Mus musculus

32 known processes

Tpx2

TPX2, microtubule-associated protein homolog (Xenopus laevis)

(Aliases: 2610005B21Rik,REPP86,p100,DIL2)

Tpx2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitotic cell cycleGO:00002781950.396
mitotic cell cycle processGO:19030471590.276
organelle fissionGO:00482851700.244
mitotic sister chromatid cohesionGO:000706410.237
nuclear divisionGO:00002801580.147
microtubule based processGO:00070172360.144
microtubule polymerization or depolymerizationGO:0031109260.121
regulation of cell cycleGO:00517262810.116
meiotic cell cycleGO:00513211220.098
metaphase plate congressionGO:005131020.090
maintenance of locationGO:0051235890.088
regulation of microtubule based processGO:0032886520.084
meiotic cell cycle processGO:1903046770.082
regulation of cohesin localization to chromatinGO:007192210.081
male gamete generationGO:00482322850.079
germ cell developmentGO:00072811850.079
organic cyclic compound catabolic processGO:19013612950.079
cellular amine metabolic processGO:0044106440.079
regulation of microtubule polymerization or depolymerizationGO:0031110200.077
microtubule cytoskeleton organizationGO:00002261570.074
negative regulation of protein metabolic processGO:00512482820.070
dna metabolic processGO:00062593030.069
ubiquitin dependent protein catabolic processGO:00065111290.068
negative regulation of phosphorus metabolic processGO:00105631840.068
cellular amino acid metabolic processGO:00065201030.067
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.066
t cell activationGO:00421102890.065
male meiosisGO:0007140370.064
microtubule cytoskeleton organization involved in mitosisGO:190285040.062
negative regulation of molecular functionGO:00440922580.062
attachment of spindle microtubules to kinetochoreGO:000860840.061
regulation of mitotic cell cycleGO:00073461260.057
posttranscriptional regulation of gene expressionGO:00106081550.056
regulation of microtubule cytoskeleton organizationGO:0070507370.056
macromolecule catabolic processGO:00090572810.054
apoptotic signaling pathwayGO:00971903060.054
nucleobase containing small molecule metabolic processGO:00550863520.052
regulation of cell cycle processGO:00105641600.052
nucleoside phosphate metabolic processGO:00067533380.051
negative regulation of cell activationGO:00508661110.051
cellular response to dna damage stimulusGO:00069742070.050
oxidation reduction processGO:00551143420.049
cellular ketone metabolic processGO:0042180840.049
organelle assemblyGO:00709251770.049
protein catabolic processGO:00301632210.047
regulation of cell activationGO:00508652890.047
cellular macromolecule catabolic processGO:00442652060.045
regulation of kinase activityGO:00435492490.045
negative regulation of phosphate metabolic processGO:00459361840.045
regulation of lymphocyte activationGO:00512492400.044
microtubule polymerizationGO:0046785120.044
regulation of endopeptidase activityGO:0052548890.043
cytoplasmic transportGO:00164822340.043
negative regulation of cellular protein metabolic processGO:00322692470.042
protein maturationGO:00516041760.042
regulation of organelle organizationGO:00330432890.041
regulation of t cell activationGO:00508631700.040
negative regulation of cell cycle phase transitionGO:1901988480.040
smoothened signaling pathwayGO:00072241050.039
regulation of protein serine threonine kinase activityGO:00719001570.038
positive regulation of kinase activityGO:00336741550.038
negative regulation of cell cycleGO:00457861230.037
sensory perceptionGO:00076002450.037
cation transportGO:00068123990.037
blood vessel morphogenesisGO:00485142850.037
regulation of intracellular transportGO:00323861590.036
adaptive immune responseGO:00022501550.036
spermatogenesisGO:00072832840.036
regulation of cellular amino acid metabolic processGO:000652150.035
somite developmentGO:0061053810.035
lymphocyte differentiationGO:00300982420.035
ribonucleoside metabolic processGO:00091192450.035
negative regulation of phosphorylationGO:00423261660.035
cellular homeostasisGO:00197252400.035
positive regulation of apoptotic processGO:00430652170.034
regulation of cellular catabolic processGO:00313292420.034
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.033
response to nutrient levelsGO:00316671090.033
cellular protein complex assemblyGO:00436231160.033
positive regulation of organelle organizationGO:00106381280.033
spindle assembly involved in mitosisGO:009030740.033
heterocycle catabolic processGO:00467002800.033
aromatic compound catabolic processGO:00194392860.033
regulation of protein kinase activityGO:00458592320.033
regulation of transferase activityGO:00513382630.033
response to organic cyclic compoundGO:00140701980.032
lymphocyte mediated immunityGO:00024491390.032
sensory perception of soundGO:0007605970.032
angiogenesisGO:00015252010.031
purine nucleotide metabolic processGO:00061633020.031
notch signaling pathwayGO:0007219710.030
regulation of chromatin silencingGO:003193520.030
regulation of protein localizationGO:00328802310.030
cellular nitrogen compound catabolic processGO:00442702800.030
negative regulation of t cell activationGO:0050868650.029
regulation of microtubule polymerizationGO:003111370.028
regulation of cellular amine metabolic processGO:0033238200.028
cytokinetic processGO:003250620.028
cell adhesionGO:00071553290.028
nucleoside monophosphate metabolic processGO:0009123850.027
regulation of protein catabolic processGO:00421761080.027
negative regulation of cell proliferationGO:00082852960.027
glycosyl compound catabolic processGO:19016582060.027
sensory perception of mechanical stimulusGO:00509541070.027
leukocyte differentiationGO:00025213420.027
positive regulation of cellular amino acid metabolic processGO:004576430.027
regulation of protein processingGO:0070613960.027
blastocyst developmentGO:0001824800.027
purine nucleotide catabolic processGO:00061952110.027
positive regulation of protein modification processGO:00314012990.026
mitotic cytokinesisGO:000028140.026
regionalizationGO:00030023370.026
regulation of hydrolase activityGO:00513362460.026
protein localization to organelleGO:00333651850.026
positive regulation of chromosome segregationGO:005198440.025
regulation of cellular ketone metabolic processGO:0010565660.025
sprouting angiogenesisGO:0002040260.024
negative regulation of microtubule polymerization or depolymerizationGO:0031111150.024
carbohydrate derivative biosynthetic processGO:19011371830.024
response to extracellular stimulusGO:00099911270.024
positive regulation of cell cycleGO:0045787920.024
lateral inhibitionGO:004633110.024
nucleocytoplasmic transportGO:00069131390.023
cellular chemical homeostasisGO:00550822150.023
purine containing compound metabolic processGO:00725213110.023
ribose phosphate metabolic processGO:00196932910.023
purine nucleoside metabolic processGO:00422782410.022
negative regulation of protein processingGO:0010955790.022
branching morphogenesis of an epithelial tubeGO:00487541590.022
regulation of cellular component biogenesisGO:00440871810.022
single organismal cell cell adhesionGO:00163371310.022
negative regulation of lymphocyte differentiationGO:0045620320.022
ribonucleotide metabolic processGO:00092592910.022
response to peptideGO:19016521360.022
positive regulation of protein kinase activityGO:00458601440.021
centrosome separationGO:005129940.021
positive regulation of cellular catabolic processGO:00313311480.021
negative regulation of protein phosphorylationGO:00019331260.021
response to organonitrogen compoundGO:00102432460.021
regulation of epithelial cell proliferationGO:00506781410.021
negative regulation of lymphocyte activationGO:0051250910.021
positive regulation of protein catabolic processGO:0045732600.021
positive regulation of epithelial cell proliferationGO:0050679680.021
purine nucleoside catabolic processGO:00061522050.021
regulation of phosphoprotein phosphatase activityGO:004366630.021
nucleotide metabolic processGO:00091173320.020
intrinsic apoptotic signaling pathwayGO:00971931320.020
cellular response to cytokine stimulusGO:00713451890.020
regulation of secretionGO:00510462740.020
macromolecule methylationGO:00434141200.020
microtubule based movementGO:0007018840.020
negative regulation of leukocyte differentiationGO:1902106510.020
negative regulation of transferase activityGO:0051348850.020
somitogenesisGO:0001756690.020
cleavage furrow formationGO:003608920.020
negative regulation of cellular component organizationGO:00511291940.020
regulation of protein stabilityGO:0031647520.019
female meiosis chromosome segregationGO:001632110.019
negative regulation of cell developmentGO:00107211690.019
negative regulation of kinase activityGO:0033673810.019
ribonucleotide catabolic processGO:00092612080.019
ribonucleoside catabolic processGO:00424542060.019
regulation of chromosome organizationGO:0033044830.019
regulation of cell adhesionGO:00301551540.019
nucleoside phosphate catabolic processGO:19012922220.019
g1 s transition of mitotic cell cycleGO:0000082570.019
small gtpase mediated signal transductionGO:0007264970.019
regulation of somitogenesisGO:001480760.019
protein modification by small protein conjugation or removalGO:00706472070.019
dephosphorylationGO:00163111290.019
organelle localizationGO:00516401790.019
glycosyl compound metabolic processGO:19016572460.018
synapsisGO:0007129340.018
protein importGO:00170381010.018
cellular response to lipidGO:00713961450.018
regulation of establishment of protein localizationGO:00702011810.018
negative regulation of protein modification processGO:00314001630.018
covalent chromatin modificationGO:00165691630.018
cilium assemblyGO:0042384810.018
double strand break repairGO:0006302480.018
positive regulation of cellular amine metabolic processGO:003324050.018
epithelial cell proliferationGO:00506731740.018
organonitrogen compound catabolic processGO:19015652640.018
regulation of protein maturationGO:1903317960.018
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.018
cellular carbohydrate metabolic processGO:00442621190.018
regulation of cell divisionGO:0051302760.018
t cell differentiationGO:00302171740.018
stem cell differentiationGO:00488632680.018
positive regulation of chromosome organizationGO:2001252330.018
amine metabolic processGO:0009308450.018
regulation of spindle organizationGO:009022420.017
morphogenesis of a branching structureGO:00017632030.017
regulation of embryonic developmentGO:0045995710.017
chromosome segregationGO:0007059480.017
meiotic nuclear divisionGO:00071261150.017
leukocyte mediated immunityGO:00024431740.017
regulation of cysteine type endopeptidase activityGO:2000116650.017
regulation of leukocyte differentiationGO:19021051590.017
regulation of protein transportGO:00512231630.017
microtubule nucleationGO:000702020.017
development of primary sexual characteristicsGO:00451371430.017
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.017
establishment of spindle localizationGO:0051293190.017
rhythmic processGO:00485111740.017
intracellular protein transportGO:00068862040.017
cohesin localization to chromatinGO:007192110.017
regulation of cytoplasmic transportGO:19036491120.016
protein localization to chromatinGO:007116830.016
protein polymerizationGO:0051258570.016
proteolysis involved in cellular protein catabolic processGO:00516031470.016
regulation of bindingGO:00510981110.016
dna damage response signal transduction resulting in transcriptionGO:004277220.016
mapk cascadeGO:00001652810.016
nucleoside triphosphate metabolic processGO:00091412300.016
mitotic nuclear divisionGO:0007067480.016
positive regulation of protein phosphorylationGO:00019342420.016
digestive system developmentGO:00551232000.016
regulation of response to woundingGO:19030341890.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
regulation of t cell differentiationGO:0045580830.015
positive regulation of endothelial cell proliferationGO:0001938170.015
proteasomal protein catabolic processGO:0010498980.015
regulation of secretion by cellGO:19035302490.015
response to radiationGO:00093141650.015
cellular response to external stimulusGO:0071496880.015
purine nucleoside triphosphate metabolic processGO:00091442260.015
negative regulation of mitotic cell cycleGO:0045930580.015
regulation of neural precursor cell proliferationGO:2000177700.015
myeloid cell differentiationGO:00300992330.015
purine ribonucleoside metabolic processGO:00461282410.015
protein modification by small protein conjugationGO:00324461870.015
cell type specific apoptotic processGO:00972852680.015
epithelial tube morphogenesisGO:00605623030.015
ossificationGO:00015032160.015
muscle cell differentiationGO:00426922610.015
nuclear importGO:0051170950.015
modification dependent protein catabolic processGO:00199411330.015
lymphocyte proliferationGO:00466511640.015
organophosphate catabolic processGO:00464342320.015
response to acid chemicalGO:00011011110.014
generation of precursor metabolites and energyGO:00060911030.014
blastocyst growthGO:0001832230.014
positive regulation of mitotic metaphase anaphase transitionGO:004584220.014
regulation of lymphocyte proliferationGO:00506701170.014
purine ribonucleoside catabolic processGO:00461302050.014
wnt signaling pathwayGO:00160551880.014
stem cell maintenanceGO:00198271300.014
cellular response to hormone stimulusGO:00328701500.014
regulation of adaptive immune responseGO:0002819900.014
cellular response to peptide hormone stimulusGO:0071375920.014
establishment or maintenance of cell polarityGO:0007163860.014
leukocyte proliferationGO:00706611720.014
t cell proliferationGO:00420981200.014
forebrain developmentGO:00309003020.014
regulation of cytoskeleton organizationGO:00514931220.014
regulation of nucleocytoplasmic transportGO:0046822730.014
chromatin modificationGO:00165681870.014
peptide transportGO:00158331330.014
ribonucleoside triphosphate metabolic processGO:00091992200.014
positive regulation of cell developmentGO:00107202370.014
striated muscle tissue developmentGO:00147062930.013
dna biosynthetic processGO:0071897220.013
cilium morphogenesisGO:00602711020.013
circadian regulation of gene expressionGO:0032922480.013
cell maturationGO:00484691270.013
divalent metal ion transportGO:00708381720.013
innate immune responseGO:00450871570.013
positive regulation of metaphase anaphase transition of cell cycleGO:190210120.013
spindle localizationGO:0051653220.013
muscle tissue developmentGO:00605373080.013
negative regulation of apoptotic signaling pathwayGO:20012341040.013
energy derivation by oxidation of organic compoundsGO:0015980770.013
sequestering of calcium ionGO:0051208180.013
activation of adenylate cyclase activityGO:000719040.013
cell activation involved in immune responseGO:00022631260.013
cell divisionGO:00513011200.013
homeostasis of number of cellsGO:00488722100.013
cytoskeleton dependent intracellular transportGO:0030705500.013
dna recombinationGO:0006310920.013
multi multicellular organism processGO:00447061090.013
establishment of organelle localizationGO:00516561220.013
purine ribonucleotide catabolic processGO:00091542080.013
microtubule based transportGO:0010970500.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
locomotory behaviorGO:00076261950.012
regulation of proteolysisGO:00301621640.012
regulation of mitotic cell cycle phase transitionGO:1901990730.012
cytokinesisGO:0000910170.012
negative regulation of growthGO:0045926990.012
embryonic epithelial tube formationGO:00018381300.012
negative regulation of endopeptidase activityGO:0010951440.012
regulation of auditory receptor cell differentiationGO:004560740.012
production of molecular mediator of immune responseGO:00024401030.012
regulation of lymphocyte differentiationGO:00456191070.012
morphogenesis of a branching epitheliumGO:00611381930.012
endomembrane system organizationGO:00102561470.012
nucleoside triphosphate catabolic processGO:00091432050.012
skeletal muscle organ developmentGO:00605381630.012
carbohydrate derivative catabolic processGO:19011362310.012
purine ribonucleotide metabolic processGO:00091502900.012
response to insulinGO:00328681000.012
small molecule biosynthetic processGO:00442831320.012
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.012
membrane organizationGO:00610242450.012
regulation of cellular component sizeGO:00325351210.012
nucleotide catabolic processGO:00091662170.012
negative regulation of cation channel activityGO:200125810.012
negative regulation of protein maturationGO:1903318790.012
mitotic spindle organizationGO:0007052100.012
nucleic acid phosphodiester bond hydrolysisGO:0090305490.012
cellular response to extracellular stimulusGO:0031668810.012
immune effector processGO:00022523210.012
regulation of cellular protein catabolic processGO:1903362610.012
positive regulation of histone methylationGO:0031062160.011
protein autophosphorylationGO:0046777610.011
positive regulation of transferase activityGO:00513471670.011
cytokine productionGO:00018163190.011
regulation of notch signaling pathwayGO:0008593350.011
establishment of protein localization to organelleGO:00725941180.011
regulation of mapk cascadeGO:00434082480.011
cell growthGO:00160491300.011
myosin filament assemblyGO:003103420.011
nucleoside metabolic processGO:00091162460.011
negative regulation of t cell differentiationGO:0045581230.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
cellularizationGO:000734910.011
regulation of protein complex assemblyGO:0043254830.011
endothelial cell proliferationGO:0001935270.011
divalent inorganic cation transportGO:00725111780.011
protein secretionGO:00093061110.011
protein import into nucleusGO:0006606950.011
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.011
positive regulation of cellular protein catabolic processGO:1903364340.011
musculoskeletal movement spinal reflex actionGO:005088330.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
negative regulation of hydrolase activityGO:0051346710.011
negative regulation of cytoskeleton organizationGO:0051494360.011
cellular response to nutrient levelsGO:0031669640.011
cellular protein complex disassemblyGO:0043624360.011
single organism cell adhesionGO:00986021560.011
nuclear transportGO:00511691390.011
purine nucleoside monophosphate catabolic processGO:0009128580.011
organic hydroxy compound metabolic processGO:19016152030.011
positive regulation of dopamine uptake involved in synaptic transmissionGO:005158620.011
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:000008330.011
spermatid differentiationGO:00485151150.011
cellular protein catabolic processGO:00442571550.011
peptide secretionGO:00027901140.011
negative regulation of protein serine threonine kinase activityGO:0071901490.011
organism emergence from protective structureGO:007168440.011
regulation of mitosisGO:0007088290.010
positive regulation of cell activationGO:00508671580.010
ribonucleoside triphosphate catabolic processGO:00092031990.010
pallium developmentGO:00215431200.010
protein depolymerizationGO:0051261340.010
negative regulation of cell growthGO:0030308440.010
positive regulation of mitotic cell cycleGO:0045931410.010
regulation of wnt signaling pathwayGO:00301111230.010
positive regulation of proteolysisGO:0045862850.010
regulation of centriole replicationGO:004659910.010
regulation of synapse structural plasticityGO:005182340.010
ribonucleoside monophosphate metabolic processGO:0009161800.010
cellular response to antibioticGO:007123640.010
regulation of leukocyte proliferationGO:00706631210.010
nucleoside catabolic processGO:00091642060.010
regulation of apoptotic signaling pathwayGO:20012331970.010
maintenance of location in cellGO:0051651240.010
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.010
sequestering of metal ionGO:0051238190.010
regulation of anatomical structure sizeGO:00900661780.010
cell cycle arrestGO:0007050370.010
leukocyte migrationGO:00509001240.010
histone modificationGO:00165701590.010
maintenance of protein location in cellGO:0032507200.010
purine ribonucleoside triphosphate catabolic processGO:00092071990.010
meiosis iGO:0007127600.010
histone lysine methylationGO:0034968500.010
rho protein signal transductionGO:0007266320.010
purine nucleoside monophosphate metabolic processGO:0009126810.010

Tpx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.064
disease of cellular proliferationDOID:1456600.064
disease of anatomical entityDOID:700.059
hematopoietic system diseaseDOID:7400.059
immune system diseaseDOID:291400.059
organ system cancerDOID:005068600.030
thoracic cancerDOID:509300.015
breast cancerDOID:161200.015
nervous system diseaseDOID:86300.012
disease of metabolismDOID:001466700.010