Mus musculus

67 known processes

Gm2a

GM2 ganglioside activator protein

(Aliases: SAP-3,AA408702,AW215435,GM2-AP)

Gm2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
antigen processing and presentation of exogenous peptide antigenGO:0002478210.342
leukocyte mediated cytotoxicityGO:0001909620.293
myosin filament assemblyGO:003103420.088
antigen processing and presentation of peptide antigenGO:0048002290.073
organelle assemblyGO:00709251770.073
lymphocyte mediated immunityGO:00024491390.057
myosin filament organizationGO:003103330.057
organonitrogen compound catabolic processGO:19015652640.056
sphingolipid metabolic processGO:0006665450.056
t cell activationGO:00421102890.054
glycerolipid metabolic processGO:00464861220.050
metal ion homeostasisGO:00550651890.047
lytic vacuole organizationGO:0080171210.046
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.045
cell killingGO:0001906670.044
reactive oxygen species biosynthetic processGO:190340980.043
cellular amino acid metabolic processGO:00065201030.043
lipid biosynthetic processGO:00086101790.043
carbohydrate derivative catabolic processGO:19011362310.042
glycosyl compound catabolic processGO:19016582060.042
lysosome organizationGO:0007040210.041
oxidation reduction processGO:00551143420.041
nucleobase containing small molecule metabolic processGO:00550863520.041
ion transmembrane transportGO:00342203610.041
lipid localizationGO:00108761260.040
regulation of reactive oxygen species biosynthetic processGO:190342620.039
cellular amide metabolic processGO:0043603580.039
sphingolipid biosynthetic processGO:0030148260.039
hormone metabolic processGO:0042445860.039
purine ribonucleoside triphosphate catabolic processGO:00092071990.039
heterocycle catabolic processGO:00467002800.038
regulation of cellular catabolic processGO:00313292420.038
striated muscle myosin thick filament assemblyGO:007168810.038
cell adhesionGO:00071553290.038
amine metabolic processGO:0009308450.038
cation homeostasisGO:00550802120.037
transition metal ion transportGO:0000041380.037
antigen processing and presentation of exogenous antigenGO:0019884260.036
adaptive immune responseGO:00022501550.036
nucleoside phosphate metabolic processGO:00067533380.036
positive regulation of natural killer cell mediated immunityGO:0002717160.035
macromolecule catabolic processGO:00090572810.035
actin cytoskeleton organizationGO:00300362200.035
aromatic compound catabolic processGO:00194392860.035
positive regulation of t cell mediated cytotoxicityGO:0001916150.035
nucleotide metabolic processGO:00091173320.034
t cell mediated cytotoxicityGO:0001913260.034
regulation of apoptotic signaling pathwayGO:20012331970.033
transmembrane transportGO:00550854120.033
antigen processing and presentationGO:0019882470.033
membrane lipid biosynthetic processGO:0046467320.032
cellular protein complex assemblyGO:00436231160.032
positive regulation of lymphocyte activationGO:00512511400.031
response to organic cyclic compoundGO:00140701980.031
negative regulation of cell proliferationGO:00082852960.031
lipid transportGO:0006869980.030
reactive nitrogen species metabolic processGO:200105700.030
positive regulation of apoptotic signaling pathwayGO:2001235950.030
membrane lipid metabolic processGO:0006643530.029
ribonucleotide metabolic processGO:00092592910.029
posttranscriptional regulation of gene expressionGO:00106081550.029
nucleoside catabolic processGO:00091642060.029
positive regulation of innate immune responseGO:0045089800.029
apoptotic signaling pathwayGO:00971903060.029
cellular component assembly involved in morphogenesisGO:00109271390.029
sulfur compound metabolic processGO:00067901000.028
ribonucleoside metabolic processGO:00091192450.028
ribonucleoside triphosphate catabolic processGO:00092031990.028
purine nucleoside metabolic processGO:00422782410.027
endocytosisGO:00068971680.027
organic anion transportGO:00157111370.027
cellular amine metabolic processGO:0044106440.027
purine nucleotide metabolic processGO:00061633020.027
nucleoside metabolic processGO:00091162460.027
angiogenesisGO:00015252010.027
regulation of hydrolase activityGO:00513362460.027
monocarboxylic acid metabolic processGO:00327871910.027
regulation of lymphocyte activationGO:00512492400.026
glycosyl compound metabolic processGO:19016572460.026
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.026
fatty acid metabolic processGO:00066311210.025
alcohol metabolic processGO:00060661160.025
ribonucleotide catabolic processGO:00092612080.025
cation transportGO:00068123990.025
regulation of t cell activationGO:00508631700.025
regulation of transferase activityGO:00513382630.025
cellular homeostasisGO:00197252400.024
glycosphingolipid catabolic processGO:004647950.024
ceramide metabolic processGO:0006672310.024
response to peptideGO:19016521360.024
organonitrogen compound biosynthetic processGO:19015661920.024
carbohydrate metabolic processGO:00059752300.024
ribonucleoside catabolic processGO:00424542060.023
reactive oxygen species metabolic processGO:0072593840.023
monosaccharide metabolic processGO:00059961060.023
regulation of reactive oxygen species metabolic processGO:2000377400.023
purine ribonucleoside catabolic processGO:00461302050.023
leukocyte mediated immunityGO:00024431740.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.023
maintenance of locationGO:0051235890.023
negative regulation of protein metabolic processGO:00512482820.023
multicellular organismal homeostasisGO:00488711640.023
regulation of cellular amino acid metabolic processGO:000652150.022
positive regulation of reactive oxygen species biosynthetic processGO:190342820.022
antigen processing and presentation of peptide antigen via mhc class iGO:000247490.022
antigen processing and presentation of endogenous peptide antigen via mhc class iGO:001988530.022
amino acid transportGO:0006865610.022
cellular lipid metabolic processGO:00442553230.022
regulation of lipid metabolic processGO:00192161180.022
triglyceride metabolic processGO:0006641510.022
regulation of cell activationGO:00508652890.022
glycoprotein metabolic processGO:00091001160.022
lung developmentGO:00303241640.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.021
cellular nitrogen compound catabolic processGO:00442702800.021
respiratory tube developmentGO:00303231670.021
carboxylic acid transportGO:00469421000.021
negative regulation of cell activationGO:00508661110.021
anion transportGO:00068201770.021
ceramide biosynthetic processGO:0046513200.021
skeletal system developmentGO:00015013560.021
purine ribonucleotide metabolic processGO:00091502900.020
lateral inhibitionGO:004633110.020
natural killer cell mediated immunityGO:0002228290.020
cellular response to organonitrogen compoundGO:00714171450.020
sterol metabolic processGO:0016125580.020
nucleotide catabolic processGO:00091662170.020
carbohydrate homeostasisGO:00335001280.020
nucleoside phosphate catabolic processGO:19012922220.020
organic acid transportGO:00158491010.020
cellular metal ion homeostasisGO:00068751510.020
lymphocyte proliferationGO:00466511640.020
membrane organizationGO:00610242450.020
inflammatory responseGO:00069542440.020
purine containing compound metabolic processGO:00725213110.020
purine ribonucleoside metabolic processGO:00461282410.020
neuronal action potentialGO:0019228540.020
cation transmembrane transportGO:00986552660.020
nucleoside triphosphate metabolic processGO:00091412300.019
ribonucleoside triphosphate metabolic processGO:00091992200.019
nucleoside monophosphate metabolic processGO:0009123850.019
neutral lipid metabolic processGO:0006638570.019
respiratory system developmentGO:00605411900.019
ear developmentGO:00435832000.019
negative regulation of cellular protein metabolic processGO:00322692470.019
hexose metabolic processGO:0019318980.019
ribose phosphate metabolic processGO:00196932910.019
regulation of adaptive immune responseGO:0002819900.018
regulation of leukocyte mediated cytotoxicityGO:0001910380.018
protein catabolic processGO:00301632210.018
regulation of leukocyte mediated immunityGO:00027031040.018
male gamete generationGO:00482322850.018
hematopoietic progenitor cell differentiationGO:00022441430.018
lipid catabolic processGO:0016042690.018
purine nucleoside triphosphate metabolic processGO:00091442260.017
t cell mediated immunityGO:0002456500.017
organic cyclic compound catabolic processGO:19013612950.017
rho protein signal transductionGO:0007266320.017
organic acid catabolic processGO:0016054510.017
regulation of lymphocyte mediated immunityGO:0002706840.017
lipid modificationGO:0030258650.017
peptidyl amino acid modificationGO:00181933360.017
cellular ketone metabolic processGO:0042180840.017
lymphocyte activation involved in immune responseGO:0002285930.017
response to organonitrogen compoundGO:00102432460.016
immune effector processGO:00022523210.016
organophosphate catabolic processGO:00464342320.016
macromolecule glycosylationGO:0043413550.016
small molecule catabolic processGO:0044282710.016
positive regulation of apoptotic processGO:00430652170.016
regulation of hormone levelsGO:00108172110.016
purine nucleoside triphosphate catabolic processGO:00091462030.016
small molecule biosynthetic processGO:00442831320.016
innate immune responseGO:00450871570.016
intracellular cholesterol transportGO:003236730.016
cellular chemical homeostasisGO:00550822150.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
response to extracellular stimulusGO:00099911270.016
purine nucleoside catabolic processGO:00061522050.016
dephosphorylationGO:00163111290.016
iron ion import into cellGO:009745940.015
muscle cell differentiationGO:00426922610.015
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathwayGO:000248430.015
vacuole organizationGO:0007033380.015
cellular modified amino acid metabolic processGO:0006575630.015
nucleoside triphosphate catabolic processGO:00091432050.015
positive regulation of cellular amino acid metabolic processGO:004576430.015
locomotory behaviorGO:00076261950.015
regulation of cellular ketone metabolic processGO:0010565660.015
multicellular organismal iron ion homeostasisGO:006058680.015
nitrogen compound transportGO:00717052710.015
antigen processing and presentation of exogenous peptide antigen via mhc class iiGO:0019886140.014
intracellular protein transportGO:00068862040.014
response to molecule of bacterial originGO:00022371430.014
organic hydroxy compound transportGO:0015850930.014
regulation of membrane potentialGO:00423911920.014
single organism cell adhesionGO:00986021560.014
production of molecular mediator of immune responseGO:00024401030.014
sodium ion transmembrane transportGO:0035725490.014
lipid homeostasisGO:0055088630.014
regulation of mapk cascadeGO:00434082480.014
regulation of cellular amine metabolic processGO:0033238200.014
atp catabolic processGO:0006200550.014
regulation of defense responseGO:00313472330.014
positive regulation of lymphocyte mediated immunityGO:0002708620.014
regulation of t cell mediated cytotoxicityGO:0001914180.014
epithelial cell proliferationGO:00506731740.014
cellular lipid catabolic processGO:0044242520.014
glycosylceramide metabolic processGO:000667740.014
carbohydrate derivative biosynthetic processGO:19011371830.014
facioacoustic ganglion developmentGO:190337530.014
cellular divalent inorganic cation homeostasisGO:00725031270.013
positive regulation of programmed cell deathGO:00430682180.013
sphingolipid catabolic processGO:003014970.013
negative regulation of cellular component organizationGO:00511291940.013
organophosphate ester transportGO:0015748280.013
natural killer cell mediated cytotoxicityGO:0042267290.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
intracellular sterol transportGO:003236630.013
purine ribonucleotide catabolic processGO:00091542080.013
multicellular organismal signalingGO:0035637910.013
positive regulation of protein modification processGO:00314012990.013
regulation of system processGO:00440572000.013
actomyosin structure organizationGO:0031032560.013
response to nutrient levelsGO:00316671090.013
multicellular organism growthGO:00352641610.013
sequestering of metal ionGO:0051238190.013
cellular ion homeostasisGO:00068731650.013
fat cell differentiationGO:00454441600.013
glucose homeostasisGO:00425931280.013
purine containing compound catabolic processGO:00725232130.013
regulation of nucleotide metabolic processGO:00061401690.013
wound healingGO:00420601570.013
organelle localizationGO:00516401790.012
regulation of proteolysisGO:00301621640.012
intracellular lipid transportGO:003236530.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
positive regulation of membrane protein ectodomain proteolysisGO:005104430.012
lymphocyte differentiationGO:00300982420.012
regulation of lymphocyte differentiationGO:00456191070.012
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.012
mrna metabolic processGO:0016071840.012
positive regulation of cell adhesionGO:0045785800.012
collagen metabolic processGO:0032963170.012
cellular macromolecule catabolic processGO:00442652060.012
engulfment of apoptotic cellGO:004365230.012
cellular response to hormone stimulusGO:00328701500.012
guanosine containing compound metabolic processGO:19010681440.012
regulation of gamma aminobutyric acid secretionGO:001405220.012
cellular response to lipidGO:00713961450.012
synaptic vesicle localizationGO:0097479590.012
regulation of kinase activityGO:00435492490.012
regulation of peptidase activityGO:0052547960.012
alpha beta t cell activationGO:0046631910.012
calcium ion transportGO:00068161590.012
action potentialGO:0001508780.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
positive regulation of t cell activationGO:00508701010.012
leukocyte activation involved in immune responseGO:00023661260.012
positive regulation of adaptive immune responseGO:0002821610.012
regulation of secretionGO:00510462740.012
cellular response to thyroid hormone stimulusGO:009706710.011
carboxylic acid biosynthetic processGO:0046394860.011
purine nucleoside monophosphate catabolic processGO:0009128580.011
cellular protein catabolic processGO:00442571550.011
organic acid biosynthetic processGO:0016053860.011
positive regulation of hydrolase activityGO:00513451480.011
multi multicellular organism processGO:00447061090.011
leukocyte proliferationGO:00706611720.011
regulation of protein kinase activityGO:00458592320.011
regulation of systemic arterial blood pressure by carotid body chemoreceptor signalingGO:000302710.011
brown fat cell differentiationGO:0050873360.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
ossificationGO:00015032160.011
phagolysosome assemblyGO:000184530.011
striated muscle cell developmentGO:00550021250.011
membrane protein proteolysisGO:0033619100.011
ear morphogenesisGO:00424711180.011
cell activation involved in immune responseGO:00022631260.011
negative regulation of intracellular signal transductionGO:19025321670.011
mitochondrion organizationGO:00070051340.011
myelinationGO:0042552740.011
steroid metabolic processGO:00082021190.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
sterol transportGO:0015918380.011
response to starvationGO:0042594650.011
actin polymerization or depolymerizationGO:0008154540.011
regulation of neurotransmitter levelsGO:0001505870.011
carboxylic acid catabolic processGO:0046395510.011
small gtpase mediated signal transductionGO:0007264970.011
purine nucleotide catabolic processGO:00061952110.011
ceramide catabolic processGO:004651470.011
regulation of cellular response to stressGO:00801351590.010
activation of immune responseGO:00022531380.010
regulation of cell adhesionGO:00301551540.010
regulation of leukocyte differentiationGO:19021051590.010
negative regulation of proteolysisGO:0045861740.010
semaphorin plexin signaling pathway involved in bone trabecula morphogenesisGO:190022020.010
acylglycerol metabolic processGO:0006639550.010
regulation of vesicle mediated transportGO:00606271390.010
muscle tissue developmentGO:00605373080.010
germ cell developmentGO:00072811850.010
mapk cascadeGO:00001652810.010
positive regulation of transferase activityGO:00513471670.010
methylationGO:00322591340.010
transition metal ion homeostasisGO:0055076540.010
axonogenesisGO:00074092740.010
proteoglycan metabolic processGO:0006029380.010
regulation of neuron projection developmentGO:00109751690.010
phagosome maturationGO:009038240.010
negative regulation of growthGO:0045926990.010
positive regulation of cytokine productionGO:00018191740.010
protein digestionGO:004425610.010
positive regulation of cell deathGO:00109422240.010
epidermis developmentGO:00085441870.010
positive regulation of natural killer cell mediated cytotoxicityGO:0045954160.010
sensory perceptionGO:00076002450.010

Gm2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.474
Human
disease of metabolismDOID:001466700.474
Human
nervous system diseaseDOID:86300.136
Human
central nervous system diseaseDOID:33100.136
Human
disease of anatomical entityDOID:700.136
Human
retinal diseaseDOID:567900.054
sensory system diseaseDOID:005015500.054
eye and adnexa diseaseDOID:149200.054
eye diseaseDOID:561400.054
lipid storage diseaseDOID:945500.043
Human
lysosomal storage diseaseDOID:321100.043
Human
brain diseaseDOID:93600.037
Human
sphingolipidosisDOID:192700.033
Human
immune system diseaseDOID:291400.030
cerebral degenerationDOID:144300.022
Human
neurodegenerative diseaseDOID:128900.017
retinal degenerationDOID:846600.013
disease of mental healthDOID:15000.011