Mus musculus

60 known processes

Atxn3

ataxin 3

(Aliases: ATX3,Mjd,2210008M02Rik,ataxin-3,MJD1,AI647473,Sca3,AI463012)

Atxn3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
proteolysis involved in cellular protein catabolic processGO:00516031470.253
cellular macromolecule catabolic processGO:00442652060.217
protein catabolic processGO:00301632210.204
protein modification by small protein conjugationGO:00324461870.187
cellular protein catabolic processGO:00442571550.186
macromolecule catabolic processGO:00090572810.177
positive regulation of cellular catabolic processGO:00313311480.155
protein polyubiquitinationGO:0000209330.155
protein ubiquitinationGO:00165671710.153
modification dependent macromolecule catabolic processGO:00436321330.147
protein modification by small protein conjugation or removalGO:00706472070.141
modification dependent protein catabolic processGO:00199411330.108
amine metabolic processGO:0009308450.092
peptidyl amino acid modificationGO:00181933360.083
covalent chromatin modificationGO:00165691630.082
Rat
chromatin modificationGO:00165681870.080
Rat
regulation of cellular ketone metabolic processGO:0010565660.078
purine containing compound metabolic processGO:00725213110.072
purine containing compound catabolic processGO:00725232130.072
glycosyl compound metabolic processGO:19016572460.070
positive regulation of protein modification processGO:00314012990.070
purine ribonucleotide metabolic processGO:00091502900.069
ribonucleoside metabolic processGO:00091192450.066
aromatic compound catabolic processGO:00194392860.066
cellular amino acid metabolic processGO:00065201030.065
purine ribonucleoside metabolic processGO:00461282410.063
purine nucleoside triphosphate catabolic processGO:00091462030.061
purine nucleotide metabolic processGO:00061633020.061
ribonucleotide metabolic processGO:00092592910.058
nucleotide metabolic processGO:00091173320.056
cellular amine metabolic processGO:0044106440.056
regulation of cellular catabolic processGO:00313292420.056
heterocycle catabolic processGO:00467002800.055
positive regulation of cellular protein catabolic processGO:1903364340.054
nucleoside phosphate metabolic processGO:00067533380.054
regulation of cellular amine metabolic processGO:0033238200.053
nucleobase containing small molecule metabolic processGO:00550863520.053
ribose phosphate metabolic processGO:00196932910.052
transmembrane transportGO:00550854120.052
purine nucleoside triphosphate metabolic processGO:00091442260.051
membrane organizationGO:00610242450.050
cellular nitrogen compound catabolic processGO:00442702800.049
cellular response to dna damage stimulusGO:00069742070.048
purine nucleoside catabolic processGO:00061522050.046
regulation of cellular amino acid metabolic processGO:000652150.045
organophosphate catabolic processGO:00464342320.045
purine nucleoside metabolic processGO:00422782410.044
cellular ketone metabolic processGO:0042180840.044
nucleoside monophosphate metabolic processGO:0009123850.044
nucleoside catabolic processGO:00091642060.044
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.043
carbohydrate derivative catabolic processGO:19011362310.043
ribonucleoside triphosphate metabolic processGO:00091992200.042
nucleoside metabolic processGO:00091162460.042
purine ribonucleoside triphosphate catabolic processGO:00092071990.041
carbohydrate metabolic processGO:00059752300.041
ubiquitin dependent protein catabolic processGO:00065111290.041
histone modificationGO:00165701590.041
Rat
regulation of proteolysisGO:00301621640.041
chromatin organizationGO:00063252060.040
Rat
positive regulation of protein catabolic processGO:0045732600.040
negative regulation of cellular protein metabolic processGO:00322692470.039
ribonucleoside catabolic processGO:00424542060.039
positive regulation of proteolysisGO:0045862850.039
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.039
spermatogenesisGO:00072832840.038
cellular lipid metabolic processGO:00442553230.038
positive regulation of cellular amino acid metabolic processGO:004576430.037
purine ribonucleotide catabolic processGO:00091542080.037
organonitrogen compound catabolic processGO:19015652640.037
nucleoside triphosphate catabolic processGO:00091432050.037
carbohydrate derivative biosynthetic processGO:19011371830.037
endocytosisGO:00068971680.036
regulation of cellular component biogenesisGO:00440871810.036
nucleoside phosphate catabolic processGO:19012922220.036
ribonucleotide catabolic processGO:00092612080.036
ribonucleoside triphosphate catabolic processGO:00092031990.035
male gamete generationGO:00482322850.035
glycosyl compound catabolic processGO:19016582060.035
fertilizationGO:00095661270.034
urogenital system developmentGO:00016552610.034
negative regulation of intracellular signal transductionGO:19025321670.034
positive regulation of apoptotic processGO:00430652170.034
positive regulation of cellular amine metabolic processGO:003324050.034
purine nucleotide catabolic processGO:00061952110.033
regulation of cellular protein catabolic processGO:1903362610.033
glycoprotein biosynthetic processGO:0009101890.033
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.032
learning or memoryGO:00076111480.032
cognitionGO:00508901490.032
proteasomal protein catabolic processGO:0010498980.031
regulation of organelle organizationGO:00330432890.031
nucleoside triphosphate metabolic processGO:00091412300.030
protein processingGO:00164851630.030
positive regulation of protein modification by small protein conjugation or removalGO:1903322300.030
gland developmentGO:00487323300.030
nucleotide catabolic processGO:00091662170.030
organelle assemblyGO:00709251770.029
positive regulation of cell deathGO:00109422240.029
purine ribonucleoside triphosphate metabolic processGO:00092052200.029
protein glycosylationGO:0006486550.029
positive regulation of programmed cell deathGO:00430682180.029
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787250.029
purine ribonucleoside catabolic processGO:00461302050.028
regulation of protein complex assemblyGO:0043254830.028
cellular response to external stimulusGO:0071496880.027
regulation of hydrolase activityGO:00513362460.027
positive regulation of organelle organizationGO:00106381280.027
immune effector processGO:00022523210.027
mitochondrion organizationGO:00070051340.027
positive regulation of protein ubiquitinationGO:0031398270.027
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.027
regulation of protein modification by small protein conjugation or removalGO:1903320570.027
dna metabolic processGO:00062593030.026
ribonucleoside monophosphate metabolic processGO:0009161800.026
cation transmembrane transportGO:00986552660.026
purine ribonucleoside monophosphate metabolic processGO:0009167800.026
protein oligomerizationGO:0051259670.026
cation transportGO:00068123990.025
regulation of protein ubiquitinationGO:0031396520.025
multicellular organismal homeostasisGO:00488711640.025
negative regulation of cellular component organizationGO:00511291940.025
regulation of cell cycleGO:00517262810.025
macromolecule glycosylationGO:0043413550.025
response to growth factorGO:00708481980.025
positive regulation of hydrolase activityGO:00513451480.025
leukocyte differentiationGO:00025213420.024
cellular response to topologically incorrect proteinGO:0035967250.024
intracellular protein transportGO:00068862040.023
cytoplasmic transportGO:00164822340.023
regulation of transferase activityGO:00513382630.023
regulation of cell activationGO:00508652890.022
protein localization to organelleGO:00333651850.022
dna repairGO:00062811070.022
negative regulation of protein metabolic processGO:00512482820.022
positive regulation of protein phosphorylationGO:00019342420.022
inorganic ion transmembrane transportGO:00986602340.022
cellular response to growth factor stimulusGO:00713631970.022
sensory perceptionGO:00076002450.021
ion transmembrane transportGO:00342203610.021
cellular component assembly involved in morphogenesisGO:00109271390.021
regulation of protein catabolic processGO:00421761080.021
translationGO:0006412930.021
response to extracellular stimulusGO:00099911270.021
regulation of apoptotic signaling pathwayGO:20012331970.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.021
mapk cascadeGO:00001652810.020
cellular response to transforming growth factor beta stimulusGO:0071560880.020
skeletal system developmentGO:00015013560.020
protein autophosphorylationGO:0046777610.020
organonitrogen compound biosynthetic processGO:19015661920.020
cellular protein complex assemblyGO:00436231160.020
negative regulation of molecular functionGO:00440922580.019
nitrogen compound transportGO:00717052710.019
positive regulation of transferase activityGO:00513471670.019
inorganic cation transmembrane transportGO:00986622070.019
methylationGO:00322591340.019
cellular homeostasisGO:00197252400.019
myeloid cell differentiationGO:00300992330.019
response to misfolded proteinGO:005178850.019
single fertilizationGO:0007338820.019
macromolecule methylationGO:00434141200.018
axonogenesisGO:00074092740.018
regulation of lymphocyte activationGO:00512492400.018
regulation of protein kinase activityGO:00458592320.018
fat cell differentiationGO:00454441600.018
regulation of chromosome organizationGO:0033044830.018
protein maturationGO:00516041760.018
wound healingGO:00420601570.017
regulation of ion transportGO:00432692150.017
ras protein signal transductionGO:0007265770.017
atp metabolic processGO:0046034750.017
positive regulation of protein kinase activityGO:00458601440.017
rhythmic processGO:00485111740.017
nucleoside monophosphate catabolic processGO:0009125590.017
ovulation cycleGO:0042698590.017
response to transforming growth factor betaGO:0071559880.017
chemotaxisGO:00069352470.017
actin cytoskeleton organizationGO:00300362200.017
Human
positive regulation of cellular component biogenesisGO:0044089940.017
intracellular receptor signaling pathwayGO:0030522740.017
organophosphate biosynthetic processGO:00904071220.017
purine nucleoside monophosphate metabolic processGO:0009126810.017
regulation of purine nucleotide metabolic processGO:19005421690.017
glycosylationGO:0070085620.016
posttranscriptional regulation of gene expressionGO:00106081550.016
multicellular organism growthGO:00352641610.016
regulation of cell migrationGO:00303342190.016
lateral inhibitionGO:004633110.016
regulation of chromatin organizationGO:1902275570.016
endomembrane system organizationGO:00102561470.016
protein localization to membraneGO:00726571080.016
response to inorganic substanceGO:0010035960.016
regulation of membrane potentialGO:00423911920.016
organic hydroxy compound metabolic processGO:19016152030.015
oxidation reduction processGO:00551143420.015
divalent metal ion transportGO:00708381720.015
organelle disassemblyGO:190300820.015
organelle localizationGO:00516401790.015
circadian rhythmGO:00076231140.015
small gtpase mediated signal transductionGO:0007264970.015
sensory perception of mechanical stimulusGO:00509541070.015
regulation of protein transportGO:00512231630.015
regulation of nucleotide metabolic processGO:00061401690.015
glycoprotein metabolic processGO:00091001160.015
tissue homeostasisGO:00018941150.015
negative regulation of immune system processGO:00026832090.015
organic cyclic compound catabolic processGO:19013612950.015
neuron apoptotic processGO:00514021420.015
stem cell differentiationGO:00488632680.015
cellular response to cytokine stimulusGO:00713451890.015
striated muscle tissue developmentGO:00147062930.015
regulation of cell motilityGO:20001452360.015
anion transportGO:00068201770.015
cellular response to starvationGO:0009267570.015
positive regulation of cell activationGO:00508671580.015
lipid biosynthetic processGO:00086101790.015
meiotic cell cycleGO:00513211220.014
positive regulation of purine nucleotide catabolic processGO:0033123880.014
positive regulation of protein complex assemblyGO:0031334450.014
cytokine productionGO:00018163190.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.014
regulation of map kinase activityGO:00434051200.014
negative regulation of phosphorylationGO:00423261660.014
regulation of chromatin modificationGO:1903308570.014
development of primary sexual characteristicsGO:00451371430.014
muscle cell differentiationGO:00426922610.014
regulation of stress activated mapk cascadeGO:0032872690.014
skeletal muscle organ developmentGO:00605381630.014
cellular carbohydrate metabolic processGO:00442621190.014
stress activated mapk cascadeGO:0051403800.014
protein polymerizationGO:0051258570.014
metal ion homeostasisGO:00550651890.014
transforming growth factor beta receptor signaling pathwayGO:0007179710.014
muscle tissue developmentGO:00605373080.014
mitotic cell cycleGO:00002781950.014
cellular ion homeostasisGO:00068731650.014
regulation of cytoskeleton organizationGO:00514931220.014
heart morphogenesisGO:00030071780.014
atp catabolic processGO:0006200550.014
cell growthGO:00160491300.014
g protein coupled receptor signaling pathwayGO:00071862430.013
divalent inorganic cation transportGO:00725111780.013
organic anion transportGO:00157111370.013
action potentialGO:0001508780.013
rho protein signal transductionGO:0007266320.013
actin filament organizationGO:00070151130.013
positive regulation of lymphocyte activationGO:00512511400.013
organelle fissionGO:00482851700.013
cellular response to lipidGO:00713961450.013
anatomical structure homeostasisGO:00602491450.013
regulation of t cell activationGO:00508631700.013
purine nucleoside monophosphate catabolic processGO:0009128580.013
ribonucleoside monophosphate catabolic processGO:0009158570.013
gonad developmentGO:00084061410.013
ear developmentGO:00435832000.013
reactive oxygen species metabolic processGO:0072593840.013
response to radiationGO:00093141650.013
purine ribonucleoside monophosphate catabolic processGO:0009169570.013
negative regulation of organelle organizationGO:0010639900.013
cellular chemical homeostasisGO:00550822150.013
regulation of endopeptidase activityGO:0052548890.013
regulation of cell projection organizationGO:00313442060.013
viral processGO:0016032410.013
negative regulation of cellular amine metabolic processGO:003323910.013
regulation of mapk cascadeGO:00434082480.013
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:2000058140.013
microtubule based processGO:00070172360.013
Human
locomotory behaviorGO:00076261950.013
interspecies interaction between organismsGO:0044419830.013
regulation of nucleoside metabolic processGO:00091181300.013
developmental maturationGO:00217001930.013
symbiosis encompassing mutualism through parasitismGO:0044403830.012
nucleocytoplasmic transportGO:00069131390.012
renal system developmentGO:00720012250.012
phospholipid metabolic processGO:0006644870.012
b cell activationGO:00421131610.012
cell type specific apoptotic processGO:00972852680.012
cation homeostasisGO:00550802120.012
protein homooligomerizationGO:0051260430.012
er nucleus signaling pathwayGO:0006984270.012
regulation of cellular component sizeGO:00325351210.012
dendrite developmentGO:00163581150.012
ossificationGO:00015032160.012
apoptotic mitochondrial changesGO:0008637480.012
maintenance of locationGO:0051235890.012
viral gene expressionGO:001908030.012
cellular response to misfolded proteinGO:007121850.012
positive regulation of nervous system developmentGO:00519622210.012
camera type eye developmentGO:00430102660.012
actin filament polymerizationGO:0030041440.012
regulation of cytokine productionGO:00018172660.012
negative regulation of protein modification processGO:00314001630.012
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.012
negative regulation of apoptotic signaling pathwayGO:20012341040.012
homeostasis of number of cellsGO:00488722100.012
negative regulation of cell cycleGO:00457861230.012
regulation of cell adhesionGO:00301551540.012
response to nutrient levelsGO:00316671090.012
compound eye developmentGO:004874910.012
synaptic transmissionGO:00072683290.012
Worm
organ growthGO:00352651170.012
regulation of cell growthGO:0001558910.012
b cell differentiationGO:0030183780.012
regulation of peptidase activityGO:0052547960.012
intracellular steroid hormone receptor signaling pathwayGO:0030518290.012
embryonic organ morphogenesisGO:00485622760.012
germ cell developmentGO:00072811850.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
regulation of lipid metabolic processGO:00192161180.011
negative regulation of cytoskeleton organizationGO:0051494360.011
nuclear divisionGO:00002801580.011
negative regulation of cellular amino acid metabolic processGO:004576300.011
carbohydrate homeostasisGO:00335001280.011
mrna metabolic processGO:0016071840.011
lymphocyte proliferationGO:00466511640.011
epithelial cell developmentGO:00020641590.011
digestive system developmentGO:00551232000.011
cellular response to nutrient levelsGO:0031669640.011
negative regulation of cell proliferationGO:00082852960.011
mitochondrial transportGO:0006839360.011
regulation of nucleotide catabolic processGO:00308111220.011
protein deubiquitinationGO:0016579190.011
response to acid chemicalGO:00011011110.011
cellular response to hormone stimulusGO:00328701500.011
regulation of proteasomal protein catabolic processGO:0061136460.011
organelle membrane fusionGO:009017410.011
long term memoryGO:0007616150.011
dephosphorylationGO:00163111290.011
regulation of protein localizationGO:00328802310.011
regulation of protein serine threonine kinase activityGO:00719001570.011
meiotic nuclear divisionGO:00071261150.011
regulation of neuron deathGO:19012141340.011
microtubule cytoskeleton organization involved in mitosisGO:190285040.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
t cell activationGO:00421102890.011
nuclear importGO:0051170950.011
protein localization to nucleusGO:00345041210.011
positive regulation of nucleotide metabolic processGO:00459811140.011
respiratory system developmentGO:00605411900.011
regulation of histone modificationGO:0031056560.011
detection of stimulusGO:0051606840.011
embryonic epithelial tube formationGO:00018381300.011
microtubule cytoskeleton organizationGO:00002261570.011
Human
intrinsic apoptotic signaling pathwayGO:00971931320.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
positive regulation of chromatin modificationGO:1903310280.011
regulation of purine nucleotide catabolic processGO:00331211220.011
calcium ion transportGO:00068161590.011
transmission of nerve impulseGO:0019226760.011
actin filament bundle assemblyGO:0051017400.011
calcium ion homeostasisGO:00550741270.011
apoptotic signaling pathwayGO:00971903060.011
carbohydrate transportGO:0008643620.011
negative regulation of neuron deathGO:1901215980.011
response to light stimulusGO:00094161350.011
regulation of ion transmembrane transportGO:00347651190.010
cellular calcium ion homeostasisGO:00068741190.010
sperm motilityGO:0030317470.010
response to molecule of bacterial originGO:00022371430.010
regulation of transmembrane transportGO:00347621280.010
regulation of leukocyte differentiationGO:19021051590.010
mitotic cell cycle processGO:19030471590.010
neural tube developmentGO:00219151600.010
guanosine containing compound catabolic processGO:19010691440.010
regulation of establishment of protein localizationGO:00702011810.010
positive regulation of nucleoside metabolic processGO:0045979910.010
canonical wnt signaling pathwayGO:00600701300.010
small molecule biosynthetic processGO:00442831320.010
leukocyte activation involved in immune responseGO:00023661260.010
response to endoplasmic reticulum stressGO:0034976530.010
lymphocyte differentiationGO:00300982420.010
inflammatory responseGO:00069542440.010

Atxn3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.041
Human
disease of anatomical entityDOID:700.041
Human
central nervous system diseaseDOID:33100.030
Human
neurodegenerative diseaseDOID:128900.022
Human
disease of cellular proliferationDOID:1456600.020
cancerDOID:16200.015
organ system cancerDOID:005068600.014