IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Ddx39b

DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

(Aliases: 0610030D10Rik,MGC38799,AI428441,MGC19235,Bat1a,D17H6S81E,Bat1,D17H6S81E-1,D6S81Eh,Bat-1)

Entrez: 53817
Ensembl: ENSMUSG00000019432
UniProtKB: Q9Z1N5

Process Predictions
Disease Predictions

Ddx39b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
mrna splicing via spliceosome	GO:0000398	43	0.876	Human Yeast Fly
rna splicing via transesterification reactions	GO:0000375	43	0.765	Human Yeast Fly
mrna processing	GO:0006397	63	0.712	Human Yeast Fly
mrna metabolic process	GO:0016071	84	0.703	Human Yeast Fly
rna processing	GO:0006396	105	0.689	Human Yeast Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	43	0.595	Human Yeast Fly
regulation of rna splicing	GO:0043484	37	0.572	Fly
regulation of mrna metabolic process	GO:1903311	43	0.462	Fly
negative regulation of mrna processing	GO:0050686	12	0.421
rna splicing	GO:0008380	54	0.362	Human Yeast Fly
ribonucleoprotein complex subunit organization	GO:0071826	28	0.362	Human
alternative mrna splicing via spliceosome	GO:0000380	12	0.314	Fly
chromatin organization	GO:0006325	206	0.196	Fly
regulation of mrna processing	GO:0050684	41	0.188	Fly
regulation of mrna splicing via spliceosome	GO:0048024	32	0.186	Fly
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.150	Human
regulation of meiotic cell cycle	GO:0051445	34	0.137
dna dealkylation	GO:0035510	11	0.134
chromatin modification	GO:0016568	187	0.122	Fly
cellular response to dna damage stimulus	GO:0006974	207	0.102	Human Yeast
pole plasm assembly	GO:0007315	2	0.100
nucleoside metabolic process	GO:0009116	246	0.099	Human Yeast
negative regulation of rna splicing	GO:0033119	12	0.098
posttranscriptional regulation of gene expression	GO:0010608	155	0.096
negative regulation of cellular protein metabolic process	GO:0032269	247	0.094
posttranscriptional gene silencing	GO:0016441	10	0.083
positive regulation of nucleocytoplasmic transport	GO:0046824	30	0.081
negative regulation of mrna metabolic process	GO:1903312	13	0.080
stem cell development	GO:0048864	219	0.080
gene silencing by mirna	GO:0035195	10	0.076
rna catabolic process	GO:0006401	29	0.074
dna metabolic process	GO:0006259	303	0.072	Yeast
dna repair	GO:0006281	107	0.067	Yeast
organelle fission	GO:0048285	170	0.065
regulation of apoptotic signaling pathway	GO:2001233	197	0.064
primary mirna processing	GO:0031053	1	0.063
viral life cycle	GO:0019058	36	0.062	Human
positive regulation of intracellular transport	GO:0032388	70	0.061
glycosyl compound metabolic process	GO:1901657	246	0.059	Human Yeast
ribonucleoside metabolic process	GO:0009119	245	0.058	Human Yeast
heterocycle catabolic process	GO:0046700	280	0.055	Human Yeast
rna interference	GO:0016246	2	0.054
germ cell development	GO:0007281	185	0.053
gonad development	GO:0008406	141	0.053
regulation of cell cycle process	GO:0010564	160	0.053	Human
histone deubiquitination	GO:0016578	2	0.052
negative regulation of protein metabolic process	GO:0051248	282	0.051
development of primary sexual characteristics	GO:0045137	143	0.051
regulation of cell cycle	GO:0051726	281	0.049	Human
purine nucleoside catabolic process	GO:0006152	205	0.046	Human Yeast
positive regulation of rna splicing	GO:0033120	12	0.045
cellular ketone metabolic process	GO:0042180	84	0.044
multi multicellular organism process	GO:0044706	109	0.044
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	2	0.043
regulation of symbiosis encompassing mutualism through parasitism	GO:0043903	52	0.043
organic cyclic compound catabolic process	GO:1901361	295	0.042	Human Yeast
oocyte anterior posterior axis specification	GO:0007314	2	0.042
regulation of nuclear division	GO:0051783	56	0.042
cellular macromolecule catabolic process	GO:0044265	206	0.042
macromolecule catabolic process	GO:0009057	281	0.042
meiotic cell cycle	GO:0051321	122	0.041
negative regulation of molecular function	GO:0044092	258	0.041
intracellular protein transport	GO:0006886	204	0.040
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.040
organelle assembly	GO:0070925	177	0.040
regulation of organelle organization	GO:0033043	289	0.039
regulation of cellular catabolic process	GO:0031329	242	0.039
embryonic organ morphogenesis	GO:0048562	276	0.039
axonal fasciculation	GO:0007413	15	0.039
negative regulation of intracellular signal transduction	GO:1902532	167	0.038
nuclear division	GO:0000280	158	0.038
small gtpase mediated signal transduction	GO:0007264	97	0.036
cellular amino acid metabolic process	GO:0006520	103	0.036
negative regulation of cell proliferation	GO:0008285	296	0.036
aromatic compound catabolic process	GO:0019439	286	0.036	Human Yeast
nuclear transcribed mrna catabolic process nonsense mediated decay	GO:0000184	1	0.035
nucleocytoplasmic transport	GO:0006913	139	0.035	Human Yeast Fly
neuron projection guidance	GO:0097485	141	0.035
oxidation reduction process	GO:0055114	342	0.034
regulation of nucleocytoplasmic transport	GO:0046822	73	0.034
regulation of mrna stability	GO:0043488	23	0.034
positive regulation of mrna metabolic process	GO:1903313	17	0.034
covalent chromatin modification	GO:0016569	163	0.033
regulation of intracellular transport	GO:0032386	159	0.033
regulation of protein transport	GO:0051223	163	0.032
positive regulation of cell death	GO:0010942	224	0.032
negative regulation of mrna splicing via spliceosome	GO:0048025	12	0.032
positive regulation of apoptotic process	GO:0043065	217	0.031
intracellular receptor signaling pathway	GO:0030522	74	0.031
mitotic cell cycle process	GO:1903047	159	0.030	Fly
regulation of alternative mrna splicing via spliceosome	GO:0000381	8	0.030	Fly
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.030
interspecies interaction between organisms	GO:0044419	83	0.030	Human
negative regulation of protein serine threonine kinase activity	GO:0071901	49	0.029
leukocyte differentiation	GO:0002521	342	0.028
meiotic nuclear division	GO:0007126	115	0.028
regulation of cytoplasmic transport	GO:1903649	112	0.028
amine metabolic process	GO:0009308	45	0.027
segmentation	GO:0035282	93	0.027
regulation of protein localization	GO:0032880	231	0.026
carbohydrate derivative catabolic process	GO:1901136	231	0.026	Human Yeast
positive regulation of programmed cell death	GO:0043068	218	0.026
stem cell differentiation	GO:0048863	268	0.026
negative regulation of mitotic cell cycle	GO:0045930	58	0.025
purine nucleotide metabolic process	GO:0006163	302	0.025	Human Yeast
vitamin d receptor signaling pathway	GO:0070561	2	0.025
apoptotic signaling pathway	GO:0097190	306	0.025
blood circulation	GO:0008015	195	0.025
mitotic cell cycle	GO:0000278	195	0.025	Fly
regulation of protein kinase activity	GO:0045859	232	0.024
purine containing compound metabolic process	GO:0072521	311	0.024	Human Yeast
cellular amine metabolic process	GO:0044106	44	0.024
receptor mediated endocytosis	GO:0006898	51	0.024
antimicrobial peptide production	GO:0002775	2	0.024
defense response to bacterium	GO:0042742	119	0.024
trna wobble uridine modification	GO:0002098	2	0.024
chemotaxis	GO:0006935	247	0.023
peptidyl amino acid modification	GO:0018193	336	0.023
spermatogenesis	GO:0007283	284	0.023
response to organic cyclic compound	GO:0014070	198	0.023
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045899	2	0.023
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	3	0.022
regulation of establishment of protein localization	GO:0070201	181	0.022
cellular nitrogen compound catabolic process	GO:0044270	280	0.022	Human Yeast
nucleotide catabolic process	GO:0009166	217	0.022	Human Yeast
molting cycle	GO:0042303	90	0.021
regulation of response to dna damage stimulus	GO:2001020	34	0.021	Human
changes to dna methylation involved in embryo development	GO:1901538	6	0.021
positive regulation of mrna processing	GO:0050685	16	0.021
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.021
cytoplasmic transport	GO:0016482	234	0.021	Human Yeast Fly
purine containing compound catabolic process	GO:0072523	213	0.021	Human Yeast
rna localization	GO:0006403	23	0.021	Human Yeast Fly
metal ion homeostasis	GO:0055065	189	0.021
oogenesis	GO:0048477	56	0.021
mitotic cell cycle checkpoint	GO:0007093	31	0.020
cellular response to cytokine stimulus	GO:0071345	189	0.020
regulation of cell division	GO:0051302	76	0.020
negative regulation of phagocytosis	GO:0050765	4	0.020
regulation of generation of precursor metabolites and energy	GO:0043467	38	0.020
negative regulation of phosphorylation	GO:0042326	166	0.020
nitrogen compound transport	GO:0071705	271	0.020	Human Yeast Fly
posttranscriptional gene silencing by rna	GO:0035194	10	0.020
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	1	0.019
oocyte construction	GO:0007308	2	0.019
protein targeting	GO:0006605	143	0.019
cation homeostasis	GO:0055080	212	0.019
cellular protein complex assembly	GO:0043623	116	0.019
regulation of multi organism process	GO:0043900	111	0.019
organonitrogen compound biosynthetic process	GO:1901566	192	0.018
transmembrane transport	GO:0055085	412	0.018
cell division	GO:0051301	120	0.018
hematopoietic progenitor cell differentiation	GO:0002244	143	0.018
regulation of cell cycle phase transition	GO:1901987	77	0.018
viral process	GO:0016032	41	0.018	Human
negative regulation of phosphorus metabolic process	GO:0010563	184	0.018
cellular protein complex disassembly	GO:0043624	36	0.018
regulation of neuron differentiation	GO:0045664	281	0.018
positive regulation of dna repair	GO:0045739	3	0.018
dna methylation involved in embryo development	GO:0043045	6	0.018
circadian rhythm	GO:0007623	114	0.018
regulation of chromatin modification	GO:1903308	57	0.017
nucleobase containing small molecule metabolic process	GO:0055086	352	0.017	Human Yeast
regulation of protein targeting	GO:1903533	61	0.017
positive regulation of protein modification process	GO:0031401	299	0.017
production of small rna involved in gene silencing by rna	GO:0070918	6	0.017
intracellular mrna localization	GO:0008298	4	0.017
cation transport	GO:0006812	399	0.017
protein complex disassembly	GO:0043241	40	0.017
purine ribonucleoside metabolic process	GO:0046128	241	0.016	Human Yeast
regulation of rna export from nucleus	GO:0046831	4	0.016
dendrite development	GO:0016358	115	0.016
ras protein signal transduction	GO:0007265	77	0.016
regulation of intracellular protein transport	GO:0033157	82	0.016
regulation of membrane potential	GO:0042391	192	0.016
mitochondrion organization	GO:0007005	134	0.016
negative regulation of kinase activity	GO:0033673	81	0.016
stem cell maintenance	GO:0019827	130	0.016
regulation of intrinsic apoptotic signaling pathway	GO:2001242	61	0.016
regulation of hormone levels	GO:0010817	211	0.016
locomotory behavior	GO:0007626	195	0.016
cognition	GO:0050890	149	0.015
nuclear transcribed mrna catabolic process	GO:0000956	16	0.015
extrinsic apoptotic signaling pathway	GO:0097191	126	0.015
generation of precursor metabolites and energy	GO:0006091	103	0.015
apoptotic nuclear changes	GO:0030262	9	0.015
regulation of nucleotide metabolic process	GO:0006140	169	0.015
regulation of cellular amino acid metabolic process	GO:0006521	5	0.015
methylation	GO:0032259	134	0.015
atp metabolic process	GO:0046034	75	0.015	Human Yeast
developmental growth involved in morphogenesis	GO:0060560	138	0.015
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.015	Human Yeast
adult behavior	GO:0030534	135	0.015
negative regulation of viral process	GO:0048525	23	0.015
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.015
regulation of cellular ketone metabolic process	GO:0010565	66	0.015
innate immune response	GO:0045087	157	0.015
protein import into nucleus	GO:0006606	95	0.015
maintenance of location	GO:0051235	89	0.015
divalent inorganic cation homeostasis	GO:0072507	138	0.015
peptidyl lysine modification	GO:0018205	77	0.015
angiogenesis	GO:0001525	201	0.014
epithelial tube morphogenesis	GO:0060562	303	0.014
regulation of kinase activity	GO:0043549	249	0.014
regulation of viral release from host cell	GO:1902186	6	0.014
cellular response to lipid	GO:0071396	145	0.014
ion transmembrane transport	GO:0034220	361	0.014
positive regulation of growth	GO:0045927	104	0.014
purine ribonucleoside catabolic process	GO:0046130	205	0.014	Human Yeast
histone h4 acetylation	GO:0043967	10	0.014
nucleoside phosphate metabolic process	GO:0006753	338	0.014	Human Yeast
regulation of histone modification	GO:0031056	56	0.014
axon guidance	GO:0007411	141	0.014
gland development	GO:0048732	330	0.014
blastoderm segmentation	GO:0007350	13	0.014
calcium ion homeostasis	GO:0055074	127	0.014
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.014
base excision repair	GO:0006284	9	0.014
regulation of protein import into nucleus	GO:0042306	52	0.014
regulation of neuron death	GO:1901214	134	0.014
axonogenesis	GO:0007409	274	0.014
positive regulation of mrna splicing via spliceosome	GO:0048026	11	0.014
protein ubiquitination	GO:0016567	171	0.014
negative regulation of phosphate metabolic process	GO:0045936	184	0.013
regulation of lymphocyte activation	GO:0051249	240	0.013
response to lipopolysaccharide	GO:0032496	128	0.013
positive regulation of cellular amine metabolic process	GO:0033240	5	0.013
connective tissue development	GO:0061448	179	0.013
demethylation	GO:0070988	23	0.013
negative regulation of cellular amine metabolic process	GO:0033239	1	0.013
regulation of ras protein signal transduction	GO:0046578	114	0.013
protein processing	GO:0016485	163	0.013
positive regulation of protein transport	GO:0051222	93	0.013
regulation of transferase activity	GO:0051338	263	0.013
3 utr mediated mrna stabilization	GO:0070935	2	0.013
regulation of cellular component biogenesis	GO:0044087	181	0.013
rhythmic process	GO:0048511	174	0.013
protein modification by small protein conjugation or removal	GO:0070647	207	0.013
nuclear transport	GO:0051169	139	0.013	Human Yeast Fly
mrna transport	GO:0051028	13	0.013	Human Yeast Fly
regulation of response to alcohol	GO:1901419	2	0.012
regulation of protein serine threonine kinase activity	GO:0071900	157	0.012
embryonic axis specification	GO:0000578	30	0.012
nucleotide metabolic process	GO:0009117	332	0.012	Human Yeast
ribonucleotide metabolic process	GO:0009259	291	0.012	Human Yeast
neuroblast differentiation	GO:0014016	2	0.012
regulation of cell projection organization	GO:0031344	206	0.012
regulation of protein complex assembly	GO:0043254	83	0.012
adult locomotory behavior	GO:0008344	91	0.012
dna templated transcription initiation	GO:0006352	13	0.012
positive regulation of organelle organization	GO:0010638	128	0.012
negative regulation of cell cycle phase transition	GO:1901988	48	0.012
positive regulation of myeloid cell differentiation	GO:0045639	43	0.012
ribose phosphate metabolic process	GO:0019693	291	0.012	Human Yeast
endocytosis	GO:0006897	168	0.012
histone modification	GO:0016570	159	0.012
nuclear export	GO:0051168	34	0.012	Human Yeast Fly
regulation of protein complex disassembly	GO:0043244	28	0.012
positive regulation of hydrolase activity	GO:0051345	148	0.012
wnt signaling pathway	GO:0016055	188	0.012
ncrna processing	GO:0034470	26	0.012
positive regulation of nucleotide metabolic process	GO:0045981	114	0.012
lymphocyte proliferation	GO:0046651	164	0.012
embryonic skeletal system morphogenesis	GO:0048704	91	0.012
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.012	Human Yeast
defense response to other organism	GO:0098542	197	0.012
stem cell fate specification	GO:0048866	3	0.012
mrna catabolic process	GO:0006402	22	0.011
positive regulation of intracellular protein transport	GO:0090316	42	0.011
regulation of wnt signaling pathway	GO:0030111	123	0.011
carboxylic acid biosynthetic process	GO:0046394	86	0.011
ribonucleotide catabolic process	GO:0009261	208	0.011	Human Yeast
nucleobase containing compound transport	GO:0015931	27	0.011	Human Yeast Fly
viral gene expression	GO:0019080	3	0.011
nucleoside phosphate catabolic process	GO:1901292	222	0.011	Human Yeast
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.011	Human Yeast
trna wobble base modification	GO:0002097	2	0.011
regulation of mitochondrion organization	GO:0010821	27	0.011
regulation of nucleotide catabolic process	GO:0030811	122	0.011
purine ribonucleotide metabolic process	GO:0009150	290	0.011	Human Yeast
protein acylation	GO:0043543	64	0.011
response to oxidative stress	GO:0006979	123	0.011
regulation of rna stability	GO:0043487	26	0.011
purine nucleotide catabolic process	GO:0006195	211	0.011	Human Yeast
blastocyst hatching	GO:0001835	4	0.011
cellular homeostasis	GO:0019725	240	0.011
mesenchymal cell development	GO:0014031	93	0.010
dna demethylation	GO:0080111	10	0.010
macromolecular complex disassembly	GO:0032984	43	0.010
gene silencing by rna	GO:0031047	19	0.010
response to acid chemical	GO:0001101	111	0.010
pharynx development	GO:0060465	1	0.010
cell recognition	GO:0008037	83	0.010
negative regulation of protein modification process	GO:0031400	163	0.010
negative regulation of transferase activity	GO:0051348	85	0.010

Ddx39b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.040
nervous system disease	DOID:863	0.040
central nervous system disease	DOID:331	0.018
neurodegenerative disease	DOID:1289	0.018
eye disease	DOID:5614	0.015
retinal disease	DOID:5679	0.015
sensory system disease	DOID:0050155	0.015
eye and adnexa disease	DOID:1492	0.015
disease of mental health	DOID:150	0.012
retinal degeneration	DOID:8466	0.011

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