Mus musculus

0 known processes

Eme1

essential meiotic endonuclease 1 homolog 1 (S. pombe)

(Aliases: 6820428D13,MGC106543)

Eme1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.601
dna repairGO:00062811070.316
meiotic nuclear divisionGO:00071261150.239
nuclear divisionGO:00002801580.130
organic cyclic compound catabolic processGO:19013612950.127
cellular response to dna damage stimulusGO:00069742070.113
microtubule cytoskeleton organization involved in mitosisGO:190285040.108
organelle fissionGO:00482851700.090
organonitrogen compound catabolic processGO:19015652640.088
cellular nitrogen compound catabolic processGO:00442702800.087
metaphase plate congressionGO:005131020.086
meiotic cell cycleGO:00513211220.085
purine ribonucleoside triphosphate metabolic processGO:00092052200.081
mitotic sister chromatid cohesionGO:000706410.079
cellular amino acid metabolic processGO:00065201030.075
heterocycle catabolic processGO:00467002800.071
regulation of cell cycleGO:00517262810.068
macromolecule catabolic processGO:00090572810.068
male meiosisGO:0007140370.068
nucleoside metabolic processGO:00091162460.066
regulation of organelle organizationGO:00330432890.060
spindle assembly involved in mitosisGO:009030740.056
mitotic cell cycle processGO:19030471590.055
microtubule based processGO:00070172360.054
cell divisionGO:00513011200.052
nucleoside catabolic processGO:00091642060.051
gland developmentGO:00487323300.050
meiotic cell cycle processGO:1903046770.050
purine nucleotide catabolic processGO:00061952110.049
atp catabolic processGO:0006200550.049
protein catabolic processGO:00301632210.049
regulation of cell cycle processGO:00105641600.049
nucleobase containing small molecule metabolic processGO:00550863520.048
ribonucleoside metabolic processGO:00091192450.045
purine nucleoside catabolic processGO:00061522050.044
histone modificationGO:00165701590.042
purine ribonucleoside metabolic processGO:00461282410.041
nucleoside triphosphate catabolic processGO:00091432050.040
regulation of mitotic cell cycle phase transitionGO:1901990730.039
organelle assemblyGO:00709251770.039
negative regulation of cell cycle phase transitionGO:1901988480.037
centrosome separationGO:005129940.037
negative regulation of cellular component organizationGO:00511291940.037
nucleoside phosphate metabolic processGO:00067533380.037
purine nucleoside metabolic processGO:00422782410.036
mitotic chromosome condensationGO:000707610.035
chromosome segregationGO:0007059480.035
centrosome organizationGO:0051297260.033
nucleoside triphosphate metabolic processGO:00091412300.033
spermatogenesisGO:00072832840.033
modification dependent macromolecule catabolic processGO:00436321330.033
response to cell cycle checkpoint signalingGO:007239610.033
Human
mitotic cell cycleGO:00002781950.032
positive regulation of chromosome segregationGO:005198440.032
nucleoside phosphate catabolic processGO:19012922220.032
regulation of cellular amine metabolic processGO:0033238200.031
nucleic acid phosphodiester bond hydrolysisGO:0090305490.031
glycosyl compound metabolic processGO:19016572460.031
glycosyl compound catabolic processGO:19016582060.031
cleavage furrow formationGO:003608920.031
protein modification by small protein conjugationGO:00324461870.029
chromatin silencingGO:0006342150.029
regulation of cellular amino acid metabolic processGO:000652150.029
regulation of proteolysisGO:00301621640.029
somatic recombination of immunoglobulin gene segmentsGO:0016447420.028
regulation of cellular ketone metabolic processGO:0010565660.028
immune effector processGO:00022523210.028
divalent metal ion transportGO:00708381720.027
nucleoside monophosphate catabolic processGO:0009125590.026
microtubule cytoskeleton organizationGO:00002261570.026
aromatic compound catabolic processGO:00194392860.026
purine ribonucleoside catabolic processGO:00461302050.026
double strand break repairGO:0006302480.026
female meiosis chromosome segregationGO:001632110.026
digestive tract developmentGO:00485651900.025
purine containing compound metabolic processGO:00725213110.025
ribonucleoside triphosphate catabolic processGO:00092031990.025
maintenance of locationGO:0051235890.024
ribonucleoside catabolic processGO:00424542060.024
dna catabolic process exonucleolyticGO:000073830.024
cellular ketone metabolic processGO:0042180840.024
endomembrane system organizationGO:00102561470.023
response to acid chemicalGO:00011011110.023
sister chromatid cohesionGO:0007062120.023
covalent chromatin modificationGO:00165691630.023
positive regulation of cellular catabolic processGO:00313311480.023
response to radiationGO:00093141650.023
protein complex disassemblyGO:0043241400.023
hepaticobiliary system developmentGO:0061008670.023
cellularizationGO:000734910.023
purine ribonucleoside triphosphate catabolic processGO:00092071990.023
modification dependent protein catabolic processGO:00199411330.022
nucleotide catabolic processGO:00091662170.022
proteolysis involved in cellular protein catabolic processGO:00516031470.022
regulation of hydrolase activityGO:00513362460.022
germ cell developmentGO:00072811850.022
chromatin modificationGO:00165681870.021
cellular protein catabolic processGO:00442571550.021
purine nucleotide metabolic processGO:00061633020.021
protein processingGO:00164851630.021
gene silencingGO:0016458380.021
regulation of protein catabolic processGO:00421761080.021
leukocyte migrationGO:00509001240.020
purine nucleoside triphosphate metabolic processGO:00091442260.020
cation transportGO:00068123990.020
blood vessel morphogenesisGO:00485142850.020
immunoglobulin mediated immune responseGO:0016064690.020
production of molecular mediator of immune responseGO:00024401030.020
negative regulation of molecular functionGO:00440922580.020
ribonucleotide catabolic processGO:00092612080.020
negative regulation of organelle organizationGO:0010639900.020
protein maturationGO:00516041760.020
regulation of mitotic cell cycleGO:00073461260.020
adaptive immune responseGO:00022501550.020
positive regulation of cellular amino acid metabolic processGO:004576430.019
protein localization to organelleGO:00333651850.019
organelle localizationGO:00516401790.019
purine ribonucleotide catabolic processGO:00091542080.019
purine nucleoside triphosphate catabolic processGO:00091462030.019
lymphocyte activation involved in immune responseGO:0002285930.019
regulation of microtubule cytoskeleton organizationGO:0070507370.019
positive regulation of cellular amine metabolic processGO:003324050.019
regulation of mapk cascadeGO:00434082480.019
regulation of cell divisionGO:0051302760.019
striated muscle tissue developmentGO:00147062930.019
cellular protein complex assemblyGO:00436231160.018
protein localization to chromosome centromeric regionGO:007145910.018
endocytosisGO:00068971680.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
negative regulation of cell proliferationGO:00082852960.018
response to organonitrogen compoundGO:00102432460.018
posttranscriptional regulation of gene expressionGO:00106081550.018
organophosphate catabolic processGO:00464342320.018
negative regulation of protein processingGO:0010955790.018
dna biosynthetic processGO:0071897220.018
cell adhesionGO:00071553290.017
establishment of meiotic spindle orientationGO:005129610.017
guanosine containing compound catabolic processGO:19010691440.017
regulation of cellular component sizeGO:00325351210.017
cellular amine metabolic processGO:0044106440.017
negative regulation of cytoskeleton organizationGO:0051494360.017
meiotic dna repair synthesisGO:000071140.017
oxidation reduction processGO:00551143420.017
dna endoreduplicationGO:004202340.017
establishment of organelle localizationGO:00516561220.017
carbohydrate derivative catabolic processGO:19011362310.016
positive regulation of mitotic metaphase anaphase transitionGO:004584220.016
negative regulation of microtubule polymerization or depolymerizationGO:0031111150.016
divalent inorganic cation transportGO:00725111780.016
wnt signaling pathwayGO:00160551880.016
b cell activationGO:00421131610.016
nucleotide metabolic processGO:00091173320.016
dna catabolic process endonucleolyticGO:0000737150.016
microtubule polymerization or depolymerizationGO:0031109260.016
leukocyte mediated immunityGO:00024431740.016
regulation of cytokine productionGO:00018172660.016
forebrain developmentGO:00309003020.016
ribose phosphate metabolic processGO:00196932910.016
reactive oxygen species metabolic processGO:0072593840.016
dna dependent dna replication maintenance of fidelityGO:004500530.015
negative regulation of cell developmentGO:00107211690.015
cellular response to biotic stimulusGO:0071216920.015
Human
cytokine productionGO:00018163190.015
regulation of chromatin silencingGO:003193520.015
b cell activation involved in immune responseGO:0002312500.015
microtubule nucleationGO:000702020.015
generation of precursor metabolites and energyGO:00060911030.015
cellular response to cytokine stimulusGO:00713451890.015
cellular homeostasisGO:00197252400.015
placenta developmentGO:00018901400.015
negative regulation of protein metabolic processGO:00512482820.014
somatic diversification of immune receptors via somatic mutationGO:000256680.014
amine metabolic processGO:0009308450.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.014
peptide hormone secretionGO:00300721090.014
regulation of protein localizationGO:00328802310.014
protein polymerizationGO:0051258570.014
b cell mediated immunityGO:0019724710.014
cell cycle g1 s phase transitionGO:0044843570.014
spindle assembly involved in female meiosisGO:000705630.014
anatomical structure homeostasisGO:00602491450.014
mapk cascadeGO:00001652810.014
mitotic nuclear divisionGO:0007067480.013
regulation of anatomical structure sizeGO:00900661780.013
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.013
spindle localizationGO:0051653220.013
regulation of cellular catabolic processGO:00313292420.013
membrane organizationGO:00610242450.013
protein depolymerizationGO:0051261340.013
regulation of mitotic spindle organizationGO:006023620.013
positive regulation of cellular protein catabolic processGO:1903364340.013
chromatin organizationGO:00063252060.013
negative regulation of phosphorus metabolic processGO:00105631840.013
regulation of mitotic sister chromatid segregationGO:0033047120.013
nuclear transportGO:00511691390.013
positive regulation of histone methylationGO:0031062160.013
dna recombinationGO:0006310920.013
ras protein signal transductionGO:0007265770.013
regulation of cell cycle g2 m phase transitionGO:1902749100.013
positive regulation of nucleoside metabolic processGO:0045979910.013
establishment or maintenance of cell polarityGO:0007163860.013
protein ubiquitinationGO:00165671710.013
regionalizationGO:00030023370.013
negative regulation of cell cycleGO:00457861230.012
mitotic centrosome separationGO:000710040.012
lymphocyte mediated immunityGO:00024491390.012
leukocyte activation involved in immune responseGO:00023661260.012
regulation of cellular response to stressGO:00801351590.012
ossificationGO:00015032160.012
establishment or maintenance of cytoskeleton polarityGO:003095220.012
negative regulation of cellular protein metabolic processGO:00322692470.012
rhythmic processGO:00485111740.012
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.012
regulation of neuron differentiationGO:00456642810.012
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.012
response to mineralocorticoidGO:005138510.012
cellular response to organonitrogen compoundGO:00714171450.012
ribonucleotide metabolic processGO:00092592910.012
histone monoubiquitinationGO:001039030.012
humoral immune responseGO:0006959570.012
somatic diversification of immune receptorsGO:0002200530.012
positive regulation of chromatin modificationGO:1903310280.012
negative regulation of cell sizeGO:004579230.012
purine nucleoside monophosphate catabolic processGO:0009128580.012
positive regulation of nervous system developmentGO:00519622210.011
regulation of cellular component biogenesisGO:00440871810.011
positive regulation of protein phosphorylationGO:00019342420.011
digestive system developmentGO:00551232000.011
regulation of lymphocyte mediated immunityGO:0002706840.011
regulation of secretionGO:00510462740.011
regulation of lymphocyte activationGO:00512492400.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
negative regulation of protein modification processGO:00314001630.011
negative regulation of mitotic cell cycleGO:0045930580.011
skeletal system developmentGO:00015013560.011
signal transduction by p53 class mediatorGO:0072331510.011
positive regulation of oocyte developmentGO:006028240.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
dephosphorylationGO:00163111290.011
positive regulation of protein modification processGO:00314012990.011
regulation of cell motilityGO:20001452360.011
regulation of secretion by cellGO:19035302490.011
positive regulation of cell cycle phase transitionGO:1901989170.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
regulation of spindle organizationGO:009022420.011
liver developmentGO:0001889660.011
purine ribonucleotide metabolic processGO:00091502900.011
regulation of cellular protein catabolic processGO:1903362610.011
negative regulation of protein depolymerizationGO:1901880210.011
regulation of histone methylationGO:0031060300.011
intracellular protein transportGO:00068862040.011
t cell activationGO:00421102890.011
peptide secretionGO:00027901140.010
mrna processingGO:0006397630.010
cellular macromolecule catabolic processGO:00442652060.010
nucleoside monophosphate metabolic processGO:0009123850.010
maintenance of dna methylationGO:001021640.010
regulation of membrane potentialGO:00423911920.010
positive regulation of mitotic cell cycle phase transitionGO:1901992170.010
atp metabolic processGO:0046034750.010
dna dependent dna replicationGO:0006261240.010
negative regulation of gene expression epigeneticGO:0045814150.010
lymphocyte differentiationGO:00300982420.010
somatic diversification of immunoglobulinsGO:0016445430.010
negative regulation of immune system processGO:00026832090.010
mitotic spindle organizationGO:0007052100.010
sensory perceptionGO:00076002450.010
reciprocal dna recombinationGO:0035825160.010
meiosis iiGO:000713570.010

Eme1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone marrow diseaseDOID:496100.103
hematopoietic system diseaseDOID:7400.103
anemiaDOID:235500.103
congenital hypoplastic anemiaDOID:134200.103
aplastic anemiaDOID:1244900.103
immune system diseaseDOID:291400.103
disease of anatomical entityDOID:700.103
disease of cellular proliferationDOID:1456600.054
cancerDOID:16200.054
organ system cancerDOID:005068600.047
intestinal cancerDOID:1015500.040
gastrointestinal system cancerDOID:311900.040
thoracic cancerDOID:509300.019
nervous system diseaseDOID:86300.016
large intestine cancerDOID:567200.015
fanconi s anemiaDOID:1363600.014
inherited metabolic disorderDOID:65500.014
disease of metabolismDOID:001466700.014
colorectal cancerDOID:925600.013