Mus musculus

6 known processes

Pot1a

protection of telomeres 1A

(Aliases: AI851169,1500031H18Rik,Pot1)

Pot1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protection from non homologous end joining at telomereGO:003184840.988
Mouse
ubiquitin dependent protein catabolic processGO:00065111290.104
anatomical structure homeostasisGO:00602491450.096
Mouse
cellular macromolecule catabolic processGO:00442652060.096
methylationGO:00322591340.095
chromatin organizationGO:00063252060.093
modification dependent macromolecule catabolic processGO:00436321330.092
telomere maintenanceGO:0000723190.071
Mouse
chromatin modificationGO:00165681870.068
organonitrogen compound catabolic processGO:19015652640.067
dna metabolic processGO:00062593030.064
Mouse
microtubule polymerization or depolymerizationGO:0031109260.064
regulation of microtubule polymerization or depolymerizationGO:0031110200.063
histone modificationGO:00165701590.063
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.062
telomere maintenance in response to dna damageGO:004324740.062
Mouse
mitotic cell cycleGO:00002781950.061
microtubule cytoskeleton organizationGO:00002261570.060
macromolecule catabolic processGO:00090572810.059
negative regulation of cellular protein metabolic processGO:00322692470.059
protein polymerizationGO:0051258570.054
regulation of organelle organizationGO:00330432890.054
mitotic spindle checkpointGO:007117490.052
regulation of chromosome organizationGO:0033044830.052
regulation of microtubule based processGO:0032886520.051
locomotory behaviorGO:00076261950.050
protein oligomerizationGO:0051259670.050
regulation of microtubule polymerizationGO:003111370.048
regulation of transferase activityGO:00513382630.045
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.045
cellular response to dna damage stimulusGO:00069742070.045
Mouse
protein maturationGO:00516041760.044
microtubule based processGO:00070172360.043
negative regulation of cellular component organizationGO:00511291940.043
nucleobase containing small molecule metabolic processGO:00550863520.043
regulation of cellular catabolic processGO:00313292420.042
negative regulation of dna replicationGO:000815640.041
regulation of mitotic cell cycleGO:00073461260.041
regulation of cellular component biogenesisGO:00440871810.041
telomere cappingGO:001623340.041
Mouse
apoptotic signaling pathwayGO:00971903060.040
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.040
proteolysis involved in cellular protein catabolic processGO:00516031470.040
proteasomal protein catabolic processGO:0010498980.040
nuclear divisionGO:00002801580.039
protein catabolic processGO:00301632210.039
aromatic compound catabolic processGO:00194392860.039
regionalizationGO:00030023370.039
telomere maintenance via telomeraseGO:000700410.039
ribose phosphate metabolic processGO:00196932910.039
nucleoside metabolic processGO:00091162460.039
purine nucleotide metabolic processGO:00061633020.038
cellular protein catabolic processGO:00442571550.038
dna biosynthetic processGO:0071897220.038
glycosyl compound metabolic processGO:19016572460.037
multicellular organismal homeostasisGO:00488711640.037
ribonucleoside triphosphate metabolic processGO:00091992200.037
rna dependent dna replicationGO:000627830.037
regulation of cell cycleGO:00517262810.036
negative regulation of molecular functionGO:00440922580.036
dna replicationGO:0006260520.036
leukocyte differentiationGO:00025213420.036
mitotic cell cycle processGO:19030471590.036
negative regulation of protein metabolic processGO:00512482820.035
negative regulation of organelle organizationGO:0010639900.035
organelle fissionGO:00482851700.034
tissue homeostasisGO:00018941150.033
vacuole organizationGO:0007033380.033
peptide metabolic processGO:0006518460.033
cellular protein complex assemblyGO:00436231160.033
regulation of cellular amino acid metabolic processGO:000652150.033
regulation of proteolysisGO:00301621640.032
negative regulation of cellular catabolic processGO:0031330470.032
organic cyclic compound catabolic processGO:19013612950.032
protein processingGO:00164851630.032
regulation of protein catabolic processGO:00421761080.032
nucleoside phosphate metabolic processGO:00067533380.031
microtubule polymerizationGO:0046785120.031
cellular amine metabolic processGO:0044106440.031
ribonucleotide catabolic processGO:00092612080.031
regulation of cell cycle processGO:00105641600.030
purine ribonucleoside triphosphate metabolic processGO:00092052200.029
negative regulation of transferase activityGO:0051348850.029
purine ribonucleotide catabolic processGO:00091542080.029
ras protein signal transductionGO:0007265770.028
positive regulation of organelle organizationGO:00106381280.028
regulation of nuclear divisionGO:0051783560.028
positive regulation of cell deathGO:00109422240.028
peptidyl amino acid modificationGO:00181933360.028
carbohydrate derivative catabolic processGO:19011362310.028
regulation of proteasomal protein catabolic processGO:0061136460.028
purine nucleoside metabolic processGO:00422782410.028
negative regulation of chromosome organizationGO:2001251300.027
nucleoside catabolic processGO:00091642060.027
embryonic organ morphogenesisGO:00485622760.027
regulation of cytoskeleton organizationGO:00514931220.027
purine containing compound catabolic processGO:00725232130.027
regulation of homeostatic processGO:00328441820.027
cellular ketone metabolic processGO:0042180840.027
ribonucleotide metabolic processGO:00092592910.027
covalent chromatin modificationGO:00165691630.027
nucleoside triphosphate metabolic processGO:00091412300.026
ribonucleoside metabolic processGO:00091192450.026
organophosphate catabolic processGO:00464342320.026
regulation of cellular protein catabolic processGO:1903362610.026
positive regulation of chromosome organizationGO:2001252330.026
regulation of protein maturationGO:1903317960.026
heterocycle catabolic processGO:00467002800.026
protein homooligomerizationGO:0051260430.026
cellular amino acid metabolic processGO:00065201030.026
cell divisionGO:00513011200.026
amine metabolic processGO:0009308450.025
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.025
histone methylationGO:0016571710.025
positive regulation of cellular component biogenesisGO:0044089940.025
immune effector processGO:00022523210.025
nucleotide catabolic processGO:00091662170.025
t cell activationGO:00421102890.025
positive regulation of cellular amine metabolic processGO:003324050.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
macromolecule methylationGO:00434141200.025
negative regulation of nuclear divisionGO:0051784190.025
lymphocyte differentiationGO:00300982420.024
negative regulation of protein processingGO:0010955790.024
purine ribonucleoside catabolic processGO:00461302050.024
purine nucleoside triphosphate catabolic processGO:00091462030.024
nucleotide metabolic processGO:00091173320.024
positive regulation of programmed cell deathGO:00430682180.024
negative regulation of proteolysisGO:0045861740.023
positive regulation of microtubule polymerization or depolymerizationGO:003111230.023
regulation of protein processingGO:0070613960.023
regulation of apoptotic signaling pathwayGO:20012331970.023
purine ribonucleoside triphosphate catabolic processGO:00092071990.023
protein methylationGO:0006479810.023
regulation of cell divisionGO:0051302760.023
purine containing compound metabolic processGO:00725213110.023
regulation of mitotic cell cycle phase transitionGO:1901990730.022
purine ribonucleoside metabolic processGO:00461282410.022
negative regulation of protein maturationGO:1903318790.022
skeletal system developmentGO:00015013560.022
positive regulation of protein complex assemblyGO:0031334450.022
regulation of cellular amine metabolic processGO:0033238200.022
negative regulation of homeostatic processGO:0032845710.022
protein alkylationGO:0008213810.022
negative regulation of cell cycle processGO:0010948690.022
chromosome separationGO:0051304140.022
histone lysine methylationGO:0034968500.022
ribonucleoside triphosphate catabolic processGO:00092031990.021
mitotic nuclear divisionGO:0007067480.021
purine nucleoside catabolic processGO:00061522050.021
b cell activationGO:00421131610.021
sensory organ morphogenesisGO:00905962420.021
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051220.021
negative regulation of cell cycleGO:00457861230.021
positive regulation of homeostatic processGO:0032846640.021
positive regulation of protein modification processGO:00314012990.021
regulation of cell cycle phase transitionGO:1901987770.020
mitotic cell cycle checkpointGO:0007093310.020
gland developmentGO:00487323300.020
negative regulation of mitotic cell cycleGO:0045930580.020
protein modification by small protein conjugation or removalGO:00706472070.020
cellular nitrogen compound catabolic processGO:00442702800.020
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435150.020
sensory perceptionGO:00076002450.020
epithelial tube morphogenesisGO:00605623030.020
protein ubiquitinationGO:00165671710.020
ribonucleoside catabolic processGO:00424542060.020
mitotic sister chromatid separationGO:005130690.020
purine ribonucleotide metabolic processGO:00091502900.020
negative regulation of cellular protein catabolic processGO:1903363220.020
positive regulation of apoptotic processGO:00430652170.019
nucleoside triphosphate catabolic processGO:00091432050.019
cation transportGO:00068123990.019
positive regulation of microtubule polymerizationGO:003111630.019
regulation of cell activationGO:00508652890.019
small gtpase mediated signal transductionGO:0007264970.019
stem cell developmentGO:00488642190.019
protein modification by small protein conjugationGO:00324461870.018
nucleoside phosphate catabolic processGO:19012922220.018
cell cycle checkpointGO:0000075470.018
positive regulation of cell developmentGO:00107202370.018
transmembrane transportGO:00550854120.018
regulation of cytokine productionGO:00018172660.018
camera type eye developmentGO:00430102660.018
lysosome organizationGO:0007040210.018
purine ribonucleoside monophosphate metabolic processGO:0009167800.017
regulation of cellular ketone metabolic processGO:0010565660.017
mapk cascadeGO:00001652810.017
sister chromatid segregationGO:0000819200.017
chromosome segregationGO:0007059480.017
positive regulation of cytoskeleton organizationGO:0051495490.017
positive regulation of nervous system developmentGO:00519622210.017
neuromuscular processGO:0050905990.017
purine nucleoside triphosphate metabolic processGO:00091442260.017
regulation of t cell activationGO:00508631700.016
glycosyl compound catabolic processGO:19016582060.016
purine nucleotide catabolic processGO:00061952110.016
peptidyl lysine modificationGO:0018205770.016
cellular response to lipidGO:00713961450.016
cytoplasmic transportGO:00164822340.016
g protein coupled receptor signaling pathwayGO:00071862430.016
regulation of neuron differentiationGO:00456642810.016
neuromuscular process controlling balanceGO:0050885590.016
regulation of cell migrationGO:00303342190.016
spermatogenesisGO:00072832840.016
regulation of cell motilityGO:20001452360.016
response to organonitrogen compoundGO:00102432460.016
positive regulation of cell cycle processGO:0090068610.016
appendage morphogenesisGO:00351071490.016
urogenital system developmentGO:00016552610.016
compound eye developmentGO:004874910.015
cellular amide metabolic processGO:0043603580.015
positive regulation of nuclear divisionGO:0051785270.015
respiratory system developmentGO:00605411900.015
appendage developmentGO:00487361660.015
negative regulation of cell cycle phase transitionGO:1901988480.015
cation transmembrane transportGO:00986552660.015
metaphase anaphase transition of mitotic cell cycleGO:000709190.015
cytokine productionGO:00018163190.015
heart morphogenesisGO:00030071780.015
mitotic sister chromatid segregationGO:0000070140.015
regulation of dna methylationGO:0044030120.015
negative regulation of cell proliferationGO:00082852960.015
negative regulation of protein catabolic processGO:0042177360.015
nucleoside monophosphate metabolic processGO:0009123850.015
blood circulationGO:00080151950.014
regulation of mitosisGO:0007088290.014
intracellular protein transportGO:00068862040.014
morphogenesis of embryonic epitheliumGO:00163311590.014
positive regulation of cell cycleGO:0045787920.014
regulation of telomerase activityGO:005197210.014
atp metabolic processGO:0046034750.014
regulation of lymphocyte activationGO:00512492400.014
cell type specific apoptotic processGO:00972852680.014
ear developmentGO:00435832000.014
axonogenesisGO:00074092740.014
forebrain developmentGO:00309003020.014
leukocyte activation involved in immune responseGO:00023661260.014
coenzyme a metabolic processGO:001593680.014
negative regulation of cell divisionGO:0051782240.013
regulation of chromosome segregationGO:0051983210.013
dna alkylationGO:0006305430.013
protein acylationGO:0043543640.013
leukocyte mediated immunityGO:00024431740.013
ossificationGO:00015032160.013
positive regulation of cell activationGO:00508671580.013
renal system developmentGO:00720012250.013
purine nucleoside monophosphate catabolic processGO:0009128580.013
regulation of histone modificationGO:0031056560.013
intrinsic apoptotic signaling pathwayGO:00971931320.013
inflammatory responseGO:00069542440.013
neuron deathGO:00709971540.013
organonitrogen compound biosynthetic processGO:19015661920.013
dna modificationGO:0006304500.013
membrane organizationGO:00610242450.013
lymphocyte activation involved in immune responseGO:0002285930.013
dna catabolic process endonucleolyticGO:0000737150.013
maintenance of locationGO:0051235890.013
regulation of sister chromatid segregationGO:0033045130.013
cellular response to growth factor stimulusGO:00713631970.013
response to growth factorGO:00708481980.013
response to radiationGO:00093141650.013
dna methylationGO:0006306430.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.012
bone remodelingGO:0046849530.012
positive regulation of cell divisionGO:0051781310.012
mitochondrion organizationGO:00070051340.012
negative regulation of cellular amine metabolic processGO:003323910.012
regulation of chromatin modificationGO:1903308570.012
organelle assemblyGO:00709251770.012
regulation of secretionGO:00510462740.012
reactive oxygen species metabolic processGO:0072593840.012
t cell differentiationGO:00302171740.012
meiotic nuclear divisionGO:00071261150.012
nitrogen compound transportGO:00717052710.012
organelle localizationGO:00516401790.012
embryonic appendage morphogenesisGO:00351131260.012
circulatory system processGO:00030131970.012
smoothened signaling pathwayGO:00072241050.012
leukocyte proliferationGO:00706611720.012
posttranscriptional regulation of gene expressionGO:00106081550.012
negative regulation of protein modification processGO:00314001630.012
protein localization to organelleGO:00333651850.012
trna wobble base modificationGO:000209720.012
atp catabolic processGO:0006200550.012
negative regulation of cell developmentGO:00107211690.012
regulation of synaptic growth at neuromuscular junctionGO:000858240.012
intestinal epithelial structure maintenanceGO:006072940.012
negative regulation of mitotic cell cycle phase transitionGO:1901991450.012
divalent inorganic cation transportGO:00725111780.012
negative regulation of intracellular signal transductionGO:19025321670.012
regulation of histone methylationGO:0031060300.012
rho protein signal transductionGO:0007266320.012
cellular homeostasisGO:00197252400.012
lung developmentGO:00303241640.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
negative regulation of growthGO:0045926990.012
regulation of secretion by cellGO:19035302490.012
blood vessel morphogenesisGO:00485142850.012
regulation of membrane potentialGO:00423911920.012
positive regulation of transferase activityGO:00513471670.011
regulation of cellular response to growth factor stimulusGO:0090287820.011
regulation of system processGO:00440572000.011
response to light stimulusGO:00094161350.011
respiratory tube developmentGO:00303231670.011
oxidation reduction processGO:00551143420.011
regulation of mapk cascadeGO:00434082480.011
epithelial cell proliferationGO:00506731740.011
ion transmembrane transportGO:00342203610.011
neural tube developmentGO:00219151600.011
neural precursor cell proliferationGO:00613511210.011
lateral inhibitionGO:004633110.011
morphogenesis of a branching epitheliumGO:00611381930.011
positive regulation of hydrolase activityGO:00513451480.011
cellular response to molecule of bacterial originGO:0071219830.011
purine nucleoside monophosphate metabolic processGO:0009126810.011
developmental growth involved in morphogenesisGO:00605601380.011
male gamete generationGO:00482322850.011
wound healingGO:00420601570.011
bone resorptionGO:0045453380.011
skeletal muscle organ developmentGO:00605381630.011
carbohydrate derivative biosynthetic processGO:19011371830.011
negative regulation of neuron deathGO:1901215980.011
positive regulation of mitotic cell cycleGO:0045931410.011
embryonic limb morphogenesisGO:00303261260.011
cellular response to hormone stimulusGO:00328701500.011
nucleoside monophosphate catabolic processGO:0009125590.011
developmental maturationGO:00217001930.011
blastocyst developmentGO:0001824800.011
regulation of hydrolase activityGO:00513362460.011
chemotaxisGO:00069352470.011
positive regulation of mapk cascadeGO:00434101700.011
limb morphogenesisGO:00351081490.011
cellular response to gamma radiationGO:007148040.011
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.011
dendrite developmentGO:00163581150.011
cilium morphogenesisGO:00602711020.011
cellular response to transforming growth factor beta stimulusGO:0071560880.011
multicellular organism growthGO:00352641610.011
epithelial tube formationGO:00721751300.011
cellular response to organonitrogen compoundGO:00714171450.011
muscle system processGO:00030121410.010
spindle checkpointGO:0031577120.010
anion transportGO:00068201770.010
b cell differentiationGO:0030183780.010
cellular lipid metabolic processGO:00442553230.010
cell cycle g2 m phase transitionGO:0044839200.010
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:003114590.010
negative regulation of immune system processGO:00026832090.010
response to acid chemicalGO:00011011110.010
endocytosisGO:00068971680.010
segmentationGO:0035282930.010
engulfment of apoptotic cellGO:004365230.010
regulation of metaphase anaphase transition of cell cycleGO:190209990.010
regulation of leukocyte mediated immunityGO:00027031040.010
response to lipopolysaccharideGO:00324961280.010
embryonic placenta developmentGO:0001892980.010
placenta developmentGO:00018901400.010
regulation of neuron apoptotic processGO:00435231220.010

Pot1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.029
inherited metabolic disorderDOID:65500.029
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.021
immune system diseaseDOID:291400.019
central nervous system diseaseDOID:33100.013
disease of cellular proliferationDOID:1456600.013
sensory system diseaseDOID:005015500.011
hematopoietic system diseaseDOID:7400.010
cancerDOID:16200.010