Mus musculus

0 known processes

Pcsk7

proprotein convertase subtilisin/kexin type 7

(Aliases: AA959856,SPC7,PC7)

Pcsk7 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203610.209
transmembrane transportGO:00550854120.129
cation transmembrane transportGO:00986552660.108
cation transportGO:00068123990.106
regulation of cellular ketone metabolic processGO:0010565660.097
cellular ketone metabolic processGO:0042180840.089
membrane organizationGO:00610242450.088
anion transportGO:00068201770.068
inorganic ion transmembrane transportGO:00986602340.065
inorganic cation transmembrane transportGO:00986622070.065
cellular homeostasisGO:00197252400.065
glycoprotein metabolic processGO:00091001160.061
organic acid transportGO:00158491010.061
nitrogen compound transportGO:00717052710.059
cellular amino acid metabolic processGO:00065201030.056
cellular ion homeostasisGO:00068731650.055
negative regulation of cell developmentGO:00107211690.055
cation homeostasisGO:00550802120.053
negative regulation of phosphorus metabolic processGO:00105631840.051
regulation of cellular catabolic processGO:00313292420.051
regulation of cellular amino acid metabolic processGO:000652150.051
regulation of hydrolase activityGO:00513362460.050
positive regulation of protein modification processGO:00314012990.049
cellular lipid metabolic processGO:00442553230.049
purine ribonucleotide catabolic processGO:00091542080.049
negative regulation of protein metabolic processGO:00512482820.048
regulation of cellular amine metabolic processGO:0033238200.047
carbohydrate derivative catabolic processGO:19011362310.045
carbohydrate metabolic processGO:00059752300.043
amine metabolic processGO:0009308450.043
positive regulation of cellular amino acid metabolic processGO:004576430.043
organic anion transportGO:00157111370.043
aromatic compound catabolic processGO:00194392860.042
cellular chemical homeostasisGO:00550822150.042
cellular nitrogen compound catabolic processGO:00442702800.041
negative regulation of phosphorylationGO:00423261660.041
heterocycle catabolic processGO:00467002800.041
positive regulation of cellular amine metabolic processGO:003324050.040
nucleotide catabolic processGO:00091662170.039
mitochondrion organizationGO:00070051340.039
divalent inorganic cation transportGO:00725111780.039
glycosyl compound catabolic processGO:19016582060.038
calcium ion transmembrane transportGO:0070588850.038
carboxylic acid transportGO:00469421000.037
peptidyl amino acid modificationGO:00181933360.037
glycoprotein biosynthetic processGO:0009101890.037
nucleotide metabolic processGO:00091173320.036
endocytosisGO:00068971680.036
positive regulation of apoptotic processGO:00430652170.036
cellular response to hormone stimulusGO:00328701500.036
macromolecule glycosylationGO:0043413550.035
purine nucleotide catabolic processGO:00061952110.035
apoptotic signaling pathwayGO:00971903060.035
carbohydrate derivative biosynthetic processGO:19011371830.035
ras protein signal transductionGO:0007265770.035
regulation of ion transportGO:00432692150.035
negative regulation of nervous system developmentGO:00519611560.035
positive regulation of protein phosphorylationGO:00019342420.035
regulation of mapk cascadeGO:00434082480.034
positive regulation of cell deathGO:00109422240.034
nucleobase containing small molecule metabolic processGO:00550863520.034
metal ion homeostasisGO:00550651890.034
organic cyclic compound catabolic processGO:19013612950.033
protein modification by small protein conjugationGO:00324461870.033
fatty acid metabolic processGO:00066311210.031
cellular metal ion homeostasisGO:00068751510.031
regulation of cytoskeleton organizationGO:00514931220.031
purine nucleoside triphosphate catabolic processGO:00091462030.030
gland developmentGO:00487323300.030
regulation of kinase activityGO:00435492490.030
chromatin modificationGO:00165681870.030
glycosyl compound metabolic processGO:19016572460.030
anion transmembrane transportGO:0098656710.030
very long chain fatty acid catabolic processGO:004276020.030
cytoplasmic transportGO:00164822340.030
regulation of transferase activityGO:00513382630.029
regulation of transmembrane transportGO:00347621280.029
cellular amine metabolic processGO:0044106440.029
organophosphate catabolic processGO:00464342320.029
nucleoside catabolic processGO:00091642060.029
small gtpase mediated signal transductionGO:0007264970.029
regionalizationGO:00030023370.029
translationGO:0006412930.028
modification dependent protein catabolic processGO:00199411330.028
maintenance of locationGO:0051235890.028
lipid transportGO:0006869980.028
ribonucleoside triphosphate catabolic processGO:00092031990.028
regulation of secretionGO:00510462740.027
purine containing compound catabolic processGO:00725232130.027
nucleoside phosphate catabolic processGO:19012922220.027
ribonucleotide catabolic processGO:00092612080.026
protein maturationGO:00516041760.026
Human
purine nucleoside triphosphate metabolic processGO:00091442260.026
divalent inorganic cation homeostasisGO:00725071380.026
ribonucleoside triphosphate metabolic processGO:00091992200.026
purine ribonucleoside triphosphate catabolic processGO:00092071990.025
endomembrane system organizationGO:00102561470.025
regulation of ras protein signal transductionGO:00465781140.025
protein processingGO:00164851630.025
Human
organonitrogen compound catabolic processGO:19015652640.025
regulation of proteolysisGO:00301621640.025
rhythmic processGO:00485111740.025
macromolecule catabolic processGO:00090572810.024
peptide secretionGO:00027901140.024
regulation of organelle organizationGO:00330432890.024
regulation of protein kinase activityGO:00458592320.024
calcium ion transportGO:00068161590.024
protein localization to organelleGO:00333651850.024
positive regulation of kinase activityGO:00336741550.024
positive regulation of innate immune responseGO:0045089800.024
purine ribonucleoside triphosphate metabolic processGO:00092052200.023
regulation of ras gtpase activityGO:0032318880.023
microtubule based processGO:00070172360.023
glycerolipid metabolic processGO:00464861220.023
regulation of ion transmembrane transportGO:00347651190.023
positive regulation of programmed cell deathGO:00430682180.023
regulation of hormone levelsGO:00108172110.023
immune effector processGO:00022523210.023
regulation of cell cycleGO:00517262810.023
negative regulation of molecular functionGO:00440922580.023
regulation of translationGO:0006417710.023
positive regulation of transferase activityGO:00513471670.023
alpha amino acid metabolic processGO:1901605590.023
negative regulation of phosphate metabolic processGO:00459361840.022
forebrain developmentGO:00309003020.022
actin cytoskeleton organizationGO:00300362200.022
ribose phosphate metabolic processGO:00196932910.022
posttranscriptional regulation of gene expressionGO:00106081550.022
mapk cascadeGO:00001652810.022
response to peptideGO:19016521360.022
cellular response to biotic stimulusGO:0071216920.022
cytokine productionGO:00018163190.022
purine nucleoside metabolic processGO:00422782410.022
response to organonitrogen compoundGO:00102432460.022
lipid biosynthetic processGO:00086101790.022
purine nucleoside catabolic processGO:00061522050.022
regulation of organ morphogenesisGO:20000271440.021
purine ribonucleoside metabolic processGO:00461282410.021
regulation of secretion by cellGO:19035302490.021
regulation of establishment of protein localizationGO:00702011810.021
histone modificationGO:00165701590.021
glucose homeostasisGO:00425931280.021
regulation of cell activationGO:00508652890.021
compound eye developmentGO:004874910.021
regulation of nucleoside metabolic processGO:00091181300.021
organelle assemblyGO:00709251770.021
synaptic transmissionGO:00072683290.021
regulation of cellular response to stressGO:00801351590.021
sensory system developmentGO:004888030.021
nucleoside metabolic processGO:00091162460.020
regulation of mitotic cell cycleGO:00073461260.020
nucleoside phosphate metabolic processGO:00067533380.020
divalent metal ion transportGO:00708381720.020
transition metal ion homeostasisGO:0055076540.020
cellular transition metal ion homeostasisGO:0046916320.020
purine ribonucleoside catabolic processGO:00461302050.020
cellular macromolecule catabolic processGO:00442652060.020
positive regulation of organelle organizationGO:00106381280.019
protein glycosylationGO:0006486550.019
insulin secretionGO:0030073890.019
nuclear divisionGO:00002801580.019
regulation of cellular component biogenesisGO:00440871810.019
purine containing compound metabolic processGO:00725213110.019
purine ribonucleotide metabolic processGO:00091502900.019
response to acid chemicalGO:00011011110.019
peptide hormone secretionGO:00300721090.019
monocarboxylic acid metabolic processGO:00327871910.019
negative regulation of cell proliferationGO:00082852960.019
g protein coupled receptor signaling pathwayGO:00071862430.019
protein modification by small protein conjugation or removalGO:00706472070.018
localization within membraneGO:005166840.018
positive regulation of defense responseGO:00313491240.018
cellular response to lipidGO:00713961450.018
ribonucleoside catabolic processGO:00424542060.018
sequestering of calcium ionGO:0051208180.018
proteasomal protein catabolic processGO:0010498980.018
regulation of metal ion transportGO:00109591060.018
negative regulation of intracellular signal transductionGO:19025321670.018
regulation of purine nucleotide catabolic processGO:00331211220.018
regulation of cell migrationGO:00303342190.018
calcium ion homeostasisGO:00550741270.018
cognitionGO:00508901490.017
cellular response to peptideGO:1901653920.017
exocytosisGO:00068871210.017
covalent chromatin modificationGO:00165691630.017
rho protein signal transductionGO:0007266320.017
cell type specific apoptotic processGO:00972852680.017
regulation of apoptotic signaling pathwayGO:20012331970.017
intra golgi vesicle mediated transportGO:000689110.017
sensory perceptionGO:00076002450.017
sequestering of metal ionGO:0051238190.017
nucleoside triphosphate metabolic processGO:00091412300.017
lipid localizationGO:00108761260.017
leukocyte differentiationGO:00025213420.017
ribonucleotide metabolic processGO:00092592910.017
ribonucleoside metabolic processGO:00091192450.017
purine nucleotide metabolic processGO:00061633020.017
negative regulation of cellular component organizationGO:00511291940.017
amide transportGO:00428861380.017
cell adhesionGO:00071553290.017
cellular response to dna damage stimulusGO:00069742070.017
skeletal system developmentGO:00015013560.017
stem cell developmentGO:00488642190.017
defense response to bacteriumGO:00427421190.017
t cell activationGO:00421102890.017
modification dependent macromolecule catabolic processGO:00436321330.017
dna metabolic processGO:00062593030.017
intracellular protein transportGO:00068862040.016
cellular response to lipopolysaccharideGO:0071222770.016
lateral line system developmentGO:004892510.016
multicellular organism growthGO:00352641610.016
positive regulation of cellular catabolic processGO:00313311480.016
negative regulation of protein modification processGO:00314001630.016
negative regulation of immune system processGO:00026832090.016
negative regulation of cellular amine metabolic processGO:003323910.016
organelle fissionGO:00482851700.016
neural tube developmentGO:00219151600.016
defense response to other organismGO:00985421970.016
positive regulation of hydrolase activityGO:00513451480.016
cellular response to peptide hormone stimulusGO:0071375920.016
chromatin organizationGO:00063252060.015
response to nutrient levelsGO:00316671090.015
cellular response to organonitrogen compoundGO:00714171450.015
response to extracellular stimulusGO:00099911270.015
response to peptide hormoneGO:00434341270.015
regulation of cytokine productionGO:00018172660.015
regulation of gtp catabolic processGO:00331241130.015
positive regulation of protein kinase activityGO:00458601440.015
positive regulation of secretionGO:00510471300.015
negative regulation of cellular protein metabolic processGO:00322692470.015
cellular response to cytokine stimulusGO:00713451890.015
regulation of transporter activityGO:0032409570.015
cofactor metabolic processGO:0051186800.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
organic hydroxy compound metabolic processGO:19016152030.015
ubiquitin dependent protein catabolic processGO:00065111290.015
protein localization to nucleusGO:00345041210.015
immune response regulating signaling pathwayGO:00027641250.015
positive regulation of purine nucleotide metabolic processGO:19005441140.015
protein methylationGO:0006479810.015
small molecule biosynthetic processGO:00442831320.015
actin filament organizationGO:00070151130.015
cellularizationGO:000734910.015
engulfment of apoptotic cellGO:004365230.015
regulation of defense responseGO:00313472330.015
regulation of vesicle mediated transportGO:00606271390.014
nucleoside triphosphate catabolic processGO:00091432050.014
regulation of nucleotide metabolic processGO:00061401690.014
leukocyte homeostasisGO:0001776790.014
fatty acid transportGO:0015908280.014
appendage developmentGO:00487361660.014
intracellular receptor signaling pathwayGO:0030522740.014
protein polymerizationGO:0051258570.014
gtp metabolic processGO:00460391440.014
cell divisionGO:00513011200.014
cerebral cortex developmentGO:0021987860.014
peptide transportGO:00158331330.014
regulation of protein localizationGO:00328802310.014
carbohydrate homeostasisGO:00335001280.014
leukocyte proliferationGO:00706611720.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
response to insulinGO:00328681000.014
organonitrogen compound biosynthetic processGO:19015661920.014
regulation of actin cytoskeleton organizationGO:0032956840.014
regulation of cell cycle processGO:00105641600.014
vesicle organizationGO:0016050600.014
regulation of anatomical structure sizeGO:00900661780.014
muscle cell differentiationGO:00426922610.014
cellular response to starvationGO:0009267570.014
pallium developmentGO:00215431200.014
alpha beta t cell differentiationGO:0046632690.014
cellular protein catabolic processGO:00442571550.014
lipid modificationGO:0030258650.014
germ cell developmentGO:00072811850.014
monocarboxylic acid transportGO:0015718440.014
mrna metabolic processGO:0016071840.014
peptidyl serine modificationGO:0018209830.014
fatty acid transmembrane transportGO:190200110.013
negative regulation of triglyceride metabolic processGO:009020940.013
myeloid cell differentiationGO:00300992330.013
striated muscle tissue developmentGO:00147062930.013
regulation of homeostatic processGO:00328441820.013
regulation of nucleotide catabolic processGO:00308111220.013
interspecies interaction between organismsGO:0044419830.013
oxidation reduction processGO:00551143420.013
nucleocytoplasmic transportGO:00069131390.013
negative regulation of multi organism processGO:0043901680.013
glycosylationGO:0070085620.013
epithelial cell proliferationGO:00506731740.013
cellular response to molecule of bacterial originGO:0071219830.013
satellite cell activation involved in skeletal muscle regenerationGO:001490130.013
muscle tissue developmentGO:00605373080.013
positive regulation of gtpase activityGO:0043547850.013
lipid homeostasisGO:0055088630.013
regulation of protein complex assemblyGO:0043254830.013
wnt signaling pathwayGO:00160551880.013
negative regulation of cellular amino acid metabolic processGO:004576300.013
cell maturationGO:00484691270.013
homeostasis of number of cellsGO:00488722100.013
progesterone metabolic processGO:004244840.013
regulation of innate immune responseGO:0045088910.013
positive regulation of nucleotide catabolic processGO:0030813880.013
ribonucleoprotein complex disassemblyGO:003298830.013
alcohol metabolic processGO:00060661160.013
hindbrain developmentGO:00309021280.013
response to molecule of bacterial originGO:00022371430.013
regulation of engulfment of apoptotic cellGO:190107420.013
cofactor transportGO:005118140.012
guanosine containing compound catabolic processGO:19010691440.012
blood circulationGO:00080151950.012
glycerophospholipid metabolic processGO:0006650710.012
regulation of feeding behaviorGO:006025930.012
lipoprotein metabolic processGO:0042157430.012
positive regulation of interleukin 8 productionGO:003275720.012
defecationGO:003042110.012
multi multicellular organism processGO:00447061090.012
protein catabolic processGO:00301632210.012
peptidyl tyrosine phosphorylationGO:00181081430.012
circulatory system processGO:00030131970.012
skeletal system morphogenesisGO:00487052030.012
protein targetingGO:00066051430.012
response to organic cyclic compoundGO:00140701980.012
peptidyl tyrosine modificationGO:00182121450.012
cellular response to acid chemicalGO:0071229680.012
hexose metabolic processGO:0019318980.012
viral gene expressionGO:001908030.012
small molecule catabolic processGO:0044282710.012
appendage morphogenesisGO:00351071490.012
b 1 b cell homeostasisGO:000192240.012
cell fate commitmentGO:00451652100.012
ossificationGO:00015032160.012
positive regulation of secretion by cellGO:19035321140.012
myeloid leukocyte differentiationGO:00025731190.012
negative regulation of cell cycleGO:00457861230.012
protein lipidationGO:0006497280.012
regulation of ion transmembrane transporter activityGO:0032412540.012
hormone secretionGO:00468791280.012
plasma membrane organizationGO:0007009900.012
rna interferenceGO:001624620.012
regulation of map kinase activityGO:00434051200.012
stem cell differentiationGO:00488632680.012
citrate metabolic processGO:000610130.012
retrograde transport endosome to golgiGO:004214720.012
carboxylic acid catabolic processGO:0046395510.011
regulation of peptide transportGO:0090087910.011
innate immune responseGO:00450871570.011
cellular calcium ion homeostasisGO:00068741190.011
axon cargo transportGO:0008088330.011
response to inorganic substanceGO:0010035960.011
regulation of lymphocyte activationGO:00512492400.011
telencephalon developmentGO:00215371860.011
positive regulation of protein transportGO:0051222930.011
multicellular organismal homeostasisGO:00488711640.011
cellular protein complex assemblyGO:00436231160.011
regulation of protein transportGO:00512231630.011
monosaccharide metabolic processGO:00059961060.011
morphogenesis of embryonic epitheliumGO:00163311590.011
regulation of protein processingGO:0070613960.011
autophagic vacuole assemblyGO:0000045130.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
lymphocyte proliferationGO:00466511640.011
response to growth factorGO:00708481980.011
regulation of actin nucleationGO:005112540.011
cellular response to organic cyclic compoundGO:0071407870.011
regulation of rho protein signal transductionGO:0035023710.011
protein oligomerizationGO:0051259670.011
positive regulation of actin nucleationGO:005112730.011
t cell differentiationGO:00302171740.011
tube formationGO:00351481400.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
positive regulation of protein catabolic processGO:0045732600.011
organophosphate biosynthetic processGO:00904071220.011
gtp catabolic processGO:00061841430.011
embryonic organ morphogenesisGO:00485622760.011
neural precursor cell proliferationGO:00613511210.011
zygotic determination of anterior posterior axis embryoGO:000735430.011
nucleotide sugar metabolic processGO:000922540.011
cellular component assembly involved in morphogenesisGO:00109271390.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
regulation of cell morphogenesis involved in differentiationGO:00107691510.011
negative regulation of protein phosphorylationGO:00019331260.011
regulation of multi organism processGO:00439001110.011
regulation of bindingGO:00510981110.011
amino acid transportGO:0006865610.011
negative regulation of organelle organizationGO:0010639900.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
nucleic acid phosphodiester bond hydrolysisGO:0090305490.011
sodium ion transportGO:0006814730.011
positive regulation of mapk cascadeGO:00434101700.011
learning or memoryGO:00076111480.011
membrane lipid biosynthetic processGO:0046467320.011
response to starvationGO:0042594650.010
protein ubiquitinationGO:00165671710.010
negative regulation of cytokine productionGO:0001818840.010
regulation of hormone secretionGO:0046883880.010
metencephalon developmentGO:0022037890.010
digestive tract morphogenesisGO:00485461470.010
eye photoreceptor cell differentiationGO:0001754410.010
extracellular structure organizationGO:00430621480.010
regulation of cellular component sizeGO:00325351210.010
mitotic cytokinesisGO:000028140.010
potassium ion transmembrane transportGO:0071805430.010
skin developmentGO:00435882200.010
positive regulation of cell developmentGO:00107202370.010
regulation of cell projection organizationGO:00313442060.010
positive regulation of cytokine productionGO:00018191740.010
regulation of calcium ion transportGO:0051924690.010
digestive tract developmentGO:00485651900.010
regulation of autophagic vacuole assemblyGO:200078540.010
establishment or maintenance of cytoskeleton polarityGO:003095220.010
response to radiationGO:00093141650.010
locomotory behaviorGO:00076261950.010
inorganic anion transportGO:0015698430.010
response to lipopolysaccharideGO:00324961280.010
viral processGO:0016032410.010
interleukin 8 productionGO:003263740.010
regulation of lymphocyte differentiationGO:00456191070.010
protein autophosphorylationGO:0046777610.010
mitotic cell cycleGO:00002781950.010
myosin filament assemblyGO:003103420.010

Pcsk7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.030
central nervous system diseaseDOID:33100.030
disease of anatomical entityDOID:700.030
immune system diseaseDOID:291400.025
disease of cellular proliferationDOID:1456600.017
brain diseaseDOID:93600.015
hematopoietic system diseaseDOID:7400.014
musculoskeletal system diseaseDOID:1700.013
muscle tissue diseaseDOID:6600.012
muscular diseaseDOID:008000000.012
myopathyDOID:42300.012
neurodegenerative diseaseDOID:128900.011
cancerDOID:16200.011
organ system cancerDOID:005068600.011
inherited metabolic disorderDOID:65500.011
disease of metabolismDOID:001466700.011