Mus musculus

0 known processes

Derl3

Der1-like domain family, member 3

(Aliases: derlin-3,IZP6,1810006I20Rik,MGC118672,1810063P04Rik,MGC144274,MGC144275)

Derl3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
inflammatory responseGO:00069542440.172
male gamete generationGO:00482322850.164
spermatogenesisGO:00072832840.159
pirna metabolic processGO:0034587120.124
germ cell developmentGO:00072811850.113
macromolecule catabolic processGO:00090572810.112
Human
dna metabolic processGO:00062593030.075
spermatid developmentGO:00072861080.074
positive regulation of programmed cell deathGO:00430682180.070
immune effector processGO:00022523210.060
regulation of membrane potentialGO:00423911920.059
methylationGO:00322591340.058
defense response to other organismGO:00985421970.056
regulation of defense responseGO:00313472330.052
positive regulation of cellular amine metabolic processGO:003324050.049
spermatid differentiationGO:00485151150.048
cellular macromolecule catabolic processGO:00442652060.048
Human
muscle tissue developmentGO:00605373080.047
fertilizationGO:00095661270.047
regulation of homeostatic processGO:00328441820.047
regulation of secretion by cellGO:19035302490.046
cytokine productionGO:00018163190.045
protein catabolic processGO:00301632210.045
Human
sequestering of calcium ionGO:0051208180.045
cellular ketone metabolic processGO:0042180840.044
negative regulation of cell activationGO:00508661110.043
regulation of innate immune responseGO:0045088910.038
striated muscle tissue developmentGO:00147062930.037
negative regulation of immune system processGO:00026832090.037
lipid biosynthetic processGO:00086101790.036
dna methylation involved in gamete generationGO:0043046150.036
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.036
regulation of transferase activityGO:00513382630.036
blood vessel morphogenesisGO:00485142850.036
regulation of hormone levelsGO:00108172110.035
axonogenesisGO:00074092740.035
positive regulation of cell motilityGO:20001471160.035
b cell activationGO:00421131610.034
multicellular organismal homeostasisGO:00488711640.034
sequestering of metal ionGO:0051238190.034
cellular lipid metabolic processGO:00442553230.034
action potentialGO:0001508780.033
maintenance of locationGO:0051235890.033
regulation of kinase activityGO:00435492490.033
intestinal epithelial structure maintenanceGO:006072940.033
macromolecule methylationGO:00434141200.032
positive regulation of cellular amino acid metabolic processGO:004576430.032
synaptic transmissionGO:00072683290.032
regulation of protein kinase activityGO:00458592320.031
cellular homeostasisGO:00197252400.031
positive regulation of protein modification processGO:00314012990.030
cellular protein catabolic processGO:00442571550.030
Human
oocyte axis specificationGO:000730920.029
positive regulation of cell deathGO:00109422240.029
endocytosisGO:00068971680.029
exocytosisGO:00068871210.029
regulation of cytokine productionGO:00018172660.028
organelle fissionGO:00482851700.028
organonitrogen compound biosynthetic processGO:19015661920.028
chromatin modificationGO:00165681870.028
regulation of cellular amino acid metabolic processGO:000652150.028
cellular amino acid metabolic processGO:00065201030.028
bone developmentGO:00603481200.027
male meiosisGO:0007140370.027
innate immune responseGO:00450871570.027
angiogenesisGO:00015252010.027
nuclear divisionGO:00002801580.027
meiotic cell cycleGO:00513211220.027
regulation of blood pressureGO:0008217930.026
chromatin organizationGO:00063252060.026
dna modificationGO:0006304500.026
protein maturationGO:00516041760.026
meiotic cell cycle processGO:1903046770.026
regulation of cellular ketone metabolic processGO:0010565660.026
glycerolipid metabolic processGO:00464861220.026
divalent inorganic cation transportGO:00725111780.026
positive regulation of cell activationGO:00508671580.026
myeloid cell differentiationGO:00300992330.025
meiosis iGO:0007127600.025
regulation of t cell activationGO:00508631700.025
positive regulation of cytokine productionGO:00018191740.025
organelle localizationGO:00516401790.025
regulation of inflammatory responseGO:00507271470.025
cellular chemical homeostasisGO:00550822150.025
positive regulation of apoptotic processGO:00430652170.024
cellular response to cytokine stimulusGO:00713451890.024
negative regulation of protein metabolic processGO:00512482820.024
defense response to bacteriumGO:00427421190.024
regulation of secretionGO:00510462740.024
cell type specific apoptotic processGO:00972852680.024
modification dependent macromolecule catabolic processGO:00436321330.024
Human
regulation of intracellular transportGO:00323861590.024
digestive system developmentGO:00551232000.024
glycoprotein metabolic processGO:00091001160.024
Human
cellular amine metabolic processGO:0044106440.023
heterocycle catabolic processGO:00467002800.023
meiotic nuclear divisionGO:00071261150.023
histone modificationGO:00165701590.023
regulation of cell motilityGO:20001452360.023
sperm motilityGO:0030317470.023
sulfur compound metabolic processGO:00067901000.023
positive regulation of transferase activityGO:00513471670.023
cation transportGO:00068123990.022
regulation of protein localizationGO:00328802310.022
protein processingGO:00164851630.022
regulation of lymphocyte activationGO:00512492400.022
extracellular matrix organizationGO:00301981470.022
ossificationGO:00015032160.022
carboxylic acid biosynthetic processGO:0046394860.022
transmembrane transportGO:00550854120.022
multicellular organismal signalingGO:0035637910.022
regulation of cell cycle processGO:00105641600.022
glucose homeostasisGO:00425931280.021
digestive tract developmentGO:00485651900.021
regulation of monocyte chemotaxisGO:009002530.021
negative regulation of cellular protein metabolic processGO:00322692470.021
humoral immune responseGO:0006959570.021
leukocyte migrationGO:00509001240.021
skeletal system developmentGO:00015013560.021
regulation of leukocyte differentiationGO:19021051590.021
calcium ion homeostasisGO:00550741270.021
regulation of synaptic growth at neuromuscular junctionGO:000858240.021
positive regulation of defense responseGO:00313491240.021
regulation of cell cycleGO:00517262810.020
response to lipopolysaccharideGO:00324961280.020
negative regulation of macrophage apoptotic processGO:200011030.020
metal ion homeostasisGO:00550651890.020
negative regulation of cell cycleGO:00457861230.020
neuronal action potentialGO:0019228540.020
heart morphogenesisGO:00030071780.020
homeostasis of number of cellsGO:00488722100.020
transmission of nerve impulseGO:0019226760.020
protein ubiquitinationGO:00165671710.020
organic cyclic compound catabolic processGO:19013612950.020
regulation of response to woundingGO:19030341890.020
lymphocyte mediated immunityGO:00024491390.019
posttranscriptional regulation of gene expressionGO:00106081550.019
leukocyte mediated immunityGO:00024431740.019
adaptive immune responseGO:00022501550.019
positive regulation of interferon alpha productionGO:003272740.019
rna interferenceGO:001624620.019
cytoplasmic transportGO:00164822340.019
negative regulation of homeostatic processGO:0032845710.019
epithelial cell proliferationGO:00506731740.019
g protein coupled receptor signaling pathwayGO:00071862430.018
multicellular organism growthGO:00352641610.018
tissue homeostasisGO:00018941150.018
nucleic acid phosphodiester bond hydrolysisGO:0090305490.018
circulatory system processGO:00030131970.018
organelle assemblyGO:00709251770.018
positive regulation of t cell activationGO:00508701010.018
respiratory system developmentGO:00605411900.018
myelinationGO:0042552740.018
small gtpase mediated signal transductionGO:0007264970.018
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.018
regulation of cell activationGO:00508652890.018
aromatic compound catabolic processGO:00194392860.018
epidermis developmentGO:00085441870.018
regulation of chromosome organizationGO:0033044830.018
wound healingGO:00420601570.018
ameboidal type cell migrationGO:00016671280.018
compound eye developmentGO:004874910.018
anatomical structure homeostasisGO:00602491450.017
cytokine biosynthetic processGO:0042089680.017
synapsisGO:0007129340.017
mapk cascadeGO:00001652810.017
positive regulation of kinase activityGO:00336741550.017
germ line stem cell divisionGO:004207820.017
regulation of alpha beta t cell activationGO:0046634530.017
regulation of adaptive immune responseGO:0002819900.017
protein modification by small protein conjugation or removalGO:00706472070.017
intracellular mrna localizationGO:000829840.017
vesicle localizationGO:0051648860.017
myeloid leukocyte migrationGO:0097529570.017
organic acid biosynthetic processGO:0016053860.017
negative regulation of intracellular signal transductionGO:19025321670.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
ion transmembrane transportGO:00342203610.016
membrane organizationGO:00610242450.016
negative regulation of molecular functionGO:00440922580.016
amine metabolic processGO:0009308450.016
positive regulation of protein kinase activityGO:00458601440.016
dna alkylationGO:0006305430.016
regulation of cellular amine metabolic processGO:0033238200.016
production of molecular mediator of immune responseGO:00024401030.016
positive regulation of lymphocyte differentiationGO:0045621610.016
inorganic cation transmembrane transportGO:00986622070.016
lymphocyte proliferationGO:00466511640.016
positive regulation of secretion by cellGO:19035321140.016
developmental maturationGO:00217001930.016
regionalizationGO:00030023370.016
connective tissue developmentGO:00614481790.016
cytokine metabolic processGO:0042107710.016
mature dendritic cell differentiationGO:009702930.015
immunoglobulin productionGO:0002377730.015
eosinophil migrationGO:007267730.015
positive regulation of cell migrationGO:00303351090.015
intracellular distribution of mitochondriaGO:004831210.015
proteolysis involved in cellular protein catabolic processGO:00516031470.015
Human
regulation of organelle organizationGO:00330432890.015
positive regulation of leukocyte differentiationGO:1902107860.015
regulation of interleukin 18 productionGO:003266130.015
monocarboxylic acid biosynthetic processGO:0072330610.015
regulation of antigen receptor mediated signaling pathwayGO:0050854290.015
immune response regulating signaling pathwayGO:00027641250.015
t cell activationGO:00421102890.015
reactive oxygen species metabolic processGO:0072593840.015
immune response activating signal transductionGO:00027571160.015
regulation of interleukin 8 productionGO:003267730.015
carbohydrate biosynthetic processGO:0016051740.015
covalent chromatin modificationGO:00165691630.015
digestive tract morphogenesisGO:00485461470.015
chromosome organization involved in meiosisGO:0070192390.015
cellular response to external stimulusGO:0071496880.015
regulation of cell migrationGO:00303342190.015
regulation of proteolysisGO:00301621640.015
protein secretionGO:00093061110.014
cardiac ventricle developmentGO:0003231830.014
interleukin 8 productionGO:003263740.014
leukocyte differentiationGO:00025213420.014
lateral inhibitionGO:004633110.014
hemostasisGO:0007599780.014
neuron apoptotic processGO:00514021420.014
tendon cell differentiationGO:003599040.014
regulation of ion transportGO:00432692150.014
endomembrane system organizationGO:00102561470.014
cellularizationGO:000734910.014
calcium mediated signalingGO:0019722460.014
positive regulation of immune effector processGO:00026991070.014
sensory organ morphogenesisGO:00905962420.014
blood circulationGO:00080151950.014
regulation of blood vessel sizeGO:0050880560.014
cation homeostasisGO:00550802120.014
positive regulation of protein phosphorylationGO:00019342420.014
positive regulation of proteolysisGO:0045862850.014
cation transmembrane transportGO:00986552660.014
mitochondrion distributionGO:004831140.014
embryonic appendage morphogenesisGO:00351131260.014
cell chemotaxisGO:0060326810.014
microtubule based processGO:00070172360.013
rhythmic processGO:00485111740.013
oocyte constructionGO:000730820.013
mesoderm formationGO:0001707620.013
stem cell differentiationGO:00488632680.013
tumor necrosis factor productionGO:0032640500.013
positive regulation of cell cycleGO:0045787920.013
regulation of striated muscle cell differentiationGO:0051153810.013
phospholipid metabolic processGO:0006644870.013
regulation of hydrolase activityGO:00513362460.013
production of molecular mediator involved in inflammatory responseGO:0002532210.013
hematopoietic progenitor cell differentiationGO:00022441430.013
oocyte maturationGO:0001556180.013
cellular response to biotic stimulusGO:0071216920.013
lipid localizationGO:00108761260.013
regulation of cellular catabolic processGO:00313292420.013
peptidyl amino acid modificationGO:00181933360.013
Human
membrane lipid biosynthetic processGO:0046467320.013
regulation of endocytosisGO:0030100690.013
cell fate commitmentGO:00451652100.013
dendrite developmentGO:00163581150.013
regulation of transpositionGO:001052820.013
regulation of embryonic developmentGO:0045995710.013
phagocytosisGO:0006909660.013
chemotaxisGO:00069352470.013
coagulationGO:0050817780.013
dna methylationGO:0006306430.013
granulocyte migrationGO:0097530430.013
cell cell recognitionGO:0009988440.013
negative regulation of cellular component organizationGO:00511291940.013
carbohydrate metabolic processGO:00059752300.013
Human
hexose transportGO:0008645560.013
positive regulation of innate immune responseGO:0045089800.013
positive regulation of secretionGO:00510471300.013
monocarboxylic acid metabolic processGO:00327871910.013
muscle tissue morphogenesisGO:0060415530.012
establishment of organelle localizationGO:00516561220.012
hormone secretionGO:00468791280.012
dna recombinationGO:0006310920.012
neuron deathGO:00709971540.012
cell divisionGO:00513011200.012
regulation of cell projection organizationGO:00313442060.012
divalent metal ion transportGO:00708381720.012
cellular modified amino acid metabolic processGO:0006575630.012
peptidyl lysine modificationGO:0018205770.012
regulation of apoptotic signaling pathwayGO:20012331970.012
cardiac muscle contractionGO:0060048320.012
myeloid leukocyte differentiationGO:00025731190.012
regulation of cytokine biosynthetic processGO:0042035590.012
response to radiationGO:00093141650.012
ribose phosphate metabolic processGO:00196932910.012
cardiac chamber morphogenesisGO:0003206930.012
positive regulation of neuron differentiationGO:00456661410.012
chromosome segregationGO:0007059480.012
regulation of lymphocyte proliferationGO:00506701170.012
positive regulation of t cell differentiationGO:0045582520.012
organophosphate biosynthetic processGO:00904071220.012
ensheathment of neuronsGO:0007272760.012
positive regulation of nervous system developmentGO:00519622210.012
nucleotide metabolic processGO:00091173320.012
response to molecule of bacterial originGO:00022371430.012
glial cell differentiationGO:00100011310.012
cell maturationGO:00484691270.012
purine containing compound metabolic processGO:00725213110.012
regulation of myeloid cell differentiationGO:0045637960.012
protein methylationGO:0006479810.012
negative regulation of multi organism processGO:0043901680.012
cellular ion homeostasisGO:00068731650.012
regulation of mitotic cell cycleGO:00073461260.012
ubiquitin dependent protein catabolic processGO:00065111290.012
Human
cardiac muscle tissue morphogenesisGO:0055008440.011
protein modification by small protein conjugationGO:00324461870.011
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.011
ovulation cycleGO:0042698590.011
regulation of neuron differentiationGO:00456642810.011
cytokine secretionGO:0050663720.011
positive regulation of hydrolase activityGO:00513451480.011
cellular response to abiotic stimulusGO:0071214560.011
regulation of lymphocyte differentiationGO:00456191070.011
negative regulation of cell proliferationGO:00082852960.011
mesoderm developmentGO:00074981000.011
neural tube developmentGO:00219151600.011
midgut developmentGO:000749440.011
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.011
regulation of vesicle mediated transportGO:00606271390.011
muscle cell differentiationGO:00426922610.011
neural precursor cell proliferationGO:00613511210.011
cartilage developmentGO:00512161400.011
wnt signaling pathwayGO:00160551880.011
regulation of transmembrane transportGO:00347621280.011
regulation of chromatin modificationGO:1903308570.011
fat cell differentiationGO:00454441600.011
eye photoreceptor cell differentiationGO:0001754410.011
second messenger mediated signalingGO:0019932730.011
regulation of interleukin 12 productionGO:0032655300.011
maternal determination of anterior posterior axis embryoGO:000835820.011
cellular response to molecule of bacterial originGO:0071219830.011
alpha beta t cell activationGO:0046631910.011
regulation of ossificationGO:00302781120.011
positive regulation of monocyte chemotaxisGO:009002620.011
regulation of protein catabolic processGO:00421761080.011
negative regulation of cytokine productionGO:0001818840.011
cardiac chamber developmentGO:00032051080.011
nucleobase containing small molecule metabolic processGO:00550863520.011
urogenital system developmentGO:00016552610.011
positive regulation of tumor necrosis factor productionGO:0032760300.011
fatty acid biosynthetic processGO:0006633410.011
nucleoside phosphate metabolic processGO:00067533380.011
gland developmentGO:00487323300.011
positive regulation of apoptotic signaling pathwayGO:2001235950.011
reactive oxygen species biosynthetic processGO:190340980.011
t cell proliferationGO:00420981200.011
leukocyte chemotaxisGO:0030595690.011
negative regulation of cholesterol transportGO:003237540.010
regulation of cellular response to stressGO:00801351590.010
pole plasm assemblyGO:000731520.010
skin developmentGO:00435882200.010
positive regulation of organelle organizationGO:00106381280.010
epithelial cell developmentGO:00020641590.010
positive regulation of response to woundingGO:1903036660.010
oocyte anterior posterior axis specificationGO:000731420.010
female gamete generationGO:0007292740.010
cellular calcium ion homeostasisGO:00068741190.010
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.010
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.010
dephosphorylationGO:00163111290.010
cellular metal ion homeostasisGO:00068751510.010
regulation of reactive oxygen species biosynthetic processGO:190342620.010
growth involved in symbiotic interactionGO:0044110230.010
cytokinetic processGO:003250620.010
regulation of eosinophil migrationGO:200041620.010
regulation of cellular component biogenesisGO:00440871810.010
cell killingGO:0001906670.010
modification dependent protein catabolic processGO:00199411330.010
Human
positive regulation of leukocyte mediated immunityGO:0002705700.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
glycosyl compound metabolic processGO:19016572460.010
response to organic cyclic compoundGO:00140701980.010
cellular response to dna damage stimulusGO:00069742070.010
bone mineralizationGO:0030282540.010
mitochondrion organizationGO:00070051340.010

Derl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.033
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.021
musculoskeletal system diseaseDOID:1700.019
connective tissue diseaseDOID:6500.018
disease of cellular proliferationDOID:1456600.016
organ system cancerDOID:005068600.012
cancerDOID:16200.012
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012
central nervous system diseaseDOID:33100.012
lupus erythematosusDOID:885700.011
hypersensitivity reaction diseaseDOID:006005600.011
hypersensitivity reaction type ii diseaseDOID:41700.011