Mus musculus

36 known processes

Clcn3

chloride channel 3

(Aliases: Clc3)

Clcn3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation homeostasisGO:00550802120.153
Yeast
cellular protein catabolic processGO:00442571550.138
nucleotide metabolic processGO:00091173320.124
purine ribonucleoside metabolic processGO:00461282410.119
cellular macromolecule catabolic processGO:00442652060.119
cellular metal ion homeostasisGO:00068751510.104
Yeast
protein ubiquitinationGO:00165671710.104
purine nucleoside metabolic processGO:00422782410.101
ribonucleotide metabolic processGO:00092592910.100
cellular ion homeostasisGO:00068731650.100
Yeast
nucleoside metabolic processGO:00091162460.099
protein modification by small protein conjugation or removalGO:00706472070.098
purine nucleotide metabolic processGO:00061633020.097
cellular homeostasisGO:00197252400.090
Yeast
regulation of cellular catabolic processGO:00313292420.088
cellular chemical homeostasisGO:00550822150.086
Yeast
protein modification by small protein conjugationGO:00324461870.085
positive regulation of cellular catabolic processGO:00313311480.077
nucleoside phosphate metabolic processGO:00067533380.075
macromolecule catabolic processGO:00090572810.075
proteolysis involved in cellular protein catabolic processGO:00516031470.073
protein catabolic processGO:00301632210.070
nucleoside triphosphate metabolic processGO:00091412300.068
cation transportGO:00068123990.066
purine nucleoside triphosphate catabolic processGO:00091462030.066
nucleobase containing small molecule metabolic processGO:00550863520.061
synaptic transmissionGO:00072683290.060
ribonucleoside metabolic processGO:00091192450.055
divalent inorganic cation homeostasisGO:00725071380.054
purine ribonucleoside catabolic processGO:00461302050.050
purine ribonucleotide metabolic processGO:00091502900.050
ubiquitin dependent protein catabolic processGO:00065111290.049
regulation of membrane potentialGO:00423911920.049
ribose phosphate metabolic processGO:00196932910.048
purine containing compound catabolic processGO:00725232130.048
apoptotic signaling pathwayGO:00971903060.048
mitochondrion organizationGO:00070051340.048
purine nucleoside catabolic processGO:00061522050.048
heterocycle catabolic processGO:00467002800.045
endomembrane system organizationGO:00102561470.045
nucleotide catabolic processGO:00091662170.044
cofactor biosynthetic processGO:0051188410.044
modification dependent protein catabolic processGO:00199411330.042
small gtpase mediated signal transductionGO:0007264970.042
ribonucleoside triphosphate metabolic processGO:00091992200.042
cofactor metabolic processGO:0051186800.042
cellular lipid metabolic processGO:00442553230.041
cellular transition metal ion homeostasisGO:0046916320.041
Yeast
regulation of nucleotide metabolic processGO:00061401690.040
purine containing compound metabolic processGO:00725213110.040
ion transmembrane transportGO:00342203610.040
Yeast Rat
gtp metabolic processGO:00460391440.040
cellular response to growth factor stimulusGO:00713631970.040
glycosyl compound metabolic processGO:19016572460.040
negative regulation of phosphate metabolic processGO:00459361840.039
organonitrogen compound catabolic processGO:19015652640.039
ras protein signal transductionGO:0007265770.039
oxidation reduction processGO:00551143420.038
regulation of homeostatic processGO:00328441820.037
positive regulation of proteolysisGO:0045862850.037
transmembrane transportGO:00550854120.037
Yeast Rat
organonitrogen compound biosynthetic processGO:19015661920.037
negative regulation of phosphorus metabolic processGO:00105631840.035
cellular divalent inorganic cation homeostasisGO:00725031270.034
ribonucleotide catabolic processGO:00092612080.034
gtp catabolic processGO:00061841430.034
sequestering of metal ionGO:0051238190.034
metal ion homeostasisGO:00550651890.034
Yeast
calcium ion homeostasisGO:00550741270.034
divalent inorganic cation transportGO:00725111780.034
lipid localizationGO:00108761260.033
nucleoside phosphate catabolic processGO:19012922220.033
membrane organizationGO:00610242450.033
divalent metal ion transportGO:00708381720.032
protein modification by small protein removalGO:0070646210.032
organic cyclic compound catabolic processGO:19013612950.032
response to growth factorGO:00708481980.032
protein polyubiquitinationGO:0000209330.031
compound eye developmentGO:004874910.031
translationGO:0006412930.031
calcium ion transportGO:00068161590.031
purine ribonucleotide catabolic processGO:00091542080.031
multicellular organismal homeostasisGO:00488711640.031
maintenance of locationGO:0051235890.031
cellular amino acid metabolic processGO:00065201030.031
mapk cascadeGO:00001652810.030
positive regulation of growthGO:00459271040.030
regulation of purine nucleotide catabolic processGO:00331211220.029
regulation of proteolysisGO:00301621640.029
response to oxidative stressGO:00069791230.029
regulation of ion transportGO:00432692150.029
Yeast Rat
cellular carbohydrate metabolic processGO:00442621190.028
modification dependent macromolecule catabolic processGO:00436321330.028
response to transforming growth factor betaGO:0071559880.028
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.028
carbohydrate metabolic processGO:00059752300.028
sequestering of calcium ionGO:0051208180.028
regulation of hydrolase activityGO:00513362460.028
guanosine containing compound catabolic processGO:19010691440.028
regulation of transferase activityGO:00513382630.028
organophosphate catabolic processGO:00464342320.028
immune effector processGO:00022523210.027
purine ribonucleoside triphosphate catabolic processGO:00092071990.027
atp catabolic processGO:0006200550.027
purine nucleoside triphosphate metabolic processGO:00091442260.027
purine ribonucleoside triphosphate metabolic processGO:00092052200.027
organelle localizationGO:00516401790.027
positive regulation of cellular amine metabolic processGO:003324050.027
cellular calcium ion homeostasisGO:00068741190.027
response to endoplasmic reticulum stressGO:0034976530.026
nucleoside catabolic processGO:00091642060.026
spermatogenesisGO:00072832840.026
regulation of ion transmembrane transportGO:00347651190.026
Yeast Rat
rho protein signal transductionGO:0007266320.026
leukocyte differentiationGO:00025213420.025
regulation of nucleotide catabolic processGO:00308111220.025
forebrain developmentGO:00309003020.025
regulation of cell projection organizationGO:00313442060.025
cation transmembrane transportGO:00986552660.024
regulation of cell cycleGO:00517262810.024
inorganic ion transmembrane transportGO:00986602340.024
Yeast Rat
inorganic cation transmembrane transportGO:00986622070.023
homeostasis of number of cellsGO:00488722100.023
ribonucleoside triphosphate catabolic processGO:00092031990.023
nitrogen compound transportGO:00717052710.023
regulation of cellular amine metabolic processGO:0033238200.023
cellular nitrogen compound catabolic processGO:00442702800.023
regulation of organelle organizationGO:00330432890.023
multicellular organism growthGO:00352641610.023
negative regulation of apoptotic signaling pathwayGO:20012341040.023
cytoplasmic transportGO:00164822340.023
inter male aggressive behaviorGO:000212130.023
organophosphate biosynthetic processGO:00904071220.022
regulation of cellular protein catabolic processGO:1903362610.022
cellular amine metabolic processGO:0044106440.022
epithelium migrationGO:0090132630.022
meiosis iGO:0007127600.022
microtubule cytoskeleton organizationGO:00002261570.022
cellular ketone metabolic processGO:0042180840.022
lipid biosynthetic processGO:00086101790.021
glycosyl compound catabolic processGO:19016582060.021
cellular response to oxidative stressGO:0034599760.021
plasma membrane organizationGO:0007009900.021
regulation of purine nucleotide metabolic processGO:19005421690.021
gonad developmentGO:00084061410.021
organelle fissionGO:00482851700.021
proteasomal protein catabolic processGO:0010498980.021
guanosine containing compound metabolic processGO:19010681440.021
gland developmentGO:00487323300.020
carbohydrate derivative catabolic processGO:19011362310.020
regulation of ion homeostasisGO:2000021640.020
regulation of metal ion transportGO:00109591060.020
negative regulation of molecular functionGO:00440922580.020
positive regulation of purine nucleotide metabolic processGO:19005441140.020
myeloid cell differentiationGO:00300992330.020
monocarboxylic acid metabolic processGO:00327871910.020
telencephalon developmentGO:00215371860.020
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.019
regulation of lipid metabolic processGO:00192161180.019
chromatin organizationGO:00063252060.019
regulation of synaptic plasticityGO:0048167870.019
iron ion homeostasisGO:0055072360.019
Yeast
regulation of nucleoside metabolic processGO:00091181300.019
generation of precursor metabolites and energyGO:00060911030.019
regulation of synaptic growth at neuromuscular junctionGO:000858240.019
carbohydrate catabolic processGO:0016052320.019
methylationGO:00322591340.019
cell type specific apoptotic processGO:00972852680.019
cellular response to transforming growth factor beta stimulusGO:0071560880.019
response to organonitrogen compoundGO:00102432460.019
sensory organ morphogenesisGO:00905962420.019
circadian regulation of gene expressionGO:0032922480.019
cytokine productionGO:00018163190.019
regulation of anatomical structure sizeGO:00900661780.019
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.018
carbohydrate homeostasisGO:00335001280.018
intracellular protein transportGO:00068862040.018
regulation of cellular ketone metabolic processGO:0010565660.018
aromatic compound catabolic processGO:00194392860.018
regulation of protein catabolic processGO:00421761080.018
synapsisGO:0007129340.018
epithelial tube morphogenesisGO:00605623030.018
negative regulation of phosphorylationGO:00423261660.018
positive regulation of cellular amino acid metabolic processGO:004576430.018
cellular response to arsenic containing substanceGO:007124340.018
hypotonic responseGO:000697130.018
fat cell differentiationGO:00454441600.018
synapse organizationGO:00508081250.018
regulation of cell migrationGO:00303342190.018
regulation of kinase activityGO:00435492490.018
circadian rhythmGO:00076231140.018
positive regulation of protein modification processGO:00314012990.018
nucleoside triphosphate catabolic processGO:00091432050.017
regulation of mrna polyadenylationGO:190036310.017
regulation of neuron projection developmentGO:00109751690.017
transforming growth factor beta receptor signaling pathwayGO:0007179710.017
neuronal action potentialGO:0019228540.017
morphogenesis of embryonic epitheliumGO:00163311590.017
cognitionGO:00508901490.017
negative regulation of mapk cascadeGO:0043409650.017
negative regulation of protein metabolic processGO:00512482820.017
regulation of neuron differentiationGO:00456642810.017
posttranscriptional regulation of gene expressionGO:00106081550.017
amine metabolic processGO:0009308450.017
limbic system developmentGO:0021761720.017
intrinsic apoptotic signaling pathwayGO:00971931320.017
protein deubiquitinationGO:0016579190.017
transition metal ion homeostasisGO:0055076540.017
Yeast
regulation of carbohydrate metabolic processGO:0006109750.017
protein localization to membraneGO:00726571080.017
regulation of cellular component sizeGO:00325351210.017
neuron deathGO:00709971540.017
regulation of ras protein signal transductionGO:00465781140.017
positive regulation of homeostatic processGO:0032846640.017
glucose homeostasisGO:00425931280.017
positive regulation of hydrolase activityGO:00513451480.017
regulation of cellular component biogenesisGO:00440871810.016
negative regulation of immune system processGO:00026832090.016
ribonucleoside monophosphate metabolic processGO:0009161800.016
protein localization to plasma membraneGO:0072659570.016
leukocyte activation involved in immune responseGO:00023661260.016
negative regulation of cellular protein metabolic processGO:00322692470.016
development of primary sexual characteristicsGO:00451371430.016
dendrite developmentGO:00163581150.016
defecationGO:003042110.016
peptidyl amino acid modificationGO:00181933360.016
glycoprotein metabolic processGO:00091001160.015
negative regulation of intracellular signal transductionGO:19025321670.015
myeloid cell homeostasisGO:00022621140.015
negative regulation of cellular response to growth factor stimulusGO:0090288460.015
cell adhesionGO:00071553290.015
neural precursor cell proliferationGO:00613511210.015
purine nucleotide catabolic processGO:00061952110.015
negative regulation of protein phosphorylationGO:00019331260.015
regulation of vesicle mediated transportGO:00606271390.015
transition metal ion transportGO:0000041380.015
cell activation involved in immune responseGO:00022631260.015
germ cell developmentGO:00072811850.015
response to epidermal growth factorGO:007084940.015
angiogenesisGO:00015252010.015
leukocyte mediated immunityGO:00024431740.015
regulation of cytoplasmic translationGO:200076540.015
fertilizationGO:00095661270.015
response to acid chemicalGO:00011011110.015
macromolecule methylationGO:00434141200.015
chromosome organization involved in meiosisGO:0070192390.015
response to nutrient levelsGO:00316671090.015
hippocampus developmentGO:0021766520.015
cytoplasmic translational elongationGO:000218210.015
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.015
amide transportGO:00428861380.014
male gamete generationGO:00482322850.014
muscle cell differentiationGO:00426922610.014
sensory perceptionGO:00076002450.014
protein processingGO:00164851630.014
regulation of cellular carbohydrate metabolic processGO:0010675750.014
regulation of mitochondrial fissionGO:009014030.014
g protein coupled receptor signaling pathwayGO:00071862430.014
exocytosisGO:00068871210.014
regulation of translationGO:0006417710.014
positive regulation of phospholipase activityGO:001051830.014
microtubule based processGO:00070172360.014
regulation of transmembrane transportGO:00347621280.014
Yeast Rat
early endosome to late endosome transportGO:004502220.014
meiotic cell cycleGO:00513211220.014
negative regulation of proteolysisGO:0045861740.014
protein palmitoylationGO:0018345140.014
camera type eye developmentGO:00430102660.014
organelle assemblyGO:00709251770.014
regulation of gtp catabolic processGO:00331241130.014
epithelial cell migrationGO:0010631630.014
male meiosisGO:0007140370.014
positive regulation of organelle organizationGO:00106381280.014
i kappab kinase nf kappab signalingGO:0007249850.014
innate immune responseGO:00450871570.013
regulation of apoptotic signaling pathwayGO:20012331970.013
rhythmic processGO:00485111740.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
glycoprotein biosynthetic processGO:0009101890.013
wnt signaling pathwayGO:00160551880.013
regulation of intracellular transportGO:00323861590.013
negative regulation of cell developmentGO:00107211690.013
cytokinetic processGO:003250620.013
tissue homeostasisGO:00018941150.013
cytosolic calcium ion homeostasisGO:0051480700.013
asymmetric stem cell divisionGO:009872230.013
respiratory system developmentGO:00605411900.013
positive regulation of cellular protein catabolic processGO:1903364340.013
histone modificationGO:00165701590.013
response to osmotic stressGO:0006970210.013
cellular response to epidermal growth factor stimulusGO:007136440.013
regulation of protein kinase activityGO:00458592320.013
protein maturationGO:00516041760.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
axonogenesisGO:00074092740.013
organic acid transportGO:00158491010.013
positive regulation of protein kinase activityGO:00458601440.013
alpha amino acid metabolic processGO:1901605590.013
striated muscle tissue developmentGO:00147062930.013
dephosphorylationGO:00163111290.013
energy derivation by oxidation of organic compoundsGO:0015980770.013
regulation of calcium ion transportGO:0051924690.013
positive regulation of protein catabolic processGO:0045732600.012
regulation of cellular response to growth factor stimulusGO:0090287820.012
establishment of blood nerve barrierGO:000806530.012
nucleoside monophosphate metabolic processGO:0009123850.012
actin filament organizationGO:00070151130.012
response to extracellular stimulusGO:00099911270.012
transmission of nerve impulseGO:0019226760.012
response to inorganic substanceGO:0010035960.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
insulin metabolic processGO:190114230.012
tissue migrationGO:0090130680.012
negative regulation of neuron differentiationGO:00456651010.012
regulation of secretionGO:00510462740.012
synaptonemal complex assemblyGO:0007130130.012
male meiosis iGO:0007141160.012
anion transportGO:00068201770.012
Yeast Rat
learning or memoryGO:00076111480.012
positive regulation of programmed cell deathGO:00430682180.012
phospholipid metabolic processGO:0006644870.012
negative regulation of purine nucleotide catabolic processGO:003312290.012
cellular response to peptideGO:1901653920.012
coenzyme metabolic processGO:0006732520.012
cellular modified amino acid metabolic processGO:0006575630.012
cellular response to organonitrogen compoundGO:00714171450.012
positive regulation of nucleotide metabolic processGO:00459811140.012
regulation of rho protein signal transductionGO:0035023710.012
cell growthGO:00160491300.012
peptidyl serine modificationGO:0018209830.012
calcium mediated signalingGO:0019722460.012
lateral inhibitionGO:004633110.012
regulation of inflammatory responseGO:00507271470.012
potassium ion transportGO:0006813520.012
action potentialGO:0001508780.012
establishment of organelle localizationGO:00516561220.012
regulation of cellular response to stressGO:00801351590.012
response to radiationGO:00093141650.012
cellular glucose homeostasisGO:0001678520.011
regulation of protein localizationGO:00328802310.011
localization within membraneGO:005166840.011
regionalizationGO:00030023370.011
peptide transportGO:00158331330.011
response to amino acidGO:0043200370.011
meiotic cell cycle processGO:1903046770.011
muscle system processGO:00030121410.011
negative regulation of protein modification processGO:00314001630.011
cell junction maintenanceGO:003433140.011
extracellular matrix organizationGO:00301981470.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.011
regulation of defense responseGO:00313472330.011
digestive tract developmentGO:00485651900.011
regulation of angiogenesisGO:0045765810.011
muscle contractionGO:00069361010.011
establishment or maintenance of cytoskeleton polarityGO:003095220.011
positive regulation of cell projection organizationGO:0031346950.011
regulation of rho gtpase activityGO:0032319580.011
stress activated mapk cascadeGO:0051403800.011
neuromuscular process controlling balanceGO:0050885590.011
response to molecule of bacterial originGO:00022371430.011
neuromuscular processGO:0050905990.011
protein targetingGO:00066051430.011
asymmetric neuroblast divisionGO:005505910.011
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.011
muscle tissue developmentGO:00605373080.011
small molecule biosynthetic processGO:00442831320.011
response to hypoxiaGO:0001666580.011
response to peptideGO:19016521360.011
epithelial cell developmentGO:00020641590.011
negative regulation of kinase activityGO:0033673810.011
regulation of cell sizeGO:0008361720.011
positive regulation of ion transportGO:0043270650.011
reactive oxygen species metabolic processGO:0072593840.011
glycerolipid metabolic processGO:00464861220.011
locomotory behaviorGO:00076261950.011
regulation of androgen receptor signaling pathwayGO:006076530.011
developmental growth involved in morphogenesisGO:00605601380.010
peptide metabolic processGO:0006518460.010
purine ribonucleoside monophosphate catabolic processGO:0009169570.010
cellular response to biotic stimulusGO:0071216920.010
actin cytoskeleton organizationGO:00300362200.010
positive regulation of purine nucleotide catabolic processGO:0033123880.010
negative regulation of cell proliferationGO:00082852960.010
skeletal muscle organ developmentGO:00605381630.010
neuron apoptotic processGO:00514021420.010
peptidyl serine phosphorylationGO:0018105740.010
myeloid leukocyte activationGO:0002274830.010
regulation of actin filament based processGO:0032970990.010
gliogenesisGO:00420631410.010
urogenital system developmentGO:00016552610.010
positive regulation of cell developmentGO:00107202370.010
respiratory tube developmentGO:00303231670.010
positive regulation of neuron projection developmentGO:0010976790.010
lipid homeostasisGO:0055088630.010
cellular iron ion homeostasisGO:0006879160.010
Yeast
ribonucleoside catabolic processGO:00424542060.010
response to oxygen levelsGO:0070482620.010
release of sequestered calcium ion into cytosolGO:0051209420.010
sulfur compound metabolic processGO:00067901000.010

Clcn3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.032
nervous system diseaseDOID:86300.032
disease of cellular proliferationDOID:1456600.023
central nervous system diseaseDOID:33100.019
neurodegenerative diseaseDOID:128900.019
cancerDOID:16200.019
organ system cancerDOID:005068600.019
musculoskeletal system diseaseDOID:1700.012
immune system diseaseDOID:291400.010