IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Hsp90b1

heat shock protein 90, beta (Grp94), member 1

(Aliases: gp96,endoplasmin,Targ2,Tra-1,GRP94,Tra1,ERp99,TA-3)

Entrez: 22027
Ensembl: ENSMUSG00000020048
UniProtKB: P08113
UniProtKB: Q3UAD6

Process Predictions
Disease Predictions

Hsp90b1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
response to topologically incorrect protein	GO:0035966	25	0.999
endoplasmic reticulum unfolded protein response	GO:0030968	19	0.997
cellular response to topologically incorrect protein	GO:0035967	25	0.997
response to endoplasmic reticulum stress	GO:0034976	53	0.995
response to unfolded protein	GO:0006986	21	0.994
er nucleus signaling pathway	GO:0006984	27	0.987
protein transmembrane transport	GO:0071806	8	0.950
protein folding	GO:0006457	28	0.834
cellular response to interleukin 4	GO:0071353	21	0.786
positive regulation of extrinsic apoptotic signaling pathway	GO:2001238	34	0.731
protein refolding	GO:0042026	1	0.678
protein targeting to er	GO:0045047	2	0.673
cerebellar purkinje cell layer development	GO:0021680	26	0.651
establishment of protein localization to membrane	GO:0090150	54	0.647
protein targeting to membrane	GO:0006612	20	0.627
positive regulation of cell death	GO:0010942	224	0.470
protein localization to organelle	GO:0033365	185	0.415
cerebellum morphogenesis	GO:0021587	42	0.375
posttranslational protein targeting to membrane	GO:0006620	2	0.355
fertilization	GO:0009566	127	0.341
protein targeting	GO:0006605	143	0.327
intracellular protein transport	GO:0006886	204	0.322
er associated ubiquitin dependent protein catabolic process	GO:0030433	10	0.297	Human
positive regulation of programmed cell death	GO:0043068	218	0.294
cytoplasmic transport	GO:0016482	234	0.288
retina homeostasis	GO:0001895	23	0.256
transmembrane transport	GO:0055085	412	0.253
chaperone mediated protein folding	GO:0061077	10	0.234
positive regulation of protein modification by small protein conjugation or removal	GO:1903322	30	0.219
cotranslational protein targeting to membrane	GO:0006613	2	0.213
establishment of protein localization to organelle	GO:0072594	118	0.209
response to heat	GO:0009408	27	0.197
maintenance of protein localization in organelle	GO:0072595	2	0.191
regulation of macrophage activation	GO:0043030	17	0.181
regulation of protein kinase activity	GO:0045859	232	0.181
anatomical structure arrangement	GO:0048532	20	0.171
negative regulation of transforming growth factor beta receptor signaling pathway	GO:0030512	26	0.167
defecation	GO:0030421	1	0.163
cerebellum development	GO:0021549	77	0.161
srp dependent cotranslational protein targeting to membrane	GO:0006614	1	0.151
positive regulation of apoptotic process	GO:0043065	217	0.151
cellular response to nutrient levels	GO:0031669	64	0.150
extrinsic apoptotic signaling pathway	GO:0097191	126	0.150
cellular response to cytokine stimulus	GO:0071345	189	0.148
hindbrain morphogenesis	GO:0021575	46	0.145
response to antibiotic	GO:0046677	11	0.141
regulation of translation	GO:0006417	71	0.137
response to interleukin 4	GO:0070670	23	0.136
substantia nigra development	GO:0021762	2	0.134
genitalia morphogenesis	GO:0035112	11	0.129
lipid localization	GO:0010876	126	0.126	Worm
muscle cell differentiation	GO:0042692	261	0.125
cerebellar cortex development	GO:0021695	48	0.123
positive regulation of protein phosphorylation	GO:0001934	242	0.120
hindbrain development	GO:0030902	128	0.118
male sex differentiation	GO:0046661	109	0.116
positive regulation of transferase activity	GO:0051347	167	0.114
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.113
striated muscle myosin thick filament assembly	GO:0071688	1	0.113
positive regulation of phagocytosis	GO:0050766	26	0.099
glycoprotein biosynthetic process	GO:0009101	89	0.096
cellular response to toxic substance	GO:0097237	7	0.095
protein localization to membrane	GO:0072657	108	0.095
cell cell recognition	GO:0009988	44	0.094
clathrin mediated endocytosis	GO:0072583	7	0.094
er overload response	GO:0006983	6	0.094
pigmentation	GO:0043473	71	0.092
regulation of apoptotic signaling pathway	GO:2001233	197	0.091
positive regulation of protein kinase activity	GO:0045860	144	0.088
sperm egg recognition	GO:0035036	37	0.088
cellular response to growth factor stimulus	GO:0071363	197	0.088
regulation of systemic arterial blood pressure	GO:0003073	61	0.086
positive regulation of immune response to tumor cell	GO:0002839	6	0.086
posttranscriptional regulation of gene expression	GO:0010608	155	0.084
negative regulation of cellular response to growth factor stimulus	GO:0090288	46	0.084
cellular response to biotic stimulus	GO:0071216	92	0.083
neurological system process involved in regulation of systemic arterial blood pressure	GO:0001976	18	0.080
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.080	Human
peripheral nervous system axon regeneration	GO:0014012	2	0.079
positive regulation of macrophage activation	GO:0043032	10	0.078
organelle disassembly	GO:1903008	2	0.076
positive regulation of cell migration	GO:0030335	109	0.076
male anatomical structure morphogenesis	GO:0090598	4	0.075
response to yeast	GO:0001878	6	0.074
translation	GO:0006412	93	0.072
positive regulation of hydrolase activity	GO:0051345	148	0.071
ribonucleoprotein complex disassembly	GO:0032988	3	0.071
maintenance of location	GO:0051235	89	0.070	Worm
aromatic compound catabolic process	GO:0019439	286	0.070
protein catabolic process	GO:0030163	221	0.070	Human
positive regulation of kinase activity	GO:0033674	155	0.067
cellular response to extracellular stimulus	GO:0031668	81	0.065
body morphogenesis	GO:0010171	45	0.065
positive regulation of cardiac muscle contraction	GO:0060452	2	0.064
immunoglobulin production	GO:0002377	73	0.063
regulation of transferase activity	GO:0051338	263	0.063
regulation of kinase activity	GO:0043549	249	0.062
male genitalia morphogenesis	GO:0048808	4	0.062
somatic cell dna recombination	GO:0016444	51	0.061
positive regulation of t cell activation	GO:0050870	101	0.059
positive regulation of cell activation	GO:0050867	158	0.059
single fertilization	GO:0007338	82	0.058
apoptotic signaling pathway	GO:0097190	306	0.058
meiotic nuclear division	GO:0007126	115	0.058
4 hydroxyproline metabolic process	GO:0019471	5	0.057
toxin transport	GO:1901998	38	0.057
nuclear transport	GO:0051169	139	0.056
organelle localization	GO:0051640	179	0.056
protein ubiquitination	GO:0016567	171	0.056
lymphocyte activation involved in immune response	GO:0002285	93	0.056
circulatory system process	GO:0003013	197	0.054
response to extracellular stimulus	GO:0009991	127	0.053
cellular macromolecule catabolic process	GO:0044265	206	0.053	Human
protein modification by small protein conjugation or removal	GO:0070647	207	0.053
cytosolic calcium ion transport	GO:0060401	48	0.051
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	61	0.050
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.049
response to starvation	GO:0042594	65	0.048
regulation of ion transport	GO:0043269	215	0.048
cell recognition	GO:0008037	83	0.047
positive regulation of striated muscle contraction	GO:0045989	3	0.046
positive regulation of cell adhesion	GO:0045785	80	0.045
positive regulation of growth	GO:0045927	104	0.045
neural nucleus development	GO:0048857	22	0.045
multicellular organismal reproductive behavior	GO:0033057	23	0.045
regulation of cell motility	GO:2000145	236	0.044
metencephalon development	GO:0022037	89	0.043
spermatogenesis	GO:0007283	284	0.043
positive regulation of cell motility	GO:2000147	116	0.043
response to organic cyclic compound	GO:0014070	198	0.043	Human
positive regulation of protein modification process	GO:0031401	299	0.042
developmental pigmentation	GO:0048066	40	0.040
leukocyte activation involved in immune response	GO:0002366	126	0.040
protein localization to nucleus	GO:0034504	121	0.039
peptidyl proline hydroxylation to 4 hydroxy l proline	GO:0018401	2	0.039
cell activation involved in immune response	GO:0002263	126	0.039
mrna metabolic process	GO:0016071	84	0.039
protein import	GO:0017038	101	0.039
meiotic cell cycle	GO:0051321	122	0.038
cellular protein complex assembly	GO:0043623	116	0.038
regulation of cell migration	GO:0030334	219	0.038
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.038
cellular component assembly involved in morphogenesis	GO:0010927	139	0.038
cellular response to external stimulus	GO:0071496	88	0.038
regulation of protein ubiquitination	GO:0031396	52	0.037
male gamete generation	GO:0048232	285	0.036
multi multicellular organism process	GO:0044706	109	0.036
muscle tissue development	GO:0060537	308	0.036
lipid storage	GO:0019915	36	0.036	Worm
positive regulation of leukocyte mediated immunity	GO:0002705	70	0.036
regulation of calcium ion transport into cytosol	GO:0010522	31	0.036
negative regulation of molecular function	GO:0044092	258	0.035
establishment of protein localization to endoplasmic reticulum	GO:0072599	2	0.035
regulation of interferon gamma production	GO:0032649	57	0.035
rna splicing via transesterification reactions	GO:0000375	43	0.034
binding of sperm to zona pellucida	GO:0007339	34	0.034
midbrain development	GO:0030901	35	0.034
regulation of intracellular transport	GO:0032386	159	0.034
macromolecule catabolic process	GO:0009057	281	0.033	Human
anatomical structure homeostasis	GO:0060249	145	0.033
positive regulation of immune effector process	GO:0002699	107	0.033
response to nutrient levels	GO:0031667	109	0.033
myosin filament organization	GO:0031033	3	0.033
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.033
positive regulation of endocytosis	GO:0045807	42	0.032
membrane organization	GO:0061024	245	0.032
regulation of cell shape	GO:0008360	39	0.032
regulation of transposition	GO:0010528	2	0.032
response to growth factor	GO:0070848	198	0.032
regulation of organelle organization	GO:0033043	289	0.032
modification dependent protein catabolic process	GO:0019941	133	0.032	Human
regulation of cell projection organization	GO:0031344	206	0.032
cellular senescence	GO:0090398	11	0.031
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.031
calcium ion transport	GO:0006816	159	0.031
cellular response to glucose starvation	GO:0042149	5	0.031
production of molecular mediator of immune response	GO:0002440	103	0.030
negative regulation of cellular protein metabolic process	GO:0032269	247	0.030
regulation of metal ion transport	GO:0010959	106	0.030
somatic diversification of immunoglobulins involved in immune response	GO:0002208	36	0.030
positive regulation of cytokine production	GO:0001819	174	0.030
regulation of lymphocyte activation	GO:0051249	240	0.030
myeloid leukocyte activation	GO:0002274	83	0.030
protein modification by small protein conjugation	GO:0032446	187	0.030
regulation of cytokine production	GO:0001817	266	0.029
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.029
dna replication	GO:0006260	52	0.029
positive regulation of response to tumor cell	GO:0002836	6	0.029
regulation of response to biotic stimulus	GO:0002831	38	0.029
cytokine production	GO:0001816	319	0.029
protein targeting to mitochondrion	GO:0006626	6	0.029
maintenance of location in cell	GO:0051651	24	0.029
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.029
synaptic vesicle endocytosis	GO:0048488	19	0.028
eye pigmentation	GO:0048069	3	0.028
positive regulation of protein ubiquitination	GO:0031398	27	0.028
cellular response to starvation	GO:0009267	57	0.028
proteasomal protein catabolic process	GO:0010498	98	0.028	Human
regulation of lymphocyte mediated immunity	GO:0002706	84	0.027
positive regulation of dna replication	GO:0045740	9	0.027
divalent inorganic cation transport	GO:0072511	178	0.027
regulation of immune response to tumor cell	GO:0002837	6	0.027
mitochondrial transport	GO:0006839	36	0.027
negative regulation of transposition	GO:0010529	2	0.027
response to testosterone	GO:0033574	3	0.027
nucleoside triphosphate catabolic process	GO:0009143	205	0.027
response to transforming growth factor beta	GO:0071559	88	0.027
germ cell development	GO:0007281	185	0.027
regulation of hydrolase activity	GO:0051336	246	0.026	Human
regulation of endopeptidase activity	GO:0052548	89	0.026
interleukin 6 production	GO:0032635	58	0.026
intracellular steroid hormone receptor signaling pathway	GO:0030518	29	0.026
protein hydroxylation	GO:0018126	4	0.026
regulation of neuron differentiation	GO:0045664	281	0.026
cellular response to oxidative stress	GO:0034599	76	0.026
regulation of cellular response to stress	GO:0080135	159	0.026
regulation of tube size	GO:0035150	57	0.026
chemotaxis	GO:0006935	247	0.025
synaptic vesicle recycling	GO:0036465	19	0.025
protein n linked glycosylation via asparagine	GO:0018279	1	0.024
glycoprotein metabolic process	GO:0009100	116	0.024
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.024
regulation of cytoplasmic transport	GO:1903649	112	0.024
t cell activation	GO:0042110	289	0.024
ribonucleotide metabolic process	GO:0009259	291	0.024
leukocyte mediated immunity	GO:0002443	174	0.024
somatic diversification of immune receptors via germline recombination within a single locus	GO:0002562	51	0.024
ubiquitin dependent protein catabolic process	GO:0006511	129	0.024	Human
isotype switching	GO:0045190	36	0.023
positive regulation of cellular catabolic process	GO:0031331	148	0.023
actin cytoskeleton organization	GO:0030036	220	0.023	Human
skeletal myofibril assembly	GO:0014866	4	0.023
positive regulation of cell development	GO:0010720	237	0.023
protein export from nucleus	GO:0006611	20	0.023
response to temperature stimulus	GO:0009266	55	0.022
cellular calcium ion homeostasis	GO:0006874	119	0.022
action potential	GO:0001508	78	0.022
cytosolic calcium ion homeostasis	GO:0051480	70	0.022
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.022
response to estrogen	GO:0043627	24	0.022
establishment of protein localization to mitochondrion	GO:0072655	11	0.021
positive regulation of interferon alpha production	GO:0032727	4	0.021
regulation of membrane potential	GO:0042391	192	0.021
regulation of leukocyte mediated immunity	GO:0002703	104	0.021
regulation of calcium ion transport	GO:0051924	69	0.021
epithelial cell differentiation involved in salivary gland development	GO:0060690	2	0.020
immune effector process	GO:0002252	321	0.020
vesicle localization	GO:0051648	86	0.020
nitrogen compound transport	GO:0071705	271	0.020
epithelial cell development	GO:0002064	159	0.020
macromolecule glycosylation	GO:0043413	55	0.020
regulation of type i interferon production	GO:0032479	22	0.020
protein stabilization	GO:0050821	25	0.020
regulation of protein modification by small protein conjugation or removal	GO:1903320	57	0.020
protein import into nucleus	GO:0006606	95	0.020
somatic recombination of immunoglobulin genes involved in immune response	GO:0002204	36	0.019
urogenital system development	GO:0001655	261	0.019
b cell activation involved in immune response	GO:0002312	50	0.019
cell junction organization	GO:0034330	77	0.019
nucleocytoplasmic transport	GO:0006913	139	0.019
lymphocyte mediated immunity	GO:0002449	139	0.019
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	36	0.019
purine nucleoside metabolic process	GO:0042278	241	0.019
somatic diversification of immune receptors	GO:0002200	53	0.019
positive regulation of nuclease activity	GO:0032075	1	0.019
cytokine production involved in immune response	GO:0002367	34	0.019
positive regulation of dendritic cell chemotaxis	GO:2000510	1	0.019
spermatid differentiation	GO:0048515	115	0.019
developmental maturation	GO:0021700	193	0.019
carbohydrate metabolic process	GO:0005975	230	0.019
protein n linked glycosylation	GO:0006487	12	0.019
calcium ion transport into cytosol	GO:0060402	48	0.019
regeneration	GO:0031099	38	0.019
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.018
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.018
regulation of ion homeostasis	GO:2000021	64	0.018
positive regulation of adaptive immune response	GO:0002821	61	0.018
dna metabolic process	GO:0006259	303	0.018
protein localization to mitochondrion	GO:0070585	15	0.018
b cell activation	GO:0042113	161	0.018
striated muscle tissue development	GO:0014706	293	0.018
autophagy	GO:0006914	45	0.018
calcium ion homeostasis	GO:0055074	127	0.018
positive regulation of protein import into nucleus translocation	GO:0033160	1	0.018
wound healing	GO:0042060	157	0.018
regulation of homeostatic process	GO:0032844	182	0.018
cell growth	GO:0016049	130	0.018
extracellular matrix organization	GO:0030198	147	0.018
rna dependent dna replication	GO:0006278	3	0.018
maintenance of protein location in cell	GO:0032507	20	0.017
myosin filament assembly	GO:0031034	2	0.017
cardiocyte differentiation	GO:0035051	87	0.017
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.017
innate immune response	GO:0045087	157	0.017
carbohydrate derivative biosynthetic process	GO:1901137	183	0.017
regulation of t cell activation	GO:0050863	170	0.017
fat cell differentiation	GO:0045444	160	0.017
regulation of cell adhesion	GO:0030155	154	0.017
regulation of dna replication	GO:0006275	17	0.017
protein localization to plasma membrane	GO:0072659	57	0.017
lymphocyte proliferation	GO:0046651	164	0.016
carbohydrate homeostasis	GO:0033500	128	0.016
regulation of cysteine type endopeptidase activity	GO:2000116	65	0.016
multicellular organismal homeostasis	GO:0048871	164	0.016
cation homeostasis	GO:0055080	212	0.015
regulation of proteolysis	GO:0030162	164	0.015
cation transport	GO:0006812	399	0.015
cellular amino acid metabolic process	GO:0006520	103	0.015
cell chemotaxis	GO:0060326	81	0.015
response to steroid hormone	GO:0048545	56	0.015
interferon gamma production	GO:0032609	67	0.015
cellular chemical homeostasis	GO:0055082	215	0.015
macrophage activation	GO:0042116	27	0.015
positive regulation of cell substrate adhesion	GO:0010811	47	0.015
myd88 dependent toll like receptor signaling pathway	GO:0002755	7	0.015
placenta development	GO:0001890	140	0.015
reproductive behavior	GO:0019098	32	0.015
regulation of circadian sleep wake cycle sleep	GO:0045187	3	0.015
somatic diversification of immunoglobulins	GO:0016445	43	0.015
negative regulation of protein metabolic process	GO:0051248	282	0.015
interleukin 6 secretion	GO:0072604	3	0.015
multicellular organismal signaling	GO:0035637	91	0.015
single organism cell adhesion	GO:0098602	156	0.015
leukocyte proliferation	GO:0070661	172	0.015
regulation of cellular ketone metabolic process	GO:0010565	66	0.014
multicellular organism growth	GO:0035264	161	0.014
stress granule disassembly	GO:0035617	2	0.014
neuron migration	GO:0001764	122	0.014
sensory organ morphogenesis	GO:0090596	242	0.014
homeostasis of number of cells	GO:0048872	210	0.014
positive regulation of growth hormone secretion	GO:0060124	3	0.014
fatty acid metabolic process	GO:0006631	121	0.014
divalent metal ion transport	GO:0070838	172	0.014
spermatid development	GO:0007286	108	0.014
regulation of protein stability	GO:0031647	52	0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	62	0.014
cation transmembrane transport	GO:0098655	266	0.014
dna recombination	GO:0006310	92	0.014
regulation of cell cycle	GO:0051726	281	0.014
positive regulation of t cell mediated immunity	GO:0002711	24	0.014
establishment of synaptic vesicle localization	GO:0097480	57	0.014
zymogen activation	GO:0031638	41	0.013
synaptic transmission	GO:0007268	329	0.013
establishment of organelle localization	GO:0051656	122	0.013
nucleoside catabolic process	GO:0009164	206	0.013
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.013
regulation of circadian sleep wake cycle	GO:0042749	3	0.013
rna splicing	GO:0008380	54	0.013
transmission of nerve impulse	GO:0019226	76	0.013
ribose phosphate metabolic process	GO:0019693	291	0.013
insulin metabolic process	GO:1901142	3	0.013
amine metabolic process	GO:0009308	45	0.013
regulation of dendritic cell chemotaxis	GO:2000508	1	0.013
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.013
forebrain development	GO:0030900	302	0.013
kidney development	GO:0001822	213	0.013
positive regulation of lymphocyte mediated immunity	GO:0002708	62	0.013
compound eye development	GO:0048749	1	0.013
tissue homeostasis	GO:0001894	115	0.013
microtubule cytoskeleton organization	GO:0000226	157	0.012
response to inorganic substance	GO:0010035	96	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.012
establishment of vesicle localization	GO:0051650	81	0.012
leukocyte differentiation	GO:0002521	342	0.012
positive regulation of interferon gamma production	GO:0032729	39	0.012
plasma membrane organization	GO:0007009	90	0.012
regulation of cytoskeleton organization	GO:0051493	122	0.012
negative regulation of phosphorus metabolic process	GO:0010563	184	0.012
peptidyl proline hydroxylation	GO:0019511	3	0.012
response to lipopolysaccharide	GO:0032496	128	0.012
regulation of cell activation	GO:0050865	289	0.012
negative regulation of nervous system development	GO:0051961	156	0.012
cellular homeostasis	GO:0019725	240	0.012
molting cycle	GO:0042303	90	0.012
regulation of innate immune response	GO:0045088	91	0.012
regulation of cell substrate adhesion	GO:0010810	73	0.012
angiogenesis	GO:0001525	201	0.012
toll like receptor signaling pathway	GO:0002224	38	0.012
positive regulation of nervous system development	GO:0051962	221	0.012
glucose metabolic process	GO:0006006	92	0.012
leukocyte migration	GO:0050900	124	0.012
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.012
neuron apoptotic process	GO:0051402	142	0.012
regulation of multi organism process	GO:0043900	111	0.012
cellular response to lipopolysaccharide	GO:0071222	77	0.012
regulation of establishment of protein localization	GO:0070201	181	0.012
cellular ketone metabolic process	GO:0042180	84	0.011
negative regulation of cell development	GO:0010721	169	0.011
regulation of hormone levels	GO:0010817	211	0.011
glial cell differentiation	GO:0010001	131	0.011
genitalia development	GO:0048806	37	0.011
cellular lipid metabolic process	GO:0044255	323	0.011
cellular ion homeostasis	GO:0006873	165	0.011
protein maturation	GO:0051604	176	0.011
striated muscle cell development	GO:0055002	125	0.011
ribosomal subunit export from nucleus	GO:0000054	1	0.011
pore complex assembly	GO:0046931	3	0.011
cellular nitrogen compound catabolic process	GO:0044270	280	0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002822	87	0.011
peptide transport	GO:0015833	133	0.011
response to radiation	GO:0009314	165	0.011
reactive nitrogen species metabolic process	GO:2001057	0	0.011
regulation of protein serine threonine kinase activity	GO:0071900	157	0.011
pharynx development	GO:0060465	1	0.011
negative regulation of neuron projection regeneration	GO:0070571	3	0.011
divalent inorganic cation homeostasis	GO:0072507	138	0.011
lateral inhibition	GO:0046331	1	0.011
establishment of protein localization to plasma membrane	GO:0090002	34	0.011
oxidation reduction process	GO:0055114	342	0.011
vesicle uncoating	GO:0072319	4	0.011
inorganic ion transmembrane transport	GO:0098660	234	0.011
immunoglobulin mediated immune response	GO:0016064	69	0.011
locomotory behavior	GO:0007626	195	0.011
blood vessel morphogenesis	GO:0048514	285	0.011
regulation of endocytosis	GO:0030100	69	0.011
substrate adhesion dependent cell spreading	GO:0034446	30	0.011
regulation of cellular catabolic process	GO:0031329	242	0.011
cellular amine metabolic process	GO:0044106	44	0.010
oocyte construction	GO:0007308	2	0.010
detection of stimulus	GO:0051606	84	0.010
adaptive immune response	GO:0002250	155	0.010
multicellular organismal aging	GO:0010259	24	0.010
positive regulation of response to biotic stimulus	GO:0002833	15	0.010
regulation of vesicle mediated transport	GO:0060627	139	0.010
cell adhesion	GO:0007155	329	0.010
morphogenesis of embryonic epithelium	GO:0016331	159	0.010
purine nucleoside catabolic process	GO:0006152	205	0.010
neural tube development	GO:0021915	160	0.010
synaptic vesicle transport	GO:0048489	57	0.010
glucose homeostasis	GO:0042593	128	0.010
leukocyte chemotaxis	GO:0030595	69	0.010

Hsp90b1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.079
nervous system disease	DOID:863	0.079
central nervous system disease	DOID:331	0.050
paraplegia	DOID:607	0.039
hereditary spastic paraplegia	DOID:2476	0.039
sensory system disease	DOID:0050155	0.014
cancer	DOID:162	0.014
disease of cellular proliferation	DOID:14566	0.014
hematologic cancer	DOID:2531	0.013
organ system cancer	DOID:0050686	0.013
bone marrow cancer	DOID:4960	0.013
immune system cancer	DOID:0060083	0.013
bone disease	DOID:0080001	0.012
musculoskeletal system disease	DOID:17	0.012
bone development disease	DOID:0080006	0.012
connective tissue disease	DOID:65	0.012

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