Mus musculus

142 known processes

Sh2d1b2

SH2 domain protein 1B2

(Aliases: Ert,EAT-2B,Sh2d1c,Eat2b)

Sh2d1b2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular amine metabolic processGO:0033238200.120
cytokine productionGO:00018163190.107
amine metabolic processGO:0009308450.107
regulation of secretionGO:00510462740.089
t cell activationGO:00421102890.088
positive regulation of cellular amine metabolic processGO:003324050.075
cellular amino acid metabolic processGO:00065201030.074
cation transportGO:00068123990.068
sensory perceptionGO:00076002450.067
positive regulation of secretionGO:00510471300.062
leukocyte activation involved in immune responseGO:00023661260.062
Mouse
cellular amine metabolic processGO:0044106440.061
regulation of leukocyte mediated immunityGO:00027031040.060
cellular response to biotic stimulusGO:0071216920.052
anion transportGO:00068201770.051
innate immune responseGO:00450871570.049
immune effector processGO:00022523210.049
positive regulation of innate immune responseGO:0045089800.048
membrane organizationGO:00610242450.047
detection of fungusGO:001604620.046
cellular response to lipopolysaccharideGO:0071222770.044
macromolecule catabolic processGO:00090572810.044
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.043
reactive oxygen species metabolic processGO:0072593840.043
negative regulation of immune system processGO:00026832090.042
regulation of defense responseGO:00313472330.041
regulation of cytokine productionGO:00018172660.040
regulation of cellular amino acid metabolic processGO:000652150.040
ion transmembrane transportGO:00342203610.040
response to molecule of bacterial originGO:00022371430.039
divalent inorganic cation transportGO:00725111780.039
cell adhesionGO:00071553290.039
regulation of cellular ketone metabolic processGO:0010565660.038
leukocyte differentiationGO:00025213420.037
sequestering of calcium ionGO:0051208180.037
reactive oxygen species biosynthetic processGO:190340980.036
g protein coupled receptor signaling pathwayGO:00071862430.036
regulation of lymphocyte activationGO:00512492400.036
mapk cascadeGO:00001652810.036
regulation of organelle organizationGO:00330432890.035
regulation of cell activationGO:00508652890.035
immune response regulating signaling pathwayGO:00027641250.035
cation transmembrane transportGO:00986552660.035
nucleotide metabolic processGO:00091173320.035
positive regulation of immune effector processGO:00026991070.034
divalent metal ion transportGO:00708381720.033
detection of yeastGO:000187920.033
cellular response to lipidGO:00713961450.033
detection of stimulusGO:0051606840.033
oxidation reduction processGO:00551143420.033
synaptic transmissionGO:00072683290.033
response to molecule of fungal originGO:000223840.033
cell activation involved in immune responseGO:00022631260.033
Mouse
protein secretionGO:00093061110.032
immune response regulating cell surface receptor signaling pathwayGO:0002768800.032
natural killer cell activationGO:0030101440.032
cellular response to molecule of bacterial originGO:0071219830.032
transmembrane transportGO:00550854120.032
regulation of system processGO:00440572000.031
positive regulation of reactive oxygen species biosynthetic processGO:190342820.031
reactive nitrogen species metabolic processGO:200105700.031
epithelial tube morphogenesisGO:00605623030.029
positive regulation of defense responseGO:00313491240.029
regulation of cell cycleGO:00517262810.029
regulation of response to woundingGO:19030341890.029
regulation of secretion by cellGO:19035302490.028
regulation of protein localizationGO:00328802310.028
cell surface pattern recognition receptor signaling pathwayGO:000275220.028
activation of immune responseGO:00022531380.028
protein catabolic processGO:00301632210.028
b cell activationGO:00421131610.028
cellular ketone metabolic processGO:0042180840.028
positive regulation of cellular amino acid metabolic processGO:004576430.028
nucleobase containing small molecule metabolic processGO:00550863520.028
regulation of ion homeostasisGO:2000021640.027
regulation of reactive oxygen species biosynthetic processGO:190342620.027
regulation of ion transportGO:00432692150.027
negative regulation of intracellular signal transductionGO:19025321670.027
apoptotic signaling pathwayGO:00971903060.026
innate immune response activating cell surface receptor signaling pathwayGO:000222040.026
leukocyte mediated cytotoxicityGO:0001909620.026
regulation of innate immune responseGO:0045088910.026
skeletal system developmentGO:00015013560.026
regulation of reactive oxygen species metabolic processGO:2000377400.026
response to acid chemicalGO:00011011110.026
alcohol metabolic processGO:00060661160.025
regulation of protein secretionGO:0050708820.025
response to organonitrogen compoundGO:00102432460.025
inorganic ion transmembrane transportGO:00986602340.024
negative regulation of immune effector processGO:0002698550.024
regulation of wnt signaling pathwayGO:00301111230.024
response to drugGO:0042493750.024
regulation of membrane potentialGO:00423911920.024
cellular response to dna damage stimulusGO:00069742070.023
cellular response to organonitrogen compoundGO:00714171450.023
regulation of establishment of protein localizationGO:00702011810.023
organic hydroxy compound metabolic processGO:19016152030.023
response to organic cyclic compoundGO:00140701980.023
negative regulation of cellular component organizationGO:00511291940.023
ras protein signal transductionGO:0007265770.023
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.023
regulation of apoptotic signaling pathwayGO:20012331970.022
wnt signaling pathwayGO:00160551880.022
dna metabolic processGO:00062593030.022
peptidyl amino acid modificationGO:00181933360.022
response to lipopolysaccharideGO:00324961280.022
positive regulation of protein transportGO:0051222930.022
regulation of actin filament based processGO:0032970990.022
small gtpase mediated signal transductionGO:0007264970.022
sensory perception of chemical stimulusGO:0007606510.021
interferon gamma productionGO:0032609670.021
positive regulation of reactive oxygen species metabolic processGO:2000379110.021
inorganic cation transmembrane transportGO:00986622070.021
regulation of lymphocyte mediated immunityGO:0002706840.021
leukocyte mediated immunityGO:00024431740.021
natural killer cell mediated cytotoxicityGO:0042267290.021
immune response activating signal transductionGO:00027571160.021
regulation of vesicle mediated transportGO:00606271390.021
regulation of mapk cascadeGO:00434082480.021
lymphocyte activation involved in immune responseGO:0002285930.021
circulatory system processGO:00030131970.020
organonitrogen compound catabolic processGO:19015652640.020
cellular response to acid chemicalGO:0071229680.020
positive regulation of leukocyte mediated immunityGO:0002705700.020
cellular lipid metabolic processGO:00442553230.020
negative regulation of cell proliferationGO:00082852960.020
regulation of hydrolase activityGO:00513362460.020
response to growth factorGO:00708481980.020
nucleoside phosphate metabolic processGO:00067533380.020
ribonucleoside metabolic processGO:00091192450.020
hematopoietic progenitor cell differentiationGO:00022441430.020
sequestering of metal ionGO:0051238190.020
lymphocyte proliferationGO:00466511640.020
cation homeostasisGO:00550802120.020
single organism cell adhesionGO:00986021560.020
purine containing compound metabolic processGO:00725213110.020
exocytosisGO:00068871210.019
defense response to bacteriumGO:00427421190.019
regulation of angiotensin levels in bloodGO:000200240.019
carbohydrate derivative catabolic processGO:19011362310.019
carboxylic acid transportGO:00469421000.019
positive regulation of secretion by cellGO:19035321140.019
endocytosisGO:00068971680.019
leukocyte proliferationGO:00706611720.019
negative regulation of phosphorus metabolic processGO:00105631840.018
transmission of nerve impulseGO:0019226760.018
regulation of anatomical structure sizeGO:00900661780.018
negative regulation of protein metabolic processGO:00512482820.018
myeloid cell differentiationGO:00300992330.018
sensory perception of mechanical stimulusGO:00509541070.018
positive regulation of cytokine productionGO:00018191740.018
striated muscle tissue developmentGO:00147062930.018
positive regulation of protein modification processGO:00314012990.018
regulation of cellular catabolic processGO:00313292420.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.018
muscle contractionGO:00069361010.018
protein maturationGO:00516041760.018
cellular divalent inorganic cation homeostasisGO:00725031270.018
purine ribonucleotide metabolic processGO:00091502900.018
inflammatory responseGO:00069542440.018
regulation of blood pressureGO:0008217930.018
organophosphate catabolic processGO:00464342320.018
ribose phosphate metabolic processGO:00196932910.018
positive regulation of lymphocyte mediated immunityGO:0002708620.017
purine nucleotide metabolic processGO:00061633020.017
detection of chemical stimulus involved in sensory perception of tasteGO:005091230.017
positive regulation of cell deathGO:00109422240.017
regulation of b cell activationGO:0050864810.017
transepithelial chloride transportGO:003032140.017
multicellular organismal homeostasisGO:00488711640.017
alpha beta t cell activationGO:0046631910.017
negative regulation of defense responseGO:0031348770.017
ribonucleotide metabolic processGO:00092592910.017
compound eye developmentGO:004874910.017
calcium ion homeostasisGO:00550741270.017
ear developmentGO:00435832000.017
positive regulation of nervous system developmentGO:00519622210.017
calcium ion transportGO:00068161590.017
blood vessel morphogenesisGO:00485142850.017
negative regulation of growthGO:0045926990.017
glycosyl compound metabolic processGO:19016572460.017
organic anion transportGO:00157111370.016
innate immune response activating signal transductionGO:0002758500.016
pattern recognition receptor signaling pathwayGO:0002221470.016
t cell differentiationGO:00302171740.016
cellular alcohol biosynthetic processGO:004410830.016
lymphocyte mediated immunityGO:00024491390.016
positive regulation of apoptotic processGO:00430652170.016
regulation of cellular component biogenesisGO:00440871810.016
activation of innate immune responseGO:0002218560.016
regulation of leukocyte proliferationGO:00706631210.016
blood circulationGO:00080151950.016
cellular calcium ion homeostasisGO:00068741190.016
rho protein signal transductionGO:0007266320.016
organonitrogen compound biosynthetic processGO:19015661920.016
negative regulation of cell activationGO:00508661110.015
negative regulation of cellular amine metabolic processGO:003323910.015
organophosphate biosynthetic processGO:00904071220.015
proteolysis involved in cellular protein catabolic processGO:00516031470.015
regulation of homeostatic processGO:00328441820.015
cellular protein catabolic processGO:00442571550.015
endodermal cell fate specificationGO:000171440.015
action potentialGO:0001508780.015
response to inorganic substanceGO:0010035960.015
protein localization to organelleGO:00333651850.015
positive regulation of interleukin 8 productionGO:003275720.015
morphogenesis of a branching structureGO:00017632030.015
regulation of cell migrationGO:00303342190.015
muscle tissue developmentGO:00605373080.015
regulation of proteolysisGO:00301621640.015
purine ribonucleoside metabolic processGO:00461282410.015
aromatic compound catabolic processGO:00194392860.015
cell killingGO:0001906670.015
placenta developmentGO:00018901400.015
nucleoside phosphate catabolic processGO:19012922220.015
cytoplasmic transportGO:00164822340.015
nuclear divisionGO:00002801580.015
negative regulation of phosphate metabolic processGO:00459361840.015
purine nucleoside triphosphate metabolic processGO:00091442260.015
phagocytosisGO:0006909660.015
cell type specific apoptotic processGO:00972852680.015
regulation of cytokine secretionGO:0050707610.014
adaptive immune responseGO:00022501550.014
digestive tract developmentGO:00485651900.014
anatomical structure homeostasisGO:00602491450.014
regulation of action potentialGO:009890040.014
regulation of cell cycle processGO:00105641600.014
organic cyclic compound catabolic processGO:19013612950.014
purine nucleotide catabolic processGO:00061952110.014
positive regulation of cell killingGO:0031343330.014
camera type eye developmentGO:00430102660.014
single organismal cell cell adhesionGO:00163371310.014
morphogenesis of a branching epitheliumGO:00611381930.014
positive regulation of hydrolase activityGO:00513451480.014
cellular homeostasisGO:00197252400.014
response to radiationGO:00093141650.014
regulation of leukocyte mediated cytotoxicityGO:0001910380.014
regulation of neurotransmitter levelsGO:0001505870.014
b cell differentiationGO:0030183780.014
purine ribonucleoside triphosphate metabolic processGO:00092052200.014
negative regulation of cytokine productionGO:0001818840.014
regulation of lymphocyte proliferationGO:00506701170.014
negative regulation of cell developmentGO:00107211690.014
multicellular organismal signalingGO:0035637910.014
negative regulation of cellular protein metabolic processGO:00322692470.013
alcohol biosynthetic processGO:0046165430.013
negative regulation of molecular functionGO:00440922580.013
positive regulation of protein phosphorylationGO:00019342420.013
actin filament organizationGO:00070151130.013
embryonic placenta developmentGO:0001892980.013
positive regulation of mapk cascadeGO:00434101700.013
negative regulation of secretionGO:0051048610.013
mitotic cell cycle processGO:19030471590.013
cellular alcohol metabolic processGO:004410730.013
cartilage developmentGO:00512161400.013
striated muscle contractionGO:0006941450.013
cellular metal ion homeostasisGO:00068751510.013
cellular macromolecule catabolic processGO:00442652060.013
regulation of transferase activityGO:00513382630.013
positive regulation of programmed cell deathGO:00430682180.013
nitrogen compound transportGO:00717052710.013
regulation of protein catabolic processGO:00421761080.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
stem cell differentiationGO:00488632680.013
positive regulation of cell developmentGO:00107202370.013
nucleoside metabolic processGO:00091162460.013
metal ion homeostasisGO:00550651890.013
vesicle organizationGO:0016050600.013
peptidyl tyrosine phosphorylationGO:00181081430.013
protein modification by small protein conjugationGO:00324461870.013
positive regulation of neuron projection developmentGO:0010976790.013
regulation of cellular response to stressGO:00801351590.013
cellular chemical homeostasisGO:00550822150.013
ossificationGO:00015032160.013
calcium ion transmembrane transportGO:0070588850.013
regulation of interferon gamma productionGO:0032649570.013
i kappab kinase nf kappab signalingGO:0007249850.013
cytokine secretionGO:0050663720.013
protein modification by small protein conjugation or removalGO:00706472070.013
modification dependent protein catabolic processGO:00199411330.013
posttranscriptional regulation of gene expressionGO:00106081550.013
regulation of neuron differentiationGO:00456642810.013
axonogenesisGO:00074092740.013
positive regulation of lymphocyte activationGO:00512511400.013
regulation of cytoskeleton organizationGO:00514931220.013
mitotic cell cycleGO:00002781950.013
regulation of interferon beta biosynthetic processGO:004535740.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.012
negative regulation of t cell activationGO:0050868650.012
stimulatory c type lectin receptor signaling pathwayGO:000222320.012
cellular response to organic cyclic compoundGO:0071407870.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
cellular response to molecule of fungal originGO:007122620.012
chemotaxisGO:00069352470.012
protein processingGO:00164851630.012
modification dependent macromolecule catabolic processGO:00436321330.012
divalent inorganic cation homeostasisGO:00725071380.012
regulation of synaptic growth at neuromuscular junctionGO:000858240.012
connective tissue developmentGO:00614481790.012
cellular response to hormone stimulusGO:00328701500.012
detection of external stimulusGO:0009581610.012
lipid transportGO:0006869980.012
myeloid leukocyte activationGO:0002274830.012
negative regulation of lymphocyte activationGO:0051250910.012
humoral immune responseGO:0006959570.012
Mouse
fat cell differentiationGO:00454441600.012
amino acid transportGO:0006865610.012
regulation of cell killingGO:0031341400.012
ribonucleoside triphosphate metabolic processGO:00091992200.012
organelle assemblyGO:00709251770.012
purine ribonucleoside triphosphate catabolic processGO:00092071990.012
regulation of cell projection organizationGO:00313442060.012
nucleoside triphosphate metabolic processGO:00091412300.012
regulation of endocytosisGO:0030100690.012
lymphocyte differentiationGO:00300982420.012
cellular nitrogen compound catabolic processGO:00442702800.012
appendage developmentGO:00487361660.012
purine nucleoside metabolic processGO:00422782410.012
regulation of interleukin 8 productionGO:003267730.012
membrane fusionGO:0061025380.012
neurotransmitter transportGO:0006836760.012
cellular response to growth factor stimulusGO:00713631970.012
cellular ion homeostasisGO:00068731650.011
nucleotide catabolic processGO:00091662170.011
nucleoside catabolic processGO:00091642060.011
neural tube developmentGO:00219151600.011
homeostasis of number of cellsGO:00488722100.011
monocarboxylic acid metabolic processGO:00327871910.011
positive regulation of interleukin 18 productionGO:003274120.011
cellular response to cytokine stimulusGO:00713451890.011
digestive tract morphogenesisGO:00485461470.011
cellularizationGO:000734910.011
cardiac chamber morphogenesisGO:0003206930.011
positive regulation of endocytosisGO:0045807420.011
regulation of cytoplasmic transportGO:19036491120.011
protein localization to nucleusGO:00345041210.011
glycosyl compound catabolic processGO:19016582060.011
extracellular matrix organizationGO:00301981470.011
purine nucleoside catabolic processGO:00061522050.011
ribonucleoside catabolic processGO:00424542060.011
plasma membrane organizationGO:0007009900.011
negative regulation of wnt signaling pathway involved in heart developmentGO:000330840.011
regulation of neuron projection developmentGO:00109751690.011
detection of abiotic stimulusGO:0009582600.011
regulation of canonical wnt signaling pathwayGO:0060828820.011
germ cell developmentGO:00072811850.011
oocyte constructionGO:000730820.011
erk1 and erk2 cascadeGO:0070371770.011
cofactor metabolic processGO:0051186800.011
synapse organizationGO:00508081250.011
chloride transportGO:0006821320.011
regulation of erk1 and erk2 cascadeGO:0070372710.011
regulation of cell motilityGO:20001452360.011
lipid biosynthetic processGO:00086101790.011
epidermis developmentGO:00085441870.011
regulation of body fluid levelsGO:00508781620.011
maintenance of locationGO:0051235890.011
organelle fissionGO:00482851700.011
meiotic nuclear divisionGO:00071261150.011
forebrain developmentGO:00309003020.011
regulation of actin cytoskeleton organizationGO:0032956840.011
ubiquitin dependent protein catabolic processGO:00065111290.010
tissue homeostasisGO:00018941150.010
regulation of blood circulationGO:1903522930.010
embryonic organ morphogenesisGO:00485622760.010
sulfur compound metabolic processGO:00067901000.010
response to light stimulusGO:00094161350.010
ribonucleotide catabolic processGO:00092612080.010
regulation of protein serine threonine kinase activityGO:00719001570.010
defense response to other organismGO:00985421970.010
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.010
organ growthGO:00352651170.010
positive regulation of protein oligomerizationGO:003246140.010
positive regulation of neuron differentiationGO:00456661410.010
stem cell developmentGO:00488642190.010
purine ribonucleotide catabolic processGO:00091542080.010
cell growthGO:00160491300.010
production of molecular mediator of immune responseGO:00024401030.010
carbohydrate metabolic processGO:00059752300.010
regulation of angiotensin metabolic processGO:006017740.010
hormone secretionGO:00468791280.010
proteasomal protein catabolic processGO:0010498980.010
small molecule biosynthetic processGO:00442831320.010
muscle cell differentiationGO:00426922610.010
heterocycle catabolic processGO:00467002800.010
developmental growth involved in morphogenesisGO:00605601380.010
regulation of cell adhesionGO:00301551540.010
regulation of transmembrane transportGO:00347621280.010
single fertilizationGO:0007338820.010
regulation of t cell proliferationGO:0042129920.010
tissue remodelingGO:00487711020.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.010

Sh2d1b2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.019
nervous system diseaseDOID:86300.019
sensory system diseaseDOID:005015500.014
connective tissue diseaseDOID:6500.013
musculoskeletal system diseaseDOID:1700.013
disease of metabolismDOID:001466700.012
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
eye and adnexa diseaseDOID:149200.011
bone diseaseDOID:008000100.011
inherited metabolic disorderDOID:65500.010