Mus musculus

14 known processes

Itgax

integrin alpha X

(Aliases: AI449405,N418,Cr4,Cd11c)

Itgax biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune response activating cell surface receptor signaling pathwayGO:0002429720.919
leukocyte chemotaxisGO:0030595690.909
Mouse
positive regulation of neutrophil chemotaxisGO:0090023120.906
regulation of monocyte chemotaxisGO:009002530.893
immune response activating signal transductionGO:00027571160.892
positive regulation of monocyte chemotaxisGO:009002620.870
mature dendritic cell differentiationGO:009702930.835
interleukin 12 secretionGO:007261030.834
regulation of cell migrationGO:00303342190.815
Mouse Fly
regulation of vesicle mediated transportGO:00606271390.813
Mouse
t cell differentiationGO:00302171740.792
leukocyte migrationGO:00509001240.780
Mouse
negative regulation of immune system processGO:00026832090.777
cell chemotaxisGO:0060326810.767
Mouse
calcium ion transport into cytosolGO:0060402480.757
positive regulation of eosinophil migrationGO:200041820.742
g protein coupled receptor signaling pathwayGO:00071862430.725
regulation of neutrophil chemotaxisGO:0090022140.716
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.711
positive regulation of cytokine secretionGO:0050715410.705
regulation of t cell activationGO:00508631700.699
Mouse
positive regulation of thymocyte migrationGO:200041220.694
negative regulation of macrophage apoptotic processGO:200011030.691
positive regulation of cell motilityGO:20001471160.656
Mouse
regulation of antigen processing and presentationGO:0002577100.652
alpha beta t cell activationGO:0046631910.649
positive regulation of chemotaxisGO:0050921380.637
regulation of leukocyte mediated immunityGO:00027031040.635
immune response regulating signaling pathwayGO:00027641250.632
positive regulation of granulocyte chemotaxisGO:0071624120.631
immune effector processGO:00022523210.626
regulation of cell activationGO:00508652890.621
Mouse
positive regulation of antigen processing and presentationGO:0002579100.620
regulation of innate immune responseGO:0045088910.616
leukocyte mediated immunityGO:00024431740.606
lymphocyte proliferationGO:00466511640.604
Mouse
regulation of cytokine productionGO:00018172660.604
antigen processing and presentationGO:0019882470.604
innate immune responseGO:00450871570.601
regulation of adaptive immune responseGO:0002819900.599
positive regulation of neutrophil migrationGO:1902624120.598
t cell activationGO:00421102890.591
Mouse
cytosolic calcium ion transportGO:0060401480.591
lymphocyte differentiationGO:00300982420.574
cellular calcium ion homeostasisGO:00068741190.573
regulation of cell motilityGO:20001452360.572
Mouse Fly
action potentialGO:0001508780.571
regulation of t cell costimulationGO:200052320.567
tumor necrosis factor productionGO:0032640500.566
leukocyte activation involved in immune responseGO:00023661260.557
activation of mapk activityGO:0000187590.554
positive regulation of dendritic cell dendrite assemblyGO:200054910.547
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.543
granulocyte chemotaxisGO:0071621390.542
Mouse
stimulatory c type lectin receptor signaling pathwayGO:000222320.541
myeloid cell activation involved in immune responseGO:0002275340.539
cd4 positive alpha beta t cell cytokine productionGO:003574340.529
cell activation involved in immune responseGO:00022631260.529
cytokine productionGO:00018163190.522
defense response to bacteriumGO:00427421190.517
defense response to other organismGO:00985421970.510
positive regulation of kinase activityGO:00336741550.509
sequestering of calcium ionGO:0051208180.507
dendritic cell chemotaxisGO:000240770.503
regulation of b cell chemotaxisGO:200053720.503
cellular response to cytokine stimulusGO:00713451890.501
negative regulation of homeostatic processGO:0032845710.496
granulocyte migrationGO:0097530430.496
Mouse
myeloid cell differentiationGO:00300992330.495
Mouse
endocytosisGO:00068971680.494
Mouse Fly
sequestering of metal ionGO:0051238190.488
regulation of thymocyte migrationGO:200041020.488
positive regulation of defense responseGO:00313491240.486
detection of external biotic stimulusGO:009858190.485
eosinophil migrationGO:007267730.484
adaptive immune responseGO:00022501550.475
regulation of eosinophil migrationGO:200041620.475
neutrophil chemotaxisGO:0030593360.473
Mouse
immune response regulating cell surface receptor signaling pathwayGO:0002768800.472
eosinophil activationGO:004330710.470
heterocycle catabolic processGO:00467002800.463
rho protein signal transductionGO:0007266320.455
Mouse
regulation of protein secretionGO:0050708820.453
positive regulation of leukocyte mediated immunityGO:0002705700.452
myeloid leukocyte differentiationGO:00025731190.451
Mouse
macrophage chemotaxisGO:0048246140.448
regulation of ion homeostasisGO:2000021640.437
regulation of lymphocyte activationGO:00512492400.431
Mouse
tumor necrosis factor superfamily cytokine productionGO:0071706510.427
myeloid leukocyte activationGO:0002274830.422
negative regulation of eosinophil degranulationGO:004331010.418
positive regulation of cell activationGO:00508671580.416
Mouse
positive regulation of leukocyte proliferationGO:0070665730.413
Mouse
positive regulation of cell migrationGO:00303351090.412
Mouse
thymocyte migrationGO:007267920.409
natural killer cell chemotaxisGO:003574710.407
calcium ion transportGO:00068161590.405
leukocyte proliferationGO:00706611720.400
Mouse
mapk cascadeGO:00001652810.398
Mouse
leukocyte differentiationGO:00025213420.397
Mouse
positive regulation of t cell extravasationGO:200040920.391
release of sequestered calcium ion into cytosolGO:0051209420.391
positive regulation of t cell costimulationGO:200052520.390
regulation of cytokine secretionGO:0050707610.387
cytosolic calcium ion homeostasisGO:0051480700.386
cytokine secretionGO:0050663720.386
positive regulation of natural killer cell chemotaxisGO:200050310.382
thymic t cell selectionGO:0045061220.375
negative thymic t cell selectionGO:0045060120.372
membrane organizationGO:00610242450.371
positive regulation of dendritic cell chemotaxisGO:200051010.370
positive regulation of immunological synapse formationGO:200052210.359
chemokine mediated signaling pathwayGO:0070098170.358
positive regulation of cytokine productionGO:00018191740.355
helper t cell chemotaxisGO:003570410.350
divalent inorganic cation transportGO:00725111780.346
positive regulation of protein phosphorylationGO:00019342420.341
cd8 positive alpha beta t cell extravasationGO:003569730.339
positive regulation of secretionGO:00510471300.330
single organism cell adhesionGO:00986021560.326
Human Mouse
metal ion homeostasisGO:00550651890.325
positive regulation of leukocyte differentiationGO:1902107860.322
Mouse
regulation of membrane potentialGO:00423911920.316
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.314
t cell differentiation in thymusGO:0033077770.314
myeloid leukocyte migrationGO:0097529570.313
Mouse
neuronal action potentialGO:0019228540.309
cation transportGO:00068123990.309
regulation of map kinase activityGO:00434051200.308
interleukin 1 productionGO:0032612310.305
regulation of response to woundingGO:19030341890.305
positive regulation of monocyte extravasationGO:200043910.301
cell surface pattern recognition receptor signaling pathwayGO:000275220.301
positive regulation of protein secretionGO:0050714520.300
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formationGO:200052610.300
humoral immune responseGO:0006959570.292
blood vessel morphogenesisGO:00485142850.290
Mouse
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.286
positive regulation of t cell differentiationGO:0045582520.286
purine containing compound metabolic processGO:00725213110.284
regulation of dendritic cell dendrite assemblyGO:200054720.284
exocytosisGO:00068871210.283
positive regulation of lymphocyte proliferationGO:0050671700.283
Mouse
positive regulation of t cell receptor signaling pathwayGO:005086240.279
regulation of alpha beta t cell proliferationGO:0046640180.277
dendritic cell dendrite assemblyGO:009702620.277
cellular ion homeostasisGO:00068731650.276
regulation of protein transportGO:00512231630.276
small gtpase mediated signal transductionGO:0007264970.276
Mouse
t helper 17 cell chemotaxisGO:003570510.273
regulation of chemotaxisGO:0050920530.272
regulation of granulocyte chemotaxisGO:0071622170.271
regulation of immune complex clearance by monocytes and macrophagesGO:009026420.270
positive regulation of hematopoietic stem cell migrationGO:200047310.269
eosinophil activation involved in immune responseGO:000227810.269
detection of yeastGO:000187920.266
positive regulation of lymphocyte migrationGO:2000403110.265
positive regulation of t cell activationGO:00508701010.265
Mouse
regulation of lymphocyte proliferationGO:00506701170.264
Mouse
t helper 1 cell cytokine productionGO:003574410.263
cell adhesionGO:00071553290.262
Human Mouse Fly
regulation of neutrophil migrationGO:1902622140.262
calcium ion homeostasisGO:00550741270.260
regulation of ion transportGO:00432692150.257
positive regulation of lymphocyte activationGO:00512511400.255
Mouse
t cell mediated immunityGO:0002456500.254
cellular metal ion homeostasisGO:00068751510.252
activation of innate immune responseGO:0002218560.248
negative regulation of secretionGO:0051048610.247
regulation of defense responseGO:00313472330.247
monocyte extravasationGO:003569620.246
regulation of alpha beta t cell activationGO:0046634530.244
protein secretionGO:00093061110.243
lymphocyte mediated immunityGO:00024491390.242
serotonin secretion by mast cellGO:000255210.238
regulation of monocyte extravasationGO:200043720.238
protein catabolic processGO:00301632210.236
t cell proliferationGO:00420981200.235
Mouse
divalent metal ion transportGO:00708381720.233
cdc42 protein signal transductionGO:003248800.231
second messenger mediated signalingGO:0019932730.231
Mouse
positive regulation of immune effector processGO:00026991070.230
negative regulation of cell activationGO:00508661110.229
maintenance of locationGO:0051235890.229
ribose phosphate metabolic processGO:00196932910.227
response to molecule of fungal originGO:000223840.225
regulation of secretion by cellGO:19035302490.225
divalent inorganic cation homeostasisGO:00725071380.225
cellular amine metabolic processGO:0044106440.224
regulation of lymphocyte differentiationGO:00456191070.224
t helper 1 type immune responseGO:0042088250.223
regulation of t helper 1 type immune responseGO:0002825170.222
regulation of natural killer cell chemotaxisGO:200050110.221
positive regulation of t helper 2 cell cytokine productionGO:200055330.221
interleukin 1 beta productionGO:0032611300.220
regulation of antigen receptor mediated signaling pathwayGO:0050854290.220
positive regulation of b cell chemotaxisGO:200053820.220
positive regulation of immunoglobulin production in mucosal tissueGO:200055810.216
regulation of establishment of protein localizationGO:00702011810.216
neutrophil migrationGO:1990266370.215
Mouse
t cell receptor signaling pathwayGO:0050852460.214
purine ribonucleotide metabolic processGO:00091502900.210
positive regulation of behaviorGO:0048520400.210
t cell extravasationGO:007268340.209
positive regulation of cd4 positive alpha beta t cell proliferationGO:200056310.208
regulation of t helper 2 cell cytokine productionGO:200055130.207
regulation of immunological synapse formationGO:200052020.207
regulation of type 2 immune responseGO:0002828180.205
cellular divalent inorganic cation homeostasisGO:00725031270.205
positive regulation of alpha beta t cell activationGO:0046635390.204
innate immune response activating signal transductionGO:0002758500.202
positive regulation of inflammatory responseGO:0050729470.202
cation homeostasisGO:00550802120.199
hematopoietic stem cell migrationGO:003570110.199
lymphocyte chemotaxisGO:0048247100.198
immune complex clearanceGO:000243420.195
regulation of leukocyte differentiationGO:19021051590.194
Mouse
positive regulation of map kinase activityGO:0043406840.193
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.193
regulation of cellular amine metabolic processGO:0033238200.192
calcium mediated signalingGO:0019722460.190
Mouse
t cell activation involved in immune responseGO:0002286430.189
macromolecule catabolic processGO:00090572810.187
regulation of calcium ion transportGO:0051924690.186
positive regulation of lymphocyte differentiationGO:0045621610.185
ras protein signal transductionGO:0007265770.183
Mouse
regulation of leukocyte proliferationGO:00706631210.180
Mouse
positive regulation of ion transportGO:0043270650.179
regulation of myeloid cell apoptotic processGO:0033032190.177
lymphocyte migrationGO:0072676260.177
Mouse
regulation of protein localizationGO:00328802310.177
cytoplasmic transportGO:00164822340.175
leukocyte degranulationGO:0043299270.174
dendritic cell migrationGO:0036336120.173
microglial cell activation involved in immune responseGO:000228210.172
multicellular organismal signalingGO:0035637910.169
innate immune response activating cell surface receptor signaling pathwayGO:000222040.169
cellular homeostasisGO:00197252400.167
ribonucleotide metabolic processGO:00092592910.166
regulation of dendritic cell antigen processing and presentationGO:000260470.164
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.163
positive regulation of t cell proliferationGO:0042102520.162
Mouse
regulation of t cell differentiationGO:0045580830.161
regulation of epithelial cell proliferationGO:00506781410.161
defense response to gram positive bacteriumGO:0050830500.161
regulation of t cell proliferationGO:0042129920.161
Mouse
dendritic cell differentiationGO:0097028260.159
regulation of cell shapeGO:0008360390.159
multicellular organismal homeostasisGO:00488711640.158
Mouse
positive regulation of interleukin 12 productionGO:0032735210.157
regulation of cell adhesionGO:00301551540.156
Mouse
alpha beta t cell differentiationGO:0046632690.155
negative regulation of exocytosisGO:0045920120.155
detection of biotic stimulusGO:0009595100.154
mature natural killer cell chemotaxisGO:003578210.153
positive regulation of transferase activityGO:00513471670.152
regulation of secretionGO:00510462740.152
chemotaxisGO:00069352470.150
Mouse Fly
regulation of reactive oxygen species biosynthetic processGO:190342620.150
positive regulation of t helper 1 cell differentiationGO:004562740.150
regulation of toll like receptor 4 signaling pathwayGO:003414340.149
regulation of ras protein signal transductionGO:00465781140.148
Mouse
production of molecular mediator of immune responseGO:00024401030.148
positive regulation of tumor necrosis factor productionGO:0032760300.147
detection of stimulusGO:0051606840.147
positive regulation of innate immune responseGO:0045089800.147
positive regulation of adaptive immune responseGO:0002821610.146
t cell chemotaxisGO:001081860.145
regulation of nucleotide catabolic processGO:00308111220.145
positive regulation of secretion by cellGO:19035321140.145
regulation of dendritic cell chemotaxisGO:200050810.145
astrocyte cell migrationGO:004361530.144
activation of immune responseGO:00022531380.142
positive regulation of type 2 immune responseGO:000283090.142
response to lipopolysaccharideGO:00324961280.141
regulation of t cell mediated immunityGO:0002709340.141
negative t cell selectionGO:0043383130.141
regulation of protein kinase activityGO:00458592320.140
regulation of t cell extravasationGO:200040730.140
positive regulation of natural killer cell mediated cytotoxicityGO:0045954160.139
purine ribonucleoside triphosphate metabolic processGO:00092052200.138
alpha beta t cell proliferationGO:0046633210.138
t cell migrationGO:0072678190.138
Mouse
single organismal cell cell adhesionGO:00163371310.137
Human Mouse
cellular extravasationGO:0045123170.136
Mouse
nucleoside catabolic processGO:00091642060.136
cd4 positive alpha beta t cell proliferationGO:003573920.136
pattern recognition receptor signaling pathwayGO:0002221470.135
inflammatory responseGO:00069542440.135
Mouse
wound healingGO:00420601570.135
Fly
positive regulation of protein modification processGO:00314012990.134
purine ribonucleoside triphosphate catabolic processGO:00092071990.134
reactive nitrogen species metabolic processGO:200105700.133
positive regulation of t helper 1 type immune responseGO:0002827120.132
myeloid leukocyte mediated immunityGO:0002444420.131
regulation of tumor necrosis factor productionGO:0032680490.131
regulation of actin filament based processGO:0032970990.131
regulation of purine nucleotide metabolic processGO:19005421690.130
positive regulation of natural killer cell mediated immunityGO:0002717160.129
purine nucleotide metabolic processGO:00061633020.127
developmental growth involved in morphogenesisGO:00605601380.127
Fly
amine metabolic processGO:0009308450.127
eosinophil degranulationGO:004330810.126
regulation of cellular component biogenesisGO:00440871810.125
Fly
regulation of exocytosisGO:0017157610.125
purine ribonucleoside metabolic processGO:00461282410.125
cell recognitionGO:0008037830.123
regulated secretory pathwayGO:0045055320.123
extrinsic apoptotic signaling pathwayGO:00971911260.123
Mouse
positive regulation of cytosolic calcium ion concentrationGO:0007204650.121
muscle tissue developmentGO:00605373080.121
Mouse
t cell selectionGO:0045058340.119
regulation of eosinophil degranulationGO:004330910.119
positive regulation of glycoprotein metabolic processGO:190302060.119
antigen receptor mediated signaling pathwayGO:0050851640.119
cell type specific apoptotic processGO:00972852680.119
cell killingGO:0001906670.118
b cell chemotaxisGO:003575430.118
t helper 2 cell cytokine productionGO:003574540.117
regulation of cellular ketone metabolic processGO:0010565660.116
positive regulation of antigen receptor mediated signaling pathwayGO:005085790.115
regulation of cytokine biosynthetic processGO:0042035590.113
regulation of endocytosisGO:0030100690.113
Mouse
positive regulation of interferon gamma productionGO:0032729390.112
signal transduction in absence of ligandGO:0038034550.111
Mouse
t cell costimulationGO:0031295140.110
cellular response to lipidGO:00713961450.110
regulation of immunoglobulin production in mucosal tissueGO:200055710.109
organonitrogen compound catabolic processGO:19015652640.109
apoptotic signaling pathwayGO:00971903060.109
Mouse
positive regulation of programmed cell deathGO:00430682180.108
aromatic compound catabolic processGO:00194392860.108
regulation of regulated secretory pathwayGO:1903305200.108
negative regulation of immune effector processGO:0002698550.107
muscle cell differentiationGO:00426922610.107
Mouse
regulation of phospholipase c activityGO:190027430.107
granulocyte activationGO:0036230100.106
positive regulation of alpha beta t cell proliferationGO:0046641120.106
lymphocyte costimulationGO:0031294150.106
regulation of cd4 positive alpha beta t cell proliferationGO:200056120.106
transmission of nerve impulseGO:0019226760.105
response to molecule of bacterial originGO:00022371430.105
developmental maturationGO:00217001930.104
purine nucleoside metabolic processGO:00422782410.104
cytokine mediated signaling pathwayGO:00192211150.104
negative regulation of multi organism processGO:0043901680.104
response to organonitrogen compoundGO:00102432460.103
organ or tissue specific immune responseGO:0002251130.103
positive regulation of cellular amino acid metabolic processGO:004576430.103
cytokine production involved in immune responseGO:0002367340.102
regulation of mapk cascadeGO:00434082480.102
interferon gamma productionGO:0032609670.102
b cell activationGO:00421131610.101
type 2 immune responseGO:0042092230.100
positive regulation of t helper 1 cell cytokine productionGO:200055610.100
nucleoside triphosphate catabolic processGO:00091432050.099
positive regulation of cell deathGO:00109422240.099
regulation of organelle organizationGO:00330432890.099
immune complex clearance by monocytes and macrophagesGO:000243620.097
positive regulation of cellular catabolic processGO:00313311480.097
positive regulation of cellular amine metabolic processGO:003324050.096
positive regulation of response to woundingGO:1903036660.096
regulation of cell killingGO:0031341400.096
regulation of hematopoietic stem cell migrationGO:200047110.095
regulation of protein serine threonine kinase activityGO:00719001570.095
nucleotide catabolic processGO:00091662170.095
cytokine biosynthetic processGO:0042089680.094
positive regulation of endocytosisGO:0045807420.094
positive regulation of phospholipase activityGO:001051830.094
negative regulation of intracellular signal transductionGO:19025321670.094
Mouse
purine nucleoside triphosphate metabolic processGO:00091442260.094
positive regulation of phagocytosisGO:0050766260.094
tolerance inductionGO:0002507140.093
germ cell developmentGO:00072811850.093
Fly
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.092
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.092
Mouse
homeostasis of number of cellsGO:00488722100.092
regulation of rho gtpase activityGO:0032319580.092
ribonucleoside catabolic processGO:00424542060.091
toll like receptor signaling pathwayGO:0002224380.091
immunoglobulin production in mucosal tissueGO:000242630.091
organic cyclic compound catabolic processGO:19013612950.090
regulation of homeostatic processGO:00328441820.090
Mouse
ensheathment of neuronsGO:0007272760.088
nucleoside triphosphate metabolic processGO:00091412300.087
regulation of inflammatory responseGO:00507271470.087
regulation of cell projection organizationGO:00313442060.086
receptor mediated endocytosisGO:0006898510.086
ribonucleoside metabolic processGO:00091192450.086
cellular chemical homeostasisGO:00550822150.086
regulation of gtp catabolic processGO:00331241130.085
detection of fungusGO:001604620.085
positive regulation of immune complex clearance by monocytes and macrophagesGO:009026520.084
positive regulation of lymphocyte mediated immunityGO:0002708620.084
positive regulation of epithelial cell proliferationGO:0050679680.084
interleukin 1 beta secretionGO:0050702160.084
nucleotide metabolic processGO:00091173320.083
leukocyte apoptotic processGO:0071887710.083
eosinophil mediated immunityGO:000244710.083
negative regulation of myeloid leukocyte mediated immunityGO:000288770.082
positive regulation of gtp catabolic processGO:0033126850.082
positive regulation of alpha beta t cell differentiationGO:0046638280.082
microglial cell activationGO:000177430.082
positive regulation of angiogenesisGO:0045766460.082
forebrain developmentGO:00309003020.082
glycoprotein biosynthetic processGO:0009101890.082
response to interferon gammaGO:0034341340.081
regulation of cellular catabolic processGO:00313292420.081
sensory perceptionGO:00076002450.081
branching involved in mammary gland duct morphogenesisGO:0060444270.081
ribonucleotide catabolic processGO:00092612080.080
negative regulation of leukocyte mediated immunityGO:0002704290.080
regulation of b cell proliferationGO:0030888390.079
positive regulation of homeostatic processGO:0032846640.079
Mouse
interleukin 12 productionGO:0032615320.079
positive regulation of protein kinase activityGO:00458601440.079
positive regulation of mapk cascadeGO:00434101700.079
t helper cell differentiationGO:0042093280.079
nucleobase containing small molecule metabolic processGO:00550863520.079
sensory perception of painGO:0019233470.078
regulation of lymphocyte migrationGO:2000401140.078
cell cell recognitionGO:0009988440.078
regulation of cellular response to stressGO:00801351590.077
regulation of nucleotide metabolic processGO:00061401690.077
positive regulation of protein transportGO:0051222930.077
glycosyl compound metabolic processGO:19016572460.077
ribonucleoside triphosphate catabolic processGO:00092031990.076
regulation of natural killer cell mediated immunityGO:0002715190.076
peptidyl tyrosine phosphorylationGO:00181081430.076
fc receptor mediated inhibitory signaling pathwayGO:000277410.076
positive regulation of gliogenesisGO:0014015270.075
gliogenesisGO:00420631410.075
Mouse
purine nucleotide catabolic processGO:00061952110.074
dendritic cell antigen processing and presentationGO:000246870.074
regulation of leukocyte apoptotic processGO:2000106560.073
cellular response to molecule of fungal originGO:007122620.073
regulation of cytokine production involved in immune responseGO:0002718260.073
regulation of cellular amino acid metabolic processGO:000652150.073
regulation of reactive oxygen species metabolic processGO:2000377400.073
purine nucleoside triphosphate catabolic processGO:00091462030.073
positive regulation of dendritic cell antigen processing and presentationGO:000260670.072
positive regulation of erk1 and erk2 cascadeGO:0070374470.072
angiogenesisGO:00015252010.072
phagocytosisGO:0006909660.071
Mouse Fly
positive regulation of protein serine threonine kinase activityGO:00719021060.071
regulation of intracellular transportGO:00323861590.070
regulation of acute inflammatory responseGO:0002673270.070
positive regulation of cell developmentGO:00107202370.070
positive regulation of phospholipase c activityGO:001086320.070
epithelial tube morphogenesisGO:00605623030.070
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.069
Mouse
positive regulation of cytokine biosynthetic processGO:0042108400.069
positive regulation of hydrolase activityGO:00513451480.068
nucleoside phosphate catabolic processGO:19012922220.068
negative regulation of secretion by cellGO:1903531540.068
cellular response to transforming growth factor beta stimulusGO:0071560880.068
Mouse
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.066
epithelial cell proliferationGO:00506731740.066
regulation of rho protein signal transductionGO:0035023710.066
Mouse
axonogenesisGO:00074092740.066
Fly
guanosine containing compound metabolic processGO:19010681440.066
neuron apoptotic processGO:00514021420.065
immunoglobulin transcytosis in epithelial cellsGO:000241420.065
peptidyl tyrosine modificationGO:00182121450.064
purinergic nucleotide receptor signaling pathwayGO:003559030.064
positive regulation of t cell mediated immunityGO:0002711240.064
regulation of metal ion transportGO:00109591060.063
carbohydrate derivative biosynthetic processGO:19011371830.063
inflammatory cell apoptotic processGO:0006925110.062
cellular response to molecule of bacterial originGO:0071219830.062
anatomical structure homeostasisGO:00602491450.062
Mouse
cell maturationGO:00484691270.062
positive regulation of lipid metabolic processGO:0045834400.062
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.062
nucleoside metabolic processGO:00091162460.061
myeloid cell apoptotic processGO:0033028220.061
purine ribonucleoside catabolic processGO:00461302050.060
branching morphogenesis of an epithelial tubeGO:00487541590.060
osteoclast differentiationGO:0030316620.059
Mouse
carbohydrate derivative catabolic processGO:19011362310.059
nucleoside phosphate metabolic processGO:00067533380.059
positive regulation of rho gtpase activityGO:0032321410.059
negative regulation of cell migrationGO:0030336590.059
Fly
regulation of interferon gamma productionGO:0032649570.059
cellular response to biotic stimulusGO:0071216920.058
cellular ketone metabolic processGO:0042180840.058
natural killer cell mediated cytotoxicityGO:0042267290.058
response to transforming growth factor betaGO:0071559880.058
Mouse
cd4 positive alpha beta t cell activationGO:0035710450.057
negative regulation of defense responseGO:0031348770.057
phosphatidylinositol mediated signalingGO:0048015410.057
regulation of leukocyte degranulationGO:0043300200.056

Itgax disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.179
musculoskeletal system diseaseDOID:1700.179
bone inflammation diseaseDOID:334200.116
bone diseaseDOID:008000100.116
rheumatoid arthritisDOID:714800.116
connective tissue diseaseDOID:6500.116
arthritisDOID:84800.116