IMP: Integrative Multi-species Prediction

Mus musculus

40 known processes

Fcer2a

Fc receptor, IgE, low affinity II, alpha polypeptide

(Aliases: CD23,Ly-42,Fce2,Fcer2)

Entrez: 14128
Ensembl: ENSMUSG00000005540
UniProtKB: P20693
UniProtKB: Q8VH32
UniProtKB: Q8VH33

Process Predictions
Disease Predictions

Fcer2a biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
leukocyte differentiation	GO:0002521	342	0.815
lymphocyte differentiation	GO:0030098	242	0.757
immune response activating cell surface receptor signaling pathway	GO:0002429	72	0.678
hematopoietic stem cell migration	GO:0035701	1	0.645
leukocyte activation involved in immune response	GO:0002366	126	0.602
t cell differentiation	GO:0030217	174	0.598
negative regulation of immune system process	GO:0002683	209	0.594	Mouse
immune response regulating cell surface receptor signaling pathway	GO:0002768	80	0.594
cytokine production	GO:0001816	319	0.572	Mouse
activation of immune response	GO:0002253	138	0.543
regulation of cell activation	GO:0050865	289	0.542	Mouse
positive regulation of lymphocyte activation	GO:0051251	140	0.522
positive regulation of t cell activation	GO:0050870	101	0.519
cellular homeostasis	GO:0019725	240	0.506	Mouse
inflammatory response	GO:0006954	244	0.471
regulation of cellular ketone metabolic process	GO:0010565	66	0.456
cation homeostasis	GO:0055080	212	0.452	Mouse
helper t cell chemotaxis	GO:0035704	1	0.451
cytosolic calcium ion homeostasis	GO:0051480	70	0.449	Mouse
regulation of response to wounding	GO:1903034	189	0.449
immune effector process	GO:0002252	321	0.446
positive regulation of cell activation	GO:0050867	158	0.443
positive regulation of cytokine production	GO:0001819	174	0.441	Mouse
positive regulation of immunological synapse formation	GO:2000522	1	0.436
regulation of lymphocyte activation	GO:0051249	240	0.433	Mouse
myeloid leukocyte activation	GO:0002274	83	0.427
immune response activating signal transduction	GO:0002757	116	0.427
cytokine biosynthetic process	GO:0042089	68	0.416	Mouse
regulation of cellular amino acid metabolic process	GO:0006521	5	0.415
regulation of cellular amine metabolic process	GO:0033238	20	0.415
eosinophil mediated immunity	GO:0002447	1	0.406
metal ion homeostasis	GO:0055065	189	0.395	Mouse
positive regulation of cell migration	GO:0030335	109	0.389
myeloid cell differentiation	GO:0030099	233	0.384
immune response regulating signaling pathway	GO:0002764	125	0.383
regulation of inflammatory response	GO:0050727	147	0.364
response to molecule of bacterial origin	GO:0002237	143	0.353
regulation of eosinophil degranulation	GO:0043309	1	0.348
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.348
antigen receptor mediated signaling pathway	GO:0050851	64	0.345
cellular amine metabolic process	GO:0044106	44	0.343
cellular amino acid metabolic process	GO:0006520	103	0.317
positive regulation of t cell costimulation	GO:2000525	2	0.315
cellular metal ion homeostasis	GO:0006875	151	0.314	Mouse
multicellular organismal signaling	GO:0035637	91	0.301
cell adhesion	GO:0007155	329	0.289
glial cell differentiation	GO:0010001	131	0.286
regulation of t cell activation	GO:0050863	170	0.276	Mouse
monocyte extravasation	GO:0035696	2	0.275
positive regulation of protein phosphorylation	GO:0001934	242	0.275
regulation of leukocyte proliferation	GO:0070663	121	0.274	Mouse
t cell extravasation	GO:0072683	4	0.268
alpha beta t cell activation	GO:0046631	91	0.268	Mouse
regulation of ion transport	GO:0043269	215	0.262	Mouse
regulation of immunological synapse formation	GO:2000520	2	0.259
cation transport	GO:0006812	399	0.253	Mouse
epithelial tube morphogenesis	GO:0060562	303	0.251
t cell activation	GO:0042110	289	0.248	Mouse
positive regulation of mapk cascade	GO:0043410	170	0.246
positive regulation of t cell extravasation	GO:2000409	2	0.246
eosinophil activation	GO:0043307	1	0.242
positive regulation of inflammatory response	GO:0050729	47	0.241
microglial cell activation involved in immune response	GO:0002282	1	0.230
regulation of t cell costimulation	GO:2000523	2	0.228
positive regulation of cellular amine metabolic process	GO:0033240	5	0.228
positive regulation of immune effector process	GO:0002699	107	0.227
cellular ketone metabolic process	GO:0042180	84	0.222
cellular ion homeostasis	GO:0006873	165	0.221	Mouse
divalent inorganic cation transport	GO:0072511	178	0.221	Mouse
gliogenesis	GO:0042063	141	0.215
acute inflammatory response	GO:0002526	41	0.215
leukocyte chemotaxis	GO:0030595	69	0.215
cytokine mediated signaling pathway	GO:0019221	115	0.214
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.213
regulation of membrane potential	GO:0042391	192	0.210
cerebral cortex development	GO:0021987	86	0.204
positive regulation of cell development	GO:0010720	237	0.204
cd8 positive alpha beta t cell extravasation	GO:0035697	3	0.204
regulation of monocyte extravasation	GO:2000437	2	0.201
homeostasis of number of cells	GO:0048872	210	0.198
positive regulation of cytokine biosynthetic process	GO:0042108	40	0.196	Mouse
adaptive immune response	GO:0002250	155	0.193
lymphocyte proliferation	GO:0046651	164	0.192	Mouse
regulation of secretion by cell	GO:1903530	249	0.188	Mouse
release of sequestered calcium ion into cytosol	GO:0051209	42	0.188	Mouse
chemokine mediated signaling pathway	GO:0070098	17	0.186
myeloid cell homeostasis	GO:0002262	114	0.185
wnt signaling pathway	GO:0016055	188	0.185
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.180	Mouse
t cell proliferation	GO:0042098	120	0.177	Mouse
positive regulation of protein modification process	GO:0031401	299	0.176
defense response to other organism	GO:0098542	197	0.175	Mouse
antigen processing and presentation	GO:0019882	47	0.173
negative regulation of eosinophil degranulation	GO:0043310	1	0.172
positive regulation of t cell receptor signaling pathway	GO:0050862	4	0.172
regulation of leukocyte mediated immunity	GO:0002703	104	0.172
regulation of leukocyte differentiation	GO:1902105	159	0.170
positive regulation of monocyte extravasation	GO:2000439	1	0.169
positive regulation of cd8 positive alpha beta t cell extravasation	GO:2000451	2	0.168
muscle tissue development	GO:0060537	308	0.165
regulation of defense response	GO:0031347	233	0.165
immune complex clearance	GO:0002434	2	0.165
t cell differentiation in thymus	GO:0033077	77	0.164
cell type specific apoptotic process	GO:0097285	268	0.163
chemotaxis	GO:0006935	247	0.160
myeloid cell activation involved in immune response	GO:0002275	34	0.160
cytokine secretion	GO:0050663	72	0.159	Mouse
regulation of monocyte chemotaxis	GO:0090025	3	0.158
ensheathment of neurons	GO:0007272	76	0.156
positive regulation of secretion	GO:0051047	130	0.155	Mouse
response to lipopolysaccharide	GO:0032496	128	0.154
regulation of homeostatic process	GO:0032844	182	0.153	Mouse
mature dendritic cell differentiation	GO:0097029	3	0.152
positive regulation of monocyte chemotaxis	GO:0090026	2	0.151
sequestering of metal ion	GO:0051238	19	0.151
t cell receptor signaling pathway	GO:0050852	46	0.150
amine metabolic process	GO:0009308	45	0.150
eosinophil activation involved in immune response	GO:0002278	1	0.149
regulation of cytokine biosynthetic process	GO:0042035	59	0.148	Mouse
b cell proliferation	GO:0042100	53	0.148
positive regulation of immune complex clearance by monocytes and macrophages	GO:0090265	2	0.144
angiogenesis	GO:0001525	201	0.143
regulation of t cell extravasation	GO:2000407	3	0.143
positive regulation of dendritic cell chemotaxis	GO:2000510	1	0.139
negative regulation of cell proliferation	GO:0008285	296	0.138	Mouse
humoral immune response	GO:0006959	57	0.138
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002822	87	0.134
mapk cascade	GO:0000165	281	0.133
cellular chemical homeostasis	GO:0055082	215	0.132	Mouse
regulation of immune complex clearance by monocytes and macrophages	GO:0090264	2	0.132
tumor necrosis factor superfamily cytokine production	GO:0071706	51	0.131	Mouse
positive regulation of nervous system development	GO:0051962	221	0.130
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.130
calcium ion homeostasis	GO:0055074	127	0.129	Mouse
interleukin 12 secretion	GO:0072610	3	0.129
alpha beta t cell proliferation	GO:0046633	21	0.128
regulation of antigen receptor mediated signaling pathway	GO:0050854	29	0.127
regulation of mapk cascade	GO:0043408	248	0.124
b cell differentiation	GO:0030183	78	0.124
positive regulation of protein transport	GO:0051222	93	0.120	Mouse
developmental maturation	GO:0021700	193	0.119
cell activation involved in immune response	GO:0002263	126	0.119
transmission of nerve impulse	GO:0019226	76	0.118
neuronal action potential	GO:0019228	54	0.118
cellular response to biotic stimulus	GO:0071216	92	0.117
regulation of ion homeostasis	GO:2000021	64	0.117	Mouse
positive regulation of response to wounding	GO:1903036	66	0.114
negative regulation of homeostatic process	GO:0032845	71	0.112	Mouse
tumor necrosis factor biosynthetic process	GO:0042533	10	0.112	Mouse
g protein coupled receptor signaling pathway	GO:0007186	243	0.112
regulation of anatomical structure size	GO:0090066	178	0.110
regulation of establishment of protein localization	GO:0070201	181	0.109	Mouse
blood vessel morphogenesis	GO:0048514	285	0.109
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.108	Mouse
regulation of cytokine production	GO:0001817	266	0.108	Mouse
negative regulation of cell activation	GO:0050866	111	0.107	Mouse
leukocyte degranulation	GO:0043299	27	0.107
regulation of cell migration	GO:0030334	219	0.105
negative regulation of protein metabolic process	GO:0051248	282	0.104
regulation of protein transport	GO:0051223	163	0.104	Mouse
morphogenesis of a branching epithelium	GO:0061138	193	0.103
b cell activation	GO:0042113	161	0.102
innate immune response	GO:0045087	157	0.102	Mouse
regulation of innate immune response	GO:0045088	91	0.100
regulation of t cell differentiation	GO:0045580	83	0.100
eosinophil degranulation	GO:0043308	1	0.099
monocarboxylic acid metabolic process	GO:0032787	191	0.098
glycoprotein biosynthetic process	GO:0009101	89	0.097
b cell receptor signaling pathway	GO:0050853	20	0.097
stem cell development	GO:0048864	219	0.097
immune complex clearance by monocytes and macrophages	GO:0002436	2	0.095
single organism nuclear import	GO:1902593	95	0.095
regulation of cell motility	GO:2000145	236	0.094
cellular extravasation	GO:0045123	17	0.094
regulation of tumor necrosis factor production	GO:0032680	49	0.094	Mouse
cellular calcium ion homeostasis	GO:0006874	119	0.092	Mouse
regulation of protein localization	GO:0032880	231	0.092	Mouse
regulation of body fluid levels	GO:0050878	162	0.091
divalent inorganic cation homeostasis	GO:0072507	138	0.090	Mouse
protein localization to nucleus	GO:0034504	121	0.090
sequestering of calcium ion	GO:0051208	18	0.089
forebrain development	GO:0030900	302	0.089
axonogenesis	GO:0007409	274	0.088
oligodendrocyte differentiation	GO:0048709	53	0.087
granulocyte activation	GO:0036230	10	0.087
positive regulation of kinase activity	GO:0033674	155	0.086
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation	GO:2000526	1	0.086
regulation of interleukin 2 production	GO:0032663	28	0.085
interferon gamma production	GO:0032609	67	0.085
skin development	GO:0043588	220	0.085
b cell mediated immunity	GO:0019724	71	0.084
positive regulation of hematopoietic stem cell migration	GO:2000473	1	0.084
regulation of adaptive immune response	GO:0002819	90	0.083
cellular response to lipopolysaccharide	GO:0071222	77	0.082
action potential	GO:0001508	78	0.082
positive regulation of map kinase activity	GO:0043406	84	0.082
lymphocyte mediated immunity	GO:0002449	139	0.082
regulation of cellular response to stress	GO:0080135	159	0.081
negative regulation of macrophage apoptotic process	GO:2000110	3	0.081
regulation of cd8 positive alpha beta t cell extravasation	GO:2000449	3	0.080
glycoprotein metabolic process	GO:0009100	116	0.080
regulation of protein serine threonine kinase activity	GO:0071900	157	0.080
positive regulation of cytokine secretion	GO:0050715	41	0.079	Mouse
gland development	GO:0048732	330	0.079
positive regulation of defense response	GO:0031349	124	0.078
myeloid leukocyte differentiation	GO:0002573	119	0.078
rho protein signal transduction	GO:0007266	32	0.076
positive regulation of leukocyte mediated immunity	GO:0002705	70	0.076
thymic t cell selection	GO:0045061	22	0.076
cytokine metabolic process	GO:0042107	71	0.076	Mouse
regulation of lymphocyte proliferation	GO:0050670	117	0.075	Mouse
erythrocyte differentiation	GO:0030218	88	0.075
stem cell differentiation	GO:0048863	268	0.075
regulation of angiogenesis	GO:0045765	81	0.074
positive regulation of endothelial cell proliferation	GO:0001938	17	0.074
regulation of b cell mediated immunity	GO:0002712	37	0.074
cell chemotaxis	GO:0060326	81	0.074
morphogenesis of a branching structure	GO:0001763	203	0.073
regulation of hematopoietic stem cell migration	GO:2000471	1	0.073
regulation of leukocyte apoptotic process	GO:2000106	56	0.073
cognition	GO:0050890	149	0.072
regulation of endocytosis	GO:0030100	69	0.072	Mouse
positive regulation of leukocyte proliferation	GO:0070665	73	0.072
regulation of dendritic cell chemotaxis	GO:2000508	1	0.072
regulation of phospholipase c activity	GO:1900274	3	0.072
calcium ion transport	GO:0006816	159	0.072	Mouse
regulation of stress activated mapk cascade	GO:0032872	69	0.072
t helper 17 cell chemotaxis	GO:0035705	1	0.071
positive regulation of cell motility	GO:2000147	116	0.071
calcium ion transport into cytosol	GO:0060402	48	0.070	Mouse
defense response to virus	GO:0051607	68	0.070
cellular response to cytokine stimulus	GO:0071345	189	0.070
exocytosis	GO:0006887	121	0.070
activation of mapk activity	GO:0000187	59	0.069
inflammatory response to antigenic stimulus	GO:0002437	30	0.069
regulation of transmembrane transport	GO:0034762	128	0.069
membrane organization	GO:0061024	245	0.069
myeloid leukocyte migration	GO:0097529	57	0.068
carbohydrate derivative biosynthetic process	GO:1901137	183	0.067
t cell selection	GO:0045058	34	0.067
regulation of inflammatory response to antigenic stimulus	GO:0002861	21	0.066
regulation of lymphocyte differentiation	GO:0045619	107	0.066
regulation of vesicle mediated transport	GO:0060627	139	0.066	Mouse
neuron migration	GO:0001764	122	0.066
myeloid leukocyte mediated immunity	GO:0002444	42	0.066
regulation of muscle tissue development	GO:1901861	97	0.066
positive regulation of adaptive immune response	GO:0002821	61	0.065
regulation of intracellular transport	GO:0032386	159	0.064	Mouse
telencephalon development	GO:0021537	186	0.063
myelination	GO:0042552	74	0.063
cellular response to growth factor stimulus	GO:0071363	197	0.063
maintenance of location	GO:0051235	89	0.062
muscle cell differentiation	GO:0042692	261	0.062
lymphocyte activation involved in immune response	GO:0002285	93	0.061
ameboidal type cell migration	GO:0001667	128	0.060
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.060
cellular response to molecule of bacterial origin	GO:0071219	83	0.060
positive regulation of intracellular transport	GO:0032388	70	0.060	Mouse
positive regulation of tumor necrosis factor production	GO:0032760	30	0.060	Mouse
regulation of map kinase activity	GO:0043405	120	0.060
regulation of cytokine secretion	GO:0050707	61	0.059	Mouse
production of molecular mediator of immune response	GO:0002440	103	0.059
positive regulation of protein secretion	GO:0050714	52	0.059	Mouse
extrinsic apoptotic signaling pathway	GO:0097191	126	0.058
regulation of antigen processing and presentation	GO:0002577	10	0.057
regulation of myeloid cell differentiation	GO:0045637	96	0.057
t helper 1 type immune response	GO:0042088	25	0.057
positive regulation of tumor necrosis factor biosynthetic process	GO:0042535	8	0.056	Mouse
regulation of tumor necrosis factor biosynthetic process	GO:0042534	10	0.056	Mouse
embryonic placenta development	GO:0001892	98	0.056
positive regulation of transferase activity	GO:0051347	167	0.056
response to acid chemical	GO:0001101	111	0.056
positive regulation of tumor necrosis factor superfamily cytokine production	GO:1903557	31	0.056	Mouse
ras protein signal transduction	GO:0007265	77	0.056
regulation of kinase activity	GO:0043549	249	0.055
tissue homeostasis	GO:0001894	115	0.055
branching morphogenesis of an epithelial tube	GO:0048754	159	0.055
regulation of metal ion transport	GO:0010959	106	0.055	Mouse
single organismal cell cell adhesion	GO:0016337	131	0.055
regulation of acute inflammatory response	GO:0002673	27	0.055
microglial cell activation	GO:0001774	3	0.054
jnk cascade	GO:0007254	72	0.054
defense response to bacterium	GO:0042742	119	0.054	Mouse
neural precursor cell proliferation	GO:0061351	121	0.054
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.054
positive regulation of b cell mediated immunity	GO:0002714	26	0.054
regulation of interleukin 12 production	GO:0032655	30	0.053
leukocyte apoptotic process	GO:0071887	71	0.053
glial cell development	GO:0021782	54	0.053
regulation of protein kinase activity	GO:0045859	232	0.052
regulation of alpha beta t cell activation	GO:0046634	53	0.052
locomotory behavior	GO:0007626	195	0.052
axon ensheathment	GO:0008366	76	0.052
fatty acid biosynthetic process	GO:0006633	41	0.052
cytoplasmic transport	GO:0016482	234	0.052	Mouse
interleukin 2 production	GO:0032623	33	0.052
striated muscle tissue development	GO:0014706	293	0.051
regionalization	GO:0003002	337	0.051
ion transmembrane transport	GO:0034220	361	0.050
positive regulation of behavior	GO:0048520	40	0.050
regulation of interferon gamma production	GO:0032649	57	0.050
regulation of binding	GO:0051098	111	0.050
positive regulation of leukocyte differentiation	GO:1902107	86	0.050
epidermis development	GO:0008544	187	0.050
response to transforming growth factor beta	GO:0071559	88	0.050
regulation of tumor necrosis factor superfamily cytokine production	GO:1903555	50	0.050	Mouse
protein localization to organelle	GO:0033365	185	0.050
dendritic cell differentiation	GO:0097028	26	0.049
positive regulation of phospholipase c activity	GO:0010863	2	0.049
canonical wnt signaling pathway	GO:0060070	130	0.049
cell cell recognition	GO:0009988	44	0.049
organic acid biosynthetic process	GO:0016053	86	0.049
positive regulation of jnk cascade	GO:0046330	46	0.048
regulation of cellular catabolic process	GO:0031329	242	0.048
neutrophil chemotaxis	GO:0030593	36	0.048
positive regulation of interleukin 12 production	GO:0032735	21	0.047
regulation of cytoplasmic transport	GO:1903649	112	0.047	Mouse
camera type eye development	GO:0043010	266	0.047
epithelial cell development	GO:0002064	159	0.047
protein secretion	GO:0009306	111	0.047	Mouse
regulation of canonical wnt signaling pathway	GO:0060828	82	0.047
regulation of cell projection organization	GO:0031344	206	0.046
neuron projection guidance	GO:0097485	141	0.046
positive regulation of lymphocyte migration	GO:2000403	11	0.046
granulocyte chemotaxis	GO:0071621	39	0.046
cellular lipid metabolic process	GO:0044255	323	0.046
divalent metal ion transport	GO:0070838	172	0.046	Mouse
positive regulation of cell death	GO:0010942	224	0.046
peptidyl tyrosine phosphorylation	GO:0018108	143	0.046
leukocyte migration	GO:0050900	124	0.046
multicellular organismal homeostasis	GO:0048871	164	0.046
positive regulation of inflammatory response to antigenic stimulus	GO:0002863	11	0.046
ossification	GO:0001503	216	0.045
positive regulation of t cell differentiation	GO:0045582	52	0.045
germ cell development	GO:0007281	185	0.045
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002824	61	0.045
cell maturation	GO:0048469	127	0.044
neuron death	GO:0070997	154	0.044
positive regulation of lymphocyte differentiation	GO:0045621	61	0.044
cellular defense response	GO:0006968	6	0.043
regulation of striated muscle cell differentiation	GO:0051153	81	0.043
alpha beta t cell differentiation	GO:0046632	69	0.043
response to organic cyclic compound	GO:0014070	198	0.043
synaptic transmission	GO:0007268	329	0.043
male gamete generation	GO:0048232	285	0.042
stress activated protein kinase signaling cascade	GO:0031098	81	0.041
signal transduction in absence of ligand	GO:0038034	55	0.041
macrophage activation	GO:0042116	27	0.041
positive regulation of secretion by cell	GO:1903532	114	0.041	Mouse
negative regulation of cellular protein metabolic process	GO:0032269	247	0.041
regulation of neuron death	GO:1901214	134	0.041
carboxylic acid biosynthetic process	GO:0046394	86	0.041
nitrogen compound transport	GO:0071705	271	0.041
dendritic cell chemotaxis	GO:0002407	7	0.041
regulation of ossification	GO:0030278	112	0.041
negative regulation of intracellular signal transduction	GO:1902532	167	0.040
interleukin 12 production	GO:0032615	32	0.040
regulation of secretion	GO:0051046	274	0.039	Mouse
positive regulation of neuron differentiation	GO:0045666	141	0.039
interleukin 1 secretion	GO:0050701	16	0.039
peptidyl amino acid modification	GO:0018193	336	0.038
axon guidance	GO:0007411	141	0.038
regulation of multi organism process	GO:0043900	111	0.038	Human
telencephalon cell migration	GO:0022029	55	0.038
regulation of erythrocyte differentiation	GO:0045646	23	0.038
regulation of lymphocyte mediated immunity	GO:0002706	84	0.038
stress activated mapk cascade	GO:0051403	80	0.038
positive regulation of apoptotic process	GO:0043065	217	0.038
regulation of neuron differentiation	GO:0045664	281	0.037
cellular response to organonitrogen compound	GO:0071417	145	0.037
tissue remodeling	GO:0048771	102	0.037
negative regulation of defense response	GO:0031348	77	0.037
hemostasis	GO:0007599	78	0.037
regulation of system process	GO:0044057	200	0.037
platelet activation	GO:0030168	40	0.037
negative regulation of leukocyte mediated immunity	GO:0002704	29	0.037	Mouse
cation transmembrane transport	GO:0098655	266	0.037
lipopolysaccharide mediated signaling pathway	GO:0031663	25	0.037
sensory perception of pain	GO:0019233	47	0.036
phosphatidylinositol 3 kinase signaling	GO:0014065	36	0.036
i kappab kinase nf kappab signaling	GO:0007249	85	0.036	Mouse
regulation of exocytosis	GO:0017157	61	0.036
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	40	0.036
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.036
positive regulation of alpha beta t cell proliferation	GO:0046641	12	0.035
lymphocyte homeostasis	GO:0002260	64	0.035
protein maturation	GO:0051604	176	0.034
b cell activation involved in immune response	GO:0002312	50	0.034
kidney development	GO:0001822	213	0.034
positive regulation of cellular component biogenesis	GO:0044089	94	0.034
immunoglobulin mediated immune response	GO:0016064	69	0.034
positive regulation of glial cell differentiation	GO:0045687	21	0.034
urogenital system development	GO:0001655	261	0.034
cd4 positive alpha beta t cell differentiation	GO:0043367	41	0.034
regulation of t cell proliferation	GO:0042129	92	0.034	Mouse
regulation of hormone levels	GO:0010817	211	0.034
regulation of cellular component size	GO:0032535	121	0.034
small gtpase mediated signal transduction	GO:0007264	97	0.033
regulation of jnk cascade	GO:0046328	62	0.033
protein targeting	GO:0006605	143	0.033
regulation of granulocyte chemotaxis	GO:0071622	17	0.033
cell division	GO:0051301	120	0.033
leukocyte proliferation	GO:0070661	172	0.033	Mouse
mesenchyme development	GO:0060485	152	0.033
amide transport	GO:0042886	138	0.033
negative regulation of cell development	GO:0010721	169	0.033
regulation of organelle organization	GO:0033043	289	0.033
peptide transport	GO:0015833	133	0.033
endocytosis	GO:0006897	168	0.033	Mouse
small molecule biosynthetic process	GO:0044283	132	0.032
leukocyte homeostasis	GO:0001776	79	0.032
positive regulation of gliogenesis	GO:0014015	27	0.032
dna metabolic process	GO:0006259	303	0.032
mast cell activation involved in immune response	GO:0002279	20	0.032
negative regulation of cellular amine metabolic process	GO:0033239	1	0.032
negative regulation of immune effector process	GO:0002698	55	0.032	Mouse
peptidyl tyrosine modification	GO:0018212	145	0.032
anatomical structure homeostasis	GO:0060249	145	0.032
response to interferon gamma	GO:0034341	34	0.031
regulation of production of molecular mediator of immune response	GO:0002700	65	0.031
positive regulation of glycoprotein metabolic process	GO:1903020	6	0.031
cardiac chamber morphogenesis	GO:0003206	93	0.031
apoptotic signaling pathway	GO:0097190	306	0.031
endocrine system development	GO:0035270	98	0.031
cellular response to lipid	GO:0071396	145	0.031
jak stat cascade	GO:0007259	42	0.031
positive regulation of t cell proliferation	GO:0042102	52	0.031
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.030
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	45	0.030
negative regulation of exocytosis	GO:0045920	12	0.030
regulation of peptide transport	GO:0090087	91	0.030
nephron development	GO:0072006	109	0.030
nucleocytoplasmic transport	GO:0006913	139	0.030
t cell migration	GO:0072678	19	0.030
regulation of myeloid leukocyte mediated immunity	GO:0002886	25	0.030
epithelial cell proliferation	GO:0050673	174	0.030
nuclear transport	GO:0051169	139	0.030
positive regulation of cellular catabolic process	GO:0031331	148	0.029
monocarboxylic acid biosynthetic process	GO:0072330	61	0.029
positive regulation of interferon gamma production	GO:0032729	39	0.029
cell recognition	GO:0008037	83	0.029	Mouse
regulation of extrinsic apoptotic signaling pathway in absence of ligand	GO:2001239	26	0.029
forebrain cell migration	GO:0021885	58	0.029
leukocyte mediated immunity	GO:0002443	174	0.029
positive regulation of stress activated mapk cascade	GO:0032874	48	0.029
organonitrogen compound biosynthetic process	GO:1901566	192	0.029
negative regulation of vasculature development	GO:1901343	26	0.029
positive regulation of peptide secretion	GO:0002793	33	0.029
positive regulation of lymphocyte proliferation	GO:0050671	70	0.028
establishment of protein localization to organelle	GO:0072594	118	0.028
labyrinthine layer development	GO:0060711	49	0.028
glucose homeostasis	GO:0042593	128	0.028
positive regulation of oligodendrocyte differentiation	GO:0048714	9	0.028
negative t cell selection	GO:0043383	13	0.028
positive regulation of alpha beta t cell activation	GO:0046635	39	0.028
positive regulation of antigen receptor mediated signaling pathway	GO:0050857	9	0.027
negative regulation of molecular function	GO:0044092	258	0.027
posttranscriptional regulation of gene expression	GO:0010608	155	0.027
organelle assembly	GO:0070925	177	0.027
cerebral cortex cell migration	GO:0021795	44	0.027
cd4 positive alpha beta t cell differentiation involved in immune response	GO:0002294	28	0.027
extracellular matrix organization	GO:0030198	147	0.027
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.027
response to nutrient levels	GO:0031667	109	0.027
regulation of nucleocytoplasmic transport	GO:0046822	73	0.026
lymphocyte migration	GO:0072676	26	0.026
neutrophil migration	GO:1990266	37	0.026
negative regulation of protein modification process	GO:0031400	163	0.026
positive regulation of protein kinase activity	GO:0045860	144	0.026
negative regulation of ossification	GO:0030279	49	0.026
regulation of cell cycle process	GO:0010564	160	0.026
extracellular structure organization	GO:0043062	148	0.026
response to organonitrogen compound	GO:0010243	246	0.026
negative regulation of secretion	GO:0051048	61	0.026
regulation of organ morphogenesis	GO:2000027	144	0.026
hypersensitivity	GO:0002524	10	0.026
positive regulation of acute inflammatory response	GO:0002675	16	0.026
t cell costimulation	GO:0031295	14	0.026
positive regulation of antigen processing and presentation	GO:0002579	10	0.025
positive regulation of homeostatic process	GO:0032846	64	0.025	Mouse
lymphocyte apoptotic process	GO:0070227	54	0.025
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.025
organic hydroxy compound transport	GO:0015850	93	0.025
skeletal muscle organ development	GO:0060538	163	0.025
odontogenesis of dentin containing tooth	GO:0042475	66	0.025

Fcer2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
immune system disease	DOID:2914	0.142
disease of anatomical entity	DOID:7	0.142
primary immunodeficiency disease	DOID:612	0.074
musculoskeletal system disease	DOID:17	0.036
connective tissue disease	DOID:65	0.036
disease of cellular proliferation	DOID:14566	0.035
viral infectious disease	DOID:934	0.032
disease by infectious agent	DOID:0050117	0.032
arthritis	DOID:848	0.029
rheumatoid arthritis	DOID:7148	0.029
bone disease	DOID:0080001	0.029
bone inflammation disease	DOID:3342	0.029
human immunodeficiency virus infectious disease	DOID:526	0.026

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