Mus musculus

171 known processes

Pde2a

phosphodiesterase 2A, cGMP-stimulated

(Aliases: MGC102210)

Pde2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small gtpase mediated signal transductionGO:0007264970.223
ras protein signal transductionGO:0007265770.173
ion transmembrane transportGO:00342203610.160
organic cyclic compound catabolic processGO:19013612950.125
ribonucleotide catabolic processGO:00092612080.124
purine ribonucleotide metabolic processGO:00091502900.123
nucleoside catabolic processGO:00091642060.108
purine ribonucleoside triphosphate catabolic processGO:00092071990.104
purine nucleoside catabolic processGO:00061522050.101
organophosphate catabolic processGO:00464342320.099
aromatic compound catabolic processGO:00194392860.096
heterocycle catabolic processGO:00467002800.095
glycosyl compound catabolic processGO:19016582060.095
nucleotide metabolic processGO:00091173320.094
transmembrane transportGO:00550854120.094
ribose phosphate metabolic processGO:00196932910.093
amine metabolic processGO:0009308450.090
nucleobase containing small molecule metabolic processGO:00550863520.089
carbohydrate derivative catabolic processGO:19011362310.088
purine ribonucleoside metabolic processGO:00461282410.088
purine nucleotide metabolic processGO:00061633020.087
nucleoside metabolic processGO:00091162460.087
nucleoside triphosphate metabolic processGO:00091412300.085
positive regulation of gtp catabolic processGO:0033126850.083
cellular amine metabolic processGO:0044106440.082
purine nucleoside triphosphate catabolic processGO:00091462030.081
purine nucleoside triphosphate metabolic processGO:00091442260.080
purine ribonucleotide catabolic processGO:00091542080.079
ribonucleoside metabolic processGO:00091192450.079
purine containing compound metabolic processGO:00725213110.078
glycosyl compound metabolic processGO:19016572460.077
nucleoside phosphate metabolic processGO:00067533380.077
purine ribonucleoside triphosphate metabolic processGO:00092052200.077
nucleotide catabolic processGO:00091662170.077
ribonucleoside catabolic processGO:00424542060.076
g protein coupled receptor signaling pathwayGO:00071862430.076
cation transmembrane transportGO:00986552660.074
regulation of cellular catabolic processGO:00313292420.072
purine ribonucleoside catabolic processGO:00461302050.071
cellular nitrogen compound catabolic processGO:00442702800.071
purine containing compound catabolic processGO:00725232130.070
regulation of gtp catabolic processGO:00331241130.068
ribonucleotide metabolic processGO:00092592910.068
regulation of cellular ketone metabolic processGO:0010565660.068
gtp metabolic processGO:00460391440.066
ribonucleoside triphosphate metabolic processGO:00091992200.065
purine nucleoside metabolic processGO:00422782410.063
positive regulation of cellular catabolic processGO:00313311480.063
cation transportGO:00068123990.063
negative regulation of cellular component organizationGO:00511291940.060
regulation of purine nucleotide catabolic processGO:00331211220.060
organonitrogen compound catabolic processGO:19015652640.060
regulation of cellular amino acid metabolic processGO:000652150.060
ribonucleoside triphosphate catabolic processGO:00092031990.060
regulation of cellular amine metabolic processGO:0033238200.060
purine nucleotide catabolic processGO:00061952110.059
regulation of ras protein signal transductionGO:00465781140.058
regulation of ras gtpase activityGO:0032318880.056
gtp catabolic processGO:00061841430.055
regulation of hydrolase activityGO:00513362460.054
cellular ketone metabolic processGO:0042180840.054
guanosine containing compound metabolic processGO:19010681440.054
positive regulation of ras gtpase activityGO:0032320650.054
mapk cascadeGO:00001652810.053
Mouse
negative regulation of phosphorus metabolic processGO:00105631840.053
regulation of purine nucleotide metabolic processGO:19005421690.052
divalent inorganic cation transportGO:00725111780.052
cellular amino acid metabolic processGO:00065201030.051
cellular lipid metabolic processGO:00442553230.050
nucleoside triphosphate catabolic processGO:00091432050.050
inorganic ion transmembrane transportGO:00986602340.050
guanosine containing compound catabolic processGO:19010691440.049
positive regulation of gtpase activityGO:0043547850.049
nucleoside phosphate catabolic processGO:19012922220.048
actin cytoskeleton organizationGO:00300362200.047
inorganic cation transmembrane transportGO:00986622070.047
synaptic transmissionGO:00072683290.045
regulation of organelle organizationGO:00330432890.044
immune effector processGO:00022523210.044
positive regulation of nucleotide catabolic processGO:0030813880.044
positive regulation of cellular amino acid metabolic processGO:004576430.044
regulation of nucleoside metabolic processGO:00091181300.043
regulation of cell projection organizationGO:00313442060.043
regulation of cytokine productionGO:00018172660.042
regulation of ion transportGO:00432692150.041
rap protein signal transductionGO:003248630.041
negative regulation of molecular functionGO:00440922580.041
forebrain developmentGO:00309003020.040
regulation of kinase activityGO:00435492490.040
Mouse
response to organonitrogen compoundGO:00102432460.039
rho protein signal transductionGO:0007266320.039
negative regulation of phosphate metabolic processGO:00459361840.039
divalent metal ion transportGO:00708381720.038
positive regulation of cellular amine metabolic processGO:003324050.038
cytoplasmic transportGO:00164822340.038
Rat
cytokine productionGO:00018163190.038
positive regulation of nucleoside metabolic processGO:0045979910.037
regulation of nucleotide metabolic processGO:00061401690.037
negative regulation of protein metabolic processGO:00512482820.037
positive regulation of purine nucleotide metabolic processGO:19005441140.036
regulation of transferase activityGO:00513382630.036
Mouse
negative regulation of cell proliferationGO:00082852960.036
Mouse
membrane organizationGO:00610242450.035
endocytosisGO:00068971680.035
regulation of nucleotide catabolic processGO:00308111220.035
oxidation reduction processGO:00551143420.034
cell adhesionGO:00071553290.034
positive regulation of nucleotide metabolic processGO:00459811140.034
regulation of secretion by cellGO:19035302490.033
regulation of cell motilityGO:20001452360.033
negative regulation of cellular protein metabolic processGO:00322692470.033
organonitrogen compound biosynthetic processGO:19015661920.032
maintenance of locationGO:0051235890.032
positive regulation of hydrolase activityGO:00513451480.031
regulation of lymphocyte activationGO:00512492400.031
Mouse
regulation of membrane potentialGO:00423911920.031
regulation of homeostatic processGO:00328441820.031
positive regulation of cell developmentGO:00107202370.031
Mouse
t cell activationGO:00421102890.030
Mouse
nuclear divisionGO:00002801580.030
dephosphorylationGO:00163111290.030
positive regulation of protein modification processGO:00314012990.030
Mouse
regulation of secretionGO:00510462740.029
calcium ion transportGO:00068161590.029
cellular homeostasisGO:00197252400.029
regulation of protein kinase activityGO:00458592320.029
Mouse
leukocyte proliferationGO:00706611720.028
Mouse
male gamete generationGO:00482322850.028
regulation of defense responseGO:00313472330.028
negative regulation of protein phosphorylationGO:00019331260.028
multicellular organismal signalingGO:0035637910.028
blood circulationGO:00080151950.027
Mouse
regulation of ion transmembrane transportGO:00347651190.027
muscle tissue developmentGO:00605373080.026
regulation of transmembrane transportGO:00347621280.026
regulation of protein localizationGO:00328802310.026
positive regulation of purine nucleotide catabolic processGO:0033123880.026
peptidyl amino acid modificationGO:00181933360.025
organic hydroxy compound metabolic processGO:19016152030.025
leukocyte differentiationGO:00025213420.025
leukocyte migrationGO:00509001240.025
organophosphate biosynthetic processGO:00904071220.025
cellular chemical homeostasisGO:00550822150.025
axonogenesisGO:00074092740.025
regulation of rho protein signal transductionGO:0035023710.025
anion transportGO:00068201770.025
positive regulation of nervous system developmentGO:00519622210.024
muscle system processGO:00030121410.024
Mouse
regulation of anatomical structure sizeGO:00900661780.024
positive regulation of protein phosphorylationGO:00019342420.024
Mouse
cellular response to lipidGO:00713961450.024
regulation of intracellular transportGO:00323861590.024
carbohydrate metabolic processGO:00059752300.024
organelle localizationGO:00516401790.024
negative regulation of protein modification processGO:00314001630.024
spermatogenesisGO:00072832840.023
circulatory system processGO:00030131970.023
Mouse
regulation of t cell activationGO:00508631700.023
Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.023
negative regulation of phosphorylationGO:00423261660.023
negative regulation of immune system processGO:00026832090.023
Mouse
cation homeostasisGO:00550802120.023
negative regulation of cell developmentGO:00107211690.023
carbohydrate derivative biosynthetic processGO:19011371830.022
organelle fissionGO:00482851700.022
cellular response to organonitrogen compoundGO:00714171450.022
transmission of nerve impulseGO:0019226760.022
mitochondrion organizationGO:00070051340.022
Rat
lipid localizationGO:00108761260.022
angiogenesisGO:00015252010.022
regulation of neuron differentiationGO:00456642810.022
myeloid cell differentiationGO:00300992330.022
regulation of hormone levelsGO:00108172110.022
regulation of system processGO:00440572000.022
Mouse
regulation of neuron projection developmentGO:00109751690.022
macromolecule catabolic processGO:00090572810.022
action potentialGO:0001508780.022
monocarboxylic acid metabolic processGO:00327871910.021
muscle contractionGO:00069361010.021
Mouse
locomotory behaviorGO:00076261950.021
sequestering of metal ionGO:0051238190.021
lipid biosynthetic processGO:00086101790.021
regulation of cytoskeleton organizationGO:00514931220.021
divalent inorganic cation homeostasisGO:00725071380.021
intracellular protein transportGO:00068862040.021
Rat
regulation of cell activationGO:00508652890.021
Mouse
actin filament organizationGO:00070151130.021
skeletal system developmentGO:00015013560.021
inflammatory responseGO:00069542440.021
sensory perceptionGO:00076002450.020
Mouse
single organism cell adhesionGO:00986021560.020
negative regulation of organelle organizationGO:0010639900.020
meiotic cell cycleGO:00513211220.020
regulation of actin filament based processGO:0032970990.020
fat cell differentiationGO:00454441600.020
glycerolipid metabolic processGO:00464861220.020
cellular response to hormone stimulusGO:00328701500.020
regulation of cell cycleGO:00517262810.020
striated muscle tissue developmentGO:00147062930.020
activation of immune responseGO:00022531380.020
telencephalon developmentGO:00215371860.020
regulation of cell morphogenesis involved in differentiationGO:00107691510.020
glucose homeostasisGO:00425931280.020
protein modification by small protein conjugationGO:00324461870.019
positive regulation of programmed cell deathGO:00430682180.019
negative regulation of cellular amino acid metabolic processGO:004576300.019
organic anion transportGO:00157111370.019
regulation of protein transportGO:00512231630.019
lymphocyte proliferationGO:00466511640.019
Mouse
negative regulation of cellular amine metabolic processGO:003323910.019
response to molecule of bacterial originGO:00022371430.019
apoptotic signaling pathwayGO:00971903060.019
response to peptide hormoneGO:00434341270.019
cell type specific apoptotic processGO:00972852680.019
regulation of establishment of protein localizationGO:00702011810.019
regulation of mapk cascadeGO:00434082480.019
Mouse
muscle cell differentiationGO:00426922610.019
positive regulation of organelle organizationGO:00106381280.018
cellular ion homeostasisGO:00068731650.018
protein catabolic processGO:00301632210.018
regulation of muscle system processGO:0090257800.018
Mouse
regulation of response to woundingGO:19030341890.018
nitrogen compound transportGO:00717052710.018
homeostasis of number of cellsGO:00488722100.018
protein localization to membraneGO:00726571080.018
phospholipid metabolic processGO:0006644870.018
regionalizationGO:00030023370.018
protein localization to organelleGO:00333651850.018
Rat
regulation of cell migrationGO:00303342190.018
calcium ion transmembrane transportGO:0070588850.018
metal ion homeostasisGO:00550651890.018
regulation of cytoplasmic transportGO:19036491120.018
positive regulation of apoptotic processGO:00430652170.018
regulation of protein serine threonine kinase activityGO:00719001570.018
Mouse
negative regulation of transferase activityGO:0051348850.018
rab protein signal transductionGO:003248210.017
positive regulation of cell deathGO:00109422240.017
blood vessel morphogenesisGO:00485142850.017
negative regulation of nervous system developmentGO:00519611560.017
sequestering of calcium ionGO:0051208180.017
regulation of metal ion transportGO:00109591060.017
response to insulinGO:00328681000.017
fatty acid metabolic processGO:00066311210.017
neuronal action potentialGO:0019228540.017
multicellular organismal homeostasisGO:00488711640.017
negative regulation of cell projection organizationGO:0031345560.017
posttranscriptional regulation of gene expressionGO:00106081550.017
heart contractionGO:0060047930.017
Mouse
endomembrane system organizationGO:00102561470.017
cell divisionGO:00513011200.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.017
cofactor metabolic processGO:0051186800.016
amide transportGO:00428861380.016
negative regulation of kinase activityGO:0033673810.016
response to lipopolysaccharideGO:00324961280.016
positive regulation of neuron differentiationGO:00456661410.016
protein ubiquitinationGO:00165671710.016
response to radiationGO:00093141650.016
Mouse
lymphocyte differentiationGO:00300982420.016
positive regulation of transferase activityGO:00513471670.016
Mouse
developmental maturationGO:00217001930.016
regulation of body fluid levelsGO:00508781620.016
alcohol metabolic processGO:00060661160.016
calcium ion homeostasisGO:00550741270.016
mitotic cell cycleGO:00002781950.016
regulation of muscle contractionGO:0006937490.016
Mouse
heart morphogenesisGO:00030071780.016
small molecule biosynthetic processGO:00442831320.016
carboxylic acid biosynthetic processGO:0046394860.016
learning or memoryGO:00076111480.016
gland developmentGO:00487323300.016
cellular response to insulin stimulusGO:0032869780.016
cellular carbohydrate metabolic processGO:00442621190.016
camera type eye developmentGO:00430102660.015
Mouse
peptide transportGO:00158331330.015
chemotaxisGO:00069352470.015
cellular metal ion homeostasisGO:00068751510.015
defecationGO:003042110.015
memoryGO:0007613580.015
regulation of transporter activityGO:0032409570.015
cell substrate adhesionGO:00315891300.015
cellular macromolecule catabolic processGO:00442652060.015
protein modification by small protein conjugation or removalGO:00706472070.015
regulation of cell cycle processGO:00105641600.015
myosin filament assemblyGO:003103420.015
wnt signaling pathwayGO:00160551880.015
response to organic cyclic compoundGO:00140701980.015
protein maturationGO:00516041760.015
regulation of proteolysisGO:00301621640.015
myosin filament organizationGO:003103330.015
regulation of feeding behaviorGO:006025930.015
relaxation of muscleGO:0090075180.015
Mouse
cognitionGO:00508901490.015
regulation of cellular component sizeGO:00325351210.014
neuron migrationGO:00017641220.014
response to light stimulusGO:00094161350.014
Mouse
cellular response to lipopolysaccharideGO:0071222770.014
carbohydrate homeostasisGO:00335001280.014
response to peptideGO:19016521360.014
cellular protein complex assemblyGO:00436231160.014
leukocyte chemotaxisGO:0030595690.014
cellular response to biotic stimulusGO:0071216920.014
negative regulation of intracellular signal transductionGO:19025321670.014
cell fate commitmentGO:00451652100.014
positive regulation of cytokine productionGO:00018191740.014
sensory organ morphogenesisGO:00905962420.014
Mouse
positive regulation of secretionGO:00510471300.014
bone developmentGO:00603481200.014
sulfur compound metabolic processGO:00067901000.014
regulation of neuron deathGO:19012141340.014
t cell proliferationGO:00420981200.014
Mouse
regulation of vesicle mediated transportGO:00606271390.014
positive regulation of secretion by cellGO:19035321140.014
heart processGO:0003015940.014
Mouse
dna metabolic processGO:00062593030.014
regulation of cell divisionGO:0051302760.014
small molecule catabolic processGO:0044282710.013
negative regulation of neuron projection developmentGO:0010977500.013
regulation of cellular component biogenesisGO:00440871810.013
protein targetingGO:00066051430.013
Rat
meiotic nuclear divisionGO:00071261150.013
immune response regulating signaling pathwayGO:00027641250.013
cellular response to cytokine stimulusGO:00713451890.013
nuclear transportGO:00511691390.013
glycerophospholipid metabolic processGO:0006650710.013
cardiac muscle contractionGO:0060048320.013
Mouse
generation of precursor metabolites and energyGO:00060911030.013
cellular response to peptideGO:1901653920.013
response to growth factorGO:00708481980.013
negative regulation of lymphocyte activationGO:0051250910.013
Mouse
epithelial cell developmentGO:00020641590.013
Rat
cellular response to organic cyclic compoundGO:0071407870.013
nucleoside phosphate biosynthetic processGO:1901293790.013
spermatid differentiationGO:00485151150.013
regulation of adrenergic receptor signaling pathwayGO:007187740.013
regulation of cellular response to stressGO:00801351590.013
nucleoside monophosphate metabolic processGO:0009123850.013
positive regulation of homeostatic processGO:0032846640.013
b cell activationGO:00421131610.013
lipid catabolic processGO:0016042690.013
hematopoietic progenitor cell differentiationGO:00022441430.013
ossificationGO:00015032160.013
steroid metabolic processGO:00082021190.013
lipid modificationGO:0030258650.013
detection of stimulusGO:0051606840.013
Mouse
positive regulation of neuron projection developmentGO:0010976790.013
organic hydroxy compound transportGO:0015850930.013
retina development in camera type eyeGO:00600411190.013
Mouse
nucleocytoplasmic transportGO:00069131390.013
organic acid biosynthetic processGO:0016053860.013
hormone secretionGO:00468791280.013
reactive oxygen species metabolic processGO:0072593840.013
microtubule based processGO:00070172360.013
mitochondrion distributionGO:004831140.012
regulation of ion homeostasisGO:2000021640.012
t cell differentiationGO:00302171740.012
organic acid transportGO:00158491010.012
monosaccharide transportGO:0015749580.012
anatomical structure homeostasisGO:00602491450.012
developmental growth involved in morphogenesisGO:00605601380.012
regulation of mitotic cell cycleGO:00073461260.012
negative regulation of neuron differentiationGO:00456651010.012
compound eye developmentGO:004874910.012
innate immune responseGO:00450871570.012
inter male aggressive behaviorGO:000212130.012
epithelial cell proliferationGO:00506731740.012
negative regulation of cell activationGO:00508661110.012
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
lipid transportGO:0006869980.012
regulation of cell adhesionGO:00301551540.012
actin filament based movementGO:0030048230.012
thermosensory behaviorGO:004004010.012
nucleotide biosynthetic processGO:0009165780.012
positive regulation of rho gtpase activityGO:0032321410.012
ribose phosphate biosynthetic processGO:0046390590.012
regulation of calcium ion transportGO:0051924690.012
regulation of inflammatory responseGO:00507271470.012
connective tissue developmentGO:00614481790.012
lateral inhibitionGO:004633110.012
erk1 and erk2 cascadeGO:0070371770.012
positive regulation of defense responseGO:00313491240.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
digestive system developmentGO:00551232000.012
regulation of ion transmembrane transporter activityGO:0032412540.012
positive regulation of protein transportGO:0051222930.012
tube formationGO:00351481400.012
mitotic cell cycle processGO:19030471590.012
adult behaviorGO:00305341350.012
pallium developmentGO:00215431200.012
fertilizationGO:00095661270.012
regulation of synaptic growth at neuromuscular junctionGO:000858240.012
single fertilizationGO:0007338820.012
respiratory system developmentGO:00605411900.012
asymmetric stem cell divisionGO:009872230.012
carboxylic acid transportGO:00469421000.012
axon guidanceGO:00074111410.012
retrograde transport endosome to golgiGO:004214720.012
glycoprotein biosynthetic processGO:0009101890.012
second messenger mediated signalingGO:0019932730.012
neuron neuron synaptic transmissionGO:0007270690.012
single organismal cell cell adhesionGO:00163371310.012
germ cell developmentGO:00072811850.012
Mouse
peptidyl serine phosphorylationGO:0018105740.011
chromatin organizationGO:00063252060.011
skeletal muscle organ developmentGO:00605381630.011
regulation of blood circulationGO:1903522930.011
Mouse
positive regulation of response to woundingGO:1903036660.011
response to acid chemicalGO:00011011110.011
response to inorganic substanceGO:0010035960.011
cellular response to dna damage stimulusGO:00069742070.011
establishment of protein localization to organelleGO:00725941180.011
Rat
regulation of lipid metabolic processGO:00192161180.011
cellular response to peptide hormone stimulusGO:0071375920.011
regulation of leukocyte differentiationGO:19021051590.011
neuron deathGO:00709971540.011
regulation of apoptotic signaling pathwayGO:20012331970.011
adult locomotory behaviorGO:0008344910.011
regulation of engulfment of apoptotic cellGO:190107420.011
plasma membrane organizationGO:0007009900.011
hexose transportGO:0008645560.011
organic hydroxy compound biosynthetic processGO:1901617770.011
cellular component assembly involved in morphogenesisGO:00109271390.011
coenzyme metabolic processGO:0006732520.011
epithelial tube morphogenesisGO:00605623030.011
phosphatidylinositol metabolic processGO:0046488450.011
b cell differentiationGO:0030183780.011
regulation of neurotransmitter levelsGO:0001505870.011
positive regulation of mapk cascadeGO:00434101700.011
Mouse
glycoprotein metabolic processGO:00091001160.011
positive regulation of protein kinase activityGO:00458601440.011
Mouse
cardiac muscle cell contractionGO:008600370.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
response to oxidative stressGO:00069791230.011
immune response activating signal transductionGO:00027571160.011
transforming growth factor beta receptor signaling pathwayGO:0007179710.011
striated muscle myosin thick filament assemblyGO:007168810.011
purine nucleoside monophosphate metabolic processGO:0009126810.011
positive regulation of protein export from nucleusGO:004682740.011
energy derivation by oxidation of organic compoundsGO:0015980770.011
regulation of behavioral fear responseGO:200082220.011
positive regulation of kinase activityGO:00336741550.011
Mouse
positive regulation of rap gtpase activityGO:003285430.011
engulfment of apoptotic cellGO:004365230.011
regulation of voltage gated calcium channel activityGO:190138540.011
monosaccharide metabolic processGO:00059961060.011
inclusion body assemblyGO:007084130.011
cell activation involved in immune responseGO:00022631260.011
regulation of rho gtpase activityGO:0032319580.011
regulation of epithelial cell proliferationGO:00506781410.011
regulation of synaptic plasticityGO:0048167870.010
leukocyte mediated immunityGO:00024431740.010
rhythmic processGO:00485111740.010
myotube differentiationGO:00149021050.010
cellular response to growth factor stimulusGO:00713631970.010
carbohydrate biosynthetic processGO:0016051740.010
peptide secretionGO:00027901140.010
rac protein signal transductionGO:0016601130.010
lipid homeostasisGO:0055088630.010
protein autophosphorylationGO:0046777610.010
regulation of actin cytoskeleton organizationGO:0032956840.010
extracellular structure organizationGO:00430621480.010
central nervous system neuron differentiationGO:00219531620.010
myeloid cell homeostasisGO:00022621140.010
peptide hormone secretionGO:00300721090.010
regulation of endopeptidase activityGO:0052548890.010
regulation of angiogenesisGO:0045765810.010
reactive nitrogen species metabolic processGO:200105700.010
detection of abiotic stimulusGO:0009582600.010
Mouse
actin polymerization or depolymerizationGO:0008154540.010
positive regulation of protein serine threonine kinase activityGO:00719021060.010
Mouse
protein processingGO:00164851630.010
midgut developmentGO:000749440.010
regulation of hormone secretionGO:0046883880.010

Pde2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.027
nervous system diseaseDOID:86300.027
disease of metabolismDOID:001466700.020
inherited metabolic disorderDOID:65500.014
immune system diseaseDOID:291400.013
central nervous system diseaseDOID:33100.013
hematopoietic system diseaseDOID:7400.011
musculoskeletal system diseaseDOID:1700.011