Mus musculus

0 known processes

Wdr45

WD repeat domain 45

(Aliases: Wdrx1,C79260,DXImx38e,Sfc19,JM5)

Wdr45 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143420.522
autophagyGO:0006914450.157
Human
protein catabolic processGO:00301632210.118
cellular amino acid metabolic processGO:00065201030.116
regulation of cellular amino acid metabolic processGO:000652150.113
response to extracellular stimulusGO:00099911270.088
cellular ketone metabolic processGO:0042180840.086
macroautophagyGO:0016236210.085
cofactor metabolic processGO:0051186800.084
regulation of cellular ketone metabolic processGO:0010565660.080
dna metabolic processGO:00062593030.078
macromolecule catabolic processGO:00090572810.077
protein processingGO:00164851630.072
cation transportGO:00068123990.066
protein modification by small protein conjugation or removalGO:00706472070.063
cellular amine metabolic processGO:0044106440.063
dephosphorylationGO:00163111290.062
negative regulation of cell cycleGO:00457861230.061
protein maturationGO:00516041760.060
cellular lipid metabolic processGO:00442553230.059
cellular response to external stimulusGO:0071496880.058
membrane fusionGO:0061025380.055
cellular response to extracellular stimulusGO:0031668810.054
regulation of transcription from rna polymerase iii promoterGO:000635920.054
small molecule catabolic processGO:0044282710.054
proteolysis involved in cellular protein catabolic processGO:00516031470.052
regulation of cellular amine metabolic processGO:0033238200.050
regulation of cellular protein catabolic processGO:1903362610.049
amine metabolic processGO:0009308450.048
nitrogen compound transportGO:00717052710.047
regulation of cell cycleGO:00517262810.047
cellular lipid catabolic processGO:0044242520.047
positive regulation of cellular amino acid metabolic processGO:004576430.046
protein modification by small protein conjugationGO:00324461870.044
mitotic cell cycle processGO:19030471590.043
mitochondrion degradationGO:000042230.041
negative regulation of protein metabolic processGO:00512482820.040
regulation of bindingGO:00510981110.040
cellular macromolecule catabolic processGO:00442652060.040
negative regulation of cellular amine metabolic processGO:003323910.040
negative regulation of cellular component organizationGO:00511291940.040
regulation of protein maturationGO:1903317960.039
negative regulation of cellular amino acid metabolic processGO:004576300.039
positive regulation of dopamine secretionGO:003360320.038
regulation of intracellular transportGO:00323861590.037
spermatogenesisGO:00072832840.037
negative regulation of cellular protein metabolic processGO:00322692470.036
regulation of protein localizationGO:00328802310.036
cellular response to nutrient levelsGO:0031669640.036
positive regulation of cellular amine metabolic processGO:003324050.036
apoptotic signaling pathwayGO:00971903060.035
male gamete generationGO:00482322850.034
negative regulation of cell proliferationGO:00082852960.034
regulation of homeostatic processGO:00328441820.033
organelle fusionGO:0048284280.033
positive regulation of tor signalingGO:003200830.032
response to nutrient levelsGO:00316671090.032
negative regulation of protein modification processGO:00314001630.031
glucose homeostasisGO:00425931280.030
protein ubiquitinationGO:00165671710.030
modification dependent protein catabolic processGO:00199411330.029
membrane organizationGO:00610242450.029
mitotic cell cycleGO:00002781950.029
lateral inhibitionGO:004633110.028
regulation of cellular response to stressGO:00801351590.028
generation of precursor metabolites and energyGO:00060911030.028
ossificationGO:00015032160.028
cellular response to starvationGO:0009267570.027
positive regulation of cell deathGO:00109422240.027
regulation of mitotic cell cycleGO:00073461260.027
cellular protein catabolic processGO:00442571550.027
positive regulation of homeostatic processGO:0032846640.027
defense response to other organismGO:00985421970.026
regulation of apoptotic signaling pathwayGO:20012331970.026
modification dependent macromolecule catabolic processGO:00436321330.026
regulation of cellular component biogenesisGO:00440871810.026
water transportGO:0006833120.026
ubiquitin dependent protein catabolic processGO:00065111290.026
nucleotide metabolic processGO:00091173320.026
monocarboxylic acid catabolic processGO:0072329270.025
transcription from rna polymerase iii promoterGO:000638330.025
reactive nitrogen species metabolic processGO:200105700.025
positive regulation of catecholamine secretionGO:003360520.025
negative regulation of protein processingGO:0010955790.025
negative regulation of cellular catabolic processGO:0031330470.025
regulation of cell cycle phase transitionGO:1901987770.024
positive regulation of apoptotic processGO:00430652170.024
regulation of cellular catabolic processGO:00313292420.024
monocarboxylic acid metabolic processGO:00327871910.023
regulation of reactive oxygen species metabolic processGO:2000377400.023
regulation of protein transportGO:00512231630.023
lipid modificationGO:0030258650.023
negative regulation of phosphate metabolic processGO:00459361840.023
regulation of secretionGO:00510462740.023
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.022
regulation of hormone levelsGO:00108172110.022
regulation of ossificationGO:00302781120.022
negative regulation of apoptotic signaling pathwayGO:20012341040.021
regulation of organelle organizationGO:00330432890.021
visual behaviorGO:0007632450.021
organic acid catabolic processGO:0016054510.021
negative regulation of intracellular signal transductionGO:19025321670.021
homeostasis of number of cellsGO:00488722100.021
negative regulation of mitotic cell cycleGO:0045930580.021
response to starvationGO:0042594650.021
reactive oxygen species metabolic processGO:0072593840.021
fatty acid oxidationGO:0019395280.021
positive regulation of secretion by cellGO:19035321140.021
very long chain fatty acid catabolic processGO:004276020.020
peptidyl amino acid modificationGO:00181933360.020
positive regulation of protein phosphorylationGO:00019342420.020
maintenance of locationGO:0051235890.020
regulation of cell cycle processGO:00105641600.020
regulation of intracellular protein transportGO:0033157820.020
regulation of protein processingGO:0070613960.020
ras protein signal transductionGO:0007265770.020
negative regulation of protein maturationGO:1903318790.019
glucan metabolic processGO:0044042320.019
regulation of mapk cascadeGO:00434082480.019
regulation of secretion by cellGO:19035302490.019
regulation of vesicle mediated transportGO:00606271390.019
negative regulation of proteolysisGO:0045861740.019
carboxylic acid catabolic processGO:0046395510.019
retrograde transport endosome to golgiGO:004214720.019
cellular response to cytokine stimulusGO:00713451890.018
regulation of body fluid levelsGO:00508781620.018
cation transmembrane transportGO:00986552660.018
regulation of protein catabolic processGO:00421761080.018
cellular response to organonitrogen compoundGO:00714171450.018
t cell activationGO:00421102890.018
negative regulation of phosphorus metabolic processGO:00105631840.018
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.018
response to organic cyclic compoundGO:00140701980.018
endomembrane system organizationGO:00102561470.018
regulation of dephosphorylationGO:0035303180.017
germ line stem cell divisionGO:004207820.017
negative regulation of cell cycle phase transitionGO:1901988480.017
negative regulation of glycogen biosynthetic processGO:004571910.017
regulation of transferase activityGO:00513382630.017
positive regulation of secretionGO:00510471300.017
sperm motilityGO:0030317470.017
lipid biosynthetic processGO:00086101790.017
alpha amino acid metabolic processGO:1901605590.017
cellular response to oxidative stressGO:0034599760.017
immune effector processGO:00022523210.016
cellular carbohydrate metabolic processGO:00442621190.016
vacuole organizationGO:0007033380.016
cytoplasmic transportGO:00164822340.016
mitotic cytokinesisGO:000028140.016
regulation of membrane potentialGO:00423911920.016
neuron deathGO:00709971540.016
defense response to bacteriumGO:00427421190.016
energy derivation by oxidation of organic compoundsGO:0015980770.016
purine nucleotide metabolic processGO:00061633020.016
response to organonitrogen compoundGO:00102432460.015
ribonucleotide metabolic processGO:00092592910.015
establishment of protein localization to peroxisomeGO:007266340.015
rab protein signal transductionGO:003248210.015
negative regulation of cellular protein catabolic processGO:1903363220.015
regulation of osteoblast differentiationGO:0045667670.015
cellular chemical homeostasisGO:00550822150.015
regulation of proteolysisGO:00301621640.015
positive regulation of macroautophagyGO:001623930.015
renal water transportGO:000309760.015
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.015
cell type specific apoptotic processGO:00972852680.015
regulation of mitotic cell cycle phase transitionGO:1901990730.015
interspecies interaction between organismsGO:0044419830.015
mitochondrion organizationGO:00070051340.014
nucleobase containing small molecule metabolic processGO:00550863520.014
divalent metal ion transportGO:00708381720.014
methylationGO:00322591340.014
extracellular structure organizationGO:00430621480.014
response to endoplasmic reticulum stressGO:0034976530.014
metal ion homeostasisGO:00550651890.014
positive regulation of protein modification processGO:00314012990.014
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051220.014
response to light stimulusGO:00094161350.014
nucleoside phosphate metabolic processGO:00067533380.014
monoamine transportGO:0015844330.014
regulation of ion transportGO:00432692150.014
cellular metal ion homeostasisGO:00068751510.014
microtubule cytoskeleton organizationGO:00002261570.014
divalent inorganic cation transportGO:00725111780.013
negative regulation of cytokine productionGO:0001818840.013
purine ribonucleotide catabolic processGO:00091542080.013
negative regulation of mitotic cell cycle phase transitionGO:1901991450.013
regulation of kinase activityGO:00435492490.013
protein localization to organelleGO:00333651850.013
ear developmentGO:00435832000.013
negative regulation of cell cycle processGO:0010948690.013
dna recombinationGO:0006310920.013
anatomical structure homeostasisGO:00602491450.013
regulation of synaptic growth at neuromuscular junctionGO:000858240.013
response to oxygen levelsGO:0070482620.013
phospholipid metabolic processGO:0006644870.012
purine ribonucleoside triphosphate catabolic processGO:00092071990.012
carbohydrate homeostasisGO:00335001280.012
sequestering of metal ionGO:0051238190.012
protein secretionGO:00093061110.012
negative regulation of growthGO:0045926990.012
regulation of peptide transportGO:0090087910.012
negative regulation of phosphorylationGO:00423261660.012
organelle fissionGO:00482851700.012
regulation of hydrolase activityGO:00513362460.012
organonitrogen compound catabolic processGO:19015652640.012
negative regulation of nervous system developmentGO:00519611560.012
purine nucleoside metabolic processGO:00422782410.012
digestive tract morphogenesisGO:00485461470.012
response to radiationGO:00093141650.012
biomineral tissue developmentGO:0031214640.012
positive regulation of cellular catabolic processGO:00313311480.012
inorganic cation transmembrane transportGO:00986622070.012
g protein coupled receptor signaling pathwayGO:00071862430.012
action potentialGO:0001508780.012
microtubule based processGO:00070172360.012
protein kinase b signalingGO:0043491740.012
modification by host of symbiont morphology or physiologyGO:0051851120.012
sensory perceptionGO:00076002450.011
divalent inorganic cation homeostasisGO:00725071380.011
hematopoietic progenitor cell differentiationGO:00022441430.011
substantia nigra developmentGO:002176220.011
negative regulation of protein transportGO:0051224460.011
neuron apoptotic processGO:00514021420.011
regulation of establishment of protein localizationGO:00702011810.011
cell divisionGO:00513011200.011
chemotaxisGO:00069352470.011
endocytosisGO:00068971680.011
mitochondrial dna metabolic processGO:0032042130.011
cation homeostasisGO:00550802120.011
positive regulation of programmed cell deathGO:00430682180.011
cellular homeostasisGO:00197252400.011
organonitrogen compound biosynthetic processGO:19015661920.011
purine nucleoside catabolic processGO:00061522050.011
vitamin d3 metabolic processGO:007064030.011
lipid catabolic processGO:0016042690.011
regulation of cytoplasmic transportGO:19036491120.011
negative regulation of organelle organizationGO:0010639900.011
purine ribonucleotide metabolic processGO:00091502900.011
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.011
mapk cascadeGO:00001652810.011
aromatic compound catabolic processGO:00194392860.011
cellular glucose homeostasisGO:0001678520.011
skin developmentGO:00435882200.011
sensory perception of painGO:0019233470.011
positive regulation of hydrolase activityGO:00513451480.011
rhythmic processGO:00485111740.011
regulation of biomineral tissue developmentGO:0070167330.010
response to growth factorGO:00708481980.010
negative regulation of mitochondrion organizationGO:001082390.010
positive regulation of mitochondrial fissionGO:009014120.010
muscle cell differentiationGO:00426922610.010
regulation of protein serine threonine kinase activityGO:00719001570.010
hormone secretionGO:00468791280.010
insulin secretion involved in cellular response to glucose stimulusGO:0035773360.010
multicellular organismal signalingGO:0035637910.010
isoprenoid metabolic processGO:0006720290.010
response to molecule of bacterial originGO:00022371430.010
sterol homeostasisGO:0055092450.010
extrinsic apoptotic signaling pathwayGO:00971911260.010
calcium ion homeostasisGO:00550741270.010
regulation of protein bindingGO:0043393600.010
cellular response to dna damage stimulusGO:00069742070.010
cellular response to organic cyclic compoundGO:0071407870.010
innate immune responseGO:00450871570.010
muscle tissue developmentGO:00605373080.010
cytokine productionGO:00018163190.010
reactive oxygen species biosynthetic processGO:190340980.010

Wdr45 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.036
nervous system diseaseDOID:86300.016
central nervous system diseaseDOID:33100.016
disease of anatomical entityDOID:700.016
inherited metabolic disorderDOID:65500.013