Mus musculus

102 known processes

Ddx5

DEAD (Asp-Glu-Ala-Asp) box polypeptide 5

(Aliases: p68,HUMP68,2600009A06Rik,MGC118083,G17P1,Hlr1)

Ddx5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna splicing via transesterification reactionsGO:0000375430.960
Human Fly
rna splicingGO:0008380540.928
Human Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.925
Human Fly
regulation of mrna processingGO:0050684410.910
Human Fly
mrna splicing via spliceosomeGO:0000398430.820
Human Fly
mrna metabolic processGO:0016071840.713
Human Yeast Fly
regulation of mrna splicing via spliceosomeGO:0048024320.689
Human Fly
regulation of rna splicingGO:0043484370.686
Human Fly
spermatogenesisGO:00072832840.682
mrna processingGO:0006397630.681
Human Fly
regulation of alternative mrna splicing via spliceosomeGO:000038180.678
Human Fly
germ cell developmentGO:00072811850.656
spermatid differentiationGO:00485151150.655
3 utr mediated mrna stabilizationGO:007093520.619
ribonucleoprotein complex subunit organizationGO:0071826280.619
Yeast
nuclear divisionGO:00002801580.581
mitotic cell cycleGO:00002781950.575
rna processingGO:00063961050.526
Human Yeast Fly
regulation of translationGO:0006417710.508
meiotic cell cycle processGO:1903046770.406
cellular macromolecule catabolic processGO:00442652060.406
Yeast
meiotic nuclear divisionGO:00071261150.375
organelle fissionGO:00482851700.353
multicellular organism growthGO:00352641610.350
male gamete generationGO:00482322850.349
mitotic nuclear divisionGO:0007067480.326
morphogenesis of embryonic epitheliumGO:00163311590.322
gonad developmentGO:00084061410.321
cell divisionGO:00513011200.314
regulation of cell cycleGO:00517262810.299
translationGO:0006412930.287
spermatid developmentGO:00072861080.286
alternative mrna splicing via spliceosomeGO:0000380120.267
Human Fly
translational initiationGO:0006413240.260
cellular response to dna damage stimulusGO:00069742070.196
Human
positive regulation of programmed cell deathGO:00430682180.186
meiotic cell cycleGO:00513211220.159
receptor biosynthetic processGO:003280030.157
genitalia developmentGO:0048806370.148
modification dependent macromolecule catabolic processGO:00436321330.147
Yeast
stem cell developmentGO:00488642190.141
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018410.132
Yeast
homeostasis of number of cellsGO:00488722100.131
negative regulation of translationGO:0017148220.130
regulation of muscle tissue developmentGO:1901861970.125
regulation of mrna stabilityGO:0043488230.124
establishment of organelle localizationGO:00516561220.123
negative regulation of mrna processingGO:0050686120.121
regionalizationGO:00030023370.120
regulation of mrna metabolic processGO:1903311430.116
Human Fly
heterocycle catabolic processGO:00467002800.115
Yeast
t cell activationGO:00421102890.110
apoptotic signaling pathwayGO:00971903060.109
Human
protein alkylationGO:0008213810.107
oogenesisGO:0048477560.104
fertilizationGO:00095661270.102
axonogenesisGO:00074092740.100
gene silencingGO:0016458380.092
Fly
male anatomical structure morphogenesisGO:009059840.091
posttranscriptional regulation of gene expressionGO:00106081550.091
Fly
skeletal muscle cell differentiationGO:0035914660.089
epithelial to mesenchymal transitionGO:0001837470.082
cellular amine metabolic processGO:0044106440.082
inflammatory responseGO:00069542440.081
positive regulation of receptor biosynthetic processGO:001087010.081
female sex differentiationGO:0046660840.081
cell adhesionGO:00071553290.080
chromosome segregationGO:0007059480.079
circadian rhythmGO:00076231140.079
positive regulation of intracellular estrogen receptor signaling pathwayGO:003314840.078
Human
oocyte anterior posterior axis specificationGO:000731420.074
negative regulation of mrna splicing via spliceosomeGO:0048025120.074
negative regulation of cell proliferationGO:00082852960.073
lung developmentGO:00303241640.073
development of primary female sexual characteristicsGO:0046545730.071
hindbrain developmentGO:00309021280.068
mesenchyme developmentGO:00604851520.068
positive regulation of proteolysisGO:0045862850.066
muscle tissue developmentGO:00605373080.066
maternal determination of anterior posterior axis embryoGO:000835820.065
developmental growth involved in morphogenesisGO:00605601380.065
digestive tract developmentGO:00485651900.064
negative regulation of cellular protein metabolic processGO:00322692470.063
rna interferenceGO:001624620.062
Fly
glycosyl compound metabolic processGO:19016572460.062
Yeast
nitrogen compound transportGO:00717052710.060
stem cell differentiationGO:00488632680.060
regulation of mitotic cell cycleGO:00073461260.060
oocyte constructionGO:000730820.059
multicellular organismal reproductive behaviorGO:0033057230.058
striated muscle tissue developmentGO:00147062930.058
regulation of organelle organizationGO:00330432890.057
mrna catabolic processGO:0006402220.057
Yeast
development of primary sexual characteristicsGO:00451371430.057
molting cycleGO:0042303900.056
mitotic cell cycle processGO:19030471590.055
positive regulation of growthGO:00459271040.055
organic cyclic compound catabolic processGO:19013612950.054
Yeast
male meiosisGO:0007140370.053
organelle assemblyGO:00709251770.053
neuron projection extensionGO:1990138640.051
digestive tract morphogenesisGO:00485461470.051
nucleoside catabolic processGO:00091642060.051
Yeast
purine nucleoside triphosphate catabolic processGO:00091462030.050
Yeast
regulation of synaptic growth at neuromuscular junctionGO:000858240.049
intracellular mrna localizationGO:000829840.048
neurotransmitter transportGO:0006836760.048
regulation of nuclear divisionGO:0051783560.048
female gamete generationGO:0007292740.048
macromolecule catabolic processGO:00090572810.047
Yeast
negative regulation of protein metabolic processGO:00512482820.046
ossificationGO:00015032160.045
skin developmentGO:00435882200.045
regulation of cell cycle processGO:00105641600.044
establishment or maintenance of cell polarityGO:0007163860.044
organelle localizationGO:00516401790.044
dna damage checkpointGO:0000077260.043
mesenchymal cell developmentGO:0014031930.043
cellular nitrogen compound catabolic processGO:00442702800.043
Yeast
female gonad developmentGO:0008585710.041
spliceosomal complex disassemblyGO:000039010.041
protein modification by small protein conjugationGO:00324461870.041
oocyte developmentGO:0048599330.040
regulation of epidermis developmentGO:0045682330.040
cell growthGO:00160491300.040
dephosphorylationGO:00163111290.040
neural crest cell differentiationGO:0014033540.039
stem cell maintenanceGO:00198271300.038
respiratory tube developmentGO:00303231670.038
myosin filament organizationGO:003103330.037
regulation of cell divisionGO:0051302760.037
heart contractionGO:0060047930.036
negative regulation of mrna metabolic processGO:1903312130.036
positive regulation of apoptotic processGO:00430652170.036
gene silencing by rnaGO:0031047190.036
Fly
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.035
purine containing compound metabolic processGO:00725213110.034
Yeast
rna localizationGO:0006403230.034
positive regulation of cell deathGO:00109422240.034
myeloid leukocyte differentiationGO:00025731190.033
metencephalon developmentGO:0022037890.032
gland developmentGO:00487323300.032
protein catabolic processGO:00301632210.032
respiratory system developmentGO:00605411900.032
regulation of epithelial cell proliferationGO:00506781410.031
neurotransmitter secretionGO:0007269620.031
purine ribonucleoside monophosphate metabolic processGO:0009167800.030
Yeast
nucleotide metabolic processGO:00091173320.030
Yeast
localization within membraneGO:005166840.030
metaphase plate congressionGO:005131020.030
regulation of g1 s transition of mitotic cell cycleGO:2000045350.030
kidney mesenchyme morphogenesisGO:007213140.030
cation transmembrane transportGO:00986552660.030
epithelial cell proliferationGO:00506731740.029
muscle fiber developmentGO:0048747760.029
digestive system developmentGO:00551232000.029
response to molecule of bacterial originGO:00022371430.029
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.029
muscle cell differentiationGO:00426922610.029
cellular protein catabolic processGO:00442571550.029
single fertilizationGO:0007338820.029
nucleoside phosphate catabolic processGO:19012922220.028
Yeast
epithelial tube morphogenesisGO:00605623030.028
intracellular protein transportGO:00068862040.028
cellular ketone metabolic processGO:0042180840.028
camera type eye developmentGO:00430102660.028
response to light stimulusGO:00094161350.028
atp metabolic processGO:0046034750.028
Yeast
neuron migrationGO:00017641220.027
negative regulation of growthGO:0045926990.027
intrinsic apoptotic signaling pathwayGO:00971931320.027
Human
negative regulation of rna splicingGO:0033119120.027
negative regulation of mitotic cell cycle phase transitionGO:1901991450.026
response to temperature stimulusGO:0009266550.026
purine ribonucleoside monophosphate catabolic processGO:0009169570.026
Yeast
dendrite developmentGO:00163581150.026
negative regulation of mitotic cell cycleGO:0045930580.026
regulation of receptor biosynthetic processGO:001086920.026
oocyte axis specificationGO:000730920.026
multi multicellular organism processGO:00447061090.026
ubiquitin dependent protein catabolic processGO:00065111290.025
organonitrogen compound catabolic processGO:19015652640.025
Yeast
single organism cell adhesionGO:00986021560.025
negative regulation of osteoblast proliferationGO:003368940.025
male sex differentiationGO:00466611090.025
regulation of cellular response to stressGO:00801351590.025
Human
purine nucleotide catabolic processGO:00061952110.024
Yeast
regulation of apoptotic signaling pathwayGO:20012331970.024
regulation of mitosisGO:0007088290.024
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.024
Human
protein modification by small protein conjugation or removalGO:00706472070.023
rhythmic processGO:00485111740.023
embryonic organ morphogenesisGO:00485622760.023
protein methylationGO:0006479810.023
body morphogenesisGO:0010171450.023
oocyte differentiationGO:0009994350.023
cytoplasmic transportGO:00164822340.022
regulation of mitotic cell cycle phase transitionGO:1901990730.022
positive regulation of translational initiationGO:004594840.022
development of primary male sexual characteristicsGO:0046546880.022
modification dependent protein catabolic processGO:00199411330.022
regulation of cellular carbohydrate metabolic processGO:0010675750.022
positive regulation of protein catabolic processGO:0045732600.022
ribonucleotide catabolic processGO:00092612080.021
Yeast
regulation of ion transmembrane transportGO:00347651190.021
negative regulation of intracellular signal transductionGO:19025321670.021
response to lipopolysaccharideGO:00324961280.021
positive regulation of cell proliferation involved in heart valve morphogenesisGO:000325110.021
membrane organizationGO:00610242450.020
rho protein signal transductionGO:0007266320.020
inorganic ion transmembrane transportGO:00986602340.020
male meiosis iGO:0007141160.020
mrna splice site selectionGO:000637650.020
heart morphogenesisGO:00030071780.020
cellular response to lipopolysaccharideGO:0071222770.020
low density lipoprotein particle receptor biosynthetic processGO:004571320.020
calcium ion transmembrane transportGO:0070588850.020
columnar cuboidal epithelial cell differentiationGO:0002065820.020
purine ribonucleoside metabolic processGO:00461282410.019
Yeast
small gtpase mediated signal transductionGO:0007264970.019
establishment or maintenance of bipolar cell polarityGO:0061245210.019
regulation of ion transportGO:00432692150.019
regulation of leukocyte differentiationGO:19021051590.019
purine nucleoside monophosphate catabolic processGO:0009128580.019
Yeast
myeloid cell differentiationGO:00300992330.019
midbrain developmentGO:0030901350.019
regulation of plasma lipoprotein particle levelsGO:0097006230.019
regulation of cell activationGO:00508652890.019
mapk cascadeGO:00001652810.019
cellular polysaccharide catabolic processGO:004424750.018
positive regulation of nervous system developmentGO:00519622210.018
transforming growth factor beta2 productionGO:003290620.018
cellularizationGO:000734910.018
striated muscle cell developmentGO:00550021250.018
male genitalia morphogenesisGO:004880840.018
leukocyte proliferationGO:00706611720.018
regulation of protein ubiquitinationGO:0031396520.017
transmembrane transportGO:00550854120.017
multicellular organismal macromolecule catabolic processGO:004426610.017
regulation of cellular catabolic processGO:00313292420.017
negative regulation of cellular component organizationGO:00511291940.017
regulation of protein catabolic processGO:00421761080.017
cell junction assemblyGO:0034329520.017
low density lipoprotein particle clearanceGO:003438380.017
positive regulation of cell cycle phase transitionGO:1901989170.017
cell cycle checkpointGO:0000075470.017
nucleoside metabolic processGO:00091162460.017
Yeast
cation transportGO:00068123990.017
cardiac muscle contractionGO:0060048320.017
embryonic appendage morphogenesisGO:00351131260.017
purine nucleotide metabolic processGO:00061633020.017
Yeast
wnt signaling pathwayGO:00160551880.016
purine nucleoside monophosphate metabolic processGO:0009126810.016
Yeast
muscle cell developmentGO:00550011330.016
lipid localizationGO:00108761260.016
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.016
multi organism behaviorGO:0051705620.016
cerebellar purkinje cell layer developmentGO:0021680260.016
nuclear transcribed mrna catabolic processGO:0000956160.016
Yeast
embryonic limb morphogenesisGO:00303261260.016
ribonucleoprotein complex disassemblyGO:003298830.016
regulation of protein localizationGO:00328802310.016
positive regulation of protein ubiquitinationGO:0031398270.016
leukocyte differentiationGO:00025213420.016
stem cell divisionGO:0017145300.016
response to nutrient levelsGO:00316671090.015
regulation of hormone levelsGO:00108172110.015
myotube differentiationGO:00149021050.015
rna catabolic processGO:0006401290.015
Yeast
microtubule based movementGO:0007018840.015
carbohydrate catabolic processGO:0016052320.015
protein ubiquitinationGO:00165671710.015
negative regulation of apoptotic signaling pathwayGO:20012341040.015
forebrain developmentGO:00309003020.015
regulation of glucose metabolic processGO:0010906600.015
muscle system processGO:00030121410.015
regulation of response to dna damage stimulusGO:2001020340.015
Human
nephrogenic mesenchyme developmentGO:007207630.015
regulation of intrinsic apoptotic signaling pathway in response to dna damageGO:1902229140.015
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.015
regulation of cell cycle phase transitionGO:1901987770.015
pole plasm assemblyGO:000731520.015
leukocyte homeostasisGO:0001776790.015
response to interleukin 4GO:0070670230.015
cellular carbohydrate metabolic processGO:00442621190.015
nucleobase containing compound transportGO:0015931270.015
proteolysis involved in cellular protein catabolic processGO:00516031470.015
glucose homeostasisGO:00425931280.015
skeletal muscle organ developmentGO:00605381630.014
positive regulation of protein modification by small protein conjugation or removalGO:1903322300.014
lung epithelium developmentGO:0060428370.014
endocytosisGO:00068971680.014
neuroepithelial cell differentiationGO:0060563370.014
regulation of cell morphogenesis involved in differentiationGO:00107691510.014
regulation of cell adhesionGO:00301551540.014
negative regulation of response to woundingGO:1903035770.014
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.014
nucleoside triphosphate catabolic processGO:00091432050.014
Yeast
spindle localizationGO:0051653220.014
limb morphogenesisGO:00351081490.014
mitotic sister chromatid segregationGO:0000070140.014
regulation of glycogen catabolic processGO:000598120.014
response to monosaccharideGO:0034284670.014
regulation of response to woundingGO:19030341890.014
multicellular organismal protein catabolic processGO:004425410.014
regulation of transmembrane transportGO:00347621280.014
carbohydrate homeostasisGO:00335001280.014
tube formationGO:00351481400.014
divalent inorganic cation transportGO:00725111780.014
lymphocyte proliferationGO:00466511640.014
ribonucleoside monophosphate metabolic processGO:0009161800.014
Yeast
dna integrity checkpointGO:0031570280.013
regulation of myeloid cell differentiationGO:0045637960.013
sensory organ morphogenesisGO:00905962420.013
negative regulation of peptidyl threonine phosphorylationGO:001080160.013
microtubule based processGO:00070172360.013
blood circulationGO:00080151950.013
low density lipoprotein receptor particle metabolic processGO:003279940.013
somite developmentGO:0061053810.013
regulation of system processGO:00440572000.013
regulation of cytokine productionGO:00018172660.013
cellular amino acid metabolic processGO:00065201030.013
macromolecular complex disassemblyGO:0032984430.013
extrinsic apoptotic signaling pathwayGO:00971911260.013
cell proliferation involved in heart valve morphogenesisGO:000324910.013
vesicle localizationGO:0051648860.013
epidermis developmentGO:00085441870.013
angiogenesisGO:00015252010.013
regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:1902253130.013
cell cycle switchingGO:006018410.013
erythrocyte differentiationGO:0030218880.013
glycogen catabolic processGO:000598050.013
positive regulation of apoptotic signaling pathwayGO:2001235950.012
positive regulation of mrna metabolic processGO:1903313170.012
inorganic cation transmembrane transportGO:00986622070.012
regulation of proteolysisGO:00301621640.012
establishment of vesicle localizationGO:0051650810.012
positive regulation of cellular protein catabolic processGO:1903364340.012
cell proliferation involved in heart valve developmentGO:200079320.012
microtubule cytoskeleton organizationGO:00002261570.012
protein targetingGO:00066051430.012
peptidyl serine phosphorylationGO:0018105740.012
endothelium developmentGO:0003158450.012
mesoderm developmentGO:00074981000.012
regulation of rna stabilityGO:0043487260.012
regulation of stem cell differentiationGO:2000736500.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
Yeast
carbohydrate biosynthetic processGO:0016051740.012
blastocyst developmentGO:0001824800.012
nucleotide catabolic processGO:00091662170.012
Yeast
regulation of neurotransmitter levelsGO:0001505870.012
lipid transportGO:0006869980.012
ear developmentGO:00435832000.012
golgi vesicle transportGO:0048193300.012
gastrulationGO:00073691160.012
positive regulation of cell cycleGO:0045787920.012
reproductive behaviorGO:0019098320.012
determination of left right symmetryGO:0007368800.012
heart processGO:0003015940.012
regulation of cytokine biosynthetic processGO:0042035590.012
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:0042771240.012
regulation of meiotic cell cycleGO:0051445340.012
nucleocytoplasmic transportGO:00069131390.011
regulation of osteoblast differentiationGO:0045667670.011
cellular component assembly involved in morphogenesisGO:00109271390.011
negative regulation of nervous system developmentGO:00519611560.011
kidney developmentGO:00018222130.011
regulation of endopeptidase activityGO:0052548890.011
single organismal cell cell adhesionGO:00163371310.011
microtubule nucleationGO:000702020.011
developmental cell growthGO:0048588840.011
cellular protein complex assemblyGO:00436231160.011
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.011
fat cell differentiationGO:00454441600.011
amide transportGO:00428861380.011
germ line stem cell maintenanceGO:003071860.011
urogenital system developmentGO:00016552610.011
nephrogenic mesenchyme morphogenesisGO:007213420.011
positive regulation of organelle organizationGO:00106381280.011
establishment of spindle localizationGO:0051293190.011
ribosomal small subunit biogenesisGO:004227440.011
smad protein complex assemblyGO:000718310.011
regulation of epidermal cell differentiationGO:0045604210.011
multicellular organismal protein metabolic processGO:004426820.011
regulation of rho protein signal transductionGO:0035023710.011
blood vessel morphogenesisGO:00485142850.011
skeletal muscle fiber developmentGO:0048741580.011
tissue homeostasisGO:00018941150.011
chemotaxisGO:00069352470.011
cell junction organizationGO:0034330770.011
regulation of neuron differentiationGO:00456642810.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
Yeast
glycosyl compound catabolic processGO:19016582060.011
Yeast
odontogenesisGO:0042476780.011
mesodermal cell migrationGO:000807840.010
actin filament organizationGO:00070151130.010
nucleobase containing small molecule metabolic processGO:00550863520.010
Yeast
peptidyl tyrosine phosphorylationGO:00181081430.010
amine metabolic processGO:0009308450.010
morphogenesis of a branching epitheliumGO:00611381930.010
regulation of striated muscle cell differentiationGO:0051153810.010
regulation of skeletal muscle cell differentiationGO:2001014110.010
aromatic compound catabolic processGO:00194392860.010
Yeast
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.010
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.010
trophectodermal cellular morphogenesisGO:000183130.010
negative regulation of synapse assemblyGO:005196430.010
multicellular organismal macromolecule metabolic processGO:0044259190.010

Ddx5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.209
muscle tissue diseaseDOID:6600.209
musculoskeletal system diseaseDOID:1700.209
muscular diseaseDOID:008000000.209
nervous system diseaseDOID:86300.126
myopathyDOID:42300.092
neurodegenerative diseaseDOID:128900.057
central nervous system diseaseDOID:33100.057
motor neuron diseaseDOID:23100.057
amyotrophic lateral sclerosisDOID:33200.017
muscular dystrophyDOID:988400.012