Mus musculus

24 known processes

Rsu1

Ras suppressor protein 1

(Aliases: rsp-1)

Rsu1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell adhesionGO:00071553290.161
Human
negative regulation of molecular functionGO:00440922580.114
Fly
blood coagulationGO:0007596760.113
macromolecule catabolic processGO:00090572810.102
hemostasisGO:0007599780.100
cellular component assembly involved in morphogenesisGO:00109271390.099
coagulationGO:0050817780.099
regulation of transferase activityGO:00513382630.098
Fly
wound healingGO:00420601570.098
regulation of body fluid levelsGO:00508781620.098
skeletal muscle organ developmentGO:00605381630.094
regulation of hydrolase activityGO:00513362460.082
Human
negative regulation of protein metabolic processGO:00512482820.080
Fly
actin cytoskeleton organizationGO:00300362200.077
protein catabolic processGO:00301632210.075
muscle system processGO:00030121410.070
myosin filament assemblyGO:003103420.069
regulation of cell substrate adhesionGO:0010810730.069
Human
nucleobase containing small molecule metabolic processGO:00550863520.069
Human
blood circulationGO:00080151950.068
muscle cell differentiationGO:00426922610.068
striated muscle contractionGO:0006941450.065
striated muscle tissue developmentGO:00147062930.063
muscle contractionGO:00069361010.063
cell type specific apoptotic processGO:00972852680.062
regulation of cell cycleGO:00517262810.061
regulation of system processGO:00440572000.060
regulation of cell motilityGO:20001452360.056
muscle tissue developmentGO:00605373080.055
striated muscle cell developmentGO:00550021250.055
metal ion homeostasisGO:00550651890.055
muscle fiber developmentGO:0048747760.055
circulatory system processGO:00030131970.054
peptidyl amino acid modificationGO:00181933360.054
engulfment of apoptotic cellGO:004365230.054
multicellular organismal signalingGO:0035637910.052
negative regulation of protein modification processGO:00314001630.052
Fly
regulation of bindingGO:00510981110.051
regulation of protein serine threonine kinase activityGO:00719001570.051
Fly
ribose phosphate metabolic processGO:00196932910.049
Human
heart processGO:0003015940.049
regulation of organelle organizationGO:00330432890.048
purine nucleotide metabolic processGO:00061633020.047
Human
regulation of cell cycle processGO:00105641600.047
fibrinolysisGO:004273030.046
cation transportGO:00068123990.046
regulation of protein kinase activityGO:00458592320.045
Fly
positive regulation of cellular amino acid metabolic processGO:004576430.045
response to transforming growth factor betaGO:0071559880.045
carboxylic acid transportGO:00469421000.045
negative regulation of phosphorus metabolic processGO:00105631840.044
Fly
regulation of cell migrationGO:00303342190.044
substrate adhesion dependent cell spreadingGO:0034446300.044
glycosyl compound metabolic processGO:19016572460.044
Human
regulation of heart contractionGO:0008016770.042
cell matrix adhesionGO:0007160680.042
extracellular structure organizationGO:00430621480.041
small gtpase mediated signal transductionGO:0007264970.041
cell substrate adhesionGO:00315891300.040
Human
regulation of membrane potentialGO:00423911920.040
calcium ion homeostasisGO:00550741270.040
cellular amino acid metabolic processGO:00065201030.040
heart contractionGO:0060047930.039
regulation of cell adhesionGO:00301551540.039
Human
negative regulation of phosphorylationGO:00423261660.038
Fly
nucleoside phosphate metabolic processGO:00067533380.038
Human
sensory perceptionGO:00076002450.038
ribonucleotide catabolic processGO:00092612080.037
Human
divalent inorganic cation homeostasisGO:00725071380.037
cellular amine metabolic processGO:0044106440.036
organelle assemblyGO:00709251770.035
positive regulation of programmed cell deathGO:00430682180.035
myosin filament organizationGO:003103330.035
purine nucleoside metabolic processGO:00422782410.034
Human
t cell activationGO:00421102890.034
regulation of map kinase activityGO:00434051200.034
Fly
membrane organizationGO:00610242450.034
regulation of actin filament based processGO:0032970990.033
dna metabolic processGO:00062593030.033
canonical wnt signaling pathwayGO:00600701300.033
cation homeostasisGO:00550802120.033
anion transportGO:00068201770.033
blood vessel morphogenesisGO:00485142850.033
muscle cell developmentGO:00550011330.032
striated muscle myosin thick filament assemblyGO:007168810.032
cellular calcium ion homeostasisGO:00068741190.032
action potentialGO:0001508780.032
immune effector processGO:00022523210.031
calcium ion transportGO:00068161590.031
regulation of neutrophil apoptotic processGO:003302910.031
negative regulation of protein phosphorylationGO:00019331260.031
Fly
extracellular fibril organizationGO:004320620.031
positive regulation of cellular amine metabolic processGO:003324050.030
single organismal cell cell adhesionGO:00163371310.030
ubiquitin dependent protein catabolic processGO:00065111290.030
mapk cascadeGO:00001652810.029
Fly
protein processingGO:00164851630.029
skeletal muscle fiber developmentGO:0048741580.029
divalent inorganic cation transportGO:00725111780.029
positive regulation of apoptotic processGO:00430652170.029
nucleotide metabolic processGO:00091173320.029
Human
positive regulation of cell adhesionGO:0045785800.029
Human
negative regulation of phosphate metabolic processGO:00459361840.029
Fly
regulation of cell activationGO:00508652890.029
regulation of proteolysisGO:00301621640.028
negative regulation of cell proliferationGO:00082852960.028
protein maturationGO:00516041760.028
positive regulation of cell deathGO:00109422240.028
homeostasis of number of cellsGO:00488722100.028
regulation of homeostatic processGO:00328441820.027
organic anion transportGO:00157111370.027
rho protein signal transductionGO:0007266320.027
regulation of protein transportGO:00512231630.027
regulation of response to woundingGO:19030341890.027
myotube differentiationGO:00149021050.027
cellular homeostasisGO:00197252400.027
positive regulation of neutrophil apoptotic processGO:003303110.026
positive regulation of homeostatic processGO:0032846640.026
positive regulation of nucleotide metabolic processGO:00459811140.026
Human
negative regulation of intracellular signal transductionGO:19025321670.026
Fly
positive regulation of cell developmentGO:00107202370.026
regulation of cellular amine metabolic processGO:0033238200.026
transmission of nerve impulseGO:0019226760.026
extrinsic apoptotic signaling pathwayGO:00971911260.026
regulation of defense responseGO:00313472330.026
digestive system developmentGO:00551232000.026
posttranscriptional regulation of gene expressionGO:00106081550.026
divalent metal ion transportGO:00708381720.025
single organism cell adhesionGO:00986021560.025
cellular metal ion homeostasisGO:00068751510.025
angiogenesisGO:00015252010.025
lipid localizationGO:00108761260.025
regulation of neuron deathGO:19012141340.025
wnt signaling pathwayGO:00160551880.025
maintenance of locationGO:0051235890.025
positive regulation of protein phosphorylationGO:00019342420.024
regulation of blood circulationGO:1903522930.024
regulation of nucleotide metabolic processGO:00061401690.024
Human
cellular response to acid chemicalGO:0071229680.024
sequestering of calcium ionGO:0051208180.024
asymmetric neuroblast divisionGO:005505910.024
ion transmembrane transportGO:00342203610.024
regulation of secretionGO:00510462740.023
apoptotic signaling pathwayGO:00971903060.023
sensory perception of mechanical stimulusGO:00509541070.023
leukocyte homeostasisGO:0001776790.023
extracellular matrix organizationGO:00301981470.023
neuron deathGO:00709971540.023
epidermis developmentGO:00085441870.023
mitotic cell cycle processGO:19030471590.023
positive regulation of protein serine threonine kinase activityGO:00719021060.023
positive regulation of cellular catabolic processGO:00313311480.023
Human
positive regulation of protein modification processGO:00314012990.023
regulation of mapk cascadeGO:00434082480.023
Fly
regulation of cellular amino acid metabolic processGO:000652150.022
regulation of muscle system processGO:0090257800.022
homotypic cell cell adhesionGO:0034109280.022
digestive tract developmentGO:00485651900.022
cardiac muscle tissue developmentGO:00487381300.022
cardiac muscle contractionGO:0060048320.022
regulation of wnt signaling pathwayGO:00301111230.022
neuronal action potentialGO:0019228540.022
ossificationGO:00015032160.022
protein localization to organelleGO:00333651850.022
purine nucleoside catabolic processGO:00061522050.022
Human
endocytosisGO:00068971680.022
actin filament based movementGO:0030048230.022
monocarboxylic acid transportGO:0015718440.022
gastrulationGO:00073691160.022
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.022
organonitrogen compound catabolic processGO:19015652640.022
Human
regulation of protein localizationGO:00328802310.022
response to growth factorGO:00708481980.021
regulation of protein stabilityGO:0031647520.021
organonitrogen compound biosynthetic processGO:19015661920.021
epithelial tube morphogenesisGO:00605623030.021
morphogenesis of a branching epitheliumGO:00611381930.021
myeloid cell differentiationGO:00300992330.021
ras protein signal transductionGO:0007265770.021
regulation of neuron apoptotic processGO:00435231220.021
negative regulation of cellular protein metabolic processGO:00322692470.021
Fly
proteolysis involved in cellular protein catabolic processGO:00516031470.021
intracellular protein transportGO:00068862040.021
cellular response to growth factor stimulusGO:00713631970.021
cell junction organizationGO:0034330770.021
positive regulation of cell substrate adhesionGO:0010811470.020
Human
negative regulation of cellular component organizationGO:00511291940.020
organic acid transportGO:00158491010.020
amine metabolic processGO:0009308450.020
inorganic ion transmembrane transportGO:00986602340.020
positive regulation of secretionGO:00510471300.020
response to acid chemicalGO:00011011110.020
ameboidal type cell migrationGO:00016671280.020
platelet activationGO:0030168400.020
regulation of striated muscle cell differentiationGO:0051153810.020
small molecule biosynthetic processGO:00442831320.020
negative regulation of immune system processGO:00026832090.020
nucleoside triphosphate metabolic processGO:00091412300.019
Human
neuron apoptotic processGO:00514021420.019
multicellular organismal homeostasisGO:00488711640.019
regulation of kinase activityGO:00435492490.019
Fly
nuclear transportGO:00511691390.019
peptidyl serine phosphorylationGO:0018105740.019
response to organic cyclic compoundGO:00140701980.019
positive regulation of proteolysisGO:0045862850.019
cardiac chamber developmentGO:00032051080.019
cellular ketone metabolic processGO:0042180840.019
regulation of wound healingGO:0061041400.019
transmembrane transportGO:00550854120.018
regulation of muscle contractionGO:0006937490.018
regulation of cytoskeleton organizationGO:00514931220.018
regulation of mitotic cell cycle phase transitionGO:1901990730.018
mitotic cell cycleGO:00002781950.018
positive regulation of cell motilityGO:20001471160.018
leukocyte apoptotic processGO:0071887710.018
positive regulation of myeloid cell apoptotic processGO:003303440.018
regulation of intracellular transportGO:00323861590.018
axonogenesisGO:00074092740.018
cellular protein catabolic processGO:00442571550.018
positive regulation of gtpase activityGO:0043547850.018
Human
regulation of protein catabolic processGO:00421761080.018
positive regulation of kinase activityGO:00336741550.018
regulation of integrin mediated signaling pathwayGO:200104480.018
plasma membrane organizationGO:0007009900.018
negative regulation of phagocytosisGO:005076540.018
protein kinase b signalingGO:0043491740.018
regulation of cellular ketone metabolic processGO:0010565660.018
signal transduction in absence of ligandGO:0038034550.017
myeloid cell homeostasisGO:00022621140.017
defense response to bacteriumGO:00427421190.017
organophosphate biosynthetic processGO:00904071220.017
cytokine productionGO:00018163190.017
multicellular organism growthGO:00352641610.017
actin filament organizationGO:00070151130.017
cellular lipid metabolic processGO:00442553230.017
protein oligomerizationGO:0051259670.017
regulation of actin cytoskeleton organizationGO:0032956840.017
nucleoside phosphate catabolic processGO:19012922220.017
Human
myoblast differentiationGO:0045445520.017
purine ribonucleoside triphosphate catabolic processGO:00092071990.017
Human
cellular macromolecule catabolic processGO:00442652060.017
regionalizationGO:00030023370.016
regulation of t cell activationGO:00508631700.016
cellular protein complex assemblyGO:00436231160.016
lipid transportGO:0006869980.016
carboxylic acid biosynthetic processGO:0046394860.016
positive regulation of protein kinase activityGO:00458601440.016
neural precursor cell proliferationGO:00613511210.016
cellular water homeostasisGO:000999220.016
endomembrane system organizationGO:00102561470.016
regulation of hemostasisGO:1900046280.016
leukocyte migrationGO:00509001240.016
response to molecule of bacterial originGO:00022371430.016
establishment or maintenance of cell polarityGO:0007163860.016
glial cell differentiationGO:00100011310.016
regulation of cell divisionGO:0051302760.016
regulation of cytoplasmic transportGO:19036491120.016
connective tissue developmentGO:00614481790.016
cation transmembrane transportGO:00986552660.016
regulation of leukocyte apoptotic processGO:2000106560.016
organophosphate catabolic processGO:00464342320.016
Human
purine ribonucleoside metabolic processGO:00461282410.016
Human
organic cyclic compound catabolic processGO:19013612950.016
Human
sequestering of metal ionGO:0051238190.016
regulation of ion transportGO:00432692150.015
guanosine containing compound catabolic processGO:19010691440.015
Human
cell divisionGO:00513011200.015
regulation of cell projection organizationGO:00313442060.015
regulation of nucleoside metabolic processGO:00091181300.015
Human
positive regulation of cell migrationGO:00303351090.015
cilium morphogenesisGO:00602711020.015
cellular divalent inorganic cation homeostasisGO:00725031270.015
protein importGO:00170381010.015
tissue homeostasisGO:00018941150.015
cellular ion homeostasisGO:00068731650.015
forebrain developmentGO:00309003020.015
early endosome to late endosome transportGO:004502220.015
regulation of skeletal muscle fiber developmentGO:0048742360.015
morphogenesis of a branching structureGO:00017632030.015
negative regulation of cell developmentGO:00107211690.015
cell fate commitmentGO:00451652100.015
carbohydrate derivative biosynthetic processGO:19011371830.015
g protein coupled receptor signaling pathwayGO:00071862430.014
peptidyl serine modificationGO:0018209830.014
protein targetingGO:00066051430.014
positive regulation of bindingGO:0051099490.014
positive regulation of intracellular transportGO:0032388700.014
branching morphogenesis of an epithelial tubeGO:00487541590.014
inorganic cation transmembrane transportGO:00986622070.014
regulation of protein maturationGO:1903317960.014
nitrogen compound transportGO:00717052710.014
learning or memoryGO:00076111480.014
positive regulation of hydrolase activityGO:00513451480.014
Human
negative regulation of response to woundingGO:1903035770.014
icosanoid transportGO:0071715140.014
regulation of ossificationGO:00302781120.014
defense response to other organismGO:00985421970.014
acid secretionGO:0046717330.014
cytoplasmic transportGO:00164822340.014
heart morphogenesisGO:00030071780.014
carbohydrate derivative catabolic processGO:19011362310.014
Human
tube formationGO:00351481400.014
nucleocytoplasmic transportGO:00069131390.014
regulation of transmembrane transportGO:00347621280.014
cellular chemical homeostasisGO:00550822150.014
epithelial cell developmentGO:00020641590.014
cellular response to lipidGO:00713961450.014
compound eye developmentGO:004874910.014
positive regulation of protein transportGO:0051222930.014
neutrophil apoptotic processGO:000178130.014
cellular response to abiotic stimulusGO:0071214560.014
sensory perception of soundGO:0007605970.014
i kappab kinase nf kappab signalingGO:0007249850.014
lamellipodium organizationGO:0097581290.014
lymphocyte differentiationGO:00300982420.014
myotube cell developmentGO:0014904600.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.013
axon ensheathmentGO:0008366760.013
regulation of hormone levelsGO:00108172110.013
g1 s transition of mitotic cell cycleGO:0000082570.013
focal adhesion assemblyGO:0048041190.013
nuclear divisionGO:00002801580.013
hormone secretionGO:00468791280.013
myofibril assemblyGO:0030239340.013
positive regulation of secretion by cellGO:19035321140.013
telencephalon developmentGO:00215371860.013
cellular response to hormone stimulusGO:00328701500.013
actin mediated cell contractionGO:0070252150.013
leukocyte differentiationGO:00025213420.013
ribonucleotide metabolic processGO:00092592910.013
Human
gland developmentGO:00487323300.013
cardiac muscle cell differentiationGO:0055007690.013
nucleoside catabolic processGO:00091642060.013
Human
microtubule based processGO:00070172360.013
activation of immune responseGO:00022531380.013
fatty acid transportGO:0015908280.013
multi multicellular organism processGO:00447061090.013
cellular response to organonitrogen compoundGO:00714171450.013
asymmetric stem cell divisionGO:009872230.013
gliogenesisGO:00420631410.013
regulation of protein targetingGO:1903533610.013
purine nucleoside triphosphate metabolic processGO:00091442260.013
Human
regulation of cellular catabolic processGO:00313292420.013
Human
immune response regulating signaling pathwayGO:00027641250.013
carbohydrate homeostasisGO:00335001280.013
negative regulation of smooth muscle cell migrationGO:001491220.013
cell growthGO:00160491300.013
positive regulation of nervous system developmentGO:00519622210.013
negative regulation of neuron apoptotic processGO:0043524920.013
organic acid biosynthetic processGO:0016053860.013
spermatogenesisGO:00072832840.013
positive regulation of map kinase activityGO:0043406840.013
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.013
protein localization to plasma membraneGO:0072659570.013
cellular nitrogen compound catabolic processGO:00442702800.013
Human
somitogenesisGO:0001756690.012
ribonucleoside catabolic processGO:00424542060.012
Human
regulation of mitotic cell cycleGO:00073461260.012
regulation of canonical wnt signaling pathwayGO:0060828820.012
nucleoside metabolic processGO:00091162460.012
Human
response to organonitrogen compoundGO:00102432460.012
purine containing compound metabolic processGO:00725213110.012
Human
lymphocyte proliferationGO:00466511640.012
negative regulation of organelle organizationGO:0010639900.012
neuron migrationGO:00017641220.012
response to peptide hormoneGO:00434341270.012
cytokinetic processGO:003250620.012
actin filament polymerizationGO:0030041440.012
glycoprotein metabolic processGO:00091001160.012
regulation of protein bindingGO:0043393600.012
regulation of metal ion transportGO:00109591060.012
gtp metabolic processGO:00460391440.012
Human
regulation of muscle tissue developmentGO:1901861970.012
response to extracellular stimulusGO:00099911270.012
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.012
regulation of neuron differentiationGO:00456642810.012
regulation of nucleotide catabolic processGO:00308111220.012
Human
myelinationGO:0042552740.012
regulation of peptidase activityGO:0052547960.012
immune response regulating cell surface receptor signaling pathwayGO:0002768800.012
inflammatory responseGO:00069542440.012
heterocycle catabolic processGO:00467002800.012
Human
regulation of coagulationGO:0050818310.012
protein modification by small protein conjugationGO:00324461870.012
regulation of sequence specific dna binding transcription factor activityGO:00510901060.012
protein localization to membraneGO:00726571080.012
negative regulation of neuron deathGO:1901215980.012
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.012
retrograde transport endosome to golgiGO:004214720.012
positive regulation of b cell receptor signaling pathwayGO:005086140.012
embryonic organ morphogenesisGO:00485622760.012
fat soluble vitamin biosynthetic processGO:004236240.012
oxidation reduction processGO:00551143420.012
positive regulation of nucleotide catabolic processGO:0030813880.012
Human
regulation of blood pressureGO:0008217930.012
ribonucleoside metabolic processGO:00091192450.012
Human
chemotaxisGO:00069352470.011
positive regulation of canonical wnt signaling pathwayGO:0090263290.011
regulation of ras protein signal transductionGO:00465781140.011
lipid biosynthetic processGO:00086101790.011
alpha beta t cell activationGO:0046631910.011
regulation of multi organism processGO:00439001110.011
regulation of endopeptidase activityGO:0052548890.011
meiotic cell cycleGO:00513211220.011
fat cell differentiationGO:00454441600.011
response to lipopolysaccharideGO:00324961280.011
skin developmentGO:00435882200.011
modification dependent macromolecule catabolic processGO:00436321330.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
Human
integrin mediated signaling pathwayGO:0007229270.011
Fly
meiotic nuclear divisionGO:00071261150.011
positive regulation of cytosolic calcium ion concentrationGO:0007204650.011
cell activation involved in immune responseGO:00022631260.011
regulation of myoblast differentiationGO:0045661290.011
cytosolic calcium ion transportGO:0060401480.011
protein localization to nucleusGO:00345041210.011
cognitionGO:00508901490.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
regulation of intracellular protein transportGO:0033157820.011
response to inorganic substanceGO:0010035960.011
regulation of calcium ion transport into cytosolGO:0010522310.011
epithelial cell morphogenesisGO:0003382410.011
single fertilizationGO:0007338820.011
regulation of blood coagulationGO:0030193280.011
purine ribonucleotide metabolic processGO:00091502900.011
Human
regulation of purine nucleotide metabolic processGO:19005421690.011
Human
immune response activating signal transductionGO:00027571160.011
innate immune responseGO:00450871570.011
regulation of lymphocyte activationGO:00512492400.011
regulation of protein processingGO:0070613960.011
cellular response to cytokine stimulusGO:00713451890.011
glycosyl compound catabolic processGO:19016582060.011
Human
cellular response to biotic stimulusGO:0071216920.011
regulation of establishment of protein localizationGO:00702011810.011
mitotic cytokinesisGO:000028140.011
regulation of g1 s transition of mitotic cell cycleGO:2000045350.011
positive regulation of transferase activityGO:00513471670.011
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.011
negative regulation of calcium ion transmembrane transporter activityGO:190102010.011
ear developmentGO:00435832000.011
negative regulation of cell adhesionGO:0007162450.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
Human
regulation of neuron projection developmentGO:00109751690.011
peripheral nervous system developmentGO:0007422530.011
regulation of endocytosisGO:0030100690.011
neural tube formationGO:00018411080.011
microtubule cytoskeleton organizationGO:00002261570.011
reactive nitrogen species metabolic processGO:200105700.010
positive regulation of lymphocyte activationGO:00512511400.010
positive regulation of cell cycle processGO:0090068610.010
protein import into nucleusGO:0006606950.010
fibroblast migrationGO:0010761210.010
sprouting angiogenesisGO:0002040260.010
cytosolic calcium ion homeostasisGO:0051480700.010
cell cycle g1 s phase transitionGO:0044843570.010
immune response activating cell surface receptor signaling pathwayGO:0002429720.010
male gamete generationGO:00482322850.010
positive regulation of cytoplasmic transportGO:1903651400.010
positive regulation of g1 s transition of mitotic cell cycleGO:190008790.010
b cell receptor signaling pathwayGO:0050853200.010
fatty acid derivative transportGO:1901571140.010
locomotory behaviorGO:00076261950.010
regulation of cellular response to growth factor stimulusGO:0090287820.010
modification dependent protein catabolic processGO:00199411330.010
single organism nuclear importGO:1902593950.010
neural tube developmentGO:00219151600.010
positive regulation of integrin mediated signaling pathwayGO:200104650.010
sphingolipid metabolic processGO:0006665450.010

Rsu1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.027
connective tissue diseaseDOID:6500.027
musculoskeletal system diseaseDOID:1700.027
nervous system diseaseDOID:86300.015
congenital nervous system abnormalityDOID:249000.014
physical disorderDOID:008001500.014
bone diseaseDOID:008000100.010