IMP: Integrative Multi-species Prediction

Mus musculus

56 known processes

Hmgb3

high mobility group box 3

(Aliases: Hmg4,Hmg2a)

Ensembl: ENSMUSG00000015217
Entrez: 15354
UniProtKB: O54879
UniProtKB: Q544R9

Process Predictions
Disease Predictions

Hmgb3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
spermatogenesis	GO:0007283	284	0.222	Mouse
cellular response to dna damage stimulus	GO:0006974	207	0.192
negative regulation of cellular component organization	GO:0051129	194	0.150	Mouse
germ cell development	GO:0007281	185	0.145	Mouse
regulation of microtubule polymerization or depolymerization	GO:0031110	20	0.140
spermatid differentiation	GO:0048515	115	0.127	Mouse
male gamete generation	GO:0048232	285	0.126	Mouse
intracellular mrna localization	GO:0008298	4	0.120
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	1	0.118
dna metabolic process	GO:0006259	303	0.102
spermatid development	GO:0007286	108	0.091	Mouse
positive regulation of protein modification process	GO:0031401	299	0.091	Mouse
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.088
oxidation reduction process	GO:0055114	342	0.082	Mouse
mitotic cell cycle process	GO:1903047	159	0.082
mrna metabolic process	GO:0016071	84	0.079
regulation of organelle organization	GO:0033043	289	0.073
small gtpase mediated signal transduction	GO:0007264	97	0.073
regulation of cell cycle	GO:0051726	281	0.068
mitotic cell cycle	GO:0000278	195	0.065
nucleobase containing small molecule metabolic process	GO:0055086	352	0.063
dna repair	GO:0006281	107	0.062
regulation of cellular component biogenesis	GO:0044087	181	0.062
oocyte construction	GO:0007308	2	0.060
regulation of transferase activity	GO:0051338	263	0.058	Mouse
purine containing compound metabolic process	GO:0072521	311	0.056
microtubule cytoskeleton organization	GO:0000226	157	0.056
organelle fission	GO:0048285	170	0.055
organonitrogen compound biosynthetic process	GO:1901566	192	0.054
negative regulation of molecular function	GO:0044092	258	0.053
protein ubiquitination	GO:0016567	171	0.052
response to molecule of bacterial origin	GO:0002237	143	0.052
response to lipopolysaccharide	GO:0032496	128	0.050
epithelial tube morphogenesis	GO:0060562	303	0.048
negative regulation of protein metabolic process	GO:0051248	282	0.048
regulation of cell activation	GO:0050865	289	0.048
regulation of cellular amine metabolic process	GO:0033238	20	0.047
oocyte axis specification	GO:0007309	2	0.046
cellular ketone metabolic process	GO:0042180	84	0.045
amine metabolic process	GO:0009308	45	0.045
ras protein signal transduction	GO:0007265	77	0.045
chromatin organization	GO:0006325	206	0.043
glycosyl compound metabolic process	GO:1901657	246	0.043
cellular amino acid metabolic process	GO:0006520	103	0.043
nucleotide metabolic process	GO:0009117	332	0.043
cellular lipid metabolic process	GO:0044255	323	0.043
regionalization	GO:0003002	337	0.042
negative regulation of organelle organization	GO:0010639	90	0.042
meiosis i	GO:0007127	60	0.042
macromolecule catabolic process	GO:0009057	281	0.041	Mouse
adult behavior	GO:0030534	135	0.039
adult locomotory behavior	GO:0008344	91	0.039
chromatin modification	GO:0016568	187	0.039
nucleoside phosphate metabolic process	GO:0006753	338	0.039
developmental maturation	GO:0021700	193	0.038
microtubule polymerization or depolymerization	GO:0031109	26	0.038
regulation of mitotic cell cycle	GO:0007346	126	0.038
generation of precursor metabolites and energy	GO:0006091	103	0.038	Mouse
cytoplasmic transport	GO:0016482	234	0.037
posttranscriptional regulation of gene expression	GO:0010608	155	0.037
sensory perception	GO:0007600	245	0.037
oocyte anterior posterior axis specification	GO:0007314	2	0.037
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.037	Mouse
protein methylation	GO:0006479	81	0.037
purine ribonucleotide metabolic process	GO:0009150	290	0.037
pole plasm assembly	GO:0007315	2	0.037
regulation of glycogen catabolic process	GO:0005981	2	0.036	Mouse
regulation of cellular ketone metabolic process	GO:0010565	66	0.036
protein localization to organelle	GO:0033365	185	0.035
inflammatory response	GO:0006954	244	0.035
regulation of cytoskeleton organization	GO:0051493	122	0.035
wound healing	GO:0042060	157	0.035
negative regulation of cell activation	GO:0050866	111	0.034
negative regulation of microtubule polymerization or depolymerization	GO:0031111	15	0.034
peptidyl amino acid modification	GO:0018193	336	0.034
locomotory behavior	GO:0007626	195	0.034
cellular amine metabolic process	GO:0044106	44	0.034
purine nucleotide metabolic process	GO:0006163	302	0.034
histone modification	GO:0016570	159	0.033
leukocyte differentiation	GO:0002521	342	0.033
meiotic nuclear division	GO:0007126	115	0.033
carbohydrate derivative biosynthetic process	GO:1901137	183	0.033
nucleoside phosphate catabolic process	GO:1901292	222	0.032
axonogenesis	GO:0007409	274	0.032
microtubule based process	GO:0007017	236	0.032
homeostasis of number of cells	GO:0048872	210	0.032
regulation of apoptotic signaling pathway	GO:2001233	197	0.032	Mouse
establishment or maintenance of cell polarity	GO:0007163	86	0.032
response to organic cyclic compound	GO:0014070	198	0.031	Mouse
response to oxidative stress	GO:0006979	123	0.031
organic hydroxy compound metabolic process	GO:1901615	203	0.031
cell fate commitment	GO:0045165	210	0.031
purine ribonucleoside metabolic process	GO:0046128	241	0.031
nucleoside metabolic process	GO:0009116	246	0.030
mitotic nuclear division	GO:0007067	48	0.030
mitochondrion organization	GO:0007005	134	0.030
ribose phosphate metabolic process	GO:0019693	291	0.029
skin development	GO:0043588	220	0.029
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.029
regulation of cellular response to stress	GO:0080135	159	0.029
cellular nitrogen compound catabolic process	GO:0044270	280	0.029
development of primary sexual characteristics	GO:0045137	143	0.029	Mouse
negative regulation of phosphate metabolic process	GO:0045936	184	0.028
carbohydrate metabolic process	GO:0005975	230	0.028	Mouse
cellular response to lipid	GO:0071396	145	0.028
nuclear division	GO:0000280	158	0.028
wnt signaling pathway	GO:0016055	188	0.028
ribonucleotide metabolic process	GO:0009259	291	0.028
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.028
positive regulation of nervous system development	GO:0051962	221	0.027
negative regulation of cytoskeleton organization	GO:0051494	36	0.027
methylation	GO:0032259	134	0.027
positive regulation of cellular amine metabolic process	GO:0033240	5	0.027
meiotic cell cycle process	GO:1903046	77	0.026
regulation of cellular amino acid metabolic process	GO:0006521	5	0.026
nitrogen compound transport	GO:0071705	271	0.026
positive regulation of protein phosphorylation	GO:0001934	242	0.026	Mouse
negative regulation of cell cycle	GO:0045786	123	0.026
regulation of protein kinase activity	GO:0045859	232	0.026	Mouse
positive regulation of organelle organization	GO:0010638	128	0.026
intrinsic apoptotic signaling pathway	GO:0097193	132	0.026
apoptotic signaling pathway	GO:0097190	306	0.026	Mouse
aromatic compound catabolic process	GO:0019439	286	0.025
small molecule biosynthetic process	GO:0044283	132	0.025
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.025	Mouse
digestive tract morphogenesis	GO:0048546	147	0.025
synaptic transmission	GO:0007268	329	0.025
negative regulation of phagocytosis	GO:0050765	4	0.025	Mouse
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.025
positive regulation of protein kinase activity	GO:0045860	144	0.024	Mouse
histone methylation	GO:0016571	71	0.024
double strand break repair	GO:0006302	48	0.024
heterocycle catabolic process	GO:0046700	280	0.024
regulation of protein localization	GO:0032880	231	0.024
negative regulation of cellular protein metabolic process	GO:0032269	247	0.024
mitotic cytokinesis	GO:0000281	4	0.024
digestive tract development	GO:0048565	190	0.023
3 utr mediated mrna stabilization	GO:0070935	2	0.023
chromosome segregation	GO:0007059	48	0.023
negative regulation of phosphorylation	GO:0042326	166	0.023
meiotic cell cycle	GO:0051321	122	0.023
purine nucleoside metabolic process	GO:0042278	241	0.023
regulation of mapk cascade	GO:0043408	248	0.022
positive regulation of transferase activity	GO:0051347	167	0.022	Mouse
cofactor metabolic process	GO:0051186	80	0.022
epithelial tube formation	GO:0072175	130	0.022
dna recombination	GO:0006310	92	0.022
regulation of protein serine threonine kinase activity	GO:0071900	157	0.022
lipid biosynthetic process	GO:0008610	179	0.022
organic cyclic compound catabolic process	GO:1901361	295	0.022
regulation of response to wounding	GO:1903034	189	0.022
translation	GO:0006412	93	0.022
compound eye development	GO:0048749	1	0.022
positive regulation of cellular catabolic process	GO:0031331	148	0.022	Mouse
tube formation	GO:0035148	140	0.022
mapk cascade	GO:0000165	281	0.021
cellular protein complex assembly	GO:0043623	116	0.021
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	45	0.021	Mouse
base excision repair	GO:0006284	9	0.021
stem cell differentiation	GO:0048863	268	0.021
transmembrane transport	GO:0055085	412	0.021
regulation of response to dna damage stimulus	GO:2001020	34	0.021
cell growth	GO:0016049	130	0.021
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.021
nucleoside phosphate biosynthetic process	GO:1901293	79	0.021
cellular homeostasis	GO:0019725	240	0.021
digestive system development	GO:0055123	200	0.021
negative regulation of phosphorus metabolic process	GO:0010563	184	0.021
purine nucleotide catabolic process	GO:0006195	211	0.020
placenta development	GO:0001890	140	0.020
cell maturation	GO:0048469	127	0.020
covalent chromatin modification	GO:0016569	163	0.020
regulation of lymphocyte activation	GO:0051249	240	0.020
synapse organization	GO:0050808	125	0.020
ossification	GO:0001503	216	0.020
positive regulation of cell development	GO:0010720	237	0.020
regulation of binding	GO:0051098	111	0.019	Mouse
innate immune response	GO:0045087	157	0.019
regulation of translation	GO:0006417	71	0.019
negative regulation of protein modification process	GO:0031400	163	0.019
gonad development	GO:0008406	141	0.019	Mouse
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.019
neural tube formation	GO:0001841	108	0.019
organonitrogen compound catabolic process	GO:1901565	264	0.019
negative regulation of leukocyte differentiation	GO:1902106	51	0.019
rna interference	GO:0016246	2	0.019
regulation of vesicle mediated transport	GO:0060627	139	0.019	Mouse
positive regulation of kinase activity	GO:0033674	155	0.018	Mouse
cell adhesion	GO:0007155	329	0.018
response to light stimulus	GO:0009416	135	0.018
regulation of lymphocyte differentiation	GO:0045619	107	0.018
mrna processing	GO:0006397	63	0.018
endocytosis	GO:0006897	168	0.018	Mouse
apoptotic mitochondrial changes	GO:0008637	48	0.018
intracellular protein transport	GO:0006886	204	0.018
cellular protein complex disassembly	GO:0043624	36	0.018
development of primary male sexual characteristics	GO:0046546	88	0.018	Mouse
morphogenesis of embryonic epithelium	GO:0016331	159	0.018
regulation of mrna stability	GO:0043488	23	0.018
synapsis	GO:0007129	34	0.018
ion transmembrane transport	GO:0034220	361	0.018
organophosphate catabolic process	GO:0046434	232	0.018
organophosphate biosynthetic process	GO:0090407	122	0.018
regulation of microtubule based process	GO:0032886	52	0.018
protein alkylation	GO:0008213	81	0.017
cell type specific apoptotic process	GO:0097285	268	0.017
response to organonitrogen compound	GO:0010243	246	0.017
cellular response to oxidative stress	GO:0034599	76	0.017
i kappab kinase nf kappab signaling	GO:0007249	85	0.017
oocyte differentiation	GO:0009994	35	0.017
negative regulation of cellular amine metabolic process	GO:0033239	1	0.017
cation transport	GO:0006812	399	0.017
organelle localization	GO:0051640	179	0.017
response to extracellular stimulus	GO:0009991	127	0.017
asymmetric stem cell division	GO:0098722	3	0.017
developmental growth involved in morphogenesis	GO:0060560	138	0.017
nucleoside triphosphate metabolic process	GO:0009141	230	0.017
gland development	GO:0048732	330	0.017
male meiosis	GO:0007140	37	0.017
neural tube development	GO:0021915	160	0.017
immune effector process	GO:0002252	321	0.017
ribonucleoside metabolic process	GO:0009119	245	0.017
coenzyme biosynthetic process	GO:0009108	23	0.017
negative regulation of cell proliferation	GO:0008285	296	0.017
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.017
purine nucleoside catabolic process	GO:0006152	205	0.016
cation transmembrane transport	GO:0098655	266	0.016
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.016
protein depolymerization	GO:0051261	34	0.016
nucleotide catabolic process	GO:0009166	217	0.016
oogenesis	GO:0048477	56	0.016
response to steroid hormone	GO:0048545	56	0.016	Mouse
oocyte development	GO:0048599	33	0.016
segmentation	GO:0035282	93	0.016
purine containing compound catabolic process	GO:0072523	213	0.016
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.016
chemotaxis	GO:0006935	247	0.016
negative regulation of b cell differentiation	GO:0045578	4	0.016
positive regulation of growth	GO:0045927	104	0.016
t cell activation	GO:0042110	289	0.016
protein modification by small protein conjugation or removal	GO:0070647	207	0.015
nucleoside monophosphate metabolic process	GO:0009123	85	0.015
purine ribonucleoside monophosphate metabolic process	GO:0009167	80	0.015
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.015
blood vessel morphogenesis	GO:0048514	285	0.015
regulation of ras protein signal transduction	GO:0046578	114	0.015
membrane organization	GO:0061024	245	0.015
regulation of establishment of protein localization	GO:0070201	181	0.015
negative regulation of mitotic cell cycle	GO:0045930	58	0.015
myeloid cell differentiation	GO:0030099	233	0.015
regulation of chromosome organization	GO:0033044	83	0.015
b cell activation	GO:0042113	161	0.015
respiratory system development	GO:0060541	190	0.015	Mouse
cofactor biosynthetic process	GO:0051188	41	0.015
mitotic g1 dna damage checkpoint	GO:0031571	4	0.015
positive regulation of neuron differentiation	GO:0045666	141	0.015
multi multicellular organism process	GO:0044706	109	0.015
organelle assembly	GO:0070925	177	0.015
regulation of secretion by cell	GO:1903530	249	0.015
monocarboxylic acid metabolic process	GO:0032787	191	0.015
regulation of dna damage checkpoint	GO:2000001	3	0.015
anatomical structure homeostasis	GO:0060249	145	0.015
leukocyte proliferation	GO:0070661	172	0.014
positive regulation of apoptotic process	GO:0043065	217	0.014
carbohydrate derivative catabolic process	GO:1901136	231	0.014
protein polymerization	GO:0051258	57	0.014
macromolecule methylation	GO:0043414	120	0.014
regulation of rna stability	GO:0043487	26	0.014
regulation of intrinsic apoptotic signaling pathway	GO:2001242	61	0.014
protein catabolic process	GO:0030163	221	0.014
nuclear import	GO:0051170	95	0.014
regulation of secretion	GO:0051046	274	0.014
protein maturation	GO:0051604	176	0.014
cellular macromolecule catabolic process	GO:0044265	206	0.014
protein processing	GO:0016485	163	0.014
female gamete generation	GO:0007292	74	0.014
epidermis development	GO:0008544	187	0.014
cellular protein catabolic process	GO:0044257	155	0.014
rho protein signal transduction	GO:0007266	32	0.014
regulation of defense response	GO:0031347	233	0.014
cytokine production	GO:0001816	319	0.014
regulation of cell cycle process	GO:0010564	160	0.014
male anatomical structure morphogenesis	GO:0090598	4	0.014
protein targeting	GO:0006605	143	0.014
response to inorganic substance	GO:0010035	96	0.014
determination of left right symmetry	GO:0007368	80	0.014
g1 s transition of mitotic cell cycle	GO:0000082	57	0.014
response to radiation	GO:0009314	165	0.014
regulation of proteolysis	GO:0030162	164	0.014
cellular chemical homeostasis	GO:0055082	215	0.014
regulation of phosphatidylcholine biosynthetic process	GO:2001245	2	0.014
sensory perception of mechanical stimulus	GO:0050954	107	0.014
regulation of mrna metabolic process	GO:1903311	43	0.014
epithelial cell proliferation	GO:0050673	174	0.014
regulation of hydrolase activity	GO:0051336	246	0.014
response to iron ion	GO:0010039	4	0.014
ribonucleotide catabolic process	GO:0009261	208	0.014
inorganic ion transmembrane transport	GO:0098660	234	0.013
muscle cell differentiation	GO:0042692	261	0.013
regulation of mrna processing	GO:0050684	41	0.013
negative regulation of microtubule polymerization	GO:0031115	2	0.013
canonical wnt signaling pathway	GO:0060070	130	0.013
regulation of epithelial cell proliferation	GO:0050678	141	0.013
regulation of b cell activation	GO:0050864	81	0.013
gene silencing by rna	GO:0031047	19	0.013
regulation of inflammatory response	GO:0050727	147	0.013
response to nutrient levels	GO:0031667	109	0.013
ear development	GO:0043583	200	0.013
cellular response to acid chemical	GO:0071229	68	0.013
nucleoside triphosphate catabolic process	GO:0009143	205	0.013
cellular carbohydrate metabolic process	GO:0044262	119	0.013	Mouse
dna conformation change	GO:0071103	37	0.013
lateral inhibition	GO:0046331	1	0.013
regulation of multi organism process	GO:0043900	111	0.013
dendrite development	GO:0016358	115	0.013
hexose metabolic process	GO:0019318	98	0.013	Mouse
male sex differentiation	GO:0046661	109	0.013	Mouse
positive regulation of intracellular transport	GO:0032388	70	0.013
ribonucleoside catabolic process	GO:0042454	206	0.013
regulation of g1 s transition of mitotic cell cycle	GO:2000045	35	0.013
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.013
regulation of nucleotide metabolic process	GO:0006140	169	0.013
regulation of kinase activity	GO:0043549	249	0.013	Mouse
regulation of intracellular protein transport	GO:0033157	82	0.013
engulfment of apoptotic cell	GO:0043652	3	0.013
stem cell development	GO:0048864	219	0.013
morphogenesis of a branching epithelium	GO:0061138	193	0.013
lung development	GO:0030324	164	0.013	Mouse
nucleoside catabolic process	GO:0009164	206	0.013
microtubule based movement	GO:0007018	84	0.013
establishment of protein localization to organelle	GO:0072594	118	0.012
regulation of purine nucleotide metabolic process	GO:1900542	169	0.012
glucan catabolic process	GO:0009251	5	0.012	Mouse
skeletal system development	GO:0001501	356	0.012
negative regulation of intracellular signal transduction	GO:1902532	167	0.012
angiogenesis	GO:0001525	201	0.012
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.012
amp metabolic process	GO:0046033	4	0.012
negative regulation of immune system process	GO:0002683	209	0.012
synapse assembly	GO:0007416	56	0.012
transmission of nerve impulse	GO:0019226	76	0.012
action potential	GO:0001508	78	0.012
regulation of leukocyte differentiation	GO:1902105	159	0.012
g protein coupled receptor signaling pathway	GO:0007186	243	0.012
developmental cell growth	GO:0048588	84	0.012
regulation of hormone levels	GO:0010817	211	0.012
regulation of ion transmembrane transport	GO:0034765	119	0.012
protein localization to nucleus	GO:0034504	121	0.012
nucleotide biosynthetic process	GO:0009165	78	0.012
glucose metabolic process	GO:0006006	92	0.012	Mouse
regulation of cell growth	GO:0001558	91	0.012
purine ribonucleotide catabolic process	GO:0009154	208	0.012
lymphocyte proliferation	GO:0046651	164	0.012
t cell proliferation	GO:0042098	120	0.012
positive regulation of mapk cascade	GO:0043410	170	0.012
sensory perception of sound	GO:0007605	97	0.012
cell junction organization	GO:0034330	77	0.012
establishment of organelle localization	GO:0051656	122	0.012
regulation of chromatin modification	GO:1903308	57	0.011
regulation of neuron differentiation	GO:0045664	281	0.011
regulation of lipid metabolic process	GO:0019216	118	0.011
negative regulation of protein phosphorylation	GO:0001933	126	0.011
cellular polysaccharide catabolic process	GO:0044247	5	0.011	Mouse
positive regulation of cell cycle	GO:0045787	92	0.011
rhythmic process	GO:0048511	174	0.011
negative regulation of b cell activation	GO:0050869	27	0.011
regulation of t cell activation	GO:0050863	170	0.011
regulation of peptidase activity	GO:0052547	96	0.011
cellular response to growth factor stimulus	GO:0071363	197	0.011
heart contraction	GO:0060047	93	0.011
multicellular organismal homeostasis	GO:0048871	164	0.011
glycosyl compound catabolic process	GO:1901658	206	0.011
protein modification by small protein conjugation	GO:0032446	187	0.011
rna localization	GO:0006403	23	0.011
positive regulation of mrna metabolic process	GO:1903313	17	0.011
regulation of nucleotide catabolic process	GO:0030811	122	0.011
regulation of myeloid cell differentiation	GO:0045637	96	0.011
regulation of intracellular transport	GO:0032386	159	0.011
dna integrity checkpoint	GO:0031570	28	0.011
response to acid chemical	GO:0001101	111	0.011
extrinsic apoptotic signaling pathway	GO:0097191	126	0.011	Mouse
rna processing	GO:0006396	105	0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.011
extracellular structure organization	GO:0043062	148	0.011
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.011
neuron death	GO:0070997	154	0.011
regulation of cell cycle phase transition	GO:1901987	77	0.011
regulation of carbohydrate metabolic process	GO:0006109	75	0.011	Mouse
regulation of endocytosis	GO:0030100	69	0.011	Mouse
cell junction assembly	GO:0034329	52	0.011
cell division	GO:0051301	120	0.011
cellular response to molecule of bacterial origin	GO:0071219	83	0.011
response to growth factor	GO:0070848	198	0.011
regulation of body fluid levels	GO:0050878	162	0.010
ribonucleotide biosynthetic process	GO:0009260	59	0.010
cellular response to organonitrogen compound	GO:0071417	145	0.010
mitotic chromosome condensation	GO:0007076	1	0.010
pharynx development	GO:0060465	1	0.010
dna packaging	GO:0006323	30	0.010
dephosphorylation	GO:0016311	129	0.010
negative regulation of translation	GO:0017148	22	0.010
sulfur compound metabolic process	GO:0006790	100	0.010
monosaccharide metabolic process	GO:0005996	106	0.010	Mouse
carboxylic acid biosynthetic process	GO:0046394	86	0.010
myeloid cell homeostasis	GO:0002262	114	0.010
telencephalon development	GO:0021537	186	0.010
circulatory system process	GO:0003013	197	0.010
mesenchymal cell differentiation	GO:0048762	107	0.010
regulation of protein modification by small protein conjugation or removal	GO:1903320	57	0.010
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.010
regulation of membrane potential	GO:0042391	192	0.010
divalent metal ion transport	GO:0070838	172	0.010
respiratory tube development	GO:0030323	167	0.010	Mouse
protein import into nucleus	GO:0006606	95	0.010
ribose phosphate biosynthetic process	GO:0046390	59	0.010
posttranscriptional gene silencing by rna	GO:0035194	10	0.010
nucleocytoplasmic transport	GO:0006913	139	0.010
negative regulation of transferase activity	GO:0051348	85	0.010

Hmgb3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.036
central nervous system disease	DOID:331	0.036
nervous system disease	DOID:863	0.036
neurodegenerative disease	DOID:1289	0.015
musculoskeletal system disease	DOID:17	0.013
motor neuron disease	DOID:231	0.011
amyotrophic lateral sclerosis	DOID:332	0.011

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