Mus musculus

3 known processes

Gpnmb

glycoprotein (transmembrane) nmb

(Aliases: DC-HIL,Dchil,ipd)

Gpnmb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation transportGO:00068123990.116
regulation of response to woundingGO:19030341890.079
immune effector processGO:00022523210.079
regulation of cell activationGO:00508652890.076
regulation of defense responseGO:00313472330.062
regulation of cytokine productionGO:00018172660.059
cytokine productionGO:00018163190.059
transmembrane transportGO:00550854120.059
cellular lipid metabolic processGO:00442553230.058
cellular ketone metabolic processGO:0042180840.057
cellular amino acid metabolic processGO:00065201030.056
regulation of inflammatory responseGO:00507271470.055
regulation of cellular ketone metabolic processGO:0010565660.054
inflammatory responseGO:00069542440.053
negative regulation of cellular protein metabolic processGO:00322692470.050
regulation of organelle organizationGO:00330432890.050
fatty acid metabolic processGO:00066311210.050
positive regulation of defense responseGO:00313491240.047
nucleobase containing small molecule metabolic processGO:00550863520.047
monocarboxylic acid metabolic processGO:00327871910.046
glycosyl compound metabolic processGO:19016572460.043
membrane organizationGO:00610242450.041
anion transportGO:00068201770.041
purine containing compound metabolic processGO:00725213110.041
negative regulation of immune system processGO:00026832090.040
positive regulation of nervous system developmentGO:00519622210.040
regulation of intracellular transportGO:00323861590.039
negative regulation of cell proliferationGO:00082852960.039
detection of molecule of bacterial originGO:003249020.039
ribonucleoside metabolic processGO:00091192450.039
regulation of establishment of protein localizationGO:00702011810.039
nucleoside phosphate metabolic processGO:00067533380.038
amine metabolic processGO:0009308450.038
ion transmembrane transportGO:00342203610.037
organic anion transportGO:00157111370.037
connective tissue developmentGO:00614481790.037
muscle cell differentiationGO:00426922610.037
response to inorganic substanceGO:0010035960.036
leukocyte migrationGO:00509001240.035
regulation of cellular amine metabolic processGO:0033238200.035
cellular amine metabolic processGO:0044106440.035
cell chemotaxisGO:0060326810.035
organic hydroxy compound metabolic processGO:19016152030.035
Mouse
response to organonitrogen compoundGO:00102432460.034
reactive oxygen species metabolic processGO:0072593840.034
lipid biosynthetic processGO:00086101790.034
regulation of protein transportGO:00512231630.034
purine ribonucleoside metabolic processGO:00461282410.033
regulation of secretion by cellGO:19035302490.033
cytokine secretionGO:0050663720.033
ribose phosphate metabolic processGO:00196932910.033
ribonucleotide catabolic processGO:00092612080.033
purine nucleotide metabolic processGO:00061633020.033
regulation of vesicle mediated transportGO:00606271390.033
leukocyte mediated immunityGO:00024431740.033
cation homeostasisGO:00550802120.032
g protein coupled receptor signaling pathwayGO:00071862430.032
defense response to other organismGO:00985421970.032
rho protein signal transductionGO:0007266320.032
regulation of cellular amino acid metabolic processGO:000652150.031
positive regulation of programmed cell deathGO:00430682180.031
positive regulation of cytokine productionGO:00018191740.030
organic cyclic compound catabolic processGO:19013612950.030
regulation of secretionGO:00510462740.030
oxidation reduction processGO:00551143420.030
regulation of leukocyte mediated immunityGO:00027031040.030
regulation of kinase activityGO:00435492490.030
positive regulation of cell developmentGO:00107202370.030
ossificationGO:00015032160.029
forebrain developmentGO:00309003020.029
cell adhesionGO:00071553290.029
nucleoside phosphate catabolic processGO:19012922220.029
chemotaxisGO:00069352470.029
macromolecule catabolic processGO:00090572810.029
vesicle organizationGO:0016050600.029
response to lipopolysaccharideGO:00324961280.029
regulation of protein secretionGO:0050708820.029
detection of stimulusGO:0051606840.029
response to molecule of bacterial originGO:00022371430.028
t cell activationGO:00421102890.028
purine ribonucleotide metabolic processGO:00091502900.028
carbohydrate derivative catabolic processGO:19011362310.028
positive regulation of cellular amine metabolic processGO:003324050.028
nucleoside metabolic processGO:00091162460.028
positive regulation of secretion by cellGO:19035321140.028
positive regulation of protein modification processGO:00314012990.028
placenta developmentGO:00018901400.027
metal ion homeostasisGO:00550651890.027
striated muscle tissue developmentGO:00147062930.027
hematopoietic progenitor cell differentiationGO:00022441430.027
ribonucleoside catabolic processGO:00424542060.027
nucleoside catabolic processGO:00091642060.027
protein processingGO:00164851630.027
regulation of lymphocyte activationGO:00512492400.027
aromatic compound catabolic processGO:00194392860.027
negative regulation of intracellular signal transductionGO:19025321670.026
positive regulation of apoptotic processGO:00430652170.026
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.026
purine ribonucleotide catabolic processGO:00091542080.026
innate immune responseGO:00450871570.026
regulation of body fluid levelsGO:00508781620.026
ketone body metabolic processGO:190222430.026
spermatogenesisGO:00072832840.026
nitrogen compound transportGO:00717052710.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
positive regulation of response to woundingGO:1903036660.025
protein catabolic processGO:00301632210.025
response to organic cyclic compoundGO:00140701980.025
skeletal system developmentGO:00015013560.025
ribonucleoside triphosphate catabolic processGO:00092031990.025
pigment biosynthetic processGO:0046148260.025
Mouse
lymphocyte differentiationGO:00300982420.025
protein maturationGO:00516041760.024
fat cell differentiationGO:00454441600.024
ribonucleotide metabolic processGO:00092592910.024
purine nucleoside metabolic processGO:00422782410.024
glycosyl compound catabolic processGO:19016582060.024
organic acid transportGO:00158491010.024
regulation of ion transportGO:00432692150.024
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.024
leukocyte differentiationGO:00025213420.024
purine containing compound catabolic processGO:00725232130.024
negative regulation of cellular amine metabolic processGO:003323910.024
muscle tissue developmentGO:00605373080.024
purine nucleoside triphosphate metabolic processGO:00091442260.023
purine ribonucleoside triphosphate metabolic processGO:00092052200.023
heterocycle catabolic processGO:00467002800.023
cellular response to organonitrogen compoundGO:00714171450.023
multicellular organismal homeostasisGO:00488711640.023
positive regulation of homeostatic processGO:0032846640.023
regulation of protein localizationGO:00328802310.023
blood vessel morphogenesisGO:00485142850.023
positive regulation of inflammatory responseGO:0050729470.023
cellular metal ion homeostasisGO:00068751510.023
calcium ion transportGO:00068161590.023
sequestering of calcium ionGO:0051208180.023
regulation of cytokine secretionGO:0050707610.023
purine nucleoside triphosphate catabolic processGO:00091462030.022
cellular nitrogen compound catabolic processGO:00442702800.022
small molecule biosynthetic processGO:00442831320.022
organonitrogen compound catabolic processGO:19015652640.022
regulation of cell motilityGO:20001452360.022
gland developmentGO:00487323300.022
inorganic cation transmembrane transportGO:00986622070.022
cellular response to cytokine stimulusGO:00713451890.022
ras protein signal transductionGO:0007265770.022
cation transmembrane transportGO:00986552660.022
regulation of cell migrationGO:00303342190.022
protein secretionGO:00093061110.022
skeletal system morphogenesisGO:00487052030.022
organonitrogen compound biosynthetic processGO:19015661920.022
alcohol metabolic processGO:00060661160.022
purine nucleotide catabolic processGO:00061952110.021
regulation of epithelial cell proliferationGO:00506781410.021
negative regulation of cellular amino acid metabolic processGO:004576300.021
cellular ion homeostasisGO:00068731650.021
multi multicellular organism processGO:00447061090.021
negative regulation of molecular functionGO:00440922580.021
cytoplasmic transportGO:00164822340.021
positive regulation of kinase activityGO:00336741550.021
cellular response to lipopolysaccharideGO:0071222770.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.021
regulation of proteolysisGO:00301621640.021
nucleoside triphosphate catabolic processGO:00091432050.021
nucleotide catabolic processGO:00091662170.021
apoptotic signaling pathwayGO:00971903060.021
cellular response to lipidGO:00713961450.021
mapk cascadeGO:00001652810.020
regulation of mapk cascadeGO:00434082480.020
positive regulation of cell deathGO:00109422240.020
developmental maturationGO:00217001930.020
cellular homeostasisGO:00197252400.020
regulation of protein kinase activityGO:00458592320.020
cell type specific apoptotic processGO:00972852680.020
purine nucleoside catabolic processGO:00061522050.020
divalent metal ion transportGO:00708381720.020
cellular response to organic cyclic compoundGO:0071407870.020
regulation of reactive oxygen species metabolic processGO:2000377400.020
cellular response to molecule of bacterial originGO:0071219830.020
nucleotide metabolic processGO:00091173320.020
protein ubiquitinationGO:00165671710.020
purine ribonucleoside triphosphate catabolic processGO:00092071990.020
nucleoside triphosphate metabolic processGO:00091412300.020
positive regulation of protein phosphorylationGO:00019342420.020
male gamete generationGO:00482322850.020
regulation of anatomical structure sizeGO:00900661780.020
purine ribonucleoside catabolic processGO:00461302050.020
regulation of transferase activityGO:00513382630.019
inorganic ion transmembrane transportGO:00986602340.019
response to extracellular stimulusGO:00099911270.019
cell activation involved in immune responseGO:00022631260.019
organelle localizationGO:00516401790.019
protein modification by small protein conjugation or removalGO:00706472070.019
epithelial cell proliferationGO:00506731740.019
small gtpase mediated signal transductionGO:0007264970.019
regulation of hydrolase activityGO:00513362460.019
sequestering of metal ionGO:0051238190.019
ribonucleoside triphosphate metabolic processGO:00091992200.019
response to oxidative stressGO:00069791230.019
organophosphate catabolic processGO:00464342320.019
leukocyte chemotaxisGO:0030595690.018
negative regulation of protein maturationGO:1903318790.018
anatomical structure maturationGO:0071695490.018
lipid transportGO:0006869980.018
cell substrate adhesionGO:00315891300.018
renal system developmentGO:00720012250.018
organic acid biosynthetic processGO:0016053860.018
regulation of membrane potentialGO:00423911920.018
cellular response to growth factor stimulusGO:00713631970.018
response to radiationGO:00093141650.018
retrograde transport endosome to golgiGO:004214720.018
negative regulation of immune effector processGO:0002698550.018
cellular protein catabolic processGO:00442571550.018
regulation of purine nucleotide metabolic processGO:19005421690.018
protein modification by small protein conjugationGO:00324461870.018
exocytosisGO:00068871210.018
carbohydrate derivative biosynthetic processGO:19011371830.018
carboxylic acid biosynthetic processGO:0046394860.018
regulation of protein processingGO:0070613960.018
eosinophil migrationGO:007267730.018
regulation of monocyte chemotaxisGO:009002530.018
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.017
circulatory system processGO:00030131970.017
membrane fusionGO:0061025380.017
reactive oxygen species biosynthetic processGO:190340980.017
response to acid chemicalGO:00011011110.017
regulation of cellular response to stressGO:00801351590.017
regulation of cellular catabolic processGO:00313292420.017
regulation of apoptotic signaling pathwayGO:20012331970.017
peptidyl amino acid modificationGO:00181933360.017
skeletal muscle organ developmentGO:00605381630.017
regulation of innate immune responseGO:0045088910.017
regulation of eosinophil migrationGO:200041620.017
positive regulation of cell activationGO:00508671580.017
regulation of peptidase activityGO:0052547960.017
negative regulation of protein metabolic processGO:00512482820.017
divalent inorganic cation transportGO:00725111780.017
positive regulation of leukocyte mediated immunityGO:0002705700.017
developmental growth involved in morphogenesisGO:00605601380.017
positive regulation of protein transportGO:0051222930.016
negative regulation of phosphorus metabolic processGO:00105631840.016
cartilage developmentGO:00512161400.016
biomineral tissue developmentGO:0031214640.016
sensory organ morphogenesisGO:00905962420.016
anatomical structure homeostasisGO:00602491450.016
positive regulation of cytokine secretionGO:0050715410.016
response to growth factorGO:00708481980.016
production of molecular mediator of immune responseGO:00024401030.016
regulation of ras protein signal transductionGO:00465781140.016
negative regulation of hydrolase activityGO:0051346710.016
sensory perceptionGO:00076002450.016
positive regulation of immune effector processGO:00026991070.016
negative regulation of phosphorylationGO:00423261660.016
cell divisionGO:00513011200.016
urogenital system developmentGO:00016552610.016
regulation of t cell activationGO:00508631700.016
negative regulation of apoptotic signaling pathwayGO:20012341040.016
response to nutrient levelsGO:00316671090.016
regulation of homeostatic processGO:00328441820.015
peptide transportGO:00158331330.015
extracellular matrix organizationGO:00301981470.015
wound healingGO:00420601570.015
organic hydroxy compound transportGO:0015850930.015
neural precursor cell proliferationGO:00613511210.015
negative regulation of cellular component organizationGO:00511291940.015
skin developmentGO:00435882200.015
cellular chemical homeostasisGO:00550822150.015
positive regulation of secretionGO:00510471300.015
reactive nitrogen species metabolic processGO:200105700.015
stem cell proliferationGO:00720891170.015
regulation of nucleotide metabolic processGO:00061401690.015
negative regulation of phosphate metabolic processGO:00459361840.015
regulation of reactive oxygen species biosynthetic processGO:190342620.015
lymphocyte mediated immunityGO:00024491390.015
carboxylic acid transportGO:00469421000.015
tumor necrosis factor superfamily cytokine productionGO:0071706510.015
cellular calcium ion homeostasisGO:00068741190.015
cellular response to transforming growth factor beta stimulusGO:0071560880.015
actin cytoskeleton organizationGO:00300362200.015
organ growthGO:00352651170.015
steroid metabolic processGO:00082021190.015
organophosphate biosynthetic processGO:00904071220.015
myeloid leukocyte migrationGO:0097529570.015
development of primary female sexual characteristicsGO:0046545730.015
endomembrane system organizationGO:00102561470.015
intracellular protein transportGO:00068862040.015
negative regulation of protein modification processGO:00314001630.014
regulation of cell cycleGO:00517262810.014
second messenger mediated signalingGO:0019932730.014
regulation of endocytosisGO:0030100690.014
regulation of hormone levelsGO:00108172110.014
myeloid leukocyte activationGO:0002274830.014
negative regulation of macrophage chemotaxisGO:001076010.014
monocarboxylic acid biosynthetic processGO:0072330610.014
cellular response to amino acid stimulusGO:0071230290.014
camera type eye developmentGO:00430102660.014
locomotory behaviorGO:00076261950.014
negative regulation of t cell activationGO:0050868650.014
blood circulationGO:00080151950.014
cellular response to peptidoglycanGO:007122440.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
positive regulation of protein secretionGO:0050714520.014
compound eye developmentGO:004874910.014
maintenance of locationGO:0051235890.014
morphogenesis of a branching epitheliumGO:00611381930.014
cellular response to biotic stimulusGO:0071216920.014
bone developmentGO:00603481200.014
negative regulation of endopeptidase activityGO:0010951440.014
negative regulation of fat cell differentiationGO:0045599360.014
bone mineralizationGO:0030282540.014
antibacterial peptide biosynthetic processGO:000278020.014
cellular macromolecule catabolic processGO:00442652060.014
positive regulation of nucleotide metabolic processGO:00459811140.014
cellular response to acid chemicalGO:0071229680.014
cellular response to inorganic substanceGO:0071241370.014
mature dendritic cell differentiationGO:009702930.014
granulocyte migrationGO:0097530430.013
antimicrobial peptide biosynthetic processGO:000277720.013
leukocyte activation involved in immune responseGO:00023661260.013
regulation of lymphocyte proliferationGO:00506701170.013
lymphocyte proliferationGO:00466511640.013
regulation of myotube differentiationGO:0010830620.013
regulation of neuron deathGO:19012141340.013
gliogenesisGO:00420631410.013
posttranscriptional regulation of gene expressionGO:00106081550.013
response to transforming growth factor betaGO:0071559880.013
mitotic cell cycle processGO:19030471590.013
peptide metabolic processGO:0006518460.013
endocytosisGO:00068971680.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
adaptive immune responseGO:00022501550.013
angiogenesisGO:00015252010.013
kidney developmentGO:00018222130.013
cellular amide metabolic processGO:0043603580.013
axonogenesisGO:00074092740.013
regulation of protein serine threonine kinase activityGO:00719001570.013
negative regulation of lymphocyte activationGO:0051250910.013
cdc42 protein signal transductionGO:003248800.013
regulation of metal ion transportGO:00109591060.013
immune response regulating cell surface receptor signaling pathwayGO:0002768800.013
positive regulation of intracellular transportGO:0032388700.013
activation of immune responseGO:00022531380.013
regulation of multi organism processGO:00439001110.013
organelle fusionGO:0048284280.013
regulation of ossificationGO:00302781120.013
tumor necrosis factor productionGO:0032640500.013
regulation of adaptive immune responseGO:0002819900.012
positive regulation of cellular catabolic processGO:00313311480.012
extracellular structure organizationGO:00430621480.012
negative regulation of cell activationGO:00508661110.012
myeloid cell differentiationGO:00300992330.012
response to steroid hormoneGO:0048545560.012
development of primary sexual characteristicsGO:00451371430.012
protein localization to organelleGO:00333651850.012
negative regulation of macrophage apoptotic processGO:200011030.012
transmission of nerve impulseGO:0019226760.012
ear developmentGO:00435832000.012
neuronal action potentialGO:0019228540.012
cofactor metabolic processGO:0051186800.012
negative regulation of proteolysisGO:0045861740.012
positive regulation of mapk cascadeGO:00434101700.012
detection of fungusGO:001604620.012
tissue homeostasisGO:00018941150.012
regulation of stem cell proliferationGO:0072091780.012
regulation of purine nucleotide catabolic processGO:00331211220.012
regulation of cytoplasmic transportGO:19036491120.012
striated muscle cell developmentGO:00550021250.012
positive regulation of gtp catabolic processGO:0033126850.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
regulation of vasculature developmentGO:1901342880.012
female sex differentiationGO:0046660840.012
regulation of interleukin 8 productionGO:003267730.012
defense response to bacteriumGO:00427421190.012
positive regulation of nucleotide catabolic processGO:0030813880.012
regulation of cellular component biogenesisGO:00440871810.012
cellular response to oxidative stressGO:0034599760.012
regulation of fat cell differentiationGO:0045598810.012
negative regulation of protein phosphorylationGO:00019331260.012
positive regulation of eosinophil migrationGO:200041820.012
immune response activating signal transductionGO:00027571160.012
alpha beta t cell activationGO:0046631910.012
neuron apoptotic processGO:00514021420.012
morphogenesis of a branching structureGO:00017632030.012
alpha amino acid metabolic processGO:1901605590.012
regulation of t cell proliferationGO:0042129920.012
antimicrobial peptide productionGO:000277520.012
positive regulation of purine nucleotide catabolic processGO:0033123880.012
amino acid transmembrane transportGO:0003333370.012
peptide secretionGO:00027901140.012
action potentialGO:0001508780.011
synaptic transmissionGO:00072683290.011
regulation of tumor necrosis factor productionGO:0032680490.011
immune response regulating signaling pathwayGO:00027641250.011
cellular response to hormone stimulusGO:00328701500.011
leukocyte degranulationGO:0043299270.011
regulation of map kinase activityGO:00434051200.011
organic hydroxy compound biosynthetic processGO:1901617770.011
Mouse
gtp catabolic processGO:00061841430.011
plasma membrane organizationGO:0007009900.011
regulation of chemotaxisGO:0050920530.011
regulation of cell cycle processGO:00105641600.011
regulation of blood vessel sizeGO:0050880560.011
intestinal epithelial structure maintenanceGO:006072940.011
regulation of lipid biosynthetic processGO:0046890540.011
regulation of lymphocyte mediated immunityGO:0002706840.011
negative regulation of peptidase activityGO:0010466460.011
regulation of ion transmembrane transportGO:00347651190.011
thymocyte migrationGO:007267920.011
embryonic organ morphogenesisGO:00485622760.011
regulation of transmembrane transportGO:00347621280.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
protein targetingGO:00066051430.011
response to light stimulusGO:00094161350.011
vesicle fusionGO:0006906160.011
germ cell developmentGO:00072811850.011
interleukin 8 productionGO:003263740.011
female gonad developmentGO:0008585710.011
myoblast differentiationGO:0045445520.011
positive regulation of transferase activityGO:00513471670.011
calcium ion homeostasisGO:00550741270.011
chromatin organizationGO:00063252060.011
regulation of neuron differentiationGO:00456642810.011
regulation of protein maturationGO:1903317960.011
cell growthGO:00160491300.011
neutrophil chemotaxisGO:0030593360.011
inorganic anion transportGO:0015698430.011
organelle fissionGO:00482851700.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
regulation of blood pressureGO:0008217930.011
regulation of endopeptidase activityGO:0052548890.011
neuron deathGO:00709971540.011
lipid localizationGO:00108761260.011
b cell activationGO:00421131610.011
positive regulation of protein kinase activityGO:00458601440.011
positive regulation of epithelial cell proliferationGO:0050679680.010
syncytium formationGO:0006949430.010
nucleoside monophosphate metabolic processGO:0009123850.010
response to oxygen levelsGO:0070482620.010
glial cell differentiationGO:00100011310.010
positive regulation of nucleoside metabolic processGO:0045979910.010
guanosine containing compound metabolic processGO:19010681440.010
tube formationGO:00351481400.010
response to drugGO:0042493750.010
gonad developmentGO:00084061410.010
positive regulation of monocyte chemotaxisGO:009002620.010
regulation of tube sizeGO:0035150570.010
antibacterial peptide secretionGO:000277910.010
positive regulation of reactive oxygen species metabolic processGO:2000379110.010
organelle assemblyGO:00709251770.010
detection of external biotic stimulusGO:009858190.010
regulation of lipid metabolic processGO:00192161180.010
t cell mediated immunityGO:0002456500.010
response to reactive oxygen speciesGO:0000302560.010
positive regulation of innate immune responseGO:0045089800.010
positive regulation of ras gtpase activityGO:0032320650.010
t cell differentiationGO:00302171740.010
muscle system processGO:00030121410.010
limb morphogenesisGO:00351081490.010
regulation of exocytosisGO:0017157610.010
regulation of cell projection organizationGO:00313442060.010
body fluid secretionGO:0007589530.010
regulation of striated muscle cell differentiationGO:0051153810.010
leukocyte proliferationGO:00706611720.010
smooth muscle contractionGO:0006939440.010

Gpnmb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.024
nervous system diseaseDOID:86300.021
disease of anatomical entityDOID:700.021
musculoskeletal system diseaseDOID:1700.016
connective tissue diseaseDOID:6500.013
inherited metabolic disorderDOID:65500.011
eye and adnexa diseaseDOID:149200.010
eye diseaseDOID:561400.010
sensory system diseaseDOID:005015500.010