Mus musculus

16 known processes

Tfam

transcription factor A, mitochondrial

(Aliases: Hmgts,AI661103,tsHMG,mtTFA)

Tfam biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense response to other organismGO:00985421970.462
dna metabolic processGO:00062593030.355
protein processingGO:00164851630.233
apoptotic signaling pathwayGO:00971903060.209
cellular response to dna damage stimulusGO:00069742070.175
protein maturationGO:00516041760.162
positive regulation of cell deathGO:00109422240.138
cytokine productionGO:00018163190.136
cellular ketone metabolic processGO:0042180840.125
macromolecule catabolic processGO:00090572810.117
purine ribonucleotide metabolic processGO:00091502900.115
mitochondrion organizationGO:00070051340.104
intrinsic apoptotic signaling pathwayGO:00971931320.102
glycosyl compound metabolic processGO:19016572460.101
immune effector processGO:00022523210.095
regulation of cell motilityGO:20001452360.094
regulation of cellular amino acid metabolic processGO:000652150.092
mitochondrial translationGO:003254340.090
protein catabolic processGO:00301632210.089
cellular amino acid metabolic processGO:00065201030.081
negative regulation of immune system processGO:00026832090.076
cellular nitrogen compound catabolic processGO:00442702800.076
purine nucleotide metabolic processGO:00061633020.071
regulation of protein processingGO:0070613960.070
regulation of defense responseGO:00313472330.070
activation of immune responseGO:00022531380.070
cellular macromolecule catabolic processGO:00442652060.069
ribose phosphate metabolic processGO:00196932910.065
peptidyl amino acid modificationGO:00181933360.065
heterocycle catabolic processGO:00467002800.064
regulation of protein maturationGO:1903317960.062
amine metabolic processGO:0009308450.061
rna processingGO:00063961050.061
ribonucleotide metabolic processGO:00092592910.061
regulation of cellular catabolic processGO:00313292420.061
purine containing compound metabolic processGO:00725213110.059
stem cell differentiationGO:00488632680.058
leukocyte differentiationGO:00025213420.058
histone modificationGO:00165701590.058
positive regulation of defense responseGO:00313491240.057
positive regulation of innate immune responseGO:0045089800.057
aromatic compound catabolic processGO:00194392860.057
oxidation reduction processGO:00551143420.057
regulation of cell migrationGO:00303342190.056
multicellular organismal homeostasisGO:00488711640.055
nucleotide metabolic processGO:00091173320.054
striated muscle tissue developmentGO:00147062930.054
response to oxidative stressGO:00069791230.052
nucleoside metabolic processGO:00091162460.052
dna repairGO:00062811070.051
cell adhesionGO:00071553290.051
organic cyclic compound catabolic processGO:19013612950.051
response to organonitrogen compoundGO:00102432460.051
cellular amine metabolic processGO:0044106440.051
cell type specific apoptotic processGO:00972852680.051
gonad developmentGO:00084061410.050
response to organic cyclic compoundGO:00140701980.049
regulation of cellular ketone metabolic processGO:0010565660.049
generation of precursor metabolites and energyGO:00060911030.048
chromatin organizationGO:00063252060.048
chromatin modificationGO:00165681870.048
neuron apoptotic processGO:00514021420.047
cellular chemical homeostasisGO:00550822150.047
purine nucleoside triphosphate metabolic processGO:00091442260.047
stem cell developmentGO:00488642190.047
regulation of innate immune responseGO:0045088910.046
regulation of cell morphogenesis involved in differentiationGO:00107691510.046
cellular metal ion homeostasisGO:00068751510.045
regulation of cellular amine metabolic processGO:0033238200.044
positive regulation of cell developmentGO:00107202370.044
regulation of proteolysisGO:00301621640.044
negative regulation of molecular functionGO:00440922580.044
inflammatory responseGO:00069542440.044
regulation of cytokine productionGO:00018172660.043
purine nucleoside metabolic processGO:00422782410.043
anatomical structure homeostasisGO:00602491450.042
gland developmentGO:00487323300.042
purine ribonucleoside metabolic processGO:00461282410.041
multi multicellular organism processGO:00447061090.040
regulation of kinase activityGO:00435492490.040
muscle cell differentiationGO:00426922610.040
regulation of protein kinase activityGO:00458592320.040
purine ribonucleoside triphosphate metabolic processGO:00092052200.040
negative regulation of phosphate metabolic processGO:00459361840.039
cellular response to lipidGO:00713961450.039
nucleobase containing small molecule metabolic processGO:00550863520.038
positive regulation of programmed cell deathGO:00430682180.038
myeloid cell differentiationGO:00300992330.038
regulation of chemotaxisGO:0050920530.038
posttranscriptional regulation of gene expressionGO:00106081550.037
multicellular organism growthGO:00352641610.037
leukocyte chemotaxisGO:0030595690.037
cellular homeostasisGO:00197252400.036
positive regulation of cellular amino acid metabolic processGO:004576430.035
purine ribonucleoside monophosphate metabolic processGO:0009167800.035
positive regulation of apoptotic processGO:00430652170.035
positive regulation of cytokine productionGO:00018191740.034
positive regulation of cell motilityGO:20001471160.034
negative regulation of cellular component organizationGO:00511291940.034
chemotaxisGO:00069352470.034
cation homeostasisGO:00550802120.033
regulation of apoptotic signaling pathwayGO:20012331970.033
regulation of cell activationGO:00508652890.033
production of molecular mediator of immune responseGO:00024401030.033
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.033
atp metabolic processGO:0046034750.032
regulation of t cell activationGO:00508631700.032
regulation of cell cycleGO:00517262810.031
negative regulation of cell proliferationGO:00082852960.031
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.031
regulation of leukocyte differentiationGO:19021051590.030
membrane organizationGO:00610242450.030
ribonucleoside triphosphate metabolic processGO:00091992200.030
ribonucleoside monophosphate metabolic processGO:0009161800.030
cell fate commitmentGO:00451652100.030
translationGO:0006412930.029
proteolysis involved in cellular protein catabolic processGO:00516031470.029
metal ion homeostasisGO:00550651890.029
blood vessel morphogenesisGO:00485142850.029
regulation of organelle organizationGO:00330432890.029
cellular respirationGO:0045333380.029
nucleic acid phosphodiester bond hydrolysisGO:0090305490.028
regulation of mitotic cell cycleGO:00073461260.028
regulation of inflammatory responseGO:00507271470.028
gliogenesisGO:00420631410.028
morphogenesis of embryonic epitheliumGO:00163311590.028
nucleoside phosphate metabolic processGO:00067533380.028
positive regulation of nervous system developmentGO:00519622210.027
response to lipopolysaccharideGO:00324961280.027
organelle assemblyGO:00709251770.027
regulation of lymphocyte activationGO:00512492400.027
covalent chromatin modificationGO:00165691630.027
regulation of secretion by cellGO:19035302490.027
dna catabolic processGO:0006308190.026
organelle fissionGO:00482851700.026
defense response to virusGO:0051607680.026
male gamete generationGO:00482322850.026
regulation of transferase activityGO:00513382630.026
epithelial cell proliferationGO:00506731740.026
t cell activationGO:00421102890.026
nitrogen compound transportGO:00717052710.025
myeloid leukocyte differentiationGO:00025731190.025
nucleoside monophosphate metabolic processGO:0009123850.025
lymphocyte mediated immunityGO:00024491390.025
positive regulation of protein modification processGO:00314012990.025
positive regulation of cellular amine metabolic processGO:003324050.025
digestive tract developmentGO:00485651900.025
nucleoside triphosphate metabolic processGO:00091412300.024
cellular response to organonitrogen compoundGO:00714171450.024
immune response regulating signaling pathwayGO:00027641250.024
neuron deathGO:00709971540.024
energy derivation by oxidation of organic compoundsGO:0015980770.024
digestive system developmentGO:00551232000.024
positive regulation of cell migrationGO:00303351090.023
innate immune responseGO:00450871570.023
dna replicationGO:0006260520.023
cellular response to organic cyclic compoundGO:0071407870.023
cellular response to extracellular stimulusGO:0031668810.023
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.023
regulation of cell adhesionGO:00301551540.023
cellular response to growth factor stimulusGO:00713631970.023
regulation of response to woundingGO:19030341890.023
circulatory system processGO:00030131970.023
protein targetingGO:00066051430.023
skeletal muscle organ developmentGO:00605381630.023
engulfment of apoptotic cellGO:004365230.023
cellular protein complex assemblyGO:00436231160.022
stem cell maintenanceGO:00198271300.022
regulation of multi organism processGO:00439001110.022
cellular response to molecule of bacterial originGO:0071219830.022
cellular response to oxidative stressGO:0034599760.022
positive regulation of proteolysisGO:0045862850.022
negative regulation of dna replicationGO:000815640.022
mitotic cell cycle processGO:19030471590.022
ossificationGO:00015032160.022
positive regulation of cell activationGO:00508671580.022
organonitrogen compound catabolic processGO:19015652640.022
positive regulation of growthGO:00459271040.022
negative regulation of apoptotic signaling pathwayGO:20012341040.022
negative regulation of cell cycleGO:00457861230.022
negative regulation of cellular protein metabolic processGO:00322692470.022
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.022
lymphocyte activation involved in immune responseGO:0002285930.022
response to growth factorGO:00708481980.021
positive regulation of apoptotic signaling pathwayGO:2001235950.021
regulation of body fluid levelsGO:00508781620.021
regulation of protein serine threonine kinase activityGO:00719001570.021
response to extracellular stimulusGO:00099911270.021
regulation of cellular response to stressGO:00801351590.021
negative regulation of protein modification processGO:00314001630.021
b cell activationGO:00421131610.020
organonitrogen compound biosynthetic processGO:19015661920.020
regulation of homeostatic processGO:00328441820.020
regulation of hormone levelsGO:00108172110.020
regulation of secretionGO:00510462740.020
response to testosteroneGO:003357430.020
maintenance of locationGO:0051235890.020
intracellular protein transportGO:00068862040.020
positive regulation of protein phosphorylationGO:00019342420.020
response to endoplasmic reticulum stressGO:0034976530.020
substrate adhesion dependent cell spreadingGO:0034446300.020
carbohydrate homeostasisGO:00335001280.019
reactive oxygen species metabolic processGO:0072593840.019
regulation of epithelial cell proliferationGO:00506781410.019
regulation of response to biotic stimulusGO:0002831380.019
skeletal system developmentGO:00015013560.019
muscle cell developmentGO:00550011330.019
peptidyl lysine modificationGO:0018205770.019
response to reactive oxygen speciesGO:0000302560.019
action potentialGO:0001508780.019
developmental cell growthGO:0048588840.019
positive regulation of kinase activityGO:00336741550.019
methylationGO:00322591340.019
cellular response to external stimulusGO:0071496880.019
leukocyte mediated immunityGO:00024431740.019
protein localization to organelleGO:00333651850.019
ubiquitin dependent protein catabolic processGO:00065111290.019
negative regulation of protein processingGO:0010955790.019
locomotory behaviorGO:00076261950.018
negative regulation of protein metabolic processGO:00512482820.018
regulation of lipid metabolic processGO:00192161180.018
muscle tissue developmentGO:00605373080.018
blood circulationGO:00080151950.018
establishment of protein localization to organelleGO:00725941180.018
lymphocyte differentiationGO:00300982420.018
ribonucleoside metabolic processGO:00091192450.018
regulation of hydrolase activityGO:00513362460.017
homeostasis of number of cellsGO:00488722100.017
regulation of cell cycle processGO:00105641600.017
immune response activating signal transductionGO:00027571160.017
protein modification by small protein conjugation or removalGO:00706472070.017
antimicrobial peptide productionGO:000277520.017
urogenital system developmentGO:00016552610.017
negative regulation of protein maturationGO:1903318790.017
glucose homeostasisGO:00425931280.017
leukocyte activation involved in immune responseGO:00023661260.017
regulation of establishment of protein localizationGO:00702011810.017
regulation of cellular component biogenesisGO:00440871810.017
cellular protein catabolic processGO:00442571550.017
lipid biosynthetic processGO:00086101790.017
negative regulation of hydrolase activityGO:0051346710.017
forebrain developmentGO:00309003020.017
purine containing compound catabolic processGO:00725232130.017
cell growthGO:00160491300.017
positive regulation of dendritic cell chemotaxisGO:200051010.017
purine nucleoside monophosphate metabolic processGO:0009126810.017
striated muscle cell developmentGO:00550021250.017
ras protein signal transductionGO:0007265770.017
intracellular receptor signaling pathwayGO:0030522740.017
regulation of vesicle mediated transportGO:00606271390.017
response to peptideGO:19016521360.017
renal system developmentGO:00720012250.017
humoral immune responseGO:0006959570.017
cellular response to hormone stimulusGO:00328701500.017
negative regulation of phosphorus metabolic processGO:00105631840.016
regulation of protein transportGO:00512231630.016
negative regulation of cell cycle phase transitionGO:1901988480.016
transmembrane transportGO:00550854120.016
nucleotide excision repairGO:0006289130.016
regulation of mitochondrial translationGO:007012930.016
cell activation involved in immune responseGO:00022631260.016
endocytosisGO:00068971680.016
purine ribonucleotide biosynthetic processGO:0009152590.016
adaptive immune responseGO:00022501550.016
positive regulation of cell adhesionGO:0045785800.016
innate immune response activating signal transductionGO:0002758500.016
sensory perceptionGO:00076002450.016
tissue homeostasisGO:00018941150.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.016
protein importGO:00170381010.016
myotube differentiationGO:00149021050.016
meiotic cell cycleGO:00513211220.016
regulation of cell cycle phase transitionGO:1901987770.016
small gtpase mediated signal transductionGO:0007264970.016
regulation of dendritic cell chemotaxisGO:200050810.016
synaptic transmissionGO:00072683290.015
regulation of striated muscle cell differentiationGO:0051153810.015
negative regulation of cytokine productionGO:0001818840.015
protein ubiquitinationGO:00165671710.015
g protein coupled receptor signaling pathwayGO:00071862430.015
muscle contractionGO:00069361010.015
leukocyte proliferationGO:00706611720.015
muscle fiber developmentGO:0048747760.015
double strand break repairGO:0006302480.015
mapk cascadeGO:00001652810.015
positive regulation of lymphocyte activationGO:00512511400.015
interferon gamma productionGO:0032609670.015
neuron migrationGO:00017641220.015
modification dependent protein catabolic processGO:00199411330.015
regulation of protein catabolic processGO:00421761080.015
positive regulation of transferase activityGO:00513471670.015
regulation of neuron differentiationGO:00456642810.014
regulation of translationGO:0006417710.014
cytoplasmic transportGO:00164822340.014
single organism cell adhesionGO:00986021560.014
protein localization to membraneGO:00726571080.014
rhythmic processGO:00485111740.014
developmental growth involved in morphogenesisGO:00605601380.014
mitochondrial transportGO:0006839360.014
regulation of membrane potentialGO:00423911920.014
execution phase of apoptosisGO:0097194190.014
meiotic cell cycle processGO:1903046770.014
negative regulation of cell cycle processGO:0010948690.014
mitotic cell cycleGO:00002781950.014
regulation of adaptive immune responseGO:0002819900.014
nucleoside catabolic processGO:00091642060.014
negative regulation of immune effector processGO:0002698550.014
microtubule cytoskeleton organizationGO:00002261570.014
negative regulation of interferon gamma productionGO:0032689180.014
protein acylationGO:0043543640.014
chromosome segregationGO:0007059480.014
cell cycle g1 s phase transitionGO:0044843570.014
digestive tract morphogenesisGO:00485461470.013
macromolecule methylationGO:00434141200.013
nuclear transportGO:00511691390.013
ribonucleoprotein complex subunit organizationGO:0071826280.013
defense response to bacteriumGO:00427421190.013
cellular response to lipopolysaccharideGO:0071222770.013
regulation of system processGO:00440572000.013
germ cell developmentGO:00072811850.013
negative regulation of mitotic cell cycle phase transitionGO:1901991450.013
divalent inorganic cation homeostasisGO:00725071380.013
transmission of nerve impulseGO:0019226760.013
cell chemotaxisGO:0060326810.013
mrna metabolic processGO:0016071840.013
heart processGO:0003015940.013
pattern recognition receptor signaling pathwayGO:0002221470.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
cation transportGO:00068123990.013
response to nutrient levelsGO:00316671090.013
immunoglobulin mediated immune responseGO:0016064690.013
somatic diversification of immunoglobulinsGO:0016445430.013
regulation of lymphocyte differentiationGO:00456191070.013
mitochondrial membrane organizationGO:0007006260.013
cell substrate adhesionGO:00315891300.013
monosaccharide metabolic processGO:00059961060.013
cognitionGO:00508901490.013
apoptotic nuclear changesGO:003026290.013
regulation of protein localizationGO:00328802310.013
telencephalon developmentGO:00215371860.013
response to molecule of bacterial originGO:00022371430.013
negative regulation of organelle organizationGO:0010639900.012
positive regulation of organelle organizationGO:00106381280.012
response to steroid hormoneGO:0048545560.012
histone acetylationGO:0016573410.012
regulation of synaptic growth at neuromuscular junctionGO:000858240.012
defecationGO:003042110.012
epithelial tube morphogenesisGO:00605623030.012
proteasomal protein catabolic processGO:0010498980.012
cofactor biosynthetic processGO:0051188410.012
purine ribonucleoside catabolic processGO:00461302050.012
histone lysine methylationGO:0034968500.012
immunoglobulin productionGO:0002377730.012
neutrophil chemotaxisGO:0030593360.012
regulation of antimicrobial humoral responseGO:000275930.012
regulation of peptidase activityGO:0052547960.012
regulation of mitochondrion organizationGO:0010821270.012
phagocytosisGO:0006909660.012
gastrulationGO:00073691160.012
glial cell differentiationGO:00100011310.012
regulation of cysteine type endopeptidase activityGO:2000116650.012
apoptotic dna fragmentationGO:000630970.012
amide transportGO:00428861380.011
wnt signaling pathwayGO:00160551880.011
protein secretionGO:00093061110.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
male sex differentiationGO:00466611090.011
divalent inorganic cation transportGO:00725111780.011
negative regulation of intracellular signal transductionGO:19025321670.011
organic hydroxy compound transportGO:0015850930.011
meiotic nuclear divisionGO:00071261150.011
regulation of myeloid cell differentiationGO:0045637960.011
cellular response to peptideGO:1901653920.011
dna recombinationGO:0006310920.011
protein import into peroxisome matrixGO:001655830.011
lateral inhibitionGO:004633110.011
angiogenesisGO:00015252010.011
positive regulation of cellular catabolic processGO:00313311480.011
cellular response to biotic stimulusGO:0071216920.011
positive regulation of lymphocyte proliferationGO:0050671700.011
negative regulation of proteolysisGO:0045861740.011
small molecule biosynthetic processGO:00442831320.011
connective tissue developmentGO:00614481790.011
ribonucleotide catabolic processGO:00092612080.011
dephosphorylationGO:00163111290.011
positive regulation of behaviorGO:0048520400.011
somatic stem cell maintenanceGO:0035019470.011
response to acid chemicalGO:00011011110.011
regulation of protein kinase b signalingGO:0051896560.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.011
peptidyl tyrosine phosphorylationGO:00181081430.010
adult locomotory behaviorGO:0008344910.010
ameboidal type cell migrationGO:00016671280.010
rig i signaling pathwayGO:003952940.010
regulation of lipid biosynthetic processGO:0046890540.010
regulation of steroid biosynthetic processGO:0050810260.010
developmental maturationGO:00217001930.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
nucleoside phosphate catabolic processGO:19012922220.010
skeletal muscle cell differentiationGO:0035914660.010
regulation of chromatin modificationGO:1903308570.010
regulation of mitotic cell cycle phase transitionGO:1901990730.010
cellular response to peptide hormone stimulusGO:0071375920.010
multicellular organismal signalingGO:0035637910.010
divalent metal ion transportGO:00708381720.010
negative regulation of neuron apoptotic processGO:0043524920.010
internal peptidyl lysine acetylationGO:0018393420.010

Tfam disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.019
nervous system diseaseDOID:86300.019
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
organ system cancerDOID:005068600.015
musculoskeletal system diseaseDOID:1700.014
neurodegenerative diseaseDOID:128900.012
central nervous system diseaseDOID:33100.012