IMP: Integrative Multi-species Prediction

Mus musculus

9 known processes

Gdf10

growth differentiation factor 10

Entrez: 14560
Ensembl: ENSMUSG00000021943
UniProtKB: P97737

Process Predictions
Disease Predictions

Gdf10 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of hormone levels	GO:0010817	211	0.342
regulation of cell adhesion	GO:0030155	154	0.305
cell adhesion	GO:0007155	329	0.281
gland development	GO:0048732	330	0.280	Mouse
extracellular matrix organization	GO:0030198	147	0.244
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	GO:0014834	3	0.234
developmental growth involved in morphogenesis	GO:0060560	138	0.219
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.213	Mouse
axonogenesis	GO:0007409	274	0.207	Mouse
limb morphogenesis	GO:0035108	149	0.202	Mouse
morphogenesis of a branching epithelium	GO:0061138	193	0.178	Mouse
urogenital system development	GO:0001655	261	0.175	Mouse
hormone metabolic process	GO:0042445	86	0.168
sensory perception	GO:0007600	245	0.152
spinal cord development	GO:0021510	81	0.151	Mouse
prostate gland morphogenesis	GO:0060512	32	0.149	Mouse
kidney development	GO:0001822	213	0.149	Mouse
type b pancreatic cell proliferation	GO:0044342	10	0.140
skeletal system development	GO:0001501	356	0.138	Mouse
sensory organ morphogenesis	GO:0090596	242	0.138	Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	61	0.134
maintenance of cell number	GO:0098727	3	0.132
muscle tissue development	GO:0060537	308	0.128	Mouse
negative regulation of bmp signaling pathway	GO:0030514	35	0.124
cellular ketone metabolic process	GO:0042180	84	0.119
regulation of cell migration	GO:0030334	219	0.118
positive regulation of nervous system development	GO:0051962	221	0.118	Mouse
regulation of mapk cascade	GO:0043408	248	0.116	Mouse
negative regulation of cell proliferation	GO:0008285	296	0.115	Mouse
negative regulation of catenin import into nucleus	GO:0035414	2	0.114
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.114	Mouse
regulation of epithelial cell proliferation	GO:0050678	141	0.113	Mouse
bmp signaling pathway	GO:0030509	93	0.113	Mouse
regulation of organ morphogenesis	GO:2000027	144	0.112	Mouse
negative regulation of molecular function	GO:0044092	258	0.110
embryonic limb morphogenesis	GO:0030326	126	0.108	Mouse
cell growth	GO:0016049	130	0.107
ion transmembrane transport	GO:0034220	361	0.106
single organism cell adhesion	GO:0098602	156	0.105
regulation of cell growth	GO:0001558	91	0.105
mesonephric duct morphogenesis	GO:0072180	4	0.103
transmembrane transport	GO:0055085	412	0.102
cellular response to growth factor stimulus	GO:0071363	197	0.098	Mouse
inorganic ion transmembrane transport	GO:0098660	234	0.097
midgut development	GO:0007494	4	0.095
regulation of glucose metabolic process	GO:0010906	60	0.095
morphogenesis of a branching structure	GO:0001763	203	0.093	Mouse
cell substrate adhesion	GO:0031589	130	0.092
syncytiotrophoblast cell differentiation involved in labyrinthine layer development	GO:0060715	2	0.092
wound healing	GO:0042060	157	0.090
stem cell proliferation	GO:0072089	117	0.087	Mouse
digestive tract development	GO:0048565	190	0.086	Mouse
endothelial cell apoptotic process	GO:0072577	9	0.085
mitotic cell cycle	GO:0000278	195	0.084
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.083
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.082	Mouse
connective tissue development	GO:0061448	179	0.082	Mouse
negative regulation of cell migration	GO:0030336	59	0.081
regulation of anatomical structure size	GO:0090066	178	0.080
cellular response to lipid	GO:0071396	145	0.080
regulation of chemotaxis	GO:0050920	53	0.077
regulation of cell substrate adhesion	GO:0010810	73	0.076
positive regulation of cellular amine metabolic process	GO:0033240	5	0.076
germ cell development	GO:0007281	185	0.074	Mouse
hair cycle	GO:0042633	90	0.074
negative regulation of hydrolase activity	GO:0051346	71	0.073
striated muscle tissue development	GO:0014706	293	0.071	Mouse
developmental cell growth	GO:0048588	84	0.070
negative regulation of prostatic bud formation	GO:0060686	4	0.069	Mouse
regulation of cell projection organization	GO:0031344	206	0.069
regulation of system process	GO:0044057	200	0.069	Mouse
response to growth factor	GO:0070848	198	0.069	Mouse Rat
negative regulation of epithelial cell proliferation	GO:0050680	64	0.068
positive regulation of cell development	GO:0010720	237	0.068	Mouse
regulation of fat cell differentiation	GO:0045598	81	0.068
blood vessel morphogenesis	GO:0048514	285	0.067	Mouse
kidney epithelium development	GO:0072073	121	0.067	Mouse
cartilage development	GO:0051216	140	0.065	Mouse
cellular response to organic cyclic compound	GO:0071407	87	0.065
inorganic cation transmembrane transport	GO:0098662	207	0.064
cation transmembrane transport	GO:0098655	266	0.064
renal system development	GO:0072001	225	0.064	Mouse
retina development in camera type eye	GO:0060041	119	0.064
response to organic cyclic compound	GO:0014070	198	0.064
bone development	GO:0060348	120	0.064	Mouse
negative regulation of mesenchymal cell proliferation	GO:0072201	3	0.064
embryonic skeletal system development	GO:0048706	120	0.064	Mouse
negative regulation of growth	GO:0045926	99	0.063
blood circulation	GO:0008015	195	0.063
regulation of bmp signaling pathway	GO:0030510	60	0.063
lung development	GO:0030324	164	0.063	Mouse
negative regulation of cell motility	GO:2000146	61	0.063
ear development	GO:0043583	200	0.062
camera type eye development	GO:0043010	266	0.062	Mouse
appendage development	GO:0048736	166	0.062	Mouse
retinal blood vessel morphogenesis	GO:0061304	3	0.062
regulation of cartilage development	GO:0061035	44	0.061	Mouse
cell division	GO:0051301	120	0.061
hexose metabolic process	GO:0019318	98	0.059
tissue remodeling	GO:0048771	102	0.058
response to transforming growth factor beta	GO:0071559	88	0.058	Mouse Rat
ureteric bud development	GO:0001657	94	0.058	Mouse
negative regulation of hepatocyte differentiation	GO:0070367	1	0.058
angiogenesis	GO:0001525	201	0.058	Mouse
appendage morphogenesis	GO:0035107	149	0.057	Mouse
muscle system process	GO:0003012	141	0.057	Mouse
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.055
regulation of ketone biosynthetic process	GO:0010566	2	0.055
regulation of cell motility	GO:2000145	236	0.055
positive regulation of cell adhesion	GO:0045785	80	0.054
cytokine production	GO:0001816	319	0.054
prostate gland development	GO:0030850	48	0.053	Mouse
neural precursor cell proliferation	GO:0061351	121	0.053
digestive tract morphogenesis	GO:0048546	147	0.052	Mouse
monocarboxylic acid metabolic process	GO:0032787	191	0.052
limb development	GO:0060173	166	0.052	Mouse
small gtpase mediated signal transduction	GO:0007264	97	0.051
cation transport	GO:0006812	399	0.050
forebrain morphogenesis	GO:0048853	17	0.050	Mouse
embryonic organ morphogenesis	GO:0048562	276	0.049	Mouse
negative regulation of endothelial cell apoptotic process	GO:2000352	7	0.049
cellular amino acid metabolic process	GO:0006520	103	0.048
trabecula formation	GO:0060343	24	0.048	Mouse
cellular response to organonitrogen compound	GO:0071417	145	0.048
regulation of chorionic trophoblast cell proliferation	GO:1901382	1	0.048
muscle cell differentiation	GO:0042692	261	0.048	Mouse
positive regulation of cell substrate adhesion	GO:0010811	47	0.047
coagulation	GO:0050817	78	0.047
mesonephric epithelium development	GO:0072163	94	0.047	Mouse
cardiac muscle tissue growth	GO:0055017	37	0.047	Mouse
negative regulation of protein metabolic process	GO:0051248	282	0.046
protein localization to nucleus	GO:0034504	121	0.046
skin morphogenesis	GO:0043589	38	0.046
cardiac chamber morphogenesis	GO:0003206	93	0.045	Mouse
cerebellum vasculature development	GO:0061300	1	0.045
progesterone secretion	GO:0042701	1	0.045
regulation of endothelial cell apoptotic process	GO:2000351	9	0.045
regulation of kinase activity	GO:0043549	249	0.045
monosaccharide transport	GO:0015749	58	0.045
regulation of map kinase activity	GO:0043405	120	0.045
hemostasis	GO:0007599	78	0.045
female sex differentiation	GO:0046660	84	0.045
hematopoietic stem cell proliferation	GO:0071425	13	0.044
sensory perception of mechanical stimulus	GO:0050954	107	0.044
regulation of blood pressure	GO:0008217	93	0.044
cellular response to hormone stimulus	GO:0032870	150	0.044
apoptotic signaling pathway	GO:0097190	306	0.044
epidermis development	GO:0008544	187	0.044
hexose biosynthetic process	GO:0019319	39	0.044
protein localization to organelle	GO:0033365	185	0.044
forebrain development	GO:0030900	302	0.044	Mouse
glucose metabolic process	GO:0006006	92	0.044
regulation of proteolysis	GO:0030162	164	0.044
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.043
positive regulation of cell cell adhesion mediated by cadherin	GO:2000049	2	0.043
mesonephric tubule morphogenesis	GO:0072171	63	0.043
pallium development	GO:0021543	120	0.043
positive regulation of neuron differentiation	GO:0045666	141	0.043	Mouse
lung morphogenesis	GO:0060425	50	0.043	Mouse
positive regulation of neuron projection development	GO:0010976	79	0.043
canonical wnt signaling pathway	GO:0060070	130	0.042
hair follicle development	GO:0001942	85	0.042
glucose homeostasis	GO:0042593	128	0.042
polarity specification of proximal distal axis	GO:0010085	2	0.042	Mouse
defense response to bacterium	GO:0042742	119	0.042
regulation of body fluid levels	GO:0050878	162	0.041
fat cell differentiation	GO:0045444	160	0.041
embryonic appendage morphogenesis	GO:0035113	126	0.041	Mouse
regulation of protein kinase b signaling	GO:0051896	56	0.041
wnt signaling pathway	GO:0016055	188	0.041
negative regulation of execution phase of apoptosis	GO:1900118	4	0.040
metencephalon development	GO:0022037	89	0.040	Rat
ureteric bud morphogenesis	GO:0060675	62	0.040
digestive system development	GO:0055123	200	0.040	Mouse
transmission of nerve impulse	GO:0019226	76	0.040
regulation of cellular ketone metabolic process	GO:0010565	66	0.040
response to organonitrogen compound	GO:0010243	246	0.040
regulation of biomineral tissue development	GO:0070167	33	0.040
regulation of ossification	GO:0030278	112	0.040	Rat
regulation of ion transport	GO:0043269	215	0.039
epithelial tube morphogenesis	GO:0060562	303	0.039	Mouse
platelet activation	GO:0030168	40	0.039
nephron morphogenesis	GO:0072028	69	0.039	Mouse
positive regulation of cell projection organization	GO:0031346	95	0.039
nephron development	GO:0072006	109	0.039	Mouse
carbohydrate homeostasis	GO:0033500	128	0.039
trachea cartilage morphogenesis	GO:0060535	4	0.039
cellular lipid metabolic process	GO:0044255	323	0.038
organ growth	GO:0035265	117	0.038	Mouse
branching morphogenesis of an epithelial tube	GO:0048754	159	0.038	Mouse
negative regulation of transforming growth factor beta receptor signaling pathway	GO:0030512	26	0.038
embryonic skeletal system morphogenesis	GO:0048704	91	0.038	Mouse
positive regulation of protein phosphorylation	GO:0001934	242	0.037	Mouse
multicellular organismal homeostasis	GO:0048871	164	0.037	Mouse
fatty acid metabolic process	GO:0006631	121	0.037
skeletal muscle organ development	GO:0060538	163	0.037
regulation of protein transport	GO:0051223	163	0.037
cardiac septum morphogenesis	GO:0060411	46	0.036
positive regulation of cell growth	GO:0030307	33	0.036
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.035
ossification	GO:0001503	216	0.035	Mouse Rat
biomineral tissue development	GO:0031214	64	0.035
positive regulation of cell death	GO:0010942	224	0.035	Mouse
multicellular organismal signaling	GO:0035637	91	0.035
skeletal system morphogenesis	GO:0048705	203	0.035	Mouse
potassium ion transmembrane transport	GO:0071805	43	0.034
regulation of cellular amino acid metabolic process	GO:0006521	5	0.034
negative regulation of cell substrate adhesion	GO:0010812	16	0.034
negative regulation of cell adhesion	GO:0007162	45	0.034
negative regulation of osteoblast differentiation	GO:0045668	30	0.034
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.034
mitotic cell cycle process	GO:1903047	159	0.034
protein targeting	GO:0006605	143	0.034
mapk cascade	GO:0000165	281	0.033	Mouse
glucose transport	GO:0015758	56	0.033
cellular response to cytokine stimulus	GO:0071345	189	0.033
regulation of neuron projection development	GO:0010975	169	0.033
primary neural tube formation	GO:0014020	95	0.033	Mouse
skin development	GO:0043588	220	0.033
positive regulation of programmed cell death	GO:0043068	218	0.033	Mouse
regulation of protein localization	GO:0032880	231	0.033
protein oligomerization	GO:0051259	67	0.033
regulation of transmembrane transport	GO:0034762	128	0.033
neuron projection extension	GO:1990138	64	0.033
positive regulation of receptor activity	GO:2000273	17	0.033	Mouse
homeostasis of number of cells	GO:0048872	210	0.033
negative regulation of mitotic cell cycle embryonic	GO:0045976	2	0.032
lateral line system development	GO:0048925	1	0.032
establishment of protein localization to organelle	GO:0072594	118	0.032
muscle cell development	GO:0055001	133	0.032	Mouse
gastrulation	GO:0007369	116	0.032	Mouse
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.032
learning or memory	GO:0007611	148	0.032
metanephric loop of henle development	GO:0072236	4	0.032
establishment of planar polarity of embryonic epithelium	GO:0042249	16	0.032
cerebellum vasculature morphogenesis	GO:0061301	1	0.032
odontogenesis	GO:0042476	78	0.032	Mouse
palate development	GO:0060021	76	0.031
regulation of establishment of protein localization	GO:0070201	181	0.031
negative regulation of protein processing	GO:0010955	79	0.031
defense response to other organism	GO:0098542	197	0.031
chondrocyte differentiation	GO:0002062	72	0.031	Mouse
regulation of transferase activity	GO:0051338	263	0.031
adult behavior	GO:0030534	135	0.031
blood coagulation	GO:0007596	76	0.031
regulation of cellular response to stress	GO:0080135	159	0.030
regulation of protein kinase activity	GO:0045859	232	0.030
response to acid chemical	GO:0001101	111	0.030
regulation of cell cycle	GO:0051726	281	0.030
cerebellar granular layer development	GO:0021681	13	0.029
monosaccharide metabolic process	GO:0005996	106	0.029
positive regulation of anagen	GO:0051885	1	0.029
ear morphogenesis	GO:0042471	118	0.029
nuclear import	GO:0051170	95	0.029
locomotory behavior	GO:0007626	195	0.028
positive regulation of apoptotic process	GO:0043065	217	0.028	Mouse
regulation of hydrolase activity	GO:0051336	246	0.028
embryonic nail plate morphogenesis	GO:0035880	3	0.028
regulation of intracellular protein transport	GO:0033157	82	0.028
regulation of neuron differentiation	GO:0045664	281	0.028	Mouse
positive regulation of protein kinase b signaling	GO:0051897	32	0.028
regulation of cellular amine metabolic process	GO:0033238	20	0.028
tissue homeostasis	GO:0001894	115	0.028
negative regulation of ossification	GO:0030279	49	0.028
branching involved in ureteric bud morphogenesis	GO:0001658	56	0.028
axon guidance	GO:0007411	141	0.028	Mouse
regulation of protein import into nucleus	GO:0042306	52	0.028
leukocyte apoptotic process	GO:0071887	71	0.027
oligodendrocyte differentiation	GO:0048709	53	0.027
renal tubule development	GO:0061326	87	0.027
negative regulation of gastrulation	GO:2000542	3	0.027
negative regulation of phospholipase activity	GO:0010519	4	0.027
extracellular structure organization	GO:0043062	148	0.027
regulation of protein targeting	GO:1903533	61	0.027
cerebellum development	GO:0021549	77	0.027	Rat
cardiac septum development	GO:0003279	59	0.026
cerebellum morphogenesis	GO:0021587	42	0.026
tube formation	GO:0035148	140	0.026	Mouse
neuron projection guidance	GO:0097485	141	0.026	Mouse
positive regulation of transferase activity	GO:0051347	167	0.025
telencephalon development	GO:0021537	186	0.025
regulation of vasculature development	GO:1901342	88	0.025	Mouse
regulation of reproductive process	GO:2000241	66	0.025	Mouse
regulation of cell cycle process	GO:0010564	160	0.025
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.025
single organism nuclear import	GO:1902593	95	0.025
establishment of planar polarity involved in neural tube closure	GO:0090177	15	0.025
protein maturation	GO:0051604	176	0.025
regulation of cytoplasmic transport	GO:1903649	112	0.025
chemotaxis	GO:0006935	247	0.025	Mouse
renal system process	GO:0003014	48	0.024
cell proliferation in midbrain	GO:0033278	2	0.024
cardiac ventricle morphogenesis	GO:0003208	50	0.024	Mouse
regulation of protein secretion	GO:0050708	82	0.024
molting cycle	GO:0042303	90	0.024
myeloid cell differentiation	GO:0030099	233	0.024
carbohydrate metabolic process	GO:0005975	230	0.024
male gamete generation	GO:0048232	285	0.024	Mouse
cell fate commitment	GO:0045165	210	0.024	Mouse
reactive nitrogen species metabolic process	GO:2001057	0	0.024
positive regulation of insulin like growth factor receptor signaling pathway	GO:0043568	8	0.024
g protein coupled receptor signaling pathway	GO:0007186	243	0.024
smoothened signaling pathway	GO:0007224	105	0.024
myeloid leukocyte differentiation	GO:0002573	119	0.024
protein kinase b signaling	GO:0043491	74	0.024
negative regulation of cellular response to growth factor stimulus	GO:0090288	46	0.023
nitrogen compound transport	GO:0071705	271	0.023
regulation of extent of cell growth	GO:0061387	52	0.023
jnk cascade	GO:0007254	72	0.023
t cell differentiation in thymus	GO:0033077	77	0.023
regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045898	2	0.023
synaptic transmission	GO:0007268	329	0.023
regulation of catenin import into nucleus	GO:0035412	5	0.023
cell matrix adhesion	GO:0007160	68	0.023
regulation of smoothened signaling pathway	GO:0008589	58	0.023
nephron tubule development	GO:0072080	84	0.023
cognition	GO:0050890	149	0.023
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation	GO:0044343	1	0.023
regulation of leukocyte apoptotic process	GO:2000106	56	0.023
negative regulation of hormone metabolic process	GO:0032351	4	0.023
positive regulation of cell cycle	GO:0045787	92	0.022
physiological cardiac muscle hypertrophy	GO:0003301	3	0.022
regulation of angiogenesis	GO:0045765	81	0.022	Mouse
protein processing	GO:0016485	163	0.022
metal ion homeostasis	GO:0055065	189	0.022	Mouse
regulation of protein serine threonine kinase activity	GO:0071900	157	0.022
carbohydrate transport	GO:0008643	62	0.022
bone morphogenesis	GO:0060349	78	0.022	Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090100	43	0.022	Mouse
epithelial tube formation	GO:0072175	130	0.022	Mouse
regulation of stem cell proliferation	GO:0072091	78	0.022
renal outer medulla development	GO:0072054	2	0.022
regulation of ion transmembrane transport	GO:0034765	119	0.022
organelle fission	GO:0048285	170	0.022
establishment of planar polarity	GO:0001736	28	0.022
negative regulation of reproductive process	GO:2000242	31	0.022	Mouse
multicellular organism growth	GO:0035264	161	0.022	Mouse
cellular amine metabolic process	GO:0044106	44	0.021
rhythmic process	GO:0048511	174	0.021	Rat
regulation of establishment of planar polarity	GO:0090175	28	0.021
nucleoside triphosphate catabolic process	GO:0009143	205	0.021
t cell differentiation	GO:0030217	174	0.021
endomembrane system organization	GO:0010256	147	0.021
nephron epithelium morphogenesis	GO:0072088	68	0.021
reactive oxygen species metabolic process	GO:0072593	84	0.021
establishment of tissue polarity	GO:0007164	28	0.021
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.021	Mouse
heart growth	GO:0060419	45	0.021	Mouse
intracellular protein transport	GO:0006886	204	0.021
lipid localization	GO:0010876	126	0.021
wnt signaling pathway involved in forebrain neuroblast division	GO:0021874	2	0.021
odontogenesis of dentin containing tooth	GO:0042475	66	0.021	Mouse
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	43	0.020
development of primary female sexual characteristics	GO:0046545	73	0.020
regulation of vesicle mediated transport	GO:0060627	139	0.020
tissue regeneration	GO:0042246	22	0.020
mesonephric tubule development	GO:0072164	94	0.020	Mouse
planar cell polarity pathway involved in ventricular septum morphogenesis	GO:0061348	2	0.020
kidney morphogenesis	GO:0060993	83	0.020	Mouse
cerebellar cortex morphogenesis	GO:0021696	32	0.020
positive regulation of growth	GO:0045927	104	0.020	Mouse
hematopoietic stem cell migration	GO:0035701	1	0.020
negative regulation of cartilage development	GO:0061037	17	0.020
vascular process in circulatory system	GO:0003018	62	0.020
t cell activation	GO:0042110	289	0.020
respiratory system development	GO:0060541	190	0.020	Mouse
chorionic trophoblast cell proliferation	GO:0097360	1	0.020
single organismal cell cell adhesion	GO:0016337	131	0.019
macromolecule catabolic process	GO:0009057	281	0.019
regulation of fatty acid metabolic process	GO:0019217	28	0.019
nephron tubule morphogenesis	GO:0072078	68	0.019
axis elongation involved in somitogenesis	GO:0090245	4	0.019
prostate gland epithelium morphogenesis	GO:0060740	31	0.019	Mouse
regulation of establishment of planar polarity involved in neural tube closure	GO:0090178	15	0.019
protein import	GO:0017038	101	0.019
ubiquitin dependent smad protein catabolic process	GO:0030579	2	0.019
negative regulation of immune system process	GO:0002683	209	0.019
cell type specific apoptotic process	GO:0097285	268	0.019	Mouse
metanephric nephron development	GO:0072210	34	0.019
hormone secretion	GO:0046879	128	0.019
cellular response to external stimulus	GO:0071496	88	0.019
tube closure	GO:0060606	91	0.019
positive regulation of fat cell differentiation	GO:0045600	32	0.019
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation	GO:2000079	1	0.019
regulation of tube size	GO:0035150	57	0.019
regulation of axon extension	GO:0030516	43	0.019
cardiac chamber development	GO:0003205	108	0.019	Mouse
inner ear morphogenesis	GO:0042472	101	0.019
wnt signaling pathway planar cell polarity pathway	GO:0060071	27	0.019
mesonephros development	GO:0001823	97	0.019	Mouse
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.019
meiotic cell cycle	GO:0051321	122	0.019
positive regulation of nucleocytoplasmic transport	GO:0046824	30	0.018
chemokine mediated signaling pathway	GO:0070098	17	0.018
homotypic cell cell adhesion	GO:0034109	28	0.018
response to peptide	GO:1901652	136	0.018
response to inorganic substance	GO:0010035	96	0.018
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.018
regulation of lipid metabolic process	GO:0019216	118	0.018
respiratory tube development	GO:0030323	167	0.018	Mouse
regulation of monocyte chemotaxis	GO:0090025	3	0.018
negative regulation of cellular protein metabolic process	GO:0032269	247	0.018
negative regulation of hormone biosynthetic process	GO:0032353	4	0.018
lymphocyte differentiation	GO:0030098	242	0.018
inner medullary collecting duct development	GO:0072061	2	0.018
negative regulation of cell development	GO:0010721	169	0.018	Mouse
carbohydrate biosynthetic process	GO:0016051	74	0.018
cytoplasmic transport	GO:0016482	234	0.018
nuclear division	GO:0000280	158	0.018
compound eye development	GO:0048749	1	0.018
ameboidal type cell migration	GO:0001667	128	0.018	Mouse
muscle cell proliferation	GO:0033002	52	0.018	Mouse
positive regulation of neuroblast proliferation	GO:0002052	19	0.018
satellite cell activation involved in skeletal muscle regeneration	GO:0014901	3	0.018
regulation of striated muscle cell differentiation	GO:0051153	81	0.018
positive regulation of angiogenesis	GO:0045766	46	0.018	Mouse
rap protein signal transduction	GO:0032486	3	0.018
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.018
non canonical wnt signaling pathway	GO:0035567	33	0.018
protein import into nucleus	GO:0006606	95	0.017
response to radiation	GO:0009314	165	0.017
gliogenesis	GO:0042063	141	0.017
cell fate determination	GO:0001709	32	0.017
cochlea morphogenesis	GO:0090103	22	0.017
bone mineralization	GO:0030282	54	0.017
gonad development	GO:0008406	141	0.017
formation of primary germ layer	GO:0001704	77	0.017	Mouse
negative regulation of testosterone biosynthetic process	GO:2000225	1	0.017
regulation of metal ion transport	GO:0010959	106	0.017
regulation of mitotic cell cycle	GO:0007346	126	0.017
neuron migration	GO:0001764	122	0.017
positive regulation of hydrolase activity	GO:0051345	148	0.017
lipid biosynthetic process	GO:0008610	179	0.017
anatomical structure homeostasis	GO:0060249	145	0.017
reactive oxygen species biosynthetic process	GO:1903409	8	0.017
hematopoietic progenitor cell differentiation	GO:0002244	143	0.017
regulation of hepatocyte differentiation	GO:0070366	2	0.017
endocrine process	GO:0050886	39	0.017
mesoderm formation	GO:0001707	62	0.017	Mouse
action potential	GO:0001508	78	0.017
negative regulation of proteolysis	GO:0045861	74	0.017
hepaticobiliary system development	GO:0061008	67	0.017	Mouse
neural tube formation	GO:0001841	108	0.017	Mouse
regulation of endopeptidase activity	GO:0052548	89	0.017
cellular modified amino acid metabolic process	GO:0006575	63	0.017
cerebellar cortex development	GO:0021695	48	0.017
development of primary sexual characteristics	GO:0045137	143	0.017
regulation of removal of superoxide radicals	GO:2000121	4	0.017
monosaccharide biosynthetic process	GO:0046364	44	0.017
multi multicellular organism process	GO:0044706	109	0.016	Mouse
chorion development	GO:0060717	7	0.016
muscle hypertrophy	GO:0014896	24	0.016	Mouse
glial cell differentiation	GO:0010001	131	0.016
regulation of actin filament polymerization	GO:0030833	38	0.016
positive regulation of branching involved in lung morphogenesis	GO:0061047	4	0.016
lipid modification	GO:0030258	65	0.016
positive regulation of transforming growth factor beta2 production	GO:0032915	2	0.016
brown fat cell differentiation	GO:0050873	36	0.016
cellular response to acid chemical	GO:0071229	68	0.016
positive regulation of proteolysis	GO:0045862	85	0.016
glucose import	GO:0046323	32	0.016
regulation of carbohydrate metabolic process	GO:0006109	75	0.016
muscular septum morphogenesis	GO:0003150	4	0.016
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.016
negative regulation of canonical wnt signaling pathway	GO:0090090	51	0.016
positive regulation of lymphocyte activation	GO:0051251	140	0.016
regulation of lymphocyte activation	GO:0051249	240	0.016
nuclear transport	GO:0051169	139	0.016
regulation of synaptic plasticity	GO:0048167	87	0.016
positive regulation of map kinase activity	GO:0043406	84	0.016
renal tubule morphogenesis	GO:0061333	72	0.016
regulation of organelle organization	GO:0033043	289	0.016
negative regulation of androgen biosynthetic process	GO:2000180	1	0.015
organonitrogen compound biosynthetic process	GO:1901566	192	0.015
cell cell junction organization	GO:0045216	72	0.015
regulation of cellular component size	GO:0032535	121	0.015
stress activated mapk cascade	GO:0051403	80	0.015
regulation of jnk cascade	GO:0046328	62	0.015
amine metabolic process	GO:0009308	45	0.015
regulation of bone mineralization	GO:0030500	31	0.015
negative regulation of cellular component organization	GO:0051129	194	0.015
b cell activation	GO:0042113	161	0.015
nucleoside phosphate metabolic process	GO:0006753	338	0.015
regulation of peptidase activity	GO:0052547	96	0.015
cellular response to steroid hormone stimulus	GO:0071383	33	0.015
wnt signaling pathway calcium modulating pathway	GO:0007223	2	0.015
sulfur compound metabolic process	GO:0006790	100	0.015
negative regulation of endopeptidase activity	GO:0010951	44	0.015
membrane depolarization	GO:0051899	64	0.015
lipid catabolic process	GO:0016042	69	0.015
hypophysis morphogenesis	GO:0048850	3	0.015
negative regulation of wnt signaling pathway	GO:0030178	73	0.015
carbohydrate derivative biosynthetic process	GO:1901137	183	0.015
regulation of protein processing	GO:0070613	96	0.015

Gdf10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
musculoskeletal system disease	DOID:17	0.087
disease of anatomical entity	DOID:7	0.087
nervous system disease	DOID:863	0.021

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