Mus musculus

66 known processes

Htra2

HtrA serine peptidase 2

(Aliases: AI481710,Omi,mnd2,Prss25)

Htra2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
amine metabolic processGO:0009308450.055
cellular amino acid metabolic processGO:00065201030.054
negative regulation of molecular functionGO:00440922580.046
nucleobase containing small molecule metabolic processGO:00550863520.044
cellular response to dna damage stimulusGO:00069742070.041
Human
regulation of cellular amine metabolic processGO:0033238200.040
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.038
cellular amine metabolic processGO:0044106440.037
positive regulation of cell deathGO:00109422240.037
positive regulation of protein modification processGO:00314012990.037
nitrogen compound transportGO:00717052710.036
protein ubiquitinationGO:00165671710.034
regulation of cellular amino acid metabolic processGO:000652150.033
negative regulation of cellular protein metabolic processGO:00322692470.032
positive regulation of cellular amine metabolic processGO:003324050.031
protein modification by small protein conjugationGO:00324461870.031
cell type specific apoptotic processGO:00972852680.030
cellular ketone metabolic processGO:0042180840.029
negative regulation of phosphorylationGO:00423261660.029
positive regulation of cellular amino acid metabolic processGO:004576430.028
macromolecule catabolic processGO:00090572810.028
Human
gland developmentGO:00487323300.028
reactive oxygen species metabolic processGO:0072593840.028
nuclear divisionGO:00002801580.028
ion transmembrane transportGO:00342203610.027
translationGO:0006412930.027
carbohydrate derivative biosynthetic processGO:19011371830.027
protein processingGO:00164851630.027
transmembrane transportGO:00550854120.027
inflammatory responseGO:00069542440.025
nucleotide metabolic processGO:00091173320.025
regulation of protein complex assemblyGO:0043254830.025
negative regulation of protein metabolic processGO:00512482820.025
mitotic cell cycle processGO:19030471590.025
cellular response to cytokine stimulusGO:00713451890.025
Human
cation transportGO:00068123990.025
response to organic cyclic compoundGO:00140701980.025
positive regulation of apoptotic processGO:00430652170.025
placenta developmentGO:00018901400.025
cellular homeostasisGO:00197252400.024
organelle fissionGO:00482851700.024
mitotic cell cycleGO:00002781950.024
nucleoside phosphate metabolic processGO:00067533380.024
activation of immune responseGO:00022531380.024
neuron deathGO:00709971540.023
regulation of proteolysisGO:00301621640.022
Human Fly
protein maturationGO:00516041760.022
membrane organizationGO:00610242450.022
cytoplasmic transportGO:00164822340.022
negative regulation of phosphorus metabolic processGO:00105631840.022
organonitrogen compound biosynthetic processGO:19015661920.022
cell adhesionGO:00071553290.021
dna metabolic processGO:00062593030.021
spermatogenesisGO:00072832840.021
Fly
defense response to bacteriumGO:00427421190.021
regulation of protein kinase activityGO:00458592320.020
regulation of reactive oxygen species metabolic processGO:2000377400.020
response to acid chemicalGO:00011011110.020
Human
cellular response to hormone stimulusGO:00328701500.020
negative regulation of phosphate metabolic processGO:00459361840.019
t cell activationGO:00421102890.019
immune effector processGO:00022523210.019
leukocyte proliferationGO:00706611720.019
cytokine productionGO:00018163190.019
meiotic nuclear divisionGO:00071261150.018
mitochondrion organizationGO:00070051340.018
regulation of cellular ketone metabolic processGO:0010565660.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.018
Mouse
necroptotic processGO:0070266210.018
negative regulation of necroptotic processGO:006054690.017
regulation of cell cycleGO:00517262810.017
positive regulation of programmed cell deathGO:00430682180.017
positive regulation of mapk cascadeGO:00434101700.017
regulation of transferase activityGO:00513382630.017
positive regulation of protein phosphorylationGO:00019342420.017
regulation of lymphocyte activationGO:00512492400.017
protein localization to organelleGO:00333651850.016
negative regulation of cell proliferationGO:00082852960.016
regulation of necroptotic processGO:0060544100.016
regulation of cellular response to stressGO:00801351590.016
negative regulation of intracellular signal transductionGO:19025321670.016
leukocyte differentiationGO:00025213420.016
defense response to other organismGO:00985421970.016
innate immune responseGO:00450871570.016
purine ribonucleoside metabolic processGO:00461282410.016
neuron apoptotic processGO:00514021420.015
skeletal system developmentGO:00015013560.015
regulation of apoptotic signaling pathwayGO:20012331970.015
Human
regulation of cell activationGO:00508652890.015
regulation of kinase activityGO:00435492490.015
wnt signaling pathwayGO:00160551880.015
response to oxidative stressGO:00069791230.015
lymphocyte proliferationGO:00466511640.015
sensory perceptionGO:00076002450.015
positive regulation of lymphocyte activationGO:00512511400.015
cation transmembrane transportGO:00986552660.015
b cell activationGO:00421131610.014
organophosphate biosynthetic processGO:00904071220.014
male gamete generationGO:00482322850.014
Fly
cellular response to lipidGO:00713961450.014
Human
regulation of homeostatic processGO:00328441820.014
meiotic cell cycleGO:00513211220.014
response to organonitrogen compoundGO:00102432460.014
fertilizationGO:00095661270.014
epithelial tube morphogenesisGO:00605623030.014
peptidyl amino acid modificationGO:00181933360.014
skeletal muscle organ developmentGO:00605381630.014
carbohydrate metabolic processGO:00059752300.013
apoptotic signaling pathwayGO:00971903060.013
methylationGO:00322591340.013
cellular response to biotic stimulusGO:0071216920.013
regulation of mapk cascadeGO:00434082480.013
response to steroid hormoneGO:0048545560.013
multi organism behaviorGO:0051705620.013
ribonucleotide metabolic processGO:00092592910.013
regulation of response to woundingGO:19030341890.013
aromatic compound catabolic processGO:00194392860.013
regulation of cell migrationGO:00303342190.013
negative regulation of protein phosphorylationGO:00019331260.013
cellular response to acid chemicalGO:0071229680.013
Human
regulation of hydrolase activityGO:00513362460.013
Human Fly
negative regulation of immune system processGO:00026832090.013
regulation of wnt signaling pathwayGO:00301111230.013
cellular response to organic cyclic compoundGO:0071407870.013
intraspecies interaction between organismsGO:0051703210.013
regulation of body fluid levelsGO:00508781620.013
modification dependent macromolecule catabolic processGO:00436321330.013
positive regulation of transferase activityGO:00513471670.013
striated muscle tissue developmentGO:00147062930.013
myotube differentiationGO:00149021050.013
social behaviorGO:0035176210.012
t cell proliferationGO:00420981200.012
necrotic cell deathGO:0070265300.012
regulation of membrane potentialGO:00423911920.012
leukocyte migrationGO:00509001240.012
protein catabolic processGO:00301632210.012
Human
response to radiationGO:00093141650.012
multicellular organismal homeostasisGO:00488711640.012
regulation of hormone levelsGO:00108172110.012
posttranscriptional regulation of gene expressionGO:00106081550.012
nuclear transportGO:00511691390.012
oxidation reduction processGO:00551143420.012
regulation of protein processingGO:0070613960.012
regulation of neuron deathGO:19012141340.012
regulation of t cell activationGO:00508631700.012
regulation of neuron differentiationGO:00456642810.012
cellular chemical homeostasisGO:00550822150.012
dna repairGO:00062811070.012
cellular nitrogen compound catabolic processGO:00442702800.012
immune response activating signal transductionGO:00027571160.011
negative regulation of protein modification processGO:00314001630.011
response to lipopolysaccharideGO:00324961280.011
regulation of cell cycle phase transitionGO:1901987770.011
organelle localizationGO:00516401790.011
canonical wnt signaling pathwayGO:00600701300.011
regulation of mitotic cell cycle phase transitionGO:1901990730.011
sensory organ morphogenesisGO:00905962420.011
regulation of ion transportGO:00432692150.011
divalent inorganic cation transportGO:00725111780.011
epithelial cell proliferationGO:00506731740.011
regulation of defense responseGO:00313472330.011
lymphocyte differentiationGO:00300982420.011
organic hydroxy compound metabolic processGO:19016152030.011
small gtpase mediated signal transductionGO:0007264970.011
cellular protein catabolic processGO:00442571550.011
Human
regulation of inflammatory responseGO:00507271470.011
telencephalon developmentGO:00215371860.011
inorganic cation transmembrane transportGO:00986622070.011
protein polyubiquitinationGO:0000209330.011
cytokine mediated signaling pathwayGO:00192211150.011
peptide transportGO:00158331330.011
muscle cell differentiationGO:00426922610.011
regulation of cell projection organizationGO:00313442060.011
regulation of cell cycle processGO:00105641600.011
carbohydrate derivative catabolic processGO:19011362310.011
response to light stimulusGO:00094161350.011
negative regulation of transferase activityGO:0051348850.011
positive regulation of cell activationGO:00508671580.011
positive regulation of protein kinase activityGO:00458601440.011
regulation of neuron apoptotic processGO:00435231220.011
stem cell differentiationGO:00488632680.011
regulation of cellular component biogenesisGO:00440871810.011
detection of stimulusGO:0051606840.011
glycoprotein metabolic processGO:00091001160.011
negative regulation of neuron apoptotic processGO:0043524920.011
regulation of cell motilityGO:20001452360.010
regulation of organelle organizationGO:00330432890.010
proteolysis involved in cellular protein catabolic processGO:00516031470.010
sequestering of calcium ionGO:0051208180.010
nucleotide catabolic processGO:00091662170.010
divalent metal ion transportGO:00708381720.010
regulation of protein serine threonine kinase activityGO:00719001570.010
cell divisionGO:00513011200.010
cellular response to growth factor stimulusGO:00713631970.010
Human Mouse
purine containing compound metabolic processGO:00725213110.010
connective tissue developmentGO:00614481790.010
regulation of protein localizationGO:00328802310.010
protein modification by small protein conjugation or removalGO:00706472070.010
germ cell developmentGO:00072811850.010

Htra2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
Human
nervous system diseaseDOID:86300.035
Human
central nervous system diseaseDOID:33100.014
Human
neurodegenerative diseaseDOID:128900.010
Human