Mus musculus

70 known processes

Atxn2

ataxin 2

(Aliases: ATX2,9630045M23Rik,Sca2,AW544490)

Atxn2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayGO:190103060.384
positive regulation of mitochondrion organizationGO:0010822170.250
spermatogenesisGO:00072832840.174
dna metabolic processGO:00062593030.173
carbohydrate derivative catabolic processGO:19011362310.167
ribonucleotide metabolic processGO:00092592910.157
glycosyl compound catabolic processGO:19016582060.134
positive regulation of necrotic cell deathGO:001094010.125
positive regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902110110.122
covalent chromatin modificationGO:00165691630.121
ribonucleoside triphosphate metabolic processGO:00091992200.116
male gamete generationGO:00482322850.113
cellular nitrogen compound catabolic processGO:00442702800.113
regulation of organelle organizationGO:00330432890.106
Fly
purine ribonucleoside metabolic processGO:00461282410.105
apoptotic mitochondrial changesGO:0008637480.105
heterocycle catabolic processGO:00467002800.102
protein modification by small protein conjugation or removalGO:00706472070.101
nucleoside triphosphate catabolic processGO:00091432050.101
protein localization to organelleGO:00333651850.100
regulation of protein localizationGO:00328802310.098
small gtpase mediated signal transductionGO:0007264970.096
organic cyclic compound catabolic processGO:19013612950.093
clathrin mediated endocytosisGO:007258370.092
ras protein signal transductionGO:0007265770.090
nucleoside phosphate catabolic processGO:19012922220.090
regulation of mapk cascadeGO:00434082480.088
positive regulation of cellular catabolic processGO:00313311480.088
nucleoside triphosphate metabolic processGO:00091412300.086
purine containing compound catabolic processGO:00725232130.086
organophosphate catabolic processGO:00464342320.084
mitochondrial outer membrane permeabilization involved in programmed cell deathGO:1902686110.084
regulation of cell cycleGO:00517262810.083
histone lysine methylationGO:0034968500.081
purine ribonucleoside triphosphate metabolic processGO:00092052200.079
regulation of apoptotic signaling pathwayGO:20012331970.077
nucleoside metabolic processGO:00091162460.073
posttranscriptional regulation of gene expressionGO:00106081550.072
Fly
protein modification by small protein conjugationGO:00324461870.071
phosphatidic acid biosynthetic processGO:000665420.070
purine nucleoside metabolic processGO:00422782410.068
gtp metabolic processGO:00460391440.068
regulation of cellular catabolic processGO:00313292420.067
purine nucleotide metabolic processGO:00061633020.066
regulation of mitochondrial membrane permeabilityGO:0046902170.066
purine ribonucleotide catabolic processGO:00091542080.065
organophosphate biosynthetic processGO:00904071220.063
purine nucleoside triphosphate metabolic processGO:00091442260.062
regulation of establishment of protein localizationGO:00702011810.062
chromatin organizationGO:00063252060.060
ribonucleoside triphosphate catabolic processGO:00092031990.060
positive regulation of organelle organizationGO:00106381280.057
membrane tubulationGO:009732040.057
protein ubiquitinationGO:00165671710.057
nucleotide catabolic processGO:00091662170.056
ribonucleoside catabolic processGO:00424542060.056
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayGO:190074030.055
ribose phosphate metabolic processGO:00196932910.055
histone modificationGO:00165701590.055
macromolecule catabolic processGO:00090572810.054
lipid biosynthetic processGO:00086101790.052
establishment of mitochondrion localizationGO:005165440.052
negative regulation of cellular protein metabolic processGO:00322692470.051
nucleoside phosphate metabolic processGO:00067533380.050
purine nucleotide catabolic processGO:00061952110.050
endocytosisGO:00068971680.049
Fly
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108140.048
regulation of cellular response to stressGO:00801351590.048
purine containing compound metabolic processGO:00725213110.048
mitochondrion organizationGO:00070051340.048
spermatid differentiationGO:00485151150.048
purine ribonucleoside catabolic processGO:00461302050.048
mitochondrial membrane organizationGO:0007006260.046
glycerolipid metabolic processGO:00464861220.046
purine ribonucleoside triphosphate catabolic processGO:00092071990.046
purine ribonucleotide metabolic processGO:00091502900.046
mitochondrial outer membrane permeabilizationGO:0097345100.044
aromatic compound catabolic processGO:00194392860.044
guanosine containing compound catabolic processGO:19010691440.044
cellular lipid metabolic processGO:00442553230.044
ribonucleotide catabolic processGO:00092612080.044
ribonucleoside metabolic processGO:00091192450.043
glycosyl compound metabolic processGO:19016572460.043
regulation of nucleotide catabolic processGO:00308111220.042
compound eye developmentGO:004874910.042
Fly
apoptotic signaling pathwayGO:00971903060.042
nucleoside catabolic processGO:00091642060.040
protein localization to membraneGO:00726571080.039
organonitrogen compound catabolic processGO:19015652640.038
phosphatidic acid metabolic processGO:004647320.038
cellular macromolecule catabolic processGO:00442652060.038
organelle fissionGO:00482851700.037
rab protein signal transductionGO:003248210.036
regulation of synaptic growth at neuromuscular junctionGO:000858240.035
histone methylationGO:0016571710.035
protein insertion into mitochondrial membraneGO:005120440.035
negative regulation of synapse assemblyGO:005196430.034
cellular response to dna damage stimulusGO:00069742070.034
mapk cascadeGO:00001652810.034
regulation of gtp catabolic processGO:00331241130.033
microtubule based processGO:00070172360.033
purine nucleoside triphosphate catabolic processGO:00091462030.033
negative regulation of phosphorus metabolic processGO:00105631840.033
regulation of membrane permeabilityGO:0090559180.033
cytoplasmic transportGO:00164822340.033
purine nucleoside catabolic processGO:00061522050.032
negative regulation of mesenchymal cell proliferation involved in lung developmentGO:200079120.032
mitotic cytokinesisGO:000028140.032
regulation of intracellular transportGO:00323861590.032
meiosis iGO:0007127600.031
establishment of protein localization to organelleGO:00725941180.031
amine metabolic processGO:0009308450.031
methylationGO:00322591340.031
cellular amino acid metabolic processGO:00065201030.031
nucleobase containing small molecule metabolic processGO:00550863520.031
intracellular mrna localizationGO:000829840.031
cellular ketone metabolic processGO:0042180840.031
regulation of cell motilityGO:20001452360.031
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.031
receptor mediated endocytosisGO:0006898510.030
protein methylationGO:0006479810.030
guanosine containing compound metabolic processGO:19010681440.030
positive regulation of dna templated transcription elongationGO:003278620.030
regulation of hydrolase activityGO:00513362460.030
negative regulation of protein metabolic processGO:00512482820.029
positive regulation of mapk cascadeGO:00434101700.029
olfactory learningGO:000835520.029
Fly
establishment of protein localization to membraneGO:0090150540.029
endomembrane system organizationGO:00102561470.029
wnt signaling pathwayGO:00160551880.029
positive regulation of gtp catabolic processGO:0033126850.028
myelinationGO:0042552740.028
regulation of ras protein signal transductionGO:00465781140.028
synaptic transmissionGO:00072683290.028
Fly
regulation of purine nucleotide catabolic processGO:00331211220.027
negative regulation of intracellular signal transductionGO:19025321670.027
positive regulation of hydrolase activityGO:00513451480.027
macromolecule methylationGO:00434141200.027
regulation of nucleoside metabolic processGO:00091181300.027
nucleotide metabolic processGO:00091173320.027
regulation of vesicle mediated transportGO:00606271390.027
regulation of wnt signaling pathwayGO:00301111230.027
regulation of endocytosisGO:0030100690.027
i kappab kinase nf kappab signalingGO:0007249850.027
glycerolipid biosynthetic processGO:0045017500.027
macromolecule deacylationGO:0098732370.027
positive regulation of apoptotic signaling pathwayGO:2001235950.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
dna alkylationGO:0006305430.026
protein catabolic processGO:00301632210.026
regulation of purine nucleotide metabolic processGO:19005421690.025
microtubule based movementGO:0007018840.025
plasma membrane organizationGO:0007009900.025
gtp catabolic processGO:00061841430.025
rhythmic processGO:00485111740.025
Fly
purine nucleoside monophosphate metabolic processGO:0009126810.025
regionalizationGO:00030023370.025
positive regulation of nucleoside metabolic processGO:0045979910.025
organelle localizationGO:00516401790.025
membrane organizationGO:00610242450.024
positive regulation of ras gtpase activityGO:0032320650.024
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.024
glycerophospholipid metabolic processGO:0006650710.024
extracellular structure organizationGO:00430621480.024
dna methylationGO:0006306430.024
maternal determination of anterior posterior axis embryoGO:000835820.024
positive regulation of nervous system developmentGO:00519622210.024
nucleocytoplasmic transportGO:00069131390.024
chromosome segregationGO:0007059480.024
purine ribonucleoside monophosphate metabolic processGO:0009167800.024
negative regulation of phosphate metabolic processGO:00459361840.024
phospholipid biosynthetic processGO:0008654360.024
regulation of kinase activityGO:00435492490.023
skeletal system developmentGO:00015013560.023
positive regulation of cellular amine metabolic processGO:003324050.023
phospholipid metabolic processGO:0006644870.023
regulation of nucleotide metabolic processGO:00061401690.023
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayGO:190102870.023
cell divisionGO:00513011200.022
positive regulation of mitochondrial membrane permeabilityGO:0035794120.022
fertilizationGO:00095661270.022
male meiosis iGO:0007141160.022
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.022
regulation of cellular amino acid metabolic processGO:000652150.022
intracellular protein transportGO:00068862040.022
cellular amine metabolic processGO:0044106440.021
golgi to endosome transportGO:000689530.021
lateral inhibitionGO:004633110.021
pole plasm assemblyGO:000731520.021
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.021
regulation of protein catabolic processGO:00421761080.021
forebrain developmentGO:00309003020.021
positive regulation of programmed cell deathGO:00430682180.020
nuclear divisionGO:00002801580.020
cytoskeleton dependent intracellular transportGO:0030705500.020
regulation of protein complex assemblyGO:0043254830.020
Fly
meiotic nuclear divisionGO:00071261150.020
chromatin modificationGO:00165681870.020
neuron neuron synaptic transmissionGO:0007270690.020
regulation of membrane potentialGO:00423911920.020
organism emergence from protective structureGO:007168440.020
leukocyte differentiationGO:00025213420.019
rac protein signal transductionGO:0016601130.019
rho protein signal transductionGO:0007266320.019
exocytosisGO:00068871210.019
stem cell maintenanceGO:00198271300.019
chromatin disassemblyGO:003149810.019
protein alkylationGO:0008213810.019
establishment or maintenance of cytoskeleton polarityGO:003095220.019
mitochondrial transportGO:0006839360.019
regulation of cellular amine metabolic processGO:0033238200.018
organonitrogen compound biosynthetic processGO:19015661920.018
lipid localizationGO:00108761260.018
synaptic transmission gabaergicGO:0051932190.018
glycerophospholipid biosynthetic processGO:0046474320.018
carbohydrate metabolic processGO:00059752300.018
regulation of cell migrationGO:00303342190.018
negative regulation of mesenchymal cell proliferationGO:007220130.018
mitotic cell cycle processGO:19030471590.018
digestive system developmentGO:00551232000.018
positive regulation of meiosis iGO:006090350.018
positive regulation of protein phosphorylationGO:00019342420.017
regulation of secretion by cellGO:19035302490.017
asymmetric stem cell divisionGO:009872230.017
anion transportGO:00068201770.017
cellular protein catabolic processGO:00442571550.017
organelle assemblyGO:00709251770.017
modification dependent macromolecule catabolic processGO:00436321330.017
cell recognitionGO:0008037830.017
locomotory behaviorGO:00076261950.017
Fly
regulation of map kinase activityGO:00434051200.017
sequestering of metal ionGO:0051238190.017
proteolysis involved in cellular protein catabolic processGO:00516031470.017
synaptic vesicle recyclingGO:0036465190.017
synaptic vesicle membrane organizationGO:004849910.017
histone deacetylationGO:0016575260.016
regulation of lymphocyte activationGO:00512492400.016
regulation of cell cycle processGO:00105641600.016
regulation of cell activationGO:00508652890.016
immune effector processGO:00022523210.016
regulation of mesenchymal cell proliferation involved in lung developmentGO:200079020.016
cellular protein complex assemblyGO:00436231160.016
Fly
response to extracellular stimulusGO:00099911270.016
positive regulation of cell developmentGO:00107202370.016
regulation of cell projection organizationGO:00313442060.016
protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayGO:000184440.016
nuclear transportGO:00511691390.016
positive regulation of protein catabolic processGO:0045732600.016
homeostasis of number of cellsGO:00488722100.016
synaptic vesicle localizationGO:0097479590.016
positive regulation of nucleotide catabolic processGO:0030813880.016
regulation of cytoskeleton organizationGO:00514931220.015
Fly
female gamete generationGO:0007292740.015
Fly
ubiquitin dependent protein catabolic processGO:00065111290.015
modification dependent protein catabolic processGO:00199411330.015
positive regulation of protein modification processGO:00314012990.015
nucleoside monophosphate metabolic processGO:0009123850.015
tube closureGO:0060606910.015
microtubule cytoskeleton organizationGO:00002261570.015
negative regulation of transferase activityGO:0051348850.015
leukocyte mediated immunityGO:00024431740.015
synaptic vesicle transportGO:0048489570.015
microtubule based transportGO:0010970500.015
oxidation reduction processGO:00551143420.015
stem cell differentiationGO:00488632680.015
protein localization to nucleusGO:00345041210.015
positive regulation of purine nucleotide catabolic processGO:0033123880.015
positive regulation of cell deathGO:00109422240.015
Fly
muscle tissue developmentGO:00605373080.015
dna modificationGO:0006304500.015
protein targetingGO:00066051430.015
positive regulation of nucleotide metabolic processGO:00459811140.015
positive regulation of gtpase activityGO:0043547850.015
positive regulation of neuron differentiationGO:00456661410.015
blood vessel morphogenesisGO:00485142850.014
blood circulationGO:00080151950.014
oocyte constructionGO:000730820.014
epithelial tube formationGO:00721751300.014
embryonic epithelial tube formationGO:00018381300.014
oocyte axis specificationGO:000730920.014
regulation of defense responseGO:00313472330.014
regulation of cellular component biogenesisGO:00440871810.014
Fly
negative regulation of cell developmentGO:00107211690.014
synapse organizationGO:00508081250.014
Fly
lipid transportGO:0006869980.014
regulation of reactive oxygen species metabolic processGO:2000377400.014
regulation of transferase activityGO:00513382630.014
negative regulation of protein modification processGO:00314001630.014
rna interferenceGO:001624620.014
regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayGO:190073930.014
neural tube formationGO:00018411080.014
nitrogen compound transportGO:00717052710.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.014
canonical wnt signaling pathwayGO:00600701300.014
actin filament polymerizationGO:0030041440.014
Fly
positive regulation of apoptotic processGO:00430652170.014
actin cytoskeleton organizationGO:00300362200.014
Fly
mitochondrion transport along microtubuleGO:004749730.014
response to organonitrogen compoundGO:00102432460.014
regulation of protein transportGO:00512231630.013
meiotic cell cycleGO:00513211220.013
neural tube developmentGO:00219151600.013
multicellular organismal signalingGO:0035637910.013
regulation of cytokine productionGO:00018172660.013
response to peptideGO:19016521360.013
stem cell fate specificationGO:004886630.013
myeloid cell differentiationGO:00300992330.013
protein processingGO:00164851630.013
regulation of proteolysisGO:00301621640.013
hindbrain developmentGO:00309021280.013
peptidyl amino acid modificationGO:00181933360.013
meiotic cell cycle processGO:1903046770.013
regulation of leukocyte differentiationGO:19021051590.013
rna processingGO:00063961050.013
autophagyGO:0006914450.013
cytokine productionGO:00018163190.013
regulation of ras gtpase activityGO:0032318880.013
regulation of anatomical structure sizeGO:00900661780.013
Fly
positive regulation of cell projection organizationGO:0031346950.013
regulation of transcription during meiosisGO:005103710.013
carbohydrate derivative biosynthetic processGO:19011371830.013
regulation of blood pressureGO:0008217930.013
protein deacetylationGO:0006476320.013
ribonucleoside monophosphate metabolic processGO:0009161800.013
stress activated mapk cascadeGO:0051403800.013
negative regulation of cell migrationGO:0030336590.013
protein deacylationGO:0035601360.013
regulation of histone modificationGO:0031056560.013
axon cargo transportGO:0008088330.012
negative regulation of cell proliferationGO:00082852960.012
smad protein signal transductionGO:0060395210.012
regulation of receptor activityGO:0010469410.012
regulation of cellular ketone metabolic processGO:0010565660.012
neural tube closureGO:0001843900.012
vesicle organizationGO:0016050600.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
cofactor metabolic processGO:0051186800.012
histone h4 k12 acetylationGO:004398320.012
establishment of organelle localizationGO:00516561220.012
primary neural tube formationGO:0014020950.012
maintenance of locationGO:0051235890.012
protein polyubiquitinationGO:0000209330.012
positive regulation of cellular component biogenesisGO:0044089940.012
t cell activationGO:00421102890.012
chemotaxisGO:00069352470.012
single organism nuclear importGO:1902593950.012
establishment of synaptic vesicle localizationGO:0097480570.012
response to growth factorGO:00708481980.012
organic hydroxy compound transportGO:0015850930.012
adult locomotory behaviorGO:0008344910.012
regulation of actin polymerization or depolymerizationGO:0008064450.012
Fly
protein localization to plasma membraneGO:0072659570.012
renal system developmentGO:00720012250.012
regulation of cellular protein catabolic processGO:1903362610.012
extracellular matrix organizationGO:00301981470.012
transmission of nerve impulseGO:0019226760.011
cellular response to growth factor stimulusGO:00713631970.011
heart morphogenesisGO:00030071780.011
habituationGO:004695930.011
Fly
positive regulation of cell divisionGO:0051781310.011
negative regulation of kinase activityGO:0033673810.011
regulation of clathrin mediated endocytosisGO:200036940.011
blastocyst developmentGO:0001824800.011
neuromuscular processGO:0050905990.011
cell junction maintenanceGO:003433140.011
sensory perception of soundGO:0007605970.011
cell adhesionGO:00071553290.011
regulation of protein kinase activityGO:00458592320.011
circulatory system processGO:00030131970.011
intracellular receptor signaling pathwayGO:0030522740.011
cellular response to lipidGO:00713961450.011
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.011
regulation of protein serine threonine kinase activityGO:00719001570.011
regulation of cellular component sizeGO:00325351210.011
Fly
macromolecular complex disassemblyGO:0032984430.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
negative regulation of cell cycleGO:00457861230.011
jnk cascadeGO:0007254720.011
response to fibroblast growth factorGO:0071774470.011
proteasomal protein catabolic processGO:0010498980.011
conditioned taste aversionGO:000166140.011
circadian regulation of gene expressionGO:0032922480.011
actin filament organizationGO:00070151130.011
Fly
camera type eye developmentGO:00430102660.011
negative regulation of cell motilityGO:2000146610.011
cell type specific apoptotic processGO:00972852680.011
male meiosisGO:0007140370.011
gonad developmentGO:00084061410.011
hindbrain morphogenesisGO:0021575460.011
dephosphorylationGO:00163111290.010
mesodermal cell migrationGO:000807840.010
oocyte anterior posterior axis specificationGO:000731420.010
epithelial cell developmentGO:00020641590.010
positive regulation of cell cycleGO:0045787920.010
dna recombinationGO:0006310920.010
translationGO:0006412930.010
Fly
fat cell differentiationGO:00454441600.010
cellular response to hormone stimulusGO:00328701500.010
regulation of rho protein signal transductionGO:0035023710.010
myeloid cell homeostasisGO:00022621140.010
negative regulation of cell cycle processGO:0010948690.010
regulation of chromosome organizationGO:0033044830.010
regulation of chromatin organizationGO:1902275570.010
epithelial tube morphogenesisGO:00605623030.010

Atxn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.029
disease of anatomical entityDOID:700.029
neuromuscular diseaseDOID:44000.020
neuropathyDOID:87000.020
disease of cellular proliferationDOID:1456600.020
organ system cancerDOID:005068600.017
cancerDOID:16200.017
charcot marie tooth diseaseDOID:1059500.017
musculoskeletal system diseaseDOID:1700.014
bone diseaseDOID:008000100.014
connective tissue diseaseDOID:6500.014
bone development diseaseDOID:008000600.014
central nervous system diseaseDOID:33100.011
disease of metabolismDOID:001466700.010
inherited metabolic disorderDOID:65500.010