IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Lrrc57

leucine rich repeat containing 57

(Aliases: 2810002D13Rik,AA407405)

Entrez: 66606
Ensembl: ENSMUSG00000027286
UniProtKB: Q8JZX5

Process Predictions
Disease Predictions

Lrrc57 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cytoplasmic transport	GO:0016482	234	0.056
apoptotic signaling pathway	GO:0097190	306	0.043
protein catabolic process	GO:0030163	221	0.043
regulation of apoptotic signaling pathway	GO:2001233	197	0.041
protein modification by small protein conjugation or removal	GO:0070647	207	0.037
regulation of cellular amino acid metabolic process	GO:0006521	5	0.036
heterocycle catabolic process	GO:0046700	280	0.036
wnt signaling pathway	GO:0016055	188	0.036
regulation of protein localization	GO:0032880	231	0.035
intracellular protein transport	GO:0006886	204	0.034
membrane organization	GO:0061024	245	0.033
negative regulation of protein metabolic process	GO:0051248	282	0.033
nucleobase containing small molecule metabolic process	GO:0055086	352	0.032
dna metabolic process	GO:0006259	303	0.031
cellular amine metabolic process	GO:0044106	44	0.031
regulation of protein transport	GO:0051223	163	0.031
nucleotide metabolic process	GO:0009117	332	0.031
cellular amino acid metabolic process	GO:0006520	103	0.031
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.030
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.030
macromolecule catabolic process	GO:0009057	281	0.030
muscle cell differentiation	GO:0042692	261	0.029
purine ribonucleotide catabolic process	GO:0009154	208	0.029
purine containing compound metabolic process	GO:0072521	311	0.029
nucleoside triphosphate metabolic process	GO:0009141	230	0.028
glycosyl compound metabolic process	GO:1901657	246	0.028
positive regulation of apoptotic process	GO:0043065	217	0.028
muscle tissue development	GO:0060537	308	0.028
fat cell differentiation	GO:0045444	160	0.028
nucleoside phosphate metabolic process	GO:0006753	338	0.027
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.027
nucleoside metabolic process	GO:0009116	246	0.027
proteasomal protein catabolic process	GO:0010498	98	0.027
cation transport	GO:0006812	399	0.027
amine metabolic process	GO:0009308	45	0.026
modification dependent protein catabolic process	GO:0019941	133	0.026
modification dependent macromolecule catabolic process	GO:0043632	133	0.026
positive regulation of protein modification process	GO:0031401	299	0.026
aromatic compound catabolic process	GO:0019439	286	0.026
canonical wnt signaling pathway	GO:0060070	130	0.026
cellular ketone metabolic process	GO:0042180	84	0.025
regulation of transferase activity	GO:0051338	263	0.025
nitrogen compound transport	GO:0071705	271	0.025
regulation of intracellular protein transport	GO:0033157	82	0.025
vesicle localization	GO:0051648	86	0.025
positive regulation of programmed cell death	GO:0043068	218	0.025
posttranscriptional regulation of gene expression	GO:0010608	155	0.024
protein ubiquitination	GO:0016567	171	0.024
positive regulation of cellular amine metabolic process	GO:0033240	5	0.024
intrinsic apoptotic signaling pathway	GO:0097193	132	0.024
leukocyte differentiation	GO:0002521	342	0.024
striated muscle tissue development	GO:0014706	293	0.024
purine nucleotide metabolic process	GO:0006163	302	0.024
carbohydrate metabolic process	GO:0005975	230	0.023
regulation of organelle organization	GO:0033043	289	0.023
purine ribonucleotide metabolic process	GO:0009150	290	0.023
ribonucleoside catabolic process	GO:0042454	206	0.023
cellular macromolecule catabolic process	GO:0044265	206	0.023
endocytosis	GO:0006897	168	0.023
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.023
protein modification by small protein conjugation	GO:0032446	187	0.023
organic cyclic compound catabolic process	GO:1901361	295	0.023
ribose phosphate metabolic process	GO:0019693	291	0.023
purine ribonucleoside metabolic process	GO:0046128	241	0.022
negative regulation of cellular protein metabolic process	GO:0032269	247	0.022
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.022
positive regulation of cell death	GO:0010942	224	0.022
spermatogenesis	GO:0007283	284	0.022
protein localization to organelle	GO:0033365	185	0.022
regulation of intracellular transport	GO:0032386	159	0.021
vacuole organization	GO:0007033	38	0.021
purine ribonucleoside catabolic process	GO:0046130	205	0.021
nucleoside catabolic process	GO:0009164	206	0.021
negative regulation of cell proliferation	GO:0008285	296	0.021
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.021
regulation of cellular amine metabolic process	GO:0033238	20	0.021
peptidyl amino acid modification	GO:0018193	336	0.021
meiotic nuclear division	GO:0007126	115	0.020
skeletal muscle organ development	GO:0060538	163	0.020
organelle fission	GO:0048285	170	0.020
immune effector process	GO:0002252	321	0.020
endomembrane system organization	GO:0010256	147	0.020
homeostasis of number of cells	GO:0048872	210	0.020
regulation of cell cycle	GO:0051726	281	0.020
nucleoside triphosphate catabolic process	GO:0009143	205	0.020
purine nucleoside metabolic process	GO:0042278	241	0.020
divalent inorganic cation transport	GO:0072511	178	0.020
cellular homeostasis	GO:0019725	240	0.019
defense response to other organism	GO:0098542	197	0.019
regulation of establishment of protein localization	GO:0070201	181	0.019
regulation of cellular ketone metabolic process	GO:0010565	66	0.019
nuclear transport	GO:0051169	139	0.019
organic acid transport	GO:0015849	101	0.019
divalent metal ion transport	GO:0070838	172	0.019
ribonucleotide catabolic process	GO:0009261	208	0.019
g protein coupled receptor signaling pathway	GO:0007186	243	0.019
cellular protein catabolic process	GO:0044257	155	0.019
male gamete generation	GO:0048232	285	0.019
organelle localization	GO:0051640	179	0.019
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.018
cellular nitrogen compound catabolic process	GO:0044270	280	0.018
response to growth factor	GO:0070848	198	0.018
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.018
cellular response to dna damage stimulus	GO:0006974	207	0.018
purine nucleoside catabolic process	GO:0006152	205	0.018
regulation of secretion	GO:0051046	274	0.018
nucleoside phosphate catabolic process	GO:1901292	222	0.018
ribonucleoside metabolic process	GO:0009119	245	0.018
meiotic cell cycle	GO:0051321	122	0.018
nucleotide catabolic process	GO:0009166	217	0.018
myeloid cell differentiation	GO:0030099	233	0.018
protein import into nucleus	GO:0006606	95	0.018
dephosphorylation	GO:0016311	129	0.018
cell type specific apoptotic process	GO:0097285	268	0.018
negative regulation of protein modification process	GO:0031400	163	0.017
protein targeting	GO:0006605	143	0.017
protein import	GO:0017038	101	0.017
mitotic cell cycle	GO:0000278	195	0.017
regulation of kinase activity	GO:0043549	249	0.017
regulation of cytoplasmic transport	GO:1903649	112	0.017
regulation of cell activation	GO:0050865	289	0.017
defense response to bacterium	GO:0042742	119	0.017
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.017
negative regulation of phosphate metabolic process	GO:0045936	184	0.017
negative regulation of intracellular signal transduction	GO:1902532	167	0.016
negative regulation of molecular function	GO:0044092	258	0.016
gtp metabolic process	GO:0046039	144	0.016
regulation of secretion by cell	GO:1903530	249	0.016
cation homeostasis	GO:0055080	212	0.016
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.016
response to nutrient levels	GO:0031667	109	0.016
negative regulation of cellular component organization	GO:0051129	194	0.016
nucleocytoplasmic transport	GO:0006913	139	0.016
organelle assembly	GO:0070925	177	0.016
glycosyl compound catabolic process	GO:1901658	206	0.016
sequestering of calcium ion	GO:0051208	18	0.016
carbohydrate derivative biosynthetic process	GO:1901137	183	0.016
positive regulation of cell development	GO:0010720	237	0.016
response to oxidative stress	GO:0006979	123	0.016
negative regulation of kinase activity	GO:0033673	81	0.016
purine containing compound catabolic process	GO:0072523	213	0.016
carbohydrate derivative catabolic process	GO:1901136	231	0.016
cellular chemical homeostasis	GO:0055082	215	0.016
spermatid development	GO:0007286	108	0.016
organonitrogen compound catabolic process	GO:1901565	264	0.016
sequestering of metal ion	GO:0051238	19	0.016
p38mapk cascade	GO:0038066	4	0.016
establishment of vesicle localization	GO:0051650	81	0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.016
ribonucleotide metabolic process	GO:0009259	291	0.016
cation transmembrane transport	GO:0098655	266	0.016
response to radiation	GO:0009314	165	0.016
regulation of mapk cascade	GO:0043408	248	0.015
amide transport	GO:0042886	138	0.015
positive regulation of intracellular transport	GO:0032388	70	0.015
regulation of nucleotide catabolic process	GO:0030811	122	0.015
organophosphate catabolic process	GO:0046434	232	0.015
purine nucleotide catabolic process	GO:0006195	211	0.015
response to organonitrogen compound	GO:0010243	246	0.015
t cell activation	GO:0042110	289	0.015
carboxylic acid transport	GO:0046942	100	0.015
regulation of wnt signaling pathway	GO:0030111	123	0.015
transmembrane transport	GO:0055085	412	0.015
intrinsic apoptotic signaling pathway in response to dna damage	GO:0008630	57	0.015
muscle fiber development	GO:0048747	76	0.015
engulfment of apoptotic cell	GO:0043652	3	0.015
synaptic transmission	GO:0007268	329	0.015
regulation of cytokine production	GO:0001817	266	0.015
regulation of homeostatic process	GO:0032844	182	0.015
negative regulation of cell cycle	GO:0045786	123	0.015
regulation of membrane potential	GO:0042391	192	0.015
reactive oxygen species metabolic process	GO:0072593	84	0.015
regulation of nucleotide metabolic process	GO:0006140	169	0.015
regulation of vesicle mediated transport	GO:0060627	139	0.015
metal ion homeostasis	GO:0055065	189	0.014
multicellular organismal signaling	GO:0035637	91	0.014
regulation of cellular catabolic process	GO:0031329	242	0.014
organonitrogen compound biosynthetic process	GO:1901566	192	0.014
anatomical structure homeostasis	GO:0060249	145	0.014
single organism nuclear import	GO:1902593	95	0.014
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.014
regulation of purine nucleotide metabolic process	GO:1900542	169	0.014
dna endoreduplication	GO:0042023	4	0.014
organophosphate biosynthetic process	GO:0090407	122	0.014
regulation of cell projection organization	GO:0031344	206	0.014
negative regulation of immune system process	GO:0002683	209	0.014
establishment of organelle localization	GO:0051656	122	0.014
guanosine containing compound catabolic process	GO:1901069	144	0.014
gtp catabolic process	GO:0006184	143	0.014
regulation of hormone levels	GO:0010817	211	0.014
substantia nigra development	GO:0021762	2	0.014
protein maturation	GO:0051604	176	0.014
myeloid leukocyte differentiation	GO:0002573	119	0.014
cellular response to extracellular stimulus	GO:0031668	81	0.014
protein localization to nucleus	GO:0034504	121	0.013
ubiquitin dependent protein catabolic process	GO:0006511	129	0.013
positive regulation of protein transport	GO:0051222	93	0.013
regulation of protein kinase activity	GO:0045859	232	0.013
lymphocyte differentiation	GO:0030098	242	0.013
positive regulation of protein phosphorylation	GO:0001934	242	0.013
gene silencing	GO:0016458	38	0.013
methylation	GO:0032259	134	0.013
response to light stimulus	GO:0009416	135	0.013
regulation of defense response	GO:0031347	233	0.013
histone modification	GO:0016570	159	0.013
germ cell development	GO:0007281	185	0.013
nuclear division	GO:0000280	158	0.013
mapk cascade	GO:0000165	281	0.013
phospholipid metabolic process	GO:0006644	87	0.013
embryonic organ morphogenesis	GO:0048562	276	0.013
cellular ion homeostasis	GO:0006873	165	0.013
vesicle organization	GO:0016050	60	0.013
regulation of protein serine threonine kinase activity	GO:0071900	157	0.013
establishment of melanosome localization	GO:0032401	11	0.013
regulation of neuron differentiation	GO:0045664	281	0.013
cellular protein complex assembly	GO:0043623	116	0.013
dna repair	GO:0006281	107	0.013
positive regulation of secretion	GO:0051047	130	0.013
early endosome to late endosome transport	GO:0045022	2	0.013
transmission of nerve impulse	GO:0019226	76	0.013
organic anion transport	GO:0015711	137	0.013
exocytosis	GO:0006887	121	0.013
regulation of cell migration	GO:0030334	219	0.012
regionalization	GO:0003002	337	0.012
neuronal action potential	GO:0019228	54	0.012
cognition	GO:0050890	149	0.012
establishment of protein localization to organelle	GO:0072594	118	0.012
regulation of hydrolase activity	GO:0051336	246	0.012
sensory perception	GO:0007600	245	0.012
nuclear import	GO:0051170	95	0.012
negative regulation of phosphorylation	GO:0042326	166	0.012
glucose homeostasis	GO:0042593	128	0.012
regulation of cellular response to stress	GO:0080135	159	0.012
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.012
rna processing	GO:0006396	105	0.012
anion transport	GO:0006820	177	0.012
regulation of engulfment of apoptotic cell	GO:1901074	2	0.012
regulation of cellular component biogenesis	GO:0044087	181	0.012
negative regulation of transferase activity	GO:0051348	85	0.012
guanosine containing compound metabolic process	GO:1901068	144	0.012
organic hydroxy compound metabolic process	GO:1901615	203	0.012
camera type eye development	GO:0043010	266	0.012
regulation of canonical wnt signaling pathway	GO:0060828	82	0.012
plasma membrane organization	GO:0007009	90	0.011
cellular component assembly involved in morphogenesis	GO:0010927	139	0.011
skeletal system development	GO:0001501	356	0.011
cytokine production	GO:0001816	319	0.011
inorganic ion transmembrane transport	GO:0098660	234	0.011
negative regulation of phosphorus metabolic process	GO:0010563	184	0.011
compound eye development	GO:0048749	1	0.011
regulation of protein localization to nucleus	GO:1900180	60	0.011
glycerolipid metabolic process	GO:0046486	122	0.011
response to extracellular stimulus	GO:0009991	127	0.011
angiogenesis	GO:0001525	201	0.011
cellular response to external stimulus	GO:0071496	88	0.011
multicellular organism growth	GO:0035264	161	0.011
membrane fusion	GO:0061025	38	0.011
regulation of lymphocyte activation	GO:0051249	240	0.011
cellular response to cytokine stimulus	GO:0071345	189	0.011
regulation of proteolysis	GO:0030162	164	0.011
cellular metal ion homeostasis	GO:0006875	151	0.011
smoothened signaling pathway	GO:0007224	105	0.011
ossification	GO:0001503	216	0.011
hematopoietic progenitor cell differentiation	GO:0002244	143	0.011
g1 s transition of mitotic cell cycle	GO:0000082	57	0.011
myotube differentiation	GO:0014902	105	0.011
meiotic cell cycle process	GO:1903046	77	0.011
positive regulation of hydrolase activity	GO:0051345	148	0.011
regulation of cell cycle process	GO:0010564	160	0.011
regulation of nucleoside metabolic process	GO:0009118	130	0.011
regulation of ion transport	GO:0043269	215	0.011
covalent chromatin modification	GO:0016569	163	0.011
i kappab kinase nf kappab signaling	GO:0007249	85	0.011
calcium ion transport	GO:0006816	159	0.011
spermatid differentiation	GO:0048515	115	0.011
innate immune response	GO:0045087	157	0.011
regulation of purine nucleotide catabolic process	GO:0033121	122	0.011
myotube cell development	GO:0014904	60	0.011
adult behavior	GO:0030534	135	0.010
muscle cell development	GO:0055001	133	0.010
microtubule based process	GO:0007017	236	0.010
response to starvation	GO:0042594	65	0.010
response to molecule of bacterial origin	GO:0002237	143	0.010
protein lipidation	GO:0006497	28	0.010
regulation of striated muscle cell differentiation	GO:0051153	81	0.010
response to acid chemical	GO:0001101	111	0.010
cellular response to acid chemical	GO:0071229	68	0.010
regulation of system process	GO:0044057	200	0.010
negative regulation of cell development	GO:0010721	169	0.010
stem cell maintenance	GO:0019827	130	0.010
negative regulation of cellular amine metabolic process	GO:0033239	1	0.010
protein localization to membrane	GO:0072657	108	0.010
positive regulation of cell activation	GO:0050867	158	0.010
striated muscle cell development	GO:0055002	125	0.010
regulation of protein targeting	GO:1903533	61	0.010
response to inorganic substance	GO:0010035	96	0.010
negative regulation of wnt signaling pathway	GO:0030178	73	0.010
synapsis	GO:0007129	34	0.010
multi multicellular organism process	GO:0044706	109	0.010
cellular response to growth factor stimulus	GO:0071363	197	0.010
small gtpase mediated signal transduction	GO:0007264	97	0.010
blood circulation	GO:0008015	195	0.010
translation	GO:0006412	93	0.010

Lrrc57 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.030
nervous system disease	DOID:863	0.030
musculoskeletal system disease	DOID:17	0.016
sensory system disease	DOID:0050155	0.013
eye and adnexa disease	DOID:1492	0.013
eye disease	DOID:5614	0.013
neurodegenerative disease	DOID:1289	0.013
central nervous system disease	DOID:331	0.013
disease of cellular proliferation	DOID:14566	0.011
retinal disease	DOID:5679	0.011

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