Mus musculus

0 known processes

Lta4h

leukotriene A4 hydrolase

Lta4h biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleobase containing small molecule metabolic processGO:00550863520.078
cellular amine metabolic processGO:0044106440.078
aromatic compound catabolic processGO:00194392860.060
amine metabolic processGO:0009308450.059
cellular nitrogen compound catabolic processGO:00442702800.059
dna metabolic processGO:00062593030.055
cellular amino acid metabolic processGO:00065201030.054
cellular ketone metabolic processGO:0042180840.051
heterocycle catabolic processGO:00467002800.051
regulation of cellular amine metabolic processGO:0033238200.050
organic cyclic compound catabolic processGO:19013612950.048
purine nucleotide metabolic processGO:00061633020.046
purine containing compound metabolic processGO:00725213110.046
nucleoside phosphate metabolic processGO:00067533380.044
organonitrogen compound catabolic processGO:19015652640.041
regulation of cellular catabolic processGO:00313292420.041
purine ribonucleotide metabolic processGO:00091502900.040
nucleotide metabolic processGO:00091173320.040
carbohydrate derivative catabolic processGO:19011362310.039
ribose phosphate metabolic processGO:00196932910.038
peptidyl amino acid modificationGO:00181933360.038
ribonucleotide metabolic processGO:00092592910.038
regulation of cellular amino acid metabolic processGO:000652150.038
purine ribonucleoside catabolic processGO:00461302050.037
purine ribonucleotide catabolic processGO:00091542080.036
cell type specific apoptotic processGO:00972852680.036
ras protein signal transductionGO:0007265770.035
glycosyl compound metabolic processGO:19016572460.034
purine nucleoside catabolic processGO:00061522050.033
t cell activationGO:00421102890.033
purine nucleoside triphosphate catabolic processGO:00091462030.032
purine nucleoside metabolic processGO:00422782410.032
cellular lipid metabolic processGO:00442553230.032
Yeast Rat
regulation of cell activationGO:00508652890.032
regulation of organelle organizationGO:00330432890.031
organonitrogen compound biosynthetic processGO:19015661920.031
purine ribonucleoside metabolic processGO:00461282410.031
regulation of hydrolase activityGO:00513362460.031
nucleoside triphosphate metabolic processGO:00091412300.031
regulation of cellular ketone metabolic processGO:0010565660.031
purine nucleoside triphosphate metabolic processGO:00091442260.031
nucleoside metabolic processGO:00091162460.030
nucleoside phosphate catabolic processGO:19012922220.030
ribonucleoside metabolic processGO:00091192450.030
protein modification by small protein conjugation or removalGO:00706472070.029
membrane organizationGO:00610242450.028
purine containing compound catabolic processGO:00725232130.028
oxidation reduction processGO:00551143420.028
nucleotide catabolic processGO:00091662170.028
cytokine productionGO:00018163190.028
nucleoside triphosphate catabolic processGO:00091432050.028
immune effector processGO:00022523210.028
purine ribonucleoside triphosphate metabolic processGO:00092052200.028
lymphocyte differentiationGO:00300982420.028
organophosphate catabolic processGO:00464342320.028
macromolecule catabolic processGO:00090572810.028
Yeast
ribonucleoside triphosphate catabolic processGO:00092031990.027
carbohydrate metabolic processGO:00059752300.027
cellular response to dna damage stimulusGO:00069742070.027
transmembrane transportGO:00550854120.027
nucleoside catabolic processGO:00091642060.027
regulation of lymphocyte activationGO:00512492400.027
glycosyl compound catabolic processGO:19016582060.027
microtubule based processGO:00070172360.026
purine ribonucleoside triphosphate catabolic processGO:00092071990.026
leukocyte proliferationGO:00706611720.026
regulation of gtp catabolic processGO:00331241130.026
cell adhesionGO:00071553290.026
negative regulation of phosphorus metabolic processGO:00105631840.026
ribonucleotide catabolic processGO:00092612080.026
positive regulation of protein phosphorylationGO:00019342420.026
protein modification by small protein conjugationGO:00324461870.025
cellular macromolecule catabolic processGO:00442652060.025
chemotaxisGO:00069352470.025
cation transportGO:00068123990.025
small gtpase mediated signal transductionGO:0007264970.025
purine nucleotide catabolic processGO:00061952110.025
lymphocyte proliferationGO:00466511640.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
cellular homeostasisGO:00197252400.025
regulation of cell cycleGO:00517262810.024
positive regulation of apoptotic processGO:00430652170.024
negative regulation of protein metabolic processGO:00512482820.024
ion transmembrane transportGO:00342203610.024
chromatin organizationGO:00063252060.024
cellular response to cytokine stimulusGO:00713451890.024
positive regulation of cell deathGO:00109422240.024
leukocyte differentiationGO:00025213420.023
regulation of protein localizationGO:00328802310.023
regulation of cytokine productionGO:00018172660.023
g protein coupled receptor signaling pathwayGO:00071862430.023
ribonucleoside catabolic processGO:00424542060.023
guanosine containing compound catabolic processGO:19010691440.022
negative regulation of phosphorylationGO:00423261660.022
regulation of cell migrationGO:00303342190.022
positive regulation of hydrolase activityGO:00513451480.022
carbohydrate derivative biosynthetic processGO:19011371830.022
negative regulation of cellular component organizationGO:00511291940.022
negative regulation of cell proliferationGO:00082852960.022
synaptic transmissionGO:00072683290.022
negative regulation of intracellular signal transductionGO:19025321670.022
regulation of t cell activationGO:00508631700.021
regulation of transferase activityGO:00513382630.021
ribonucleoside triphosphate metabolic processGO:00091992200.021
dna repairGO:00062811070.021
regulation of cell motilityGO:20001452360.021
positive regulation of protein modification processGO:00314012990.021
mitotic cell cycleGO:00002781950.021
regulation of kinase activityGO:00435492490.021
positive regulation of cellular amine metabolic processGO:003324050.021
regulation of nucleotide catabolic processGO:00308111220.021
protein maturationGO:00516041760.021
cellular chemical homeostasisGO:00550822150.021
negative regulation of cellular amine metabolic processGO:003323910.021
sensory perceptionGO:00076002450.021
apoptotic signaling pathwayGO:00971903060.021
anatomical structure homeostasisGO:00602491450.020
protein catabolic processGO:00301632210.020
Yeast
guanosine containing compound metabolic processGO:19010681440.020
response to acid chemicalGO:00011011110.020
gtp metabolic processGO:00460391440.020
response to radiationGO:00093141650.020
cytoplasmic transportGO:00164822340.020
hematopoietic progenitor cell differentiationGO:00022441430.020
positive regulation of programmed cell deathGO:00430682180.020
methylationGO:00322591340.020
regulation of protein kinase activityGO:00458592320.020
organelle assemblyGO:00709251770.019
organophosphate biosynthetic processGO:00904071220.019
chromatin modificationGO:00165681870.019
negative regulation of immune system processGO:00026832090.019
endomembrane system organizationGO:00102561470.019
axonogenesisGO:00074092740.019
covalent chromatin modificationGO:00165691630.019
retrograde transport endosome to golgiGO:004214720.019
homeostasis of number of cellsGO:00488722100.019
negative regulation of cellular protein metabolic processGO:00322692470.019
negative regulation of phosphate metabolic processGO:00459361840.019
response to light stimulusGO:00094161350.018
dna recombinationGO:0006310920.018
cation transmembrane transportGO:00986552660.018
mapk cascadeGO:00001652810.018
regulation of nucleoside metabolic processGO:00091181300.018
regulation of proteolysisGO:00301621640.018
positive regulation of cell activationGO:00508671580.018
gland developmentGO:00487323300.018
regulation of nucleotide metabolic processGO:00061401690.018
regulation of leukocyte proliferationGO:00706631210.018
positive regulation of lymphocyte activationGO:00512511400.018
regulation of mapk cascadeGO:00434082480.018
t cell proliferationGO:00420981200.018
mitotic cell cycle processGO:19030471590.018
divalent metal ion transportGO:00708381720.018
myeloid cell differentiationGO:00300992330.017
meiotic cell cycleGO:00513211220.017
regulation of defense responseGO:00313472330.017
divalent inorganic cation transportGO:00725111780.017
muscle cell differentiationGO:00426922610.017
regulation of purine nucleotide catabolic processGO:00331211220.017
nuclear divisionGO:00002801580.017
wnt signaling pathwayGO:00160551880.017
inflammatory responseGO:00069542440.017
Zebrafish
protein localization to organelleGO:00333651850.017
intracellular protein transportGO:00068862040.017
regulation of neuron differentiationGO:00456642810.017
actin cytoskeleton organizationGO:00300362200.017
b cell activationGO:00421131610.017
regulation of cell projection organizationGO:00313442060.017
regulation of inflammatory responseGO:00507271470.017
cation homeostasisGO:00550802120.017
regulation of membrane potentialGO:00423911920.016
myosin filament organizationGO:003103330.016
cellular response to lipidGO:00713961450.016
rho protein signal transductionGO:0007266320.016
neuron deathGO:00709971540.016
spermatogenesisGO:00072832840.016
positive regulation of nucleotide metabolic processGO:00459811140.016
regulation of body fluid levelsGO:00508781620.016
cellular component assembly involved in morphogenesisGO:00109271390.016
sequestering of calcium ionGO:0051208180.016
regulation of secretionGO:00510462740.016
protein targetingGO:00066051430.016
histone modificationGO:00165701590.016
nitrogen compound transportGO:00717052710.016
forebrain developmentGO:00309003020.016
myeloid leukocyte differentiationGO:00025731190.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
sulfur compound metabolic processGO:00067901000.016
response to growth factorGO:00708481980.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.015
carbohydrate homeostasisGO:00335001280.015
regulation of cell adhesionGO:00301551540.015
multicellular organismal homeostasisGO:00488711640.015
positive regulation of secretionGO:00510471300.015
protein ubiquitinationGO:00165671710.015
inorganic ion transmembrane transportGO:00986602340.015
response to molecule of bacterial originGO:00022371430.015
skeletal system developmentGO:00015013560.015
positive regulation of cell developmentGO:00107202370.015
regulation of cellular response to stressGO:00801351590.015
camera type eye developmentGO:00430102660.015
regulation of response to woundingGO:19030341890.015
glycoprotein metabolic processGO:00091001160.015
regulation of secretion by cellGO:19035302490.015
gtp catabolic processGO:00061841430.015
cell activation involved in immune responseGO:00022631260.015
metal ion homeostasisGO:00550651890.015
regulation of wnt signaling pathwayGO:00301111230.015
regulation of purine nucleotide metabolic processGO:19005421690.014
glucose homeostasisGO:00425931280.014
intrinsic apoptotic signaling pathwayGO:00971931320.014
epithelial tube morphogenesisGO:00605623030.014
mitochondrion organizationGO:00070051340.014
negative regulation of molecular functionGO:00440922580.014
negative regulation of protein modification processGO:00314001630.014
regulation of apoptotic signaling pathwayGO:20012331970.014
positive regulation of interleukin 8 productionGO:003275720.014
cellular ion homeostasisGO:00068731650.014
positive regulation of gtpase activityGO:0043547850.014
positive regulation of transferase activityGO:00513471670.014
asymmetric stem cell divisionGO:009872230.014
cellular protein complex assemblyGO:00436231160.014
cellular response to growth factor stimulusGO:00713631970.014
regulation of lymphocyte proliferationGO:00506701170.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
cognitionGO:00508901490.014
monocarboxylic acid metabolic processGO:00327871910.014
Rat
negative regulation of cell developmentGO:00107211690.014
digestive system developmentGO:00551232000.014
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.014
t cell differentiationGO:00302171740.014
lipid biosynthetic processGO:00086101790.014
b cell differentiationGO:0030183780.014
inorganic cation transmembrane transportGO:00986622070.014
maintenance of locationGO:0051235890.014
regulation of b cell activationGO:0050864810.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.014
cellular carbohydrate metabolic processGO:00442621190.014
response to extracellular stimulusGO:00099911270.014
striated muscle tissue developmentGO:00147062930.014
protein processingGO:00164851630.014
mrna metabolic processGO:0016071840.013
locomotory behaviorGO:00076261950.013
developmental maturationGO:00217001930.013
blood circulationGO:00080151950.013
regulation of ion transportGO:00432692150.013
cell divisionGO:00513011200.013
regulation of cytoskeleton organizationGO:00514931220.013
protein secretionGO:00093061110.013
regulation of leukocyte differentiationGO:19021051590.013
meiotic nuclear divisionGO:00071261150.013
learning or memoryGO:00076111480.013
regulation of protein transportGO:00512231630.013
regulation of t cell proliferationGO:0042129920.013
digestive tract developmentGO:00485651900.013
macromolecule methylationGO:00434141200.013
innate immune responseGO:00450871570.013
monosaccharide metabolic processGO:00059961060.013
positive regulation of purine nucleotide metabolic processGO:19005441140.013
negative regulation of cell cycleGO:00457861230.013
organelle localizationGO:00516401790.013
respiratory system developmentGO:00605411900.013
Rat
myosin filament assemblyGO:003103420.013
response to organonitrogen compoundGO:00102432460.013
Rat
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
regulation of ras protein signal transductionGO:00465781140.013
calcium ion transportGO:00068161590.013
morphogenesis of a branching epitheliumGO:00611381930.013
regulation of homeostatic processGO:00328441820.012
posttranscriptional regulation of gene expressionGO:00106081550.012
protein localization to nucleusGO:00345041210.012
regulation of interleukin 8 productionGO:003267730.012
response to oxidative stressGO:00069791230.012
negative regulation of protein phosphorylationGO:00019331260.012
anion transportGO:00068201770.012
regulation of establishment of protein localizationGO:00702011810.012
sensory system developmentGO:004888030.012
striated muscle myosin thick filament assemblyGO:007168810.012
muscle contractionGO:00069361010.012
positive regulation of cytokine productionGO:00018191740.012
positive regulation of nucleoside metabolic processGO:0045979910.012
gonad developmentGO:00084061410.012
muscle tissue developmentGO:00605373080.012
sequestering of metal ionGO:0051238190.012
positive regulation of t cell activationGO:00508701010.012
compound eye developmentGO:004874910.012
action potentialGO:0001508780.012
regulation of cellular component biogenesisGO:00440871810.012
neuron apoptotic processGO:00514021420.012
hexose metabolic processGO:0019318980.012
peptidyl tyrosine modificationGO:00182121450.012
cellular response to extracellular stimulusGO:0031668810.012
regulation of vesicle mediated transportGO:00606271390.012
organic hydroxy compound metabolic processGO:19016152030.012
reactive oxygen species metabolic processGO:0072593840.012
defense response to other organismGO:00985421970.012
asymmetric neuroblast divisionGO:005505910.012
stem cell developmentGO:00488642190.012
regulation of multi organism processGO:00439001110.012
peptidyl tyrosine phosphorylationGO:00181081430.012
regulation of neuron projection developmentGO:00109751690.012
regulation of mitotic cell cycleGO:00073461260.011
meiotic cell cycle processGO:1903046770.011
calcium ion homeostasisGO:00550741270.011
positive regulation of defense responseGO:00313491240.011
male gamete generationGO:00482322850.011
nucleic acid phosphodiester bond hydrolysisGO:0090305490.011
interleukin 8 productionGO:003263740.011
negative regulation of lymphocyte activationGO:0051250910.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
tube formationGO:00351481400.011
peptide transportGO:00158331330.011
negative regulation of cell activationGO:00508661110.011
multicellular organismal signalingGO:0035637910.011
positive regulation of immune effector processGO:00026991070.011
germ cell developmentGO:00072811850.011
rna interferenceGO:001624620.011
regulation of anatomical structure sizeGO:00900661780.011
cofactor metabolic processGO:0051186800.011
multi multicellular organism processGO:00447061090.011
positive regulation of cellular catabolic processGO:00313311480.011
sphingolipid metabolic processGO:0006665450.011
pharynx developmentGO:006046510.011
epithelial cell proliferationGO:00506731740.011
reactive nitrogen species metabolic processGO:200105700.011
cellular metal ion homeostasisGO:00068751510.011
endocytosisGO:00068971680.011
leukocyte migrationGO:00509001240.011
double strand break repairGO:0006302480.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
morphogenesis of a branching structureGO:00017632030.011
alpha beta t cell differentiationGO:0046632690.011
ossificationGO:00015032160.011
fatty acid metabolic processGO:00066311210.011
Rat
regulation of transmembrane transportGO:00347621280.011
cellular response to molecule of bacterial originGO:0071219830.011
establishment of organelle localizationGO:00516561220.011
dendrite developmentGO:00163581150.011
fat cell differentiationGO:00454441600.011
regulation of actin nucleationGO:005112540.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
positive regulation of protein transportGO:0051222930.011
regulation of peptidase activityGO:0052547960.011
regulation of interleukin 1 alpha productionGO:003265040.010
neural precursor cell proliferationGO:00613511210.010
heart morphogenesisGO:00030071780.010
negative regulation of nik nf kappab signalingGO:190122320.010
cellular response to hormone stimulusGO:00328701500.010
positive regulation of secretion by cellGO:19035321140.010
alpha beta t cell activationGO:0046631910.010
tissue homeostasisGO:00018941150.010
ear developmentGO:00435832000.010
positive regulation of gtp catabolic processGO:0033126850.010
regulation of protein maturationGO:1903317960.010
regulation of intracellular transportGO:00323861590.010
divalent inorganic cation homeostasisGO:00725071380.010
negative regulation of nervous system developmentGO:00519611560.010
glucose metabolic processGO:0006006920.010
regulation of endopeptidase activityGO:0052548890.010
membrane depolarizationGO:0051899640.010
lymphocyte mediated immunityGO:00024491390.010
cellular protein catabolic processGO:00442571550.010
alpha amino acid metabolic processGO:1901605590.010
negative regulation of wnt signaling pathwayGO:0030178730.010
nuclear transportGO:00511691390.010
circulatory system processGO:00030131970.010
cellular response to biotic stimulusGO:0071216920.010
regulation of neuron apoptotic processGO:00435231220.010
regulation of reactive oxygen species metabolic processGO:2000377400.010
skeletal muscle organ developmentGO:00605381630.010
response to transforming growth factor betaGO:0071559880.010
microtubule cytoskeleton organizationGO:00002261570.010
organelle fissionGO:00482851700.010

Lta4h disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.019
nervous system diseaseDOID:86300.018
disease of anatomical entityDOID:700.018
inherited metabolic disorderDOID:65500.016
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.015
immune system diseaseDOID:291400.014
sensory system diseaseDOID:005015500.012
central nervous system diseaseDOID:33100.011
connective tissue diseaseDOID:6500.010
musculoskeletal system diseaseDOID:1700.010
cardiovascular system diseaseDOID:128700.010