Mus musculus

31 known processes

Slc22a21

solute carrier family 22 (organic cation transporter), member 21

(Aliases: Octn3,Slc22a9)

Slc22a21 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203610.165
cation transportGO:00068123990.122
nucleoside phosphate metabolic processGO:00067533380.112
purine ribonucleotide metabolic processGO:00091502900.104
transmembrane transportGO:00550854120.095
cellular amino acid metabolic processGO:00065201030.083
cellular amine metabolic processGO:0044106440.078
macromolecule catabolic processGO:00090572810.078
regulation of cellular amino acid metabolic processGO:000652150.077
regulation of hydrolase activityGO:00513362460.075
cellular nitrogen compound catabolic processGO:00442702800.073
positive regulation of cellular catabolic processGO:00313311480.068
anion transmembrane transportGO:0098656710.067
heterocycle catabolic processGO:00467002800.066
protein catabolic processGO:00301632210.063
carboxylic acid transportGO:00469421000.061
organic anion transportGO:00157111370.059
purine nucleoside triphosphate catabolic processGO:00091462030.057
regulation of cellular ketone metabolic processGO:0010565660.057
purine containing compound catabolic processGO:00725232130.057
peptidyl amino acid modificationGO:00181933360.057
regulation of cellular amine metabolic processGO:0033238200.056
ribonucleotide metabolic processGO:00092592910.056
organic cyclic compound catabolic processGO:19013612950.056
nucleotide catabolic processGO:00091662170.055
regulation of cell activationGO:00508652890.054
nucleobase containing small molecule metabolic processGO:00550863520.053
positive regulation of cellular amino acid metabolic processGO:004576430.052
purine ribonucleotide catabolic processGO:00091542080.052
small gtpase mediated signal transductionGO:0007264970.052
amine metabolic processGO:0009308450.051
maintenance of locationGO:0051235890.051
glycosyl compound metabolic processGO:19016572460.051
nucleoside metabolic processGO:00091162460.051
monocarboxylic acid metabolic processGO:00327871910.050
Mouse
purine nucleotide catabolic processGO:00061952110.050
positive regulation of protein modification processGO:00314012990.050
regulation of kinase activityGO:00435492490.049
purine nucleotide metabolic processGO:00061633020.049
nucleoside catabolic processGO:00091642060.049
regulation of ion transportGO:00432692150.049
aromatic compound catabolic processGO:00194392860.049
organic hydroxy compound metabolic processGO:19016152030.049
Mouse
nucleoside phosphate catabolic processGO:19012922220.048
cellular ketone metabolic processGO:0042180840.048
carbohydrate derivative catabolic processGO:19011362310.048
organonitrogen compound catabolic processGO:19015652640.047
nucleoside triphosphate metabolic processGO:00091412300.047
purine ribonucleoside catabolic processGO:00461302050.046
cytoplasmic transportGO:00164822340.046
regulation of secretionGO:00510462740.046
organophosphate catabolic processGO:00464342320.046
regulation of transferase activityGO:00513382630.045
positive regulation of transferase activityGO:00513471670.044
regulation of intracellular transportGO:00323861590.044
cell type specific apoptotic processGO:00972852680.043
positive regulation of kinase activityGO:00336741550.043
regulation of purine nucleotide metabolic processGO:19005421690.042
immune effector processGO:00022523210.042
ribose phosphate metabolic processGO:00196932910.042
membrane organizationGO:00610242450.042
ribonucleoside triphosphate metabolic processGO:00091992200.042
nucleotide metabolic processGO:00091173320.040
purine nucleoside metabolic processGO:00422782410.040
cation transmembrane transportGO:00986552660.039
nucleoside triphosphate catabolic processGO:00091432050.039
glycosyl compound catabolic processGO:19016582060.039
purine containing compound metabolic processGO:00725213110.039
ribonucleoside metabolic processGO:00091192450.038
apoptotic signaling pathwayGO:00971903060.037
innate immune responseGO:00450871570.037
cellular protein catabolic processGO:00442571550.036
protein processingGO:00164851630.036
purine ribonucleoside metabolic processGO:00461282410.036
purine ribonucleoside triphosphate metabolic processGO:00092052200.036
regulation of organelle organizationGO:00330432890.036
cell adhesionGO:00071553290.035
activation of immune responseGO:00022531380.035
amino acid transportGO:0006865610.035
nitrogen compound transportGO:00717052710.035
negative regulation of immune system processGO:00026832090.035
purine nucleoside triphosphate metabolic processGO:00091442260.035
organic hydroxy compound transportGO:0015850930.034
ras protein signal transductionGO:0007265770.034
neuronal action potentialGO:0019228540.034
positive regulation of cellular amine metabolic processGO:003324050.034
cellular macromolecule catabolic processGO:00442652060.034
positive regulation of hydrolase activityGO:00513451480.033
organic acid transportGO:00158491010.033
cell substrate adhesionGO:00315891300.032
sequestering of calcium ionGO:0051208180.032
ribonucleoside catabolic processGO:00424542060.032
leukocyte mediated immunityGO:00024431740.031
divalent inorganic cation transportGO:00725111780.031
multicellular organism growthGO:00352641610.031
sequestering of metal ionGO:0051238190.031
mapk cascadeGO:00001652810.031
single fertilizationGO:0007338820.031
t cell activationGO:00421102890.031
cytokine productionGO:00018163190.031
phospholipid metabolic processGO:0006644870.031
positive regulation of protein kinase activityGO:00458601440.031
regulation of cellular catabolic processGO:00313292420.031
response to organic cyclic compoundGO:00140701980.030
Mouse
protein maturationGO:00516041760.030
regulation of body fluid levelsGO:00508781620.030
purine nucleoside catabolic processGO:00061522050.030
proteolysis involved in cellular protein catabolic processGO:00516031470.030
positive regulation of protein phosphorylationGO:00019342420.030
regulation of lymphocyte activationGO:00512492400.030
wnt signaling pathwayGO:00160551880.030
cell cell recognitionGO:0009988440.030
metal ion homeostasisGO:00550651890.029
regulation of mapk cascadeGO:00434082480.029
sensory perceptionGO:00076002450.029
response to lipopolysaccharideGO:00324961280.029
fertilizationGO:00095661270.029
negative regulation of cellular amino acid metabolic processGO:004576300.029
regulation of nucleotide metabolic processGO:00061401690.028
purine ribonucleoside triphosphate catabolic processGO:00092071990.028
immune response regulating signaling pathwayGO:00027641250.028
negative regulation of molecular functionGO:00440922580.028
muscle system processGO:00030121410.028
modification dependent protein catabolic processGO:00199411330.027
negative regulation of cellular protein metabolic processGO:00322692470.027
spermatogenesisGO:00072832840.027
ribonucleoside triphosphate catabolic processGO:00092031990.027
adaptive immune responseGO:00022501550.027
regulation of protein transportGO:00512231630.026
regulation of purine nucleotide catabolic processGO:00331211220.026
organelle localizationGO:00516401790.026
negative regulation of cellular amine metabolic processGO:003323910.026
response to extracellular stimulusGO:00099911270.026
regulation of cell migrationGO:00303342190.026
inorganic ion transmembrane transportGO:00986602340.025
mitotic cell cycleGO:00002781950.025
exocytosisGO:00068871210.025
negative regulation of cell activationGO:00508661110.025
regulation of cell projection organizationGO:00313442060.025
calcium ion transportGO:00068161590.025
male gamete generationGO:00482322850.025
cellular response to lipidGO:00713961450.025
response to organonitrogen compoundGO:00102432460.025
response to molecule of bacterial originGO:00022371430.025
regulation of nucleotide catabolic processGO:00308111220.025
peptidyl tyrosine phosphorylationGO:00181081430.024
actin cytoskeleton organizationGO:00300362200.024
intracellular protein transportGO:00068862040.024
modification dependent macromolecule catabolic processGO:00436321330.024
peptidyl serine modificationGO:0018209830.024
cellular lipid metabolic processGO:00442553230.024
Mouse
negative regulation of lymphocyte activationGO:0051250910.024
regulation of protein serine threonine kinase activityGO:00719001570.024
cell recognitionGO:0008037830.024
regulation of homeostatic processGO:00328441820.024
Human
regulation of cytoplasmic transportGO:19036491120.024
regulation of ras protein signal transductionGO:00465781140.024
positive regulation of purine nucleotide metabolic processGO:19005441140.023
response to growth factorGO:00708481980.023
regulation of cell cycleGO:00517262810.023
cellular homeostasisGO:00197252400.023
blood circulationGO:00080151950.023
positive regulation of programmed cell deathGO:00430682180.023
regulation of response to woundingGO:19030341890.023
regulation of anatomical structure sizeGO:00900661780.023
regulation of membrane potentialGO:00423911920.022
endomembrane system organizationGO:00102561470.022
lymphocyte differentiationGO:00300982420.022
ribonucleotide catabolic processGO:00092612080.022
regulation of nucleoside metabolic processGO:00091181300.022
organelle assemblyGO:00709251770.021
carbohydrate derivative biosynthetic processGO:19011371830.021
sperm egg recognitionGO:0035036370.021
endocytosisGO:00068971680.021
inflammatory responseGO:00069542440.021
peptidyl tyrosine modificationGO:00182121450.021
transmission of nerve impulseGO:0019226760.021
meiotic cell cycleGO:00513211220.021
response to radiationGO:00093141650.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.021
regulation of cellular response to stressGO:00801351590.021
cellular chemical homeostasisGO:00550822150.020
action potentialGO:0001508780.020
amino acid transmembrane transportGO:0003333370.020
sensory perception of mechanical stimulusGO:00509541070.020
leukocyte differentiationGO:00025213420.020
lipid localizationGO:00108761260.020
gtp catabolic processGO:00061841430.020
meiotic nuclear divisionGO:00071261150.020
rho protein signal transductionGO:0007266320.020
regulation of cellular component biogenesisGO:00440871810.020
sulfur compound metabolic processGO:00067901000.020
regulation of ras gtpase activityGO:0032318880.020
regulation of proteolysisGO:00301621640.020
negative regulation of protein metabolic processGO:00512482820.019
dna repairGO:00062811070.019
regulation of protein kinase activityGO:00458592320.019
circadian regulation of gene expressionGO:0032922480.019
ubiquitin dependent protein catabolic processGO:00065111290.019
calcium ion transmembrane transportGO:0070588850.019
alcohol metabolic processGO:00060661160.019
anion transportGO:00068201770.019
meiotic cell cycle processGO:1903046770.019
inorganic cation transmembrane transportGO:00986622070.019
negative regulation of phosphorylationGO:00423261660.019
organelle fissionGO:00482851700.019
positive regulation of nucleotide metabolic processGO:00459811140.018
positive regulation of ion transportGO:0043270650.018
regulation of endopeptidase activityGO:0052548890.018
regulation of cell adhesionGO:00301551540.018
positive regulation of nucleotide catabolic processGO:0030813880.018
regulation of secretion by cellGO:19035302490.018
regulation of lipid metabolic processGO:00192161180.018
steroid metabolic processGO:00082021190.018
immune response activating signal transductionGO:00027571160.018
regulation of leukocyte mediated immunityGO:00027031040.018
cellular response to dna damage stimulusGO:00069742070.018
leukocyte activation involved in immune responseGO:00023661260.018
positive regulation of purine nucleotide catabolic processGO:0033123880.018
oxidation reduction processGO:00551143420.018
nucleocytoplasmic transportGO:00069131390.018
regulation of establishment of protein localizationGO:00702011810.018
lymphocyte mediated immunityGO:00024491390.018
positive regulation of nucleoside metabolic processGO:0045979910.018
positive regulation of apoptotic processGO:00430652170.018
blood vessel morphogenesisGO:00485142850.018
regulation of t cell activationGO:00508631700.018
lipid biosynthetic processGO:00086101790.018
cellular divalent inorganic cation homeostasisGO:00725031270.018
cation homeostasisGO:00550802120.018
positive regulation of mapk cascadeGO:00434101700.018
microtubule based processGO:00070172360.017
positive regulation of gtpase activityGO:0043547850.017
divalent metal ion transportGO:00708381720.017
meiosis iGO:0007127600.017
dephosphorylationGO:00163111290.017
circulatory system processGO:00030131970.017
development of primary sexual characteristicsGO:00451371430.017
regulation of synaptic growth at neuromuscular junctionGO:000858240.017
regulation of ion transmembrane transportGO:00347651190.017
lymphocyte proliferationGO:00466511640.017
response to nutrient levelsGO:00316671090.017
oocyte axis specificationGO:000730920.017
alpha beta t cell differentiationGO:0046632690.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.017
protein autophosphorylationGO:0046777610.017
wound healingGO:00420601570.017
protein localization to organelleGO:00333651850.017
regulation of apoptotic signaling pathwayGO:20012331970.017
negative regulation of phosphate metabolic processGO:00459361840.017
regulation of gtp catabolic processGO:00331241130.016
sperm motilityGO:0030317470.016
posttranscriptional regulation of gene expressionGO:00106081550.016
regulation of cytokine productionGO:00018172660.016
nuclear divisionGO:00002801580.016
multicellular organismal signalingGO:0035637910.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.016
regulation of innate immune responseGO:0045088910.016
nuclear transportGO:00511691390.016
cellular response to lipopolysaccharideGO:0071222770.016
cell activation involved in immune responseGO:00022631260.016
carbohydrate metabolic processGO:00059752300.016
leukocyte apoptotic processGO:0071887710.016
neuron apoptotic processGO:00514021420.016
regulation of protein localizationGO:00328802310.016
regulation of protein catabolic processGO:00421761080.016
positive regulation of innate immune responseGO:0045089800.016
glycoprotein metabolic processGO:00091001160.016
positive regulation of cell developmentGO:00107202370.016
muscle contractionGO:00069361010.016
negative regulation of phosphorus metabolic processGO:00105631840.016
regulation of ion homeostasisGO:2000021640.015
response to inorganic substanceGO:0010035960.015
Zebrafish
mrna metabolic processGO:0016071840.015
regulation of phospholipase c activityGO:190027430.015
alpha beta t cell activationGO:0046631910.015
axonogenesisGO:00074092740.015
skeletal system developmentGO:00015013560.015
angiogenesisGO:00015252010.015
cellular ion homeostasisGO:00068731650.015
dna metabolic processGO:00062593030.015
response to acid chemicalGO:00011011110.015
anatomical structure homeostasisGO:00602491450.015
Human
binding of sperm to zona pellucidaGO:0007339340.015
positive regulation of gtp catabolic processGO:0033126850.015
positive regulation of defense responseGO:00313491240.015
cellular metal ion homeostasisGO:00068751510.015
locomotory behaviorGO:00076261950.015
positive regulation of cell deathGO:00109422240.015
nuclear importGO:0051170950.015
gonad developmentGO:00084061410.015
peptidyl serine phosphorylationGO:0018105740.014
regulation of defense responseGO:00313472330.014
guanosine containing compound catabolic processGO:19010691440.014
actin filament organizationGO:00070151130.014
regulation of transmembrane transportGO:00347621280.014
male meiosis iGO:0007141160.014
protein secretionGO:00093061110.014
positive regulation of lymphocyte activationGO:00512511400.014
myeloid cell differentiationGO:00300992330.014
female gamete generationGO:0007292740.014
immune response activating cell surface receptor signaling pathwayGO:0002429720.014
regulation of leukocyte proliferationGO:00706631210.014
cytosolic calcium ion transportGO:0060401480.014
regulation of mitotic cell cycle phase transitionGO:1901990730.014
plasma membrane organizationGO:0007009900.014
organonitrogen compound biosynthetic processGO:19015661920.014
positive regulation of protein serine threonine kinase activityGO:00719021060.014
regulation of cell cycle phase transitionGO:1901987770.014
regulation of protein processingGO:0070613960.014
detection of mechanical stimulus involved in sensory perception of painGO:005096640.014
regulation of lymphocyte differentiationGO:00456191070.014
b cell proliferationGO:0042100530.014
positive regulation of proteolysisGO:0045862850.014
sensory perception of soundGO:0007605970.014
nucleoside monophosphate metabolic processGO:0009123850.014
regulation of neurotransmitter levelsGO:0001505870.014
positive regulation of secretionGO:00510471300.014
protein ubiquitinationGO:00165671710.013
cellular response to molecule of bacterial originGO:0071219830.013
germ cell developmentGO:00072811850.013
positive regulation of intracellular transportGO:0032388700.013
t cell differentiationGO:00302171740.013
protein localization to nucleusGO:00345041210.013
positive regulation of ras gtpase activityGO:0032320650.013
positive regulation of phospholipase c activityGO:001086320.013
response to light stimulusGO:00094161350.013
neuron deathGO:00709971540.013
regulation of multi organism processGO:00439001110.013
glycerolipid metabolic processGO:00464861220.013
Mouse
muscle tissue developmentGO:00605373080.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
negative regulation of cellular component organizationGO:00511291940.013
negative regulation of proteolysisGO:0045861740.013
protein modification by small protein conjugation or removalGO:00706472070.013
mitotic cell cycle processGO:19030471590.013
purine ribonucleoside monophosphate metabolic processGO:0009167800.013
tissue remodelingGO:00487711020.013
myeloid cell homeostasisGO:00022621140.013
gland developmentGO:00487323300.013
negative regulation of protein modification processGO:00314001630.013
regulation of leukocyte apoptotic processGO:2000106560.013
positive regulation of organelle organizationGO:00106381280.013
cardiac muscle contractionGO:0060048320.013
leukocyte proliferationGO:00706611720.013
cellular response to organonitrogen compoundGO:00714171450.013
reactive oxygen species metabolic processGO:0072593840.013
negative regulation of protein phosphorylationGO:00019331260.012
blood coagulationGO:0007596760.012
male meiosisGO:0007140370.012
microtubule cytoskeleton organizationGO:00002261570.012
regulation of nucleocytoplasmic transportGO:0046822730.012
fat cell differentiationGO:00454441600.012
regulation of neuron differentiationGO:00456642810.012
single organism cell adhesionGO:00986021560.012
gtp metabolic processGO:00460391440.012
protein modification by small protein conjugationGO:00324461870.012
lymphocyte activation involved in immune responseGO:0002285930.012
proteasomal protein catabolic processGO:0010498980.012
regulation of protein maturationGO:1903317960.012
positive regulation of protein transportGO:0051222930.012
cardiac muscle cell contractionGO:008600370.012
negative regulation of protein processingGO:0010955790.012
release of sequestered calcium ion into cytosolGO:0051209420.012
positive regulation of cytokine productionGO:00018191740.012
negative regulation of leukocyte differentiationGO:1902106510.012
regulation of cellular component sizeGO:00325351210.012
regulation of lymphocyte proliferationGO:00506701170.012
mrna processingGO:0006397630.012
negative regulation of cholesterol transportGO:003237540.012
stem cell differentiationGO:00488632680.012
calcium ion homeostasisGO:00550741270.012
regulation of calcium ion transportGO:0051924690.012
actin filament based movementGO:0030048230.012
developmental maturationGO:00217001930.012
skeletal muscle organ developmentGO:00605381630.011
retrograde transport endosome to golgiGO:004214720.011
substrate adhesion dependent cell spreadingGO:0034446300.011
regulation of cell cycle processGO:00105641600.011
epithelial cell proliferationGO:00506731740.011
forebrain developmentGO:00309003020.011
immune response regulating cell surface receptor signaling pathwayGO:0002768800.011
protein localization to membraneGO:00726571080.011
dna recombinationGO:0006310920.011
positive regulation of phospholipase activityGO:001051830.011
regulation of system processGO:00440572000.011
Human
calcium ion transport into cytosolGO:0060402480.011
multi multicellular organism processGO:00447061090.011
positive regulation of immune effector processGO:00026991070.011
skin developmentGO:00435882200.011
regulation of map kinase activityGO:00434051200.011
transforming growth factor beta receptor signaling pathwayGO:0007179710.011
chromatin organizationGO:00063252060.011
amide transportGO:00428861380.011
adult locomotory behaviorGO:0008344910.011
regulation of cell motilityGO:20001452360.011
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.011
carboxylic acid biosynthetic processGO:0046394860.011
rna processingGO:00063961050.011
regulation of membrane protein ectodomain proteolysisGO:005104330.011
membrane tubulationGO:009732040.011
learning or memoryGO:00076111480.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
cellular response to hormone stimulusGO:00328701500.011
regulation of intracellular protein transportGO:0033157820.011
antigen receptor mediated signaling pathwayGO:0050851640.011
ossificationGO:00015032160.011
axon ensheathmentGO:0008366760.011
organophosphate biosynthetic processGO:00904071220.011
regulation of rho protein signal transductionGO:0035023710.011
positive regulation of nervous system developmentGO:00519622210.011
monocarboxylic acid transportGO:0015718440.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
positive regulation of t cell activationGO:00508701010.011
positive regulation of cell projection organizationGO:0031346950.011
striated muscle contractionGO:0006941450.011
regulation of muscle system processGO:0090257800.011
cognitionGO:00508901490.011
positive regulation of protein export from nucleusGO:004682740.010
intracellular mrna localizationGO:000829840.010
vesicle localizationGO:0051648860.010
regulation of sequence specific dna binding transcription factor activityGO:00510901060.010
adult behaviorGO:00305341350.010
progesterone metabolic processGO:004244840.010
striated muscle tissue developmentGO:00147062930.010
positive regulation of secretion by cellGO:19035321140.010
negative regulation of t cell activationGO:0050868650.010
hexose metabolic processGO:0019318980.010
small molecule biosynthetic processGO:00442831320.010
positive regulation of membrane protein ectodomain proteolysisGO:005104430.010
positive regulation of map kinase activityGO:0043406840.010
jnk cascadeGO:0007254720.010
cell chemotaxisGO:0060326810.010
positive regulation of protein localization to nucleusGO:1900182300.010
regulation of cytokine secretionGO:0050707610.010
cellular calcium ion homeostasisGO:00068741190.010
atp metabolic processGO:0046034750.010
vacuole organizationGO:0007033380.010
guanosine containing compound metabolic processGO:19010681440.010
positive regulation of cell activationGO:00508671580.010
morphogenesis of a branching epitheliumGO:00611381930.010
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.010
spermatid developmentGO:00072861080.010
positive regulation of cell adhesionGO:0045785800.010
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.010

Slc22a21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.025
disease of anatomical entityDOID:700.025
hematopoietic system diseaseDOID:7400.021
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
organ system cancerDOID:005068600.016
connective tissue diseaseDOID:6500.015
musculoskeletal system diseaseDOID:1700.015
bone diseaseDOID:008000100.015
nervous system diseaseDOID:86300.013
disease of metabolismDOID:001466700.012
Human
inherited metabolic disorderDOID:65500.012
Human