Mus musculus

0 known processes

Gen1

Gen homolog 1, endonuclease (Drosophila)

(Aliases: 5830483C08Rik,MGC115970)

Gen1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742070.112
Human Fly
meiotic cell cycle processGO:1903046770.104
male gamete generationGO:00482322850.102
negative regulation of fibroblast apoptotic processGO:200027060.100
protein catabolic processGO:00301632210.089
meiotic cell cycleGO:00513211220.084
meiotic nuclear divisionGO:00071261150.075
organelle fissionGO:00482851700.068
regulation of organelle organizationGO:00330432890.064
Human
spermatid differentiationGO:00485151150.056
cellular amine metabolic processGO:0044106440.054
microtubule based processGO:00070172360.053
Human
cellular response to gamma radiationGO:007148040.052
chromosome segregationGO:0007059480.044
microtubule cytoskeleton organizationGO:00002261570.044
Human
regulation of cell cycleGO:00517262810.044
Human
cellular ketone metabolic processGO:0042180840.041
amine metabolic processGO:0009308450.040
double strand break repairGO:0006302480.039
Human Fly
dna repairGO:00062811070.039
Human Fly
mitotic cell cycle processGO:19030471590.037
Human
cilium assemblyGO:0042384810.037
regulation of cellular amino acid metabolic processGO:000652150.034
regulation of cell cycle processGO:00105641600.033
Human
meiosis iGO:0007127600.033
germ cell developmentGO:00072811850.033
negative regulation of cellular protein metabolic processGO:00322692470.032
Human
negative regulation of cellular component organizationGO:00511291940.032
Human
intrinsic apoptotic signaling pathwayGO:00971931320.031
centrosome organizationGO:0051297260.031
Human
protein modification by small protein conjugation or removalGO:00706472070.029
spermatid developmentGO:00072861080.029
protein maturationGO:00516041760.027
regulation of protein catabolic processGO:00421761080.027
Human
protein methylationGO:0006479810.026
positive regulation of cellular amino acid metabolic processGO:004576430.025
regulation of cellular amine metabolic processGO:0033238200.025
regulation of protein maturationGO:1903317960.025
Human
spermatogenesisGO:00072832840.025
negative regulation of cell divisionGO:0051782240.025
Human
protein modification by small protein conjugationGO:00324461870.025
establishment of organelle localizationGO:00516561220.025
nucleobase containing small molecule metabolic processGO:00550863520.024
negative regulation of protein catabolic processGO:0042177360.024
Human
nuclear divisionGO:00002801580.024
lateral inhibitionGO:004633110.024
dna recombinationGO:0006310920.024
Human
macromolecule catabolic processGO:00090572810.022
Human Fly
cellular amino acid metabolic processGO:00065201030.021
regulation of cellular protein catabolic processGO:1903362610.021
Human
regulation of cellular ketone metabolic processGO:0010565660.021
regulation of mitotic cell cycle phase transitionGO:1901990730.021
Human
protein polyubiquitinationGO:0000209330.020
negative regulation of ubiquitin protein transferase activityGO:005144430.020
organelle assemblyGO:00709251770.020
synapsisGO:0007129340.020
carbohydrate derivative catabolic processGO:19011362310.020
regulation of chromosome organizationGO:0033044830.019
Human
nucleotide metabolic processGO:00091173320.019
negative regulation of transferase activityGO:0051348850.019
negative regulation of protein metabolic processGO:00512482820.019
Human
mitotic cell cycleGO:00002781950.018
Human
male meiosis iGO:0007141160.018
nucleoside phosphate metabolic processGO:00067533380.018
modification dependent macromolecule catabolic processGO:00436321330.018
chromosome organization involved in meiosisGO:0070192390.018
dna metabolic processGO:00062593030.017
Human Fly
positive regulation of mitotic cell cycleGO:0045931410.017
Human
methylationGO:00322591340.017
regulation of microtubule based processGO:0032886520.017
Human
negative regulation of organelle organizationGO:0010639900.017
Human
purine nucleoside metabolic processGO:00422782410.017
response to uvGO:0009411440.016
negative regulation of cell cycleGO:00457861230.016
Human
negative regulation of cell cycle phase transitionGO:1901988480.016
Human
cell divisionGO:00513011200.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
positive regulation of nfat protein import into nucleusGO:005153310.016
negative regulation of cell proliferationGO:00082852960.016
positive regulation of programmed cell deathGO:00430682180.016
telencephalon developmentGO:00215371860.016
lymphocyte mediated immunityGO:00024491390.016
negative regulation of cellular protein catabolic processGO:1903363220.016
Human
positive regulation of cell deathGO:00109422240.015
negative regulation of ligase activityGO:005135230.015
organophosphate catabolic processGO:00464342320.015
mitotic cell cycle arrestGO:007185040.015
leukocyte mediated immunityGO:00024431740.015
negative regulation of proteolysisGO:0045861740.015
Human
cytoplasmic transportGO:00164822340.015
nucleotide catabolic processGO:00091662170.015
cellular macromolecule catabolic processGO:00442652060.015
Human Fly
b cell activationGO:00421131610.015
mitotic sister chromatid segregationGO:0000070140.015
positive regulation of apoptotic processGO:00430652170.015
protein ubiquitinationGO:00165671710.015
microtubule organizing center organizationGO:0031023280.015
Human
protein processingGO:00164851630.015
organonitrogen compound catabolic processGO:19015652640.015
histone h3 k9 dimethylationGO:003612340.015
purine nucleoside monophosphate metabolic processGO:0009126810.014
regulation of nuclear divisionGO:0051783560.014
Human
positive regulation of cellular amine metabolic processGO:003324050.014
stem cell differentiationGO:00488632680.014
glycosyl compound metabolic processGO:19016572460.014
adaptive immune responseGO:00022501550.014
ribonucleoside metabolic processGO:00091192450.014
nucleoside phosphate catabolic processGO:19012922220.014
stem cell maintenanceGO:00198271300.014
protein alkylationGO:0008213810.014
ribose phosphate metabolic processGO:00196932910.014
blastocyst developmentGO:0001824800.014
response to nutrient levelsGO:00316671090.013
ubiquitin dependent protein catabolic processGO:00065111290.013
regulation of adaptive immune responseGO:0002819900.013
cell cycle switchingGO:006018410.013
spindle assembly involved in meiosisGO:009030640.013
forebrain developmentGO:00309003020.013
purine nucleoside monophosphate catabolic processGO:0009128580.013
production of molecular mediator of immune responseGO:00024401030.013
intracellular protein transportGO:00068862040.013
nitrogen compound transportGO:00717052710.013
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051220.012
Human
purine nucleoside triphosphate catabolic processGO:00091462030.012
nucleoside metabolic processGO:00091162460.012
nucleoside triphosphate catabolic processGO:00091432050.012
negative regulation of mitotic cell cycleGO:0045930580.012
Human
stem cell developmentGO:00488642190.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
regulation of mitotic cell cycleGO:00073461260.012
Human
regulation of cell cycle g2 m phase transitionGO:1902749100.012
negative regulation of protein processingGO:0010955790.012
Human
regulation of lymphocyte activationGO:00512492400.012
regulation of cell cycle phase transitionGO:1901987770.012
Human
mitotic sister chromatid cohesionGO:000706410.011
regulation of establishment of protein localizationGO:00702011810.011
macromolecule methylationGO:00434141200.011
bone developmentGO:00603481200.011
glucose homeostasisGO:00425931280.011
nucleoside catabolic processGO:00091642060.011
purine containing compound metabolic processGO:00725213110.011
regulation of apoptotic signaling pathwayGO:20012331970.011
ribonucleotide catabolic processGO:00092612080.011
response to gamma radiationGO:0010332220.011
apoptotic signaling pathwayGO:00971903060.011
atp metabolic processGO:0046034750.011
cilium morphogenesisGO:00602711020.011
purine ribonucleotide catabolic processGO:00091542080.011
positive regulation of lymphocyte activationGO:00512511400.011
regulation of microtubule cytoskeleton organizationGO:0070507370.011
Human
response to hydroperoxideGO:003319460.011
regulation of cellular component biogenesisGO:00440871810.011
regulation of cell activationGO:00508652890.011
nucleoside monophosphate catabolic processGO:0009125590.011
nuclear transportGO:00511691390.011
divalent metal ion transportGO:00708381720.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
negative regulation of cell cycle processGO:0010948690.011
Human
somatic diversification of immune receptorsGO:0002200530.010
regulation of leukocyte mediated immunityGO:00027031040.010
ribonucleoside triphosphate metabolic processGO:00091992200.010
heterochromatin organizationGO:007082840.010
cellular protein complex assemblyGO:00436231160.010
cellular response to hydroperoxideGO:007144740.010
protein localization to organelleGO:00333651850.010
negative regulation of chromosome organizationGO:2001251300.010
Human

Gen1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
hematopoietic system diseaseDOID:7400.164
immune system diseaseDOID:291400.164
disease of anatomical entityDOID:700.164
organ system cancerDOID:005068600.025
disease of cellular proliferationDOID:1456600.025
cancerDOID:16200.025
anemiaDOID:235500.025
congenital hypoplastic anemiaDOID:134200.024
bone marrow diseaseDOID:496100.024
aplastic anemiaDOID:1244900.024
breast cancerDOID:161200.023
thoracic cancerDOID:509300.023
blood platelet diseaseDOID:221800.013
hemorrhagic diseaseDOID:221300.013
blood coagulation diseaseDOID:124700.013
fanconi s anemiaDOID:1363600.011
nervous system diseaseDOID:86300.010