Mus musculus

5 known processes

Mdh2

malate dehydrogenase 2, NAD (mitochondrial)

(Aliases: MDH,Mor1,Mdh-2,Mor-1)

Mdh2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
citrate metabolic processGO:000610130.989
oxidation reduction processGO:00551143420.943
nadh metabolic processGO:000673410.916
atp metabolic processGO:0046034750.872
generation of precursor metabolites and energyGO:00060911030.861
Fly
cellular respirationGO:0045333380.849
Fly
energy derivation by oxidation of organic compoundsGO:0015980770.789
Fly
nucleoside triphosphate metabolic processGO:00091412300.779
nucleoside phosphate metabolic processGO:00067533380.765
nucleotide metabolic processGO:00091173320.673
tricarboxylic acid metabolic processGO:007235050.589
intrinsic apoptotic signaling pathwayGO:00971931320.583
purine nucleoside triphosphate metabolic processGO:00091442260.517
purine ribonucleoside triphosphate metabolic processGO:00092052200.396
nucleoside monophosphate metabolic processGO:0009123850.396
glycosyl compound metabolic processGO:19016572460.395
purine ribonucleoside monophosphate metabolic processGO:0009167800.364
purine containing compound metabolic processGO:00725213110.357
purine ribonucleotide metabolic processGO:00091502900.356
nucleobase containing small molecule metabolic processGO:00550863520.342
ribonucleoside metabolic processGO:00091192450.328
purine nucleoside monophosphate metabolic processGO:0009126810.328
purine nucleotide metabolic processGO:00061633020.321
coenzyme metabolic processGO:0006732520.318
purine nucleoside metabolic processGO:00422782410.297
nucleoside metabolic processGO:00091162460.257
ribonucleotide metabolic processGO:00092592910.244
hydrogen ion transmembrane transportGO:1902600250.244
oxidative phosphorylationGO:0006119140.238
oxidoreduction coenzyme metabolic processGO:0006733160.228
purine ribonucleoside metabolic processGO:00461282410.202
ion transmembrane transportGO:00342203610.186
ribose phosphate metabolic processGO:00196932910.184
multicellular organismal agingGO:0010259240.171
ribonucleoside triphosphate metabolic processGO:00091992200.167
carbohydrate derivative biosynthetic processGO:19011371830.165
nad metabolic processGO:001967470.137
transmembrane transportGO:00550854120.136
atp synthesis coupled electron transportGO:004277380.136
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.111
cation transportGO:00068123990.103
nucleoside phosphate biosynthetic processGO:1901293790.097
monocarboxylic acid metabolic processGO:00327871910.097
ribonucleoside monophosphate metabolic processGO:0009161800.095
inorganic ion transmembrane transportGO:00986602340.094
glycolytic processGO:0006096200.093
mitochondrial electron transport ubiquinol to cytochrome cGO:000612220.091
hydrogen transportGO:0006818350.077
apoptotic signaling pathwayGO:00971903060.074
coenzyme biosynthetic processGO:0009108230.074
heterocycle catabolic processGO:00467002800.073
determination of adult lifespanGO:0008340110.072
inorganic cation transmembrane transportGO:00986622070.068
cation transmembrane transportGO:00986552660.062
purine ribonucleoside biosynthetic processGO:0046129190.062
organophosphate biosynthetic processGO:00904071220.061
anatomical structure homeostasisGO:00602491450.060
purine ribonucleotide biosynthetic processGO:0009152590.056
purine nucleoside triphosphate catabolic processGO:00091462030.056
aromatic compound catabolic processGO:00194392860.055
aerobic respirationGO:000906070.054
Fly
carbohydrate catabolic processGO:0016052320.053
carbohydrate metabolic processGO:00059752300.053
endocytosisGO:00068971680.052
proton transportGO:0015992350.052
purine nucleoside monophosphate biosynthetic processGO:000912790.050
metal ion homeostasisGO:00550651890.049
carbohydrate derivative catabolic processGO:19011362310.047
ribonucleoside monophosphate biosynthetic processGO:000915690.046
purine nucleotide biosynthetic processGO:0006164650.046
cellular ketone metabolic processGO:0042180840.046
negative regulation of cell proliferationGO:00082852960.045
spermatogenesisGO:00072832840.041
cofactor transportGO:005118140.040
cellular ion homeostasisGO:00068731650.040
heme transportGO:001588620.039
gonad developmentGO:00084061410.038
atp catabolic processGO:0006200550.037
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244250.036
purine ribonucleoside triphosphate catabolic processGO:00092071990.036
synaptic transmissionGO:00072683290.035
regulation of apoptotic signaling pathwayGO:20012331970.035
purine nucleoside biosynthetic processGO:0042451190.035
regulation of nucleotide metabolic processGO:00061401690.035
anion transportGO:00068201770.034
nucleotide catabolic processGO:00091662170.034
glycosyl compound catabolic processGO:19016582060.033
succinyl coa metabolic processGO:000610410.033
development of primary sexual characteristicsGO:00451371430.033
positive regulation of proteolysisGO:0045862850.032
Fly
cofactor metabolic processGO:0051186800.032
epithelial cell proliferationGO:00506731740.032
reactive oxygen species metabolic processGO:0072593840.031
neurotransmitter transportGO:0006836760.031
monosaccharide metabolic processGO:00059961060.031
cellular macromolecule catabolic processGO:00442652060.030
purine containing compound catabolic processGO:00725232130.030
cellular lipid metabolic processGO:00442553230.030
nicotinamide nucleotide metabolic processGO:0046496120.030
regulation of epithelial cell proliferationGO:00506781410.029
muscle system processGO:00030121410.029
mitochondrial atp synthesis coupled electron transportGO:004277580.029
nitrogen compound transportGO:00717052710.029
ribose phosphate biosynthetic processGO:0046390590.028
nucleoside triphosphate catabolic processGO:00091432050.028
positive regulation of cell deathGO:00109422240.028
Fly
positive regulation of cellular amino acid metabolic processGO:004576430.026
pyridine nucleotide metabolic processGO:0019362120.025
regulation of atp metabolic processGO:1903578170.025
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.025
regulation of ion transportGO:00432692150.025
purine nucleoside triphosphate biosynthetic processGO:000914570.025
nucleoside catabolic processGO:00091642060.024
substantia nigra developmentGO:002176220.024
regulation of atp biosynthetic processGO:200116930.024
regulation of purine nucleotide metabolic processGO:19005421690.024
positive regulation of apoptotic processGO:00430652170.023
Fly
nucleotide biosynthetic processGO:0009165780.023
macromolecule catabolic processGO:00090572810.022
endothelial cell proliferationGO:0001935270.022
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.022
Fly
regulation of oxidative phosphorylation uncoupler activityGO:200027530.021
positive regulation of hydrolase activityGO:00513451480.021
Fly
regulation of proteolysisGO:00301621640.021
Fly
response to oxygen levelsGO:0070482620.021
cellular homeostasisGO:00197252400.021
positive regulation of purine nucleotide metabolic processGO:19005441140.021
regulation of cellular amino acid metabolic processGO:000652150.021
locomotory behaviorGO:00076261950.020
morphogenesis of a branching epitheliumGO:00611381930.020
neural tube formationGO:00018411080.020
purine ribonucleotide catabolic processGO:00091542080.020
cation homeostasisGO:00550802120.020
aldehyde catabolic processGO:004618540.020
cytoplasmic transportGO:00164822340.019
positive regulation of growthGO:00459271040.019
cellular amine metabolic processGO:0044106440.019
regulation of lymphocyte activationGO:00512492400.019
cellular amino acid metabolic processGO:00065201030.019
lactate biosynthetic processGO:001924940.019
genitalia developmentGO:0048806370.018
organic anion transportGO:00157111370.018
regulation of neurotransmitter levelsGO:0001505870.018
ribonucleoside catabolic processGO:00424542060.018
action potentialGO:0001508780.018
purine ribonucleoside triphosphate biosynthetic processGO:000920660.018
epithelial tube morphogenesisGO:00605623030.018
positive regulation of apoptotic signaling pathwayGO:2001235950.018
regulation of nucleoside metabolic processGO:00091181300.018
myosin filament organizationGO:003103330.018
positive regulation of cellular amine metabolic processGO:003324050.018
regulation of cell activationGO:00508652890.018
regulation of membrane potentialGO:00423911920.018
cell growthGO:00160491300.018
blood vessel morphogenesisGO:00485142850.018
ribonucleoside monophosphate catabolic processGO:0009158570.017
purine nucleoside catabolic processGO:00061522050.017
adult locomotory behaviorGO:0008344910.017
organelle localizationGO:00516401790.016
organic acid transportGO:00158491010.016
regulation of organelle organizationGO:00330432890.016
adult behaviorGO:00305341350.016
protein catabolic processGO:00301632210.016
response to organonitrogen compoundGO:00102432460.016
negative regulation of growthGO:0045926990.016
response to radiationGO:00093141650.016
regulation of cellular amine metabolic processGO:0033238200.016
cellular metal ion homeostasisGO:00068751510.015
pentose phosphate shuntGO:000609820.015
pyridine containing compound metabolic processGO:0072524140.015
organonitrogen compound biosynthetic processGO:19015661920.015
glycosyl compound biosynthetic processGO:1901659210.015
nucleoside phosphate catabolic processGO:19012922220.015
purine ribonucleoside monophosphate catabolic processGO:0009169570.015
regulation of purine nucleotide biosynthetic processGO:1900371340.015
organic hydroxy compound biosynthetic processGO:1901617770.015
regulation of hydrolase activityGO:00513362460.014
Fly
positive regulation of nucleoside metabolic processGO:0045979910.014
multicellular organismal homeostasisGO:00488711640.014
cytosolic calcium ion homeostasisGO:0051480700.014
ribonucleoside triphosphate catabolic processGO:00092031990.014
response to oxidative stressGO:00069791230.014
cellular protein complex assemblyGO:00436231160.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
purine containing compound biosynthetic processGO:0072522700.014
regulation of inflammatory responseGO:00507271470.014
maintenance of locationGO:0051235890.014
regulation of cellular catabolic processGO:00313292420.013
multicellular organism growthGO:00352641610.013
regulation of protein ubiquitinationGO:0031396520.013
extrinsic apoptotic signaling pathwayGO:00971911260.013
regulation of transferase activityGO:00513382630.013
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.013
positive regulation of transmembrane transportGO:0034764290.013
posttranscriptional regulation of gene expressionGO:00106081550.013
male gamete generationGO:00482322850.013
negative regulation of intracellular signal transductionGO:19025321670.013
organophosphate catabolic processGO:00464342320.013
positive regulation of protein modification processGO:00314012990.013
homeostasis of number of cellsGO:00488722100.013
adenine nucleotide transportGO:005150320.013
receptor mediated endocytosisGO:0006898510.013
attachment of spindle microtubules to kinetochoreGO:000860840.012
nucleoside monophosphate catabolic processGO:0009125590.012
cellular nitrogen compound catabolic processGO:00442702800.012
amine metabolic processGO:0009308450.012
divalent inorganic cation homeostasisGO:00725071380.012
cellular response to oxidative stressGO:0034599760.012
synaptic vesicle transportGO:0048489570.012
regulation of cellular ketone metabolic processGO:0010565660.012
positive regulation of nucleotide metabolic processGO:00459811140.012
inflammatory responseGO:00069542440.012
regulation of transporter activityGO:0032409570.012
g protein coupled receptor signaling pathwayGO:00071862430.012
hexose catabolic processGO:001932030.012
cellular chemical homeostasisGO:00550822150.012
striated muscle tissue developmentGO:00147062930.012
sensory perceptionGO:00076002450.012
regulation of neuron deathGO:19012141340.012
carboxylic acid transportGO:00469421000.012
regulation of transmembrane transportGO:00347621280.012
organism emergence from protective structureGO:007168440.012
nucleoside monophosphate biosynthetic processGO:0009124120.011
response to organic cyclic compoundGO:00140701980.011
mitochondrial calcium ion homeostasisGO:005156070.011
negative regulation of cellular protein metabolic processGO:00322692470.011
positive regulation of programmed cell deathGO:00430682180.011
Fly
quinone biosynthetic processGO:190166340.011
regulation of cytokine productionGO:00018172660.011
tissue homeostasisGO:00018941150.011
cellular response to organonitrogen compoundGO:00714171450.011
positive regulation of nucleotide biosynthetic processGO:0030810260.011
purine nucleotide catabolic processGO:00061952110.011
branching morphogenesis of an epithelial tubeGO:00487541590.011
peptidyl amino acid modificationGO:00181933360.011
iron coordination entity transportGO:190167850.011
cytokine productionGO:00018163190.011
regulation of peptidase activityGO:0052547960.011
Fly
epithelial cell developmentGO:00020641590.011
dicarboxylic acid metabolic processGO:0043648180.011
Human
negative regulation of cellular component organizationGO:00511291940.011
lateral inhibitionGO:004633110.011
neuron deathGO:00709971540.011
organic hydroxy compound transportGO:0015850930.010
multi multicellular organism processGO:00447061090.010
l glutamate import into cellGO:199012330.010
porphyrin containing compound biosynthetic processGO:0006779160.010
regulation of interleukin 8 productionGO:003267730.010
negative regulation of phosphorylationGO:00423261660.010
response to molecule of bacterial originGO:00022371430.010

Mdh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
hematopoietic system diseaseDOID:7400.157
immune system diseaseDOID:291400.157
disease of anatomical entityDOID:700.157
nervous system diseaseDOID:86300.090
disease of cellular proliferationDOID:1456600.052
cancerDOID:16200.052
disease of metabolismDOID:001466700.040
inherited metabolic disorderDOID:65500.030
central nervous system diseaseDOID:33100.019
neurodegenerative diseaseDOID:128900.015
organ system cancerDOID:005068600.013
eye and adnexa diseaseDOID:149200.012
eye diseaseDOID:561400.012
sensory system diseaseDOID:005015500.012
cell type benign neoplasmDOID:006008400.010
phaeochromocytomaDOID:005077100.010
benign neoplasmDOID:006007200.010