Mus musculus

15 known processes

Pum2

pumilio 2 (Drosophila)

(Aliases: mKIAA0235,Pumm2,5730503J23Rik)

Pum2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of chromatin silencingGO:003193610.481
regulation of organelle organizationGO:00330432890.365
Worm
negative regulation of protein metabolic processGO:00512482820.285
histone modificationGO:00165701590.252
organelle assemblyGO:00709251770.220
cellular ketone metabolic processGO:0042180840.220
leukocyte differentiationGO:00025213420.208
stem cell developmentGO:00488642190.190
covalent chromatin modificationGO:00165691630.181
cellular macromolecule catabolic processGO:00442652060.177
macromolecule catabolic processGO:00090572810.165
chromatin modificationGO:00165681870.146
negative regulation of phosphate metabolic processGO:00459361840.145
Worm
regulation of cellular amine metabolic processGO:0033238200.138
circadian rhythmGO:00076231140.136
protein modification by small protein conjugationGO:00324461870.132
chromatin organizationGO:00063252060.132
cellular amino acid metabolic processGO:00065201030.130
small gtpase mediated signal transductionGO:0007264970.125
rna processingGO:00063961050.121
negative regulation of phosphorus metabolic processGO:00105631840.119
Worm
stem cell maintenanceGO:00198271300.119
rho protein signal transductionGO:0007266320.116
actin cytoskeleton organizationGO:00300362200.114
ras protein signal transductionGO:0007265770.108
protein modification by small protein conjugation or removalGO:00706472070.107
germ cell developmentGO:00072811850.106
protein localization to organelleGO:00333651850.105
positive regulation of organelle organizationGO:00106381280.097
regulation of cell cycleGO:00517262810.096
Worm
development of primary sexual characteristicsGO:00451371430.095
posttranscriptional regulation of gene expressionGO:00106081550.090
ubiquitin dependent protein catabolic processGO:00065111290.089
dendrite developmentGO:00163581150.089
Fly
negative regulation of cellular protein metabolic processGO:00322692470.088
protein acylationGO:0043543640.086
amine metabolic processGO:0009308450.083
circadian regulation of gene expressionGO:0032922480.082
protein localization to nucleusGO:00345041210.079
translationGO:0006412930.077
blood circulationGO:00080151950.077
aromatic compound catabolic processGO:00194392860.076
chromosome segregationGO:0007059480.076
protein polyubiquitinationGO:0000209330.072
regulation of intracellular transportGO:00323861590.072
cellular protein catabolic processGO:00442571550.071
protein ubiquitinationGO:00165671710.071
regulation of cellular amino acid metabolic processGO:000652150.070
regulation of circadian rhythmGO:0042752580.069
heterocycle catabolic processGO:00467002800.068
neural tube developmentGO:00219151600.066
meiotic cell cycle processGO:1903046770.064
rhythmic processGO:00485111740.064
response to molecule of bacterial originGO:00022371430.063
negative regulation of cellular amine metabolic processGO:003323910.063
organelle fissionGO:00482851700.062
Worm
digestive tract developmentGO:00485651900.062
histone lysine methylationGO:0034968500.060
striated muscle tissue developmentGO:00147062930.059
carbohydrate derivative catabolic processGO:19011362310.058
regulation of cellular ketone metabolic processGO:0010565660.058
membrane organizationGO:00610242450.057
positive regulation of mitotic cell cycleGO:0045931410.057
regulation of response to woundingGO:19030341890.056
angiogenesisGO:00015252010.055
microtubule based processGO:00070172360.054
negative regulation of phosphorylationGO:00423261660.054
Worm
female gamete generationGO:0007292740.054
negative regulation of cellular component organizationGO:00511291940.053
regulation of mapk cascadeGO:00434082480.053
Worm
gonad developmentGO:00084061410.052
blastocyst developmentGO:0001824800.052
mapk cascadeGO:00001652810.052
Worm
regulation of cytoskeleton organizationGO:00514931220.052
stem cell differentiationGO:00488632680.051
purine ribonucleotide metabolic processGO:00091502900.051
blood vessel morphogenesisGO:00485142850.050
actin filament based movementGO:0030048230.050
regulation of defense responseGO:00313472330.050
digestive system developmentGO:00551232000.050
organelle localizationGO:00516401790.049
tube formationGO:00351481400.049
modification dependent protein catabolic processGO:00199411330.049
regulation of establishment of protein localizationGO:00702011810.049
positive regulation of protein modification processGO:00314012990.048
nucleotide metabolic processGO:00091173320.048
heart contractionGO:0060047930.048
regulation of synaptic growth at neuromuscular junctionGO:000858240.048
Fly
limb developmentGO:00601731660.047
response to organonitrogen compoundGO:00102432460.047
proteolysis involved in cellular protein catabolic processGO:00516031470.047
carbohydrate derivative biosynthetic processGO:19011371830.047
regulation of protein stabilityGO:0031647520.047
morphogenesis of embryonic epitheliumGO:00163311590.046
epithelial tube morphogenesisGO:00605623030.046
heart processGO:0003015940.046
ribonucleoprotein complex subunit organizationGO:0071826280.045
ribonucleoside triphosphate metabolic processGO:00091992200.045
organic cyclic compound catabolic processGO:19013612950.045
regulation of chromatin silencingGO:003193520.044
oogenesisGO:0048477560.044
purine containing compound catabolic processGO:00725232130.042
regulation of chromatin organizationGO:1902275570.041
nuclear divisionGO:00002801580.041
Worm
primary neural tube formationGO:0014020950.041
myeloid cell differentiationGO:00300992330.041
regulation of ras protein signal transductionGO:00465781140.040
negative regulation of mapk cascadeGO:0043409650.040
Worm
multicellular organism growthGO:00352641610.040
circulatory system processGO:00030131970.039
ameboidal type cell migrationGO:00016671280.039
negative regulation of protein modification processGO:00314001630.038
negative regulation of peptidyl serine phosphorylationGO:0033137100.038
cytoplasmic transportGO:00164822340.038
cellular response to lipidGO:00713961450.038
ossificationGO:00015032160.038
negative regulation of chromatin modificationGO:1903309190.037
guanosine containing compound catabolic processGO:19010691440.037
response to lipopolysaccharideGO:00324961280.037
positive regulation of cell cycleGO:0045787920.036
regulation of cellular component sizeGO:00325351210.036
regulation of wnt signaling pathwayGO:00301111230.035
cytokine productionGO:00018163190.035
chemotaxisGO:00069352470.035
peptidyl amino acid modificationGO:00181933360.035
negative regulation of cell proliferationGO:00082852960.035
regulation of protein transportGO:00512231630.034
apical constrictionGO:000338340.034
meiotic cell cycleGO:00513211220.034
Worm
cell fate commitmentGO:00451652100.034
histone methylationGO:0016571710.034
response to organic cyclic compoundGO:00140701980.034
monosaccharide biosynthetic processGO:0046364440.034
limb morphogenesisGO:00351081490.034
cellular homeostasisGO:00197252400.034
meiotic nuclear divisionGO:00071261150.033
Worm
gastrulationGO:00073691160.033
negative regulation of wnt signaling pathwayGO:0030178730.032
wnt signaling pathwayGO:00160551880.032
regulation of protein kinase activityGO:00458592320.032
actin mediated cell contractionGO:0070252150.032
cellular nitrogen compound catabolic processGO:00442702800.032
establishment of planar polarityGO:0001736280.032
mrna metabolic processGO:0016071840.032
establishment of protein localization to organelleGO:00725941180.032
n terminal protein amino acid modificationGO:003136560.032
protein heterotrimerizationGO:007020880.032
purine containing compound metabolic processGO:00725213110.032
canonical wnt signaling pathwayGO:00600701300.031
purine nucleotide metabolic processGO:00061633020.031
regulation of cell substrate adhesionGO:0010810730.031
negative regulation of cell cycleGO:00457861230.031
regulation of apoptotic signaling pathwayGO:20012331970.031
sensory perceptionGO:00076002450.031
ribonucleotide catabolic processGO:00092612080.031
regulation of protein localizationGO:00328802310.031
embryonic skeletal system developmentGO:00487061200.031
regulation of purine nucleotide catabolic processGO:00331211220.031
epithelial tube formationGO:00721751300.030
male gamete generationGO:00482322850.030
Worm
skeletal system morphogenesisGO:00487052030.030
regulation of nucleoside metabolic processGO:00091181300.030
apoptotic signaling pathwayGO:00971903060.030
regulation of nucleotide metabolic processGO:00061401690.030
ribonucleoside metabolic processGO:00091192450.030
regulation of cellular catabolic processGO:00313292420.030
establishment of tissue polarityGO:0007164280.030
muscle cell differentiationGO:00426922610.030
microtubule cytoskeleton organizationGO:00002261570.030
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.030
tube closureGO:0060606910.029
positive regulation of nucleotide metabolic processGO:00459811140.029
negative regulation of intracellular signal transductionGO:19025321670.029
Worm
purine ribonucleoside catabolic processGO:00461302050.029
nuclear transportGO:00511691390.029
regulation of chromosome organizationGO:0033044830.029
intracellular protein transportGO:00068862040.029
regulation of hydrolase activityGO:00513362460.029
positive regulation of protein phosphorylationGO:00019342420.028
skeletal system developmentGO:00015013560.028
neural tube closureGO:0001843900.028
immune effector processGO:00022523210.028
mrna destabilizationGO:006115740.028
wound healingGO:00420601570.027
rna splicingGO:0008380540.027
phagocytosisGO:0006909660.027
neural tube formationGO:00018411080.027
rna phosphodiester bond hydrolysis exonucleolyticGO:009050340.027
regulation of kinase activityGO:00435492490.027
organonitrogen compound catabolic processGO:19015652640.027
appendage morphogenesisGO:00351071490.027
nucleoside phosphate metabolic processGO:00067533380.027
regulation of neuron differentiationGO:00456642810.026
positive regulation of cellular amine metabolic processGO:003324050.026
nucleoside catabolic processGO:00091642060.026
regulation of cell morphogenesis involved in differentiationGO:00107691510.025
cellular chemical homeostasisGO:00550822150.025
cellular response to hormone stimulusGO:00328701500.025
ribose phosphate metabolic processGO:00196932910.025
positive regulation of cell cycle processGO:0090068610.025
regulation of microtubule based processGO:0032886520.024
modification dependent macromolecule catabolic processGO:00436321330.024
peptidyl serine phosphorylationGO:0018105740.024
heart morphogenesisGO:00030071780.024
respiratory system developmentGO:00605411900.024
organophosphate catabolic processGO:00464342320.023
negative regulation of molecular functionGO:00440922580.023
endocytosisGO:00068971680.023
negative regulation of neuron deathGO:1901215980.023
spermatogenesisGO:00072832840.023
Worm
positive regulation of protein kinase activityGO:00458601440.023
cell cell junction organizationGO:0045216720.022
jnk cascadeGO:0007254720.022
regulation of nuclear divisionGO:0051783560.022
Worm
dna recombinationGO:0006310920.022
purine nucleoside catabolic processGO:00061522050.022
axon guidanceGO:00074111410.022
learning or memoryGO:00076111480.022
Fly
embryonic epithelial tube formationGO:00018381300.022
regulation of cell cycle processGO:00105641600.022
Worm
peptidyl serine modificationGO:0018209830.022
proteasomal protein catabolic processGO:0010498980.022
regulation of anatomical structure sizeGO:00900661780.021
purine nucleoside metabolic processGO:00422782410.021
fat cell differentiationGO:00454441600.021
embryonic appendage morphogenesisGO:00351131260.021
digestive tract morphogenesisGO:00485461470.021
i kappab kinase nf kappab signalingGO:0007249850.021
regulation of cellular carbohydrate metabolic processGO:0010675750.021
protein targetingGO:00066051430.021
lymphocyte differentiationGO:00300982420.021
neural precursor cell proliferationGO:00613511210.020
regulation of cytokine productionGO:00018172660.020
cell divisionGO:00513011200.020
Worm
regulation of protein localization to nucleusGO:1900180600.020
myeloid leukocyte differentiationGO:00025731190.020
neuron projection guidanceGO:00974851410.020
purine nucleoside triphosphate catabolic processGO:00091462030.020
regulation of cell adhesionGO:00301551540.019
protein alkylationGO:0008213810.019
inorganic cation transmembrane transportGO:00986622070.019
molting cycleGO:0042303900.019
meiotic chromosome segregationGO:0045132190.019
positive regulation of cellular amino acid metabolic processGO:004576430.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
protein methylationGO:0006479810.019
regulation of purine nucleotide metabolic processGO:19005421690.019
regulation of glucose metabolic processGO:0010906600.019
compound eye developmentGO:004874910.018
negative regulation of organelle organizationGO:0010639900.018
regulation of heart contractionGO:0008016770.018
regulation of cellular component biogenesisGO:00440871810.018
Fly
muscle tissue developmentGO:00605373080.018
mrna 3 end processingGO:0031124160.018
central nervous system neuron differentiationGO:00219531620.018
body morphogenesisGO:0010171450.018
mesoderm developmentGO:00074981000.018
establishment of organelle localizationGO:00516561220.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.018
Fly
regulation of cell migrationGO:00303342190.018
formation of primary germ layerGO:0001704770.018
regulation of translationGO:0006417710.018
forebrain developmentGO:00309003020.018
positive regulation of kinase activityGO:00336741550.018
regulation of membrane potentialGO:00423911920.018
lipid localizationGO:00108761260.018
embryonic limb morphogenesisGO:00303261260.018
negative regulation of gene silencingGO:006096920.018
protein catabolic processGO:00301632210.018
glucose homeostasisGO:00425931280.017
striated muscle contractionGO:0006941450.017
regulation of transferase activityGO:00513382630.017
negative regulation of cellular amino acid metabolic processGO:004576300.017
peptidyl lysine modificationGO:0018205770.017
multicellular organismal signalingGO:0035637910.017
oocyte axis specificationGO:000730920.017
regulation of cell projection organizationGO:00313442060.017
histone h4 k16 acetylationGO:004398430.017
muscle contractionGO:00069361010.017
chromatin silencing at rdnaGO:000018330.017
embryonic skeletal system morphogenesisGO:0048704910.017
mrna processingGO:0006397630.017
endomembrane system organizationGO:00102561470.017
multi organism behaviorGO:0051705620.017
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787250.017
appendage developmentGO:00487361660.017
homeostasis of number of cellsGO:00488722100.017
morphogenesis of a branching epitheliumGO:00611381930.017
cardiocyte differentiationGO:0035051870.017
rac protein signal transductionGO:0016601130.017
ribonucleotide metabolic processGO:00092592910.016
axonogenesisGO:00074092740.016
regulation of secretionGO:00510462740.016
regulation of planar cell polarity pathway involved in axis elongationGO:200004030.016
regulation of cell motilityGO:20001452360.016
nucleoside triphosphate catabolic processGO:00091432050.016
nucleoside metabolic processGO:00091162460.016
branching morphogenesis of an epithelial tubeGO:00487541590.016
connective tissue developmentGO:00614481790.016
cell type specific apoptotic processGO:00972852680.016
regulation of chromatin modificationGO:1903308570.016
cardiac muscle cell contractionGO:008600370.016
maintenance of locationGO:0051235890.016
bone morphogenesisGO:0060349780.016
positive regulation of intracellular transportGO:0032388700.016
spermatid differentiationGO:00485151150.016
regulation of microtubule cytoskeleton organizationGO:0070507370.016
regulation of cell sizeGO:0008361720.016
blastocyst formationGO:0001825330.016
multi multicellular organism processGO:00447061090.015
regulation of cytoplasmic mrna processing body assemblyGO:001060320.015
macromolecule methylationGO:00434141200.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.015
positive regulation of protein transportGO:0051222930.015
oocyte constructionGO:000730820.015
regulation of actin filament based processGO:0032970990.015
cartilage developmentGO:00512161400.015
cellular response to abiotic stimulusGO:0071214560.015
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
purine ribonucleoside triphosphate metabolic processGO:00092052200.015
negative regulation of protein phosphorylationGO:00019331260.015
nucleotide catabolic processGO:00091662170.015
actomyosin structure organizationGO:0031032560.015
regulation of gluconeogenesisGO:0006111300.015
cardiac muscle tissue developmentGO:00487381300.015
morphogenesis of a branching structureGO:00017632030.014
cardiac muscle contractionGO:0060048320.014
peptidyl lysine methylationGO:0018022290.014
neuron apoptotic processGO:00514021420.014
stress activated protein kinase signaling cascadeGO:0031098810.014
cation transmembrane transportGO:00986552660.014
centrosome organizationGO:0051297260.014
regulation of leukocyte differentiationGO:19021051590.014
nucleic acid phosphodiester bond hydrolysisGO:0090305490.014
regulation of ossificationGO:00302781120.014
regulation of cytoplasmic transportGO:19036491120.014
nucleocytoplasmic transportGO:00069131390.014
peptidyl lysine acetylationGO:0018394450.014
cytoplasmic mrna processing body assemblyGO:003396260.014
regulation of b cell activationGO:0050864810.014
cardiac muscle cell differentiationGO:0055007690.014
osteoclast differentiationGO:0030316620.014
regulation of protein complex assemblyGO:0043254830.014
cellular response to molecule of bacterial originGO:0071219830.014
neuron deathGO:00709971540.014
regulation of cell activationGO:00508652890.014
regulation of organ morphogenesisGO:20000271440.014
second messenger mediated signalingGO:0019932730.014
rna interferenceGO:001624620.014
response to oxygen levelsGO:0070482620.013
negative regulation of neuron apoptotic processGO:0043524920.013
mitotic sister chromatid cohesionGO:000706410.013
cellular glucose homeostasisGO:0001678520.013
cellular calcium ion homeostasisGO:00068741190.013
oxidation reduction processGO:00551143420.013
t cell differentiationGO:00302171740.013
camera type eye developmentGO:00430102660.013
activation of adenylate cyclase activityGO:000719040.013
regulation of myeloid leukocyte differentiationGO:0002761580.013
lung developmentGO:00303241640.013
cellular response to organonitrogen compoundGO:00714171450.013
gtp metabolic processGO:00460391440.013
negative regulation of cytokine productionGO:0001818840.013
plasma membrane organizationGO:0007009900.013
respiratory tube developmentGO:00303231670.013
negative regulation of translationGO:0017148220.013
mitotic cell cycleGO:00002781950.013
mitotic cell cycle processGO:19030471590.013
adherens junction assemblyGO:0034333220.013
v d j recombinationGO:0033151140.013
macromolecule deacylationGO:0098732370.013
positive regulation of nucleoside metabolic processGO:0045979910.013
carbohydrate homeostasisGO:00335001280.013
cellular amine metabolic processGO:0044106440.013
cellular response to lipopolysaccharideGO:0071222770.013
peptidyl threonine modificationGO:0018210310.013
cell maturationGO:00484691270.013
chromosome organization involved in meiosisGO:0070192390.013
adult behaviorGO:00305341350.012
Fly
positive regulation of neuron differentiationGO:00456661410.012
regulation of lymphocyte activationGO:00512492400.012
positive regulation of lymphocyte activationGO:00512511400.012
multi organism reproductive behaviorGO:0044705290.012
regulation of lymphocyte proliferationGO:00506701170.012
central nervous system neuron developmentGO:0021954670.012
locomotory behaviorGO:00076261950.012
protein glycosylationGO:0006486550.012
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.012
response to radiationGO:00093141650.012
nucleoside phosphate catabolic processGO:19012922220.012
response to drugGO:0042493750.012
mesoderm morphogenesisGO:0048332640.012
calcium ion homeostasisGO:00550741270.012
purine nucleotide catabolic processGO:00061952110.012
mitotic nuclear divisionGO:0007067480.012
protein import into nucleusGO:0006606950.012
purine ribonucleoside metabolic processGO:00461282410.012
regulation of carbohydrate metabolic processGO:0006109750.012
cell substrate junction assemblyGO:0007044240.012
skeletal muscle organ developmentGO:00605381630.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.012
bone developmentGO:00603481200.012
positive regulation of ossificationGO:0045778470.012
cellular protein complex assemblyGO:00436231160.012
inorganic ion transmembrane transportGO:00986602340.012
regulation of ion transmembrane transportGO:00347651190.012
anatomical structure homeostasisGO:00602491450.011
b cell activationGO:00421131610.011
epithelial cell developmentGO:00020641590.011
regulation of nucleocytoplasmic transportGO:0046822730.011
positive regulation of ras gtpase activityGO:0032320650.011
meiosis iGO:0007127600.011
internal peptidyl lysine acetylationGO:0018393420.011
glycosyl compound metabolic processGO:19016572460.011
somitogenesisGO:0001756690.011
stress activated mapk cascadeGO:0051403800.011
protein deacylationGO:0035601360.011
negative regulation of dna replicationGO:000815640.011
negative regulation of histone modificationGO:0031057180.011
single fertilizationGO:0007338820.011
gonad morphogenesisGO:003526210.011
response to amineGO:0014075160.011
fertilizationGO:00095661270.011
regulation of rho protein signal transductionGO:0035023710.011
ribonucleoside catabolic processGO:00424542060.011
regulation of canonical wnt signaling pathwayGO:0060828820.011
regulation of mrna processingGO:0050684410.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
phenol containing compound metabolic processGO:0018958600.011
regulation of system processGO:00440572000.011
regulation of ras gtpase activityGO:0032318880.011
corpus callosum morphogenesisGO:002154030.011
nucleobase containing small molecule metabolic processGO:00550863520.011
nucleus localizationGO:0051647200.011
positive regulation of cell developmentGO:00107202370.011
regulation of neuron projection developmentGO:00109751690.011
ion transmembrane transportGO:00342203610.011
rna catabolic processGO:0006401290.011
t cell activationGO:00421102890.011
cellular ion homeostasisGO:00068731650.011
sister chromatid cohesionGO:0007062120.011
camp metabolic processGO:0046058400.011
cell junction organizationGO:0034330770.010
positive regulation of nervous system developmentGO:00519622210.010
embryonic organ morphogenesisGO:00485622760.010
positive regulation of cell deathGO:00109422240.010
bmp signaling pathwayGO:0030509930.010
histone deacetylationGO:0016575260.010
cellular divalent inorganic cation homeostasisGO:00725031270.010
histone h4 acetylationGO:0043967100.010
positive regulation of myeloid cell differentiationGO:0045639430.010
regulation of protein serine threonine kinase activityGO:00719001570.010
mesoderm formationGO:0001707620.010
nuclear importGO:0051170950.010
metanephric loop of henle developmentGO:007223640.010
protein maturationGO:00516041760.010
regulation of dna endoreduplicationGO:003287530.010
lymphocyte proliferationGO:00466511640.010
regulation of protein catabolic processGO:00421761080.010
positive regulation of mapk cascadeGO:00434101700.010
trophectodermal cell differentiationGO:0001829210.010
positive regulation of protein serine threonine kinase activityGO:00719021060.010
regulation of intracellular protein transportGO:0033157820.010

Pum2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
congenital nervous system abnormalityDOID:249000.030
physical disorderDOID:008001500.030
disease of anatomical entityDOID:700.023
sensory system diseaseDOID:005015500.023
nervous system diseaseDOID:86300.023
eye and adnexa diseaseDOID:149200.021
eye diseaseDOID:561400.021
large intestine cancerDOID:567200.013
intestinal cancerDOID:1015500.013
gastrointestinal system cancerDOID:311900.013
cancerDOID:16200.013
colon cancerDOID:21900.013
disease of cellular proliferationDOID:1456600.013
organ system cancerDOID:005068600.013
colorectal cancerDOID:925600.013