Mus musculus

29 known processes

Stx2

syntaxin 2

(Aliases: AW538950,MGC54718,Syn-2,Epim,repro34,G1-536-1)

Stx2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ras protein signal transductionGO:0007265770.498
small gtpase mediated signal transductionGO:0007264970.242
organic cyclic compound catabolic processGO:19013612950.221
regulation of cellular amino acid metabolic processGO:000652150.135
regulation of ras protein signal transductionGO:00465781140.120
peptidyl amino acid modificationGO:00181933360.115
cellular ketone metabolic processGO:0042180840.114
positive regulation of cellular amino acid metabolic processGO:004576430.112
purine ribonucleotide catabolic processGO:00091542080.110
purine ribonucleotide metabolic processGO:00091502900.110
rho protein signal transductionGO:0007266320.106
regulation of cellular amine metabolic processGO:0033238200.105
synaptic transmissionGO:00072683290.102
Mouse
amine metabolic processGO:0009308450.101
cellular amine metabolic processGO:0044106440.099
purine containing compound metabolic processGO:00725213110.094
nucleotide metabolic processGO:00091173320.094
nucleobase containing small molecule metabolic processGO:00550863520.092
heterocycle catabolic processGO:00467002800.083
purine nucleotide catabolic processGO:00061952110.080
aromatic compound catabolic processGO:00194392860.078
ribonucleoside triphosphate metabolic processGO:00091992200.077
macromolecule catabolic processGO:00090572810.076
membrane organizationGO:00610242450.072
Yeast Mouse
apoptotic signaling pathwayGO:00971903060.071
organophosphate catabolic processGO:00464342320.069
transmembrane transportGO:00550854120.069
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092071990.068
positive regulation of nucleotide metabolic processGO:00459811140.068
regulation of cellular ketone metabolic processGO:0010565660.066
regulation of nucleotide metabolic processGO:00061401690.066
regulation of nucleotide catabolic processGO:00308111220.066
purine nucleotide metabolic processGO:00061633020.066
nucleoside phosphate metabolic processGO:00067533380.065
ribonucleotide metabolic processGO:00092592910.064
cellular nitrogen compound catabolic processGO:00442702800.064
organonitrogen compound catabolic processGO:19015652640.063
purine ribonucleoside triphosphate metabolic processGO:00092052200.062
proteolysis involved in cellular protein catabolic processGO:00516031470.061
regulation of cell motilityGO:20001452360.061
regulation of intracellular transportGO:00323861590.061
muscle tissue developmentGO:00605373080.060
ribonucleotide catabolic processGO:00092612080.059
positive regulation of cellular amine metabolic processGO:003324050.058
purine nucleoside metabolic processGO:00422782410.058
intracellular protein transportGO:00068862040.058
nucleoside catabolic processGO:00091642060.057
cellular amino acid metabolic processGO:00065201030.057
nucleotide catabolic processGO:00091662170.056
positive regulation of cellular catabolic processGO:00313311480.054
ribonucleoside metabolic processGO:00091192450.054
regulation of apoptotic signaling pathwayGO:20012331970.053
purine nucleoside triphosphate catabolic processGO:00091462030.052
nucleoside triphosphate metabolic processGO:00091412300.049
purine containing compound catabolic processGO:00725232130.049
regulation of establishment of protein localizationGO:00702011810.049
regulation of purine nucleotide catabolic processGO:00331211220.049
nucleoside triphosphate catabolic processGO:00091432050.049
ubiquitin dependent protein catabolic processGO:00065111290.049
nucleoside phosphate catabolic processGO:19012922220.048
ribonucleoside triphosphate catabolic processGO:00092031990.048
glycosyl compound metabolic processGO:19016572460.048
nucleoside metabolic processGO:00091162460.047
regulation of organelle organizationGO:00330432890.047
purine nucleoside triphosphate metabolic processGO:00091442260.046
ribose phosphate metabolic processGO:00196932910.046
carbohydrate metabolic processGO:00059752300.046
sensory perceptionGO:00076002450.046
regulation of cellular catabolic processGO:00313292420.045
skeletal system developmentGO:00015013560.045
cell adhesionGO:00071553290.044
mapk cascadeGO:00001652810.043
positive regulation of purine nucleotide metabolic processGO:19005441140.043
positive regulation of programmed cell deathGO:00430682180.042
purine ribonucleoside metabolic processGO:00461282410.042
gtp catabolic processGO:00061841430.042
endocytosisGO:00068971680.042
purine nucleoside catabolic processGO:00061522050.041
protein modification by small protein conjugation or removalGO:00706472070.041
positive regulation of protein modification processGO:00314012990.041
organelle localizationGO:00516401790.040
Mouse
modification dependent protein catabolic processGO:00199411330.040
protein catabolic processGO:00301632210.039
multicellular organism growthGO:00352641610.039
cellular homeostasisGO:00197252400.039
regulation of hydrolase activityGO:00513362460.038
positive regulation of protein phosphorylationGO:00019342420.038
regulation of purine nucleotide metabolic processGO:19005421690.038
purine ribonucleoside catabolic processGO:00461302050.037
guanosine containing compound catabolic processGO:19010691440.037
protein localization to membraneGO:00726571080.037
cation transmembrane transportGO:00986552660.037
Mouse
cellular macromolecule catabolic processGO:00442652060.036
positive regulation of gtpase activityGO:0043547850.036
ribonucleoside catabolic processGO:00424542060.036
g protein coupled receptor signaling pathwayGO:00071862430.036
plasma membrane organizationGO:0007009900.035
modification dependent macromolecule catabolic processGO:00436321330.035
guanosine containing compound metabolic processGO:19010681440.035
response to organonitrogen compoundGO:00102432460.035
skin developmentGO:00435882200.035
glycosyl compound catabolic processGO:19016582060.034
endomembrane system organizationGO:00102561470.034
protein targetingGO:00066051430.033
regulation of secretion by cellGO:19035302490.033
Mouse
regulation of rho protein signal transductionGO:0035023710.033
peptidyl serine phosphorylationGO:0018105740.032
positive regulation of apoptotic processGO:00430652170.032
carbohydrate derivative catabolic processGO:19011362310.032
regulation of cell migrationGO:00303342190.032
regulation of vesicle mediated transportGO:00606271390.032
Mouse
negative regulation of cellular amino acid metabolic processGO:004576300.032
innate immune responseGO:00450871570.031
regulation of cell cycleGO:00517262810.031
negative regulation of molecular functionGO:00440922580.031
regulation of protein localizationGO:00328802310.030
peptidyl tyrosine phosphorylationGO:00181081430.030
immune response regulating signaling pathwayGO:00027641250.030
regulation of cytokine productionGO:00018172660.030
negative regulation of protein metabolic processGO:00512482820.030
regulation of cell projection organizationGO:00313442060.029
negative regulation of cell proliferationGO:00082852960.029
regulation of mapk cascadeGO:00434082480.029
cellular chemical homeostasisGO:00550822150.029
cell chemotaxisGO:0060326810.029
cell substrate adhesionGO:00315891300.029
regulation of gtp catabolic processGO:00331241130.029
negative regulation of cellular component organizationGO:00511291940.029
positive regulation of gtp catabolic processGO:0033126850.029
striated muscle tissue developmentGO:00147062930.028
epithelial cell proliferationGO:00506731740.028
regulation of transferase activityGO:00513382630.028
regulation of cellular response to stressGO:00801351590.028
asymmetric stem cell divisionGO:009872230.028
axonogenesisGO:00074092740.027
regulation of proteolysisGO:00301621640.027
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.027
skeletal muscle organ developmentGO:00605381630.027
establishment of protein localization to organelleGO:00725941180.027
immune effector processGO:00022523210.027
nuclear divisionGO:00002801580.027
gtp metabolic processGO:00460391440.026
interleukin 8 productionGO:003263740.026
response to acid chemicalGO:00011011110.026
positive regulation of cell motilityGO:20001471160.026
myeloid cell homeostasisGO:00022621140.026
cellular lipid metabolic processGO:00442553230.026
homeostasis of number of cellsGO:00488722100.026
epidermis developmentGO:00085441870.026
ion transmembrane transportGO:00342203610.026
Mouse
anion transportGO:00068201770.025
microtubule based processGO:00070172360.025
blood vessel morphogenesisGO:00485142850.025
developmental maturationGO:00217001930.025
intrinsic apoptotic signaling pathwayGO:00971931320.025
protein localization to organelleGO:00333651850.025
negative regulation of growthGO:0045926990.025
positive regulation of cell deathGO:00109422240.025
cellular ion homeostasisGO:00068731650.024
negative regulation of apoptotic signaling pathwayGO:20012341040.024
forebrain developmentGO:00309003020.024
dna metabolic processGO:00062593030.024
positive regulation of purine nucleotide catabolic processGO:0033123880.024
single organism cell adhesionGO:00986021560.024
lymphocyte proliferationGO:00466511640.024
protein ubiquitinationGO:00165671710.024
nitrogen compound transportGO:00717052710.024
skeletal system morphogenesisGO:00487052030.023
sensory organ morphogenesisGO:00905962420.023
regulation of muscle tissue developmentGO:1901861970.023
cellular component assembly involved in morphogenesisGO:00109271390.023
Yeast
positive regulation of secretionGO:00510471300.023
Mouse
response to peptideGO:19016521360.023
cellular protein catabolic processGO:00442571550.023
cytokine productionGO:00018163190.023
regulation of innate immune responseGO:0045088910.023
negative regulation of phosphorus metabolic processGO:00105631840.023
defense response to other organismGO:00985421970.023
cation transportGO:00068123990.023
Mouse
cilium morphogenesisGO:00602711020.023
regulation of defense responseGO:00313472330.023
leukocyte proliferationGO:00706611720.023
cellular response to organonitrogen compoundGO:00714171450.022
actin cytoskeleton organizationGO:00300362200.022
positive regulation of synaptic plasticityGO:003191540.022
negative regulation of immune system processGO:00026832090.022
negative regulation of protein modification processGO:00314001630.022
cation homeostasisGO:00550802120.021
regulation of hormone levelsGO:00108172110.021
gland developmentGO:00487323300.021
regulation of cell adhesionGO:00301551540.021
regulation of protein transportGO:00512231630.021
multicellular organismal homeostasisGO:00488711640.021
dephosphorylationGO:00163111290.021
calcium ion homeostasisGO:00550741270.021
appendage morphogenesisGO:00351071490.021
regulation of secretionGO:00510462740.021
Mouse
digestive tract morphogenesisGO:00485461470.021
negative regulation of cell migrationGO:0030336590.021
embryonic organ morphogenesisGO:00485622760.020
regulation of cell activationGO:00508652890.020
cell divisionGO:00513011200.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.020
maintenance of locationGO:0051235890.020
regulation of mitotic cell cycleGO:00073461260.020
cellular protein complex assemblyGO:00436231160.020
Mouse
anatomical structure homeostasisGO:00602491450.020
asymmetric neuroblast divisionGO:005505910.020
peptidyl tyrosine modificationGO:00182121450.020
cellular divalent inorganic cation homeostasisGO:00725031270.019
microtubule cytoskeleton organizationGO:00002261570.019
regulation of protein kinase activityGO:00458592320.019
negative regulation of cellular amine metabolic processGO:003323910.019
locomotory behaviorGO:00076261950.019
organonitrogen compound biosynthetic processGO:19015661920.019
establishment of vesicle localizationGO:0051650810.019
Mouse
organic hydroxy compound metabolic processGO:19016152030.019
positive regulation of mapk cascadeGO:00434101700.019
sequestering of calcium ionGO:0051208180.019
positive regulation of transferase activityGO:00513471670.019
immune response activating cell surface receptor signaling pathwayGO:0002429720.019
protein autophosphorylationGO:0046777610.019
organelle assemblyGO:00709251770.019
spermatogenesisGO:00072832840.019
divalent inorganic cation homeostasisGO:00725071380.019
divalent inorganic cation transportGO:00725111780.018
Mouse
chemotaxisGO:00069352470.018
proteasomal protein catabolic processGO:0010498980.018
posttranscriptional regulation of gene expressionGO:00106081550.018
regulation of cell morphogenesis involved in differentiationGO:00107691510.018
gastrulationGO:00073691160.018
regulation of hormone secretionGO:0046883880.018
regulation of cytoskeleton organizationGO:00514931220.018
meiotic cell cycleGO:00513211220.018
Yeast
positive regulation of nucleotide catabolic processGO:0030813880.018
regulation of interleukin 8 productionGO:003267730.018
histone modificationGO:00165701590.018
peptide secretionGO:00027901140.018
engulfment of apoptotic cellGO:004365230.018
regulation of anatomical structure sizeGO:00900661780.018
response to peptide hormoneGO:00434341270.018
response to oxidative stressGO:00069791230.018
divalent metal ion transportGO:00708381720.018
Mouse
fertilizationGO:00095661270.017
cell type specific apoptotic processGO:00972852680.017
cellular response to cytokine stimulusGO:00713451890.017
tissue homeostasisGO:00018941150.017
single fertilizationGO:0007338820.017
positive regulation of nucleoside metabolic processGO:0045979910.017
positive regulation of organelle organizationGO:00106381280.017
signal transduction in absence of ligandGO:0038034550.017
extrinsic apoptotic signaling pathwayGO:00971911260.017
inorganic cation transmembrane transportGO:00986622070.017
Mouse
calcium ion transportGO:00068161590.017
Mouse
peptidyl serine modificationGO:0018209830.017
regulation of transmembrane transportGO:00347621280.017
male gamete generationGO:00482322850.017
cell growthGO:00160491300.017
establishment of protein localization to membraneGO:0090150540.017
regulation of membrane potentialGO:00423911920.017
Mouse
telencephalon developmentGO:00215371860.017
mitotic cell cycleGO:00002781950.017
muscle cell differentiationGO:00426922610.016
negative regulation of intracellular signal transductionGO:19025321670.016
regulation of cell cycle processGO:00105641600.016
carbohydrate homeostasisGO:00335001280.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
digestive system developmentGO:00551232000.016
glycerolipid metabolic processGO:00464861220.016
regulation of actin filament based processGO:0032970990.016
cellular metal ion homeostasisGO:00068751510.016
peptide hormone secretionGO:00300721090.016
epithelial cell developmentGO:00020641590.016
organophosphate biosynthetic processGO:00904071220.016
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.016
regulation of epithelial cell proliferationGO:00506781410.016
negative regulation of organelle organizationGO:0010639900.016
oxidation reduction processGO:00551143420.016
chromatin modificationGO:00165681870.016
negative regulation of cellular protein metabolic processGO:00322692470.015
protein localization to nucleusGO:00345041210.015
positive regulation of ras gtpase activityGO:0032320650.015
regulation of neuron differentiationGO:00456642810.015
limb morphogenesisGO:00351081490.015
appendage developmentGO:00487361660.015
glycerophospholipid metabolic processGO:0006650710.015
hexose metabolic processGO:0019318980.015
organelle fissionGO:00482851700.015
regulation of ras gtpase activityGO:0032318880.015
regulation of endocytosisGO:0030100690.015
action potentialGO:0001508780.015
organic acid transportGO:00158491010.015
negative regulation of nervous system developmentGO:00519611560.015
cellular carbohydrate metabolic processGO:00442621190.015
immune response activating signal transductionGO:00027571160.015
angiogenesisGO:00015252010.015
germ cell developmentGO:00072811850.015
striated muscle cell developmentGO:00550021250.015
cytokinetic processGO:003250620.015
response to inorganic substanceGO:0010035960.014
positive regulation of nervous system developmentGO:00519622210.014
mitochondrion distributionGO:004831140.014
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.014
glucose homeostasisGO:00425931280.014
learning or memoryGO:00076111480.014
ear developmentGO:00435832000.014
antigen receptor mediated signaling pathwayGO:0050851640.014
limb developmentGO:00601731660.014
metencephalon developmentGO:0022037890.014
dendrite developmentGO:00163581150.014
leukocyte mediated immunityGO:00024431740.014
protein importGO:00170381010.014
response to molecule of bacterial originGO:00022371430.014
sulfur compound metabolic processGO:00067901000.014
camera type eye developmentGO:00430102660.014
activation of immune responseGO:00022531380.014
single organismal cell cell adhesionGO:00163371310.014
compound eye developmentGO:004874910.014
regulation of ion transportGO:00432692150.014
positive regulation of hydrolase activityGO:00513451480.014
carbohydrate derivative biosynthetic processGO:19011371830.014
neuron projection extensionGO:1990138640.014
negative regulation of cell cycleGO:00457861230.014
substrate adhesion dependent cell spreadingGO:0034446300.014
multicellular organismal signalingGO:0035637910.013
regulation of kinase activityGO:00435492490.013
myeloid cell differentiationGO:00300992330.013
epithelial tube morphogenesisGO:00605623030.013
positive regulation of secretion by cellGO:19035321140.013
Mouse
detection of stimulusGO:0051606840.013
protein modification by small protein conjugationGO:00324461870.013
negative regulation of cell developmentGO:00107211690.013
pallium developmentGO:00215431200.013
developmental growth involved in morphogenesisGO:00605601380.013
cellular response to carbohydrate stimulusGO:0071322500.013
peptide transportGO:00158331330.013
regulation of lymphocyte activationGO:00512492400.013
hormone secretionGO:00468791280.013
epithelial tube formationGO:00721751300.013
cell maturationGO:00484691270.013
cognitionGO:00508901490.013
digestive tract developmentGO:00485651900.013
regulation of metal ion transportGO:00109591060.013
cellular response to peptideGO:1901653920.013
regulation of ion transmembrane transportGO:00347651190.013
regulation of ral gtpase activityGO:003231540.013
regulation of chromatin modificationGO:1903308570.012
cellular response to growth factor stimulusGO:00713631970.012
lamellipodium organizationGO:0097581290.012
regulation of intracellular protein transportGO:0033157820.012
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.012
retrograde transport endosome to golgiGO:004214720.012
plasma lipoprotein particle clearanceGO:0034381130.012
negative regulation of phosphorylationGO:00423261660.012
nucleocytoplasmic transportGO:00069131390.012
photoreceptor cell developmentGO:0042461400.012
response to lipopolysaccharideGO:00324961280.012
leukocyte differentiationGO:00025213420.012
carboxylic acid transportGO:00469421000.012
cellular calcium ion homeostasisGO:00068741190.012
embryonic limb morphogenesisGO:00303261260.012
response to amino acidGO:0043200370.012
regulation of protein serine threonine kinase activityGO:00719001570.012
lipid localizationGO:00108761260.012
regulation of homeostatic processGO:00328441820.012
vesicle organizationGO:0016050600.012
Yeast Mouse
glycoprotein metabolic processGO:00091001160.012
regulation of synaptic plasticityGO:0048167870.012
lung developmentGO:00303241640.012
inorganic ion transmembrane transportGO:00986602340.012
Mouse
positive regulation of protein kinase activityGO:00458601440.012
actin filament organizationGO:00070151130.012
regulation of striated muscle cell differentiationGO:0051153810.012
negative regulation of cell motilityGO:2000146610.012
myeloid leukocyte migrationGO:0097529570.012
regulation of chemotaxisGO:0050920530.012
response to radiationGO:00093141650.012
negative regulation of intracellular transportGO:0032387380.012
cytoplasmic transportGO:00164822340.012
regulation of cytoplasmic transportGO:19036491120.012
fat soluble vitamin biosynthetic processGO:004236240.012
regulation of chromosome organizationGO:0033044830.012
activation of adenylate cyclase activityGO:000719040.012
regulation of peptidyl tyrosine phosphorylationGO:0050730930.012
carbohydrate biosynthetic processGO:0016051740.012
positive regulation of immune effector processGO:00026991070.011
stress activated protein kinase signaling cascadeGO:0031098810.011
cellular response to abiotic stimulusGO:0071214560.011
regulation of ral protein signal transductionGO:003248540.011
cellular response to dna damage stimulusGO:00069742070.011
sequestering of metal ionGO:0051238190.011
palate developmentGO:0060021760.011
positive regulation of interleukin 8 productionGO:003275720.011
organic anion transportGO:00157111370.011
protein import into nucleusGO:0006606950.011
protein localization to plasma membraneGO:0072659570.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
cellular response to peptide hormone stimulusGO:0071375920.011
meiotic cell cycle processGO:1903046770.011
Yeast
regulation of protein targetingGO:1903533610.011
retina development in camera type eyeGO:00600411190.011
learningGO:0007612980.011
interspecies interaction between organismsGO:0044419830.011
cilium assemblyGO:0042384810.011
neuron migrationGO:00017641220.011
fat cell differentiationGO:00454441600.011
blood coagulationGO:0007596760.011
Human
mitotic cell cycle processGO:19030471590.011
nucleotide biosynthetic processGO:0009165780.011
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.011
myeloid leukocyte differentiationGO:00025731190.011
synaptic vesicle localizationGO:0097479590.011
Mouse
response to organic cyclic compoundGO:00140701980.011
single organism nuclear importGO:1902593950.011
positive regulation of protein catabolic processGO:0045732600.011
actin filament polymerizationGO:0030041440.011
photoreceptor cell differentiationGO:0046530520.011
insulin secretionGO:0030073890.011
localization within membraneGO:005166840.011
intracellular distribution of mitochondriaGO:004831210.011
cellular response to acid chemicalGO:0071229680.011
neural tube developmentGO:00219151600.011
blood circulationGO:00080151950.011
regulation of body fluid levelsGO:00508781620.011
Human
heart contractionGO:0060047930.011
spermatid differentiationGO:00485151150.011
regulation of myotube differentiationGO:0010830620.011
sensory perception of mechanical stimulusGO:00509541070.011
extracellular matrix organizationGO:00301981470.010
positive regulation of cell developmentGO:00107202370.010
body morphogenesisGO:0010171450.010
positive regulation of protein serine threonine kinase activityGO:00719021060.010
cytokine mediated signaling pathwayGO:00192211150.010
actin filament severingGO:005101410.010
cofactor metabolic processGO:0051186800.010
transmission of nerve impulseGO:0019226760.010
actomyosin structure organizationGO:0031032560.010
central nervous system neuron differentiationGO:00219531620.010
sensory perception of soundGO:0007605970.010
regulation of androgen receptor signaling pathwayGO:006076530.010
positive regulation of kinase activityGO:00336741550.010
regulation of cellular component biogenesisGO:00440871810.010
Mouse
neuromuscular processGO:0050905990.010
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.010
norepinephrine transportGO:001587420.010
metal ion homeostasisGO:00550651890.010
glycolipid metabolic processGO:0006664250.010
negative regulation of phosphate metabolic processGO:00459361840.010
negative regulation of transferase activityGO:0051348850.010
monocarboxylic acid metabolic processGO:00327871910.010
alcohol metabolic processGO:00060661160.010
lipid biosynthetic processGO:00086101790.010
intestinal epithelial structure maintenanceGO:006072940.010
tissue migrationGO:0090130680.010

Stx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:6500.060
musculoskeletal system diseaseDOID:1700.060
disease of anatomical entityDOID:700.060
nervous system diseaseDOID:86300.013
central nervous system diseaseDOID:33100.013