Mus musculus

0 known processes

Htra4

HtrA serine peptidase 4

(Aliases: B430206E18Rik)

Htra4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular ketone metabolic processGO:0010565660.094
amine metabolic processGO:0009308450.084
cellular amino acid metabolic processGO:00065201030.080
regulation of cellular amine metabolic processGO:0033238200.075
cellular ketone metabolic processGO:0042180840.070
cellular amine metabolic processGO:0044106440.067
carbohydrate metabolic processGO:00059752300.067
oxidation reduction processGO:00551143420.054
regulation of cellular amino acid metabolic processGO:000652150.052
cation transportGO:00068123990.050
nucleobase containing small molecule metabolic processGO:00550863520.048
g protein coupled receptor signaling pathwayGO:00071862430.044
purine nucleotide metabolic processGO:00061633020.043
positive regulation of cellular amine metabolic processGO:003324050.042
regulation of cell activationGO:00508652890.041
mapk cascadeGO:00001652810.041
negative regulation of molecular functionGO:00440922580.040
forebrain developmentGO:00309003020.039
cellular homeostasisGO:00197252400.039
muscle tissue developmentGO:00605373080.038
regulation of mapk cascadeGO:00434082480.038
cation homeostasisGO:00550802120.038
cytokine productionGO:00018163190.037
regulation of hormone levelsGO:00108172110.037
nucleotide metabolic processGO:00091173320.036
response to organonitrogen compoundGO:00102432460.036
negative regulation of cell proliferationGO:00082852960.036
striated muscle tissue developmentGO:00147062930.035
spermatogenesisGO:00072832840.035
muscle cell differentiationGO:00426922610.035
muscle system processGO:00030121410.035
nucleoside phosphate metabolic processGO:00067533380.034
ribonucleotide metabolic processGO:00092592910.034
metal ion homeostasisGO:00550651890.033
positive regulation of protein modification processGO:00314012990.033
carbohydrate derivative biosynthetic processGO:19011371830.033
cytoplasmic transportGO:00164822340.032
regulation of cytokine productionGO:00018172660.032
regulation of kinase activityGO:00435492490.031
negative regulation of protein metabolic processGO:00512482820.031
nitrogen compound transportGO:00717052710.031
positive regulation of cellular amino acid metabolic processGO:004576430.031
regulation of lymphocyte activationGO:00512492400.030
small gtpase mediated signal transductionGO:0007264970.030
ion transmembrane transportGO:00342203610.029
macromolecule catabolic processGO:00090572810.029
cellular chemical homeostasisGO:00550822150.029
cellular lipid metabolic processGO:00442553230.029
purine containing compound metabolic processGO:00725213110.028
male gamete generationGO:00482322850.028
purine ribonucleotide metabolic processGO:00091502900.028
leukocyte differentiationGO:00025213420.028
regulation of secretionGO:00510462740.028
positive regulation of protein phosphorylationGO:00019342420.027
skeletal system developmentGO:00015013560.027
regulation of organelle organizationGO:00330432890.027
protein modification by small protein conjugation or removalGO:00706472070.027
small molecule biosynthetic processGO:00442831320.027
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.027
regulation of system processGO:00440572000.027
anion transportGO:00068201770.027
cell adhesionGO:00071553290.026
negative regulation of intracellular signal transductionGO:19025321670.026
cellular metal ion homeostasisGO:00068751510.026
t cell activationGO:00421102890.026
regulation of cell cycleGO:00517262810.026
regulation of protein localizationGO:00328802310.025
protein processingGO:00164851630.025
negative regulation of phosphorus metabolic processGO:00105631840.025
positive regulation of nervous system developmentGO:00519622210.025
inflammatory responseGO:00069542440.025
intracellular protein transportGO:00068862040.025
cation transmembrane transportGO:00986552660.025
cellular ion homeostasisGO:00068731650.025
negative regulation of cellular protein metabolic processGO:00322692470.024
cellular carbohydrate metabolic processGO:00442621190.024
response to molecule of bacterial originGO:00022371430.024
regulation of establishment of protein localizationGO:00702011810.024
cellular nitrogen compound catabolic processGO:00442702800.024
mitotic cell cycleGO:00002781950.024
ras protein signal transductionGO:0007265770.024
protein maturationGO:00516041760.024
transmembrane transportGO:00550854120.024
apoptotic signaling pathwayGO:00971903060.024
germ cell developmentGO:00072811850.024
organic cyclic compound catabolic processGO:19013612950.023
organic hydroxy compound metabolic processGO:19016152030.023
circulatory system processGO:00030131970.023
ribose phosphate metabolic processGO:00196932910.023
nucleoside metabolic processGO:00091162460.023
cellular response to lipidGO:00713961450.023
heterocycle catabolic processGO:00467002800.023
ossificationGO:00015032160.023
aromatic compound catabolic processGO:00194392860.022
generation of precursor metabolites and energyGO:00060911030.022
cellular macromolecule catabolic processGO:00442652060.022
organophosphate biosynthetic processGO:00904071220.022
peptidyl amino acid modificationGO:00181933360.022
skeletal muscle organ developmentGO:00605381630.022
meiotic nuclear divisionGO:00071261150.022
regulation of protein kinase activityGO:00458592320.022
anatomical structure homeostasisGO:00602491450.022
neuronal action potentialGO:0019228540.021
transmission of nerve impulseGO:0019226760.021
maintenance of locationGO:0051235890.021
cellular calcium ion homeostasisGO:00068741190.021
connective tissue developmentGO:00614481790.021
hormone metabolic processGO:0042445860.021
angiogenesisGO:00015252010.021
regulation of secretion by cellGO:19035302490.021
response to extracellular stimulusGO:00099911270.021
regulation of defense responseGO:00313472330.021
leukocyte proliferationGO:00706611720.021
sensory perceptionGO:00076002450.020
nucleoside triphosphate metabolic processGO:00091412300.020
actin cytoskeleton organizationGO:00300362200.020
positive regulation of hydrolase activityGO:00513451480.020
negative regulation of cellular component organizationGO:00511291940.020
regulation of neuron differentiationGO:00456642810.020
immune effector processGO:00022523210.020
protein localization to organelleGO:00333651850.020
organonitrogen compound biosynthetic processGO:19015661920.020
hexose metabolic processGO:0019318980.020
purine nucleotide catabolic processGO:00061952110.020
ribonucleotide catabolic processGO:00092612080.020
muscle contractionGO:00069361010.020
cardiac muscle tissue developmentGO:00487381300.020
negative regulation of phosphate metabolic processGO:00459361840.020
synaptic transmissionGO:00072683290.020
locomotory behaviorGO:00076261950.020
regulation of leukocyte proliferationGO:00706631210.020
positive regulation of cell activationGO:00508671580.020
regulation of transferase activityGO:00513382630.019
monosaccharide metabolic processGO:00059961060.019
cellular response to organonitrogen compoundGO:00714171450.019
regulation of membrane potentialGO:00423911920.019
monocarboxylic acid metabolic processGO:00327871910.019
regulation of anatomical structure sizeGO:00900661780.019
sequestering of calcium ionGO:0051208180.019
sequestering of metal ionGO:0051238190.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
response to organic cyclic compoundGO:00140701980.019
response to lipopolysaccharideGO:00324961280.019
carbohydrate derivative catabolic processGO:19011362310.019
protein catabolic processGO:00301632210.019
innate immune responseGO:00450871570.019
amide transportGO:00428861380.019
ribonucleoside metabolic processGO:00091192450.019
muscle cell developmentGO:00550011330.019
positive regulation of cytokine productionGO:00018191740.019
energy derivation by oxidation of organic compoundsGO:0015980770.018
peptidyl tyrosine phosphorylationGO:00181081430.018
cellular response to hormone stimulusGO:00328701500.018
myeloid cell differentiationGO:00300992330.018
positive regulation of secretionGO:00510471300.018
blood circulationGO:00080151950.018
regulation of cellular carbohydrate metabolic processGO:0010675750.018
positive regulation of mapk cascadeGO:00434101700.018
fat cell differentiationGO:00454441600.018
glycoprotein metabolic processGO:00091001160.018
response to growth factorGO:00708481980.018
gland developmentGO:00487323300.018
regulation of response to woundingGO:19030341890.018
positive regulation of secretion by cellGO:19035321140.018
protein modification by small protein conjugationGO:00324461870.018
protein secretionGO:00093061110.018
lymphocyte differentiationGO:00300982420.018
regulation of hydrolase activityGO:00513362460.018
regulation of body fluid levelsGO:00508781620.018
glucose homeostasisGO:00425931280.018
multicellular organismal signalingGO:0035637910.018
urogenital system developmentGO:00016552610.018
regulation of cellular component biogenesisGO:00440871810.018
camera type eye developmentGO:00430102660.018
regulation of protein transportGO:00512231630.018
divalent metal ion transportGO:00708381720.018
membrane organizationGO:00610242450.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.017
rho protein signal transductionGO:0007266320.017
renal system developmentGO:00720012250.017
organelle fissionGO:00482851700.017
response to peptide hormoneGO:00434341270.017
glycosyl compound metabolic processGO:19016572460.017
regulation of apoptotic signaling pathwayGO:20012331970.017
regulation of carbohydrate metabolic processGO:0006109750.017
purine ribonucleoside metabolic processGO:00461282410.017
organic anion transportGO:00157111370.017
nucleoside phosphate catabolic processGO:19012922220.017
inorganic ion transmembrane transportGO:00986602340.017
purine ribonucleotide catabolic processGO:00091542080.017
positive regulation of protein kinase activityGO:00458601440.017
regulation of purine nucleotide metabolic processGO:19005421690.017
positive regulation of apoptotic processGO:00430652170.017
ribonucleoside triphosphate metabolic processGO:00091992200.017
glucose metabolic processGO:0006006920.017
regulation of ion transportGO:00432692150.017
microtubule based processGO:00070172360.017
regulation of cell motilityGO:20001452360.017
response to peptideGO:19016521360.017
organonitrogen compound catabolic processGO:19015652640.017
cellular response to biotic stimulusGO:0071216920.017
purine nucleoside triphosphate catabolic processGO:00091462030.016
nucleoside catabolic processGO:00091642060.016
response to nutrient levelsGO:00316671090.016
negative regulation of phosphorylationGO:00423261660.016
lymphocyte proliferationGO:00466511640.016
positive regulation of cell developmentGO:00107202370.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.016
negative regulation of nervous system developmentGO:00519611560.016
dna metabolic processGO:00062593030.016
protein targetingGO:00066051430.016
regulation of lymphocyte proliferationGO:00506701170.016
telencephalon developmentGO:00215371860.016
regulation of nucleotide metabolic processGO:00061401690.016
multicellular organismal homeostasisGO:00488711640.016
ribonucleoside triphosphate catabolic processGO:00092031990.016
nucleoside triphosphate catabolic processGO:00091432050.016
blood vessel morphogenesisGO:00485142850.016
nucleocytoplasmic transportGO:00069131390.016
inorganic cation transmembrane transportGO:00986622070.016
regulation of protein serine threonine kinase activityGO:00719001570.016
carbohydrate homeostasisGO:00335001280.016
regulation of t cell activationGO:00508631700.016
nuclear divisionGO:00002801580.016
regulation of vasculature developmentGO:1901342880.016
polysaccharide metabolic processGO:0005976390.016
positive regulation of transferase activityGO:00513471670.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
positive regulation of purine nucleotide metabolic processGO:19005441140.015
microtubule cytoskeleton organizationGO:00002261570.015
regulation of cellular catabolic processGO:00313292420.015
positive regulation of lymphocyte activationGO:00512511400.015
negative regulation of protein modification processGO:00314001630.015
positive regulation of cell deathGO:00109422240.015
mitotic cell cycle processGO:19030471590.015
purine ribonucleoside triphosphate catabolic processGO:00092071990.015
purine containing compound catabolic processGO:00725232130.015
b cell activationGO:00421131610.015
negative regulation of immune system processGO:00026832090.015
regulation of intracellular transportGO:00323861590.015
regulation of cell migrationGO:00303342190.015
homeostasis of number of cellsGO:00488722100.015
single organism cell adhesionGO:00986021560.015
meiotic cell cycleGO:00513211220.015
ribose phosphate biosynthetic processGO:0046390590.015
response to insulinGO:00328681000.015
morphogenesis of embryonic epitheliumGO:00163311590.015
cellular protein complex assemblyGO:00436231160.015
ribonucleoside catabolic processGO:00424542060.015
positive regulation of defense responseGO:00313491240.015
reactive oxygen species metabolic processGO:0072593840.015
cellular protein catabolic processGO:00442571550.015
positive regulation of kinase activityGO:00336741550.015
carbohydrate biosynthetic processGO:0016051740.015
myeloid leukocyte differentiationGO:00025731190.015
cellular response to growth factor stimulusGO:00713631970.015
developmental maturationGO:00217001930.015
carboxylic acid transportGO:00469421000.015
regulation of interleukin 8 productionGO:003267730.014
nucleoside phosphate biosynthetic processGO:1901293790.014
protein ubiquitinationGO:00165671710.014
purine ribonucleoside catabolic processGO:00461302050.014
lipid biosynthetic processGO:00086101790.014
wnt signaling pathwayGO:00160551880.014
axonogenesisGO:00074092740.014
actin filament organizationGO:00070151130.014
endocytosisGO:00068971680.014
glycosyl compound catabolic processGO:19016582060.014
activation of immune responseGO:00022531380.014
protein import into nucleusGO:0006606950.014
purine nucleoside metabolic processGO:00422782410.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
sulfur compound metabolic processGO:00067901000.014
digestive system developmentGO:00551232000.014
nuclear transportGO:00511691390.014
negative regulation of cell developmentGO:00107211690.014
cell activation involved in immune responseGO:00022631260.014
calcium ion homeostasisGO:00550741270.014
ubiquitin dependent protein catabolic processGO:00065111290.014
regulation of cellular response to stressGO:00801351590.014
respiratory system developmentGO:00605411900.014
peptidyl tyrosine modificationGO:00182121450.014
spermatid differentiationGO:00485151150.014
divalent inorganic cation homeostasisGO:00725071380.014
organophosphate catabolic processGO:00464342320.014
divalent inorganic cation transportGO:00725111780.014
ear developmentGO:00435832000.014
lateral inhibitionGO:004633110.014
t cell differentiationGO:00302171740.014
positive regulation of nucleotide metabolic processGO:00459811140.013
cell maturationGO:00484691270.013
regulation of cell cycle processGO:00105641600.013
glycoprotein biosynthetic processGO:0009101890.013
tissue homeostasisGO:00018941150.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
protein localization to nucleusGO:00345041210.013
epithelial tube morphogenesisGO:00605623030.013
action potentialGO:0001508780.013
kidney developmentGO:00018222130.013
oocyte axis specificationGO:000730920.013
midgut developmentGO:000749440.013
cellular response to cytokine stimulusGO:00713451890.013
modification dependent protein catabolic processGO:00199411330.013
cellular response to molecule of bacterial originGO:0071219830.013
learning or memoryGO:00076111480.013
chemotaxisGO:00069352470.013
cellular polysaccharide metabolic processGO:0044264380.013
cognitionGO:00508901490.013
response to acid chemicalGO:00011011110.013
regulation of tube sizeGO:0035150570.013
glucan metabolic processGO:0044042320.013
purine nucleoside catabolic processGO:00061522050.013
organic acid transportGO:00158491010.013
defense response to other organismGO:00985421970.013
posttranscriptional regulation of gene expressionGO:00106081550.013
regulation of cell projection organizationGO:00313442060.013
respiratory tube developmentGO:00303231670.013
organelle localizationGO:00516401790.013
nucleotide catabolic processGO:00091662170.013
neural tube developmentGO:00219151600.013
myotube differentiationGO:00149021050.013
cell fate commitmentGO:00451652100.013
positive regulation of programmed cell deathGO:00430682180.013
peptide transportGO:00158331330.013
positive regulation of cellular catabolic processGO:00313311480.013
regulation of leukocyte differentiationGO:19021051590.013
negative regulation of protein maturationGO:1903318790.013
modification dependent macromolecule catabolic processGO:00436321330.013
reactive nitrogen species metabolic processGO:200105700.013
purine nucleotide biosynthetic processGO:0006164650.013
negative regulation of cellular amine metabolic processGO:003323910.013
carboxylic acid biosynthetic processGO:0046394860.013
regulation of cell adhesionGO:00301551540.013
cell divisionGO:00513011200.013
cellular response to insulin stimulusGO:0032869780.013
heart morphogenesisGO:00030071780.013
organelle assemblyGO:00709251770.012
nucleotide biosynthetic processGO:0009165780.012
hormone secretionGO:00468791280.012
negative regulation of cell cycleGO:00457861230.012
positive regulation of organelle organizationGO:00106381280.012
rna interferenceGO:001624620.012
tissue remodelingGO:00487711020.012
appendage developmentGO:00487361660.012
morphogenesis of a branching epitheliumGO:00611381930.012
tube formationGO:00351481400.012
regulation of ossificationGO:00302781120.012
regulation of protein processingGO:0070613960.012
digestive tract developmentGO:00485651900.012
regulation of inflammatory responseGO:00507271470.012
regulation of proteolysisGO:00301621640.012
interleukin 8 productionGO:003263740.012
extracellular structure organizationGO:00430621480.012
regulation of organ morphogenesisGO:20000271440.012
cellular response to starvationGO:0009267570.012
peptide secretionGO:00027901140.012
neural precursor cell proliferationGO:00613511210.012
response to oxygen levelsGO:0070482620.012
regulation of peptidyl tyrosine phosphorylationGO:0050730930.012
multi multicellular organism processGO:00447061090.012
lipid transportGO:0006869980.012
erk1 and erk2 cascadeGO:0070371770.012
regulation of protein maturationGO:1903317960.012
single organism nuclear importGO:1902593950.012
establishment of protein localization to organelleGO:00725941180.012
cytokine mediated signaling pathwayGO:00192211150.012
cell substrate adhesionGO:00315891300.012
cartilage developmentGO:00512161400.012
synapse organizationGO:00508081250.012
negative regulation of apoptotic signaling pathwayGO:20012341040.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
regulation of map kinase activityGO:00434051200.012
rhythmic processGO:00485111740.012
oocyte constructionGO:000730820.012
spermatid developmentGO:00072861080.012
cellular response to lipopolysaccharideGO:0071222770.012
organic acid biosynthetic processGO:0016053860.012
lung developmentGO:00303241640.012
endomembrane system organizationGO:00102561470.012
regulation of glucose metabolic processGO:0010906600.012
positive regulation of growthGO:00459271040.012
organ growthGO:00352651170.012
stem cell differentiationGO:00488632680.012
leukocyte migrationGO:00509001240.012
epithelial cell proliferationGO:00506731740.011
striated muscle cell developmentGO:00550021250.011
cytokine secretionGO:0050663720.011
regulation of lipid metabolic processGO:00192161180.011
regulation of homeostatic processGO:00328441820.011
cell type specific apoptotic processGO:00972852680.011
sensory organ morphogenesisGO:00905962420.011
regulation of vesicle mediated transportGO:00606271390.011
multicellular organism growthGO:00352641610.011
regulation of t cell proliferationGO:0042129920.011
purine containing compound biosynthetic processGO:0072522700.011
embryonic organ morphogenesisGO:00485622760.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
monosaccharide transportGO:0015749580.011
regulation of metal ion transportGO:00109591060.011
cellular response to peptideGO:1901653920.011
regulation of protein secretionGO:0050708820.011
immune response regulating signaling pathwayGO:00027641250.011
regulation of angiogenesisGO:0045765810.011
organic hydroxy compound transportGO:0015850930.011
alcohol metabolic processGO:00060661160.011
cellular response to peptide hormone stimulusGO:0071375920.011
purine ribonucleotide biosynthetic processGO:0009152590.011
epithelial cell developmentGO:00020641590.011
exocytosisGO:00068871210.011
immune response activating signal transductionGO:00027571160.011
regulation of fat cell differentiationGO:0045598810.011
branching morphogenesis of an epithelial tubeGO:00487541590.011
t cell proliferationGO:00420981200.011
calcium ion transportGO:00068161590.011
negative regulation of homeostatic processGO:0032845710.011
energy reserve metabolic processGO:0006112390.011
cellular glucan metabolic processGO:0006073320.011
mesodermal cell migrationGO:000807840.011
cofactor metabolic processGO:0051186800.011
skeletal system morphogenesisGO:00487052030.011
positive regulation of immune effector processGO:00026991070.011
morphogenesis of a branching structureGO:00017632030.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.011
amino acid transportGO:0006865610.011
regulation of blood pressureGO:0008217930.011
protein importGO:00170381010.011
interleukin 8 secretionGO:007260630.011
regulation of mitotic cell cycleGO:00073461260.011
cellular modified amino acid metabolic processGO:0006575630.011
skin developmentGO:00435882200.011
limb developmentGO:00601731660.011
ribonucleotide biosynthetic processGO:0009260590.011
carbohydrate transportGO:0008643620.011
nuclear importGO:0051170950.011
regulation of cytoplasmic transportGO:19036491120.011
regulation of interleukin 8 secretionGO:200048220.011
positive regulation of interleukin 8 productionGO:003275720.010
adaptive immune responseGO:00022501550.010
leukocyte activation involved in immune responseGO:00023661260.010
cytosolic calcium ion homeostasisGO:0051480700.010
response to hypoxiaGO:0001666580.010
development of primary sexual characteristicsGO:00451371430.010
fertilizationGO:00095661270.010
negative regulation of protein phosphorylationGO:00019331260.010
cardiocyte differentiationGO:0035051870.010
negative regulation of growthGO:0045926990.010
lymphocyte mediated immunityGO:00024491390.010
cellular response to extracellular stimulusGO:0031668810.010
cellular response to organic cyclic compoundGO:0071407870.010
negative regulation of mapk cascadeGO:0043409650.010
compound eye developmentGO:004874910.010
mature dendritic cell differentiationGO:009702930.010
positive regulation of protein transportGO:0051222930.010
nucleoside monophosphate metabolic processGO:0009123850.010
positive regulation of reactive oxygen species metabolic processGO:2000379110.010
coenzyme metabolic processGO:0006732520.010
positive regulation of phospholipase activityGO:001051830.010
embryonic limb morphogenesisGO:00303261260.010
epithelial tube formationGO:00721751300.010
stem cell developmentGO:00488642190.010
placenta developmentGO:00018901400.010
glial cell differentiationGO:00100011310.010
regulation of cytoskeleton organizationGO:00514931220.010

Htra4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.029
disease of anatomical entityDOID:700.029
musculoskeletal system diseaseDOID:1700.023
connective tissue diseaseDOID:6500.020
sensory system diseaseDOID:005015500.018
disease of metabolismDOID:001466700.014
eye and adnexa diseaseDOID:149200.013
eye diseaseDOID:561400.013
central nervous system diseaseDOID:33100.011
cardiovascular system diseaseDOID:128700.011
disease of cellular proliferationDOID:1456600.010
inherited metabolic disorderDOID:65500.010