Mus musculus

102 known processes

Insig2

insulin induced gene 2

(Aliases: Insig-2,2900053I11Rik,C730043J18Rik)

Insig2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organophosphate catabolic processGO:00464342320.092
alcohol metabolic processGO:00060661160.083
cellular lipid metabolic processGO:00442553230.080
organic cyclic compound catabolic processGO:19013612950.073
nucleobase containing small molecule metabolic processGO:00550863520.064
cellular amine metabolic processGO:0044106440.062
organic hydroxy compound metabolic processGO:19016152030.061
lipid biosynthetic processGO:00086101790.060
ubiquitin dependent protein catabolic processGO:00065111290.058
amine metabolic processGO:0009308450.058
glycerolipid metabolic processGO:00464861220.057
cellular ketone metabolic processGO:0042180840.056
glycerophospholipid metabolic processGO:0006650710.054
small molecule biosynthetic processGO:00442831320.050
cellular amino acid metabolic processGO:00065201030.049
carbohydrate derivative catabolic processGO:19011362310.049
macromolecule catabolic processGO:00090572810.046
nucleotide metabolic processGO:00091173320.045
nucleoside metabolic processGO:00091162460.043
nucleoside phosphate metabolic processGO:00067533380.043
glycosyl compound metabolic processGO:19016572460.043
ribonucleoside metabolic processGO:00091192450.042
phosphatidylethanolamine metabolic processGO:004633720.042
immune effector processGO:00022523210.042
proteolysis involved in cellular protein catabolic processGO:00516031470.039
organonitrogen compound catabolic processGO:19015652640.039
intracellular protein transportGO:00068862040.038
monocarboxylic acid metabolic processGO:00327871910.038
aromatic compound catabolic processGO:00194392860.037
ribonucleotide catabolic processGO:00092612080.036
protein catabolic processGO:00301632210.036
protein targetingGO:00066051430.036
nitrogen compound transportGO:00717052710.035
purine nucleoside metabolic processGO:00422782410.035
ribonucleoside triphosphate metabolic processGO:00091992200.035
regulation of cellular ketone metabolic processGO:0010565660.034
purine ribonucleotide catabolic processGO:00091542080.034
phospholipid metabolic processGO:0006644870.034
cellular nitrogen compound catabolic processGO:00442702800.033
cellular biogenic amine metabolic processGO:0006576280.033
purine containing compound metabolic processGO:00725213110.031
positive regulation of cellular amino acid metabolic processGO:004576430.031
nucleotide catabolic processGO:00091662170.030
purine ribonucleoside metabolic processGO:00461282410.030
membrane organizationGO:00610242450.030
leukocyte differentiationGO:00025213420.029
regulation of intracellular transportGO:00323861590.029
protein modification by small protein conjugation or removalGO:00706472070.029
organic anion transportGO:00157111370.028
regulation of cellular catabolic processGO:00313292420.028
glycosyl compound catabolic processGO:19016582060.028
heterocycle catabolic processGO:00467002800.028
cellular protein catabolic processGO:00442571550.027
transmembrane transportGO:00550854120.027
regulation of defense responseGO:00313472330.026
cytokine productionGO:00018163190.026
ribose phosphate metabolic processGO:00196932910.026
regulation of cytokine productionGO:00018172660.025
nucleoside triphosphate catabolic processGO:00091432050.025
cellular macromolecule catabolic processGO:00442652060.025
response to organonitrogen compoundGO:00102432460.025
modification dependent macromolecule catabolic processGO:00436321330.024
negative regulation of protein metabolic processGO:00512482820.024
purine nucleotide metabolic processGO:00061633020.024
nucleoside triphosphate metabolic processGO:00091412300.024
positive regulation of cellular amine metabolic processGO:003324050.024
ribonucleotide metabolic processGO:00092592910.024
purine containing compound catabolic processGO:00725232130.024
regulation of cellular amine metabolic processGO:0033238200.024
anion transportGO:00068201770.024
negative regulation of cellular component organizationGO:00511291940.023
lipid transportGO:0006869980.023
carbohydrate metabolic processGO:00059752300.023
intra golgi vesicle mediated transportGO:000689110.023
cell activation involved in immune responseGO:00022631260.022
purine nucleotide catabolic processGO:00061952110.022
leukocyte mediated immunityGO:00024431740.022
apoptotic signaling pathwayGO:00971903060.022
purine nucleoside triphosphate metabolic processGO:00091442260.022
nucleoside phosphate catabolic processGO:19012922220.022
endomembrane system organizationGO:00102561470.021
purine nucleoside triphosphate catabolic processGO:00091462030.021
organonitrogen compound biosynthetic processGO:19015661920.021
regulation of protein localizationGO:00328802310.021
purine ribonucleotide metabolic processGO:00091502900.021
purine ribonucleoside triphosphate catabolic processGO:00092071990.021
regulation of nucleotide metabolic processGO:00061401690.021
adaptive immune responseGO:00022501550.021
carboxylic acid biosynthetic processGO:0046394860.021
regulation of cellular amino acid metabolic processGO:000652150.020
regulation of organelle organizationGO:00330432890.020
t cell activationGO:00421102890.020
organophosphate biosynthetic processGO:00904071220.020
positive regulation of nervous system developmentGO:00519622210.020
negative regulation of immune system processGO:00026832090.020
small gtpase mediated signal transductionGO:0007264970.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.020
regulation of hormone levelsGO:00108172110.019
organophosphate ester transportGO:0015748280.019
ribonucleoside triphosphate catabolic processGO:00092031990.019
leukocyte activation involved in immune responseGO:00023661260.019
regulation of apoptotic signaling pathwayGO:20012331970.019
positive regulation of protein modification processGO:00314012990.019
nucleocytoplasmic transportGO:00069131390.019
positive regulation of hydrolase activityGO:00513451480.018
organic acid biosynthetic processGO:0016053860.018
cell type specific apoptotic processGO:00972852680.018
cellular homeostasisGO:00197252400.018
regulation of neuron projection developmentGO:00109751690.018
phosphatidylethanolamine biosynthetic processGO:000664620.018
neuron deathGO:00709971540.018
lipid localizationGO:00108761260.017
regulation of anatomical structure sizeGO:00900661780.017
small molecule catabolic processGO:0044282710.017
cell growthGO:00160491300.017
inflammatory responseGO:00069542440.017
protein importGO:00170381010.017
ribonucleoside catabolic processGO:00424542060.017
leukocyte proliferationGO:00706611720.017
regulation of lymphocyte activationGO:00512492400.017
establishment of protein localization to vacuoleGO:007266640.016
negative regulation of cellular protein metabolic processGO:00322692470.016
response to radiationGO:00093141650.016
response to oxidative stressGO:00069791230.016
negative regulation of intracellular signal transductionGO:19025321670.016
reactive oxygen species metabolic processGO:0072593840.016
regulation of leukocyte proliferationGO:00706631210.016
activation of immune responseGO:00022531380.016
lipoprotein metabolic processGO:0042157430.016
regulation of neuron apoptotic processGO:00435231220.016
b cell activationGO:00421131610.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.016
negative regulation of cell proliferationGO:00082852960.016
ossificationGO:00015032160.016
guanosine containing compound catabolic processGO:19010691440.016
nucleoside catabolic processGO:00091642060.016
regulation of cellular response to stressGO:00801351590.015
cdp choline pathwayGO:000665720.015
regulation of leukocyte mediated immunityGO:00027031040.015
organic hydroxy compound biosynthetic processGO:1901617770.015
camera type eye developmentGO:00430102660.015
hormone secretionGO:00468791280.015
regulation of cell motilityGO:20001452360.015
cation homeostasisGO:00550802120.015
mapk cascadeGO:00001652810.015
ion transmembrane transportGO:00342203610.015
gtp metabolic processGO:00460391440.015
negative regulation of cytokine productionGO:0001818840.015
regulation of neuron deathGO:19012141340.015
regulation of purine nucleotide catabolic processGO:00331211220.015
sensory perceptionGO:00076002450.015
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.015
regulation of hydrolase activityGO:00513362460.015
purine ribonucleoside catabolic processGO:00461302050.015
regulation of t cell activationGO:00508631700.015
regulation of lipid metabolic processGO:00192161180.015
regulation of cytoplasmic transportGO:19036491120.014
regulation of secretion by cellGO:19035302490.014
protein ubiquitinationGO:00165671710.014
establishment of protein localization to organelleGO:00725941180.014
adult behaviorGO:00305341350.014
glycerophospholipid biosynthetic processGO:0046474320.014
myeloid cell differentiationGO:00300992330.014
plasma membrane organizationGO:0007009900.014
cation transportGO:00068123990.014
chromatin organizationGO:00063252060.014
regulation of kinase activityGO:00435492490.014
action potentialGO:0001508780.014
negative regulation of molecular functionGO:00440922580.013
innate immune responseGO:00450871570.013
purine ribonucleoside triphosphate metabolic processGO:00092052200.013
modification dependent protein catabolic processGO:00199411330.013
neuron apoptotic processGO:00514021420.013
myeloid leukocyte differentiationGO:00025731190.013
spermatogenesisGO:00072832840.013
defense response to other organismGO:00985421970.013
negative regulation of defense responseGO:0031348770.013
regulation of membrane potentialGO:00423911920.013
lipoprotein biosynthetic processGO:0042158330.013
organic acid transportGO:00158491010.013
regulation of lymphocyte proliferationGO:00506701170.013
compound eye developmentGO:004874910.013
regulation of secretionGO:00510462740.013
organic acid catabolic processGO:0016054510.013
regulation of purine nucleotide metabolic processGO:19005421690.013
regulation of cell projection organizationGO:00313442060.013
regulation of transferase activityGO:00513382630.013
protein localization to vacuoleGO:007266540.013
positive regulation of nucleotide catabolic processGO:0030813880.013
positive regulation of secretionGO:00510471300.013
lymphocyte mediated immunityGO:00024491390.013
protein maturationGO:00516041760.013
response to inorganic substanceGO:0010035960.013
regulation of proteolysisGO:00301621640.013
neurotransmitter transportGO:0006836760.013
muscle cell differentiationGO:00426922610.013
regulation of cell migrationGO:00303342190.013
regulation of cell activationGO:00508652890.013
lymphocyte activation involved in immune responseGO:0002285930.013
positive regulation of secretion by cellGO:19035321140.013
positive regulation of cell developmentGO:00107202370.013
membrane fusionGO:0061025380.013
response to peptideGO:19016521360.013
cellular protein complex assemblyGO:00436231160.013
regulation of protein catabolic processGO:00421761080.012
cellular response to lipidGO:00713961450.012
membrane lipid metabolic processGO:0006643530.012
lymphocyte differentiationGO:00300982420.012
regulation of response to woundingGO:19030341890.012
regulation of protein transportGO:00512231630.012
organelle localizationGO:00516401790.012
response to endoplasmic reticulum stressGO:0034976530.012
alcohol biosynthetic processGO:0046165430.012
regulation of inflammatory responseGO:00507271470.012
cellular response to growth factor stimulusGO:00713631970.012
multicellular organismal signalingGO:0035637910.012
production of molecular mediator of immune responseGO:00024401030.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.012
oxidation reduction processGO:00551143420.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
response to light stimulusGO:00094161350.012
regulation of homeostatic processGO:00328441820.012
axonogenesisGO:00074092740.012
carbohydrate derivative biosynthetic processGO:19011371830.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.012
somatic diversification of immune receptorsGO:0002200530.012
male gamete generationGO:00482322850.012
g protein coupled receptor signaling pathwayGO:00071862430.012
protein lipidationGO:0006497280.012
establishment of protein localization to golgiGO:007260010.012
monocarboxylic acid biosynthetic processGO:0072330610.012
cellular chemical homeostasisGO:00550822150.012
lipid catabolic processGO:0016042690.012
protein modification by small protein conjugationGO:00324461870.012
cytoplasmic transportGO:00164822340.011
metal ion homeostasisGO:00550651890.011
protein targeting to vacuoleGO:000662330.011
skin developmentGO:00435882200.011
regulation of vesicle mediated transportGO:00606271390.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
cellular carbohydrate metabolic processGO:00442621190.011
locomotory behaviorGO:00076261950.011
peptidyl amino acid modificationGO:00181933360.011
regulation of protein serine threonine kinase activityGO:00719001570.011
synaptic transmissionGO:00072683290.011
golgi to endosome transportGO:000689530.011
transmission of nerve impulseGO:0019226760.011
ras protein signal transductionGO:0007265770.011
glycoprotein metabolic processGO:00091001160.011
embryonic organ morphogenesisGO:00485622760.011
exocytosisGO:00068871210.011
negative regulation of cellular response to growth factor stimulusGO:0090288460.011
regulation of production of molecular mediator of immune responseGO:0002700650.011
carboxylic acid transportGO:00469421000.011
fat cell differentiationGO:00454441600.011
Mouse
protein processingGO:00164851630.011
nuclear transportGO:00511691390.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
regulation of establishment of protein localizationGO:00702011810.011
positive regulation of monocyte chemotaxisGO:009002620.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
response to transforming growth factor betaGO:0071559880.011
renal system developmentGO:00720012250.011
regulation of cellular response to growth factor stimulusGO:0090287820.011
epithelial cell proliferationGO:00506731740.011
regulation of t cell proliferationGO:0042129920.011
retrograde vesicle mediated transport golgi to erGO:000689010.011
response to extracellular stimulusGO:00099911270.011
amide transportGO:00428861380.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.011
positive regulation of cell migrationGO:00303351090.011
neuronal action potentialGO:0019228540.011
positive regulation of gtp catabolic processGO:0033126850.011
cellular response to hormone stimulusGO:00328701500.010
negative regulation of immune effector processGO:0002698550.010
positive regulation of nucleotide metabolic processGO:00459811140.010
regulation of multi organism processGO:00439001110.010
regulation of leukocyte differentiationGO:19021051590.010
peptide transportGO:00158331330.010
positive regulation of cellular catabolic processGO:00313311480.010
response to oxygen levelsGO:0070482620.010
fatty acid metabolic processGO:00066311210.010
localization within membraneGO:005166840.010
fatty acid alpha oxidationGO:000156120.010
apoptotic mitochondrial changesGO:0008637480.010
cation transmembrane transportGO:00986552660.010
mitochondrion organizationGO:00070051340.010
gtp catabolic processGO:00061841430.010

Insig2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
nervous system diseaseDOID:86300.025
disease of metabolismDOID:001466700.022
musculoskeletal system diseaseDOID:1700.015
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.011
eye diseaseDOID:561400.010