IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Klk1b16

kallikrein 1-related peptidase b16

(Aliases: Klk16,mGk-16)

Ensembl: ENSMUSG00000038968
Entrez: 16615
UniProtKB: P04071

Process Predictions
Disease Predictions

Klk1b16 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
positive regulation of vasoconstriction	GO:0045907	4	0.884	Rat
negative regulation of neuron projection regeneration	GO:0070571	3	0.861	Mouse
left ventricular cardiac muscle tissue morphogenesis	GO:0003220	2	0.851	Mouse
binding of sperm to zona pellucida	GO:0007339	34	0.850	Mouse
cell cell recognition	GO:0009988	44	0.834	Mouse
tissue kallikrein kinin cascade	GO:0002255	1	0.811	Mouse
positive regulation of lipid kinase activity	GO:0090218	11	0.764	Mouse
kinin cascade	GO:0002254	2	0.729	Mouse
peptide metabolic process	GO:0006518	46	0.704	Mouse
vasodilation	GO:0042311	28	0.677	Mouse
bradykinin biosynthetic process	GO:0002936	1	0.677	Mouse
protein activation cascade	GO:0072376	19	0.607	Mouse
sperm egg recognition	GO:0035036	37	0.590	Mouse
action potential	GO:0001508	78	0.512
single fertilization	GO:0007338	82	0.495	Mouse
transmission of nerve impulse	GO:0019226	76	0.478
cellular lipid metabolic process	GO:0044255	323	0.474	Mouse
neuronal action potential	GO:0019228	54	0.434
fertilization	GO:0009566	127	0.425	Mouse
positive regulation of phosphatidylinositol 3 kinase activity	GO:0043552	11	0.400	Mouse
memory	GO:0007613	58	0.393	Mouse
extracellular structure organization	GO:0043062	148	0.388	Mouse
cellular amide metabolic process	GO:0043603	58	0.374	Mouse
regulation of lipid metabolic process	GO:0019216	118	0.373	Mouse
regulation of lipid kinase activity	GO:0043550	14	0.356	Mouse
phospholipid metabolic process	GO:0006644	87	0.345	Mouse
regulation of blood volume by renin angiotensin	GO:0002016	7	0.307	Mouse
keratinocyte proliferation	GO:0043616	21	0.306	Mouse
extracellular matrix organization	GO:0030198	147	0.300	Mouse
muscle tissue development	GO:0060537	308	0.299	Mouse
regulation of blood pressure	GO:0008217	93	0.293	Mouse
striated muscle tissue development	GO:0014706	293	0.289	Mouse
cell recognition	GO:0008037	83	0.280	Mouse
epithelial cell proliferation	GO:0050673	174	0.272	Mouse
protein maturation	GO:0051604	176	0.268	Mouse
positive regulation of blood circulation	GO:1903524	22	0.259	Rat
axon ensheathment	GO:0008366	76	0.248	Mouse
regulation of systemic arterial blood pressure by hormone	GO:0001990	25	0.237	Mouse
positive regulation of kinase activity	GO:0033674	155	0.236	Mouse
regulation of systemic arterial blood pressure mediated by a chemical signal	GO:0003044	33	0.234	Mouse
vasoconstriction	GO:0042310	27	0.231	Rat
regulation of neuron projection regeneration	GO:0070570	7	0.231	Mouse
muscle contraction	GO:0006936	101	0.229	Mouse
small gtpase mediated signal transduction	GO:0007264	97	0.225	Mouse
muscle system process	GO:0003012	141	0.223	Mouse
striated muscle contraction	GO:0006941	45	0.221	Mouse
regulation of blood vessel size	GO:0050880	56	0.221	Mouse Rat
neurological system process involved in regulation of systemic arterial blood pressure	GO:0001976	18	0.206	Mouse
brain renin angiotensin system	GO:0002035	5	0.196	Mouse
positive regulation of lipid metabolic process	GO:0045834	40	0.195	Mouse
positive regulation of transferase activity	GO:0051347	167	0.194	Mouse
myelination	GO:0042552	74	0.189	Mouse
regulation of cell projection organization	GO:0031344	206	0.187	Mouse
multicellular organismal signaling	GO:0035637	91	0.186
cardiac muscle tissue development	GO:0048738	130	0.181	Mouse
cognition	GO:0050890	149	0.180	Mouse
regulation of kinase activity	GO:0043549	249	0.179	Mouse
regulation of response to wounding	GO:1903034	189	0.178	Mouse
regulation of myelination	GO:0031641	20	0.171	Mouse
vascular process in circulatory system	GO:0003018	62	0.149	Mouse Rat
ensheathment of neurons	GO:0007272	76	0.148	Mouse
inflammatory response	GO:0006954	244	0.144	Mouse
negative regulation of neuron projection development	GO:0010977	50	0.142	Mouse
regulation of systemic arterial blood pressure	GO:0003073	61	0.141	Mouse
regulation of cellular response to stress	GO:0080135	159	0.138	Mouse
regulation of neuron differentiation	GO:0045664	281	0.131	Mouse
cellular response to hormone stimulus	GO:0032870	150	0.130
negative regulation of cellular component organization	GO:0051129	194	0.125	Mouse
regulation of neuron projection development	GO:0010975	169	0.120	Mouse
cardiac muscle contraction	GO:0060048	32	0.117	Mouse
heart contraction	GO:0060047	93	0.116	Mouse
zymogen activation	GO:0031638	41	0.116	Mouse
protein processing	GO:0016485	163	0.109	Mouse
circulatory system process	GO:0003013	197	0.109	Mouse Rat
regulation of phosphatidylinositol 3 kinase activity	GO:0043551	14	0.107	Mouse
regulation of tube size	GO:0035150	57	0.104	Mouse Rat
regulation of transferase activity	GO:0051338	263	0.103	Mouse
learning or memory	GO:0007611	148	0.097	Mouse
regulation of vasoconstriction	GO:0019229	14	0.095	Rat
peptide biosynthetic process	GO:0043043	11	0.089	Mouse
regulation of blood circulation	GO:1903522	93	0.089	Rat
negative regulation of response to wounding	GO:1903035	77	0.088	Mouse
response to organic cyclic compound	GO:0014070	198	0.086
negative regulation of cell projection organization	GO:0031345	56	0.082	Mouse
synaptic transmission	GO:0007268	329	0.081	Mouse
regulation of anatomical structure size	GO:0090066	178	0.081	Mouse Rat
purine containing compound metabolic process	GO:0072521	311	0.081
organic hydroxy compound metabolic process	GO:1901615	203	0.078
heart morphogenesis	GO:0003007	178	0.077	Mouse
cation transport	GO:0006812	399	0.074
regulation of membrane potential	GO:0042391	192	0.073
amine metabolic process	GO:0009308	45	0.071
steroid metabolic process	GO:0008202	119	0.070
negative regulation of neuron differentiation	GO:0045665	101	0.070	Mouse
synapse organization	GO:0050808	125	0.068	Mouse
cardiac chamber development	GO:0003205	108	0.067	Mouse
regeneration	GO:0031099	38	0.065	Mouse
ventricular cardiac muscle tissue morphogenesis	GO:0055010	32	0.065	Mouse
cardiac left ventricle morphogenesis	GO:0003214	9	0.064	Mouse
blood circulation	GO:0008015	195	0.064	Mouse Rat
acute inflammatory response	GO:0002526	41	0.063	Mouse
macromolecule catabolic process	GO:0009057	281	0.063	Mouse
amelogenesis	GO:0097186	12	0.062	Mouse
regulation of system process	GO:0044057	200	0.062	Mouse Rat
regulation of systemic arterial blood pressure by renin angiotensin	GO:0003081	20	0.061	Mouse
carbohydrate derivative biosynthetic process	GO:1901137	183	0.059
cardiac muscle tissue morphogenesis	GO:0055008	44	0.058	Mouse
carbohydrate metabolic process	GO:0005975	230	0.055
male gamete generation	GO:0048232	285	0.054
carbohydrate biosynthetic process	GO:0016051	74	0.054
regulation of neurological system process	GO:0031644	22	0.053	Mouse
cardiac ventricle morphogenesis	GO:0003208	50	0.053	Mouse
g protein coupled receptor signaling pathway	GO:0007186	243	0.051
hexose metabolic process	GO:0019318	98	0.051
organonitrogen compound biosynthetic process	GO:1901566	192	0.050	Mouse
cellular chemical homeostasis	GO:0055082	215	0.050
glucose homeostasis	GO:0042593	128	0.050
cellular response to organonitrogen compound	GO:0071417	145	0.050
cardiac chamber morphogenesis	GO:0003206	93	0.048	Mouse
cellular carbohydrate metabolic process	GO:0044262	119	0.047
response to extracellular stimulus	GO:0009991	127	0.046
monocarboxylic acid metabolic process	GO:0032787	191	0.046
cellular homeostasis	GO:0019725	240	0.044
cellular amino acid metabolic process	GO:0006520	103	0.044
rhythmic process	GO:0048511	174	0.043
response to nutrient levels	GO:0031667	109	0.043
cation transmembrane transport	GO:0098655	266	0.043
response to organonitrogen compound	GO:0010243	246	0.043
calcium ion transport	GO:0006816	159	0.043
locomotory behavior	GO:0007626	195	0.043
muscle tissue morphogenesis	GO:0060415	53	0.042	Mouse
carbohydrate derivative catabolic process	GO:1901136	231	0.041
divalent inorganic cation transport	GO:0072511	178	0.041
response to inorganic substance	GO:0010035	96	0.041
cellular response to lipid	GO:0071396	145	0.041
regulation of hormone levels	GO:0010817	211	0.041
generation of precursor metabolites and energy	GO:0006091	103	0.040
circadian rhythm	GO:0007623	114	0.040
spermatogenesis	GO:0007283	284	0.040
nitrogen compound transport	GO:0071705	271	0.038
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.037
lipid biosynthetic process	GO:0008610	179	0.037
transmembrane transport	GO:0055085	412	0.037
digestive system development	GO:0055123	200	0.037
neuron projection regeneration	GO:0031102	14	0.037	Mouse
cellular response to peptide hormone stimulus	GO:0071375	92	0.037
ventricular cardiac muscle tissue development	GO:0003229	38	0.035	Mouse
brown fat cell proliferation	GO:0070342	1	0.035
insulin secretion	GO:0030073	89	0.035
regulation of homeostatic process	GO:0032844	182	0.034
regulation of organelle organization	GO:0033043	289	0.034
multicellular organism growth	GO:0035264	161	0.034
response to steroid hormone	GO:0048545	56	0.033
axon regeneration	GO:0031103	12	0.033	Mouse
cellular response to steroid hormone stimulus	GO:0071383	33	0.033
regulation of carbohydrate metabolic process	GO:0006109	75	0.032
purine ribonucleotide catabolic process	GO:0009154	208	0.032
regulation of secretion by cell	GO:1903530	249	0.032
purine ribonucleotide metabolic process	GO:0009150	290	0.032
regulation of glucose metabolic process	GO:0010906	60	0.031
regulation of cytokine production	GO:0001817	266	0.031
cellular response to monosaccharide stimulus	GO:0071326	47	0.031
regulation of transmembrane transport	GO:0034762	128	0.031
dephosphorylation	GO:0016311	129	0.030
endocrine process	GO:0050886	39	0.030	Mouse
ion transmembrane transport	GO:0034220	361	0.029
regulation of ion transmembrane transport	GO:0034765	119	0.029
negative regulation of cell development	GO:0010721	169	0.029	Mouse
cellular response to peptide	GO:1901653	92	0.029
regulation of body fluid levels	GO:0050878	162	0.029
hormone metabolic process	GO:0042445	86	0.029
purine nucleotide metabolic process	GO:0006163	302	0.029
positive regulation of cytokine production	GO:0001819	174	0.028
regulation of cellular amino acid metabolic process	GO:0006521	5	0.028
negative regulation of neurological system process	GO:0031645	7	0.028	Mouse
amide biosynthetic process	GO:0043604	16	0.027	Mouse
macromolecule methylation	GO:0043414	120	0.027
nucleobase containing small molecule metabolic process	GO:0055086	352	0.027
ribose phosphate metabolic process	GO:0019693	291	0.027
cytokine production	GO:0001816	319	0.027
cellular metal ion homeostasis	GO:0006875	151	0.027
ossification	GO:0001503	216	0.026
regulation of muscle tissue development	GO:1901861	97	0.026
aromatic compound catabolic process	GO:0019439	286	0.026
purine ribonucleoside metabolic process	GO:0046128	241	0.026
calcium ion transmembrane transport	GO:0070588	85	0.026
purine containing compound catabolic process	GO:0072523	213	0.026
regulation of hydrolase activity	GO:0051336	246	0.025
heart process	GO:0003015	94	0.025	Mouse
regulation of eosinophil migration	GO:2000416	2	0.025
protein catabolic process	GO:0030163	221	0.024	Mouse
cellular response to extracellular stimulus	GO:0031668	81	0.024
purine nucleoside metabolic process	GO:0042278	241	0.024
positive regulation of cell development	GO:0010720	237	0.024
acetate ester transport	GO:1901374	2	0.024
nucleoside phosphate catabolic process	GO:1901292	222	0.024
regulation of metal ion transport	GO:0010959	106	0.024
negative regulation of phosphorus metabolic process	GO:0010563	184	0.024
protein modification by small protein conjugation or removal	GO:0070647	207	0.024
regulation of feeding behavior	GO:0060259	3	0.023
mitochondrion organization	GO:0007005	134	0.023
negative regulation of growth	GO:0045926	99	0.023
glycerolipid metabolic process	GO:0046486	122	0.023	Mouse
divalent metal ion transport	GO:0070838	172	0.023
oxidation reduction process	GO:0055114	342	0.023
response to starvation	GO:0042594	65	0.022
regulation of secretion	GO:0051046	274	0.022
inorganic cation transmembrane transport	GO:0098662	207	0.022
glycosyl compound catabolic process	GO:1901658	206	0.022
amide transport	GO:0042886	138	0.022
nucleoside catabolic process	GO:0009164	206	0.022
muscle cell differentiation	GO:0042692	261	0.022
reactive oxygen species biosynthetic process	GO:1903409	8	0.021
response to transforming growth factor beta	GO:0071559	88	0.021
regulation of chloride transport	GO:2001225	2	0.021
nucleotide metabolic process	GO:0009117	332	0.021
peptide secretion	GO:0002790	114	0.021
epidermis development	GO:0008544	187	0.021
organic cyclic compound catabolic process	GO:1901361	295	0.021
peptide transport	GO:0015833	133	0.021
cellular amine metabolic process	GO:0044106	44	0.021
regulation of proteolysis	GO:0030162	164	0.021
purine ribonucleoside catabolic process	GO:0046130	205	0.021
ribonucleoside metabolic process	GO:0009119	245	0.021
apoptotic signaling pathway	GO:0097190	306	0.020
ribonucleotide metabolic process	GO:0009259	291	0.020
reactive nitrogen species metabolic process	GO:2001057	0	0.020
energy derivation by oxidation of organic compounds	GO:0015980	77	0.020
cellular response to starvation	GO:0009267	57	0.020
cellular ketone metabolic process	GO:0042180	84	0.020
nucleoside triphosphate metabolic process	GO:0009141	230	0.020
regulation of cellular ketone metabolic process	GO:0010565	66	0.020
response to molecule of bacterial origin	GO:0002237	143	0.020
cellular response to carbohydrate stimulus	GO:0071322	50	0.020
methylation	GO:0032259	134	0.020
regulation of ion transport	GO:0043269	215	0.019
acylglycerol metabolic process	GO:0006639	55	0.019
response to lipopolysaccharide	GO:0032496	128	0.019
positive regulation of transforming growth factor beta secretion	GO:2001203	1	0.019
response to peptide	GO:1901652	136	0.019
regulation of microvillus assembly	GO:0032534	3	0.019
cellular response to hexose stimulus	GO:0071331	47	0.019
ribonucleotide catabolic process	GO:0009261	208	0.019
chromatin modification	GO:0016568	187	0.019
positive regulation of cell death	GO:0010942	224	0.019
response to peptide hormone	GO:0043434	127	0.019
chromatin organization	GO:0006325	206	0.018
digestive tract development	GO:0048565	190	0.018
epithelial cell development	GO:0002064	159	0.018
monosaccharide biosynthetic process	GO:0046364	44	0.018
camera type eye development	GO:0043010	266	0.018
olfactory learning	GO:0008355	2	0.018
organelle fission	GO:0048285	170	0.018
glycoprotein metabolic process	GO:0009100	116	0.018
positive regulation of cell cycle	GO:0045787	92	0.018
compound eye development	GO:0048749	1	0.017
positive regulation of cellular amine metabolic process	GO:0033240	5	0.017
positive regulation of protein kinase b signaling	GO:0051897	32	0.017
maintenance of location	GO:0051235	89	0.017
negative regulation of cellular amine metabolic process	GO:0033239	1	0.017
regulation of cell cycle process	GO:0010564	160	0.017
embryonic organ morphogenesis	GO:0048562	276	0.017
cation homeostasis	GO:0055080	212	0.017
histone methylation	GO:0016571	71	0.017
response to insulin	GO:0032868	100	0.016
odontogenesis of dentin containing tooth	GO:0042475	66	0.016	Mouse
visual perception	GO:0007601	52	0.016
cellular response to insulin stimulus	GO:0032869	78	0.016
progesterone metabolic process	GO:0042448	4	0.016
cellular calcium ion homeostasis	GO:0006874	119	0.016
posttranscriptional regulation of gene expression	GO:0010608	155	0.016
negative regulation of myelination	GO:0031642	6	0.016	Mouse
insulin secretion involved in cellular response to glucose stimulus	GO:0035773	36	0.016
regulation of chromatin organization	GO:1902275	57	0.016
regulation of antimicrobial peptide biosynthetic process	GO:0002805	1	0.015
gluconeogenesis	GO:0006094	39	0.015
meiotic cell cycle process	GO:1903046	77	0.015
response to radiation	GO:0009314	165	0.015
regulation of epithelial cell proliferation	GO:0050678	141	0.015
cytoplasmic transport	GO:0016482	234	0.015
glycoprotein biosynthetic process	GO:0009101	89	0.015
insulin receptor signaling pathway	GO:0008286	49	0.015
spermatid differentiation	GO:0048515	115	0.015
organophosphate biosynthetic process	GO:0090407	122	0.015
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.015
phenol containing compound metabolic process	GO:0018958	60	0.015
carbohydrate homeostasis	GO:0033500	128	0.015
odontogenesis	GO:0042476	78	0.015	Mouse
thymocyte migration	GO:0072679	2	0.014
nucleoside phosphate biosynthetic process	GO:1901293	79	0.014
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.014
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.014
nuclear import	GO:0051170	95	0.014
organonitrogen compound catabolic process	GO:1901565	264	0.014
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.014
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.014
positive regulation of cellular carbohydrate metabolic process	GO:0010676	29	0.014
cellular response to gonadotropin stimulus	GO:0071371	4	0.014
histamine induced gastric acid secretion	GO:0001697	1	0.014
tissue homeostasis	GO:0001894	115	0.014
gland development	GO:0048732	330	0.014
angiogenesis	GO:0001525	201	0.014
reactive oxygen species metabolic process	GO:0072593	84	0.014
hematopoietic progenitor cell differentiation	GO:0002244	143	0.014
regulation of hormone secretion	GO:0046883	88	0.014
cellular response to organic cyclic compound	GO:0071407	87	0.014
cardiac ventricle development	GO:0003231	83	0.014	Mouse
cellular glucose homeostasis	GO:0001678	52	0.014
protein localization to organelle	GO:0033365	185	0.014
response to light stimulus	GO:0009416	135	0.014
spermatid development	GO:0007286	108	0.014
retina development in camera type eye	GO:0060041	119	0.014
nucleotide catabolic process	GO:0009166	217	0.014
divalent inorganic cation homeostasis	GO:0072507	138	0.014
positive regulation of eosinophil migration	GO:2000418	2	0.013
positive regulation of nervous system development	GO:0051962	221	0.013
positive regulation of ion transmembrane transport	GO:0034767	24	0.013
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.013
positive regulation of hydrolase activity	GO:0051345	148	0.013
purine nucleotide catabolic process	GO:0006195	211	0.013
regulation of lipid biosynthetic process	GO:0046890	54	0.013
nucleoside triphosphate catabolic process	GO:0009143	205	0.013
response to follicle stimulating hormone	GO:0032354	1	0.013
metal ion homeostasis	GO:0055065	189	0.013
cellular response to nutrient levels	GO:0031669	64	0.013
regulation of cellular amine metabolic process	GO:0033238	20	0.013
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.013
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.013
immune effector process	GO:0002252	321	0.013
sensory perception	GO:0007600	245	0.013
cellular response to cytokine stimulus	GO:0071345	189	0.013
regulation of vesicle mediated transport	GO:0060627	139	0.013
carboxylic acid catabolic process	GO:0046395	51	0.013
peptide hormone secretion	GO:0030072	109	0.013
negative regulation of feeding behavior	GO:2000252	1	0.013
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.013
covalent chromatin modification	GO:0016569	163	0.013
negative regulation of homeostatic process	GO:0032845	71	0.013
rhodopsin mediated signaling pathway	GO:0016056	4	0.013
asymmetric stem cell division	GO:0098722	3	0.013
blood vessel morphogenesis	GO:0048514	285	0.013
positive regulation of proteolysis	GO:0045862	85	0.013
striated muscle cell development	GO:0055002	125	0.013
neurotransmitter transport	GO:0006836	76	0.013
guanosine containing compound metabolic process	GO:1901068	144	0.013
calcium ion dependent exocytosis	GO:0017156	35	0.013
catecholamine metabolic process	GO:0006584	30	0.013
cellular response to glucose stimulus	GO:0071333	45	0.012
nucleoside metabolic process	GO:0009116	246	0.012
pancreas development	GO:0031016	57	0.012
multi multicellular organism process	GO:0044706	109	0.012
positive regulation of apoptotic process	GO:0043065	217	0.012
regulation of multi organism process	GO:0043900	111	0.012
second messenger mediated signaling	GO:0019932	73	0.012
positive regulation of thymocyte migration	GO:2000412	2	0.012
tissue remodeling	GO:0048771	102	0.012
negative regulation of organelle organization	GO:0010639	90	0.012
dibenzo p dioxin metabolic process	GO:0018894	1	0.012
response to testosterone	GO:0033574	3	0.012
positive regulation of cell motility	GO:2000147	116	0.012
leukocyte migration	GO:0050900	124	0.012
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.012
mitotic cell cycle	GO:0000278	195	0.012
regulation of angiogenesis	GO:0045765	81	0.012
sclerotome development	GO:0061056	4	0.012
carnitine transport	GO:0015879	3	0.012
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.012
regulation of complement activation classical pathway	GO:0030450	1	0.012
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	40	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.012
wound healing	GO:0042060	157	0.012
regulation of cell motility	GO:2000145	236	0.012
retina homeostasis	GO:0001895	23	0.012
eosinophil migration	GO:0072677	3	0.012
cellular nitrogen compound catabolic process	GO:0044270	280	0.012
glucose metabolic process	GO:0006006	92	0.012
prevention of polyspermy	GO:0060468	4	0.012
intracellular mrna localization	GO:0008298	4	0.011
glycosylation	GO:0070085	62	0.011
fat cell proliferation	GO:0070341	4	0.011
regulation of carbohydrate biosynthetic process	GO:0043255	40	0.011
meiotic nuclear division	GO:0007126	115	0.011
skin development	GO:0043588	220	0.011
negative regulation of macrophage apoptotic process	GO:2000110	3	0.011
regulation of leukocyte apoptotic process	GO:2000106	56	0.011
negative regulation of nervous system development	GO:0051961	156	0.011	Mouse
cellular ion homeostasis	GO:0006873	165	0.011
renal system process	GO:0003014	48	0.011
monosaccharide metabolic process	GO:0005996	106	0.011
cellular protein complex assembly	GO:0043623	116	0.011
regulation of ph	GO:0006885	26	0.011
immune response regulating signaling pathway	GO:0002764	125	0.011
nucleoside phosphate metabolic process	GO:0006753	338	0.011
alpha amino acid metabolic process	GO:1901605	59	0.011
ribonucleoside catabolic process	GO:0042454	206	0.011
nuclear division	GO:0000280	158	0.011
intracellular protein transport	GO:0006886	204	0.011
regulation of neurotransmitter levels	GO:0001505	87	0.011
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.011
regulation of peptide transport	GO:0090087	91	0.011
organophosphate catabolic process	GO:0046434	232	0.011
sensory perception of light stimulus	GO:0050953	54	0.011
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.011
peptidyl amino acid modification	GO:0018193	336	0.011
cardiac muscle tissue growth	GO:0055017	37	0.011
adult locomotory behavior	GO:0008344	91	0.011
protein localization to nucleus	GO:0034504	121	0.011
kidney development	GO:0001822	213	0.011
skeletal muscle organ development	GO:0060538	163	0.011
c21 steroid hormone biosynthetic process	GO:0006700	3	0.011
negative regulation of protein metabolic process	GO:0051248	282	0.011
muscle cell development	GO:0055001	133	0.011
dopamine metabolic process	GO:0042417	23	0.011
histone modification	GO:0016570	159	0.011
regulation of cell growth	GO:0001558	91	0.011
synapsis	GO:0007129	34	0.011
glycosyl compound metabolic process	GO:1901657	246	0.011
regulation of calcium ion transport	GO:0051924	69	0.010
regulation of exit from mitosis	GO:0007096	1	0.010
regulation of cell division	GO:0051302	76	0.010
organic hydroxy compound biosynthetic process	GO:1901617	77	0.010
amino acid transmembrane transport	GO:0003333	37	0.010
ras protein signal transduction	GO:0007265	77	0.010
histone acetylation	GO:0016573	41	0.010
sulfur compound metabolic process	GO:0006790	100	0.010
activation of adenylate cyclase activity	GO:0007190	4	0.010
positive regulation of ion transport	GO:0043270	65	0.010
regulation of cellular component biogenesis	GO:0044087	181	0.010
regulation of insulin secretion involved in cellular response to glucose stimulus	GO:0061178	31	0.010
ameboidal type cell migration	GO:0001667	128	0.010
activation of immune response	GO:0002253	138	0.010
positive regulation of epithelial cell proliferation	GO:0050679	68	0.010
positive regulation of cellular catabolic process	GO:0031331	148	0.010
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.010
fatty acid metabolic process	GO:0006631	121	0.010
cofactor metabolic process	GO:0051186	80	0.010
regulation of antimicrobial peptide production	GO:0002784	1	0.010
cellular response to follicle stimulating hormone stimulus	GO:0071372	1	0.010
dna metabolic process	GO:0006259	303	0.010
organic hydroxy compound transport	GO:0015850	93	0.010
positive regulation of protein kinase activity	GO:0045860	144	0.010
b cell activation	GO:0042113	161	0.010
pigmentation	GO:0043473	71	0.010

Klk1b16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
musculoskeletal system disease	DOID:17	0.018
connective tissue disease	DOID:65	0.018
disease of anatomical entity	DOID:7	0.018
bone disease	DOID:0080001	0.015
cancer	DOID:162	0.010
disease of cellular proliferation	DOID:14566	0.010
organ system cancer	DOID:0050686	0.010

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