Mus musculus

0 known processes

Pdlim2

PDZ and LIM domain 2

(Aliases: 4732462F18Rik,MGC37634,Slim)

Pdlim2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleotide metabolic processGO:00091173320.080
nucleoside phosphate metabolic processGO:00067533380.077
amine metabolic processGO:0009308450.072
ribonucleoside metabolic processGO:00091192450.072
purine ribonucleoside metabolic processGO:00461282410.070
glycosyl compound metabolic processGO:19016572460.069
actin cytoskeleton organizationGO:00300362200.067
Mouse Fly
ribose phosphate metabolic processGO:00196932910.065
divalent metal ion transportGO:00708381720.060
cellular ketone metabolic processGO:0042180840.059
ribonucleoside triphosphate metabolic processGO:00091992200.059
purine containing compound metabolic processGO:00725213110.058
nucleoside metabolic processGO:00091162460.058
regulation of cellular ketone metabolic processGO:0010565660.057
glycosyl compound catabolic processGO:19016582060.056
cellular chemical homeostasisGO:00550822150.054
purine nucleotide catabolic processGO:00061952110.053
purine nucleoside metabolic processGO:00422782410.052
organic cyclic compound catabolic processGO:19013612950.052
purine nucleotide metabolic processGO:00061633020.052
cation transportGO:00068123990.052
regulation of cellular amine metabolic processGO:0033238200.051
nitrogen compound transportGO:00717052710.048
guanosine containing compound catabolic processGO:19010691440.048
negative regulation of cellular protein metabolic processGO:00322692470.047
regulation of hydrolase activityGO:00513362460.047
purine ribonucleotide catabolic processGO:00091542080.047
regulation of organelle organizationGO:00330432890.047
cellular amine metabolic processGO:0044106440.046
synaptic transmissionGO:00072683290.046
cellular homeostasisGO:00197252400.046
ras protein signal transductionGO:0007265770.044
organophosphate catabolic processGO:00464342320.044
negative regulation of cellular amine metabolic processGO:003323910.044
ribonucleotide catabolic processGO:00092612080.043
aromatic compound catabolic processGO:00194392860.043
purine nucleoside catabolic processGO:00061522050.042
regulation of cellular amino acid metabolic processGO:000652150.042
nucleobase containing small molecule metabolic processGO:00550863520.042
negative regulation of protein metabolic processGO:00512482820.041
regulation of mapk cascadeGO:00434082480.041
nucleoside catabolic processGO:00091642060.041
divalent inorganic cation transportGO:00725111780.041
cellular nitrogen compound catabolic processGO:00442702800.040
organonitrogen compound catabolic processGO:19015652640.040
positive regulation of mapk cascadeGO:00434101700.040
ribonucleotide metabolic processGO:00092592910.040
small gtpase mediated signal transductionGO:0007264970.040
regulation of transferase activityGO:00513382630.039
regulation of cellular component biogenesisGO:00440871810.039
regulation of purine nucleotide metabolic processGO:19005421690.038
mapk cascadeGO:00001652810.038
gtp metabolic processGO:00460391440.038
transmembrane transportGO:00550854120.037
regulation of actin filament based processGO:0032970990.037
oxidation reduction processGO:00551143420.037
cellular protein complex assemblyGO:00436231160.037
cellular amino acid metabolic processGO:00065201030.037
actin filament polymerizationGO:0030041440.037
positive regulation of protein modification processGO:00314012990.037
regulation of protein kinase activityGO:00458592320.037
negative regulation of hydrolase activityGO:0051346710.036
nucleotide catabolic processGO:00091662170.036
endomembrane system organizationGO:00102561470.036
nucleoside triphosphate metabolic processGO:00091412300.036
ribonucleoside catabolic processGO:00424542060.036
nucleoside phosphate catabolic processGO:19012922220.035
guanosine containing compound metabolic processGO:19010681440.035
negative regulation of cellular amino acid metabolic processGO:004576300.035
ribonucleoside triphosphate catabolic processGO:00092031990.035
regulation of nucleoside metabolic processGO:00091181300.035
gtp catabolic processGO:00061841430.035
regulation of kinase activityGO:00435492490.035
negative regulation of phosphorylationGO:00423261660.035
purine ribonucleoside triphosphate metabolic processGO:00092052200.034
ion transmembrane transportGO:00342203610.034
membrane organizationGO:00610242450.034
purine ribonucleotide metabolic processGO:00091502900.034
purine nucleoside triphosphate catabolic processGO:00091462030.033
negative regulation of phosphorus metabolic processGO:00105631840.033
response to organonitrogen compoundGO:00102432460.033
negative regulation of molecular functionGO:00440922580.033
cell substrate adhesionGO:00315891300.032
Fly
cation homeostasisGO:00550802120.032
cellular metal ion homeostasisGO:00068751510.031
apoptotic signaling pathwayGO:00971903060.031
positive regulation of cellular amino acid metabolic processGO:004576430.031
purine ribonucleoside triphosphate catabolic processGO:00092071990.031
carbohydrate derivative catabolic processGO:19011362310.031
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.031
cell adhesionGO:00071553290.031
Fly
negative regulation of cellular component organizationGO:00511291940.030
muscle cell differentiationGO:00426922610.030
Mouse Fly
regulation of nucleotide metabolic processGO:00061401690.030
positive regulation of cellular amine metabolic processGO:003324050.029
regulation of purine nucleotide catabolic processGO:00331211220.029
protein polymerizationGO:0051258570.029
purine nucleoside triphosphate metabolic processGO:00091442260.029
nucleoside triphosphate catabolic processGO:00091432050.029
cellular lipid metabolic processGO:00442553230.029
cellular divalent inorganic cation homeostasisGO:00725031270.029
regulation of cellular catabolic processGO:00313292420.029
purine ribonucleoside catabolic processGO:00461302050.028
regulation of cell cycleGO:00517262810.028
negative regulation of protein phosphorylationGO:00019331260.028
positive regulation of purine nucleotide metabolic processGO:19005441140.028
regulation of cell adhesionGO:00301551540.028
Fly
cation transmembrane transportGO:00986552660.028
peptidyl amino acid modificationGO:00181933360.027
divalent inorganic cation homeostasisGO:00725071380.027
heterocycle catabolic processGO:00467002800.027
g protein coupled receptor signaling pathwayGO:00071862430.027
calcium ion transportGO:00068161590.026
regulation of anatomical structure sizeGO:00900661780.026
cellular ion homeostasisGO:00068731650.025
organonitrogen compound biosynthetic processGO:19015661920.025
sequestering of metal ionGO:0051238190.025
monocarboxylic acid metabolic processGO:00327871910.025
cellular calcium ion homeostasisGO:00068741190.025
muscle tissue developmentGO:00605373080.025
regulation of neuron differentiationGO:00456642810.025
inorganic cation transmembrane transportGO:00986622070.025
metal ion homeostasisGO:00550651890.025
maintenance of locationGO:0051235890.025
purine containing compound catabolic processGO:00725232130.025
macromolecule catabolic processGO:00090572810.024
protein maturationGO:00516041760.024
regulation of proteolysisGO:00301621640.024
inflammatory responseGO:00069542440.024
positive regulation of nucleotide metabolic processGO:00459811140.024
regulation of actin cytoskeleton organizationGO:0032956840.024
positive regulation of gtpase activityGO:0043547850.024
regulation of cell projection organizationGO:00313442060.024
positive regulation of gtp catabolic processGO:0033126850.024
regulation of actin filament polymerizationGO:0030833380.023
positive regulation of nucleotide catabolic processGO:0030813880.023
mitochondrion organizationGO:00070051340.023
negative regulation of protein modification processGO:00314001630.023
regulation of cell activationGO:00508652890.023
regulation of protein processingGO:0070613960.023
transmission of nerve impulseGO:0019226760.023
carbohydrate metabolic processGO:00059752300.022
positive regulation of programmed cell deathGO:00430682180.022
regulation of defense responseGO:00313472330.022
regulation of hormone levelsGO:00108172110.022
rho protein signal transductionGO:0007266320.022
mitotic cell cycleGO:00002781950.022
negative regulation of phosphate metabolic processGO:00459361840.022
actin filament organizationGO:00070151130.022
Mouse
positive regulation of cell deathGO:00109422240.021
positive regulation of protein phosphorylationGO:00019342420.021
response to inorganic substanceGO:0010035960.021
sequestering of calcium ionGO:0051208180.021
actomyosin structure organizationGO:0031032560.021
Mouse Fly
calcium ion homeostasisGO:00550741270.021
inorganic ion transmembrane transportGO:00986602340.021
endocytosisGO:00068971680.021
peptide secretionGO:00027901140.021
regulation of ras gtpase activityGO:0032318880.021
protein localization to membraneGO:00726571080.021
regulation of feeding behaviorGO:006025930.021
carbohydrate derivative biosynthetic processGO:19011371830.020
response to organic cyclic compoundGO:00140701980.020
actin polymerization or depolymerizationGO:0008154540.020
regulation of cell motilityGO:20001452360.020
regulation of intracellular transportGO:00323861590.020
positive regulation of cellular catabolic processGO:00313311480.020
positive regulation of ras gtpase activityGO:0032320650.020
positive regulation of apoptotic processGO:00430652170.020
positive regulation of purine nucleotide catabolic processGO:0033123880.020
cell junction organizationGO:0034330770.020
i kappab kinase nf kappab signalingGO:0007249850.020
negative regulation of peptidase activityGO:0010466460.019
intrinsic apoptotic signaling pathwayGO:00971931320.019
multicellular organismal signalingGO:0035637910.019
regulation of gtp catabolic processGO:00331241130.019
regulation of secretionGO:00510462740.019
regulation of cell migrationGO:00303342190.019
immune effector processGO:00022523210.019
regulation of interleukin 8 productionGO:003267730.019
carbohydrate homeostasisGO:00335001280.019
circulatory system processGO:00030131970.019
regulation of response to woundingGO:19030341890.019
skeletal system developmentGO:00015013560.018
cytokine productionGO:00018163190.018
regulation of membrane potentialGO:00423911920.018
regulation of homeostatic processGO:00328441820.018
response to growth factorGO:00708481980.018
rac protein signal transductionGO:0016601130.018
leukocyte differentiationGO:00025213420.018
negative regulation of transferase activityGO:0051348850.018
fat cell differentiationGO:00454441600.017
glycoprotein metabolic processGO:00091001160.017
regulation of blood circulationGO:1903522930.017
regulation of cytoskeleton organizationGO:00514931220.017
organelle localizationGO:00516401790.017
lipid biosynthetic processGO:00086101790.017
neuronal action potentialGO:0019228540.017
peptide transportGO:00158331330.017
organophosphate biosynthetic processGO:00904071220.017
action potentialGO:0001508780.017
dna metabolic processGO:00062593030.017
regulation of cell cycle processGO:00105641600.017
positive regulation of rho gtpase activityGO:0032321410.017
regulation of ion transportGO:00432692150.017
cell type specific apoptotic processGO:00972852680.017
positive regulation of kinase activityGO:00336741550.017
cell chemotaxisGO:0060326810.017
epithelial cell proliferationGO:00506731740.017
muscle contractionGO:00069361010.017
ossificationGO:00015032160.017
reactive oxygen species metabolic processGO:0072593840.017
small molecule biosynthetic processGO:00442831320.017
posttranscriptional regulation of gene expressionGO:00106081550.017
regulation of lymphocyte activationGO:00512492400.017
regulation of bindingGO:00510981110.017
amide transportGO:00428861380.017
regulation of protein maturationGO:1903317960.017
glucose homeostasisGO:00425931280.017
cell activation involved in immune responseGO:00022631260.017
intracellular protein transportGO:00068862040.017
peptidyl tyrosine modificationGO:00182121450.016
protein modification by small protein conjugation or removalGO:00706472070.016
protein processingGO:00164851630.016
carboxylic acid transportGO:00469421000.016
negative regulation of protein maturationGO:1903318790.016
protein kinase b signalingGO:0043491740.016
response to lipopolysaccharideGO:00324961280.016
plasma membrane organizationGO:0007009900.016
positive regulation of organelle organizationGO:00106381280.016
protein localization to organelleGO:00333651850.016
negative regulation of cell cycleGO:00457861230.016
multicellular organism growthGO:00352641610.016
positive regulation of nervous system developmentGO:00519622210.016
multi multicellular organism processGO:00447061090.016
leukocyte migrationGO:00509001240.016
positive regulation of cell developmentGO:00107202370.016
connective tissue developmentGO:00614481790.016
positive regulation of transferase activityGO:00513471670.016
hormone secretionGO:00468791280.016
response to radiationGO:00093141650.016
response to acid chemicalGO:00011011110.015
cellular macromolecule catabolic processGO:00442652060.015
cellular response to lipidGO:00713961450.015
positive regulation of protein kinase activityGO:00458601440.015
organic acid biosynthetic processGO:0016053860.015
sulfur compound metabolic processGO:00067901000.015
negative regulation of protein processingGO:0010955790.015
response to molecule of bacterial originGO:00022371430.015
glycoprotein biosynthetic processGO:0009101890.015
regulation of cell substrate adhesionGO:0010810730.015
Fly
cytosolic calcium ion transportGO:0060401480.015
skeletal muscle organ developmentGO:00605381630.015
anion transportGO:00068201770.015
positive regulation of cellular component biogenesisGO:0044089940.015
nuclear divisionGO:00002801580.015
positive regulation of cell adhesionGO:0045785800.015
regulation of epithelial cell proliferationGO:00506781410.015
phospholipid metabolic processGO:0006644870.015
developmental growth involved in morphogenesisGO:00605601380.015
sensory perceptionGO:00076002450.015
wound healingGO:00420601570.015
regulation of protein bindingGO:0043393600.015
positive regulation of hydrolase activityGO:00513451480.015
cellular response to acid chemicalGO:0071229680.015
b cell activationGO:00421131610.015
stress activated protein kinase signaling cascadeGO:0031098810.014
interleukin 8 productionGO:003263740.014
negative regulation of organelle organizationGO:0010639900.014
cellular response to dna damage stimulusGO:00069742070.014
male gamete generationGO:00482322850.014
blood circulationGO:00080151950.014
regulation of vesicle mediated transportGO:00606271390.014
proteolysis involved in cellular protein catabolic processGO:00516031470.014
peptide hormone secretionGO:00300721090.014
regulation of nucleotide catabolic processGO:00308111220.014
response to oxygen levelsGO:0070482620.014
cellular protein catabolic processGO:00442571550.014
regulation of cellular component sizeGO:00325351210.014
regulation of cellular response to stressGO:00801351590.014
protein catabolic processGO:00301632210.014
response to light stimulusGO:00094161350.014
organelle fissionGO:00482851700.014
cellular response to hormone stimulusGO:00328701500.014
protein ubiquitinationGO:00165671710.014
regulation of apoptotic signaling pathwayGO:20012331970.014
mitotic cell cycle processGO:19030471590.014
regulation of transmembrane transportGO:00347621280.013
microtubule based processGO:00070172360.013
chemotaxisGO:00069352470.013
regulation of inflammatory responseGO:00507271470.013
norepinephrine transportGO:001587420.013
positive regulation of secretionGO:00510471300.013
leukocyte mediated immunityGO:00024431740.013
response to peptideGO:19016521360.013
striated muscle tissue developmentGO:00147062930.013
negative regulation of phagocytosisGO:005076540.013
regulation of mitotic cell cycleGO:00073461260.013
regulation of angiogenesisGO:0045765810.013
calcium ion transport into cytosolGO:0060402480.013
urogenital system developmentGO:00016552610.013
activation of adenylate cyclase activityGO:000719040.013
leukocyte activation involved in immune responseGO:00023661260.013
lamellipodium organizationGO:0097581290.013
positive regulation of cell activationGO:00508671580.013
myeloid leukocyte activationGO:0002274830.013
regulation of ras protein signal transductionGO:00465781140.013
positive regulation of nucleoside metabolic processGO:0045979910.013
regulation of muscle tissue developmentGO:1901861970.013
compound eye developmentGO:004874910.013
regulation of protein serine threonine kinase activityGO:00719001570.013
respiratory system developmentGO:00605411900.013
t cell activationGO:00421102890.013
organic hydroxy compound transportGO:0015850930.013
response to insulinGO:00328681000.013
monocarboxylic acid biosynthetic processGO:0072330610.013
cellular component assembly involved in morphogenesisGO:00109271390.013
Mouse Fly
dephosphorylationGO:00163111290.013
epithelial cell developmentGO:00020641590.012
cytoplasmic transportGO:00164822340.012
single organism cell adhesionGO:00986021560.012
skin developmentGO:00435882200.012
cellular response to organonitrogen compoundGO:00714171450.012
activation of immune responseGO:00022531380.012
hematopoietic progenitor cell differentiationGO:00022441430.012
regulation of protein localizationGO:00328802310.012
reactive nitrogen species metabolic processGO:200105700.012
neuron deathGO:00709971540.012
establishment of protein localization to membraneGO:0090150540.012
stem cell differentiationGO:00488632680.012
circadian rhythmGO:00076231140.012
positive regulation of protein serine threonine kinase activityGO:00719021060.012
lateral inhibitionGO:004633110.012
peptidyl serine modificationGO:0018209830.012
angiogenesisGO:00015252010.012
negative regulation of proteolysisGO:0045861740.012
type b pancreatic cell proliferationGO:0044342100.012
nucleoside phosphate biosynthetic processGO:1901293790.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
regulation of protein kinase b signalingGO:0051896560.012
morphogenesis of a branching structureGO:00017632030.012
chromatin organizationGO:00063252060.012
peptidyl tyrosine phosphorylationGO:00181081430.012
leukocyte proliferationGO:00706611720.012
regulation of neuron apoptotic processGO:00435231220.012
regulation of cytoplasmic transportGO:19036491120.012
cellular response to growth factor stimulusGO:00713631970.012
immune response activating signal transductionGO:00027571160.012
cognitionGO:00508901490.012
positive regulation of cell projection organizationGO:0031346950.012
myosin filament organizationGO:003103330.012
regulation of reactive oxygen species biosynthetic processGO:190342620.012
lymphocyte proliferationGO:00466511640.012
ensheathment of neuronsGO:0007272760.011
cellular response to cadmium ionGO:007127630.011
regulation of vasculature developmentGO:1901342880.011
lymphocyte mediated immunityGO:00024491390.011
lipid catabolic processGO:0016042690.011
modification dependent macromolecule catabolic processGO:00436321330.011
response to nutrient levelsGO:00316671090.011
mesodermal cell migrationGO:000807840.011
regulation of cell morphogenesis involved in differentiationGO:00107691510.011
protein localization to plasma membraneGO:0072659570.011
glucose metabolic processGO:0006006920.011
organic hydroxy compound metabolic processGO:19016152030.011
chromatin modificationGO:00165681870.011
regulation of neuron projection developmentGO:00109751690.011
cellular response to inorganic substanceGO:0071241370.011
microtubule cytoskeleton organizationGO:00002261570.011
mitochondrion distributionGO:004831140.011
response to extracellular stimulusGO:00099911270.011
myelinationGO:0042552740.011
calcium ion transmembrane transportGO:0070588850.011
tube formationGO:00351481400.011
retrograde transport endosome to golgiGO:004214720.011
myeloid cell differentiationGO:00300992330.011
cell junction maintenanceGO:003433140.011
negative regulation of cell proliferationGO:00082852960.011
organic anion transportGO:00157111370.011
regulation of cell projection assemblyGO:0060491380.011
carboxylic acid biosynthetic processGO:0046394860.011
regulation of secretion by cellGO:19035302490.011
response to peptide hormoneGO:00434341270.011
protein modification by small protein conjugationGO:00324461870.011
innate immune responseGO:00450871570.011
negative regulation of kinase activityGO:0033673810.011
neuron apoptotic processGO:00514021420.011
regulation of actin polymerization or depolymerizationGO:0008064450.011
regulation of lipid metabolic processGO:00192161180.011
regulation of metal ion transportGO:00109591060.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
regulation of t cell activationGO:00508631700.011
regulation of protein complex assemblyGO:0043254830.011
regulation of intracellular protein transportGO:0033157820.011
monosaccharide metabolic processGO:00059961060.011
histone modificationGO:00165701590.011
sulfur compound biosynthetic processGO:0044272370.011
regulation of neuron deathGO:19012141340.011
maintenance of apical basal cell polarityGO:003509030.011
regulation of norepinephrine secretionGO:001406120.011
anatomical structure homeostasisGO:00602491450.011
lipid localizationGO:00108761260.011
cytokinetic processGO:003250620.011
striated muscle contractionGO:0006941450.011
myosin filament assemblyGO:003103420.011
regulation of endocytosisGO:0030100690.011
response to oxidative stressGO:00069791230.011
respiratory tube developmentGO:00303231670.010
anion transmembrane transportGO:0098656710.010
positive regulation of cell motilityGO:20001471160.010
locomotory behaviorGO:00076261950.010
detection of external stimulusGO:0009581610.010
positive regulation of growthGO:00459271040.010
regulation of establishment of protein localizationGO:00702011810.010
organic acid transportGO:00158491010.010
erk1 and erk2 cascadeGO:0070371770.010
regulation of system processGO:00440572000.010
hemostasisGO:0007599780.010
forebrain developmentGO:00309003020.010
cellular carbohydrate metabolic processGO:00442621190.010
positive regulation of neuron differentiationGO:00456661410.010
positive regulation of secretion by cellGO:19035321140.010
mitotic cytokinesisGO:000028140.010
rap protein signal transductionGO:003248630.010
spermatogenesisGO:00072832840.010
asymmetric stem cell divisionGO:009872230.010
gliogenesisGO:00420631410.010
regulation of protein catabolic processGO:00421761080.010
regulation of cytokine productionGO:00018172660.010
positive regulation of lymphocyte activationGO:00512511400.010
protein targetingGO:00066051430.010
ubiquitin dependent protein catabolic processGO:00065111290.010
positive regulation of apoptotic signaling pathwayGO:2001235950.010
adult locomotory behaviorGO:0008344910.010
alcohol metabolic processGO:00060661160.010

Pdlim2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.040
disease of anatomical entityDOID:700.040
sensory system diseaseDOID:005015500.031
immune system diseaseDOID:291400.022
disease of metabolismDOID:001466700.018
retinal diseaseDOID:567900.014
eye diseaseDOID:561400.014
eye and adnexa diseaseDOID:149200.014
retinal degenerationDOID:846600.014
acquired metabolic diseaseDOID:006015800.011