IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Diras1

DIRAS family, GTP-binding RAS-like 1

(Aliases: RIG,Di-Ras1,Gbts1)

Ensembl: ENSMUSG00000043670
Entrez: 208666
UniProtKB: Q91Z61

Process Predictions
Disease Predictions

Diras1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cation transport	GO:0006812	399	0.430
synaptic transmission	GO:0007268	329	0.389
positive regulation of nervous system development	GO:0051962	221	0.338
regulation of membrane potential	GO:0042391	192	0.331
cation transmembrane transport	GO:0098655	266	0.216
transmission of nerve impulse	GO:0019226	76	0.207
neuronal action potential	GO:0019228	54	0.201
cellular amine metabolic process	GO:0044106	44	0.200
conditioned taste aversion	GO:0001661	4	0.186
regulation of cellular amino acid metabolic process	GO:0006521	5	0.184
synapse organization	GO:0050808	125	0.183
ion transmembrane transport	GO:0034220	361	0.170
dendrite development	GO:0016358	115	0.164
memory	GO:0007613	58	0.149
regulation of cellular component size	GO:0032535	121	0.148
locomotory behavior	GO:0007626	195	0.145
amine metabolic process	GO:0009308	45	0.135
axonogenesis	GO:0007409	274	0.133
membrane depolarization	GO:0051899	64	0.131
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.130
positive regulation of protein modification process	GO:0031401	299	0.125	Mouse
regulation of mapk cascade	GO:0043408	248	0.123
calcium ion transport	GO:0006816	159	0.123
divalent metal ion transport	GO:0070838	172	0.122
calcium ion transmembrane transport	GO:0070588	85	0.120
regulation of ion transport	GO:0043269	215	0.118
membrane organization	GO:0061024	245	0.115
regulation of cell projection organization	GO:0031344	206	0.115
transmembrane transport	GO:0055085	412	0.115
regulation of transferase activity	GO:0051338	263	0.112	Mouse
nucleoside phosphate catabolic process	GO:1901292	222	0.109	Human Yeast
positive regulation of protein phosphorylation	GO:0001934	242	0.109	Mouse
developmental growth involved in morphogenesis	GO:0060560	138	0.107
regulation of cell migration	GO:0030334	219	0.107	Mouse
negative regulation of cell proliferation	GO:0008285	296	0.104
mapk cascade	GO:0000165	281	0.104
hindbrain development	GO:0030902	128	0.100
regulation of cell motility	GO:2000145	236	0.091	Mouse
learning or memory	GO:0007611	148	0.090
divalent inorganic cation transport	GO:0072511	178	0.087
sensory perception	GO:0007600	245	0.086
cognition	GO:0050890	149	0.084
cellular ketone metabolic process	GO:0042180	84	0.083
multicellular organismal signaling	GO:0035637	91	0.082
regulation of cell size	GO:0008361	72	0.080
developmental cell growth	GO:0048588	84	0.080
action potential	GO:0001508	78	0.080
glial cell differentiation	GO:0010001	131	0.079
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.078
inorganic ion transmembrane transport	GO:0098660	234	0.075
cytokine production	GO:0001816	319	0.074
adult behavior	GO:0030534	135	0.072
retina development in camera type eye	GO:0060041	119	0.072
regulation of cell activation	GO:0050865	289	0.070
regulation of cellular amine metabolic process	GO:0033238	20	0.069
inorganic cation transmembrane transport	GO:0098662	207	0.068
protein localization to membrane	GO:0072657	108	0.066
positive regulation of cell development	GO:0010720	237	0.063
fat cell differentiation	GO:0045444	160	0.063
g protein coupled receptor signaling pathway	GO:0007186	243	0.062
regulation of secretion by cell	GO:1903530	249	0.062
regulation of cellular ketone metabolic process	GO:0010565	66	0.061
membrane hyperpolarization	GO:0060081	21	0.060
regulation of neuron differentiation	GO:0045664	281	0.059
positive regulation of cellular amine metabolic process	GO:0033240	5	0.059
sensory perception of mechanical stimulus	GO:0050954	107	0.058
epidermis development	GO:0008544	187	0.058
detection of mechanical stimulus involved in sensory perception	GO:0050974	23	0.058
chemotaxis	GO:0006935	247	0.058
epithelial cell development	GO:0002064	159	0.056
learning	GO:0007612	98	0.054
sodium ion transport	GO:0006814	73	0.053
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	GO:0001988	1	0.053
positive regulation of cell motility	GO:2000147	116	0.053
regulation of engulfment of apoptotic cell	GO:1901074	2	0.053
regulation of system process	GO:0044057	200	0.052
negative regulation of action potential	GO:0045759	1	0.052
heterocycle catabolic process	GO:0046700	280	0.052	Human Yeast
regulation of anatomical structure size	GO:0090066	178	0.052
regulation of protein kinase activity	GO:0045859	232	0.051	Mouse
positive regulation of growth	GO:0045927	104	0.051
camera type eye development	GO:0043010	266	0.050
detection of mechanical stimulus	GO:0050982	27	0.050
striated muscle contraction	GO:0006941	45	0.050
sensory perception of sound	GO:0007605	97	0.049
purine ribonucleotide catabolic process	GO:0009154	208	0.048	Human Yeast
inflammatory response	GO:0006954	244	0.048
forebrain development	GO:0030900	302	0.048
telencephalon cell migration	GO:0022029	55	0.047
potassium ion transport	GO:0006813	52	0.047
sensory organ morphogenesis	GO:0090596	242	0.047
regulation of inflammatory response	GO:0050727	147	0.047
muscle contraction	GO:0006936	101	0.047
ear development	GO:0043583	200	0.047
aromatic compound catabolic process	GO:0019439	286	0.047	Human Yeast
cell growth	GO:0016049	130	0.046
nucleotide catabolic process	GO:0009166	217	0.046	Human Yeast
myelination	GO:0042552	74	0.046
sperm motility	GO:0030317	47	0.046
positive regulation of mapk cascade	GO:0043410	170	0.045
purine containing compound catabolic process	GO:0072523	213	0.044	Human Yeast
neuron neuron synaptic transmission	GO:0007270	69	0.044
intracellular protein transport	GO:0006886	204	0.044
regulation of transporter activity	GO:0032409	57	0.044
microtubule cytoskeleton organization	GO:0000226	157	0.044
metencephalon development	GO:0022037	89	0.044
regulation of organelle organization	GO:0033043	289	0.043
peptidyl amino acid modification	GO:0018193	336	0.043	Mouse
regulation of acetylcholine secretion neurotransmission	GO:0014056	2	0.043
regulation of excitatory postsynaptic membrane potential	GO:0060079	41	0.043
neuron projection guidance	GO:0097485	141	0.043
regulation of voltage gated calcium channel activity	GO:1901385	4	0.043
adult locomotory behavior	GO:0008344	91	0.043
cellular nitrogen compound catabolic process	GO:0044270	280	0.042	Human Yeast
heart contraction	GO:0060047	93	0.042
regulation of neuron projection development	GO:0010975	169	0.042
organic hydroxy compound metabolic process	GO:1901615	203	0.041
detection of stimulus	GO:0051606	84	0.041
cerebellar purkinje cell layer development	GO:0021680	26	0.041
central nervous system neuron differentiation	GO:0021953	162	0.041
negative regulation of cellular protein metabolic process	GO:0032269	247	0.040
synapse assembly	GO:0007416	56	0.040
regulation of cellular component biogenesis	GO:0044087	181	0.040
regulation of cytokine production	GO:0001817	266	0.040
regulation of secretion	GO:0051046	274	0.039
fertilization	GO:0009566	127	0.038
negative regulation of intracellular signal transduction	GO:1902532	167	0.037
muscle system process	GO:0003012	141	0.037
telencephalon development	GO:0021537	186	0.036
regulation of wnt signaling pathway	GO:0030111	123	0.036
male gamete generation	GO:0048232	285	0.036
positive regulation of neuron projection development	GO:0010976	79	0.036
neuromuscular process	GO:0050905	99	0.036
anion transport	GO:0006820	177	0.035
germ cell development	GO:0007281	185	0.035
feeding behavior	GO:0007631	62	0.035
regulation of defense response	GO:0031347	233	0.035
blood circulation	GO:0008015	195	0.035
nucleobase containing small molecule metabolic process	GO:0055086	352	0.035	Human Yeast
organic cyclic compound catabolic process	GO:1901361	295	0.035	Human Yeast
negative regulation of cell differentiation involved in embryonic placenta development	GO:0060806	1	0.035
fatty acid metabolic process	GO:0006631	121	0.035
purine nucleotide metabolic process	GO:0006163	302	0.034	Human Yeast
positive regulation of cell projection organization	GO:0031346	95	0.034
carbohydrate derivative catabolic process	GO:1901136	231	0.034	Human Yeast
globus pallidus development	GO:0021759	2	0.034
forebrain cell migration	GO:0021885	58	0.034
divalent inorganic cation homeostasis	GO:0072507	138	0.034
hair follicle development	GO:0001942	85	0.034
neuron projection extension	GO:1990138	64	0.033
negative regulation of cellular component organization	GO:0051129	194	0.033
negative regulation of protein metabolic process	GO:0051248	282	0.033
sensory perception of light stimulus	GO:0050953	54	0.033
engulfment of apoptotic cell	GO:0043652	3	0.033
response to radiation	GO:0009314	165	0.032
positive regulation of high voltage gated calcium channel activity	GO:1901843	1	0.032
leukocyte migration	GO:0050900	124	0.032
cellular chemical homeostasis	GO:0055082	215	0.032
negative regulation of neuron apoptotic process	GO:0043524	92	0.031
heart process	GO:0003015	94	0.031
cellular calcium ion homeostasis	GO:0006874	119	0.031
epithalamus development	GO:0021538	2	0.031
positive regulation of protein kinase activity	GO:0045860	144	0.031
dopamine metabolic process	GO:0042417	23	0.031
nucleoside triphosphate metabolic process	GO:0009141	230	0.031	Human Yeast
regulation of ion transmembrane transport	GO:0034765	119	0.030
hindbrain morphogenesis	GO:0021575	46	0.030
amino acid transport	GO:0006865	61	0.030
negative regulation of molecular function	GO:0044092	258	0.030
peptidyl serine modification	GO:0018209	83	0.030
protein kinase b signaling	GO:0043491	74	0.029
menarche	GO:0042696	1	0.029
neuromuscular synaptic transmission	GO:0007274	16	0.029
nitrogen compound transport	GO:0071705	271	0.029
cell recognition	GO:0008037	83	0.029
inner ear morphogenesis	GO:0042472	101	0.029
detection of abiotic stimulus	GO:0009582	60	0.029
positive regulation of heart rate	GO:0010460	10	0.029
skin development	GO:0043588	220	0.029
developmental maturation	GO:0021700	193	0.028
detection of external stimulus	GO:0009581	61	0.028
detection of molecule of bacterial origin	GO:0032490	2	0.028
norepinephrine transport	GO:0015874	2	0.028
t cell activation	GO:0042110	289	0.028
macromolecule catabolic process	GO:0009057	281	0.028
regulation of postsynaptic membrane potential	GO:0060078	48	0.028
regulation of kinase activity	GO:0043549	249	0.028	Mouse
regulation of protein serine threonine kinase activity	GO:0071900	157	0.027
activation of immune response	GO:0002253	138	0.027
associative learning	GO:0008306	61	0.027
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.027
epithelial cell migration	GO:0010631	63	0.027
regulation of dopamine secretion	GO:0014059	9	0.027
endomembrane system organization	GO:0010256	147	0.027
regulation of muscle contraction	GO:0006937	49	0.026
cellular response to hormone stimulus	GO:0032870	150	0.026
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.026
positive regulation of secretion	GO:0051047	130	0.026
neuron migration	GO:0001764	122	0.026
oxidation reduction process	GO:0055114	342	0.026
neural retina development	GO:0003407	41	0.025
neuron death	GO:0070997	154	0.025
regulation of response to wounding	GO:1903034	189	0.025
regulation of saliva secretion	GO:0046877	2	0.025
positive regulation of kinase activity	GO:0033674	155	0.024
regulation of extent of cell growth	GO:0061387	52	0.024
ribonucleotide metabolic process	GO:0009259	291	0.024	Human Yeast
regulation of metal ion transport	GO:0010959	106	0.024
cellular protein complex disassembly	GO:0043624	36	0.024
axon guidance	GO:0007411	141	0.024
neural nucleus development	GO:0048857	22	0.024
ear morphogenesis	GO:0042471	118	0.024
multicellular organism growth	GO:0035264	161	0.024
stem cell differentiation	GO:0048863	268	0.024
cellular homeostasis	GO:0019725	240	0.024
axon ensheathment	GO:0008366	76	0.024
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.024
response to organonitrogen compound	GO:0010243	246	0.023
cell division	GO:0051301	120	0.023
exploration behavior	GO:0035640	21	0.023
neurotransmitter transport	GO:0006836	76	0.023
glutamate receptor signaling pathway	GO:0007215	35	0.023
purine nucleoside catabolic process	GO:0006152	205	0.023	Human Yeast
nucleoside triphosphate catabolic process	GO:0009143	205	0.023	Human Yeast
response to glycoside	GO:1903416	2	0.023
phagocytosis	GO:0006909	66	0.023
regulation of heart contraction	GO:0008016	77	0.023
gland development	GO:0048732	330	0.023
nucleoside monophosphate metabolic process	GO:0009123	85	0.023
regulation of neurotransmitter levels	GO:0001505	87	0.023
olfactory learning	GO:0008355	2	0.023
regulation of transmembrane transport	GO:0034762	128	0.023
regulation of protein depolymerization	GO:1901879	26	0.022
baroreceptor response to decreased systemic arterial blood pressure	GO:0001982	2	0.022
regulation of ion transmembrane transporter activity	GO:0032412	54	0.022
cellular amino acid metabolic process	GO:0006520	103	0.022
regulation of glutamate secretion	GO:0014048	3	0.022
regionalization	GO:0003002	337	0.022
regulation of vesicle mediated transport	GO:0060627	139	0.022
muscle tissue development	GO:0060537	308	0.022
protein complex disassembly	GO:0043241	40	0.022
nuclear division	GO:0000280	158	0.022
organic anion transport	GO:0015711	137	0.021
carbohydrate metabolic process	GO:0005975	230	0.021
cerebral cortex cell migration	GO:0021795	44	0.021
astrocyte differentiation	GO:0048708	43	0.021
cellular response to lipid	GO:0071396	145	0.021
positive regulation of voltage gated calcium channel activity	GO:1901387	2	0.021
protein catabolic process	GO:0030163	221	0.021
positive regulation of neuron differentiation	GO:0045666	141	0.021
cell adhesion	GO:0007155	329	0.021
glycosyl compound metabolic process	GO:1901657	246	0.021	Human Yeast
leukocyte differentiation	GO:0002521	342	0.021
purine nucleoside metabolic process	GO:0042278	241	0.020	Human Yeast
purine ribonucleotide metabolic process	GO:0009150	290	0.020	Human Yeast
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.020
endocrine system development	GO:0035270	98	0.020
regulation of granulocyte macrophage colony stimulating factor production	GO:0032645	3	0.020
regulation of cytoskeleton organization	GO:0051493	122	0.020
negative regulation of neuron death	GO:1901215	98	0.020
potassium ion homeostasis	GO:0055075	4	0.020
branching involved in salivary gland morphogenesis	GO:0060445	26	0.020
regulation of cell differentiation involved in embryonic placenta development	GO:0060800	1	0.020
detection of light stimulus	GO:0009583	25	0.020
cellular carbohydrate metabolic process	GO:0044262	119	0.020
positive regulation of cell migration	GO:0030335	109	0.020
detection of mechanical stimulus involved in sensory perception of pain	GO:0050966	4	0.020
anatomical structure homeostasis	GO:0060249	145	0.020
microtubule based process	GO:0007017	236	0.020
multi multicellular organism process	GO:0044706	109	0.019
multi organism behavior	GO:0051705	62	0.019
response to oxidative stress	GO:0006979	123	0.019
extrinsic apoptotic signaling pathway	GO:0097191	126	0.019
peptidyl tyrosine phosphorylation	GO:0018108	143	0.019	Mouse
mitotic cytokinesis	GO:0000281	4	0.019
circulatory system process	GO:0003013	197	0.019
hair cycle	GO:0042633	90	0.019
exocytosis	GO:0006887	121	0.019
cell proliferation in hindbrain	GO:0021534	10	0.019
carboxylic acid transport	GO:0046942	100	0.019
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.018
detection of stimulus involved in sensory perception	GO:0050906	44	0.018
regulation of synapse structural plasticity	GO:0051823	4	0.018
glycosyl compound catabolic process	GO:1901658	206	0.018	Human Yeast
regulation of cell growth	GO:0001558	91	0.018
small molecule biosynthetic process	GO:0044283	132	0.018
cerebellar cortex formation	GO:0021697	22	0.018
visual perception	GO:0007601	52	0.018
response to inactivity	GO:0014854	4	0.018
organelle fission	GO:0048285	170	0.018
negative regulation of phosphate metabolic process	GO:0045936	184	0.018
peptidyl serine phosphorylation	GO:0018105	74	0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.018
substantia nigra development	GO:0021762	2	0.018
skeletal system development	GO:0001501	356	0.018
extracellular matrix organization	GO:0030198	147	0.018
atrioventricular node cell fate commitment	GO:0060929	1	0.018
multicellular organismal homeostasis	GO:0048871	164	0.018
hexose metabolic process	GO:0019318	98	0.017
cellular metal ion homeostasis	GO:0006875	151	0.017
reactive oxygen species metabolic process	GO:0072593	84	0.017
cerebellum development	GO:0021549	77	0.017
regulation of blood pressure	GO:0008217	93	0.017
somatostatin receptor signaling pathway	GO:0038169	2	0.017
post embryonic retina morphogenesis in camera type eye	GO:0060060	3	0.017
apoptotic signaling pathway	GO:0097190	306	0.017
ameboidal type cell migration	GO:0001667	128	0.017
ribonucleoside catabolic process	GO:0042454	206	0.017	Human Yeast
organophosphate catabolic process	GO:0046434	232	0.017	Human Yeast
second messenger mediated signaling	GO:0019932	73	0.017
protein localization to plasma membrane	GO:0072659	57	0.017
lipid biosynthetic process	GO:0008610	179	0.017
glycerolipid metabolic process	GO:0046486	122	0.017
gastrin induced gastric acid secretion	GO:0001698	1	0.016
microtubule based movement	GO:0007018	84	0.016
microtubule polymerization or depolymerization	GO:0031109	26	0.016
regulation of neurological system process	GO:0031644	22	0.016
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.016
regulation of apoptotic signaling pathway	GO:2001233	197	0.016
regulation of monocyte extravasation	GO:2000437	2	0.016
positive regulation of cell activation	GO:0050867	158	0.016
negative regulation of wnt signaling pathway	GO:0030178	73	0.016
small molecule catabolic process	GO:0044282	71	0.016
cation homeostasis	GO:0055080	212	0.016
calcium ion homeostasis	GO:0055074	127	0.016
regulation of blood circulation	GO:1903522	93	0.016
wnt signaling pathway	GO:0016055	188	0.016
negative regulation of protein modification process	GO:0031400	163	0.016
nucleoside phosphate metabolic process	GO:0006753	338	0.016	Human Yeast
meiotic cell cycle	GO:0051321	122	0.016
horizontal cell localization	GO:0035852	1	0.016
cerebellar cortex development	GO:0021695	48	0.015
negative regulation of nervous system development	GO:0051961	156	0.015
positive regulation of protein kinase b signaling	GO:0051897	32	0.015
metanephric ascending thin limb development	GO:0072218	2	0.015
development of primary male sexual characteristics	GO:0046546	88	0.015
positive regulation of programmed cell death	GO:0043068	218	0.015
metanephric s shaped body morphogenesis	GO:0072284	2	0.015
response to light stimulus	GO:0009416	135	0.015
regulation of glutamate receptor signaling pathway	GO:1900449	16	0.015
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.015
regulation of body fluid levels	GO:0050878	162	0.015
peptidyl tyrosine modification	GO:0018212	145	0.015	Mouse
regulation of neurotransmitter transport	GO:0051588	35	0.015
single organismal cell cell adhesion	GO:0016337	131	0.015
cardiac muscle contraction	GO:0060048	32	0.015
nucleoside metabolic process	GO:0009116	246	0.015	Human Yeast
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.015	Human Yeast
lipid modification	GO:0030258	65	0.015
regulation of action potential	GO:0098900	4	0.015
ribonucleotide catabolic process	GO:0009261	208	0.015	Human Yeast
positive regulation of epithelial cell differentiation involved in kidney development	GO:2000698	2	0.015
camp mediated signaling	GO:0019933	15	0.015
potassium ion transmembrane transport	GO:0071805	43	0.014
catecholamine transport	GO:0051937	21	0.014
positive regulation of erk1 and erk2 cascade	GO:0070374	47	0.014
tissue homeostasis	GO:0001894	115	0.014
oocyte construction	GO:0007308	2	0.014
cellular protein complex assembly	GO:0043623	116	0.014
purine ribonucleoside metabolic process	GO:0046128	241	0.014	Human Yeast
purine ribonucleoside monophosphate metabolic process	GO:0009167	80	0.014
response to acid chemical	GO:0001101	111	0.014
intracellular mrna localization	GO:0008298	4	0.014
norepinephrine secretion	GO:0048243	2	0.014
positive regulation of cell growth	GO:0030307	33	0.014
negative regulation of organelle organization	GO:0010639	90	0.014
erk1 and erk2 cascade	GO:0070371	77	0.014
regulation of g protein coupled receptor protein signaling pathway	GO:0008277	37	0.014
cellularization	GO:0007349	1	0.014
positive regulation of gliogenesis	GO:0014015	27	0.014
mitotic cell cycle process	GO:1903047	159	0.014
positive regulation of inositol trisphosphate biosynthetic process	GO:0032962	2	0.014
positive regulation of dopamine secretion	GO:0033603	2	0.014
sensory perception of touch	GO:0050975	2	0.014
diencephalon development	GO:0021536	63	0.014
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.014
regulation of feeding behavior	GO:0060259	3	0.014
negative regulation of phosphorylation	GO:0042326	166	0.014
monoamine transport	GO:0015844	33	0.014
metanephric thick ascending limb development	GO:0072233	2	0.014
neuromuscular process controlling balance	GO:0050885	59	0.014
plasma membrane organization	GO:0007009	90	0.014
cerebral cortex development	GO:0021987	86	0.013
cytosolic calcium ion homeostasis	GO:0051480	70	0.013
monosaccharide transport	GO:0015749	58	0.013
gonad development	GO:0008406	141	0.013
histone modification	GO:0016570	159	0.013
ras protein signal transduction	GO:0007265	77	0.013	Mouse
organelle localization	GO:0051640	179	0.013
regulation of synaptic plasticity	GO:0048167	87	0.013
regulation of hormone levels	GO:0010817	211	0.013
regulation of lipid metabolic process	GO:0019216	118	0.013
immune effector process	GO:0002252	321	0.013
positive regulation of organelle organization	GO:0010638	128	0.013
regulation of microtubule polymerization or depolymerization	GO:0031110	20	0.013
cell migration involved in endocardial cushion formation	GO:0003273	3	0.013
negative regulation of phosphorus metabolic process	GO:0010563	184	0.013
ventricular compact myocardium morphogenesis	GO:0003223	2	0.013
activation of mapk activity	GO:0000187	59	0.013
cellular response to oxidative stress	GO:0034599	76	0.013
purine ribonucleoside catabolic process	GO:0046130	205	0.013	Human Yeast
regulation of fat cell differentiation	GO:0045598	81	0.013
cerebellar purkinje cell layer morphogenesis	GO:0021692	14	0.013
spermatogenesis	GO:0007283	284	0.013
regulation of lymphocyte activation	GO:0051249	240	0.013
amide transport	GO:0042886	138	0.013
sensory perception of pain	GO:0019233	47	0.013
purine nucleotide catabolic process	GO:0006195	211	0.013	Human Yeast
cerebellum morphogenesis	GO:0021587	42	0.013
guanosine containing compound metabolic process	GO:1901068	144	0.013	Human Yeast
negative regulation of cellular amine metabolic process	GO:0033239	1	0.013
organophosphate biosynthetic process	GO:0090407	122	0.013
organonitrogen compound biosynthetic process	GO:1901566	192	0.013
regulation of circadian sleep wake cycle rem sleep	GO:0042320	1	0.013
regulation of norepinephrine secretion	GO:0014061	2	0.013
positive regulation of transferase activity	GO:0051347	167	0.013
negative regulation of neuron differentiation	GO:0045665	101	0.013
intrinsic apoptotic signaling pathway in response to osmotic stress	GO:0008627	2	0.013
postganglionic parasympathetic nervous system development	GO:0021784	2	0.013
regulation of catecholamine secretion	GO:0050433	12	0.013
phospholipid metabolic process	GO:0006644	87	0.012
synaptic transmission involved in micturition	GO:0060084	3	0.012
microtubule based transport	GO:0010970	50	0.012
ribonucleoside metabolic process	GO:0009119	245	0.012	Human Yeast
pallium development	GO:0021543	120	0.012
digestive tract morphogenesis	GO:0048546	147	0.012
protein secretion	GO:0009306	111	0.012
muscle cell differentiation	GO:0042692	261	0.012
negative regulation of mapk cascade	GO:0043409	65	0.012
atp metabolic process	GO:0046034	75	0.012
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.012	Human Yeast
protein localization to organelle	GO:0033365	185	0.012
endocytosis	GO:0006897	168	0.012
peptidyl lysine modification	GO:0018205	77	0.012
pancreatic pp cell differentiation	GO:0003312	2	0.012
central nervous system morphogenesis	GO:0021551	2	0.012
visceral serous pericardium development	GO:0061032	2	0.012
regulation of lymphocyte differentiation	GO:0045619	107	0.012
ribose phosphate metabolic process	GO:0019693	291	0.012	Human Yeast
intrinsic apoptotic signaling pathway	GO:0097193	132	0.012
negative regulation of cell development	GO:0010721	169	0.012
negative regulation of cell adhesion involved in substrate bound cell migration	GO:0006933	3	0.012
skeletal muscle organ development	GO:0060538	163	0.012
regulation of anterior head development	GO:2000742	2	0.012
keratinocyte differentiation	GO:0030216	48	0.012
proprioception	GO:0019230	4	0.012
fast calcium ion dependent exocytosis of neurotransmitter	GO:0098746	1	0.012
regulation of smooth muscle contraction	GO:0006940	22	0.012
body fluid secretion	GO:0007589	53	0.012
respiratory system development	GO:0060541	190	0.012
axon cargo transport	GO:0008088	33	0.012
pancreatic a cell fate commitment	GO:0003326	2	0.012
immune response activating cell surface receptor signaling pathway	GO:0002429	72	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.012	Human Yeast
circadian sleep wake cycle rem sleep	GO:0042747	1	0.012
equilibrioception	GO:0050957	3	0.011
response to organic cyclic compound	GO:0014070	198	0.011
regulation of high voltage gated calcium channel activity	GO:1901841	2	0.011
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.011
regulation of epithelial cell proliferation	GO:0050678	141	0.011
monocarboxylic acid metabolic process	GO:0032787	191	0.011
cellular response to abiotic stimulus	GO:0071214	56	0.011
positive regulation of fat cell differentiation	GO:0045600	32	0.011
peripheral nervous system neuron axonogenesis	GO:0048936	3	0.011
nuclear transport	GO:0051169	139	0.011
stem cell maintenance	GO:0019827	130	0.011
oocyte axis specification	GO:0007309	2	0.011
positive regulation of extracellular matrix organization	GO:1903055	4	0.011
negative regulation of map kinase activity	GO:0043407	34	0.011
canonical wnt signaling pathway	GO:0060070	130	0.011
positive regulation of cell death	GO:0010942	224	0.011
regulation of protein kinase b signaling	GO:0051896	56	0.011
positive regulation of cellular component biogenesis	GO:0044089	94	0.011
immunoglobulin secretion involved in immune response	GO:0002380	2	0.011
positive regulation of apoptotic cell clearance	GO:2000427	3	0.011
cell maturation	GO:0048469	127	0.011
stem cell development	GO:0048864	219	0.011
positive regulation of interleukin 1 alpha production	GO:0032730	4	0.011
compound eye development	GO:0048749	1	0.011
striated muscle tissue development	GO:0014706	293	0.011
negative regulation of kinase activity	GO:0033673	81	0.011
regulation of protein complex disassembly	GO:0043244	28	0.011
protein targeting	GO:0006605	143	0.011
protein modification by small protein conjugation or removal	GO:0070647	207	0.011
regulation of carbohydrate biosynthetic process	GO:0043255	40	0.011
positive regulation of inositol phosphate biosynthetic process	GO:0060732	2	0.011
molting cycle	GO:0042303	90	0.011
regulation of cell cycle process	GO:0010564	160	0.011
vascular process in circulatory system	GO:0003018	62	0.011
water homeostasis	GO:0030104	27	0.011
amine transport	GO:0015837	21	0.011
negative regulation of protein complex disassembly	GO:0043242	22	0.011

Diras1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.034
nervous system disease	DOID:863	0.034
sensory system disease	DOID:0050155	0.013
retinal disease	DOID:5679	0.013
eye and adnexa disease	DOID:1492	0.013
eye disease	DOID:5614	0.013
retinal degeneration	DOID:8466	0.013

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