Mus musculus

0 known processes

Akr1b7

aldo-keto reductase family 1, member B7

(Aliases: MVDP,AR,Avdp,MGC107658)

Akr1b7 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143420.254
Mouse
response to organonitrogen compoundGO:00102432460.179
cellular ketone metabolic processGO:0042180840.107
Mouse
lipid biosynthetic processGO:00086101790.107
amine metabolic processGO:0009308450.092
cellular amino acid metabolic processGO:00065201030.083
response to organic cyclic compoundGO:00140701980.082
fatty acid metabolic processGO:00066311210.081
monocarboxylic acid metabolic processGO:00327871910.072
Mouse
cellular amine metabolic processGO:0044106440.069
cellular lipid metabolic processGO:00442553230.069
regulation of cellular ketone metabolic processGO:0010565660.069
steroid metabolic processGO:00082021190.068
Mouse
lipid homeostasisGO:0055088630.066
transmembrane transportGO:00550854120.061
response to acid chemicalGO:00011011110.057
cholesterol homeostasisGO:0042632440.056
generation of precursor metabolites and energyGO:00060911030.056
regulation of t cell activationGO:00508631700.056
negative regulation of phosphorylationGO:00423261660.055
cofactor metabolic processGO:0051186800.055
regulation of cytokine productionGO:00018172660.053
sterol homeostasisGO:0055092450.053
maintenance of locationGO:0051235890.052
negative regulation of protein metabolic processGO:00512482820.051
cellular homeostasisGO:00197252400.051
gland developmentGO:00487323300.050
nitrogen compound transportGO:00717052710.050
negative regulation of molecular functionGO:00440922580.050
regulation of lymphocyte activationGO:00512492400.049
regulation of secretion by cellGO:19035302490.049
fertilizationGO:00095661270.048
cytokine productionGO:00018163190.047
response to amino acidGO:0043200370.046
cellular response to acid chemicalGO:0071229680.046
drug metabolic processGO:001714440.045
regulation of cellular amine metabolic processGO:0033238200.044
organic hydroxy compound metabolic processGO:19016152030.044
xenobiotic catabolic processGO:004217810.044
cellular response to organonitrogen compoundGO:00714171450.042
energy derivation by oxidation of organic compoundsGO:0015980770.042
negative regulation of phosphate metabolic processGO:00459361840.040
inflammatory responseGO:00069542440.040
ion transmembrane transportGO:00342203610.040
cation transportGO:00068123990.040
carbohydrate metabolic processGO:00059752300.040
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.039
immune effector processGO:00022523210.038
innate immune responseGO:00450871570.038
regulation of protein localizationGO:00328802310.037
hexose metabolic processGO:0019318980.037
regulation of leukocyte differentiationGO:19021051590.036
organic acid transportGO:00158491010.036
g protein coupled receptor signaling pathwayGO:00071862430.036
protein modification by small protein conjugationGO:00324461870.036
cellular response to peptide hormone stimulusGO:0071375920.035
protein modification by small protein conjugation or removalGO:00706472070.035
lipid localizationGO:00108761260.034
cellular response to amino acid stimulusGO:0071230290.034
adaptive immune responseGO:00022501550.034
glucose metabolic processGO:0006006920.033
regulation of hydrolase activityGO:00513362460.033
macromolecule catabolic processGO:00090572810.033
cellular response to insulin stimulusGO:0032869780.033
negative regulation of phosphorus metabolic processGO:00105631840.032
homeostasis of number of cellsGO:00488722100.031
negative regulation of cellular amino acid metabolic processGO:004576300.031
anion transportGO:00068201770.031
positive regulation of secretionGO:00510471300.030
apoptotic signaling pathwayGO:00971903060.030
cellular response to peptideGO:1901653920.030
fat soluble vitamin biosynthetic processGO:004236240.029
regulation of cell activationGO:00508652890.029
regulation of secretionGO:00510462740.029
cellular ion homeostasisGO:00068731650.029
alcohol metabolic processGO:00060661160.029
regulation of cellular amino acid metabolic processGO:000652150.029
reactive oxygen species metabolic processGO:0072593840.029
dephosphorylationGO:00163111290.028
positive regulation of programmed cell deathGO:00430682180.028
secondary alcohol metabolic processGO:190265230.028
negative regulation of intracellular signal transductionGO:19025321670.027
cellular response to cadmium ionGO:007127630.027
regulation of defense responseGO:00313472330.027
cell type specific apoptotic processGO:00972852680.027
spermatogenesisGO:00072832840.027
hormone metabolic processGO:0042445860.027
Mouse
response to extracellular stimulusGO:00099911270.027
leukocyte differentiationGO:00025213420.027
leukocyte activation involved in immune responseGO:00023661260.027
organonitrogen compound catabolic processGO:19015652640.027
t cell activationGO:00421102890.026
lipid storageGO:0019915360.026
nucleobase containing small molecule metabolic processGO:00550863520.026
negative regulation of immune system processGO:00026832090.026
positive regulation of cell deathGO:00109422240.026
regulation of cell motilityGO:20001452360.026
purine containing compound metabolic processGO:00725213110.026
response to peptide hormoneGO:00434341270.026
protein processingGO:00164851630.026
regulation of homeostatic processGO:00328441820.026
regulation of reactive oxygen species metabolic processGO:2000377400.026
positive regulation of cellular amine metabolic processGO:003324050.026
response to nutrient levelsGO:00316671090.026
cellular chemical homeostasisGO:00550822150.025
metal ion homeostasisGO:00550651890.025
multicellular organism growthGO:00352641610.025
cellular response to hormone stimulusGO:00328701500.025
response to peptideGO:19016521360.025
cellular response to lipidGO:00713961450.025
lipid transportGO:0006869980.025
negative regulation of protein phosphorylationGO:00019331260.025
cation homeostasisGO:00550802120.025
cellular macromolecule catabolic processGO:00442652060.024
heterocycle catabolic processGO:00467002800.024
vitamin d biosynthetic processGO:004236830.024
sulfur compound metabolic processGO:00067901000.024
regulation of transferase activityGO:00513382630.024
regulation of hormone levelsGO:00108172110.024
Mouse
cytokine mediated signaling pathwayGO:00192211150.023
sequestering of calcium ionGO:0051208180.023
positive regulation of apoptotic processGO:00430652170.023
glucose homeostasisGO:00425931280.023
defense response to other organismGO:00985421970.023
cellular alcohol biosynthetic processGO:004410830.023
reactive nitrogen species metabolic processGO:200105700.023
protein ubiquitinationGO:00165671710.023
organophosphate biosynthetic processGO:00904071220.022
regulation of inflammatory responseGO:00507271470.022
nucleotide metabolic processGO:00091173320.022
regulation of ion transportGO:00432692150.022
energy reserve metabolic processGO:0006112390.022
peptide transportGO:00158331330.022
positive regulation of t cell activationGO:00508701010.022
positive regulation of cytokine productionGO:00018191740.022
small molecule biosynthetic processGO:00442831320.022
Mouse
carbohydrate transportGO:0008643620.022
regulation of kinase activityGO:00435492490.022
alpha amino acid metabolic processGO:1901605590.021
calcitriol biosynthetic process from calciolGO:003637830.021
cell adhesionGO:00071553290.021
negative regulation of cell proliferationGO:00082852960.021
germ cell developmentGO:00072811850.021
negative regulation of immune effector processGO:0002698550.021
positive regulation of defense responseGO:00313491240.021
positive regulation of nervous system developmentGO:00519622210.021
organic anion transportGO:00157111370.020
regulation of lymphocyte differentiationGO:00456191070.020
negative regulation of protein modification processGO:00314001630.020
myeloid cell differentiationGO:00300992330.020
organic cyclic compound catabolic processGO:19013612950.020
Mouse
fat cell differentiationGO:00454441600.020
placenta developmentGO:00018901400.020
male gamete generationGO:00482322850.020
response to oxidative stressGO:00069791230.020
response to inorganic substanceGO:0010035960.020
defense response to bacteriumGO:00427421190.020
hexose transportGO:0008645560.020
drug catabolic processGO:004273720.020
progesterone metabolic processGO:004244840.020
Mouse
regulation of cell migrationGO:00303342190.020
response to molecule of bacterial originGO:00022371430.020
regulation of membrane potentialGO:00423911920.019
regulation of protein serine threonine kinase activityGO:00719001570.019
respiratory system developmentGO:00605411900.019
leukocyte proliferationGO:00706611720.019
cellular metal ion homeostasisGO:00068751510.019
small gtpase mediated signal transductionGO:0007264970.019
cellular carbohydrate metabolic processGO:00442621190.019
learning or memoryGO:00076111480.019
positive regulation of neuron differentiationGO:00456661410.019
carboxylic acid transportGO:00469421000.019
negative regulation of transferase activityGO:0051348850.019
blood coagulationGO:0007596760.019
regulation of organelle organizationGO:00330432890.019
regulation of cellular component biogenesisGO:00440871810.019
negative regulation of cellular amine metabolic processGO:003323910.019
isoprenoid metabolic processGO:0006720290.019
inorganic ion transmembrane transportGO:00986602340.019
lung developmentGO:00303241640.019
regulation of response to woundingGO:19030341890.018
regulation of proteolysisGO:00301621640.018
monosaccharide metabolic processGO:00059961060.018
Mouse
regulation of body fluid levelsGO:00508781620.018
organonitrogen compound biosynthetic processGO:19015661920.018
positive regulation of leukocyte differentiationGO:1902107860.018
membrane organizationGO:00610242450.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.018
cellular alcohol metabolic processGO:004410730.018
amide transportGO:00428861380.018
glycoprotein metabolic processGO:00091001160.018
carboxylic acid biosynthetic processGO:0046394860.018
Mouse
cellular protein catabolic processGO:00442571550.018
negative regulation of cellular component organizationGO:00511291940.018
monosaccharide transportGO:0015749580.017
aromatic compound catabolic processGO:00194392860.017
protein secretionGO:00093061110.017
lipid modificationGO:0030258650.017
ribonucleotide metabolic processGO:00092592910.017
lymphocyte activation involved in immune responseGO:0002285930.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
cell activation involved in immune responseGO:00022631260.017
regulation of mapk cascadeGO:00434082480.017
lymphocyte differentiationGO:00300982420.017
organelle assemblyGO:00709251770.017
t cell activation involved in immune responseGO:0002286430.017
positive regulation of lymphocyte activationGO:00512511400.017
exocytosisGO:00068871210.017
protein catabolic processGO:00301632210.017
blood vessel morphogenesisGO:00485142850.017
cell substrate adhesionGO:00315891300.017
proteolysis involved in cellular protein catabolic processGO:00516031470.017
sequestering of metal ionGO:0051238190.017
response to insulinGO:00328681000.017
negative regulation of kinase activityGO:0033673810.017
regulation of activation of jak2 kinase activityGO:001053410.017
regulation of vesicle mediated transportGO:00606271390.017
oligopeptide transmembrane transportGO:003567240.017
small molecule catabolic processGO:0044282710.017
Mouse
insulin receptor signaling pathwayGO:0008286490.016
negative regulation of t helper 2 cell differentiationGO:004562940.016
reactive oxygen species biosynthetic processGO:190340980.016
multicellular organismal homeostasisGO:00488711640.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.016
cellular amide metabolic processGO:0043603580.016
diterpenoid metabolic processGO:0016101240.016
regulation of activation of janus kinase activityGO:001053310.016
carbohydrate derivative biosynthetic processGO:19011371830.016
phospholipid metabolic processGO:0006644870.016
negative regulation of lymphocyte activationGO:0051250910.016
purine nucleotide metabolic processGO:00061633020.016
regulation of glucose metabolic processGO:0010906600.016
response to oxygen levelsGO:0070482620.016
macromolecule methylationGO:00434141200.016
negative regulation of cell activationGO:00508661110.016
cellular response to biotic stimulusGO:0071216920.016
exogenous drug catabolic processGO:004273810.016
circulatory system processGO:00030131970.015
regulation of innate immune responseGO:0045088910.015
regulation of myeloid cell differentiationGO:0045637960.015
peptidyl amino acid modificationGO:00181933360.015
response to radiationGO:00093141650.015
cellular nitrogen compound catabolic processGO:00442702800.015
glucose transportGO:0015758560.015
cd4 positive alpha beta t cell activationGO:0035710450.015
blood circulationGO:00080151950.015
alpha beta t cell activationGO:0046631910.015
positive regulation of protein modification processGO:00314012990.015
t cell differentiationGO:00302171740.015
sulfate assimilationGO:000010330.015
negative regulation of hydrolase activityGO:0051346710.015
establishment of organelle localizationGO:00516561220.015
regulation of phospholipid biosynthetic processGO:007107130.015
regulation of t cell differentiationGO:0045580830.015
cation transmembrane transportGO:00986552660.015
morphogenesis of a branching epitheliumGO:00611381930.015
regulation of neuron differentiationGO:00456642810.015
carbohydrate biosynthetic processGO:0016051740.015
Mouse
engulfment of apoptotic cellGO:004365230.015
ras protein signal transductionGO:0007265770.015
alpha beta t cell differentiationGO:0046632690.015
positive regulation of cell activationGO:00508671580.015
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.014
positive regulation of secretion by cellGO:19035321140.014
protein maturationGO:00516041760.014
regulation of establishment of protein localizationGO:00702011810.014
jak stat cascadeGO:0007259420.014
vitamin d3 metabolic processGO:007064030.014
response to drugGO:0042493750.014
membrane lipid metabolic processGO:0006643530.014
fatty acid derivative metabolic processGO:1901568330.014
cellular response to oxidative stressGO:0034599760.014
cellular calcium ion homeostasisGO:00068741190.014
actin cytoskeleton organizationGO:00300362200.014
urogenital system developmentGO:00016552610.014
regulation of lymphocyte proliferationGO:00506701170.014
regulation of carbohydrate metabolic processGO:0006109750.014
lipoprotein metabolic processGO:0042157430.014
negative regulation of protein processingGO:0010955790.014
sensory perceptionGO:00076002450.014
purine ribonucleotide metabolic processGO:00091502900.014
response to lipopolysaccharideGO:00324961280.014
alcohol biosynthetic processGO:0046165430.014
unsaturated fatty acid metabolic processGO:0033559310.014
regulation of cell projection organizationGO:00313442060.014
glutathione metabolic processGO:0006749160.014
glycosyl compound metabolic processGO:19016572460.014
regulation of leukocyte proliferationGO:00706631210.014
glycerophospholipid metabolic processGO:0006650710.013
response to vitamin aGO:003318910.013
regulation of anatomical structure sizeGO:00900661780.013
organic hydroxy compound biosynthetic processGO:1901617770.013
regulation of phospholipase a2 activityGO:003242930.013
methylationGO:00322591340.013
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.013
inorganic cation transmembrane transportGO:00986622070.013
purine nucleotide catabolic processGO:00061952110.013
purine nucleoside catabolic processGO:00061522050.013
cellular glucan metabolic processGO:0006073320.013
negative regulation of defense responseGO:0031348770.013
ribonucleoside metabolic processGO:00091192450.013
organelle localizationGO:00516401790.013
negative regulation of leukocyte differentiationGO:1902106510.013
locomotory behaviorGO:00076261950.013
amino acid transmembrane transportGO:0003333370.013
vesicle localizationGO:0051648860.013
regulation of apoptotic signaling pathwayGO:20012331970.013
establishment of vesicle localizationGO:0051650810.013
hormone secretionGO:00468791280.013
leukocyte migrationGO:00509001240.013
erk1 and erk2 cascadeGO:0070371770.013
divalent inorganic cation transportGO:00725111780.013
single organism cell adhesionGO:00986021560.013
cognitionGO:00508901490.013
regulation of protein transportGO:00512231630.013
positive regulation of immune effector processGO:00026991070.013
modification dependent macromolecule catabolic processGO:00436321330.013
forebrain developmentGO:00309003020.013
nucleoside metabolic processGO:00091162460.013
purine nucleoside metabolic processGO:00422782410.012
regulation of sequence specific dna binding transcription factor activityGO:00510901060.012
regulation of carbohydrate biosynthetic processGO:0043255400.012
positive regulation of cellular amino acid metabolic processGO:004576430.012
regulation of multi organism processGO:00439001110.012
divalent metal ion transportGO:00708381720.012
retinoic acid metabolic processGO:0042573120.012
nucleoside phosphate catabolic processGO:19012922220.012
nucleotide catabolic processGO:00091662170.012
medium chain fatty acid metabolic processGO:005179110.012
purine nucleoside triphosphate metabolic processGO:00091442260.012
positive regulation of reactive oxygen species metabolic processGO:2000379110.012
regulation of protein secretionGO:0050708820.012
regulation of cellular carbohydrate metabolic processGO:0010675750.012
steroid biosynthetic processGO:0006694470.012
positive regulation of organelle organizationGO:00106381280.012
myeloid cell homeostasisGO:00022621140.012
positive regulation of cell developmentGO:00107202370.012
carboxylic acid catabolic processGO:0046395510.012
Mouse
calcium ion homeostasisGO:00550741270.012
nucleoside phosphate metabolic processGO:00067533380.012
cellular response to dna damage stimulusGO:00069742070.012
nucleoside catabolic processGO:00091642060.012
negative regulation of cellular response to insulin stimulusGO:1900077160.012
cellular response to extracellular stimulusGO:0031668810.012
regulation of leukocyte mediated cytotoxicityGO:0001910380.012
positive regulation of protein phosphorylationGO:00019342420.012
terpenoid metabolic processGO:0006721250.012
camera type eye developmentGO:00430102660.012
dna metabolic processGO:00062593030.012
nucleoside triphosphate catabolic processGO:00091432050.012
glycerolipid biosynthetic processGO:0045017500.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
lipid catabolic processGO:0016042690.012
Mouse
regulation of protein kinase activityGO:00458592320.012
purine ribonucleoside metabolic processGO:00461282410.012
cell junction assemblyGO:0034329520.012
positive regulation of mapk cascadeGO:00434101700.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
leukocyte mediated immunityGO:00024431740.012
fatty acid oxidationGO:0019395280.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
regulation of cellular catabolic processGO:00313292420.011
amino acid transportGO:0006865610.011
positive regulation of growthGO:00459271040.011
myeloid leukocyte differentiationGO:00025731190.011
renal system developmentGO:00720012250.011
microglia developmentGO:001400520.011
pigment granule localizationGO:0051875130.011
rho protein signal transductionGO:0007266320.011
mitochondrion organizationGO:00070051340.011
activation of immune responseGO:00022531380.011
circadian regulation of gene expressionGO:0032922480.011
b cell activationGO:00421131610.011
regulation of gluconeogenesisGO:0006111300.011
primary alcohol metabolic processGO:0034308110.011
cellular response to lipopolysaccharideGO:0071222770.011
response to xenobiotic stimulusGO:0009410130.011
spermatid differentiationGO:00485151150.011
multicellular organismal signalingGO:0035637910.011
activation of janus kinase activityGO:004297620.011
modification dependent protein catabolic processGO:00199411330.011
negative regulation of t cell activationGO:0050868650.011
hexose biosynthetic processGO:0019319390.011
organic acid catabolic processGO:0016054510.011
Mouse
mitotic cell cycleGO:00002781950.011
cellular response to nutrient levelsGO:0031669640.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
cd4 positive alpha beta t cell differentiationGO:0043367410.011
purine ribonucleotide catabolic processGO:00091542080.011
tissue remodelingGO:00487711020.011
response to steroid hormoneGO:0048545560.011
mapk cascadeGO:00001652810.011
female gamete generationGO:0007292740.011
transmission of nerve impulseGO:0019226760.011
retrograde transport endosome to golgiGO:004214720.011
regulation of chloride transportGO:200122520.011
action potentialGO:0001508780.011
cellular protein complex assemblyGO:00436231160.011
negative regulation of cell migrationGO:0030336590.011
peptide secretionGO:00027901140.011
regulation of peptide transportGO:0090087910.011
glycerophospholipid biosynthetic processGO:0046474320.011
development of primary sexual characteristicsGO:00451371430.011
calcium ion transportGO:00068161590.011
cytosolic calcium ion homeostasisGO:0051480700.011
divalent inorganic cation homeostasisGO:00725071380.011
body fluid secretionGO:0007589530.011
tissue homeostasisGO:00018941150.011
single organismal cell cell adhesionGO:00163371310.011
negative regulation of homeostatic processGO:0032845710.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
cytokine metabolic processGO:0042107710.011
ribose phosphate metabolic processGO:00196932910.011
long chain fatty acid metabolic processGO:0001676260.011
positive regulation of transferase activityGO:00513471670.010
c21 steroid hormone biosynthetic processGO:000670030.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.010
multi multicellular organism processGO:00447061090.010
Mouse
endocytosisGO:00068971680.010
peptidyl tyrosine modificationGO:00182121450.010
regulation of alpha beta t cell differentiationGO:0046637350.010
negative regulation of mapk cascadeGO:0043409650.010
cellular aldehyde metabolic processGO:0006081120.010
Mouse
glycerolipid metabolic processGO:00464861220.010
cell killingGO:0001906670.010
organic hydroxy compound transportGO:0015850930.010
layer formation in cerebral cortexGO:0021819130.010
positive regulation of phospholipase activityGO:001051830.010
purine containing compound catabolic processGO:00725232130.010
response to metal ionGO:0010038470.010
neuronal action potentialGO:0019228540.010
negative regulation of chemokine productionGO:003268240.010
nuclear divisionGO:00002801580.010
morphogenesis of a branching structureGO:00017632030.010
negative regulation of cytokine productionGO:0001818840.010
second messenger mediated signalingGO:0019932730.010
cellular modified amino acid metabolic processGO:0006575630.010
peptide hormone secretionGO:00300721090.010
glycosyl compound catabolic processGO:19016582060.010
regulation of vasculature developmentGO:1901342880.010

Akr1b7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.037
disease of anatomical entityDOID:700.037
disease of metabolismDOID:001466700.028
inherited metabolic disorderDOID:65500.021
nervous system diseaseDOID:86300.018
hematopoietic system diseaseDOID:7400.017
sensory system diseaseDOID:005015500.013
retinal degenerationDOID:846600.011
retinal diseaseDOID:567900.011
eye and adnexa diseaseDOID:149200.011
eye diseaseDOID:561400.011
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.011
musculoskeletal system diseaseDOID:1700.011
connective tissue diseaseDOID:6500.011