Mus musculus

62 known processes

Hsd17b4

hydroxysteroid (17-beta) dehydrogenase 4

(Aliases: 17-beta-HSD,MPF-2,perMFE-2,MFE-2,Mfp-2,MFP2,4,DBP,17[b]-HSD)

Hsd17b4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small molecule catabolic processGO:0044282710.985
monocarboxylic acid catabolic processGO:0072329270.950
organic acid catabolic processGO:0016054510.942
lipid modificationGO:0030258650.935
fatty acid oxidationGO:0019395280.891
lipid oxidationGO:0034440290.887
cellular lipid catabolic processGO:0044242520.864
fatty acid catabolic processGO:0009062250.858
lipid catabolic processGO:0016042690.847
carboxylic acid catabolic processGO:0046395510.833
monocarboxylic acid metabolic processGO:00327871910.792
cellular lipid metabolic processGO:00442553230.785
fatty acid beta oxidationGO:0006635160.740
fatty acid metabolic processGO:00066311210.721
thioester metabolic processGO:0035383190.630
Human
oxidation reduction processGO:00551143420.530
organic hydroxy compound metabolic processGO:19016152030.443
cellular ketone metabolic processGO:0042180840.419
very long chain fatty acid catabolic processGO:004276020.409
carnitine metabolic processGO:000943770.329
peroxisome organizationGO:000703170.309
small molecule biosynthetic processGO:00442831320.284
alcohol metabolic processGO:00060661160.254
acyl coa metabolic processGO:0006637190.242
Human
cellular amino acid metabolic processGO:00065201030.214
lipid localizationGO:00108761260.192
Worm
acylglycerol metabolic processGO:0006639550.156
carboxylic acid biosynthetic processGO:0046394860.151
regulation of cellular ketone metabolic processGO:0010565660.145
protein homooligomerizationGO:0051260430.135
steroid metabolic processGO:00082021190.123
Human
cellular amine metabolic processGO:0044106440.120
amino acid betaine metabolic processGO:000657770.113
protein oligomerizationGO:0051259670.112
very long chain fatty acid metabolic processGO:000003880.103
lipid biosynthetic processGO:00086101790.102
lipid transportGO:0006869980.096
sterol metabolic processGO:0016125580.093
membrane organizationGO:00610242450.088
cellular aldehyde metabolic processGO:0006081120.084
cofactor metabolic processGO:0051186800.083
Human
fatty acid alpha oxidationGO:000156120.083
coenzyme metabolic processGO:0006732520.083
Human
aldehyde catabolic processGO:004618540.072
organic cyclic compound catabolic processGO:19013612950.069
medium chain fatty acid metabolic processGO:005179110.068
regulation of hormone levelsGO:00108172110.067
Human
nucleobase containing small molecule metabolic processGO:00550863520.065
organonitrogen compound catabolic processGO:19015652640.064
maintenance of locationGO:0051235890.063
Worm
amine metabolic processGO:0009308450.063
anion transportGO:00068201770.062
ketone catabolic processGO:004218230.060
response to organic cyclic compoundGO:00140701980.060
regulation of cellular amino acid metabolic processGO:000652150.059
alpha amino acid biosynthetic processGO:1901607150.053
organic acid biosynthetic processGO:0016053860.052
cellular modified amino acid metabolic processGO:0006575630.051
glycerolipid metabolic processGO:00464861220.051
organic anion transportGO:00157111370.049
protein tetramerizationGO:0051262230.048
organic hydroxy compound biosynthetic processGO:1901617770.048
nucleoside phosphate metabolic processGO:00067533380.047
organonitrogen compound biosynthetic processGO:19015661920.047
defense response to other organismGO:00985421970.047
Worm
regulation of cellular catabolic processGO:00313292420.046
progesterone biosynthetic processGO:000670110.044
endomembrane system organizationGO:00102561470.044
cellular amino acid catabolic processGO:0009063250.043
hepaticobiliary system developmentGO:0061008670.042
triglyceride metabolic processGO:0006641510.042
protein localization to plasma membraneGO:0072659570.042
ribonucleoside triphosphate metabolic processGO:00091992200.041
protein localization to membraneGO:00726571080.041
diterpenoid metabolic processGO:0016101240.039
isoprenoid metabolic processGO:0006720290.038
liver developmentGO:0001889660.038
glycerophospholipid metabolic processGO:0006650710.038
ribose phosphate metabolic processGO:00196932910.038
generation of precursor metabolites and energyGO:00060911030.037
regulation of intracellular transportGO:00323861590.036
glycosyl compound metabolic processGO:19016572460.035
regulation of removal of superoxide radicalsGO:200012140.035
regulation of cellular amine metabolic processGO:0033238200.035
positive regulation of cellular amino acid metabolic processGO:004576430.035
intracellular lipid transportGO:003236530.035
purine ribonucleotide metabolic processGO:00091502900.035
positive regulation of cellular amine metabolic processGO:003324050.034
homeostasis of number of cellsGO:00488722100.033
purine nucleoside metabolic processGO:00422782410.033
energy derivation by oxidation of organic compoundsGO:0015980770.031
cytoplasmic transportGO:00164822340.030
microtubule based processGO:00070172360.030
response to copper ionGO:004668830.030
ribonucleotide metabolic processGO:00092592910.029
nucleoside metabolic processGO:00091162460.029
alcohol biosynthetic processGO:0046165430.029
response to steroid hormoneGO:0048545560.029
alpha amino acid metabolic processGO:1901605590.029
positive regulation of protein modification processGO:00314012990.029
nucleotide metabolic processGO:00091173320.029
retinoid metabolic processGO:0001523240.029
glucose metabolic processGO:0006006920.028
aromatic compound catabolic processGO:00194392860.028
fatty acid transmembrane transportGO:190200110.028
protein import into peroxisome matrixGO:001655830.028
neutral lipid metabolic processGO:0006638570.028
gland developmentGO:00487323300.027
cellular amino acid biosynthetic processGO:0008652220.027
protein targeting to peroxisomeGO:000662540.027
regulation of protein localizationGO:00328802310.026
establishment of protein localization to peroxisomeGO:007266340.026
regulation of apoptotic signaling pathwayGO:20012331970.026
heterocycle catabolic processGO:00467002800.026
monocarboxylic acid biosynthetic processGO:0072330610.026
c21 steroid hormone biosynthetic processGO:000670030.026
muscle cell differentiationGO:00426922610.025
protein localization to organelleGO:00333651850.025
organophosphate catabolic processGO:00464342320.025
synaptic transmissionGO:00072683290.025
coenzyme biosynthetic processGO:0009108230.025
ribonucleotide catabolic processGO:00092612080.024
glutamine family amino acid biosynthetic processGO:000908420.024
terpenoid metabolic processGO:0006721250.023
regulation of lipid metabolic processGO:00192161180.023
regulation of secretion by cellGO:19035302490.023
positive regulation of reactive oxygen species metabolic processGO:2000379110.023
response to oxidative stressGO:00069791230.023
nitrogen compound transportGO:00717052710.023
regulation of neurotransmitter levelsGO:0001505870.022
primary alcohol metabolic processGO:0034308110.022
cellular nitrogen compound catabolic processGO:00442702800.022
monosaccharide biosynthetic processGO:0046364440.022
response to drugGO:0042493750.022
heart morphogenesisGO:00030071780.022
intracellular protein transportGO:00068862040.022
nuclear transportGO:00511691390.022
gonad developmentGO:00084061410.022
organic hydroxy compound transportGO:0015850930.021
nucleocytoplasmic transportGO:00069131390.021
branched chain amino acid catabolic processGO:000908320.021
regulation of kinase activityGO:00435492490.021
lipid storageGO:0019915360.021
Worm
peptidyl amino acid modificationGO:00181933360.021
purine nucleotide metabolic processGO:00061633020.021
carbohydrate metabolic processGO:00059752300.021
response to inorganic substanceGO:0010035960.021
response to organonitrogen compoundGO:00102432460.021
purine ribonucleoside metabolic processGO:00461282410.020
apoptotic signaling pathwayGO:00971903060.020
ion transmembrane transportGO:00342203610.020
regulation of fatty acid beta oxidationGO:003199810.020
skin developmentGO:00435882200.020
response to oxygen radicalGO:0000305160.020
response to acid chemicalGO:00011011110.020
leukocyte differentiationGO:00025213420.020
regulation of mitochondrion organizationGO:0010821270.020
nucleoside triphosphate metabolic processGO:00091412300.019
response to nutrient levelsGO:00316671090.019
carbohydrate derivative catabolic processGO:19011362310.019
ossificationGO:00015032160.019
Human
regulation of response to woundingGO:19030341890.019
negative regulation of molecular functionGO:00440922580.019
succinyl coa metabolic processGO:000610410.019
negative regulation of immune system processGO:00026832090.019
glutamate biosynthetic processGO:000653720.019
cellular homeostasisGO:00197252400.018
phospholipid metabolic processGO:0006644870.018
tricarboxylic acid metabolic processGO:007235050.018
plasma membrane organizationGO:0007009900.018
regulation of interleukin 8 productionGO:003267730.018
cytokine productionGO:00018163190.018
neuron apoptotic processGO:00514021420.018
purine nucleoside triphosphate metabolic processGO:00091442260.018
purine nucleotide catabolic processGO:00061952110.018
regulation of transferase activityGO:00513382630.017
nucleoside phosphate catabolic processGO:19012922220.017
renal system developmentGO:00720012250.017
positive regulation of cholesterol transportGO:003237690.017
regulation of cell activationGO:00508652890.017
hormone metabolic processGO:0042445860.017
Human
reactive oxygen species metabolic processGO:0072593840.017
ribonucleoside metabolic processGO:00091192450.017
innate immune responseGO:00450871570.017
Worm
sulfur compound metabolic processGO:00067901000.017
Human
response to starvationGO:0042594650.017
multicellular organismal signalingGO:0035637910.017
nucleotide catabolic processGO:00091662170.017
striated muscle tissue developmentGO:00147062930.017
interleukin 8 productionGO:003263740.017
cellular macromolecule catabolic processGO:00442652060.017
purine ribonucleoside monophosphate metabolic processGO:0009167800.016
glycerol ether metabolic processGO:000666220.016
positive regulation of intracellular transportGO:0032388700.016
action potentialGO:0001508780.016
regulation of cytokine productionGO:00018172660.016
reactive oxygen species biosynthetic processGO:190340980.016
cellular chemical homeostasisGO:00550822150.016
protein localization to nucleusGO:00345041210.016
positive regulation of lipid metabolic processGO:0045834400.016
purine containing compound catabolic processGO:00725232130.016
regulation of nucleotide metabolic processGO:00061401690.016
immune effector processGO:00022523210.016
cholesterol metabolic processGO:0008203560.016
negative regulation of intracellular signal transductionGO:19025321670.016
t cell activationGO:00421102890.015
response to lipopolysaccharideGO:00324961280.015
myeloid cell differentiationGO:00300992330.015
positive regulation of interleukin 8 productionGO:003275720.015
progesterone metabolic processGO:004244840.015
forebrain developmentGO:00309003020.015
response to reactive oxygen speciesGO:0000302560.015
positive regulation of secretion by cellGO:19035321140.015
neuron deathGO:00709971540.015
organophosphate biosynthetic processGO:00904071220.015
sterol transportGO:0015918380.015
protein processingGO:00164851630.015
adult behaviorGO:00305341350.015
regulation of protein transportGO:00512231630.015
regulation of protein kinase activityGO:00458592320.015
response to extracellular stimulusGO:00099911270.015
defense response to bacteriumGO:00427421190.015
Worm
peroxisomal transportGO:004357440.015
establishment of protein localization to vacuoleGO:007266640.015
neuronal action potentialGO:0019228540.015
macromolecule catabolic processGO:00090572810.015
purine ribonucleoside catabolic processGO:00461302050.015
nucleoside monophosphate metabolic processGO:0009123850.015
lipid homeostasisGO:0055088630.014
response to epidermal growth factorGO:007084940.014
regulation of membrane potentialGO:00423911920.014
positive regulation of cell activationGO:00508671580.014
negative regulation of cellular amine metabolic processGO:003323910.014
citrate metabolic processGO:000610130.014
cellular response to molecule of bacterial originGO:0071219830.014
response to molecule of bacterial originGO:00022371430.014
nucleoside catabolic processGO:00091642060.014
purine ribonucleotide catabolic processGO:00091542080.014
synapse organizationGO:00508081250.014
positive regulation of steroid biosynthetic processGO:001089340.014
locomotory behaviorGO:00076261950.014
hair follicle developmentGO:0001942850.014
telencephalon developmentGO:00215371860.014
positive regulation of protein phosphorylationGO:00019342420.014
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.014
reactive nitrogen species metabolic processGO:200105700.014
mapk cascadeGO:00001652810.014
transmission of nerve impulseGO:0019226760.014
ribonucleoside triphosphate catabolic processGO:00092031990.014
purine nucleoside catabolic processGO:00061522050.014
tissue homeostasisGO:00018941150.014
small gtpase mediated signal transductionGO:0007264970.014
regulation of secretionGO:00510462740.014
regulation of reactive oxygen species metabolic processGO:2000377400.014
atp metabolic processGO:0046034750.014
sensory perceptionGO:00076002450.013
regulation of vesicle mediated transportGO:00606271390.013
muscle tissue developmentGO:00605373080.013
hexose metabolic processGO:0019318980.013
positive regulation of secretionGO:00510471300.013
negative regulation of protein metabolic processGO:00512482820.013
t cell differentiationGO:00302171740.013
myeloid leukocyte differentiationGO:00025731190.013
dicarboxylic acid metabolic processGO:0043648180.013
protein localization to peroxisomeGO:007266240.013
regulation of lymphocyte activationGO:00512492400.013
purine ribonucleoside triphosphate metabolic processGO:00092052200.013
steroid biosynthetic processGO:0006694470.013
glycogen metabolic processGO:0005977320.013
negative regulation of cellular protein metabolic processGO:00322692470.013
gluconeogenesisGO:0006094390.013
positive regulation of cell deathGO:00109422240.013
endocytosisGO:00068971680.013
regulation of establishment of protein localizationGO:00702011810.013
energy reserve metabolic processGO:0006112390.013
negative regulation of phosphate metabolic processGO:00459361840.013
cellular metal ion homeostasisGO:00068751510.013
ensheathment of neuronsGO:0007272760.013
negative regulation of protein modification processGO:00314001630.013
urogenital system developmentGO:00016552610.013
regulation of reactive oxygen species biosynthetic processGO:190342620.013
spermatogenesisGO:00072832840.013
cell type specific apoptotic processGO:00972852680.013
cellularizationGO:000734910.013
negative regulation of protein phosphorylationGO:00019331260.013
hematopoietic progenitor cell differentiationGO:00022441430.013
purine containing compound metabolic processGO:00725213110.013
regulation of steroid metabolic processGO:0019218390.013
positive regulation of lymphocyte activationGO:00512511400.013
phospholipid transportGO:0015914210.012
regulation of synaptic growth at neuromuscular junctionGO:000858240.012
cellular response to hormone stimulusGO:00328701500.012
regulation of defense responseGO:00313472330.012
development of primary male sexual characteristicsGO:0046546880.012
ribonucleoside catabolic processGO:00424542060.012
glycogen biosynthetic processGO:0005978140.012
cellular response to organonitrogen compoundGO:00714171450.012
carbohydrate biosynthetic processGO:0016051740.012
epithelial cell developmentGO:00020641590.012
circulatory system processGO:00030131970.012
microtubule cytoskeleton organizationGO:00002261570.012
cellular carbohydrate metabolic processGO:00442621190.012
response to peptideGO:19016521360.012
purine nucleoside monophosphate metabolic processGO:0009126810.012
response to light stimulusGO:00094161350.012
negative regulation of phosphorylationGO:00423261660.012
negative regulation of apoptotic signaling pathwayGO:20012341040.012
regulation of cytoplasmic transportGO:19036491120.012
response to growth factorGO:00708481980.012
cardiac muscle tissue developmentGO:00487381300.012
regulation of t cell activationGO:00508631700.012
cofactor biosynthetic processGO:0051188410.011
response to testosteroneGO:003357430.011
regulation of cellular response to stressGO:00801351590.011
axonogenesisGO:00074092740.011
cellular respirationGO:0045333380.011
male gamete generationGO:00482322850.011
cellular ion homeostasisGO:00068731650.011
protein homotetramerizationGO:0051289120.011
nucleoside triphosphate catabolic processGO:00091432050.011
molting cycleGO:0042303900.011
dna metabolic processGO:00062593030.011
cholesterol transportGO:0030301380.011
cellular response to oxidative stressGO:0034599760.011
kidney developmentGO:00018222130.011
cellular response to superoxideGO:0071451140.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
neuron migrationGO:00017641220.011
metal ion homeostasisGO:00550651890.011
negative regulation of cellular amino acid metabolic processGO:004576300.011
response to oxygen levelsGO:0070482620.011
removal of superoxide radicalsGO:0019430120.011
hair cycleGO:0042633900.011
glycosyl compound catabolic processGO:19016582060.011
nephron developmentGO:00720061090.011
immune response regulating signaling pathwayGO:00027641250.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
protein secretionGO:00093061110.011
regulation of homeostatic processGO:00328441820.011
substantia nigra developmentGO:002176220.011
cellular response to lipidGO:00713961450.011
g protein coupled receptor signaling pathwayGO:00071862430.011
regulation of body fluid levelsGO:00508781620.011
exocytosisGO:00068871210.011
camera type eye developmentGO:00430102660.011
t cell proliferationGO:00420981200.011
multicellular organism growthGO:00352641610.011
sensory organ morphogenesisGO:00905962420.011
male sex differentiationGO:00466611090.011
immune response activating signal transductionGO:00027571160.010
positive regulation of glycolytic processGO:004582140.010
organic acid transportGO:00158491010.010
response to metal ionGO:0010038470.010
cellular protein complex assemblyGO:00436231160.010
multicellular organismal homeostasisGO:00488711640.010
nuclear exportGO:0051168340.010
regulation of fatty acid metabolic processGO:0019217280.010
monosaccharide metabolic processGO:00059961060.010
anion transmembrane transportGO:0098656710.010
calcium mediated signaling using intracellular calcium sourceGO:003558430.010
posttranscriptional regulation of gene expressionGO:00106081550.010
regulation of organelle organizationGO:00330432890.010
hexose biosynthetic processGO:0019319390.010
alpha amino acid catabolic processGO:1901606180.010
intrinsic apoptotic signaling pathwayGO:00971931320.010
regulation of lymphocyte proliferationGO:00506701170.010

Hsd17b4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.414
inherited metabolic disorderDOID:65500.067
nervous system diseaseDOID:86300.036
disease of anatomical entityDOID:700.036
carbohydrate metabolic disorderDOID:297800.035
hyperinsulinemic hypoglycemiaDOID:1331700.034
central nervous system diseaseDOID:33100.012
sensory system diseaseDOID:005015500.012
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011