| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.975 | Mouse |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.942 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.938 | Mouse |
| defense response to other organism | GO:0098542 | 197 | 0.933 | Mouse |
| regulation of cytokine production | GO:0001817 | 266 | 0.911 | |
| immune effector process | GO:0002252 | 321 | 0.896 | Human Mouse |
| regulation of innate immune response | GO:0045088 | 91 | 0.896 | |
| immune response activating cell surface receptor signaling pathway | GO:0002429 | 72 | 0.887 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.884 | Mouse |
| regulation of cell activation | GO:0050865 | 289 | 0.864 | |
| neuron projection guidance | GO:0097485 | 141 | 0.826 | Fly |
| negative regulation of immune system process | GO:0002683 | 209 | 0.818 | |
| chemotaxis | GO:0006935 | 247 | 0.813 | Mouse Fly |
| myeloid cell differentiation | GO:0030099 | 233 | 0.813 | Mouse |
| t cell activation | GO:0042110 | 289 | 0.801 | |
| cytokine production | GO:0001816 | 319 | 0.792 | |
| cellular extravasation | GO:0045123 | 17 | 0.779 | Mouse |
| leukocyte migration | GO:0050900 | 124 | 0.735 | Mouse |
| defense response to gram positive bacterium | GO:0050830 | 50 | 0.729 | |
| leukocyte activation involved in immune response | GO:0002366 | 126 | 0.728 | Human |
| antigen receptor mediated signaling pathway | GO:0050851 | 64 | 0.723 | |
| positive regulation of lymphocyte activation | GO:0051251 | 140 | 0.717 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 145 | 0.707 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.707 | Mouse |
| regulation of t cell proliferation | GO:0042129 | 92 | 0.688 | |
| positive regulation of cytokine production | GO:0001819 | 174 | 0.676 | |
| positive regulation of cell migration | GO:0030335 | 109 | 0.669 | Mouse |
| positive regulation of t cell activation | GO:0050870 | 101 | 0.666 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.651 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.650 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.630 | Mouse |
| regulation of leukocyte mediated immunity | GO:0002703 | 104 | 0.620 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.598 | |
| regulation of cell migration | GO:0030334 | 219 | 0.596 | Mouse Fly |
| rho protein signal transduction | GO:0007266 | 32 | 0.595 | Mouse |
| lymphocyte differentiation | GO:0030098 | 242 | 0.592 | |
| b cell activation | GO:0042113 | 161 | 0.591 | |
| immune response activating signal transduction | GO:0002757 | 116 | 0.591 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.589 | Fly |
| immune response regulating cell surface receptor signaling pathway | GO:0002768 | 80 | 0.579 | |
| myeloid leukocyte activation | GO:0002274 | 83 | 0.564 | |
| regulation of adaptive immune response | GO:0002819 | 90 | 0.564 | |
| t cell differentiation | GO:0030217 | 174 | 0.559 | |
| inflammatory response | GO:0006954 | 244 | 0.554 | Mouse |
| innate immune response | GO:0045087 | 157 | 0.543 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.537 | |
| cytokine mediated signaling pathway | GO:0019221 | 115 | 0.535 | |
| adaptive immune response | GO:0002250 | 155 | 0.530 | |
| activation of immune response | GO:0002253 | 138 | 0.527 | |
| negative thymic t cell selection | GO:0045060 | 12 | 0.527 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.521 | Mouse |
| digestive tract development | GO:0048565 | 190 | 0.515 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.509 | |
| lymphocyte migration | GO:0072676 | 26 | 0.509 | Mouse |
| cell activation involved in immune response | GO:0002263 | 126 | 0.503 | Human |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.499 | |
| immune response regulating signaling pathway | GO:0002764 | 125 | 0.497 | |
| regionalization | GO:0003002 | 337 | 0.494 | |
| membrane organization | GO:0061024 | 245 | 0.488 | Human |
| axon guidance | GO:0007411 | 141 | 0.478 | Fly |
| granulocyte migration | GO:0097530 | 43 | 0.477 | Mouse |
| angiogenesis | GO:0001525 | 201 | 0.467 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.462 | |
| regulation of defense response | GO:0031347 | 233 | 0.449 | |
| granulocyte chemotaxis | GO:0071621 | 39 | 0.444 | Mouse |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.441 | |
| positive regulation of monocyte extravasation | GO:2000439 | 1 | 0.438 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.435 | |
| positive regulation of t cell extravasation | GO:2000409 | 2 | 0.428 | |
| t cell receptor signaling pathway | GO:0050852 | 46 | 0.426 | |
| peptidyl tyrosine modification | GO:0018212 | 145 | 0.425 | |
| cell fate commitment | GO:0045165 | 210 | 0.421 | |
| positive regulation of cytokine biosynthetic process | GO:0042108 | 40 | 0.421 | |
| alpha beta t cell activation | GO:0046631 | 91 | 0.416 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.414 | |
| regulation of cytokine biosynthetic process | GO:0042035 | 59 | 0.412 | |
| cell chemotaxis | GO:0060326 | 81 | 0.410 | Mouse |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 2 | 0.405 | |
| leukocyte cell cell adhesion | GO:0007159 | 14 | 0.404 | |
| regulation of t cell costimulation | GO:2000523 | 2 | 0.401 | |
| positive regulation of cd8 positive alpha beta t cell extravasation | GO:2000451 | 2 | 0.398 | |
| t cell proliferation | GO:0042098 | 120 | 0.397 | |
| negative regulation of synapse assembly | GO:0051964 | 3 | 0.391 | Fly |
| cellular amine metabolic process | GO:0044106 | 44 | 0.390 | |
| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 45 | 0.388 | |
| regulation of interferon gamma production | GO:0032649 | 57 | 0.385 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.379 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.379 | |
| myeloid leukocyte mediated immunity | GO:0002444 | 42 | 0.371 | |
| pattern recognition receptor signaling pathway | GO:0002221 | 47 | 0.371 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.369 | |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.367 | |
| mapk cascade | GO:0000165 | 281 | 0.366 | Mouse |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.366 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.359 | Mouse |
| neutrophil migration | GO:1990266 | 37 | 0.357 | Mouse |
| response to growth factor | GO:0070848 | 198 | 0.355 | Mouse |
| cytokine biosynthetic process | GO:0042089 | 68 | 0.346 | |
| t cell selection | GO:0045058 | 34 | 0.346 | |
| regulation of tumor necrosis factor production | GO:0032680 | 49 | 0.344 | |
| erk1 and erk2 cascade | GO:0070371 | 77 | 0.344 | Mouse |
| negative regulation of innate immune response | GO:0045824 | 17 | 0.341 | |
| exocytosis | GO:0006887 | 121 | 0.339 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.338 | |
| regulation of leukocyte proliferation | GO:0070663 | 121 | 0.333 | |
| axonogenesis | GO:0007409 | 274 | 0.324 | Fly |
| positive regulation of hematopoietic stem cell migration | GO:2000473 | 1 | 0.316 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.314 | |
| extrinsic apoptotic signaling pathway in absence of ligand | GO:0097192 | 55 | 0.312 | Mouse |
| negative regulation of cell activation | GO:0050866 | 111 | 0.311 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.311 | Mouse |
| positive regulation of t cell proliferation | GO:0042102 | 52 | 0.309 | |
| regulation of rho protein signal transduction | GO:0035023 | 71 | 0.308 | Mouse |
| cell adhesion | GO:0007155 | 329 | 0.305 | |
| t cell differentiation in thymus | GO:0033077 | 77 | 0.304 | |
| positive regulation of lymphocyte proliferation | GO:0050671 | 70 | 0.295 | |
| regulation of leukocyte apoptotic process | GO:2000106 | 56 | 0.291 | |
| neutrophil chemotaxis | GO:0030593 | 36 | 0.291 | Mouse |
| single organism cell adhesion | GO:0098602 | 156 | 0.285 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.284 | |
| interferon gamma production | GO:0032609 | 67 | 0.284 | |
| ameboidal type cell migration | GO:0001667 | 128 | 0.279 | |
| cd8 positive alpha beta t cell extravasation | GO:0035697 | 3 | 0.275 | |
| regulation of monocyte extravasation | GO:2000437 | 2 | 0.274 | |
| myeloid leukocyte migration | GO:0097529 | 57 | 0.273 | Mouse |
| neuron migration | GO:0001764 | 122 | 0.270 | Mouse |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.270 | Fly |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 77 | 0.269 | |
| eosinophil degranulation | GO:0043308 | 1 | 0.266 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.265 | |
| gland development | GO:0048732 | 330 | 0.264 | Fly |
| cytosolic calcium ion transport | GO:0060401 | 48 | 0.263 | |
| regulation of cd8 positive alpha beta t cell extravasation | GO:2000449 | 3 | 0.263 | |
| t cell extravasation | GO:0072683 | 4 | 0.260 | |
| regulation of antigen receptor mediated signaling pathway | GO:0050854 | 29 | 0.257 | |
| positive regulation of neutrophil chemotaxis | GO:0090023 | 12 | 0.256 | |
| negative regulation of growth | GO:0045926 | 99 | 0.253 | Fly |
| stem cell differentiation | GO:0048863 | 268 | 0.252 | |
| regulation of immunological synapse formation | GO:2000520 | 2 | 0.251 | |
| regulation of neutrophil migration | GO:1902622 | 14 | 0.251 | |
| germ cell development | GO:0007281 | 185 | 0.249 | Fly |
| negative regulation of defense response | GO:0031348 | 77 | 0.249 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.246 | |
| cell killing | GO:0001906 | 67 | 0.240 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.237 | |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002822 | 87 | 0.237 | |
| forebrain development | GO:0030900 | 302 | 0.237 | |
| positive regulation of chemotaxis | GO:0050921 | 38 | 0.237 | |
| positive regulation of t cell receptor signaling pathway | GO:0050862 | 4 | 0.232 | |
| single organismal cell cell adhesion | GO:0016337 | 131 | 0.230 | |
| negative regulation of eosinophil degranulation | GO:0043310 | 1 | 0.229 | |
| regulation of cell adhesion | GO:0030155 | 154 | 0.229 | |
| positive regulation of innate immune response | GO:0045089 | 80 | 0.229 | |
| leukocyte chemotaxis | GO:0030595 | 69 | 0.229 | Mouse |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.228 | |
| positive regulation of calcium mediated signaling | GO:0050850 | 15 | 0.226 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.226 | |
| regulation of inflammatory response | GO:0050727 | 147 | 0.221 | |
| negative regulation of cytokine production | GO:0001818 | 84 | 0.219 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.219 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.218 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.218 | |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.214 | |
| hematopoietic stem cell migration | GO:0035701 | 1 | 0.209 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.209 | |
| cell substrate adhesion | GO:0031589 | 130 | 0.208 | Human Mouse |
| cytokine metabolic process | GO:0042107 | 71 | 0.207 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.205 | Mouse |
| regulation of cell motility | GO:2000145 | 236 | 0.199 | Mouse Fly |
| regulation of lymphocyte proliferation | GO:0050670 | 117 | 0.197 | |
| b cell activation involved in immune response | GO:0002312 | 50 | 0.195 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.195 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 86 | 0.194 | Mouse |
| erythrocyte differentiation | GO:0030218 | 88 | 0.194 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.192 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.191 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.189 | Mouse |
| motor neuron axon guidance | GO:0008045 | 26 | 0.187 | |
| regulation of t cell extravasation | GO:2000407 | 3 | 0.187 | |
| positive regulation of leukocyte proliferation | GO:0070665 | 73 | 0.187 | |
| eosinophil activation | GO:0043307 | 1 | 0.185 | |
| dna metabolic process | GO:0006259 | 303 | 0.185 | |
| amine metabolic process | GO:0009308 | 45 | 0.184 | |
| muscle tissue development | GO:0060537 | 308 | 0.183 | Mouse |
| homeostasis of number of cells | GO:0048872 | 210 | 0.180 | |
| positive regulation of dendritic cell chemotaxis | GO:2000510 | 1 | 0.180 | |
| positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation | GO:2000721 | 2 | 0.180 | Mouse |
| negative regulation of nervous system development | GO:0051961 | 156 | 0.178 | Fly |
| t helper 1 type immune response | GO:0042088 | 25 | 0.178 | |
| chemokine mediated signaling pathway | GO:0070098 | 17 | 0.177 | |
| positive regulation of defense response | GO:0031349 | 124 | 0.177 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.175 | Mouse |
| cytokine secretion | GO:0050663 | 72 | 0.175 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.175 | |
| regulation of alpha beta t cell proliferation | GO:0046640 | 18 | 0.174 | |
| positive t cell selection | GO:0043368 | 23 | 0.173 | |
| positive regulation of cell motility | GO:2000147 | 116 | 0.171 | Mouse |
| defense response to virus | GO:0051607 | 68 | 0.170 | Mouse |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.170 | |
| toll like receptor 7 signaling pathway | GO:0034154 | 4 | 0.170 | |
| regulation of cytokine secretion | GO:0050707 | 61 | 0.169 | |
| leukocyte apoptotic process | GO:0071887 | 71 | 0.169 | |
| innate immune response activating signal transduction | GO:0002758 | 50 | 0.168 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.166 | |
| positive regulation of immunological synapse formation | GO:2000522 | 1 | 0.164 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 71 | 0.163 | |
| signal transduction in absence of ligand | GO:0038034 | 55 | 0.163 | Mouse |
| t helper 17 cell chemotaxis | GO:0035705 | 1 | 0.160 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.159 | Mouse |
| negative regulation of multi organism process | GO:0043901 | 68 | 0.158 | |
| helper t cell chemotaxis | GO:0035704 | 1 | 0.157 | |
| organelle localization | GO:0051640 | 179 | 0.156 | |
| interleukin 12 secretion | GO:0072610 | 3 | 0.156 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.154 | |
| positive regulation of t cell costimulation | GO:2000525 | 2 | 0.152 | |
| regulation of protein localization | GO:0032880 | 231 | 0.151 | |
| wound healing | GO:0042060 | 157 | 0.151 | Fly |
| regulation of t cell activation | GO:0050863 | 170 | 0.151 | |
| digestive system development | GO:0055123 | 200 | 0.150 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.150 | |
| regulation of actin polymerization or depolymerization | GO:0008064 | 45 | 0.148 | |
| tissue remodeling | GO:0048771 | 102 | 0.147 | Mouse |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.145 | |
| myeloid cell homeostasis | GO:0002262 | 114 | 0.144 | |
| tissue homeostasis | GO:0001894 | 115 | 0.144 | Mouse |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.143 | Mouse |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.143 | |
| endocytosis | GO:0006897 | 168 | 0.143 | Mouse Fly |
| activation of mapk activity | GO:0000187 | 59 | 0.142 | |
| regulation of lymphocyte mediated immunity | GO:0002706 | 84 | 0.141 | |
| positive regulation of interferon gamma production | GO:0032729 | 39 | 0.139 | |
| regulation of neutrophil chemotaxis | GO:0090022 | 14 | 0.138 | |
| regulation of myeloid cell differentiation | GO:0045637 | 96 | 0.137 | Mouse |
| lymphocyte homeostasis | GO:0002260 | 64 | 0.135 | |
| negative regulation of homeostatic process | GO:0032845 | 71 | 0.132 | |
| regulation of hematopoietic stem cell migration | GO:2000471 | 1 | 0.131 | |
| cation homeostasis | GO:0055080 | 212 | 0.126 | |
| tumor necrosis factor production | GO:0032640 | 50 | 0.126 | |
| regulation of dendritic cell chemotaxis | GO:2000508 | 1 | 0.126 | |
| positive regulation of immune effector process | GO:0002699 | 107 | 0.123 | |
| phosphatidylinositol mediated signaling | GO:0048015 | 41 | 0.123 | |
| stem cell development | GO:0048864 | 219 | 0.122 | |
| gliogenesis | GO:0042063 | 141 | 0.121 | Mouse |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 83 | 0.120 | |
| regulation of immune complex clearance by monocytes and macrophages | GO:0090264 | 2 | 0.120 | |
| keratinocyte differentiation | GO:0030216 | 48 | 0.120 | |
| extracellular structure organization | GO:0043062 | 148 | 0.120 | Mouse |
| regulation of alpha beta t cell activation | GO:0046634 | 53 | 0.118 | |
| calcium ion transport into cytosol | GO:0060402 | 48 | 0.118 | |
| morphogenesis of a branching epithelium | GO:0061138 | 193 | 0.117 | |
| positive regulation of myeloid cell differentiation | GO:0045639 | 43 | 0.117 | Mouse |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.117 | |
| tumor necrosis factor superfamily cytokine production | GO:0071706 | 51 | 0.115 | |
| microglial cell activation involved in immune response | GO:0002282 | 1 | 0.114 | |
| positive regulation of monocyte chemotaxis | GO:0090026 | 2 | 0.113 | |
| bone remodeling | GO:0046849 | 53 | 0.113 | Mouse |
| regulation of dendritic cell apoptotic process | GO:2000668 | 3 | 0.112 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.111 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.111 | |
| positive regulation of granulocyte chemotaxis | GO:0071624 | 12 | 0.111 | |
| alpha beta t cell proliferation | GO:0046633 | 21 | 0.110 | |
| regulation of tumor necrosis factor superfamily cytokine production | GO:1903555 | 50 | 0.109 | |
| negative regulation of ras protein signal transduction | GO:0046580 | 18 | 0.108 | Mouse |
| regulation of protein secretion | GO:0050708 | 82 | 0.108 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.108 | |
| interspecies interaction between organisms | GO:0044419 | 83 | 0.108 | |
| protein localization to organelle | GO:0033365 | 185 | 0.107 | |
| immunoglobulin mediated immune response | GO:0016064 | 69 | 0.106 | |
| regulation of t cell differentiation | GO:0045580 | 83 | 0.106 | |
| positive regulation of adaptive immune response | GO:0002821 | 61 | 0.106 | |
| odontogenesis of dentin containing tooth | GO:0042475 | 66 | 0.105 | Mouse |
| positive regulation of t cell differentiation | GO:0045582 | 52 | 0.105 | |
| release of sequestered calcium ion into cytosol | GO:0051209 | 42 | 0.104 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.104 | Mouse |
| regulation of actin cytoskeleton organization | GO:0032956 | 84 | 0.104 | |
| bone resorption | GO:0045453 | 38 | 0.104 | Mouse |
| placenta development | GO:0001890 | 140 | 0.103 | Mouse |
| activation of innate immune response | GO:0002218 | 56 | 0.103 | |
| telencephalon cell migration | GO:0022029 | 55 | 0.102 | |
| negative regulation of leukocyte mediated immunity | GO:0002704 | 29 | 0.102 | |
| b cell differentiation | GO:0030183 | 78 | 0.102 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.101 | |
| regulation of chemotaxis | GO:0050920 | 53 | 0.099 | |
| regulated secretory pathway | GO:0045055 | 32 | 0.099 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 143 | 0.098 | |
| regulation of toll like receptor signaling pathway | GO:0034121 | 20 | 0.096 | |
| gastrulation | GO:0007369 | 116 | 0.096 | |
| negative regulation of immune effector process | GO:0002698 | 55 | 0.096 | |
| positive regulation of alpha beta t cell activation | GO:0046635 | 39 | 0.095 | |
| immune complex clearance | GO:0002434 | 2 | 0.094 | |
| positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002824 | 61 | 0.094 | |
| positive regulation of neutrophil migration | GO:1902624 | 12 | 0.094 | |
| natural killer cell activation | GO:0030101 | 44 | 0.094 | |
| interferon beta biosynthetic process | GO:0045350 | 4 | 0.093 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.093 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.092 | |
| leukocyte degranulation | GO:0043299 | 27 | 0.092 | |
| somatic diversification of immune receptors via germline recombination within a single locus | GO:0002562 | 51 | 0.092 | |
| monocyte extravasation | GO:0035696 | 2 | 0.091 | |
| reactive nitrogen species metabolic process | GO:2001057 | 0 | 0.091 | |
| lymphocyte activation involved in immune response | GO:0002285 | 93 | 0.091 | Human |
| regulation of eosinophil degranulation | GO:0043309 | 1 | 0.090 | |
| regulation of interleukin 6 production | GO:0032675 | 55 | 0.090 | |
| t cell activation involved in immune response | GO:0002286 | 43 | 0.088 | Human |
| glial cell differentiation | GO:0010001 | 131 | 0.088 | Mouse |
| blood coagulation | GO:0007596 | 76 | 0.086 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.086 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.086 | |
| negative regulation of t cell activation | GO:0050868 | 65 | 0.085 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.085 | |
| eosinophil activation involved in immune response | GO:0002278 | 1 | 0.085 | |
| alpha beta t cell differentiation involved in immune response | GO:0002293 | 30 | 0.084 | |
| regulation of vascular endothelial growth factor production | GO:0010574 | 13 | 0.083 | |
| immune complex clearance by monocytes and macrophages | GO:0002436 | 2 | 0.083 | |
| cell recognition | GO:0008037 | 83 | 0.083 | |
| phagocytosis | GO:0006909 | 66 | 0.082 | Mouse Fly |
| tolerance induction | GO:0002507 | 14 | 0.082 | |
| somatic diversification of immunoglobulins | GO:0016445 | 43 | 0.081 | |
| negative regulation of toll like receptor signaling pathway | GO:0034122 | 14 | 0.081 | |
| post embryonic organ development | GO:0048569 | 17 | 0.080 | Fly |
| interleukin 6 production | GO:0032635 | 58 | 0.080 | |
| isotype switching | GO:0045190 | 36 | 0.080 | |
| regulation of actin filament based process | GO:0032970 | 99 | 0.080 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.079 | Fly |
| regulation of t cell receptor signaling pathway | GO:0050856 | 21 | 0.079 | |
| morphogenesis of a branching structure | GO:0001763 | 203 | 0.079 | |
| cerebral cortex cell migration | GO:0021795 | 44 | 0.079 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.079 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.079 | Mouse |
| extracellular matrix organization | GO:0030198 | 147 | 0.078 | Mouse |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.078 | |
| somatic diversification of immunoglobulins involved in immune response | GO:0002208 | 36 | 0.078 | |
| inflammatory response to antigenic stimulus | GO:0002437 | 30 | 0.078 | |
| actin filament organization | GO:0007015 | 113 | 0.077 | |
| branching morphogenesis of an epithelial tube | GO:0048754 | 159 | 0.077 | |
| modulation of growth of symbiont involved in interaction with host | GO:0044144 | 19 | 0.077 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.077 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.077 | Mouse |
| cation transport | GO:0006812 | 399 | 0.076 | |
| positive regulation of behavior | GO:0048520 | 40 | 0.076 | |
| cellular response to lipid | GO:0071396 | 145 | 0.075 | |
| mesenchymal cell development | GO:0014031 | 93 | 0.075 | |
| leukocyte mediated cytotoxicity | GO:0001909 | 62 | 0.074 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.074 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 83 | 0.074 | |
| pallium development | GO:0021543 | 120 | 0.073 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.073 | Mouse |
| cell junction organization | GO:0034330 | 77 | 0.073 | Mouse |
| sequestering of calcium ion | GO:0051208 | 18 | 0.073 | |
| kidney development | GO:0001822 | 213 | 0.073 | Mouse |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.072 | |
| regulation of inflammatory response to antigenic stimulus | GO:0002861 | 21 | 0.072 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.072 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.072 | |
| negative regulation of type 2 immune response | GO:0002829 | 8 | 0.071 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.071 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.070 | Mouse |
| glycoprotein biosynthetic process | GO:0009101 | 89 | 0.070 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.069 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.069 | |
| regulation of type 2 immune response | GO:0002828 | 18 | 0.069 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.069 | Mouse |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 93 | 0.069 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.069 | |
| defense response to bacterium | GO:0042742 | 119 | 0.068 | |
| cerebral cortex development | GO:0021987 | 86 | 0.068 | |
| negative t cell selection | GO:0043383 | 13 | 0.068 | |
| protein secretion | GO:0009306 | 111 | 0.068 | |
| regulation of growth of symbiont in host | GO:0044126 | 19 | 0.068 | |
| endoderm development | GO:0007492 | 45 | 0.068 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.068 | |
| synapse organization | GO:0050808 | 125 | 0.068 | Fly |
| somatic recombination of immunoglobulin genes involved in immune response | GO:0002204 | 36 | 0.067 | |
| response to transforming growth factor beta | GO:0071559 | 88 | 0.067 | Mouse |
| cardiac muscle tissue development | GO:0048738 | 130 | 0.067 | |
| eosinophil mediated immunity | GO:0002447 | 1 | 0.066 | |
| skeletal system development | GO:0001501 | 356 | 0.066 | |
| production of molecular mediator of immune response | GO:0002440 | 103 | 0.066 | |
| glycoprotein metabolic process | GO:0009100 | 116 | 0.065 | |
| microtubule based process | GO:0007017 | 236 | 0.065 | |
| negative regulation of growth of symbiont involved in interaction with host | GO:0044146 | 19 | 0.064 | |
| forebrain cell migration | GO:0021885 | 58 | 0.064 | |
| cognition | GO:0050890 | 149 | 0.064 | Mouse |
| regulation of mast cell proliferation | GO:0070666 | 4 | 0.064 | |
| regulation of metal ion transport | GO:0010959 | 106 | 0.063 | |
| microglial cell activation | GO:0001774 | 3 | 0.063 | |
| t cell mediated immunity | GO:0002456 | 50 | 0.063 | |
| maintenance of location | GO:0051235 | 89 | 0.063 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 70 | 0.063 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.062 | |
| regulation of angiogenesis | GO:0045765 | 81 | 0.062 | |
| thymic t cell selection | GO:0045061 | 22 | 0.062 | |
| mesodermal cell migration | GO:0008078 | 4 | 0.062 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.062 | |
| cell growth | GO:0016049 | 130 | 0.061 | Fly |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.060 | |
| salivary gland development | GO:0007431 | 37 | 0.060 | Fly |
| neural precursor cell proliferation | GO:0061351 | 121 | 0.060 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.060 | |
| cell maturation | GO:0048469 | 127 | 0.060 | |
| protein catabolic process | GO:0030163 | 221 | 0.060 | |
| negative regulation of rho protein signal transduction | GO:0035024 | 7 | 0.060 | Mouse |
| intracellular receptor signaling pathway | GO:0030522 | 74 | 0.059 | |
| positive regulation of map kinase activity | GO:0043406 | 84 | 0.059 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.058 | |
| dna recombination | GO:0006310 | 92 | 0.058 | |
| regulation of t helper 1 type immune response | GO:0002825 | 17 | 0.058 | |
| microglia differentiation | GO:0014004 | 2 | 0.058 | Mouse |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 47 | 0.057 | |
| natural killer cell mediated immunity | GO:0002228 | 29 | 0.057 | |
| regulation of endopeptidase activity | GO:0052548 | 89 | 0.057 | |
| interleukin 12 production | GO:0032615 | 32 | 0.057 | |
| negative regulation of erk1 and erk2 cascade | GO:0070373 | 21 | 0.057 | |
| regulation of tumor necrosis factor biosynthetic process | GO:0042534 | 10 | 0.057 | |
| positive regulation of cytosolic calcium ion concentration | GO:0007204 | 65 | 0.056 | |
| positive regulation of peptidyl tyrosine phosphorylation | GO:0050731 | 61 | 0.056 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.056 | |
| segmentation | GO:0035282 | 93 | 0.056 | |
| regulation of exocytosis | GO:0017157 | 61 | 0.055 | |
| b cell mediated immunity | GO:0019724 | 71 | 0.055 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.055 | |
| cellular calcium ion homeostasis | GO:0006874 | 119 | 0.055 | |
| positive regulation of stress activated mapk cascade | GO:0032874 | 48 | 0.055 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.055 | |
| substrate adhesion dependent cell spreading | GO:0034446 | 30 | 0.054 | |
| alpha beta t cell activation involved in immune response | GO:0002287 | 31 | 0.054 | |
| establishment or maintenance of cell polarity | GO:0007163 | 86 | 0.054 | |
| interleukin 1 beta production | GO:0032611 | 30 | 0.054 | |
| positive regulation of myeloid leukocyte differentiation | GO:0002763 | 26 | 0.054 | Mouse |
| protein localization to nucleus | GO:0034504 | 121 | 0.054 | |
| regulation of leukocyte mediated cytotoxicity | GO:0001910 | 38 | 0.053 | |
| actin polymerization or depolymerization | GO:0008154 | 54 | 0.053 | |
| neutrophil mediated killing of gram positive bacterium | GO:0070946 | 2 | 0.053 | |
| regulation of erythrocyte differentiation | GO:0045646 | 23 | 0.053 | |
| positive regulation of antigen receptor mediated signaling pathway | GO:0050857 | 9 | 0.052 | |
| lipopolysaccharide mediated signaling pathway | GO:0031663 | 25 | 0.052 | |
| blood circulation | GO:0008015 | 195 | 0.052 | |
| positive regulation of leukocyte mediated immunity | GO:0002705 | 70 | 0.052 | |
| calcium mediated signaling | GO:0019722 | 46 | 0.052 | |
| interleukin 2 production | GO:0032623 | 33 | 0.051 | |
| positive regulation of leukocyte mediated cytotoxicity | GO:0001912 | 31 | 0.051 | |
| sequestering of metal ion | GO:0051238 | 19 | 0.051 | |
| regulation of endocytosis | GO:0030100 | 69 | 0.051 | Mouse |
| female gamete generation | GO:0007292 | 74 | 0.051 | Fly |
| positive regulation of osteoblast proliferation | GO:0033690 | 9 | 0.051 | Mouse |
| regulation of multi organism process | GO:0043900 | 111 | 0.050 | |
| t cell apoptotic process | GO:0070231 | 39 | 0.050 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.050 | |
| regulation of protein transport | GO:0051223 | 163 | 0.050 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.050 | |
| toll like receptor signaling pathway | GO:0002224 | 38 | 0.049 | |
| negative regulation of response to wounding | GO:1903035 | 77 | 0.049 | |
| regulation of cell killing | GO:0031341 | 40 | 0.049 | |
| regulation of ion homeostasis | GO:2000021 | 64 | 0.049 | |
| negative regulation of lymphocyte activation | GO:0051250 | 91 | 0.048 | |
| urogenital system development | GO:0001655 | 261 | 0.048 | Mouse |
| negative regulation of leukocyte differentiation | GO:1902106 | 51 | 0.048 | |
| positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation | GO:2000526 | 1 | 0.048 | |
| positive regulation of cell adhesion | GO:0045785 | 80 | 0.048 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 36 | 0.048 | |
| mesenchyme development | GO:0060485 | 152 | 0.048 | |
| somatic diversification of immune receptors | GO:0002200 | 53 | 0.047 | |
| mammary gland epithelium development | GO:0061180 | 65 | 0.047 | |
| protein kinase b signaling | GO:0043491 | 74 | 0.047 | |
| endomembrane system organization | GO:0010256 | 147 | 0.047 | |
| smooth muscle tissue development | GO:0048745 | 22 | 0.047 | Mouse |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.047 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 112 | 0.046 | Mouse |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.046 | |
| antigen processing and presentation | GO:0019882 | 47 | 0.046 | |
| regulation of calcium mediated signaling | GO:0050848 | 19 | 0.046 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.046 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.046 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.045 | Mouse |
| negative regulation of macrophage apoptotic process | GO:2000110 | 3 | 0.045 | |
| somatic recombination of immunoglobulin gene segments | GO:0016447 | 42 | 0.045 | |
| positive regulation of inflammatory response to antigenic stimulus | GO:0002863 | 11 | 0.045 | |
| myeloid dendritic cell differentiation | GO:0043011 | 16 | 0.045 | |
| acute inflammatory response | GO:0002526 | 41 | 0.045 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.045 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 62 | 0.045 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.045 | |
| t cell differentiation involved in immune response | GO:0002292 | 30 | 0.044 | |
| circulatory system process | GO:0003013 | 197 | 0.044 | |
| production of molecular mediator involved in inflammatory response | GO:0002532 | 21 | 0.044 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.044 | |
| positive regulation of b cell activation | GO:0050871 | 49 | 0.043 | |
| somatic cell dna recombination | GO:0016444 | 51 | 0.043 | |
| regulation of homotypic cell cell adhesion | GO:0034110 | 13 | 0.043 | |
| plasma membrane organization | GO:0007009 | 90 | 0.043 | |
| epithelial cell development | GO:0002064 | 159 | 0.043 | |
| growth of symbiont in host | GO:0044117 | 23 | 0.043 | |
| cd4 positive alpha beta t cell differentiation | GO:0043367 | 41 | 0.043 | |
| notch signaling pathway | GO:0007219 | 71 | 0.043 | |
| cell adhesion mediated by integrin | GO:0033627 | 18 | 0.043 | Mouse |