IMP: Integrative Multi-species Prediction

Mus musculus

13 known processes

Evx2

even skipped homeotic gene 2 homolog

(Aliases: Evx-2)

Ensembl: ENSMUSG00000001815
Entrez: 14029
UniProtKB: P49749

Process Predictions
Disease Predictions

Evx2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
placenta development	GO:0001890	140	0.824
skeletal system development	GO:0001501	356	0.813	Mouse
skeletal system morphogenesis	GO:0048705	203	0.738	Mouse
gland development	GO:0048732	330	0.717	Mouse
telencephalon development	GO:0021537	186	0.670	Mouse
positive regulation of cell development	GO:0010720	237	0.648	Mouse
regionalization	GO:0003002	337	0.631	Mouse
regulation of neuron differentiation	GO:0045664	281	0.564	Mouse
endocrine system development	GO:0035270	98	0.552	Mouse
pallium development	GO:0021543	120	0.539
embryonic organ morphogenesis	GO:0048562	276	0.524	Mouse
embryonic skeletal system development	GO:0048706	120	0.514	Mouse
axonogenesis	GO:0007409	274	0.498
neuron migration	GO:0001764	122	0.490
ectoderm formation	GO:0001705	3	0.490
hindbrain development	GO:0030902	128	0.484	Mouse
neuron fate specification	GO:0048665	30	0.480	Mouse
forebrain development	GO:0030900	302	0.471	Mouse
cerebral cortex development	GO:0021987	86	0.453
mesenchyme development	GO:0060485	152	0.451
central nervous system neuron differentiation	GO:0021953	162	0.443	Mouse
pancreatic pp cell fate commitment	GO:0003329	2	0.442
stem cell development	GO:0048864	219	0.417
forebrain generation of neurons	GO:0021872	63	0.417	Mouse
paraxial mesodermal cell fate commitment	GO:0048343	2	0.395
sensory organ morphogenesis	GO:0090596	242	0.377
camera type eye development	GO:0043010	266	0.376
forebrain neuron differentiation	GO:0021879	52	0.375	Mouse
embryonic placenta development	GO:0001892	98	0.372
stem cell differentiation	GO:0048863	268	0.362
renal tubule development	GO:0061326	87	0.358
cellular amino acid metabolic process	GO:0006520	103	0.353
regulation of cellular amino acid metabolic process	GO:0006521	5	0.353
respiratory system development	GO:0060541	190	0.352
diencephalon development	GO:0021536	63	0.346	Mouse
spinal cord oligodendrocyte cell fate specification	GO:0021530	3	0.340
embryonic skeletal system morphogenesis	GO:0048704	91	0.337	Mouse
wnt signaling pathway	GO:0016055	188	0.330
carbon catabolite repression of transcription from rna polymerase ii promoter	GO:0000437	1	0.329
axon guidance	GO:0007411	141	0.329
regulation of neural precursor cell proliferation	GO:2000177	70	0.327
lymphocyte differentiation	GO:0030098	242	0.327
outflow tract morphogenesis	GO:0003151	53	0.318
neuron projection guidance	GO:0097485	141	0.317
neural crest cell differentiation	GO:0014033	54	0.316
morphogenesis of embryonic epithelium	GO:0016331	159	0.313
muscle tissue development	GO:0060537	308	0.307
bmp signaling pathway	GO:0030509	93	0.303
nephron tubule development	GO:0072080	84	0.300
pancreatic a cell fate commitment	GO:0003326	2	0.298
ear morphogenesis	GO:0042471	118	0.291
cellular ketone metabolic process	GO:0042180	84	0.291
mesenchymal cell development	GO:0014031	93	0.289
neural precursor cell proliferation	GO:0061351	121	0.287
ossification	GO:0001503	216	0.284
cation transport	GO:0006812	399	0.280
spleen development	GO:0048536	39	0.280
connective tissue development	GO:0061448	179	0.279	Mouse
leukocyte differentiation	GO:0002521	342	0.277
striated muscle tissue development	GO:0014706	293	0.276
developmental maturation	GO:0021700	193	0.269
ear development	GO:0043583	200	0.261
canonical wnt signaling pathway	GO:0060070	130	0.260
segmentation	GO:0035282	93	0.258
metencephalon development	GO:0022037	89	0.252
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.252
cartilage development	GO:0051216	140	0.251	Mouse
positive regulation of neuron differentiation	GO:0045666	141	0.249	Mouse
forebrain cell migration	GO:0021885	58	0.244
epidermis development	GO:0008544	187	0.242
glomerular mesangial cell differentiation	GO:0072008	3	0.233
digestive tract development	GO:0048565	190	0.231
tube formation	GO:0035148	140	0.230
cerebral cortex cell migration	GO:0021795	44	0.226
mesonephric epithelium development	GO:0072163	94	0.225
epithelial tube formation	GO:0072175	130	0.225
paraxial mesodermal cell differentiation	GO:0048342	2	0.222
retina development in camera type eye	GO:0060041	119	0.221
glandular epithelial cell differentiation	GO:0002067	38	0.219
cell fate specification	GO:0001708	72	0.215	Mouse
carbon catabolite activation of transcription from rna polymerase ii promoter	GO:0000436	4	0.211
limbic system development	GO:0021761	72	0.209	Mouse
molting cycle	GO:0042303	90	0.208
neuroblast proliferation	GO:0007405	49	0.208
ureteric bud morphogenesis	GO:0060675	62	0.204
neural tube development	GO:0021915	160	0.204
bone development	GO:0060348	120	0.202
regulation of organ morphogenesis	GO:2000027	144	0.199
locomotory behavior	GO:0007626	195	0.196
hair cycle	GO:0042633	90	0.195
telencephalon cell migration	GO:0022029	55	0.195
cell fate commitment	GO:0045165	210	0.195	Mouse
t cell activation	GO:0042110	289	0.195
regulation of cell cycle	GO:0051726	281	0.195
regulation of wnt signaling pathway	GO:0030111	123	0.195
regulation of transmembrane transport	GO:0034762	128	0.193
mesoderm development	GO:0007498	100	0.193
cardiac chamber morphogenesis	GO:0003206	93	0.192
cellular amine metabolic process	GO:0044106	44	0.190
amine metabolic process	GO:0009308	45	0.188
nephron tubule morphogenesis	GO:0072078	68	0.186
lung epithelium development	GO:0060428	37	0.185
dendrite development	GO:0016358	115	0.182
positive regulation of nervous system development	GO:0051962	221	0.178	Mouse
hippocampus development	GO:0021766	52	0.177
formation of primary germ layer	GO:0001704	77	0.173
cytokine production	GO:0001816	319	0.170
somitogenesis	GO:0001756	69	0.170
ventral spinal cord interneuron fate commitment	GO:0060579	14	0.169	Mouse
myeloid cell differentiation	GO:0030099	233	0.168
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	GO:0060528	4	0.167
mesonephric tubule morphogenesis	GO:0072171	63	0.166
prostate gland stromal morphogenesis	GO:0060741	2	0.164
cell fate determination involved in pattern specification	GO:0060582	1	0.163
wound healing	GO:0042060	157	0.163
cell differentiation in spinal cord	GO:0021515	53	0.162	Mouse
regulation of cellular amine metabolic process	GO:0033238	20	0.160
stem cell proliferation	GO:0072089	117	0.159
nephron morphogenesis	GO:0072028	69	0.156
pancreatic pp cell differentiation	GO:0003312	2	0.154
skin development	GO:0043588	220	0.152
skeletal muscle cell differentiation	GO:0035914	66	0.152
regulation of stem cell proliferation	GO:0072091	78	0.150
mesenchymal cell differentiation	GO:0048762	107	0.149
pyramidal neuron migration	GO:0021852	1	0.148
multicellular organism growth	GO:0035264	161	0.147
cerebral cortex radially oriented cell migration	GO:0021799	31	0.147
peptidyl amino acid modification	GO:0018193	336	0.146
cation transmembrane transport	GO:0098655	266	0.146
mesoderm morphogenesis	GO:0048332	64	0.144
calcium ion transport	GO:0006816	159	0.144
hair follicle development	GO:0001942	85	0.144
cell maturation	GO:0048469	127	0.143
notch signaling pathway	GO:0007219	71	0.142	Mouse
organic hydroxy compound metabolic process	GO:1901615	203	0.141
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.141
kidney morphogenesis	GO:0060993	83	0.141
neural crest cell development	GO:0014032	48	0.140
lung development	GO:0030324	164	0.140
embryonic epithelial tube formation	GO:0001838	130	0.140
cell fate determination	GO:0001709	32	0.140
ventricular cardiac muscle tissue morphogenesis	GO:0055010	32	0.139
mitotic cell cycle	GO:0000278	195	0.138
regulation of ion transport	GO:0043269	215	0.137
spinal cord oligodendrocyte cell differentiation	GO:0021529	3	0.137
epithelial cell fate commitment	GO:0072148	13	0.137
negative regulation of cell development	GO:0010721	169	0.135
smoothened signaling pathway	GO:0007224	105	0.133
multi multicellular organism process	GO:0044706	109	0.133
regulation of auditory receptor cell differentiation	GO:0045607	4	0.132
positive regulation of transcription via serum response element binding	GO:0010735	1	0.132
glial cell differentiation	GO:0010001	131	0.131	Mouse
neuron fate determination	GO:0048664	9	0.130
nephron development	GO:0072006	109	0.129
stem cell maintenance	GO:0019827	130	0.129
auditory receptor cell fate determination	GO:0042668	3	0.126
spinal cord dorsal ventral patterning	GO:0021513	23	0.126	Mouse
epithelial tube morphogenesis	GO:0060562	303	0.125
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.124
morphogenesis of a branching structure	GO:0001763	203	0.123
mesoderm formation	GO:0001707	62	0.122
rhythmic process	GO:0048511	174	0.121
t cell differentiation	GO:0030217	174	0.121
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process	GO:2000763	1	0.120
homeostasis of number of cells	GO:0048872	210	0.119
urogenital system development	GO:0001655	261	0.116
ventral spinal cord interneuron differentiation	GO:0021514	16	0.116	Mouse
chondrocyte differentiation	GO:0002062	72	0.115
cell type specific apoptotic process	GO:0097285	268	0.114
kidney epithelium development	GO:0072073	121	0.112
negative regulation of cell proliferation	GO:0008285	296	0.112
regulation of mitotic cell cycle	GO:0007346	126	0.112
epithelial cell differentiation involved in prostate gland development	GO:0060742	13	0.112
calcium ion transmembrane transport	GO:0070588	85	0.111
branching morphogenesis of an epithelial tube	GO:0048754	159	0.111
pituitary gland development	GO:0021983	38	0.110	Mouse
nephron epithelium development	GO:0072009	92	0.110
regulation of secretion by cell	GO:1903530	249	0.110
chemotaxis	GO:0006935	247	0.109
positive regulation of neuroblast proliferation	GO:0002052	19	0.109
limb development	GO:0060173	166	0.109
spinal cord patterning	GO:0021511	25	0.109	Mouse
regulation of neuron projection development	GO:0010975	169	0.108
blood vessel morphogenesis	GO:0048514	285	0.108
autonomic nervous system development	GO:0048483	43	0.108
carbon catabolite regulation of transcription	GO:0045990	4	0.108
pattern specification involved in metanephros development	GO:0072268	4	0.106
lung cell differentiation	GO:0060479	30	0.105
apoptotic signaling pathway	GO:0097190	306	0.105
cerebellum development	GO:0021549	77	0.105
catecholamine metabolic process	GO:0006584	30	0.105
myeloid cell homeostasis	GO:0002262	114	0.105
cardiac muscle tissue development	GO:0048738	130	0.103
germ cell development	GO:0007281	185	0.102
oligodendrocyte differentiation	GO:0048709	53	0.102	Mouse
regulation of blood circulation	GO:1903522	93	0.101
regulation of cellular ketone metabolic process	GO:0010565	66	0.101
positive regulation of stem cell proliferation	GO:2000648	59	0.100
inner ear morphogenesis	GO:0042472	101	0.100
ventral spinal cord development	GO:0021517	48	0.100	Mouse
mesonephros development	GO:0001823	97	0.100
somite development	GO:0061053	81	0.099
glial cell fate commitment	GO:0021781	14	0.099
regulation of metal ion transport	GO:0010959	106	0.098
negative regulation of ossification	GO:0030279	49	0.098
erythrocyte differentiation	GO:0030218	88	0.098
cardiocyte differentiation	GO:0035051	87	0.098
divalent inorganic cation transport	GO:0072511	178	0.097
auditory receptor cell fate specification	GO:0042667	1	0.096
regulation of neuroblast proliferation	GO:1902692	27	0.096
heart morphogenesis	GO:0003007	178	0.096
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.096
brain morphogenesis	GO:0048854	32	0.095	Mouse
metanephric capsule morphogenesis	GO:0072265	1	0.093
mesangial cell differentiation	GO:0072007	4	0.093
developmental induction	GO:0031128	34	0.092
organonitrogen compound biosynthetic process	GO:1901566	192	0.092
renal capsule morphogenesis	GO:0072128	1	0.091
cardiac pacemaker cell fate commitment	GO:0060927	1	0.091
regulation of cell migration involved in sprouting angiogenesis	GO:0090049	4	0.091
response to growth factor	GO:0070848	198	0.091
b cell activation	GO:0042113	161	0.089
positive regulation of transcription by glucose	GO:0046016	3	0.089
somatotropin secreting cell differentiation	GO:0060126	4	0.088
transmission of nerve impulse	GO:0019226	76	0.088
purine nucleotide biosynthetic process	GO:0006164	65	0.088
digestive system development	GO:0055123	200	0.088
feeding behavior	GO:0007631	62	0.088
negative regulation of cellular amine metabolic process	GO:0033239	1	0.088
peptidyl tyrosine phosphorylation	GO:0018108	143	0.088
hypophysis morphogenesis	GO:0048850	3	0.087
appendage development	GO:0048736	166	0.087
hair follicle morphogenesis	GO:0031069	29	0.087
muscle tissue morphogenesis	GO:0060415	53	0.087
neuromuscular process	GO:0050905	99	0.086
spinal cord development	GO:0021510	81	0.086	Mouse
response to radiation	GO:0009314	165	0.085
renal tubule morphogenesis	GO:0061333	72	0.084
regulation of cardioblast differentiation	GO:0051890	3	0.084
female somatic sex determination	GO:0019101	1	0.084
developmental growth involved in morphogenesis	GO:0060560	138	0.083
cellular response to growth factor stimulus	GO:0071363	197	0.083
cardiac septum development	GO:0003279	59	0.080
positive regulation of cell death	GO:0010942	224	0.080
regulation of glial cell differentiation	GO:0045685	41	0.080	Mouse
regulation of bmp signaling pathway	GO:0030510	60	0.080
carbon catabolite regulation of transcription from rna polymerase ii promoter	GO:0000429	4	0.080
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.079
mesonephric tubule development	GO:0072164	94	0.078
metanephric capsule specification	GO:0072267	1	0.078
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	40	0.078
atrioventricular node cell differentiation	GO:0060922	2	0.078
inorganic cation transmembrane transport	GO:0098662	207	0.077
embryonic heart tube morphogenesis	GO:0003143	51	0.077
epithelial cell maturation involved in prostate gland development	GO:0060743	4	0.076
positive regulation of apoptotic process	GO:0043065	217	0.076
epithelial to mesenchymal transition	GO:0001837	47	0.076
cardiac chamber development	GO:0003205	108	0.076
positive regulation of transcription from rna polymerase ii promoter by glucose	GO:0000432	3	0.075
metanephric capsule formation	GO:0072266	1	0.075
positive regulation of cellular amine metabolic process	GO:0033240	5	0.075
cerebral cortex neuron differentiation	GO:0021895	19	0.075
renal capsule formation	GO:0072129	1	0.075
cardiac neural crest cell development involved in heart development	GO:0061308	7	0.074
positive regulation of epithelial cell proliferation	GO:0050679	68	0.074
b cell differentiation	GO:0030183	78	0.074
mesangial cell development	GO:0072143	4	0.074
negative regulation of growth	GO:0045926	99	0.074
nephron epithelium morphogenesis	GO:0072088	68	0.072
respiratory tube development	GO:0030323	167	0.072
oligodendrocyte development	GO:0014003	20	0.072
carbohydrate metabolic process	GO:0005975	230	0.072
g protein coupled receptor signaling pathway	GO:0007186	243	0.072
cell proliferation in forebrain	GO:0021846	30	0.071
cardiac neural crest cell migration involved in outflow tract morphogenesis	GO:0003253	3	0.071
cellular homeostasis	GO:0019725	240	0.071
endoderm development	GO:0007492	45	0.070
alpha beta t cell activation	GO:0046631	91	0.070
neural tube closure	GO:0001843	90	0.070
cell differentiation involved in kidney development	GO:0061005	33	0.070
cell fate commitment involved in pattern specification	GO:0060581	14	0.069	Mouse
brain segmentation	GO:0035284	3	0.069
spinal cord motor neuron differentiation	GO:0021522	35	0.068
multicellular organismal signaling	GO:0035637	91	0.068
positive regulation of cell cycle	GO:0045787	92	0.068
epithelial cell proliferation	GO:0050673	174	0.068
adult behavior	GO:0030534	135	0.067
middle ear morphogenesis	GO:0042474	23	0.067
negative regulation of neuron death	GO:1901215	98	0.067
glomerular mesangial cell development	GO:0072144	3	0.066
apoptotic process involved in outflow tract morphogenesis	GO:0003275	2	0.066
forebrain neuron development	GO:0021884	30	0.066
protein ubiquitination	GO:0016567	171	0.065
regulation of canonical wnt signaling pathway	GO:0060828	82	0.065
ureteric bud development	GO:0001657	94	0.065
atrioventricular node cell development	GO:0060928	2	0.065
lung epithelial cell differentiation	GO:0060487	29	0.064
cell differentiation in hindbrain	GO:0021533	24	0.064
divalent metal ion transport	GO:0070838	172	0.064
chromatin organization	GO:0006325	206	0.063
regulation of osteoblast differentiation	GO:0045667	67	0.063
pharynx development	GO:0060465	1	0.063
branching involved in ureteric bud morphogenesis	GO:0001658	56	0.063
embryonic viscerocranium morphogenesis	GO:0048703	8	0.062
circulatory system process	GO:0003013	197	0.062
carbon catabolite activation of transcription	GO:0045991	4	0.062
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	GO:2000802	1	0.062
negative regulation of glucokinase activity	GO:0033132	4	0.061
neural crest cell migration	GO:0001755	32	0.061
cell cell signaling involved in cell fate commitment	GO:0045168	35	0.061
embryonic digit morphogenesis	GO:0042733	56	0.061
embryonic appendage morphogenesis	GO:0035113	126	0.060
neural tube patterning	GO:0021532	43	0.060
cellular carbohydrate metabolic process	GO:0044262	119	0.060
cell growth	GO:0016049	130	0.059
neuron death	GO:0070997	154	0.059
regulation of cell cycle process	GO:0010564	160	0.059
pancreas development	GO:0031016	57	0.058
angiogenesis	GO:0001525	201	0.058
developmental programmed cell death	GO:0010623	41	0.058
cerebral cortex gabaergic interneuron differentiation	GO:0021892	9	0.058
negative regulation of nervous system development	GO:0051961	156	0.058
cytoplasmic transport	GO:0016482	234	0.058
blastocyst formation	GO:0001825	33	0.058
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	GO:2000800	1	0.058
regulation of cytokine production	GO:0001817	266	0.057
hormone secretion	GO:0046879	128	0.057
apoptotic process involved in morphogenesis	GO:0060561	25	0.057
neural nucleus development	GO:0048857	22	0.057
positive regulation of keratinocyte proliferation	GO:0010838	4	0.057
phenol containing compound metabolic process	GO:0018958	60	0.057
regulation of histone modification	GO:0031056	56	0.057
membrane organization	GO:0061024	245	0.057
astrocyte differentiation	GO:0048708	43	0.057
negative regulation of apoptotic process involved in outflow tract morphogenesis	GO:1902257	2	0.056
mesenchyme morphogenesis	GO:0072132	32	0.056
positive regulation of transcription from rna polymerase iii promoter	GO:0045945	1	0.056
neurohypophysis development	GO:0021985	2	0.056
cell fate commitment involved in formation of primary germ layer	GO:0060795	26	0.056
gliogenesis	GO:0042063	141	0.055	Mouse
positive regulation of growth	GO:0045927	104	0.055
neural tube formation	GO:0001841	108	0.055
pulmonary myocardium development	GO:0003350	3	0.055
cell proliferation involved in outflow tract morphogenesis	GO:0061325	4	0.055
auditory receptor cell differentiation	GO:0042491	37	0.055
positive regulation of inner ear receptor cell differentiation	GO:2000982	1	0.054
cell division	GO:0051301	120	0.054
endodermal cell fate specification	GO:0001714	4	0.054
gastrulation	GO:0007369	116	0.054
nuclear transport	GO:0051169	139	0.054
chromatin modification	GO:0016568	187	0.054
primary neural tube formation	GO:0014020	95	0.054
epithelial mesenchymal signaling involved in prostate gland development	GO:0060738	2	0.054
regulation of epidermis development	GO:0045682	33	0.054
endoderm formation	GO:0001706	20	0.054
neural retina development	GO:0003407	41	0.054
gabaergic neuron differentiation	GO:0097154	11	0.054
kidney development	GO:0001822	213	0.053
hair cell differentiation	GO:0035315	40	0.053
regulation of retina development in camera type eye	GO:1902866	3	0.053
positive regulation of homeostatic process	GO:0032846	64	0.053
positive regulation of vascular wound healing	GO:0035470	1	0.053
cardiac epithelial to mesenchymal transition	GO:0060317	18	0.052
detection of stimulus	GO:0051606	84	0.052
negative regulation of hexokinase activity	GO:1903300	4	0.052
regulation of secretion	GO:0051046	274	0.052
regulation of nuclear division	GO:0051783	56	0.051
regulation of carbohydrate metabolic process	GO:0006109	75	0.051
negative regulation of intracellular signal transduction	GO:1902532	167	0.051
renal system development	GO:0072001	225	0.050
negative regulation of cell cycle	GO:0045786	123	0.050
cardiac ventricle morphogenesis	GO:0003208	50	0.050
dna metabolic process	GO:0006259	303	0.050
mitotic cell cycle process	GO:1903047	159	0.049
bone morphogenesis	GO:0060349	78	0.049
regulation of myeloid cell differentiation	GO:0045637	96	0.049
regulation of neural retina development	GO:0061074	3	0.049
negative regulation of wnt signaling pathway	GO:0030178	73	0.049
purkinje myocyte differentiation	GO:0003168	1	0.049
cation homeostasis	GO:0055080	212	0.049
mitral valve development	GO:0003174	4	0.049
cranial nerve development	GO:0021545	41	0.049	Mouse
regulation of apoptotic signaling pathway	GO:2001233	197	0.049
regulation of cell projection organization	GO:0031344	206	0.048
vascular wound healing	GO:0061042	3	0.048
prostate gland epithelium morphogenesis	GO:0060740	31	0.048
mammary gland morphogenesis	GO:0060443	54	0.048
regulation of epidermal cell differentiation	GO:0045604	21	0.048
fat cell differentiation	GO:0045444	160	0.048
response to organonitrogen compound	GO:0010243	246	0.048
blood circulation	GO:0008015	195	0.048
purine containing compound metabolic process	GO:0072521	311	0.048
muscle cell development	GO:0055001	133	0.047
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.047
cellular response to external stimulus	GO:0071496	88	0.047
positive regulation of cell adhesion	GO:0045785	80	0.047
skin morphogenesis	GO:0043589	38	0.047
leukocyte apoptotic process	GO:0071887	71	0.047
neuron apoptotic process	GO:0051402	142	0.047
head morphogenesis	GO:0060323	34	0.047
myeloid leukocyte differentiation	GO:0002573	119	0.047
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.047
positive regulation of cell migration involved in sprouting angiogenesis	GO:0090050	3	0.047
positive regulation of secretion by cell	GO:1903532	114	0.047
positive regulation of meiotic cell cycle	GO:0051446	15	0.046
inner ear receptor cell differentiation	GO:0060113	61	0.046
negative regulation of molecular function	GO:0044092	258	0.046
morphogenesis of a branching epithelium	GO:0061138	193	0.046
positive regulation of neural precursor cell proliferation	GO:2000179	42	0.046
positive regulation of cell motility	GO:2000147	116	0.046
positive regulation of lymphocyte activation	GO:0051251	140	0.046
detection of glucose	GO:0051594	1	0.045
ovulation cycle	GO:0042698	59	0.045
protein modification by small protein conjugation or removal	GO:0070647	207	0.045
transmembrane transport	GO:0055085	412	0.045
intracellular protein transport	GO:0006886	204	0.045
astrocyte fate commitment	GO:0060018	4	0.045
cell proliferation in hindbrain	GO:0021534	10	0.045
tube closure	GO:0060606	91	0.045
cerebral cortex radial glia guided migration	GO:0021801	17	0.045
cellular response to dna damage stimulus	GO:0006974	207	0.045
dorsal ventral neural tube patterning	GO:0021904	28	0.044
oligodendrocyte cell fate commitment	GO:0021779	5	0.044
regulation of organ formation	GO:0003156	34	0.044
digestive tract morphogenesis	GO:0048546	147	0.044
negative regulation of transcription from rna polymerase ii promoter by glucose	GO:0000433	1	0.044
somite rostral caudal axis specification	GO:0032525	13	0.044
extracellular matrix organization	GO:0030198	147	0.044
hypothalamus cell differentiation	GO:0021979	8	0.043
visceral serous pericardium development	GO:0061032	2	0.043
inorganic ion transmembrane transport	GO:0098660	234	0.043
embryonic limb morphogenesis	GO:0030326	126	0.043
cardiac septum morphogenesis	GO:0060411	46	0.043
response to light stimulus	GO:0009416	135	0.043
lateral inhibition	GO:0046331	1	0.043
endocardial cushion to mesenchymal transition involved in heart valve formation	GO:0003199	4	0.043
sensory perception of sound	GO:0007605	97	0.043
regulation of cell growth	GO:0001558	91	0.043
globus pallidus development	GO:0021759	2	0.043
cardioblast proliferation	GO:0003263	8	0.042
regulation of cellular component size	GO:0032535	121	0.042
negative regulation of neuron differentiation	GO:0045665	101	0.042
regulation of cell migration	GO:0030334	219	0.042	Mouse
columnar cuboidal epithelial cell development	GO:0002066	29	0.042
metal ion homeostasis	GO:0055065	189	0.042
regulation of transcription from rna polymerase iii promoter	GO:0006359	2	0.042
striated muscle cell proliferation	GO:0014855	39	0.041
tumor necrosis factor production	GO:0032640	50	0.041
detection of monosaccharide stimulus	GO:0034287	1	0.041
adult locomotory behavior	GO:0008344	91	0.041
retina morphogenesis in camera type eye	GO:0060042	45	0.041
epidermis morphogenesis	GO:0048730	33	0.041
ribose phosphate metabolic process	GO:0019693	291	0.040
somatic sex determination	GO:0018993	2	0.040
regulation of membrane potential	GO:0042391	192	0.040
regulation of neuron apoptotic process	GO:0043523	122	0.040
ribose phosphate biosynthetic process	GO:0046390	59	0.040
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.040
metanephric capsule development	GO:0072213	1	0.040
central nervous system neuron development	GO:0021954	67	0.040
sensory system development	GO:0048880	3	0.040
regulation of hormone levels	GO:0010817	211	0.040
ventral spinal cord interneuron fate determination	GO:0060580	1	0.039
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.039
heart formation	GO:0060914	16	0.039
sensory perception	GO:0007600	245	0.039
regulation of epithelial cell proliferation	GO:0050678	141	0.039
cardiac ventricle development	GO:0003231	83	0.038
midbrain development	GO:0030901	35	0.038
nephric duct elongation	GO:0035849	1	0.038
organophosphate biosynthetic process	GO:0090407	122	0.038
paraxial mesoderm development	GO:0048339	18	0.038
regulation of organ growth	GO:0046620	61	0.038
modification dependent macromolecule catabolic process	GO:0043632	133	0.038
mesodermal cell differentiation	GO:0048333	22	0.038
regulation of calcium ion transport	GO:0051924	69	0.038
cellular response to hormone stimulus	GO:0032870	150	0.037
cardiac right ventricle formation	GO:0003219	3	0.037
prostate glandular acinus development	GO:0060525	12	0.037
positive regulation of organelle organization	GO:0010638	128	0.037
positive regulation of auditory receptor cell differentiation	GO:0045609	1	0.037
nucleotide metabolic process	GO:0009117	332	0.037
neuroblast differentiation	GO:0014016	2	0.037
regulation of cell motility	GO:2000145	236	0.036	Mouse
cellular response to extracellular stimulus	GO:0031668	81	0.036
regulation of embryonic development	GO:0045995	71	0.036
regulation of voltage gated calcium channel activity	GO:1901385	4	0.036
endocytosis	GO:0006897	168	0.036
ribonucleotide biosynthetic process	GO:0009260	59	0.036
odontogenesis	GO:0042476	78	0.036
regulation of cell activation	GO:0050865	289	0.036
lung morphogenesis	GO:0060425	50	0.036
signal transduction in absence of ligand	GO:0038034	55	0.036
negative regulation of canonical wnt signaling pathway	GO:0090090	51	0.036
negative regulation of neuron apoptotic process	GO:0043524	92	0.036
transcription from rna polymerase iii promoter	GO:0006383	3	0.035

Evx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.073
gastrointestinal system disease	DOID:77	0.073
nervous system disease	DOID:863	0.039

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