Mus musculus

396 known processes

Ptprc

protein tyrosine phosphatase, receptor type, C

(Aliases: loc,Cd45,CD45R,T200,Lyt-4,B220,Ly-5)

Ptprc biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of gamma delta t cell differentiationGO:004558861.000
negative regulation of adaptive immune responseGO:0002820251.000
regulation of mast cell activationGO:0033003210.999
Mouse
regulation of antigen receptor mediated signaling pathwayGO:0050854290.998
t cell receptor signaling pathwayGO:0050852460.998
Human
immune response activating cell surface receptor signaling pathwayGO:0002429720.996
negative thymic t cell selectionGO:0045060120.995
pattern recognition receptor signaling pathwayGO:0002221470.995
positive regulation of type iii hypersensitivityGO:000180530.995
activation of immune responseGO:00022531380.994
regulation of toll like receptor 2 signaling pathwayGO:003413530.994
regulation of cell activationGO:00508652890.990
cell activation involved in immune responseGO:00022631260.984
antigen receptor mediated signaling pathwayGO:0050851640.984
defense response to other organismGO:00985421970.983
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.981
immune response regulating signaling pathwayGO:00027641250.980
regulation of type iia hypersensitivityGO:000179640.978
t cell activationGO:00421102890.976
mast cell activationGO:0045576270.973
Mouse
adaptive immune responseGO:00022501550.972
immune response regulating cell surface receptor signaling pathwayGO:0002768800.966
positive regulation of dendritic cell apoptotic processGO:200067030.965
dephosphorylationGO:00163111290.963
positive regulation of type ii hypersensitivityGO:000289440.963
amine metabolic processGO:0009308450.962
leukocyte activation involved in immune responseGO:00023661260.962
cellular amine metabolic processGO:0044106440.960
lymphocyte differentiationGO:00300982420.959
positive regulation of cellular amine metabolic processGO:003324050.959
tyrosine phosphorylation of stat5 proteinGO:004250690.958
cd4 positive cd25 positive alpha beta regulatory t cell differentiationGO:000236140.958
positive regulation of lymphocyte activationGO:00512511400.953
immune response inhibiting signal transductionGO:000276540.953
positive regulation of mast cell activation involved in immune responseGO:0033008100.951
regulation of lymphocyte activationGO:00512492400.951
fc receptor mediated stimulatory signaling pathwayGO:000243140.951
antigen processing and presentation of peptide antigen via mhc class iGO:000247490.950
negative regulation of leukocyte proliferationGO:0070664460.948
cellular response to molecule of bacterial originGO:0071219830.947
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.947
blood coagulationGO:0007596760.946
immune response activating signal transductionGO:00027571160.940
regulation of b cell proliferationGO:0030888390.935
myeloid cell activation involved in immune responseGO:0002275340.934
positive regulation of regulatory t cell differentiationGO:004559140.932
positive regulation of leukocyte degranulationGO:0043302100.931
positive regulation of defense responseGO:00313491240.931
myeloid leukocyte mediated immunityGO:0002444420.930
integrin mediated signaling pathwayGO:0007229270.930
regulation of type ii hypersensitivityGO:000289240.930
immune effector processGO:00022523210.929
fc epsilon receptor signaling pathwayGO:003809530.925
myeloid leukocyte migrationGO:0097529570.925
regulation of leukocyte apoptotic processGO:2000106560.924
regulation of cellular amino acid metabolic processGO:000652150.922
t cell differentiation in thymusGO:0033077770.922
regulation of tumor necrosis factor productionGO:0032680490.919
negative regulation of b cell proliferationGO:0030889130.914
immune response inhibiting cell surface receptor signaling pathwayGO:000276730.912
positive regulation of myeloid leukocyte mediated immunityGO:0002888140.912
positive regulation of exocytosisGO:0045921200.910
alpha beta t cell differentiationGO:0046632690.906
regulation of response to woundingGO:19030341890.906
regulation of t cell receptor signaling pathwayGO:0050856210.906
negative regulation of intracellular signal transductionGO:19025321670.905
neutrophil migrationGO:1990266370.905
regulation of leukocyte proliferationGO:00706631210.904
regulation of dendritic cell apoptotic processGO:200066830.902
leukocyte apoptotic processGO:0071887710.894
regulation of intracellular transportGO:00323861590.894
platelet degranulationGO:000257660.889
innate immune response activating signal transductionGO:0002758500.889
positive regulation of cytokine productionGO:00018191740.888
mast cell degranulationGO:0043303190.888
regulation of alpha beta t cell differentiationGO:0046637350.888
cellular amino acid metabolic processGO:00065201030.887
positive regulation of cell activationGO:00508671580.885
regulation of mast cell activation involved in immune responseGO:0033006170.885
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.884
myeloid leukocyte activationGO:0002274830.876
Mouse
mast cell mediated immunityGO:0002448200.874
regulation of body fluid levelsGO:00508781620.873
regulation of inflammatory response to antigenic stimulusGO:0002861210.868
positive regulation of adaptive immune responseGO:0002821610.866
positive regulation of phagocytosisGO:0050766260.866
positive regulation of mast cell degranulationGO:0043306100.864
lysosome localizationGO:0032418200.862
regulation of regulated secretory pathwayGO:1903305200.862
negative regulation of synapse assemblyGO:005196430.860
leukocyte differentiationGO:00025213420.858
regulation of mast cell degranulationGO:0043304160.856
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.854
negative regulation of homeostatic processGO:0032845710.854
regulation of toll like receptor 4 signaling pathwayGO:003414340.851
b cell activationGO:00421131610.845
positive regulation of t cell activationGO:00508701010.843
positive regulation of regulated secretory pathwayGO:1903307100.834
myeloid cell homeostasisGO:00022621140.833
regulation of phagocytosisGO:0050764330.833
regulation of platelet activationGO:0010543170.832
regulated secretory pathwayGO:0045055320.824
actin cytoskeleton organizationGO:00300362200.822
negative regulation of cell activationGO:00508661110.820
leukocyte homeostasisGO:0001776790.819
regulation of tyrosine phosphorylation of stat5 proteinGO:004252280.817
gamma delta t cell differentiationGO:0042492110.816
regulation of cytokine production involved in immune responseGO:0002718260.814
positive regulation of hypersensitivityGO:000288570.814
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.814
Mouse
regulation of inflammatory responseGO:00507271470.807
positive regulation of b cell receptor signaling pathwayGO:005086140.797
calcium ion transportGO:00068161590.795
positive regulation of antigen receptor mediated signaling pathwayGO:005085790.792
t cell differentiationGO:00302171740.792
negative regulation of immune system processGO:00026832090.789
regulation of toll like receptor signaling pathwayGO:0034121200.781
cation transportGO:00068123990.778
negative regulation of map kinase activityGO:0043407340.778
homeostasis of number of cellsGO:00488722100.777
mast cell activation involved in immune responseGO:0002279200.775
negative regulation of toll like receptor 2 signaling pathwayGO:003413630.774
positive regulation of hydrolase activityGO:00513451480.771
regulation of calcium mediated signalingGO:0050848190.763
regulation of synaptic growth at neuromuscular junctionGO:000858240.763
positive regulation of cysteine type endopeptidase activityGO:2001056390.763
negative regulation of toll like receptor 4 signaling pathwayGO:003414430.758
granulocyte migrationGO:0097530430.757
negative regulation of toll like receptor signaling pathwayGO:0034122140.754
positive regulation of tyrosine phosphorylation of stat5 proteinGO:004252360.752
regulation of production of molecular mediator of immune responseGO:0002700650.743
positive regulation of cellular amino acid metabolic processGO:004576430.736
regulation of hypersensitivityGO:0002883100.730
alpha beta t cell activationGO:0046631910.725
positive regulation of immune effector processGO:00026991070.724
serotonin secretion by plateletGO:000255430.717
positive regulation of secretion by cellGO:19035321140.716
regulation of defense responseGO:00313472330.716
regulation of immunoglobulin mediated immune responseGO:0002889370.715
regulation of cd4 positive alpha beta t cell activationGO:2000514240.714
regulation of cellular ketone metabolic processGO:0010565660.709
regulation of cellular amine metabolic processGO:0033238200.708
positive regulation of intracellular transportGO:0032388700.703
immune complex clearanceGO:000243420.701
regulation of type iii hypersensitivityGO:000180330.701
lipopolysaccharide mediated signaling pathwayGO:0031663250.699
regulation of endocytosisGO:0030100690.691
single organism cell adhesionGO:00986021560.689
leukocyte degranulationGO:0043299270.684
regulation of t cell differentiationGO:0045580830.681
neutrophil activationGO:004211990.681
serotonin secretion involved in inflammatory responseGO:000244240.680
cellular response to lipidGO:00713961450.680
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.679
granulocyte chemotaxisGO:0071621390.677
positive regulation of apoptotic signaling pathwayGO:2001235950.676
cytokine productionGO:00018163190.675
production of molecular mediator of immune responseGO:00024401030.673
signal transduction in absence of ligandGO:0038034550.665
apical constrictionGO:000338340.663
negative regulation of protein metabolic processGO:00512482820.663
regulation of leukocyte mediated immunityGO:00027031040.663
positive regulation of gamma delta t cell activationGO:004664560.651
forebrain developmentGO:00309003020.650
peptidyl tyrosine phosphorylationGO:00181081430.644
regulation of exocytosisGO:0017157610.642
fc receptor mediated inhibitory signaling pathwayGO:000277410.640
negative regulation of b cell activationGO:0050869270.639
regulation of transferase activityGO:00513382630.630
negative regulation of erk1 and erk2 cascadeGO:0070373210.628
regulation of innate immune responseGO:0045088910.624
regulation of lymphocyte proliferationGO:00506701170.622
regulation of kinase activityGO:00435492490.621
toll like receptor signaling pathwayGO:0002224380.617
chemotaxisGO:00069352470.616
Fly
negative regulation of myeloid leukocyte differentiationGO:0002762200.613
regulation of interleukin 10 productionGO:0032653210.611
small gtpase mediated signal transductionGO:0007264970.609
positive regulation of peptidase activityGO:0010952490.607
regulation of cytokine productionGO:00018172660.601
negative regulation of leukocyte differentiationGO:1902106510.600
defense response to bacteriumGO:00427421190.600
osteoclast differentiationGO:0030316620.600
coagulationGO:0050817780.596
regulation of homotypic cell cell adhesionGO:0034110130.596
regulation of dendritic cell chemotaxisGO:200050810.594
tumor necrosis factor productionGO:0032640500.594
negative regulation of mapk cascadeGO:0043409650.592
cellular lipid metabolic processGO:00442553230.592
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic processGO:004542520.591
dendritic cell apoptotic processGO:009704830.590
antigen processing and presentation of exogenous peptide antigenGO:0002478210.588
erk1 and erk2 cascadeGO:0070371770.580
positive regulation of t cell differentiationGO:0045582520.579
regulation of phosphatidylinositol 3 kinase activityGO:0043551140.574
neutrophil chemotaxisGO:0030593360.573
lymphocyte proliferationGO:00466511640.570
tyrosine phosphorylation of stat proteinGO:0007260230.568
g protein coupled receptor signaling pathwayGO:00071862430.566
inflammatory response to antigenic stimulusGO:0002437300.564
regulation of natural killer cell activationGO:0032814220.563
phospholipid metabolic processGO:0006644870.562
positive regulation of t cell proliferationGO:0042102520.562
regulation of type i hypersensitivityGO:000181040.555
b cell homeostasisGO:0001782340.548
regulation of homeostatic processGO:00328441820.541
positive regulation of acute inflammatory response to antigenic stimulusGO:000286670.539
leukocyte migrationGO:00509001240.538
negative regulation of protein serine threonine kinase activityGO:0071901490.531
positive regulation of podosome assemblyGO:007180330.530
i kappab kinase nf kappab signalingGO:0007249850.529
phagocytosisGO:0006909660.528
negative regulation of protein modification processGO:00314001630.526
cellular ketone metabolic processGO:0042180840.521
positive regulation of alpha beta t cell activationGO:0046635390.512
regulation of vesicle mediated transportGO:00606271390.511
ras protein signal transductionGO:0007265770.511
rho protein signal transductionGO:0007266320.509
response to molecule of bacterial originGO:00022371430.508
platelet activationGO:0030168400.508
regulation of endopeptidase activityGO:0052548890.507
t cell proliferationGO:00420981200.506
cellular zinc ion homeostasisGO:000688290.506
antigen processing and presentation of exogenous peptide antigen via mhc class iGO:004259060.505
regulation of hydrolase activityGO:00513362460.504
second messenger mediated signalingGO:0019932730.503
gamma delta t cell activationGO:0046629130.502
regulation of blood coagulationGO:0030193280.502
cell chemotaxisGO:0060326810.499
regulation of adaptive immune responseGO:0002819900.499
inflammatory responseGO:00069542440.495
cytosolic calcium ion homeostasisGO:0051480700.495
endodermal cell fate specificationGO:000171440.495
regulation of leukocyte degranulationGO:0043300200.492
regulation of interleukin 2 productionGO:0032663280.492
regulation of apoptotic signaling pathwayGO:20012331970.489
membrane organizationGO:00610242450.487
regulation of secretion by cellGO:19035302490.485
regulation of erk1 and erk2 cascadeGO:0070372710.483
fc receptor signaling pathwayGO:003809360.480
cellular metal ion homeostasisGO:00068751510.478
regulation of cell adhesionGO:00301551540.469
Human
cell substrate adhesionGO:00315891300.468
positive regulation of kinase activityGO:00336741550.467
organelle localizationGO:00516401790.466
leukocyte mediated immunityGO:00024431740.466
response to lipopolysaccharideGO:00324961280.465
axonogenesisGO:00074092740.463
Fly
regulation of t cell activationGO:00508631700.459
b cell proliferationGO:0042100530.459
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.458
cd4 positive alpha beta t cell differentiationGO:0043367410.456
divalent metal ion transportGO:00708381720.456
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.455
negative regulation of b cell mediated immunityGO:000271370.455
antigen processing and presentation of peptide antigenGO:0048002290.454
cellular response to cytokine stimulusGO:00713451890.451
olfactory learningGO:000835520.450
homotypic cell cell adhesionGO:0034109280.450
regulation of b cell activationGO:0050864810.447
neutrophil activation involved in immune responseGO:000228380.443
protein localization to nucleusGO:00345041210.443
actin filament organizationGO:00070151130.441
regulation of myeloid leukocyte mediated immunityGO:0002886250.441
protein autophosphorylationGO:0046777610.438
positive regulation of innate immune responseGO:0045089800.438
peptidyl tyrosine modificationGO:00182121450.437
activation of innate immune responseGO:0002218560.436
positive regulation of response to woundingGO:1903036660.436
protein maturationGO:00516041760.431
hemostasisGO:0007599780.430
sequestering of metal ionGO:0051238190.428
negative regulation of phosphorylationGO:00423261660.427
regulation of hemostasisGO:1900046280.425
erythrocyte differentiationGO:0030218880.424
positive regulation of secretionGO:00510471300.423
positive regulation of immunoglobulin mediated immune responseGO:0002891260.403
regulation of podosome assemblyGO:007180130.403
regulation of jak stat cascadeGO:0046425340.401
negative regulation of t cell mediated immunityGO:000271090.400
positive regulation of cell developmentGO:00107202370.398
positive regulation of production of molecular mediator of immune responseGO:0002702450.398
regulation of actin filament lengthGO:0030832450.397
regulation of b cell mediated immunityGO:0002712370.396
calcium mediated signalingGO:0019722460.392
regulation of actin cytoskeleton organizationGO:0032956840.388
antigen processing and presentation of exogenous antigenGO:0019884260.388
granulocyte activationGO:0036230100.386
regulation of leukocyte differentiationGO:19021051590.384
wound healingGO:00420601570.382
lymphocyte homeostasisGO:0002260640.382
negative regulation of insulin receptor signaling pathwayGO:0046627140.379
Mouse
type iia hypersensitivityGO:000179440.378
positive regulation of growth hormone receptor signaling pathwayGO:006039930.374
cellular response to biotic stimulusGO:0071216920.373
exocytosisGO:00068871210.373
regulation of cell shapeGO:0008360390.368
serotonin production involved in inflammatory responseGO:000235140.367
positive regulation of leukocyte apoptotic processGO:2000108210.366
cytoplasmic transportGO:00164822340.365
positive regulation of mast cell activationGO:0033005120.363
positive regulation of mapk cascadeGO:00434101700.361
positive regulation of acute inflammatory responseGO:0002675160.361
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.360
type ii hypersensitivityGO:000244540.359
negative regulation of t helper 1 cell differentiationGO:004562630.358
glycosyl compound catabolic processGO:19016582060.356
negative regulation of cellular component organizationGO:00511291940.355
negative regulation of mast cell proliferationGO:007066710.353
negative regulation of hypersensitivityGO:000288430.351
hematopoietic stem cell migrationGO:003570110.349
Human
regulation of coagulationGO:0050818310.348
negative regulation of apoptotic signaling pathwayGO:20012341040.344
cell type specific apoptotic processGO:00972852680.342
activation of janus kinase activityGO:004297620.341
calcium ion homeostasisGO:00550741270.334
b cell receptor signaling pathwayGO:0050853200.334
regulation of interleukin 6 productionGO:0032675550.332
plasma membrane organizationGO:0007009900.331
antigen processing and presentation of peptide or polysaccharide antigen via mhc class iiGO:0002504170.331
mapk cascadeGO:00001652810.329
negative regulation of phosphorus metabolic processGO:00105631840.328
cellular response to hormone stimulusGO:00328701500.318
Mouse
purine ribonucleotide metabolic processGO:00091502900.316
negative regulation of immune effector processGO:0002698550.316
negative regulation of lymphocyte mediated immunityGO:0002707210.315
regulation of peptidyl tyrosine phosphorylationGO:0050730930.313
response to metal ionGO:0010038470.311
positive regulation of programmed cell deathGO:00430682180.310
actin polymerization or depolymerizationGO:0008154540.309
positive regulation of b cell activationGO:0050871490.308
regulation of ion transportGO:00432692150.307
regulation of dendritic cell cytokine productionGO:000273020.301
type i hypersensitivityGO:001606840.300
positive regulation of t cell mediated cytotoxicityGO:0001916150.300
negative regulation of lymphocyte proliferationGO:0050672450.297
response to alcoholGO:0097305480.296
peptidyl amino acid modificationGO:00181933360.295
regulation of map kinase activityGO:00434051200.293
hypersensitivityGO:0002524100.292
positive regulation of alpha beta t cell differentiationGO:0046638280.291
single organismal cell cell adhesionGO:00163371310.290
cellular response to lipopolysaccharideGO:0071222770.290
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.290
regulation of acute inflammatory responseGO:0002673270.290
regulation of lymphocyte differentiationGO:00456191070.288
jak stat cascadeGO:0007259420.288
learningGO:0007612980.287
positive regulation of humoral immune responseGO:0002922110.285
immunoglobulin mediated immune responseGO:0016064690.285
regulation of protein localization to nucleusGO:1900180600.282
negative regulation of cellular protein metabolic processGO:00322692470.279
positive regulation of map kinase activityGO:0043406840.278
positive regulation of cytosolic calcium ion concentrationGO:0007204650.276
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.274
regulation of cysteine type endopeptidase activityGO:2000116650.274
neuron projection guidanceGO:00974851410.272
Fly
positive regulation of endopeptidase activityGO:0010950430.270
regulation of tumor necrosis factor biosynthetic processGO:0042534100.269
extrinsic apoptotic signaling pathwayGO:00971911260.268
positive regulation of protein kinase activityGO:00458601440.267
regulation of humoral immune response mediated by circulating immunoglobulinGO:0002923100.267
positive regulation of lymphocyte proliferationGO:0050671700.267
positive regulation of type iia hypersensitivityGO:000179840.263
myeloid cell apoptotic processGO:0033028220.261
activation of cysteine type endopeptidase activityGO:0097202270.256
zymogen activationGO:0031638410.255
humoral immune response mediated by circulating immunoglobulinGO:0002455140.255
membrane invaginationGO:0010324170.254
regulation of phospholipase c activityGO:190027430.251
response to growth factorGO:00708481980.248
regulation of protein kinase activityGO:00458592320.247
actin filament bundle assemblyGO:0051017400.246
myeloid cell differentiationGO:00300992330.245
innate immune responseGO:00450871570.245
modulation by virus of host processGO:001905420.240
memoryGO:0007613580.239
protein localization to membraneGO:00726571080.239
positive regulation of reactive oxygen species biosynthetic processGO:190342820.239
cell adhesionGO:00071553290.237
filtration diaphragm assemblyGO:003605810.237
osteoclast developmentGO:003603590.234
guanosine containing compound catabolic processGO:19010691440.233
positive regulation of transferase activityGO:00513471670.232
leukocyte proliferationGO:00706611720.232
positive regulation of jak stat cascadeGO:0046427220.231
negative regulation of antigen receptor mediated signaling pathwayGO:0050858160.229
b cell differentiationGO:0030183780.229
compound eye developmentGO:004874910.228
glycoprotein metabolic processGO:00091001160.225
regulation of wound healingGO:0061041400.224
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.224
negative regulation of alcohol biosynthetic processGO:190293140.223
regulation of rho gtpase activityGO:0032319580.223
positive regulation of endocytosisGO:0045807420.222
negative regulation of type i hypersensitivityGO:000181110.221
response to platelet derived growth factorGO:003611960.221
regulation of b cell apoptotic processGO:0002902130.221
reactive nitrogen species metabolic processGO:200105700.220
cd4 positive alpha beta t cell activationGO:0035710450.219
positive regulation of calcium mediated signalingGO:0050850150.219
regulation of protein transportGO:00512231630.219
cellular response to organonitrogen compoundGO:00714171450.218
Mouse
mast cell apoptotic processGO:003302450.216
positive regulation of leukocyte mediated immunityGO:0002705700.214
platelet aggregationGO:0070527200.214
regulation of phosphatidylinositol 3 kinase signalingGO:0014066300.214
negative regulation of t cell activationGO:0050868650.209
digestive tract developmentGO:00485651900.208
regulation of protein secretionGO:0050708820.207
regulation of myeloid leukocyte differentiationGO:0002761580.207
positive regulation of phospholipase activityGO:001051830.206
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.205
regulation of peptidase activityGO:0052547960.204
tumor necrosis factor biosynthetic processGO:0042533100.204
regulation of cytoskeleton organizationGO:00514931220.202
purine ribonucleoside triphosphate metabolic processGO:00092052200.202
interleukin 10 productionGO:0032613230.201
glucose transportGO:0015758560.201
regulation of secretionGO:00510462740.198
cellular chemical homeostasisGO:00550822150.198
regulation of actin polymerization or depolymerizationGO:0008064450.197
gland developmentGO:00487323300.197
digestive system developmentGO:00551232000.194
negative regulation of lymphocyte apoptotic processGO:0070229240.193
negative regulation of t cell mediated cytotoxicityGO:000191530.193
positive regulation of tyrosine phosphorylation of stat proteinGO:0042531150.193
antigen processing and presentationGO:0019882470.192
parallel actin filament bundle assemblyGO:003004620.191
anatomical structure homeostasisGO:00602491450.190
carbohydrate derivative biosynthetic processGO:19011371830.189
regulation of protein localizationGO:00328802310.188
endocytosisGO:00068971680.187
protein processingGO:00164851630.185
cation homeostasisGO:00550802120.185
regulation of organelle organizationGO:00330432890.185
serotonin secretionGO:000182080.185
cellular response to organic cyclic compoundGO:0071407870.184
regulation of protein complex assemblyGO:0043254830.184
positive regulation of protein localization to nucleusGO:1900182300.182
sensory perceptionGO:00076002450.182
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.182
regulation of establishment of protein localizationGO:00702011810.181
myeloid leukocyte differentiationGO:00025731190.180
ribonucleoside metabolic processGO:00091192450.179
positive regulation of purine nucleotide catabolic processGO:0033123880.177
positive regulation of type i hypersensitivityGO:000181230.177
tumor necrosis factor superfamily cytokine productionGO:0071706510.176
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.176
t helper 17 cell chemotaxisGO:003570510.176
podosome assemblyGO:007180060.176
positive regulation of nervous system developmentGO:00519622210.176
protein secretionGO:00093061110.174
negative regulation of cytokine productionGO:0001818840.174
regulation of calcium ion transport into cytosolGO:0010522310.173
response to organonitrogen compoundGO:00102432460.172
Mouse
regulation of tyrosine phosphorylation of stat proteinGO:0042509200.172
positive regulation of muscle contractionGO:0045933100.172
positive regulation of protein phosphorylationGO:00019342420.172
microtubule based processGO:00070172360.170
response to organic cyclic compoundGO:00140701980.170
regulation of metal ion transportGO:00109591060.169
t cell mediated immunityGO:0002456500.168
positive regulation of interleukin 10 productionGO:0032733120.167
negative regulation of phosphate metabolic processGO:00459361840.167
regulation of mast cell proliferationGO:007066640.166
metal ion homeostasisGO:00550651890.165
negative regulation of molecular functionGO:00440922580.165
intracellular receptor signaling pathwayGO:0030522740.164
negative regulation of leukocyte mediated immunityGO:0002704290.163
protein localization to organelleGO:00333651850.163
acute inflammatory response to antigenic stimulusGO:0002438120.161
granulocyte macrophage colony stimulating factor biosynthetic processGO:004225320.160
lymphocyte mediated immunityGO:00024491390.160
negative regulation of leukocyte apoptotic processGO:2000107310.159
endomembrane system organizationGO:00102561470.159
cytokine secretionGO:0050663720.158
nitrogen compound transportGO:00717052710.158
interleukin 2 mediated signaling pathwayGO:003811020.158
positive regulation of tumor necrosis factor productionGO:0032760300.157
reactive oxygen species metabolic processGO:0072593840.156
gtp catabolic processGO:00061841430.156
cellular response to growth factor stimulusGO:00713631970.154
regulation of myeloid cell apoptotic processGO:0033032190.154
intestinal epithelial cell differentiationGO:0060575140.153
release of sequestered calcium ion into cytosolGO:0051209420.152
calcium ion transport into cytosolGO:0060402480.151

Ptprc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
lupus erythematosusDOID:885700.854
immune system diseaseDOID:291400.854
hypersensitivity reaction diseaseDOID:006005600.854
disease of anatomical entityDOID:700.854
hypersensitivity reaction type ii diseaseDOID:41700.854
systemic lupus erythematosusDOID:907400.619
musculoskeletal system diseaseDOID:1700.619
connective tissue diseaseDOID:6500.619
disease by infectious agentDOID:005011700.341
primary immunodeficiency diseaseDOID:61200.254
severe combined immunodeficiencyDOID:62700.254
combined t cell and b cell immunodeficiencyDOID:62800.254