IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Krtap16-4

keratin associated protein 16-4

Entrez: 170654
Ensembl: ENSMUSG00000043982
UniProtKB: Q925H7

Process Predictions
Disease Predictions

Krtap16-4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
epidermis development	GO:0008544	187	0.257
regulation of cellular amine metabolic process	GO:0033238	20	0.176
amine metabolic process	GO:0009308	45	0.145
regulation of cellular ketone metabolic process	GO:0010565	66	0.142
skin development	GO:0043588	220	0.132
embryonic placenta development	GO:0001892	98	0.128
transmembrane transport	GO:0055085	412	0.126
molting cycle	GO:0042303	90	0.113
hair cycle	GO:0042633	90	0.113
cellular amino acid metabolic process	GO:0006520	103	0.109
hair follicle development	GO:0001942	85	0.098
organ growth	GO:0035265	117	0.096
cytokine production	GO:0001816	319	0.095
camera type eye development	GO:0043010	266	0.087
hair follicle morphogenesis	GO:0031069	29	0.087
positive regulation of cellular amine metabolic process	GO:0033240	5	0.086
multicellular organismal signaling	GO:0035637	91	0.085
positive regulation of protein modification process	GO:0031401	299	0.084
hematopoietic progenitor cell differentiation	GO:0002244	143	0.082
defense response to other organism	GO:0098542	197	0.080
keratinocyte differentiation	GO:0030216	48	0.079
innate immune response	GO:0045087	157	0.077
negative regulation of defense response	GO:0031348	77	0.076
cellular amine metabolic process	GO:0044106	44	0.076
epidermis morphogenesis	GO:0048730	33	0.075
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.074
cellular ketone metabolic process	GO:0042180	84	0.072
regulation of cellular amino acid metabolic process	GO:0006521	5	0.071
regulation of cytokine production	GO:0001817	266	0.069
negative regulation of cell development	GO:0010721	169	0.067
defense response to bacterium	GO:0042742	119	0.066
cell adhesion	GO:0007155	329	0.063
regulation of defense response	GO:0031347	233	0.061
placenta development	GO:0001890	140	0.061
negative regulation of cell proliferation	GO:0008285	296	0.052
action potential	GO:0001508	78	0.051
regulation of secretion	GO:0051046	274	0.049
extrinsic apoptotic signaling pathway	GO:0097191	126	0.049
regulation of keratinocyte differentiation	GO:0045616	11	0.049
digestive system development	GO:0055123	200	0.048
immune response regulating signaling pathway	GO:0002764	125	0.047
response to molecule of bacterial origin	GO:0002237	143	0.047
wound healing	GO:0042060	157	0.047
skin morphogenesis	GO:0043589	38	0.047
gland development	GO:0048732	330	0.046
fat cell differentiation	GO:0045444	160	0.045
regulation of cell migration	GO:0030334	219	0.045
negative regulation of inflammatory response	GO:0050728	61	0.044
regulation of ion transport	GO:0043269	215	0.044
regulation of protein transport	GO:0051223	163	0.044
cellular response to cytokine stimulus	GO:0071345	189	0.043
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.042
t cell activation	GO:0042110	289	0.042
developmental maturation	GO:0021700	193	0.041
extracellular structure organization	GO:0043062	148	0.041
epithelial cell proliferation	GO:0050673	174	0.040
inflammatory response	GO:0006954	244	0.040
leukocyte differentiation	GO:0002521	342	0.039
regulation of inflammatory response	GO:0050727	147	0.039
regulation of cytoskeleton organization	GO:0051493	122	0.038
anion transport	GO:0006820	177	0.037
regulation of secretion by cell	GO:1903530	249	0.035
calcium ion transport	GO:0006816	159	0.035
regulation of protein localization	GO:0032880	231	0.035
lymphocyte differentiation	GO:0030098	242	0.034
t cell differentiation	GO:0030217	174	0.033
regulation of actin filament based process	GO:0032970	99	0.032
macromolecule catabolic process	GO:0009057	281	0.032
regulation of epithelial cell proliferation	GO:0050678	141	0.032
regulation of establishment of protein localization	GO:0070201	181	0.032
carbohydrate derivative biosynthetic process	GO:1901137	183	0.032
leukocyte proliferation	GO:0070661	172	0.031
positive regulation of growth	GO:0045927	104	0.031
transmission of nerve impulse	GO:0019226	76	0.031
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.031
b cell activation	GO:0042113	161	0.030
regulation of cytokine secretion	GO:0050707	61	0.030
divalent inorganic cation transport	GO:0072511	178	0.030
cell type specific apoptotic process	GO:0097285	268	0.030
striated muscle tissue development	GO:0014706	293	0.030
positive regulation of protein phosphorylation	GO:0001934	242	0.030
ion transmembrane transport	GO:0034220	361	0.029
cell growth	GO:0016049	130	0.029
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	GO:0061350	2	0.029
regulation of organ morphogenesis	GO:2000027	144	0.029
regulation of membrane potential	GO:0042391	192	0.028
protein secretion	GO:0009306	111	0.028
regulation of response to wounding	GO:1903034	189	0.028
positive regulation of nervous system development	GO:0051962	221	0.027
digestive tract morphogenesis	GO:0048546	147	0.027
organic hydroxy compound metabolic process	GO:1901615	203	0.027
morphogenesis of embryonic epithelium	GO:0016331	159	0.027
regulation of cellular component biogenesis	GO:0044087	181	0.027
response to lipopolysaccharide	GO:0032496	128	0.026
epithelial cell development	GO:0002064	159	0.026
cation transmembrane transport	GO:0098655	266	0.026
regulation of protein secretion	GO:0050708	82	0.026
t cell proliferation	GO:0042098	120	0.026
regulation of cell cycle	GO:0051726	281	0.026
regulation of anatomical structure size	GO:0090066	178	0.025
regulation of lymphocyte activation	GO:0051249	240	0.025
axonogenesis	GO:0007409	274	0.025
lymphocyte proliferation	GO:0046651	164	0.025
defense response to gram negative bacterium	GO:0050829	28	0.025
digestive tract development	GO:0048565	190	0.025
regulation of kinase activity	GO:0043549	249	0.025
gastrulation	GO:0007369	116	0.024
positive regulation of cytokine production	GO:0001819	174	0.024
wnt signaling pathway	GO:0016055	188	0.024
regulation of protein kinase activity	GO:0045859	232	0.024
apoptotic signaling pathway	GO:0097190	306	0.024
mesenchymal cell differentiation	GO:0048762	107	0.024
regulation of epidermal cell differentiation	GO:0045604	21	0.024
regulation of innate immune response	GO:0045088	91	0.024
regulation of cell growth	GO:0001558	91	0.024
regulation of mapk cascade	GO:0043408	248	0.024
negative regulation of cellular protein metabolic process	GO:0032269	247	0.024
positive regulation of defense response	GO:0031349	124	0.024
cellular lipid metabolic process	GO:0044255	323	0.023
cell maturation	GO:0048469	127	0.023
response to organonitrogen compound	GO:0010243	246	0.023
regulation of cellular catabolic process	GO:0031329	242	0.023
adaptive immune response	GO:0002250	155	0.023
organic acid transport	GO:0015849	101	0.023
regulation of epidermis development	GO:0045682	33	0.023
negative regulation of phosphorylation	GO:0042326	166	0.023
protein catabolic process	GO:0030163	221	0.022
sequestering of calcium ion	GO:0051208	18	0.022
maintenance of location	GO:0051235	89	0.022
membrane organization	GO:0061024	245	0.022
regulation of renin secretion into blood stream	GO:1900133	4	0.022
chemotaxis	GO:0006935	247	0.021
cellular response to lipid	GO:0071396	145	0.021
developmental growth involved in morphogenesis	GO:0060560	138	0.021
response to extracellular stimulus	GO:0009991	127	0.021
cation transport	GO:0006812	399	0.021
developmental cell growth	GO:0048588	84	0.021
organic anion transport	GO:0015711	137	0.021
tissue remodeling	GO:0048771	102	0.021
response to organic cyclic compound	GO:0014070	198	0.020
carboxylic acid transport	GO:0046942	100	0.020
cell differentiation involved in embryonic placenta development	GO:0060706	26	0.020
regulation of cell adhesion	GO:0030155	154	0.020
spermatogenesis	GO:0007283	284	0.020
muscle tissue development	GO:0060537	308	0.020
divalent metal ion transport	GO:0070838	172	0.020
multi multicellular organism process	GO:0044706	109	0.019
neuronal action potential	GO:0019228	54	0.019
midgut development	GO:0007494	4	0.019
hindbrain development	GO:0030902	128	0.019
negative regulation of keratinocyte differentiation	GO:0045617	4	0.019
detection of stimulus	GO:0051606	84	0.019
response to growth factor	GO:0070848	198	0.019
regulation of actin nucleation	GO:0051125	4	0.019
regulation of transmembrane transport	GO:0034762	128	0.019
mesenchymal cell development	GO:0014031	93	0.019
cardiac chamber development	GO:0003205	108	0.018
muscle cell differentiation	GO:0042692	261	0.018
positive regulation of ion transport	GO:0043270	65	0.018
endocytosis	GO:0006897	168	0.018
chorionic trophoblast cell proliferation	GO:0097360	1	0.018
mitotic cell cycle	GO:0000278	195	0.018
regulation of neuron differentiation	GO:0045664	281	0.018
skeletal system development	GO:0001501	356	0.018
male gamete generation	GO:0048232	285	0.018
respiratory system development	GO:0060541	190	0.017
monocarboxylic acid metabolic process	GO:0032787	191	0.017
activation of immune response	GO:0002253	138	0.017
g protein coupled receptor signaling pathway	GO:0007186	243	0.017
protein localization to membrane	GO:0072657	108	0.017
somatotropin secreting cell development	GO:0060133	2	0.017
cellular response to hormone stimulus	GO:0032870	150	0.017
regulation of ion homeostasis	GO:2000021	64	0.017
regulation of ion transmembrane transport	GO:0034765	119	0.017
fatty acid metabolic process	GO:0006631	121	0.017
glycerolipid metabolic process	GO:0046486	122	0.017
extracellular matrix organization	GO:0030198	147	0.017
cellular response to lipopolysaccharide	GO:0071222	77	0.017
positive regulation of hydrolase activity	GO:0051345	148	0.016
immune response activating signal transduction	GO:0002757	116	0.016
regulation of leukocyte differentiation	GO:1902105	159	0.016
regulation of cellular component size	GO:0032535	121	0.016
leukocyte apoptotic process	GO:0071887	71	0.016
negative regulation of epithelial cell proliferation	GO:0050680	64	0.016
neuron neuron synaptic transmission	GO:0007270	69	0.016
detection of chemical stimulus involved in sensory perception of smell	GO:0050911	4	0.015
regulation of protein complex assembly	GO:0043254	83	0.015
regulation of t cell proliferation	GO:0042129	92	0.015
regulation of organ growth	GO:0046620	61	0.015
forebrain development	GO:0030900	302	0.015
mapk cascade	GO:0000165	281	0.015
sensory perception	GO:0007600	245	0.015
ras protein signal transduction	GO:0007265	77	0.015
muscle system process	GO:0003012	141	0.015
regulation of cell activation	GO:0050865	289	0.015
negative regulation of immune system process	GO:0002683	209	0.015
endocrine system development	GO:0035270	98	0.015
sequestering of metal ion	GO:0051238	19	0.015
negative regulation of cellular component organization	GO:0051129	194	0.015
ensheathment of neurons	GO:0007272	76	0.015
regulation of map kinase activity	GO:0043405	120	0.015
response to tumor necrosis factor	GO:0034612	26	0.015
cerebral cortex cell migration	GO:0021795	44	0.015
cytokine secretion	GO:0050663	72	0.015
regulation of organelle organization	GO:0033043	289	0.014
bmp signaling pathway	GO:0030509	93	0.014
cellular protein complex assembly	GO:0043623	116	0.014
biomineral tissue development	GO:0031214	64	0.014
cell communication by chemical coupling	GO:0010643	2	0.014
lymphocyte activation involved in immune response	GO:0002285	93	0.014
ossification	GO:0001503	216	0.014
regulation of lymphocyte proliferation	GO:0050670	117	0.014
regulation of transferase activity	GO:0051338	263	0.014
aromatic compound catabolic process	GO:0019439	286	0.014
positive regulation of cellular component biogenesis	GO:0044089	94	0.014
axon ensheathment	GO:0008366	76	0.014
regulation of metal ion transport	GO:0010959	106	0.014
cytoplasmic transport	GO:0016482	234	0.014
positive regulation of cell motility	GO:2000147	116	0.014
nucleoside phosphate metabolic process	GO:0006753	338	0.014
cellular ion homeostasis	GO:0006873	165	0.014
actin filament organization	GO:0007015	113	0.014
defense response to gram positive bacterium	GO:0050830	50	0.014
regulation of fat cell differentiation	GO:0045598	81	0.014
immune effector process	GO:0002252	321	0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.014
purine nucleotide metabolic process	GO:0006163	302	0.014
regulation of bmp signaling pathway	GO:0030510	60	0.014
positive regulation of secretion	GO:0051047	130	0.014
water homeostasis	GO:0030104	27	0.014
hepatocyte apoptotic process	GO:0097284	11	0.014
cellular response to molecule of bacterial origin	GO:0071219	83	0.013
regulation of nucleotide metabolic process	GO:0006140	169	0.013
regulation of adaptive immune response	GO:0002819	90	0.013
intermediate filament based process	GO:0045103	27	0.013
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.013
sensory perception of chemical stimulus	GO:0007606	51	0.013
intrinsic apoptotic signaling pathway	GO:0097193	132	0.013
metencephalon development	GO:0022037	89	0.013
cell fate specification	GO:0001708	72	0.013
positive regulation of mapk cascade	GO:0043410	170	0.013
regulation of hydrolase activity	GO:0051336	246	0.013
intermediate filament cytoskeleton organization	GO:0045104	26	0.013
cell recognition	GO:0008037	83	0.013
regulation of cell motility	GO:2000145	236	0.013
positive regulation of cellular catabolic process	GO:0031331	148	0.013
neuron migration	GO:0001764	122	0.013
cell activation involved in immune response	GO:0002263	126	0.013
regulation of b cell tolerance induction	GO:0002661	2	0.013
neural precursor cell proliferation	GO:0061351	121	0.013
intracellular protein transport	GO:0006886	204	0.013
leukocyte activation involved in immune response	GO:0002366	126	0.013
intermediate filament organization	GO:0045109	15	0.013
regulation of feeding behavior	GO:0060259	3	0.013
embryonic nail plate morphogenesis	GO:0035880	3	0.013
regulation of purine nucleotide metabolic process	GO:1900542	169	0.013
negative regulation of molecular function	GO:0044092	258	0.013
regulation of leukocyte apoptotic process	GO:2000106	56	0.013
response to nutrient levels	GO:0031667	109	0.013
regulation of actin cytoskeleton organization	GO:0032956	84	0.013
telencephalon cell migration	GO:0022029	55	0.012
lipid transport	GO:0006869	98	0.012
negative regulation of phosphorus metabolic process	GO:0010563	184	0.012
lens development in camera type eye	GO:0002088	62	0.012
stem cell differentiation	GO:0048863	268	0.012
cellular response to biotic stimulus	GO:0071216	92	0.012
neuron projection extension	GO:1990138	64	0.012
response to pain	GO:0048265	26	0.012
regulation of t cell activation	GO:0050863	170	0.012
positive regulation of lymphocyte activation	GO:0051251	140	0.012
protein localization to organelle	GO:0033365	185	0.012
cellular chemical homeostasis	GO:0055082	215	0.012
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.012
leukocyte chemotaxis	GO:0030595	69	0.012
cell fate commitment involved in formation of primary germ layer	GO:0060795	26	0.012
somatotropin secreting cell differentiation	GO:0060126	4	0.012
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.012
small gtpase mediated signal transduction	GO:0007264	97	0.012
tube formation	GO:0035148	140	0.012
cellular homeostasis	GO:0019725	240	0.012
cellular nitrogen compound catabolic process	GO:0044270	280	0.012
forebrain cell migration	GO:0021885	58	0.012
cardiac muscle tissue development	GO:0048738	130	0.012
ventricular septum development	GO:0003281	42	0.012
positive regulation of programmed cell death	GO:0043068	218	0.012
actin polymerization or depolymerization	GO:0008154	54	0.012
i kappab kinase nf kappab signaling	GO:0007249	85	0.012
response to acid chemical	GO:0001101	111	0.012
development of primary female sexual characteristics	GO:0046545	73	0.011
posttranscriptional regulation of gene expression	GO:0010608	155	0.011
carbohydrate derivative catabolic process	GO:1901136	231	0.011
organic hydroxy compound biosynthetic process	GO:1901617	77	0.011
actin filament polymerization	GO:0030041	44	0.011
response to radiation	GO:0009314	165	0.011
small molecule biosynthetic process	GO:0044283	132	0.011
regulation of lymphocyte differentiation	GO:0045619	107	0.011
regulation of calcium ion transport	GO:0051924	69	0.011
neural tube closure	GO:0001843	90	0.011
telencephalon development	GO:0021537	186	0.011
regulation of muscle tissue development	GO:1901861	97	0.011
blood vessel remodeling	GO:0001974	33	0.011
organic cyclic compound catabolic process	GO:1901361	295	0.011
regulation of wnt signaling pathway	GO:0030111	123	0.011
reactive oxygen species metabolic process	GO:0072593	84	0.011
neuromuscular process	GO:0050905	99	0.011
establishment of planar polarity of embryonic epithelium	GO:0042249	16	0.011
organic acid biosynthetic process	GO:0016053	86	0.011
connective tissue development	GO:0061448	179	0.011
heterocycle catabolic process	GO:0046700	280	0.011
planar cell polarity pathway involved in cardiac right atrium morphogenesis	GO:0061349	2	0.011
cellular metal ion homeostasis	GO:0006875	151	0.011
defecation	GO:0030421	1	0.011
positive regulation of protein complex assembly	GO:0031334	45	0.011
response to peptide hormone	GO:0043434	127	0.011
regulation of protein catabolic process	GO:0042176	108	0.011
development of primary male sexual characteristics	GO:0046546	88	0.011
membrane depolarization	GO:0051899	64	0.011
embryonic limb morphogenesis	GO:0030326	126	0.010
nitrogen compound transport	GO:0071705	271	0.010
regulation of reproductive process	GO:2000241	66	0.010
positive regulation of cell cycle	GO:0045787	92	0.010
glycoprotein metabolic process	GO:0009100	116	0.010
positive regulation of epithelial cell proliferation	GO:0050679	68	0.010
regulation of mitotic cell cycle	GO:0007346	126	0.010
positive regulation of innate immune response	GO:0045089	80	0.010
antigen receptor mediated signaling pathway	GO:0050851	64	0.010
development of primary sexual characteristics	GO:0045137	143	0.010
cellular response to abiotic stimulus	GO:0071214	56	0.010
regulation of action potential	GO:0098900	4	0.010
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	GO:0014834	3	0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	61	0.010
positive regulation of map kinase activity	GO:0043406	84	0.010
gonad development	GO:0008406	141	0.010
epithelial tube morphogenesis	GO:0060562	303	0.010
urogenital system development	GO:0001655	261	0.010
purine ribonucleotide catabolic process	GO:0009154	208	0.010
protein maturation	GO:0051604	176	0.010
t cell receptor signaling pathway	GO:0050852	46	0.010
mesodermal cell migration	GO:0008078	4	0.010
purine nucleoside metabolic process	GO:0042278	241	0.010
negative regulation of mitotic cell cycle	GO:0045930	58	0.010
cardiac septum development	GO:0003279	59	0.010
angiogenesis	GO:0001525	201	0.010
response to inorganic substance	GO:0010035	96	0.010
negative regulation of response to wounding	GO:1903035	77	0.010
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.010

Krtap16-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	musculoskeletal system disease	DOID:17	0	0.012
	disease of anatomical entity	DOID:7	0	0.012

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