Mus musculus

0 known processes

Trim5

tripartite motif-containing 5

(Aliases: EG667823,Gm8833)

Trim5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of nlrp3 inflammasome complex assemblyGO:190022620.271
Mouse
defense response to other organismGO:00985421970.205
Mouse
immune effector processGO:00022523210.162
Mouse
innate immune responseGO:00450871570.159
Human Mouse
regulation of defense responseGO:00313472330.158
Human Mouse
regulation of nlrp3 inflammasome complex assemblyGO:190022540.154
Mouse
positive regulation of viral genome replicationGO:004507020.101
Mouse
response to molecule of bacterial originGO:00022371430.098
Human
immune response regulating signaling pathwayGO:00027641250.096
Human Mouse
positive regulation of innate immune responseGO:0045089800.095
Human Mouse
regulation of innate immune responseGO:0045088910.094
Human Mouse
positive regulation of viral entry into host cellGO:004659830.092
Mouse
regulation of cytokine productionGO:00018172660.091
Mouse
cellular response to lipopolysaccharideGO:0071222770.088
Human
cytokine productionGO:00018163190.084
Mouse
immune response activating signal transductionGO:00027571160.082
Human Mouse
regulation of hydrolase activityGO:00513362460.079
positive regulation of defense responseGO:00313491240.075
Human Mouse
protein modification by small protein conjugation or removalGO:00706472070.073
Human Mouse
pattern recognition receptor signaling pathwayGO:0002221470.072
Human Mouse
cellular macromolecule catabolic processGO:00442652060.070
Mouse
mapk cascadeGO:00001652810.069
Human
cellular response to molecule of bacterial originGO:0071219830.065
Human
myeloid cell differentiationGO:00300992330.063
Mouse
response to lipopolysaccharideGO:00324961280.062
Human
activation of immune responseGO:00022531380.062
Human Mouse
cellular response to biotic stimulusGO:0071216920.062
Human
cellular response to lipidGO:00713961450.062
Human
entry into cell of other organism involved in symbiotic interactionGO:0051806150.061
Human Mouse
protein ubiquitinationGO:00165671710.059
Human Mouse
viral gene expressionGO:001908030.056
Mouse
heterocycle catabolic processGO:00467002800.054
aromatic compound catabolic processGO:00194392860.054
proteolysis involved in cellular protein catabolic processGO:00516031470.053
Mouse
cellular nitrogen compound catabolic processGO:00442702800.053
negative regulation of molecular functionGO:00440922580.053
activation of innate immune responseGO:0002218560.053
Human Mouse
protein modification by small protein conjugationGO:00324461870.052
Human Mouse
organic cyclic compound catabolic processGO:19013612950.052
ras protein signal transductionGO:0007265770.049
reactive oxygen species metabolic processGO:0072593840.049
Mouse
cellular amino acid metabolic processGO:00065201030.048
cellular amine metabolic processGO:0044106440.047
regulation of cellular ketone metabolic processGO:0010565660.046
regulation of cellular component biogenesisGO:00440871810.045
Mouse
regulation of interleukin 6 productionGO:0032675550.045
Mouse
nucleoside phosphate catabolic processGO:19012922220.044
negative regulation of viral transcriptionGO:003289730.044
Mouse
negative regulation of cellular component organizationGO:00511291940.044
Mouse
positive regulation of cytokine productionGO:00018191740.043
negative regulation of immune system processGO:00026832090.043
Mouse
cellular protein catabolic processGO:00442571550.043
Mouse
nucleobase containing small molecule metabolic processGO:00550863520.043
regulation of mapk cascadeGO:00434082480.042
Human
nucleoside phosphate metabolic processGO:00067533380.042
movement in environment of other organism involved in symbiotic interactionGO:0052192150.039
Human Mouse
macromolecule catabolic processGO:00090572810.039
Mouse
symbiosis encompassing mutualism through parasitismGO:0044403830.039
Human Mouse
negative regulation of protein metabolic processGO:00512482820.039
regulation of multi organism processGO:00439001110.039
Human Mouse
organophosphate catabolic processGO:00464342320.038
entry into host cellGO:0030260150.038
Human Mouse
small gtpase mediated signal transductionGO:0007264970.037
purine ribonucleoside catabolic processGO:00461302050.037
glycosyl compound metabolic processGO:19016572460.037
modification dependent macromolecule catabolic processGO:00436321330.036
Mouse
defense response to virusGO:0051607680.036
Mouse
cellular protein complex assemblyGO:00436231160.036
Mouse
purine containing compound metabolic processGO:00725213110.036
nucleoside triphosphate metabolic processGO:00091412300.036
nucleotide metabolic processGO:00091173320.035
viral processGO:0016032410.035
Human Mouse
cellular ketone metabolic processGO:0042180840.035
purine nucleotide metabolic processGO:00061633020.035
purine ribonucleoside metabolic processGO:00461282410.035
i kappab kinase nf kappab signalingGO:0007249850.035
Human
regulation of cell activationGO:00508652890.035
negative regulation of defense responseGO:0031348770.035
Mouse
positive regulation of mapk cascadeGO:00434101700.035
Human
regulation of actin nucleationGO:005112540.034
nucleotide catabolic processGO:00091662170.034
interleukin 6 productionGO:0032635580.034
Mouse
purine nucleoside triphosphate catabolic processGO:00091462030.034
amine metabolic processGO:0009308450.034
modification dependent protein catabolic processGO:00199411330.033
Mouse
purine nucleoside metabolic processGO:00422782410.032
ribonucleoside metabolic processGO:00091192450.032
regulation of reactive oxygen species metabolic processGO:2000377400.032
Mouse
regulation of cellular amine metabolic processGO:0033238200.032
purine ribonucleotide metabolic processGO:00091502900.032
apoptotic signaling pathwayGO:00971903060.032
negative regulation of cellular protein metabolic processGO:00322692470.032
protein processingGO:00164851630.032
actin cytoskeleton organizationGO:00300362200.032
homeostasis of number of cellsGO:00488722100.032
Mouse
purine ribonucleoside triphosphate metabolic processGO:00092052200.031
glycosyl compound catabolic processGO:19016582060.031
erythrocyte differentiationGO:0030218880.031
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.031
nucleoside metabolic processGO:00091162460.031
viral transcriptionGO:001908330.031
Mouse
regulation of cellular amino acid metabolic processGO:000652150.031
regulation of viral transcriptionGO:004678230.031
Mouse
carbohydrate derivative catabolic processGO:19011362310.031
proteasomal protein catabolic processGO:0010498980.030
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092071990.030
purine nucleotide catabolic processGO:00061952110.030
regulation of organelle organizationGO:00330432890.030
purine containing compound catabolic processGO:00725232130.030
protein catabolic processGO:00301632210.029
Mouse
rho protein signal transductionGO:0007266320.029
ribonucleoside catabolic processGO:00424542060.029
protein maturationGO:00516041760.029
cellular response to cytokine stimulusGO:00713451890.029
ribose phosphate metabolic processGO:00196932910.029
ossificationGO:00015032160.029
purine nucleoside triphosphate metabolic processGO:00091442260.029
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.029
Human Mouse
tumor necrosis factor productionGO:0032640500.028
Mouse
regulation of cellular component sizeGO:00325351210.028
negative regulation of nervous system developmentGO:00519611560.028
Mouse
nucleoside catabolic processGO:00091642060.028
regulation of lymphocyte activationGO:00512492400.028
positive regulation of actin nucleationGO:005112730.028
positive regulation of cellular amine metabolic processGO:003324050.027
negative regulation of viral entry into host cellGO:0046597100.027
Human Mouse
cell type specific apoptotic processGO:00972852680.027
myeloid cell homeostasisGO:00022621140.026
Mouse
negative regulation of phosphate metabolic processGO:00459361840.026
ubiquitin dependent protein catabolic processGO:00065111290.026
Mouse
ribonucleoside triphosphate catabolic processGO:00092031990.026
entry into hostGO:0044409150.026
Human Mouse
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.026
Mouse
interferon beta productionGO:0032608160.026
Mouse
purine ribonucleotide catabolic processGO:00091542080.025
regulation of protein complex assemblyGO:0043254830.025
Mouse
ribonucleotide catabolic processGO:00092612080.025
regulation of anatomical structure sizeGO:00900661780.025
protein polyubiquitinationGO:0000209330.025
Human Mouse
carbohydrate derivative biosynthetic processGO:19011371830.025
organonitrogen compound catabolic processGO:19015652640.025
ribonucleoside triphosphate metabolic processGO:00091992200.025
positive regulation of protein modification processGO:00314012990.025
dna metabolic processGO:00062593030.024
purine nucleoside catabolic processGO:00061522050.024
positive regulation of hydrolase activityGO:00513451480.024
regulation of cellular catabolic processGO:00313292420.023
cation transportGO:00068123990.023
regulation of defense response to virusGO:0050688180.023
Mouse
protein oligomerizationGO:0051259670.023
Human
negative regulation of hydrolase activityGO:0051346710.023
regulation of secretion by cellGO:19035302490.023
transmembrane transportGO:00550854120.023
cellular lipid metabolic processGO:00442553230.022
regulation of response to biotic stimulusGO:0002831380.022
Human Mouse
muscle cell differentiationGO:00426922610.022
inflammatory responseGO:00069542440.022
positive regulation of programmed cell deathGO:00430682180.022
spermatogenesisGO:00072832840.022
cell adhesionGO:00071553290.021
regulation of actin filament based processGO:0032970990.021
regulation of transferase activityGO:00513382630.021
actin filament organizationGO:00070151130.021
regulation of protein localizationGO:00328802310.021
actin filament polymerizationGO:0030041440.021
response to organonitrogen compoundGO:00102432460.021
regulation of proteolysisGO:00301621640.021
ribonucleotide metabolic processGO:00092592910.021
posttranscriptional regulation of gene expressionGO:00106081550.021
protein polymerizationGO:0051258570.021
regulation of ion transportGO:00432692150.020
tumor necrosis factor superfamily cytokine productionGO:0071706510.020
Mouse
regulation of endopeptidase activityGO:0052548890.020
cation transmembrane transportGO:00986552660.020
guanosine containing compound metabolic processGO:19010681440.020
type i interferon productionGO:0032606290.020
Mouse
negative regulation of cytokine productionGO:0001818840.020
Mouse
nucleoside triphosphate catabolic processGO:00091432050.020
t cell activationGO:00421102890.020
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.020
Human
male gamete generationGO:00482322850.020
actin polymerization or depolymerizationGO:0008154540.020
regulation of kinase activityGO:00435492490.020
anion transportGO:00068201770.020
oxidation reduction processGO:00551143420.020
negative regulation of cell proliferationGO:00082852960.019
innate immune response activating signal transductionGO:0002758500.019
Human Mouse
negative regulation of phosphorus metabolic processGO:00105631840.019
cytoplasmic transportGO:00164822340.019
regulation of reactive oxygen species biosynthetic processGO:190342620.019
regulation of cysteine type endopeptidase activityGO:2000116650.019
peptidyl amino acid modificationGO:00181933360.019
hematopoietic progenitor cell differentiationGO:00022441430.019
gtp catabolic processGO:00061841430.018
lymphocyte mediated immunityGO:00024491390.018
positive regulation of organelle organizationGO:00106381280.018
organonitrogen compound biosynthetic processGO:19015661920.018
negative regulation of cellular amine metabolic processGO:003323910.018
nitrogen compound transportGO:00717052710.018
leukocyte differentiationGO:00025213420.018
intracellular protein transportGO:00068862040.018
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.018
Mouse
positive regulation of cellular catabolic processGO:00313311480.018
muscle tissue developmentGO:00605373080.018
regulation of secretionGO:00510462740.018
regulation of leukocyte mediated immunityGO:00027031040.018
regulation of apoptotic signaling pathwayGO:20012331970.018
viral genome replicationGO:0019079170.018
Mouse
regulation of protein processingGO:0070613960.017
guanosine containing compound catabolic processGO:19010691440.017
interaction with hostGO:0051701220.017
Human Mouse
organelle localizationGO:00516401790.017
multicellular organismal homeostasisGO:00488711640.017
membrane organizationGO:00610242450.017
regulation of response to woundingGO:19030341890.017
endocytosisGO:00068971680.017
carbohydrate metabolic processGO:00059752300.017
regulation of peptidase activityGO:0052547960.017
synaptic transmissionGO:00072683290.017
regulation of interferon beta productionGO:0032648130.017
Mouse
cell activation involved in immune responseGO:00022631260.017
nucleocytoplasmic transportGO:00069131390.016
regulation of establishment of protein localizationGO:00702011810.016
regulation of nucleoside metabolic processGO:00091181300.016
cellular homeostasisGO:00197252400.016
ion transmembrane transportGO:00342203610.016
negative regulation of viral processGO:0048525230.016
Human Mouse
negative regulation of immune effector processGO:0002698550.016
Mouse
lymphocyte proliferationGO:00466511640.016
leukocyte proliferationGO:00706611720.016
positive regulation of protein phosphorylationGO:00019342420.016
regulation of tumor necrosis factor productionGO:0032680490.016
Mouse
regulation of gtp catabolic processGO:00331241130.016
regulation of nucleotide catabolic processGO:00308111220.016
protein localization to organelleGO:00333651850.016
negative regulation of phosphorylationGO:00423261660.016
positive regulation of secretionGO:00510471300.016
regulation of protein transportGO:00512231630.016
regulation of nucleotide metabolic processGO:00061401690.016
g protein coupled receptor signaling pathwayGO:00071862430.016
entry into other organism involved in symbiotic interactionGO:0051828150.016
Human Mouse
lymphocyte differentiationGO:00300982420.016
establishment of protein localization to organelleGO:00725941180.015
regulation of purine nucleotide metabolic processGO:19005421690.015
regulation of inflammatory responseGO:00507271470.015
compound eye developmentGO:004874910.015
gtp metabolic processGO:00460391440.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
positive regulation of cell deathGO:00109422240.015
regulation of ossificationGO:00302781120.015
positive regulation of secretion by cellGO:19035321140.015
fat cell differentiationGO:00454441600.015
regulation of purine nucleotide catabolic processGO:00331211220.015
positive regulation of gtpase activityGO:0043547850.015
regulation of protein maturationGO:1903317960.015
glycoprotein biosynthetic processGO:0009101890.015
positive regulation of cell developmentGO:00107202370.015
positive regulation of protein transportGO:0051222930.015
positive regulation of gtp catabolic processGO:0033126850.015
mitotic cell cycleGO:00002781950.015
blood vessel morphogenesisGO:00485142850.015
positive regulation of cellular component biogenesisGO:0044089940.015
inorganic cation transmembrane transportGO:00986622070.015
regulation of body fluid levelsGO:00508781620.015
epithelial tube morphogenesisGO:00605623030.015
positive regulation of apoptotic processGO:00430652170.014
regulation of actin filament lengthGO:0030832450.014
positive regulation of immune effector processGO:00026991070.014
regulation of cell cycleGO:00517262810.014
regulation of cell motilityGO:20001452360.014
positive regulation of nf kappab transcription factor activityGO:0051092300.014
Human
regulation of cytoskeleton organizationGO:00514931220.014
leukocyte mediated immunityGO:00024431740.014
regulation of protein kinase activityGO:00458592320.014
microtubule based processGO:00070172360.014
mitotic cell cycle processGO:19030471590.014
response to organic cyclic compoundGO:00140701980.014
negative regulation of cellular amino acid metabolic processGO:004576300.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
organic hydroxy compound metabolic processGO:19016152030.014
negative regulation of protein processingGO:0010955790.014
protein targetingGO:00066051430.014
positive regulation of purine nucleotide catabolic processGO:0033123880.014
gland developmentGO:00487323300.014
regulation of hormone levelsGO:00108172110.014
regulation of t cell activationGO:00508631700.014
regulation of cell adhesionGO:00301551540.014
negative regulation of protein modification processGO:00314001630.013
positive regulation of nucleotide catabolic processGO:0030813880.013
reactive oxygen species biosynthetic processGO:190340980.013
divalent inorganic cation transportGO:00725111780.013
regulation of membrane potentialGO:00423911920.013
renal system developmentGO:00720012250.013
striated muscle tissue developmentGO:00147062930.013
developmental maturationGO:00217001930.013
tissue homeostasisGO:00018941150.013
reactive nitrogen species metabolic processGO:200105700.013
positive regulation of viral processGO:004852450.013
Mouse
camera type eye developmentGO:00430102660.013
b cell activationGO:00421131610.013
leukocyte activation involved in immune responseGO:00023661260.013
positive regulation of purine nucleotide metabolic processGO:19005441140.013
organophosphate biosynthetic processGO:00904071220.013
retrograde transport endosome to golgiGO:004214720.013
cellular response to organonitrogen compoundGO:00714171450.013
cellular response to hormone stimulusGO:00328701500.013
regulation of actin cytoskeleton organizationGO:0032956840.013
negative regulation of cell developmentGO:00107211690.013
Mouse
positive regulation of nucleotide metabolic processGO:00459811140.013
regulation of lymphocyte mediated immunityGO:0002706840.013
nuclear transportGO:00511691390.013
positive regulation of nervous system developmentGO:00519622210.013
viral entry into host cellGO:0046718150.013
Human Mouse
regulation of neuron differentiationGO:00456642810.013
regulation of cell projection organizationGO:00313442060.013
engulfment of apoptotic cellGO:004365230.013
maintenance of locationGO:0051235890.013
defense response to bacteriumGO:00427421190.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.013
cell substrate adhesionGO:00315891300.013
neuron deathGO:00709971540.013
mitochondrion organizationGO:00070051340.013
sensory organ morphogenesisGO:00905962420.012
regulation of ras protein signal transductionGO:00465781140.012
regulation of protein serine threonine kinase activityGO:00719001570.012
immune response activating cell surface receptor signaling pathwayGO:0002429720.012
negative regulation of proteolysisGO:0045861740.012
divalent metal ion transportGO:00708381720.012
negative regulation of intracellular signal transductionGO:19025321670.012
sensory perceptionGO:00076002450.012
response to radiationGO:00093141650.012
natural killer cell activationGO:0030101440.012
urogenital system developmentGO:00016552610.012
cellular response to dna damage stimulusGO:00069742070.012
circulatory system processGO:00030131970.012
regulation of cell migrationGO:00303342190.012
negative regulation of toll like receptor signaling pathwayGO:0034122140.012
Mouse
protein secretionGO:00093061110.012
regulation of viral entry into host cellGO:0046596120.012
Human Mouse
negative regulation of protein maturationGO:1903318790.012
small molecule biosynthetic processGO:00442831320.012
sequestering of calcium ionGO:0051208180.012
morphogenesis of a branching structureGO:00017632030.012
regulation of toll like receptor signaling pathwayGO:0034121200.012
Mouse
response to acid chemicalGO:00011011110.012
anatomical structure homeostasisGO:00602491450.012
positive regulation of lymphocyte activationGO:00512511400.012
regulation of actin polymerization or depolymerizationGO:0008064450.012
lipopolysaccharide mediated signaling pathwayGO:0031663250.012
Human
extrinsic apoptotic signaling pathwayGO:00971911260.012
regulation of protein catabolic processGO:00421761080.012
Mouse
viral life cycleGO:0019058360.012
Human Mouse
regulation of cellular response to stressGO:00801351590.012
positive regulation of cell activationGO:00508671580.012
positive regulation of transferase activityGO:00513471670.012
movement in host environmentGO:0052126150.012
Human Mouse
kidney developmentGO:00018222130.012
cellular chemical homeostasisGO:00550822150.012
regulation of actin filament polymerizationGO:0030833380.011
epithelial cell proliferationGO:00506731740.011
skeletal system developmentGO:00015013560.011
chemotaxisGO:00069352470.011
positive regulation of reactive oxygen species metabolic processGO:2000379110.011
angiogenesisGO:00015252010.011
ear developmentGO:00435832000.011
establishment of organelle localizationGO:00516561220.011
interspecies interaction between organismsGO:0044419830.011
Human Mouse
positive regulation of proteolysisGO:0045862850.011
endomembrane system organizationGO:00102561470.011
natural killer cell mediated immunityGO:0002228290.011
dephosphorylationGO:00163111290.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
multicellular organismal signalingGO:0035637910.011
extracellular matrix organizationGO:00301981470.011
cation homeostasisGO:00550802120.011
nucleoside monophosphate metabolic processGO:0009123850.011
regulation of lipopolysaccharide mediated signaling pathwayGO:003166490.011
Human
lipid biosynthetic processGO:00086101790.011
organelle assemblyGO:00709251770.011
positive regulation of nucleoside metabolic processGO:0045979910.011
glycoprotein metabolic processGO:00091001160.011
regionalizationGO:00030023370.011
single organism cell adhesionGO:00986021560.011
regulation of interleukin 8 productionGO:003267730.011
sequestering of metal ionGO:0051238190.011
myeloid leukocyte differentiationGO:00025731190.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
response to peptideGO:19016521360.011
inorganic ion transmembrane transportGO:00986602340.011
peptide transportGO:00158331330.011
forebrain developmentGO:00309003020.011
cellular ion homeostasisGO:00068731650.011
organic anion transportGO:00157111370.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
Human
blood circulationGO:00080151950.011
carbohydrate homeostasisGO:00335001280.011
immune response regulating cell surface receptor signaling pathwayGO:0002768800.011
cell killingGO:0001906670.011
transmission of nerve impulseGO:0019226760.011
regulation of leukocyte proliferationGO:00706631210.010
regulation of vesicle mediated transportGO:00606271390.010
purine ribonucleoside monophosphate metabolic processGO:0009167800.010
interleukin 8 productionGO:003263740.010
protein localization to nucleusGO:00345041210.010
regulation of cytoplasmic transportGO:19036491120.010
b cell differentiationGO:0030183780.010
purine nucleoside monophosphate metabolic processGO:0009126810.010
metal ion homeostasisGO:00550651890.010
neuron apoptotic processGO:00514021420.010
amide transportGO:00428861380.010
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.010
extracellular structure organizationGO:00430621480.010
regulation of system processGO:00440572000.010
negative regulation of protein phosphorylationGO:00019331260.010
morphogenesis of a branching epitheliumGO:00611381930.010
regulation of intracellular transportGO:00323861590.010
organelle fissionGO:00482851700.010
t cell proliferationGO:00420981200.010
monocarboxylic acid metabolic processGO:00327871910.010
lateral inhibitionGO:004633110.010
cellular response to organic cyclic compoundGO:0071407870.010
methylationGO:00322591340.010

Trim5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.020
cancerDOID:16200.014
disease of cellular proliferationDOID:1456600.014
organ system cancerDOID:005068600.014
nervous system diseaseDOID:86300.013
disease of anatomical entityDOID:700.013
connective tissue diseaseDOID:6500.013
bone diseaseDOID:008000100.013
musculoskeletal system diseaseDOID:1700.013
immune system diseaseDOID:291400.012
sensory system diseaseDOID:005015500.011
inherited metabolic disorderDOID:65500.010