Mus musculus

0 known processes

Spint2

serine protease inhibitor, Kunitz type 2

(Aliases: C76321,HAI-2,AL024025)

Spint2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550854120.064
cellular amino acid metabolic processGO:00065201030.054
cellular response to lipopolysaccharideGO:0071222770.053
leukocyte differentiationGO:00025213420.048
regulation of neuron differentiationGO:00456642810.047
cellular response to lipidGO:00713961450.044
cation transmembrane transportGO:00986552660.044
negative regulation of protein metabolic processGO:00512482820.043
cell adhesionGO:00071553290.043
positive regulation of nervous system developmentGO:00519622210.041
regulation of kinase activityGO:00435492490.041
mapk cascadeGO:00001652810.041
skeletal system developmentGO:00015013560.039
inorganic cation transmembrane transportGO:00986622070.039
regulation of cellular amino acid metabolic processGO:000652150.039
muscle tissue developmentGO:00605373080.037
cellular ketone metabolic processGO:0042180840.037
amine metabolic processGO:0009308450.037
single organism cell adhesionGO:00986021560.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
nucleobase containing small molecule metabolic processGO:00550863520.036
membrane organizationGO:00610242450.035
endomembrane system organizationGO:00102561470.035
posttranscriptional regulation of gene expressionGO:00106081550.034
macromolecule catabolic processGO:00090572810.034
positive regulation of neuron projection developmentGO:0010976790.033
methylationGO:00322591340.033
cell junction organizationGO:0034330770.033
positive regulation of programmed cell deathGO:00430682180.033
regulation of cell projection organizationGO:00313442060.033
cellular nitrogen compound catabolic processGO:00442702800.032
germ cell developmentGO:00072811850.032
oxidation reduction processGO:00551143420.032
morphogenesis of embryonic epitheliumGO:00163311590.031
regulation of cellular ketone metabolic processGO:0010565660.031
apoptotic signaling pathwayGO:00971903060.031
regulation of neuron projection developmentGO:00109751690.030
regulation of membrane potentialGO:00423911920.030
protein maturationGO:00516041760.030
ribose phosphate metabolic processGO:00196932910.030
protein catabolic processGO:00301632210.029
sensory perception of soundGO:0007605970.029
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.028
compound eye developmentGO:004874910.028
response to organic cyclic compoundGO:00140701980.028
muscle cell differentiationGO:00426922610.028
positive regulation of neuron differentiationGO:00456661410.028
response to lipopolysaccharideGO:00324961280.028
peptidyl amino acid modificationGO:00181933360.028
oocyte anterior posterior axis specificationGO:000731420.028
epithelial cell developmentGO:00020641590.028
negative regulation of phosphate metabolic processGO:00459361840.027
action potentialGO:0001508780.027
cellular modified amino acid metabolic processGO:0006575630.027
ribonucleotide metabolic processGO:00092592910.027
positive regulation of cellular amine metabolic processGO:003324050.027
cellular macromolecule catabolic processGO:00442652060.027
nucleotide metabolic processGO:00091173320.027
protein localization to plasma membraneGO:0072659570.026
regulation of organelle organizationGO:00330432890.026
positive regulation of cell developmentGO:00107202370.026
actin cytoskeleton organizationGO:00300362200.026
negative regulation of cellular protein metabolic processGO:00322692470.026
embryonic epithelial tube formationGO:00018381300.026
macromolecule methylationGO:00434141200.025
positive regulation of protein modification processGO:00314012990.025
gland developmentGO:00487323300.025
organelle assemblyGO:00709251770.025
response to molecule of bacterial originGO:00022371430.025
cell junction maintenanceGO:003433140.025
negative regulation of cell proliferationGO:00082852960.025
sensory perceptionGO:00076002450.024
regulation of protein serine threonine kinase activityGO:00719001570.024
male gamete generationGO:00482322850.024
positive regulation of intracellular transportGO:0032388700.024
ossificationGO:00015032160.024
regulation of proteolysisGO:00301621640.024
regulation of apoptotic signaling pathwayGO:20012331970.023
regulation of defense responseGO:00313472330.023
regulation of hydrolase activityGO:00513362460.023
purine containing compound metabolic processGO:00725213110.023
positive regulation of hydrolase activityGO:00513451480.023
cell cell junction organizationGO:0045216720.023
adherens junction maintenanceGO:003433410.023
response to inorganic substanceGO:0010035960.023
regulation of cellular amine metabolic processGO:0033238200.023
translationGO:0006412930.023
regulation of protein kinase activityGO:00458592320.022
heterocycle catabolic processGO:00467002800.022
reactive oxygen species metabolic processGO:0072593840.022
positive regulation of cell projection organizationGO:0031346950.022
negative regulation of cellular component organizationGO:00511291940.022
developmental growth involved in morphogenesisGO:00605601380.022
purine nucleoside triphosphate catabolic processGO:00091462030.022
regulation of mapk cascadeGO:00434082480.021
oocyte axis specificationGO:000730920.021
regulation of ion transmembrane transportGO:00347651190.021
regulation of cell morphogenesis involved in differentiationGO:00107691510.021
purine ribonucleoside metabolic processGO:00461282410.021
purine nucleoside metabolic processGO:00422782410.021
negative regulation of phosphorylationGO:00423261660.021
regulation of anatomical structure sizeGO:00900661780.021
blood vessel morphogenesisGO:00485142850.021
t cell differentiationGO:00302171740.021
multicellular organismal signalingGO:0035637910.020
regulation of transmembrane transportGO:00347621280.020
t cell activationGO:00421102890.020
negative regulation of cell developmentGO:00107211690.020
positive regulation of cell deathGO:00109422240.020
lymphocyte proliferationGO:00466511640.020
protein localization to membraneGO:00726571080.020
leukocyte proliferationGO:00706611720.020
dna metabolic processGO:00062593030.020
epithelial tube morphogenesisGO:00605623030.020
intracellular mrna localizationGO:000829840.020
pole plasm assemblyGO:000731520.020
nitrogen compound transportGO:00717052710.020
aromatic compound catabolic processGO:00194392860.020
response to organonitrogen compoundGO:00102432460.020
neural precursor cell proliferationGO:00613511210.020
striated muscle tissue developmentGO:00147062930.020
ion transmembrane transportGO:00342203610.019
regulation of cell cycleGO:00517262810.019
myeloid leukocyte differentiationGO:00025731190.019
lymphocyte differentiationGO:00300982420.019
mitotic cell cycleGO:00002781950.019
oocyte constructionGO:000730820.019
purine nucleotide metabolic processGO:00061633020.019
gene silencing by mirnaGO:0035195100.019
ribonucleoside metabolic processGO:00091192450.019
inorganic ion transmembrane transportGO:00986602340.019
spermatogenesisGO:00072832840.019
protein targetingGO:00066051430.019
positive regulation of protein phosphorylationGO:00019342420.019
stem cell developmentGO:00488642190.018
homeostasis of number of cellsGO:00488722100.018
protein methylationGO:0006479810.018
cofactor metabolic processGO:0051186800.018
regulation of peptidase activityGO:0052547960.018
plasma membrane organizationGO:0007009900.018
regulation of cellular response to stressGO:00801351590.018
glycosyl compound metabolic processGO:19016572460.018
cellular response to molecule of bacterial originGO:0071219830.018
nucleocytoplasmic transportGO:00069131390.018
carbohydrate metabolic processGO:00059752300.018
cellular response to dna damage stimulusGO:00069742070.018
nuclear transportGO:00511691390.018
negative regulation of molecular functionGO:00440922580.018
negative regulation of intracellular signal transductionGO:19025321670.018
protein alkylationGO:0008213810.018
intrinsic apoptotic signaling pathwayGO:00971931320.018
regulation of cell adhesionGO:00301551540.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.018
small gtpase mediated signal transductionGO:0007264970.017
intracellular protein transportGO:00068862040.017
protein localization to organelleGO:00333651850.017
nucleoside phosphate metabolic processGO:00067533380.017
tube formationGO:00351481400.017
positive regulation of apoptotic processGO:00430652170.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.017
developmental maturationGO:00217001930.017
locomotory behaviorGO:00076261950.017
spermatid developmentGO:00072861080.017
camera type eye developmentGO:00430102660.017
stem cell differentiationGO:00488632680.017
negative regulation of transferase activityGO:0051348850.017
neural tube formationGO:00018411080.017
regulation of cell motilityGO:20001452360.017
neuron deathGO:00709971540.017
sulfur compound metabolic processGO:00067901000.017
regulation of leukocyte differentiationGO:19021051590.017
oligopeptide transmembrane transportGO:003567240.016
sensory perception of mechanical stimulusGO:00509541070.016
organic anion transportGO:00157111370.016
regulation of t cell activationGO:00508631700.016
fertilizationGO:00095661270.016
purine ribonucleotide catabolic processGO:00091542080.016
purine ribonucleoside catabolic processGO:00461302050.016
organic cyclic compound catabolic processGO:19013612950.016
cellular amine metabolic processGO:0044106440.016
cation transportGO:00068123990.016
nucleoside phosphate catabolic processGO:19012922220.016
organelle localizationGO:00516401790.016
divalent inorganic cation transportGO:00725111780.016
neural tube developmentGO:00219151600.016
establishment of protein localization to plasma membraneGO:0090002340.016
regulation of cell activationGO:00508652890.016
regulation of body fluid levelsGO:00508781620.016
ribonucleotide catabolic processGO:00092612080.016
negative regulation of nervous system developmentGO:00519611560.016
regulation of lymphocyte activationGO:00512492400.016
symbiosis encompassing mutualism through parasitismGO:0044403830.015
nucleoside catabolic processGO:00091642060.015
myd88 independent toll like receptor signaling pathwayGO:000275630.015
cytoplasmic transportGO:00164822340.015
single organism nuclear importGO:1902593950.015
regulation of cd8 positive alpha beta t cell proliferationGO:200056410.015
transmission of nerve impulseGO:0019226760.015
glycosyl compound catabolic processGO:19016582060.015
regionalizationGO:00030023370.015
forebrain developmentGO:00309003020.015
regulation of intracellular transportGO:00323861590.015
regulation of multi organism processGO:00439001110.015
cell junction assemblyGO:0034329520.015
negative regulation of organelle organizationGO:0010639900.015
cell type specific apoptotic processGO:00972852680.015
positive regulation of mapk cascadeGO:00434101700.015
organic hydroxy compound metabolic processGO:19016152030.015
skeletal muscle organ developmentGO:00605381630.015
regulation of cell migrationGO:00303342190.015
negative regulation of immune system processGO:00026832090.015
regulation of endopeptidase activityGO:0052548890.015
regulation of ion transportGO:00432692150.015
negative regulation of protein phosphorylationGO:00019331260.015
regulation of homeostatic processGO:00328441820.015
myeloid cell differentiationGO:00300992330.015
establishment of organelle localizationGO:00516561220.015
chromatin organizationGO:00063252060.015
microtubule based processGO:00070172360.014
protein localization to nucleusGO:00345041210.014
protein processingGO:00164851630.014
nucleotide catabolic processGO:00091662170.014
mitochondrion organizationGO:00070051340.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
purine ribonucleoside triphosphate metabolic processGO:00092052200.014
rna interferenceGO:001624620.014
ear developmentGO:00435832000.014
circulatory system processGO:00030131970.014
blastocyst developmentGO:0001824800.014
neuron apoptotic processGO:00514021420.014
extrinsic apoptotic signaling pathwayGO:00971911260.014
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.014
negative regulation of kinase activityGO:0033673810.014
cellular chemical homeostasisGO:00550822150.014
hematopoietic progenitor cell differentiationGO:00022441430.014
embryonic placenta developmentGO:0001892980.014
establishment of protein localization to membraneGO:0090150540.014
protein modification by small protein conjugation or removalGO:00706472070.014
regulation of epithelial cell proliferationGO:00506781410.014
respiratory system developmentGO:00605411900.014
response to acid chemicalGO:00011011110.014
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.014
negative regulation of phosphorus metabolic processGO:00105631840.014
purine containing compound catabolic processGO:00725232130.014
single organismal cell cell adhesionGO:00163371310.013
proteolysis involved in cellular protein catabolic processGO:00516031470.013
epithelial tube formationGO:00721751300.013
cellular response to biotic stimulusGO:0071216920.013
heart morphogenesisGO:00030071780.013
modification dependent protein catabolic processGO:00199411330.013
defense response to other organismGO:00985421970.013
endocrine system developmentGO:0035270980.013
interspecies interaction between organismsGO:0044419830.013
stem cell proliferationGO:00720891170.013
angiogenesisGO:00015252010.013
blood circulationGO:00080151950.013
cellular alcohol biosynthetic processGO:004410830.013
regulation of cellular component biogenesisGO:00440871810.013
stem cell maintenanceGO:00198271300.013
regulation of lymphocyte differentiationGO:00456191070.013
multicellular organismal homeostasisGO:00488711640.013
cell fate commitmentGO:00451652100.013
maternal determination of anterior posterior axis embryoGO:000835820.013
regulation of protein localizationGO:00328802310.013
cellular response to growth factor stimulusGO:00713631970.013
purine nucleotide catabolic processGO:00061952110.013
innate immune responseGO:00450871570.013
monocarboxylic acid metabolic processGO:00327871910.013
regulation of intracellular protein transportGO:0033157820.013
single fertilizationGO:0007338820.013
nucleoside triphosphate catabolic processGO:00091432050.013
morphogenesis of a branching structureGO:00017632030.013
zymogen activationGO:0031638410.013
ear morphogenesisGO:00424711180.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
epithelial cell proliferationGO:00506731740.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
bmp signaling pathwayGO:0030509930.013
cellular lipid metabolic processGO:00442553230.012
alpha amino acid metabolic processGO:1901605590.012
regulation of translationGO:0006417710.012
organelle fissionGO:00482851700.012
regulation of actin filament based processGO:0032970990.012
asymmetric stem cell divisionGO:009872230.012
formation of organ boundaryGO:001016010.012
nucleoside metabolic processGO:00091162460.012
positive regulation of transferase activityGO:00513471670.012
leukocyte activation involved in immune responseGO:00023661260.012
cell maturationGO:00484691270.012
lateral inhibitionGO:004633110.012
organophosphate catabolic processGO:00464342320.012
coenzyme metabolic processGO:0006732520.012
leukocyte mediated immunityGO:00024431740.012
carbohydrate derivative catabolic processGO:19011362310.012
golgi vesicle transportGO:0048193300.012
anion transmembrane transportGO:0098656710.012
purine nucleoside triphosphate metabolic processGO:00091442260.012
gonad developmentGO:00084061410.012
regulation of system processGO:00440572000.012
hexose metabolic processGO:0019318980.012
interleukin 8 productionGO:003263740.012
divalent metal ion transportGO:00708381720.012
dna repairGO:00062811070.012
ventricular cardiac muscle cell action potentialGO:008600540.012
protein importGO:00170381010.012
retina development in camera type eyeGO:00600411190.012
regulation of cell cycle processGO:00105641600.012
immune effector processGO:00022523210.012
placenta developmentGO:00018901400.011
positive regulation of growthGO:00459271040.011
cellular response to inorganic substanceGO:0071241370.011
response to peptideGO:19016521360.011
regulation of cytoplasmic transportGO:19036491120.011
connective tissue developmentGO:00614481790.011
cell cell junction maintenanceGO:004521730.011
cellular protein complex assemblyGO:00436231160.011
regulation of lymphocyte proliferationGO:00506701170.011
calcium ion transportGO:00068161590.011
positive regulation of protein transportGO:0051222930.011
regulation of cysteine type endopeptidase activityGO:2000116650.011
cellular alcohol metabolic processGO:004410730.011
negative regulation of mapk cascadeGO:0043409650.011
regulation of neuron deathGO:19012141340.011
cell recognitionGO:0008037830.011
small molecule biosynthetic processGO:00442831320.011
columnar cuboidal epithelial cell differentiationGO:0002065820.011
wound healingGO:00420601570.011
cytokine mediated signaling pathwayGO:00192211150.011
lymphocyte mediated immunityGO:00024491390.011
regulation of purine nucleotide metabolic processGO:19005421690.011
cell activation involved in immune responseGO:00022631260.011
neuron migrationGO:00017641220.011
heart contractionGO:0060047930.011
synapse organizationGO:00508081250.011
striated muscle cell developmentGO:00550021250.011
regulation of leukocyte proliferationGO:00706631210.011
regulation of interleukin 8 productionGO:003267730.011
negative regulation of growthGO:0045926990.011
response to oxidative stressGO:00069791230.011
regulation of organ morphogenesisGO:20000271440.011
cellular response to acid chemicalGO:0071229680.011
regulation of response to woundingGO:19030341890.011
establishment or maintenance of cell polarityGO:0007163860.011
cellular response to organonitrogen compoundGO:00714171450.011
regulation of glucose metabolic processGO:0010906600.011
fat cell differentiationGO:00454441600.011
response to nutrient levelsGO:00316671090.011
fatty acid metabolic processGO:00066311210.011
purine ribonucleotide metabolic processGO:00091502900.011
regulation of map kinase activityGO:00434051200.011
organic hydroxy compound transportGO:0015850930.011
regulation of protein catabolic processGO:00421761080.011
ras protein signal transductionGO:0007265770.011
ribonucleoside triphosphate catabolic processGO:00092031990.011
regulation of wnt signaling pathwayGO:00301111230.011
cell divisionGO:00513011200.011
ubiquitin dependent protein catabolic processGO:00065111290.011
establishment of protein localization to organelleGO:00725941180.010
carbohydrate homeostasisGO:00335001280.010
morphogenesis of a branching epitheliumGO:00611381930.010
alpha beta t cell activationGO:0046631910.010
cellular response to cytokine stimulusGO:00713451890.010
regulation of transferase activityGO:00513382630.010
regulation of cellular component sizeGO:00325351210.010
embryonic skeletal system developmentGO:00487061200.010
amide transportGO:00428861380.010
muscle cell developmentGO:00550011330.010
cardiac chamber morphogenesisGO:0003206930.010
cognitionGO:00508901490.010
regulation of establishment of protein localizationGO:00702011810.010
cardiac muscle contractionGO:0060048320.010
cellularizationGO:000734910.010
regulation of reactive oxygen species metabolic processGO:2000377400.010
nucleoside triphosphate metabolic processGO:00091412300.010
regulation of mitotic cell cycleGO:00073461260.010
nuclear importGO:0051170950.010
regulation of nucleoside metabolic processGO:00091181300.010
monosaccharide metabolic processGO:00059961060.010
nucleoside monophosphate metabolic processGO:0009123850.010
positive regulation of nucleotide metabolic processGO:00459811140.010
histone modificationGO:00165701590.010
developmental cell growthGO:0048588840.010
response to testosteroneGO:003357430.010
regulation of cell cell adhesion mediated by cadherinGO:200004720.010
negative regulation of protein modification processGO:00314001630.010
localization within membraneGO:005166840.010
sensory system developmentGO:004888030.010
lymphocyte activation involved in immune responseGO:0002285930.010
positive regulation of cell activationGO:00508671580.010

Spint2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.044
organ system cancerDOID:005068600.044
cancerDOID:16200.044
nervous system diseaseDOID:86300.028
disease of anatomical entityDOID:700.028
gastrointestinal system cancerDOID:311900.022
thoracic cancerDOID:509300.020
sensory system diseaseDOID:005015500.018
musculoskeletal system diseaseDOID:1700.016
reproductive organ cancerDOID:19300.013
male reproductive organ cancerDOID:385600.013
physical disorderDOID:008001500.012
inherited metabolic disorderDOID:65500.011
disease of metabolismDOID:001466700.011
breast cancerDOID:161200.011
bone diseaseDOID:008000100.011
connective tissue diseaseDOID:6500.011
prostate cancerDOID:1028300.010