Mus musculus

29 known processes

Txnrd1

thioredoxin reductase 1

(Aliases: TR1,TrxR1,TR)

Txnrd1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.175
Rat
mitochondrion organizationGO:00070051340.107
oxidation reduction processGO:00551143420.092
response to oxidative stressGO:00069791230.089
Rat
spermatogenesisGO:00072832840.079
cellular amine metabolic processGO:0044106440.057
amine metabolic processGO:0009308450.057
glutathione metabolic processGO:0006749160.057
Rat
regulation of cellular ketone metabolic processGO:0010565660.055
response to organonitrogen compoundGO:00102432460.055
protein modification by small protein conjugation or removalGO:00706472070.050
dna metabolic processGO:00062593030.048
cellular response to dna damage stimulusGO:00069742070.046
protein localization to organelleGO:00333651850.046
positive regulation of cellular amino acid metabolic processGO:004576430.045
regulation of protein localizationGO:00328802310.044
protein ubiquitinationGO:00165671710.044
cytoplasmic transportGO:00164822340.044
response to inorganic substanceGO:0010035960.044
Rat
posttranscriptional regulation of gene expressionGO:00106081550.043
male gamete generationGO:00482322850.043
protein modification by small protein conjugationGO:00324461870.043
apoptotic signaling pathwayGO:00971903060.043
maintenance of locationGO:0051235890.042
aromatic compound catabolic processGO:00194392860.042
regulation of apoptotic signaling pathwayGO:20012331970.042
organic cyclic compound catabolic processGO:19013612950.041
intrinsic apoptotic signaling pathwayGO:00971931320.041
positive regulation of cellular amine metabolic processGO:003324050.040
transmembrane transportGO:00550854120.040
small molecule biosynthetic processGO:00442831320.039
regulation of cellular amino acid metabolic processGO:000652150.038
neural tube formationGO:00018411080.037
cation homeostasisGO:00550802120.037
regulation of organelle organizationGO:00330432890.037
cellular protein complex assemblyGO:00436231160.036
cellular response to lipidGO:00713961450.036
sensory perceptionGO:00076002450.036
response to oxygen radicalGO:0000305160.036
cellular ketone metabolic processGO:0042180840.036
peptide metabolic processGO:0006518460.035
Rat
ras protein signal transductionGO:0007265770.035
response to organic cyclic compoundGO:00140701980.035
translationGO:0006412930.035
response to acid chemicalGO:00011011110.034
translational initiationGO:0006413240.034
negative regulation of cellular amino acid metabolic processGO:004576300.033
microtubule based processGO:00070172360.033
protein alkylationGO:0008213810.033
purine nucleotide catabolic processGO:00061952110.032
methylationGO:00322591340.032
purine containing compound metabolic processGO:00725213110.032
establishment of protein localization to organelleGO:00725941180.031
cellular homeostasisGO:00197252400.031
heterocycle catabolic processGO:00467002800.031
regulation of cellular amine metabolic processGO:0033238200.030
nucleobase containing small molecule metabolic processGO:00550863520.030
Rat
inflammatory responseGO:00069542440.030
response to radiationGO:00093141650.030
organelle fissionGO:00482851700.029
myeloid cell differentiationGO:00300992330.029
embryonic organ morphogenesisGO:00485622760.028
organonitrogen compound catabolic processGO:19015652640.028
cellular amide metabolic processGO:0043603580.028
Rat
muscle tissue developmentGO:00605373080.028
regulation of cellular catabolic processGO:00313292420.028
protein targetingGO:00066051430.028
response to reactive oxygen speciesGO:0000302560.028
Rat
regulation of protein transportGO:00512231630.027
epithelial tube morphogenesisGO:00605623030.027
regulation of membrane potentialGO:00423911920.027
locomotory behaviorGO:00076261950.026
positive regulation of cellular catabolic processGO:00313311480.026
regulation of transferase activityGO:00513382630.026
nitrogen compound transportGO:00717052710.026
protein methylationGO:0006479810.026
peptidyl amino acid modificationGO:00181933360.026
ion transmembrane transportGO:00342203610.026
cellular lipid metabolic processGO:00442553230.026
positive regulation of cell deathGO:00109422240.026
Rat
cellular macromolecule catabolic processGO:00442652060.026
mapk cascadeGO:00001652810.025
positive regulation of protein modification processGO:00314012990.025
cellular response to molecule of bacterial originGO:0071219830.025
sensory organ morphogenesisGO:00905962420.025
neural tube developmentGO:00219151600.025
cation transportGO:00068123990.025
regulation of cytoskeleton organizationGO:00514931220.024
nucleoside metabolic processGO:00091162460.024
peptidyl tyrosine phosphorylationGO:00181081430.024
response to superoxideGO:0000303160.024
establishment or maintenance of cytoskeleton polarityGO:003095220.024
nucleoside phosphate metabolic processGO:00067533380.024
Rat
negative regulation of cellular component organizationGO:00511291940.024
t cell activationGO:00421102890.024
regionalizationGO:00030023370.023
regulation of lymphocyte activationGO:00512492400.023
organelle disassemblyGO:190300820.023
monocarboxylic acid metabolic processGO:00327871910.023
ossificationGO:00015032160.023
nuclear divisionGO:00002801580.023
oocyte axis specificationGO:000730920.022
regulation of anatomical structure sizeGO:00900661780.022
oocyte anterior posterior axis specificationGO:000731420.022
regulation of intracellular transportGO:00323861590.022
regulation of proteolysisGO:00301621640.022
carboxylic acid biosynthetic processGO:0046394860.022
blood vessel morphogenesisGO:00485142850.022
organic acid biosynthetic processGO:0016053860.022
regulation of defense responseGO:00313472330.022
angiogenesisGO:00015252010.022
cellular response to organonitrogen compoundGO:00714171450.021
regulation of cell activationGO:00508652890.021
mitotic cell cycleGO:00002781950.021
protein importGO:00170381010.021
myeloid leukocyte differentiationGO:00025731190.021
lipid localizationGO:00108761260.021
organophosphate catabolic processGO:00464342320.021
reactive oxygen species metabolic processGO:0072593840.021
Rat
morphogenesis of embryonic epitheliumGO:00163311590.021
cellular nitrogen compound catabolic processGO:00442702800.021
leukocyte differentiationGO:00025213420.021
cellular ion homeostasisGO:00068731650.021
actin cytoskeleton organizationGO:00300362200.021
regulation of secretion by cellGO:19035302490.021
microtubule cytoskeleton organizationGO:00002261570.021
regulation of kinase activityGO:00435492490.021
forebrain developmentGO:00309003020.021
embryonic epithelial tube formationGO:00018381300.021
nucleoside triphosphate metabolic processGO:00091412300.020
ribonucleoside metabolic processGO:00091192450.020
skeletal system developmentGO:00015013560.020
proteolysis involved in cellular protein catabolic processGO:00516031470.020
regulation of mapk cascadeGO:00434082480.020
negative regulation of protein metabolic processGO:00512482820.020
cellular response to biotic stimulusGO:0071216920.020
regulation of hydrolase activityGO:00513362460.020
cellular chemical homeostasisGO:00550822150.020
negative regulation of apoptotic signaling pathwayGO:20012341040.020
single organism cell adhesionGO:00986021560.020
tube formationGO:00351481400.020
urogenital system developmentGO:00016552610.020
response to lipopolysaccharideGO:00324961280.019
response to extracellular stimulusGO:00099911270.019
circulatory system processGO:00030131970.019
membrane organizationGO:00610242450.019
oocyte constructionGO:000730820.019
regulation of secretionGO:00510462740.019
peptidyl tyrosine modificationGO:00182121450.019
negative regulation of intracellular signal transductionGO:19025321670.019
positive regulation of cell developmentGO:00107202370.019
cellular metal ion homeostasisGO:00068751510.019
cellular protein complex disassemblyGO:0043624360.019
cellular response to lipopolysaccharideGO:0071222770.019
positive regulation of programmed cell deathGO:00430682180.018
stem cell developmentGO:00488642190.018
cellularizationGO:000734910.018
response to endoplasmic reticulum stressGO:0034976530.018
purine ribonucleoside metabolic processGO:00461282410.018
protein localization to nucleusGO:00345041210.018
organic anion transportGO:00157111370.018
response to molecule of bacterial originGO:00022371430.018
purine nucleotide metabolic processGO:00061633020.018
organic hydroxy compound metabolic processGO:19016152030.018
muscle cell differentiationGO:00426922610.018
innate immune responseGO:00450871570.018
negative regulation of cellular amine metabolic processGO:003323910.018
cytokine productionGO:00018163190.018
epithelial cell developmentGO:00020641590.018
regulation of hormone levelsGO:00108172110.018
negative regulation of molecular functionGO:00440922580.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
immune effector processGO:00022523210.018
regulation of nucleotide metabolic processGO:00061401690.018
regulation of neuron differentiationGO:00456642810.018
small gtpase mediated signal transductionGO:0007264970.018
renal system developmentGO:00720012250.018
macromolecule catabolic processGO:00090572810.018
skeletal system morphogenesisGO:00487052030.018
purine ribonucleotide metabolic processGO:00091502900.018
metal ion homeostasisGO:00550651890.017
organonitrogen compound biosynthetic processGO:19015661920.017
intracellular protein transportGO:00068862040.017
negative regulation of cellular protein metabolic processGO:00322692470.017
regulation of purine nucleotide metabolic processGO:19005421690.017
positive regulation of kinase activityGO:00336741550.017
camera type eye developmentGO:00430102660.017
nucleoside phosphate catabolic processGO:19012922220.017
response to alkaloidGO:0043279340.017
glycosyl compound catabolic processGO:19016582060.017
wound healingGO:00420601570.017
homeostasis of number of cellsGO:00488722100.017
rhythmic processGO:00485111740.017
cellular response to hormone stimulusGO:00328701500.017
gland developmentGO:00487323300.017
female gamete generationGO:0007292740.017
germ cell developmentGO:00072811850.017
multi multicellular organism processGO:00447061090.017
regulation of cell cycle processGO:00105641600.017
regulation of cellular component biogenesisGO:00440871810.017
protein import into nucleusGO:0006606950.017
positive regulation of peptidase activityGO:0010952490.016
lipid biosynthetic processGO:00086101790.016
compound eye developmentGO:004874910.016
regulation of cytokine productionGO:00018172660.016
regulation of leukocyte differentiationGO:19021051590.016
carbohydrate derivative biosynthetic processGO:19011371830.016
negative regulation of phosphate metabolic processGO:00459361840.016
positive regulation of protein transportGO:0051222930.016
single organism nuclear importGO:1902593950.016
negative regulation of phosphorus metabolic processGO:00105631840.016
nucleocytoplasmic transportGO:00069131390.016
blood circulationGO:00080151950.016
regulation of establishment of protein localizationGO:00702011810.016
endocytosisGO:00068971680.016
generation of precursor metabolites and energyGO:00060911030.016
engulfment of apoptotic cellGO:004365230.016
cellular carbohydrate metabolic processGO:00442621190.016
negative regulation of protein modification processGO:00314001630.016
ribonucleoside catabolic processGO:00424542060.016
negative regulation of cell proliferationGO:00082852960.016
maternal determination of anterior posterior axis embryoGO:000835820.016
positive regulation of apoptotic processGO:00430652170.016
organophosphate biosynthetic processGO:00904071220.016
organism emergence from protective structureGO:007168440.016
inorganic ion transmembrane transportGO:00986602340.016
regulation of inflammatory responseGO:00507271470.016
actin filament organizationGO:00070151130.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
positive regulation of hydrolase activityGO:00513451480.015
glucose homeostasisGO:00425931280.015
anatomical structure homeostasisGO:00602491450.015
regulation of cell adhesionGO:00301551540.015
cellular response to acid chemicalGO:0071229680.015
response to oxygen levelsGO:0070482620.015
Rat
ribonucleotide metabolic processGO:00092592910.015
regulation of homeostatic processGO:00328441820.015
leukocyte proliferationGO:00706611720.015
carbohydrate metabolic processGO:00059752300.015
stem cell differentiationGO:00488632680.015
inorganic cation transmembrane transportGO:00986622070.015
positive regulation of protein phosphorylationGO:00019342420.015
ribose phosphate metabolic processGO:00196932910.015
neural tube closureGO:0001843900.015
response to light stimulusGO:00094161350.015
epidermis developmentGO:00085441870.015
kidney developmentGO:00018222130.015
regulation of reactive oxygen species metabolic processGO:2000377400.015
ribonucleoprotein complex disassemblyGO:003298830.015
regulation of cell cycleGO:00517262810.014
cellular response to cytokine stimulusGO:00713451890.014
respiratory system developmentGO:00605411900.014
protein secretionGO:00093061110.014
pole plasm assemblyGO:000731520.014
regulation of synaptic growth at neuromuscular junctionGO:000858240.014
cell type specific apoptotic processGO:00972852680.014
regulation of protein catabolic processGO:00421761080.014
response to nutrient levelsGO:00316671090.014
extracellular matrix organizationGO:00301981470.014
regulation of cell divisionGO:0051302760.014
muscle system processGO:00030121410.014
striated muscle tissue developmentGO:00147062930.014
extrinsic apoptotic signaling pathwayGO:00971911260.014
regulation of ion transportGO:00432692150.014
purine ribonucleoside catabolic processGO:00461302050.014
multicellular organismal homeostasisGO:00488711640.014
regulation of cell migrationGO:00303342190.014
energy derivation by oxidation of organic compoundsGO:0015980770.014
mitotic cell cycle processGO:19030471590.014
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.014
positive regulation of nervous system developmentGO:00519622210.014
positive regulation of lymphocyte activationGO:00512511400.014
regulation of protein serine threonine kinase activityGO:00719001570.014
protein maturationGO:00516041760.014
nucleoside monophosphate metabolic processGO:0009123850.014
response to amino acidGO:0043200370.014
lymphocyte proliferationGO:00466511640.014
response to vitamin aGO:003318910.013
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.013
hormone secretionGO:00468791280.013
cell adhesionGO:00071553290.013
meiotic cell cycleGO:00513211220.013
regulation of system processGO:00440572000.013
negative regulation of synapse assemblyGO:005196430.013
g protein coupled receptor signaling pathwayGO:00071862430.013
macromolecule methylationGO:00434141200.013
purine nucleoside metabolic processGO:00422782410.013
molting cycleGO:0042303900.013
lateral inhibitionGO:004633110.013
regulation of protein complex assemblyGO:0043254830.013
organic hydroxy compound transportGO:0015850930.013
monosaccharide metabolic processGO:00059961060.013
transmission of nerve impulseGO:0019226760.013
positive regulation of immune effector processGO:00026991070.013
nuclear transportGO:00511691390.013
b cell activationGO:00421131610.013
cellular divalent inorganic cation homeostasisGO:00725031270.013
mitochondrion degradationGO:000042230.013
positive regulation of organelle organizationGO:00106381280.013
connective tissue developmentGO:00614481790.013
leukocyte mediated immunityGO:00024431740.013
amide transportGO:00428861380.013
regulation of endopeptidase activityGO:0052548890.013
organic hydroxy compound biosynthetic processGO:1901617770.013
positive regulation of proteolysisGO:0045862850.013
nuclear importGO:0051170950.013
glycosyl compound metabolic processGO:19016572460.013
divalent inorganic cation homeostasisGO:00725071380.013
dna endoreduplicationGO:004202340.013
regulation of response to woundingGO:19030341890.013
action potentialGO:0001508780.013
cognitionGO:00508901490.013
positive regulation of nucleotide metabolic processGO:00459811140.012
peptide transportGO:00158331330.012
organelle localizationGO:00516401790.012
purine nucleoside triphosphate catabolic processGO:00091462030.012
regulation of protein localization to nucleusGO:1900180600.012
morphogenesis of a branching structureGO:00017632030.012
developmental maturationGO:00217001930.012
regulation of asymmetric cell divisionGO:000978640.012
cellular response to oxidative stressGO:0034599760.012
Rat
cajal body organizationGO:003057610.012
regulation of protein targetingGO:1903533610.012
dephosphorylationGO:00163111290.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
epithelial tube formationGO:00721751300.012
ear developmentGO:00435832000.012
proteasomal protein catabolic processGO:0010498980.012
regulation of body fluid levelsGO:00508781620.012
cation transmembrane transportGO:00986552660.012
regulation of ras protein signal transductionGO:00465781140.012
divalent inorganic cation transportGO:00725111780.012
synaptic transmissionGO:00072683290.012
regulation of chromosome organizationGO:0033044830.012
adult behaviorGO:00305341350.012
multicellular organismal signalingGO:0035637910.012
cellular response to organic cyclic compoundGO:0071407870.012
chromatin modificationGO:00165681870.012
carbohydrate homeostasisGO:00335001280.012
autophagyGO:0006914450.012
negative regulation of protein phosphorylationGO:00019331260.012
i kappab kinase nf kappab signalingGO:0007249850.012
digestive system developmentGO:00551232000.012
regulation of cell projection organizationGO:00313442060.012
rho protein signal transductionGO:0007266320.012
regulation of t cell activationGO:00508631700.012
morphogenesis of a branching epitheliumGO:00611381930.012
dna repairGO:00062811070.012
regulation of cell motilityGO:20001452360.012
fatty acid metabolic processGO:00066311210.011
regulation of tube sizeGO:0035150570.011
inter male aggressive behaviorGO:000212130.011
divalent metal ion transportGO:00708381720.011
heart morphogenesisGO:00030071780.011
nucleoside triphosphate catabolic processGO:00091432050.011
learning or memoryGO:00076111480.011
regulation of transmembrane transportGO:00347621280.011
macromolecular complex disassemblyGO:0032984430.011
hexose metabolic processGO:0019318980.011
regulation of cytoplasmic transportGO:19036491120.011
cellular response to amino acid stimulusGO:0071230290.011
striated muscle cell developmentGO:00550021250.011
calcium ion homeostasisGO:00550741270.011
alpha amino acid metabolic processGO:1901605590.011
Rat
nucleus organizationGO:0006997450.011
dna recombinationGO:0006310920.011
chromatin organizationGO:00063252060.011
regulation of lamellipodium assemblyGO:001059130.011
regulation of peptidase activityGO:0052547960.011
ribonucleotide catabolic processGO:00092612080.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.011
muscle cell developmentGO:00550011330.011
anion transmembrane transportGO:0098656710.011
cellular response to external stimulusGO:0071496880.011
striated muscle myosin thick filament assemblyGO:007168810.011
positive regulation of endopeptidase activityGO:0010950430.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.011
myosin filament assemblyGO:003103420.011
muscle contractionGO:00069361010.011
t cell differentiationGO:00302171740.011
cellular response to carbohydrate stimulusGO:0071322500.011
purine containing compound catabolic processGO:00725232130.011
retina development in camera type eyeGO:00600411190.011
carbohydrate derivative catabolic processGO:19011362310.011
positive regulation of cell activationGO:00508671580.011
fertilizationGO:00095661270.011
negative regulation of transferase activityGO:0051348850.011
ribonucleoside triphosphate catabolic processGO:00092031990.011
regulation of purine nucleotide catabolic processGO:00331211220.011
protein processingGO:00164851630.011
regulation of myeloid leukocyte differentiationGO:0002761580.011
double strand break repairGO:0006302480.011
primary neural tube formationGO:0014020950.011
skin developmentGO:00435882200.011
interleukin 8 productionGO:003263740.011
hatchingGO:003518840.011
regulation of organ morphogenesisGO:20000271440.011
extracellular structure organizationGO:00430621480.011
mesoderm developmentGO:00074981000.011
cofactor metabolic processGO:0051186800.011
Rat
nucleoside phosphate biosynthetic processGO:1901293790.010
positive regulation of reactive oxygen species metabolic processGO:2000379110.010
cellular response to gamma radiationGO:007148040.010
cellular calcium ion homeostasisGO:00068741190.010
t cell proliferationGO:00420981200.010
negative regulation of nervous system developmentGO:00519611560.010
multicellular organism growthGO:00352641610.010
regulation of protein kinase activityGO:00458592320.010
endomembrane system organizationGO:00102561470.010
ear morphogenesisGO:00424711180.010
regulation of cysteine type endopeptidase activityGO:2000116650.010
regulation of nucleoside metabolic processGO:00091181300.010
adaptive immune responseGO:00022501550.010
positive regulation of transferase activityGO:00513471670.010
lipid transportGO:0006869980.010
cellular modified amino acid metabolic processGO:0006575630.010
Rat
regulation of lymphocyte proliferationGO:00506701170.010
negative regulation of organelle organizationGO:0010639900.010
purine ribonucleoside triphosphate catabolic processGO:00092071990.010
neuron deathGO:00709971540.010
cytokine mediated signaling pathwayGO:00192211150.010
skeletal muscle organ developmentGO:00605381630.010

Txnrd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.088
disease of anatomical entityDOID:700.088
central nervous system diseaseDOID:33100.032
disease of cellular proliferationDOID:1456600.017
organ system cancerDOID:005068600.017
cancerDOID:16200.017
sensory system diseaseDOID:005015500.015
eye and adnexa diseaseDOID:149200.012
eye diseaseDOID:561400.012
neurodegenerative diseaseDOID:128900.011