Mus musculus

66 known processes

Drosha

drosha, ribonuclease type III

(Aliases: MGC115770,1110013A17Rik,AI874853,Etohi2,Rn3,Rnasen)

Drosha biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pre mirna processingGO:003105430.236
gene silencing by mirnaGO:0035195100.175
olfactory learningGO:000835520.170
heterocycle catabolic processGO:00467002800.168
positive regulation of gene silencing by mirnaGO:200063710.167
cellular nitrogen compound catabolic processGO:00442702800.159
aromatic compound catabolic processGO:00194392860.150
cellular macromolecule catabolic processGO:00442652060.144
organic cyclic compound catabolic processGO:19013612950.125
gene silencing by rnaGO:0031047190.105
cellular component assembly involved in morphogenesisGO:00109271390.099
microtubule based processGO:00070172360.084
rna processingGO:00063961050.080
macromolecule catabolic processGO:00090572810.073
posttranscriptional gene silencingGO:0016441100.072
dna catabolic process endonucleolyticGO:0000737150.068
muscle tissue developmentGO:00605373080.060
striated muscle tissue developmentGO:00147062930.060
mirna metabolic processGO:0010586100.060
negative regulation of glial cell proliferationGO:006025340.059
hair follicle cell proliferationGO:007133530.059
myoblast differentiation involved in skeletal muscle regenerationGO:001483530.057
muscle cell differentiationGO:00426922610.054
rna interferenceGO:001624620.052
mrna processingGO:0006397630.052
purine nucleotide metabolic processGO:00061633020.052
nucleotide catabolic processGO:00091662170.051
cellularizationGO:000734910.050
organelle fissionGO:00482851700.049
positive regulation of myelinationGO:003164350.049
glycosyl compound metabolic processGO:19016572460.048
nucleoside phosphate metabolic processGO:00067533380.048
defense response to other organismGO:00985421970.048
Human
production of mirnas involved in gene silencing by mirnaGO:003519660.046
mrna metabolic processGO:0016071840.046
meiotic nuclear divisionGO:00071261150.046
nuclear divisionGO:00002801580.046
telencephalon developmentGO:00215371860.045
nucleobase containing small molecule metabolic processGO:00550863520.045
activation of immune responseGO:00022531380.045
muscle cell developmentGO:00550011330.043
nucleotide metabolic processGO:00091173320.042
ncrna processingGO:0034470260.042
nucleic acid phosphodiester bond hydrolysisGO:0090305490.041
posttranscriptional regulation of gene expressionGO:00106081550.040
spermatogenesisGO:00072832840.040
organophosphate catabolic processGO:00464342320.040
transmission of nerve impulseGO:0019226760.040
regulation of cellular amino acid metabolic processGO:000652150.039
ribonucleoside metabolic processGO:00091192450.039
skeletal system developmentGO:00015013560.039
microtubule cytoskeleton organizationGO:00002261570.038
stem cell differentiationGO:00488632680.038
negative regulation of nervous system developmentGO:00519611560.037
purine ribonucleoside catabolic processGO:00461302050.037
regulation of cellular ketone metabolic processGO:0010565660.037
meiotic cell cycleGO:00513211220.037
purine containing compound catabolic processGO:00725232130.037
multicellular organismal signalingGO:0035637910.037
learningGO:0007612980.036
nucleoside metabolic processGO:00091162460.036
purine ribonucleoside metabolic processGO:00461282410.035
nitrogen compound transportGO:00717052710.035
purine ribonucleotide metabolic processGO:00091502900.035
cation transportGO:00068123990.035
positive regulation of posttranscriptional gene silencingGO:006014810.035
carbohydrate derivative catabolic processGO:19011362310.034
regulation of schwann cell proliferationGO:001062420.034
purine containing compound metabolic processGO:00725213110.034
meiotic cell cycle processGO:1903046770.034
ribose phosphate metabolic processGO:00196932910.034
forebrain developmentGO:00309003020.034
blood vessel morphogenesisGO:00485142850.034
nucleoside phosphate catabolic processGO:19012922220.034
purine nucleoside metabolic processGO:00422782410.033
dna catabolic processGO:0006308190.033
cellular amino acid metabolic processGO:00065201030.033
cytokine productionGO:00018163190.033
negative regulation of cell developmentGO:00107211690.032
regulation of cytokine productionGO:00018172660.032
ribonucleotide catabolic processGO:00092612080.032
cell divisionGO:00513011200.032
male gamete generationGO:00482322850.032
regionalizationGO:00030023370.031
ventricular system developmentGO:0021591270.031
glycosyl compound catabolic processGO:19016582060.031
cognitionGO:00508901490.031
purine nucleoside triphosphate catabolic processGO:00091462030.031
innate immune responseGO:00450871570.030
nucleoside triphosphate metabolic processGO:00091412300.030
regulation of cell cycleGO:00517262810.030
rna phosphodiester bond hydrolysisGO:0090501190.030
schwann cell proliferationGO:001401020.030
dendrite developmentGO:00163581150.030
neuronal action potentialGO:0019228540.030
ribonucleoside triphosphate catabolic processGO:00092031990.030
immune effector processGO:00022523210.030
mechanoreceptor differentiationGO:0042490670.029
regulation of multi organism processGO:00439001110.029
membrane organizationGO:00610242450.029
purine ribonucleotide catabolic processGO:00091542080.029
carbohydrate derivative biosynthetic processGO:19011371830.029
production of small rna involved in gene silencing by rnaGO:007091860.029
positive regulation of innate immune responseGO:0045089800.029
response to organonitrogen compoundGO:00102432460.029
olfactory bulb developmentGO:0021772300.028
regulation of synaptic growth at neuromuscular junctionGO:000858240.028
regulation of organelle organizationGO:00330432890.028
ribonucleotide metabolic processGO:00092592910.028
negative regulation of immune system processGO:00026832090.028
angiogenesisGO:00015252010.028
morphogenesis of a branching epitheliumGO:00611381930.027
ear developmentGO:00435832000.027
negative regulation of intracellular signal transductionGO:19025321670.027
cytoplasmic pattern recognition receptor signaling pathway in response to virusGO:003952840.027
ribonucleoside catabolic processGO:00424542060.026
nerve developmentGO:0021675670.026
nucleoside triphosphate catabolic processGO:00091432050.026
wound healingGO:00420601570.026
learning or memoryGO:00076111480.026
central nervous system neuron differentiationGO:00219531620.026
multicellular organism growthGO:00352641610.025
purine ribonucleoside triphosphate metabolic processGO:00092052200.025
intracellular receptor signaling pathwayGO:0030522740.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
regulation of neuron differentiationGO:00456642810.025
skin developmentGO:00435882200.025
nucleoside catabolic processGO:00091642060.025
purine nucleotide catabolic processGO:00061952110.024
small gtpase mediated signal transductionGO:0007264970.024
purine ribonucleoside triphosphate catabolic processGO:00092071990.024
axonogenesisGO:00074092740.024
ras protein signal transductionGO:0007265770.024
epithelial cell developmentGO:00020641590.024
purine nucleoside catabolic processGO:00061522050.024
axon ensheathmentGO:0008366760.024
nucleobase containing compound transportGO:0015931270.024
modification dependent macromolecule catabolic processGO:00436321330.023
positive regulation of immune effector processGO:00026991070.023
germ cell developmentGO:00072811850.023
ventral spinal cord developmentGO:0021517480.023
positive regulation of defense responseGO:00313491240.023
cell type specific apoptotic processGO:00972852680.023
ribonucleoside triphosphate metabolic processGO:00091992200.023
apoptotic signaling pathwayGO:00971903060.023
cellular divalent inorganic cation homeostasisGO:00725031270.023
cardiac muscle tissue developmentGO:00487381300.023
mitotic cell cycle processGO:19030471590.022
hematopoietic progenitor cell differentiationGO:00022441430.022
protein maturationGO:00516041760.022
positive regulation of cytokine productionGO:00018191740.022
regulation of defense responseGO:00313472330.022
positive regulation of cell developmentGO:00107202370.022
stem cell maintenanceGO:00198271300.022
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.022
cation transmembrane transportGO:00986552660.022
action potentialGO:0001508780.022
regulation of cellular amine metabolic processGO:0033238200.022
heart morphogenesisGO:00030071780.022
dsrna fragmentationGO:003105060.022
cellular homeostasisGO:00197252400.021
protein processingGO:00164851630.021
transmembrane transportGO:00550854120.021
epidermis developmentGO:00085441870.021
myoblast differentiationGO:0045445520.021
positive regulation of cellular amine metabolic processGO:003324050.021
spinal cord developmentGO:0021510810.021
negative regulation of multi organism processGO:0043901680.021
chromosome segregationGO:0007059480.021
positive regulation of nucleoside metabolic processGO:0045979910.021
cerebral cortex developmentGO:0021987860.020
dephosphorylationGO:00163111290.020
skeletal muscle organ developmentGO:00605381630.020
cilium assemblyGO:0042384810.020
regulation of hydrolase activityGO:00513362460.020
organonitrogen compound catabolic processGO:19015652640.020
striated muscle cell developmentGO:00550021250.020
epithelial tube morphogenesisGO:00605623030.020
positive regulation of nucleotide metabolic processGO:00459811140.020
response to starvationGO:0042594650.020
myelination in peripheral nervous systemGO:0022011190.020
cardiac muscle cell differentiationGO:0055007690.020
microtubule based movementGO:0007018840.020
cilium morphogenesisGO:00602711020.020
regulation of secretion by cellGO:19035302490.019
gonad morphogenesisGO:003526210.019
rna phosphodiester bond hydrolysis endonucleolyticGO:0090502100.019
regulation of cellular catabolic processGO:00313292420.019
immune response activating signal transductionGO:00027571160.019
positive regulation of protein modification processGO:00314012990.019
negative regulation of synapse assemblyGO:005196430.019
cellular response to dna damage stimulusGO:00069742070.019
regulation of purine nucleotide catabolic processGO:00331211220.019
cellular response to hormone stimulusGO:00328701500.019
protein ubiquitinationGO:00165671710.019
rho protein signal transductionGO:0007266320.019
intracellular protein transportGO:00068862040.019
cytoplasmic transportGO:00164822340.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.019
gene silencingGO:0016458380.019
nucleic acid transportGO:0050657180.019
morphogenesis of a branching structureGO:00017632030.018
response to radiationGO:00093141650.018
associative learningGO:0008306610.018
myelinationGO:0042552740.018
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.018
cellular response to organonitrogen compoundGO:00714171450.018
positive regulation of gliogenesisGO:0014015270.018
respiratory system developmentGO:00605411900.018
dna metabolic processGO:00062593030.018
organelle assemblyGO:00709251770.018
cartilage developmentGO:00512161400.018
actin cytoskeleton organizationGO:00300362200.018
spinal cord motor neuron differentiationGO:0021522350.018
mapk cascadeGO:00001652810.018
guanosine containing compound catabolic processGO:19010691440.018
circadian rhythmGO:00076231140.018
peripheral nervous system developmentGO:0007422530.018
regulation of cell migrationGO:00303342190.018
stem cell developmentGO:00488642190.017
response to extracellular stimulusGO:00099911270.017
inner ear receptor cell developmentGO:0060119390.017
locomotory behaviorGO:00076261950.017
positive regulation of purine nucleotide catabolic processGO:0033123880.017
sequestering of calcium ionGO:0051208180.017
defense response to virusGO:0051607680.017
protein modification by small protein conjugationGO:00324461870.017
response to dsrnaGO:0043331300.017
schwann cell differentiationGO:0014037260.017
cellular chemical homeostasisGO:00550822150.017
protein modification by small protein conjugation or removalGO:00706472070.017
ensheathment of neuronsGO:0007272760.017
camera type eye developmentGO:00430102660.017
negative regulation of phosphorus metabolic processGO:00105631840.017
establishment of rna localizationGO:0051236180.017
oxidation reduction processGO:00551143420.017
regulation of nucleoside metabolic processGO:00091181300.017
translationGO:0006412930.016
ion transmembrane transportGO:00342203610.016
positive regulation of apoptotic processGO:00430652170.016
positive regulation of nucleotide catabolic processGO:0030813880.016
regulation of cell cycle processGO:00105641600.016
glial cell differentiationGO:00100011310.016
inorganic ion transmembrane transportGO:00986602340.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
ossificationGO:00015032160.016
regulation of innate immune responseGO:0045088910.016
kidney developmentGO:00018222130.016
inner ear receptor cell differentiationGO:0060113610.016
digestive system developmentGO:00551232000.016
inorganic cation transmembrane transportGO:00986622070.016
rna localizationGO:0006403230.016
synapse organizationGO:00508081250.016
protein localization to membraneGO:00726571080.016
regulation of cell projection organizationGO:00313442060.016
spermatid developmentGO:00072861080.016
spermatid differentiationGO:00485151150.016
forebrain neuron differentiationGO:0021879520.016
negative regulation of protein phosphorylationGO:00019331260.016
regulation of nuclear divisionGO:0051783560.016
regulation of cellular component biogenesisGO:00440871810.016
regulation of response to biotic stimulusGO:0002831380.016
gtp metabolic processGO:00460391440.016
development of primary sexual characteristicsGO:00451371430.016
regulation of cell motilityGO:20001452360.015
positive regulation of gtp catabolic processGO:0033126850.015
regulation of myelinationGO:0031641200.015
negative regulation of molecular functionGO:00440922580.015
guanosine containing compound metabolic processGO:19010681440.015
metal ion homeostasisGO:00550651890.015
regulation of hormone levelsGO:00108172110.015
negative regulation of cellular component organizationGO:00511291940.015
sensory organ morphogenesisGO:00905962420.015
cell differentiation in spinal cordGO:0021515530.015
protein catabolic processGO:00301632210.015
glial cell developmentGO:0021782540.015
negative regulation of immune effector processGO:0002698550.015
viral processGO:0016032410.015
divalent inorganic cation transportGO:00725111780.015
regulation of cell adhesionGO:00301551540.015
positive regulation of cell deathGO:00109422240.015
viral genome replicationGO:0019079170.015
regulation of purine nucleotide metabolic processGO:19005421690.015
execution phase of apoptosisGO:0097194190.015
mitotic cell cycleGO:00002781950.015
interspecies interaction between organismsGO:0044419830.015
negative regulation of cytokine productionGO:0001818840.015
positive regulation of nervous system developmentGO:00519622210.015
negative regulation of phosphorylationGO:00423261660.015
negative regulation of phosphate metabolic processGO:00459361840.015
cellular response to organic cyclic compoundGO:0071407870.015
positive regulation of cellular catabolic processGO:00313311480.015
regulation of membrane potentialGO:00423911920.015
connective tissue developmentGO:00614481790.014
calcium ion homeostasisGO:00550741270.014
viral life cycleGO:0019058360.014
regulation of cell growthGO:0001558910.014
negative regulation of cell proliferationGO:00082852960.014
germ line stem cell divisionGO:004207820.014
extracellular matrix organizationGO:00301981470.014
response to nutrient levelsGO:00316671090.014
cation homeostasisGO:00550802120.014
pattern recognition receptor signaling pathwayGO:0002221470.014
b cell activationGO:00421131610.014
positive regulation of hydrolase activityGO:00513451480.014
response to insulinGO:00328681000.014
adult behaviorGO:00305341350.014
regulation of homeostatic processGO:00328441820.014
regulation of mapk cascadeGO:00434082480.014
leukocyte differentiationGO:00025213420.014
gliogenesisGO:00420631410.014
regulation of reactive oxygen species biosynthetic processGO:190342620.014
regulation of rig i signaling pathwayGO:003953520.014
multi multicellular organism processGO:00447061090.014
regulation of lymphocyte activationGO:00512492400.014
compound eye developmentGO:004874910.014
t cell activationGO:00421102890.014
extracellular structure organizationGO:00430621480.014
regulation of gliogenesisGO:0014013500.014
type i interferon productionGO:0032606290.014
symbiosis encompassing mutualism through parasitismGO:0044403830.013
regulation of kinase activityGO:00435492490.013
cell adhesionGO:00071553290.013
lung developmentGO:00303241640.013
negative regulation of organelle organizationGO:0010639900.013
schwann cell developmentGO:0014044220.013
organelle localizationGO:00516401790.013
cellular response to biotic stimulusGO:0071216920.013
synapse assemblyGO:0007416560.013
engulfment of apoptotic cellGO:004365230.013
regulation of protein kinase activityGO:00458592320.013
branching morphogenesis of an epithelial tubeGO:00487541590.013
negative regulation of protein modification processGO:00314001630.013
regulation of cell activationGO:00508652890.013
calcium ion transportGO:00068161590.013
organonitrogen compound biosynthetic processGO:19015661920.013
olfactory lobe developmentGO:0021988320.013
cellular metal ion homeostasisGO:00068751510.013
molting cycleGO:0042303900.013
regulation of protein processingGO:0070613960.013
columnar cuboidal epithelial cell developmentGO:0002066290.013
regulation of nucleotide metabolic processGO:00061401690.013
g protein coupled receptor signaling pathwayGO:00071862430.013
regulation of muscle tissue developmentGO:1901861970.013
response to organic cyclic compoundGO:00140701980.013
cell growthGO:00160491300.013
pallium developmentGO:00215431200.013
regulation of secretionGO:00510462740.013
negative regulation of cell cycleGO:00457861230.013
neural tube developmentGO:00219151600.013
mesenchyme developmentGO:00604851520.013
negative regulation of cellular protein metabolic processGO:00322692470.013
development of primary male sexual characteristicsGO:0046546880.013
appendage developmentGO:00487361660.013
urogenital system developmentGO:00016552610.013
synaptic transmissionGO:00072683290.013
glycoprotein metabolic processGO:00091001160.013
anatomical structure homeostasisGO:00602491450.013
negative regulation of protein metabolic processGO:00512482820.013
regulation of cellular component sizeGO:00325351210.013
appendage morphogenesisGO:00351071490.013
inflammatory responseGO:00069542440.012
sequestering of metal ionGO:0051238190.012
chromatin organizationGO:00063252060.012
muscle cell apoptotic processGO:0010657180.012
response to peptide hormoneGO:00434341270.012
respiratory tube developmentGO:00303231670.012
regulation of mitotic cell cycleGO:00073461260.012
limb developmentGO:00601731660.012
hair cycleGO:0042633900.012
establishment of protein localization to membraneGO:0090150540.012
spleen developmentGO:0048536390.012
response to growth factorGO:00708481980.012
positive regulation of gtpase activityGO:0043547850.012
single fertilizationGO:0007338820.012
endocytosisGO:00068971680.012
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.012
protein targetingGO:00066051430.012
lymphocyte proliferationGO:00466511640.012
regulation of mirna metabolic processGO:200062840.012
cardiac cell developmentGO:0055006410.012
cellular carbohydrate metabolic processGO:00442621190.012
gtp catabolic processGO:00061841430.012
sensory perceptionGO:00076002450.012
regulation of protein maturationGO:1903317960.012
outflow tract morphogenesisGO:0003151530.012
regulation of nucleotide catabolic processGO:00308111220.012
actin filament organizationGO:00070151130.012
cell substrate adhesionGO:00315891300.012
positive regulation of ras gtpase activityGO:0032320650.012
response to light stimulusGO:00094161350.012
regulation of establishment of protein localizationGO:00702011810.012
renal system developmentGO:00720012250.012
positive regulation of cell activationGO:00508671580.012
purine ribonucleoside monophosphate metabolic processGO:0009167800.012
neural precursor cell proliferationGO:00613511210.012
regulation of organ morphogenesisGO:20000271440.012
cellular ion homeostasisGO:00068731650.012
regulation of apoptotic signaling pathwayGO:20012331970.012
lymphocyte differentiationGO:00300982420.012
embryonic organ morphogenesisGO:00485622760.012
negative regulation of protein maturationGO:1903318790.012
divalent metal ion transportGO:00708381720.012
reactive oxygen species metabolic processGO:0072593840.012
anion transportGO:00068201770.012
single organism cell adhesionGO:00986021560.012
organic hydroxy compound metabolic processGO:19016152030.011
fertilizationGO:00095661270.011
regulation of vesicle mediated transportGO:00606271390.011
developmental growth involved in morphogenesisGO:00605601380.011
negative regulation of protein processingGO:0010955790.011
lipid localizationGO:00108761260.011
gonad developmentGO:00084061410.011
neuron deathGO:00709971540.011
regulation of protein catabolic processGO:00421761080.011
macromolecule glycosylationGO:0043413550.011
cellular lipid metabolic processGO:00442553230.011
negative regulation of mitotic cell cycleGO:0045930580.011
cellular response to dsrnaGO:0071359120.011
digestive tract morphogenesisGO:00485461470.011
myosin filament organizationGO:003103330.011
cellular amine metabolic processGO:0044106440.011
regulation of proteolysisGO:00301621640.011
carbohydrate homeostasisGO:00335001280.011
regulation of cell sizeGO:0008361720.011
cellular response to acid chemicalGO:0071229680.011
regulation of gtp catabolic processGO:00331241130.011
regulation of ossificationGO:00302781120.011
cellular ketone metabolic processGO:0042180840.011
regulation of t cell activationGO:00508631700.011
homeostasis of number of cellsGO:00488722100.011
negative regulation of schwann cell proliferationGO:001062610.011
positive regulation of growthGO:00459271040.011
spindle assemblyGO:0051225130.011
mitochondrion organizationGO:00070051340.011
regulation of transferase activityGO:00513382630.011
negative regulation of defense responseGO:0031348770.011
cellular response to insulin stimulusGO:0032869780.011
positive regulation of cell projection organizationGO:0031346950.011
cellular protein complex assemblyGO:00436231160.011
divalent inorganic cation homeostasisGO:00725071380.011
regulation of cell shapeGO:0008360390.011
regulation of chromosome organizationGO:0033044830.011
protein autophosphorylationGO:0046777610.011
oligodendrocyte differentiationGO:0048709530.011
limb morphogenesisGO:00351081490.011
reactive nitrogen species metabolic processGO:200105700.011
microtubule based transportGO:0010970500.011
glycoprotein biosynthetic processGO:0009101890.011
response to peptideGO:19016521360.011
endomembrane system organizationGO:00102561470.010
cardiocyte differentiationGO:0035051870.010
t cell differentiationGO:00302171740.010
nucleocytoplasmic transportGO:00069131390.010
chemotaxisGO:00069352470.010
cell matrix adhesionGO:0007160680.010
epithelial tube formationGO:00721751300.010
adult locomotory behaviorGO:0008344910.010
cytoskeleton dependent intracellular transportGO:0030705500.010
positive regulation of cell motilityGO:20001471160.010
regulation of protein localizationGO:00328802310.010
neuron apoptotic processGO:00514021420.010
lateral inhibitionGO:004633110.010
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018410.010
digestive tract developmentGO:00485651900.010
rhythmic processGO:00485111740.010
apoptotic dna fragmentationGO:000630970.010
positive regulation of neuron differentiationGO:00456661410.010
nucleoside monophosphate metabolic processGO:0009123850.010
cellular response to peptide hormone stimulusGO:0071375920.010
macromolecule methylationGO:00434141200.010
cell recognitionGO:0008037830.010
regulation of cytoskeleton organizationGO:00514931220.010
glucose homeostasisGO:00425931280.010
mrna catabolic processGO:0006402220.010
reactive oxygen species biosynthetic processGO:190340980.010

Drosha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.033
disease of cellular proliferationDOID:1456600.033
cancerDOID:16200.033
nervous system diseaseDOID:86300.032
disease of anatomical entityDOID:700.032
central nervous system diseaseDOID:33100.022
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012
neurodegenerative diseaseDOID:128900.011