Mus musculus

49 known processes

Tmc2

transmembrane channel-like gene family 2

(Aliases: CWEA2)

Tmc2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense response to other organismGO:00985421970.421
regulation of defense responseGO:00313472330.219
defense response to bacteriumGO:00427421190.171
regulation of innate immune responseGO:0045088910.119
macromolecule catabolic processGO:00090572810.119
leukocyte differentiationGO:00025213420.095
regulation of inflammatory responseGO:00507271470.093
regulation of multi organism processGO:00439001110.093
cellular amine metabolic processGO:0044106440.090
cellular macromolecule catabolic processGO:00442652060.087
regulation of cellular amine metabolic processGO:0033238200.078
organophosphate biosynthetic processGO:00904071220.076
immune effector processGO:00022523210.076
multicellular organismal signalingGO:0035637910.061
response to acid chemicalGO:00011011110.061
inflammatory responseGO:00069542440.060
organonitrogen compound biosynthetic processGO:19015661920.060
cytokine productionGO:00018163190.059
nucleoside phosphate biosynthetic processGO:1901293790.057
cation transportGO:00068123990.057
positive regulation of cellular amine metabolic processGO:003324050.055
cation transmembrane transportGO:00986552660.054
amine metabolic processGO:0009308450.054
amino acid betaine transportGO:001583830.052
negative regulation of cellular component organizationGO:00511291940.052
negative regulation of cell developmentGO:00107211690.050
positive regulation of defense responseGO:00313491240.050
stem cell developmentGO:00488642190.050
negative regulation of defense responseGO:0031348770.049
regulation of cellular amino acid metabolic processGO:000652150.049
sensory perception of mechanical stimulusGO:00509541070.048
leukocyte migrationGO:00509001240.048
calcium ion transportGO:00068161590.048
transmembrane transportGO:00550854120.047
regulation of system processGO:00440572000.046
regulation of cytokine productionGO:00018172660.046
regulation of protein transportGO:00512231630.046
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.045
positive regulation of innate immune responseGO:0045089800.044
regulation of establishment of protein localizationGO:00702011810.042
positive regulation of protein modification processGO:00314012990.042
detection of chemical stimulus involved in sensory perception of tasteGO:005091230.042
symbiosis encompassing mutualism through parasitismGO:0044403830.042
protein modification by small protein conjugation or removalGO:00706472070.041
cell divisionGO:00513011200.039
protein catabolic processGO:00301632210.039
striated muscle tissue developmentGO:00147062930.038
t cell activationGO:00421102890.038
leukocyte mediated immunityGO:00024431740.038
positive regulation of cell deathGO:00109422240.038
fertilizationGO:00095661270.038
regulation of ion transportGO:00432692150.037
epithelial cell proliferationGO:00506731740.037
regulation of cellular ketone metabolic processGO:0010565660.036
positive regulation of nervous system developmentGO:00519622210.036
stem cell maintenanceGO:00198271300.035
regulation of neuron differentiationGO:00456642810.035
nucleobase containing small molecule metabolic processGO:00550863520.035
protein secretionGO:00093061110.035
positive regulation of cell developmentGO:00107202370.035
positive regulation of transferase activityGO:00513471670.035
embryonic skeletal system developmentGO:00487061200.034
homeostasis of number of cellsGO:00488722100.034
regionalizationGO:00030023370.034
t cell differentiationGO:00302171740.033
cellular response to lipidGO:00713961450.033
regulation of cell activationGO:00508652890.033
sensory perception of soundGO:0007605970.033
regulation of kinase activityGO:00435492490.033
axonogenesisGO:00074092740.033
cellular amino acid metabolic processGO:00065201030.033
regulation of cell divisionGO:0051302760.033
defense response to gram negative bacteriumGO:0050829280.032
innate immune responseGO:00450871570.032
limb developmentGO:00601731660.032
b cell activationGO:00421131610.032
regulation of cellular component biogenesisGO:00440871810.031
regulation of transferase activityGO:00513382630.031
chemotaxisGO:00069352470.031
negative regulation of cytokine productionGO:0001818840.031
nucleoside phosphate metabolic processGO:00067533380.030
response to growth factorGO:00708481980.030
cellular protein catabolic processGO:00442571550.030
skeletal system developmentGO:00015013560.030
regulation of cell migrationGO:00303342190.030
regulation of lymphocyte proliferationGO:00506701170.030
developmental maturationGO:00217001930.029
divalent metal ion transportGO:00708381720.029
regulation of lymphocyte activationGO:00512492400.029
lymphocyte proliferationGO:00466511640.029
negative regulation of neuron differentiationGO:00456651010.029
sequestering of metal ionGO:0051238190.029
lymphocyte differentiationGO:00300982420.029
cell fate commitmentGO:00451652100.029
cellular response to hormone stimulusGO:00328701500.028
protein modification by small protein conjugationGO:00324461870.028
ion transmembrane transportGO:00342203610.028
ameboidal type cell migrationGO:00016671280.028
regulation of organelle organizationGO:00330432890.027
positive regulation of protein phosphorylationGO:00019342420.027
negative regulation of cell activationGO:00508661110.027
protein ubiquitinationGO:00165671710.027
defense response to virusGO:0051607680.027
positive regulation of organelle organizationGO:00106381280.027
regulation of protein localizationGO:00328802310.027
regulation of angiogenesisGO:0045765810.027
regulation of membrane potentialGO:00423911920.026
action potentialGO:0001508780.026
regulation of leukocyte differentiationGO:19021051590.026
ear developmentGO:00435832000.026
neuronal action potentialGO:0019228540.026
epidermis developmentGO:00085441870.026
cell maturationGO:00484691270.026
negative regulation of immune system processGO:00026832090.026
positive regulation of mapk cascadeGO:00434101700.025
regulation of interleukin 6 productionGO:0032675550.025
fat cell differentiationGO:00454441600.025
positive regulation of cell cycle processGO:0090068610.025
muscle contractionGO:00069361010.024
hematopoietic progenitor cell differentiationGO:00022441430.024
cellular ketone metabolic processGO:0042180840.024
proteolysis involved in cellular protein catabolic processGO:00516031470.024
b cell differentiationGO:0030183780.024
muscle tissue developmentGO:00605373080.024
appendage developmentGO:00487361660.024
purine containing compound metabolic processGO:00725213110.024
positive regulation of programmed cell deathGO:00430682180.023
sensory perceptionGO:00076002450.023
regulation of t cell activationGO:00508631700.023
blood circulationGO:00080151950.023
g protein coupled receptor signaling pathwayGO:00071862430.023
modification dependent protein catabolic processGO:00199411330.022
interspecies interaction between organismsGO:0044419830.022
cellular response to cytokine stimulusGO:00713451890.022
defense response to gram positive bacteriumGO:0050830500.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.022
stem cell differentiationGO:00488632680.022
regulation of organ morphogenesisGO:20000271440.021
purine nucleotide biosynthetic processGO:0006164650.021
carbohydrate derivative biosynthetic processGO:19011371830.021
cellular nitrogen compound catabolic processGO:00442702800.021
gland developmentGO:00487323300.020
protein localization to organelleGO:00333651850.020
inner ear receptor cell differentiationGO:0060113610.020
cell fate specificationGO:0001708720.020
purine ribonucleotide metabolic processGO:00091502900.020
divalent inorganic cation transportGO:00725111780.020
negative regulation of nlrp3 inflammasome complex assemblyGO:190022620.020
regulation of purine nucleotide metabolic processGO:19005421690.020
response to lipopolysaccharideGO:00324961280.020
regulation of cell projection organizationGO:00313442060.020
regulation of response to woundingGO:19030341890.019
transmission of nerve impulseGO:0019226760.019
regulation of mapk cascadeGO:00434082480.019
tissue homeostasisGO:00018941150.019
axon guidanceGO:00074111410.019
regulation of tumor necrosis factor productionGO:0032680490.019
regulation of cell motilityGO:20001452360.019
skeletal muscle organ developmentGO:00605381630.019
peptidyl tyrosine modificationGO:00182121450.019
lymphocyte homeostasisGO:0002260640.019
positive regulation of protein kinase activityGO:00458601440.019
cellular protein complex assemblyGO:00436231160.019
positive regulation of epithelial cell proliferationGO:0050679680.019
purine nucleotide metabolic processGO:00061633020.019
regulation of ion transmembrane transportGO:00347651190.019
mapk cascadeGO:00001652810.019
regulation of secretionGO:00510462740.018
positive regulation of cytokine productionGO:00018191740.018
bundle of his developmentGO:000316640.018
morphogenesis of a branching structureGO:00017632030.018
circulatory system processGO:00030131970.018
nuclear transportGO:00511691390.018
regulation of transmembrane transportGO:00347621280.018
limb morphogenesisGO:00351081490.018
midgut developmentGO:000749440.018
neuron migrationGO:00017641220.018
heart contractionGO:0060047930.018
mechanoreceptor differentiationGO:0042490670.018
protein maturationGO:00516041760.018
inorganic ion transmembrane transportGO:00986602340.017
embryonic organ morphogenesisGO:00485622760.017
purine containing compound biosynthetic processGO:0072522700.017
organic hydroxy compound metabolic processGO:19016152030.017
neuron projection guidanceGO:00974851410.017
positive regulation of chemotaxisGO:0050921380.017
dna modificationGO:0006304500.017
cytoplasmic transportGO:00164822340.017
muscle system processGO:00030121410.017
wound healingGO:00420601570.017
viral gene expressionGO:001908030.017
metanephric loop of henle developmentGO:007223640.017
organelle fissionGO:00482851700.017
regulation of cell cycleGO:00517262810.016
regulation of cellular response to stressGO:00801351590.016
immune response regulating signaling pathwayGO:00027641250.016
myeloid cell differentiationGO:00300992330.016
tumor necrosis factor superfamily cytokine productionGO:0071706510.016
ribose phosphate metabolic processGO:00196932910.016
ventral spinal cord interneuron fate commitmentGO:0060579140.016
camera type eye developmentGO:00430102660.016
negative regulation of molecular functionGO:00440922580.016
odontogenesis of dentin containing toothGO:0042475660.016
ubiquitin dependent protein catabolic processGO:00065111290.016
intracellular protein transportGO:00068862040.016
positive regulation of protein transportGO:0051222930.016
regulation of epithelial cell proliferationGO:00506781410.016
diencephalon developmentGO:0021536630.016
ribonucleotide biosynthetic processGO:0009260590.016
endocytosisGO:00068971680.016
memoryGO:0007613580.016
nucleotide biosynthetic processGO:0009165780.016
anatomical structure homeostasisGO:00602491450.016
viral transcriptionGO:001908330.015
reactive oxygen species metabolic processGO:0072593840.015
entry into cell of other organism involved in symbiotic interactionGO:0051806150.015
immune response activating signal transductionGO:00027571160.015
response to oxygen levelsGO:0070482620.015
myeloid leukocyte differentiationGO:00025731190.015
cellular response to growth factor stimulusGO:00713631970.015
antimicrobial peptide biosynthetic processGO:000277720.015
regulation of leukocyte proliferationGO:00706631210.015
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.015
regulation of action potentialGO:009890040.015
cellular amide metabolic processGO:0043603580.015
female gamete generationGO:0007292740.015
innate immune response activating signal transductionGO:0002758500.015
negative regulation of inflammatory responseGO:0050728610.015
blood vessel morphogenesisGO:00485142850.015
positive regulation of cell divisionGO:0051781310.014
regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080010.014
apoptotic signaling pathwayGO:00971903060.014
response to molecule of bacterial originGO:00022371430.014
regulation of wnt signaling pathwayGO:00301111230.014
positive regulation of glial cell differentiationGO:0045687210.014
antimicrobial peptide productionGO:000277520.014
rna processingGO:00063961050.014
myelinationGO:0042552740.014
negative regulation of phosphate metabolic processGO:00459361840.014
positive regulation of immune effector processGO:00026991070.014
response to organonitrogen compoundGO:00102432460.014
production of molecular mediator of immune responseGO:00024401030.014
spinal cord developmentGO:0021510810.014
interleukin 6 productionGO:0032635580.014
regulation of protein complex assemblyGO:0043254830.014
tumor necrosis factor productionGO:0032640500.014
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressureGO:000198810.014
proteasomal protein catabolic processGO:0010498980.014
axon ensheathmentGO:0008366760.014
carbohydrate transportGO:0008643620.014
regulation of protein kinase activityGO:00458592320.014
angiogenesisGO:00015252010.014
regulation of body fluid levelsGO:00508781620.014
epithelial tube morphogenesisGO:00605623030.014
odontogenesisGO:0042476780.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
regulation of nlrp3 inflammasome complex assemblyGO:190022540.013
activation of transmembrane receptor protein tyrosine kinase activityGO:000717130.013
positive regulation of viral entry into host cellGO:004659830.013
response to extracellular stimulusGO:00099911270.013
protein import into nucleusGO:0006606950.013
sensory organ morphogenesisGO:00905962420.013
positive regulation of kinase activityGO:00336741550.013
digestive tract developmentGO:00485651900.013
negative regulation of nervous system developmentGO:00519611560.013
regulation of b cell activationGO:0050864810.013
mesodermal cell migrationGO:000807840.013
modification dependent macromolecule catabolic processGO:00436321330.013
oligodendrocyte differentiationGO:0048709530.013
membrane organizationGO:00610242450.013
b cell activation involved in immune responseGO:0002312500.013
ensheathment of neuronsGO:0007272760.013
regulation of t cell differentiationGO:0045580830.013
wnt signaling pathwayGO:00160551880.013
placenta developmentGO:00018901400.013
regulation of muscle tissue developmentGO:1901861970.013
regulation of nucleotide metabolic processGO:00061401690.013
morphogenesis of a branching epitheliumGO:00611381930.013
development of primary male sexual characteristicsGO:0046546880.013
regulation of saliva secretionGO:004687720.013
sequestering of calcium ionGO:0051208180.013
leukocyte proliferationGO:00706611720.013
respiratory gaseous exchangeGO:0007585430.013
regulation of chemotaxisGO:0050920530.013
rhythmic processGO:00485111740.013
stem cell proliferationGO:00720891170.013
paramesonephric duct developmentGO:006120530.013
male sex differentiationGO:00466611090.013
posttranscriptional regulation of gene expressionGO:00106081550.013
astrocyte fate commitmentGO:006001840.013
single fertilizationGO:0007338820.013
sodium ion transportGO:0006814730.013
regulation of protein serine threonine kinase activityGO:00719001570.012
mitotic cell cycle processGO:19030471590.012
lymphocyte activation involved in immune responseGO:0002285930.012
limbic system developmentGO:0021761720.012
negative regulation of immune effector processGO:0002698550.012
cell activation involved in immune responseGO:00022631260.012
positive regulation of nuclear divisionGO:0051785270.012
regulation of vasculature developmentGO:1901342880.012
chromatin organizationGO:00063252060.012
detection of external stimulusGO:0009581610.012
protein importGO:00170381010.012
germ cell developmentGO:00072811850.012
cytokine metabolic processGO:0042107710.012
glycosyl compound metabolic processGO:19016572460.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
lateral inhibitionGO:004633110.012
negative regulation of phosphorus metabolic processGO:00105631840.012
positive regulation of atpase activityGO:003278130.012
skin developmentGO:00435882200.012
engulfment of apoptotic cellGO:004365230.012
nucleotide metabolic processGO:00091173320.012
forebrain developmentGO:00309003020.012
regulation of antimicrobial humoral responseGO:000275930.012
cyclic nucleotide biosynthetic processGO:0009190440.012
regulation of muscle system processGO:0090257800.012
negative regulation of viral transcriptionGO:003289730.012
adaptive immune responseGO:00022501550.012
nuclear divisionGO:00002801580.012
positive regulation of dopamine secretionGO:003360320.012
purine containing compound catabolic processGO:00725232130.012
nucleoside triphosphate catabolic processGO:00091432050.012
regulation of neural precursor cell proliferationGO:2000177700.012
regulation of acetylcholine secretion neurotransmissionGO:001405620.012
entry into host cellGO:0030260150.011
negative regulation of multi organism processGO:0043901680.011
positive regulation of cellular amino acid metabolic processGO:004576430.011
regulation of cellular catabolic processGO:00313292420.011
regulation of myeloid leukocyte differentiationGO:0002761580.011
activation of adenylate cyclase activityGO:000719040.011
positive regulation of nucleotide metabolic processGO:00459811140.011
ribonucleotide metabolic processGO:00092592910.011
regulation of t cell proliferationGO:0042129920.011
synaptic transmission involved in micturitionGO:006008430.011
detection of stimulus involved in sensory perceptionGO:0050906440.011
negative regulation of cell proliferationGO:00082852960.011
regulation of cell cycle processGO:00105641600.011
response to peptideGO:19016521360.011
positive regulation of apoptotic processGO:00430652170.011
regulation of cytokine secretionGO:0050707610.011
heterocycle catabolic processGO:00467002800.011
compound eye developmentGO:004874910.011
striated muscle cell developmentGO:00550021250.011
purine nucleoside metabolic processGO:00422782410.011
regulation of hydrolase activityGO:00513362460.011
locomotory behaviorGO:00076261950.011
positive regulation of viral genome replicationGO:004507020.011
positive regulation of cell activationGO:00508671580.011
detection of abiotic stimulusGO:0009582600.011
mesenchyme developmentGO:00604851520.011
asymmetric stem cell divisionGO:009872230.011
negative regulation of hydrolase activityGO:0051346710.011
multi multicellular organism processGO:00447061090.011
visceral motor neuron differentiationGO:002152430.011
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.011
regulation of circadian sleep wake cycleGO:004274930.011
synapse organizationGO:00508081250.011
protein processingGO:00164851630.011
body morphogenesisGO:0010171450.011
retina development in camera type eyeGO:00600411190.011
gonad developmentGO:00084061410.011
small gtpase mediated signal transductionGO:0007264970.011
activation of immune responseGO:00022531380.011
telencephalon developmentGO:00215371860.011
neural tube formationGO:00018411080.011
mitotic cell cycleGO:00002781950.011
heart morphogenesisGO:00030071780.011
t cell differentiation in thymusGO:0033077770.011
regulation of viral transcriptionGO:004678230.010
dendrite developmentGO:00163581150.010
regulation of interleukin 8 productionGO:003267730.010
positive regulation of stem cell proliferationGO:2000648590.010
response to decreased oxygen levelsGO:0036293590.010
metencephalon developmentGO:0022037890.010
regulation of actin filament based processGO:0032970990.010
developmental growth involved in morphogenesisGO:00605601380.010
central nervous system projection neuron axonogenesisGO:0021952210.010
negative regulation of action potentialGO:004575910.010
positive regulation of cell motilityGO:20001471160.010
regulation of nucleotide catabolic processGO:00308111220.010
positive regulation of cell cycleGO:0045787920.010
regulation of apoptotic signaling pathwayGO:20012331970.010
biomineral tissue developmentGO:0031214640.010
pattern recognition receptor signaling pathwayGO:0002221470.010
specification of organ identityGO:0010092300.010
positive regulation of interleukin 12 productionGO:0032735210.010
regulation of protein modification by small protein conjugation or removalGO:1903320570.010
protein localization to nucleusGO:00345041210.010
conditioned taste aversionGO:000166140.010
negative regulation of leukocyte mediated immunityGO:0002704290.010
mesenchymal cell proliferation involved in ureter developmentGO:007219840.010

Tmc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
gastrointestinal system diseaseDOID:7700.024
disease of anatomical entityDOID:700.024
disease of cellular proliferationDOID:1456600.022
connective tissue diseaseDOID:6500.017
bone diseaseDOID:008000100.017
musculoskeletal system diseaseDOID:1700.017
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012
nervous system diseaseDOID:86300.012
cancerDOID:16200.011
organ system cancerDOID:005068600.011