911920.011
protein importGO:00170381010.011
alpha beta t cell activationGO:0046631910.011
telencephalon developmentGO:00215371860.011
regulation of cell projection organizationGO:00313442060.011
regulation of lymphocyte differentiationGO:00456191070.011
respiratory system developmentGO:00605411900.011
regulation of vasculature developmentGO:1901342880.011
nucleoside catabolic processGO:00091642060.011
nuclear importGO:0051170950.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
bmp signaling pathwayGO:0030509930.011
detection of biotic stimulusGO:0009595100.011
cardiac chamber morphogenesisGO:0003206930.011
regulation of intracellular transportGO:00323861590.011
ion transmembrane transportGO:00342203610.011
carbohydrate derivative biosynthetic processGO:19011371830.011
ribonucleotide catabolic processGO:00092612080.011
endothelial cell migrationGO:0043542440.011
detection of bacteriumGO:001604570.011
peptidyl amino acid modificationGO:00181933360.011
cerebellum developmentGO:0021549770.011
lateral inhibitionGO:004633110.011
positive regulation of bindingGO:0051099490.011
segmentationGO:0035282930.011
vascular process in circulatory systemGO:0003018620.011
chromatin organizationGO:00063252060.011
microtubule based processGO:00070172360.011
interleukin 8 productionGO:003263740.011
meiotic cell cycle processGO:1903046770.011
peptidyl threonine modificationGO:0018210310.011
hair cycleGO:0042633900.011
heart formationGO:0060914160.011
regulation of cell growthGO:0001558910.011
inorganic ion transmembrane transportGO:00986602340.011
regulation of neural precursor cell proliferationGO:2000177700.011
regulation of anti mullerian hormone signaling pathwayGO:190261210.010
ear morphogenesisGO:00424711180.010
positive regulation of protein catabolic processGO:0045732600.010
response to peptideGO:19016521360.010
regulation of transferase activityGO:00513382630.010
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.010
regulation of alpha beta t cell activationGO:0046634530.010
ribonucleoside triphosphate metabolic processGO:00091992200.010
pituitary gland developmentGO:0021983380.010
positive regulation of kinase activityGO:00336741550.010
endocrine system developmentGO:0035270980.010
glycosyl compound catabolic processGO:19016582060.010
trachea morphogenesisGO:006043980.010
sperm motilityGO:0030317470.010
metencephalon developmentGO:0022037890.010
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041220.010
regulation of protein bindingGO:0043393600.010
regulation of protein serine threonine kinase activityGO:00719001570.010
neuron projection extension involved in neuron projection guidanceGO:1902284140.010
positive regulation of intracellular protein transportGO:0090316420.010
negative regulation of cell proliferationGO:00082852960.010
regulation of epithelial cell migrationGO:0010632350.010
odontogenesisGO:0042476780.010
negative regulation of immune system processGO:00026832090.010
amide transportGO:00428861380.010
skin developmentGO:00435882200.010
heart morphogenesisGO:00030071780.010

Diablo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.019
musculoskeletal system diseaseDOID:1700.019
connective tissue diseaseDOID:6500.019
organ system cancerDOID:005068600.015
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
nervous system diseaseDOID:86300.013
disease of metabolismDOID:001466700.011
inherited metabolic disorderDOID:65500.011
central nervous system diseaseDOID:33100.011
neurodegenerative diseaseDOID:128900.011