IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Stag3

stromal antigen 3

(Aliases: SA-2)

Entrez: 50878
Ensembl: ENSMUSG00000036928
UniProtKB: O70576

Process Predictions
Disease Predictions

Stag3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
synapsis	GO:0007129	34	0.799
male meiosis	GO:0007140	37	0.781
chromosome organization involved in meiosis	GO:0070192	39	0.692
male meiosis i	GO:0007141	16	0.563
meiosis i	GO:0007127	60	0.561
spermatogenesis	GO:0007283	284	0.397
meiotic nuclear division	GO:0007126	115	0.375
dna metabolic process	GO:0006259	303	0.340
meiotic cell cycle process	GO:1903046	77	0.336
nuclear division	GO:0000280	158	0.322
male gamete generation	GO:0048232	285	0.284
dna recombination	GO:0006310	92	0.267
meiotic cell cycle	GO:0051321	122	0.249
organelle fission	GO:0048285	170	0.222
spermatid development	GO:0007286	108	0.182
anion transport	GO:0006820	177	0.158
dna repair	GO:0006281	107	0.147
cellular response to dna damage stimulus	GO:0006974	207	0.110
fertilization	GO:0009566	127	0.094
ion transmembrane transport	GO:0034220	361	0.090
sperm motility	GO:0030317	47	0.083
germ cell development	GO:0007281	185	0.071
carboxylic acid transport	GO:0046942	100	0.070
homeostasis of number of cells	GO:0048872	210	0.070
microtubule based process	GO:0007017	236	0.068
double strand break repair via homologous recombination	GO:0000724	21	0.066
spermatid differentiation	GO:0048515	115	0.062
transmembrane transport	GO:0055085	412	0.061
immune effector process	GO:0002252	321	0.060
mitotic cell cycle process	GO:1903047	159	0.057
recombinational repair	GO:0000725	21	0.056
multicellular organismal signaling	GO:0035637	91	0.049
sensory perception	GO:0007600	245	0.048
anion transmembrane transport	GO:0098656	71	0.047
regulation of organelle organization	GO:0033043	289	0.047
multicellular organismal homeostasis	GO:0048871	164	0.044
anatomical structure homeostasis	GO:0060249	145	0.044
organic anion transport	GO:0015711	137	0.043
organelle localization	GO:0051640	179	0.040
regulation of cell cycle process	GO:0010564	160	0.040
macromolecule catabolic process	GO:0009057	281	0.039
macromolecule methylation	GO:0043414	120	0.038
response to radiation	GO:0009314	165	0.038
oocyte axis specification	GO:0007309	2	0.037
chromosome segregation	GO:0007059	48	0.037
positive regulation of programmed cell death	GO:0043068	218	0.036
helper t cell chemotaxis	GO:0035704	1	0.034
cell maturation	GO:0048469	127	0.033	Fly
tissue homeostasis	GO:0001894	115	0.033
protein catabolic process	GO:0030163	221	0.032
double strand break repair	GO:0006302	48	0.031
methylation	GO:0032259	134	0.029
oxidation reduction process	GO:0055114	342	0.029
organelle assembly	GO:0070925	177	0.028
nucleobase containing small molecule metabolic process	GO:0055086	352	0.028
cellular macromolecule catabolic process	GO:0044265	206	0.028
mitotic chromosome condensation	GO:0007076	1	0.028
response to acid chemical	GO:0001101	111	0.027
gland development	GO:0048732	330	0.027
cation transport	GO:0006812	399	0.027
leukocyte homeostasis	GO:0001776	79	0.026
pole plasm assembly	GO:0007315	2	0.026
cell adhesion	GO:0007155	329	0.026
chromatin organization	GO:0006325	206	0.026
dna conformation change	GO:0071103	37	0.026
multicellular organism growth	GO:0035264	161	0.026
chemotaxis	GO:0006935	247	0.026
neuroblast differentiation	GO:0014016	2	0.026
protein processing	GO:0016485	163	0.025
regulation of secretion	GO:0051046	274	0.025
carbohydrate derivative biosynthetic process	GO:1901137	183	0.025
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.024
positive regulation of cell cycle	GO:0045787	92	0.024
rna splicing	GO:0008380	54	0.024
regulation of multi organism process	GO:0043900	111	0.024
stem cell maintenance	GO:0019827	130	0.024	Mouse
glycoprotein metabolic process	GO:0009100	116	0.024
hindbrain development	GO:0030902	128	0.024
cation transmembrane transport	GO:0098655	266	0.024
positive regulation of cell death	GO:0010942	224	0.024
neuron projection guidance	GO:0097485	141	0.023
macula densa development	GO:0072024	1	0.023
myeloid cell differentiation	GO:0030099	233	0.023
oocyte anterior posterior axis specification	GO:0007314	2	0.023
purine ribonucleoside monophosphate metabolic process	GO:0009167	80	0.023
skeletal system development	GO:0001501	356	0.023
membrane organization	GO:0061024	245	0.023
nucleotide metabolic process	GO:0009117	332	0.023
aromatic compound catabolic process	GO:0019439	286	0.023
purine nucleotide metabolic process	GO:0006163	302	0.023
inorganic cation transmembrane transport	GO:0098662	207	0.023
heterocycle catabolic process	GO:0046700	280	0.022
posttranscriptional regulation of gene expression	GO:0010608	155	0.022
rna processing	GO:0006396	105	0.022
cellularization	GO:0007349	1	0.022
exocytosis	GO:0006887	121	0.022
purine ribonucleotide metabolic process	GO:0009150	290	0.022
myeloid cell homeostasis	GO:0002262	114	0.022
ribose phosphate biosynthetic process	GO:0046390	59	0.022
regulation of cellular ketone metabolic process	GO:0010565	66	0.022
protein maturation	GO:0051604	176	0.021
retinoid metabolic process	GO:0001523	24	0.021
purine containing compound metabolic process	GO:0072521	311	0.021
positive regulation of hydrolase activity	GO:0051345	148	0.021
kidney development	GO:0001822	213	0.021
cilium morphogenesis	GO:0060271	102	0.021
regulation of homeostatic process	GO:0032844	182	0.020
microtubule based movement	GO:0007018	84	0.020
ribonucleotide metabolic process	GO:0009259	291	0.020
organic acid transport	GO:0015849	101	0.020
nucleoside phosphate metabolic process	GO:0006753	338	0.020
mitotic cell cycle	GO:0000278	195	0.020
atp metabolic process	GO:0046034	75	0.020
positive regulation of protein modification process	GO:0031401	299	0.020
mitotic sister chromatid segregation	GO:0000070	14	0.020
cellular nitrogen compound catabolic process	GO:0044270	280	0.020
lung development	GO:0030324	164	0.020
activation of immune response	GO:0002253	138	0.020
rhodopsin mediated signaling pathway	GO:0016056	4	0.020
protein citrullination	GO:0018101	2	0.020
skeletal system morphogenesis	GO:0048705	203	0.020
ribose phosphate metabolic process	GO:0019693	291	0.020
inorganic anion transport	GO:0015698	43	0.019
cofactor transport	GO:0051181	4	0.019
cell fate commitment	GO:0045165	210	0.019
leukocyte differentiation	GO:0002521	342	0.019
respiratory tube development	GO:0030323	167	0.019
forebrain development	GO:0030900	302	0.019
blood coagulation	GO:0007596	76	0.019
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.019
gonad development	GO:0008406	141	0.019
visual perception	GO:0007601	52	0.019
regulation of leukocyte apoptotic process	GO:2000106	56	0.019
establishment of organelle localization	GO:0051656	122	0.019
lymphocyte mediated immunity	GO:0002449	139	0.018
cytoplasmic transport	GO:0016482	234	0.018
oocyte construction	GO:0007308	2	0.018
lymphocyte apoptotic process	GO:0070227	54	0.018
reactive oxygen species metabolic process	GO:0072593	84	0.018
urogenital system development	GO:0001655	261	0.018
sensory perception of light stimulus	GO:0050953	54	0.018
lipid transport	GO:0006869	98	0.018
signal transduction involved in dna damage checkpoint	GO:0072422	3	0.018
male gonad development	GO:0008584	88	0.018
intracellular mrna localization	GO:0008298	4	0.018
compound eye development	GO:0048749	1	0.018
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.018
dna modification	GO:0006304	50	0.018
stem cell differentiation	GO:0048863	268	0.017	Mouse
regulation of body fluid levels	GO:0050878	162	0.017
positive regulation of apoptotic process	GO:0043065	217	0.017
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.017
regulation of myeloid cell differentiation	GO:0045637	96	0.017
nitrogen compound transport	GO:0071705	271	0.017
regulation of cell cycle	GO:0051726	281	0.017
inflammatory response	GO:0006954	244	0.017
regulation of mitotic cell cycle	GO:0007346	126	0.017
translation	GO:0006412	93	0.017
regulation of secretion by cell	GO:1903530	249	0.017
embryonic organ morphogenesis	GO:0048562	276	0.017
regulation of protein kinase activity	GO:0045859	232	0.017
regulation of isoprenoid metabolic process	GO:0019747	1	0.017
response to growth factor	GO:0070848	198	0.017
regulation of translation	GO:0006417	71	0.017
regulation of cellular component biogenesis	GO:0044087	181	0.017
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.016
cell recognition	GO:0008037	83	0.016
regulation of nuclear division	GO:0051783	56	0.016
thick ascending limb development	GO:0072023	2	0.016
metal ion homeostasis	GO:0055065	189	0.016
purine ribonucleoside metabolic process	GO:0046128	241	0.016
muscle tissue development	GO:0060537	308	0.016
regulation of protein binding	GO:0043393	60	0.016
positive regulation of protein kinase activity	GO:0045860	144	0.016
cellular homeostasis	GO:0019725	240	0.016
negative regulation of calcium ion dependent exocytosis	GO:0045955	3	0.016
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.016
protein modification by small protein conjugation	GO:0032446	187	0.016
selenium compound metabolic process	GO:0001887	3	0.016
regulation of cell adhesion	GO:0030155	154	0.016
cellular amino acid metabolic process	GO:0006520	103	0.016
leukocyte apoptotic process	GO:0071887	71	0.015
nucleoside metabolic process	GO:0009116	246	0.015
regulation of ion transmembrane transport	GO:0034765	119	0.015
renal system development	GO:0072001	225	0.015
development of primary sexual characteristics	GO:0045137	143	0.015
mrna metabolic process	GO:0016071	84	0.015
reactive oxygen species biosynthetic process	GO:1903409	8	0.015
regulation of monocyte chemotaxis	GO:0090025	3	0.015
regulation of asymmetric cell division	GO:0009786	4	0.015
positive regulation of proteolysis	GO:0045862	85	0.015
cellular component assembly involved in morphogenesis	GO:0010927	139	0.015
nucleoside triphosphate metabolic process	GO:0009141	230	0.015
cell type specific apoptotic process	GO:0097285	268	0.015
leukocyte proliferation	GO:0070661	172	0.015
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.015
asymmetric stem cell division	GO:0098722	3	0.015
microtubule cytoskeleton organization	GO:0000226	157	0.015
nucleotide biosynthetic process	GO:0009165	78	0.015
oocyte maturation	GO:0001556	18	0.015
negative regulation of cell cycle	GO:0045786	123	0.015
striated muscle adaptation	GO:0014888	26	0.015
positive regulation of leukocyte apoptotic process	GO:2000108	21	0.015
regulation of heart induction by regulation of canonical wnt signaling pathway	GO:0090081	2	0.014
developmental maturation	GO:0021700	193	0.014	Fly
somatotropin secreting cell differentiation	GO:0060126	4	0.014
mast cell proliferation	GO:0070662	4	0.014
t cell proliferation	GO:0042098	120	0.014
type b pancreatic cell proliferation	GO:0044342	10	0.014
fucosylation	GO:0036065	9	0.014
cellular response to biotic stimulus	GO:0071216	92	0.014
hemostasis	GO:0007599	78	0.014
nucleocytoplasmic transport	GO:0006913	139	0.014
negative regulation of cellular protein metabolic process	GO:0032269	247	0.014
cell cycle checkpoint	GO:0000075	47	0.014
ovarian follicle development	GO:0001541	40	0.014
sperm egg recognition	GO:0035036	37	0.014
dna methylation	GO:0006306	43	0.014
negative regulation of protein metabolic process	GO:0051248	282	0.014
mrna processing	GO:0006397	63	0.014
liver development	GO:0001889	66	0.014
regulation of lymphocyte apoptotic process	GO:0070228	41	0.014
myeloid leukocyte mediated immunity	GO:0002444	42	0.014
regulation of binding	GO:0051098	111	0.014
positive regulation of fibronectin dependent thymocyte migration	GO:2000415	1	0.014
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.014
myeloid leukocyte differentiation	GO:0002573	119	0.014
regulation of ketone biosynthetic process	GO:0010566	2	0.014
regulation of mast cell proliferation	GO:0070666	4	0.014
vitamin a metabolic process	GO:0006776	2	0.014
determination of left right asymmetry in nervous system	GO:0035545	1	0.013
regulation of transposition	GO:0010528	2	0.013
proprioception	GO:0019230	4	0.013
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.013
glycosyl compound metabolic process	GO:1901657	246	0.013
transmission of nerve impulse	GO:0019226	76	0.013
purine containing compound biosynthetic process	GO:0072522	70	0.013
response to light stimulus	GO:0009416	135	0.013
reciprocal meiotic recombination	GO:0007131	16	0.013
organonitrogen compound biosynthetic process	GO:1901566	192	0.013
growth involved in heart morphogenesis	GO:0003241	4	0.013
epithelial tube morphogenesis	GO:0060562	303	0.013
calcium ion transmembrane transport	GO:0070588	85	0.013
chromatin modification	GO:0016568	187	0.013
regulation of system process	GO:0044057	200	0.013
microtubule based transport	GO:0010970	50	0.013
endomembrane system organization	GO:0010256	147	0.013
cellular response to acid chemical	GO:0071229	68	0.013
negative regulation of transposition	GO:0010529	2	0.013
cell substrate adhesion	GO:0031589	130	0.013
monocarboxylic acid transport	GO:0015718	44	0.013
regulation of protein catabolic process	GO:0042176	108	0.013
regulation of protein serine threonine kinase activity	GO:0071900	157	0.013
ribonucleoside metabolic process	GO:0009119	245	0.013
purine nucleoside monophosphate catabolic process	GO:0009128	58	0.013
lymphocyte homeostasis	GO:0002260	64	0.013
osteoclast differentiation	GO:0030316	62	0.013
platelet activation	GO:0030168	40	0.013
mitotic nuclear division	GO:0007067	48	0.013
reciprocal dna recombination	GO:0035825	16	0.013
rna interference	GO:0016246	2	0.013
negative regulation of cell size	GO:0045792	3	0.013
dna alkylation	GO:0006305	43	0.012
negative regulation of cytoskeleton organization	GO:0051494	36	0.012
phototransduction	GO:0007602	17	0.012
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.012
negative regulation of intracellular signal transduction	GO:1902532	167	0.012
eosinophil migration	GO:0072677	3	0.012
leukocyte mediated immunity	GO:0002443	174	0.012
phospholipid transfer to membrane	GO:0006649	2	0.012
respiratory system development	GO:0060541	190	0.012
regulation of cell shape	GO:0008360	39	0.012
epithalamus development	GO:0021538	2	0.012
activation of adenylate cyclase activity	GO:0007190	4	0.012
t helper 17 cell chemotaxis	GO:0035705	1	0.012
cellular response to growth factor stimulus	GO:0071363	197	0.012
regulation of cell projection organization	GO:0031344	206	0.012
hormone secretion	GO:0046879	128	0.012
regulation of lipid transport	GO:0032368	36	0.012
inorganic ion transmembrane transport	GO:0098660	234	0.012
cell division	GO:0051301	120	0.012
nucleoside monophosphate metabolic process	GO:0009123	85	0.012
somatotropin secreting cell development	GO:0060133	2	0.012
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	43	0.012
mitotic cell cycle checkpoint	GO:0007093	31	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	61	0.012
regulation of protein transport	GO:0051223	163	0.012
ribonucleoside monophosphate catabolic process	GO:0009158	57	0.012
t cell activation	GO:0042110	289	0.012
positive regulation of immune effector process	GO:0002699	107	0.012
leukocyte activation involved in immune response	GO:0002366	126	0.012
rhombomere 5 development	GO:0021571	4	0.012
regulation of hydrolase activity	GO:0051336	246	0.012
camera type eye development	GO:0043010	266	0.012
purine ribonucleotide biosynthetic process	GO:0009152	59	0.012
neuronal action potential	GO:0019228	54	0.011
reactive nitrogen species metabolic process	GO:2001057	0	0.011
oogenesis	GO:0048477	56	0.011
regulation of intracellular transport	GO:0032386	159	0.011
leukocyte migration	GO:0050900	124	0.011
regulation of apoptotic signaling pathway	GO:2001233	197	0.011
steroid metabolic process	GO:0008202	119	0.011
genetic imprinting	GO:0071514	27	0.011
neuroblast fate determination	GO:0007400	1	0.011
cilium assembly	GO:0042384	81	0.011
lipid localization	GO:0010876	126	0.011
regulation of membrane potential	GO:0042391	192	0.011
apoptotic signaling pathway	GO:0097190	306	0.011
retina homeostasis	GO:0001895	23	0.011
atp catabolic process	GO:0006200	55	0.011
mesonephric epithelium development	GO:0072163	94	0.011
negative regulation of cell proliferation	GO:0008285	296	0.011
vestibular nucleus development	GO:0021750	2	0.011
cerebral cortex development	GO:0021987	86	0.011
alpha amino acid metabolic process	GO:1901605	59	0.011
negative regulation of cell activation	GO:0050866	111	0.011
inner cell mass cell fate commitment	GO:0001827	2	0.011
inorganic anion transmembrane transport	GO:0098661	29	0.011
response to retinoic acid	GO:0032526	56	0.011
germinal center formation	GO:0002467	16	0.011
negative regulation of cholesterol transport	GO:0032375	4	0.011
interleukin 8 secretion	GO:0072606	3	0.011
positive regulation of transferase activity	GO:0051347	167	0.011
meiosis ii	GO:0007135	7	0.011
female sex differentiation	GO:0046660	84	0.011
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation	GO:2000526	1	0.011
t cell differentiation in thymus	GO:0033077	77	0.011
positive regulation of cellular amine metabolic process	GO:0033240	5	0.011
regulation of transferase activity	GO:0051338	263	0.011
cellular response to hormone stimulus	GO:0032870	150	0.011
blood circulation	GO:0008015	195	0.011
regulation of cellular catabolic process	GO:0031329	242	0.011
negative regulation of phosphate metabolic process	GO:0045936	184	0.011
neurohypophysis development	GO:0021985	2	0.011
regulation of vascular smooth muscle contraction	GO:0003056	1	0.011
endodermal cell fate specification	GO:0001714	4	0.010
nephron epithelium development	GO:0072009	92	0.010
photoreceptor cell maintenance	GO:0045494	19	0.010
hepaticobiliary system development	GO:0061008	67	0.010
regulation of eosinophil migration	GO:2000416	2	0.010
regulation of cell motility	GO:2000145	236	0.010
positive regulation of podosome assembly	GO:0071803	3	0.010
regionalization	GO:0003002	337	0.010
sodium ion transport	GO:0006814	73	0.010
purine ribonucleoside monophosphate catabolic process	GO:0009169	57	0.010
divalent metal ion transport	GO:0070838	172	0.010
regulation of cellular component size	GO:0032535	121	0.010
negative regulation of cell cycle process	GO:0010948	69	0.010
pons development	GO:0021548	13	0.010
locomotory behavior	GO:0007626	195	0.010
cellular metal ion homeostasis	GO:0006875	151	0.010
sister chromatid segregation	GO:0000819	20	0.010
membrane depolarization	GO:0051899	64	0.010
folic acid containing compound metabolic process	GO:0006760	3	0.010
positive regulation of t cell receptor signaling pathway	GO:0050862	4	0.010
regulation of mitosis	GO:0007088	29	0.010
regulation of proteolysis	GO:0030162	164	0.010

Stag3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
musculoskeletal system disease	DOID:17	0.054
disease of anatomical entity	DOID:7	0.054
connective tissue disease	DOID:65	0.047
nervous system disease	DOID:863	0.046
disease of cellular proliferation	DOID:14566	0.045
cancer	DOID:162	0.045
eye and adnexa disease	DOID:1492	0.042
sensory system disease	DOID:0050155	0.042
retinal disease	DOID:5679	0.036
retinal degeneration	DOID:8466	0.036
eye disease	DOID:5614	0.036
organ system cancer	DOID:0050686	0.029
bone disease	DOID:0080001	0.028
thoracic cancer	DOID:5093	0.026
retinitis pigmentosa	DOID:10584	0.025
immune system disease	DOID:2914	0.022
hematopoietic system disease	DOID:74	0.022
hematologic cancer	DOID:2531	0.020
immune system cancer	DOID:0060083	0.020
bone development disease	DOID:0080006	0.011

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